Trichoblastoma with Abundant Plump Stromal Cells in a Dog
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- MINESHIGE Takayuki
- Research Institute of Biosciences, Azabu University, 1–17–71 Fuchinobe, Chuo-ku, Sagamihara, Kanagawa 252–5201, Japan
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- YASUNO Kyohei
- Research Institute of Biosciences, Azabu University, 1–17–71 Fuchinobe, Chuo-ku, Sagamihara, Kanagawa 252–5201, Japan
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- SUGAHARA Go
- Research Institute of Biosciences, Azabu University, 1–17–71 Fuchinobe, Chuo-ku, Sagamihara, Kanagawa 252–5201, Japan
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- TOMISHITA Yoshifumi
- Tomishita Animal Hospital, 2–17 Matsuomachi, Yahatahigashi-ku, Kitakyushu, Fukuoka 805–0032, Japan
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- SHIMOKAWA Namiko
- MONOLIS Co., Ltd., 8–31–6 Jindaijihigashimachi, Chofu, Tokyo 182–0012, Japan
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- KAMIIE Junichi
- Laboratory of Veterinary Pathology, School of Veterinary Medicine, Azabu University, 1–17–71 Fuchinobe, Chuo-ku, Sagamihara, Kanagawa 252–5201, Japan
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- NISHIFUJI Koji
- Division of Animal Life Science, Graduate School, Tokyo University of Agriculture and Technology, 3–5–8 Saiwai-cho, Fuchu, Tokyo 183–8509, Japan
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- SHIROTA Kinji
- Research Institute of Biosciences, Azabu University, 1–17–71 Fuchinobe, Chuo-ku, Sagamihara, Kanagawa 252–5201, Japan Laboratory of Veterinary Pathology, School of Veterinary Medicine, Azabu University, 1–17–71 Fuchinobe, Chuo-ku, Sagamihara, Kanagawa 252–5201, Japan
Bibliographic Information
- Other Title
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- Pathology : Trichoblastoma with Abundant Plump Stromal Cells in a Dog
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Abstract
Histopathological and immunohistochemical examinations were made on a cutaneous tumor on the head of an 11-year-old female mixed-breed dog. The tumor was well demarcated and comprised multilobular structures of neoplastic epithelial cells with abundant plump peritumoral stromal cells. The neoplastic cells formed irregular cell cords or trabeculae and were arranged in characteristic palisades at the periphery. Immunohistochemically, neoplastic cells were positive for p63 and the several cytokeratins examined. In contrast, the plump peritumoral stromal cells were positive for vimentin and unevenly for nestin, a neuroepithelial stem cell protein. The stromal cells prominently proliferated in proximity to epithelial neoplastic cells, suggesting a close interaction between these two cell types.
Journal
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- Journal of Veterinary Medical Science
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Journal of Veterinary Medical Science 76 (5), 735-739, 2014
JAPANESE SOCIETY OF VETERINARY SCIENCE
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Details
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- CRID
- 1390001206428956416
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- NII Article ID
- 130003391265
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- NII Book ID
- AA10796138
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- COI
- 1:STN:280:DC%2BC2czlslOhtA%3D%3D
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- ISSN
- 13477439
- 09167250
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- NDL BIB ID
- 025556431
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- PubMed
- 24430656
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
- KAKEN
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- Abstract License Flag
- Disallowed