Rchr
J-GLOBAL ID:201401094843361571   Update date: Jan. 30, 2024

Amano Takanori

アマノ タカノリ | Amano Takanori
Affiliation and department:
Job title: Team leader
Research field  (2): Genetics ,  Genomics
Research keywords  (4): complex diseases ,  disease model mouse ,  enhancer ,  gene regulation
Research theme for competitive and other funds  (5):
  • 2019 - 2022 Modeling complex diseases using mouse subspecies strains
  • 2015 - 2018 Cis-regulatory polymorphism responsible for allele-expression-bias that contributes to mouse phenotype
  • 2016 - 2018 エンハンサーの共有と遮蔽を支える染色体ダイナミクス
  • 2012 - 2015 Transcriptional regulation of Shh via chromosomal dynamics
  • 2010 - 2012 Shh肢芽エンハンサー結合因子の網羅的探索
Papers (25):
more...
MISC (11):
  • Kousuke Mouri, Tomoko Sagai, Takanori Amano, Toshihiko Shiroishi. Orientation-dependent enhancer evoked by chromosomal translocation in mouse Hm mutation. MECHANISMS OF DEVELOPMENT. 2017. 145. S139-S139
  • Takanori Amano, Toshihiko Shiroishi. Cis-regulatory polymorphism of Shh is involved in variation of shape and size of the mouse stomach. GENES & GENETIC SYSTEMS. 2016. 91. 6. 351-351
  • Tomoko Sagai, Takanori Amano, Akiteru Maeno, Youichi Mizushina, Hiromi Nakazawa, Toshihiko Shiroishi. Dosage effect of two Shh enhancers for control of tooth number in mouse. GENES & GENETIC SYSTEMS. 2016. 91. 6. 353-353
  • Kousuke Mouri, Tomoko Sagai, Takanori Amano, Toshihiko Shiroishi. Enhancer rearrangement causes regulatory change of gene expression. GENES & GENETIC SYSTEMS. 2016. 91. 6. 373-373
  • Takanori Amano. A genome-editing approach using the CRISPR/Cas9 system reveals the cis-regulatory landscape of the mouse Shh locus. GENES & GENETIC SYSTEMS. 2015. 90. 6. 362-362
more...
Patents (1):
  • 大腸癌モデル動物、大腸癌モデル動物の製造方法、抗癌剤、アレルギーモデル動物、アレルギーモデル動物の製造方法、及びスクリーニング方法
Books (4):
  • 遺伝学用語集 遺伝単
    株式会社エヌ・ティー・エス 2017
  • 進化するゲノム編集技術
    株式会社エヌ・ティー・エス 2015
  • 生物の科学 遺伝
    株式会社エヌ・ティー・エス 2013
  • 生物機能モデルと新しいリソース・リサーチツール
    株式会社エル・アイ・シー 2011
Lectures and oral presentations  (18):
  • Shh遺伝子の発現を制御する染色体高次構造の動態
    (東北大学加齢医学研究所研究員会セミナー 2011)
  • Long-rangeエンハンサーによるShh遺伝子の発現制御
    (みんなで建設的に考える会 2011)
  • A BAC-transgenic mouse model for the long-range enhancer-promoter interaction at the Shh locus
    (2011)
  • A mouse mutation Rim4 with duplication of a 7Mb segment of chromosome 8 is model of Partial trisomy 4q-ter syndrome that exhibits congenital malformation
    (23th INTERNATIONAL MOUSE GENOME CONFERENCE 2009 2009)
  • Long-range enhancer-promoter interaction via chromosomal dynamics at the Shh locus
    (23th INTERNATIONAL MOUSE GENOME CONFERENCE 2009 2009)
more...
Education (3):
  • 2002 - 2005 Tohoku University Graduate School of Life Sciences Department of Developmental Biology and Neurosciences
  • 2000 - 2002 Tohoku University Graduate School of Science Department of Biology
  • 1996 - 2000 Tohoku University Faculty of Science Department of Biology
Professional career (1):
  • Ph.D. (Tohoku University)
Work history (3):
  • 2018/07 - 現在 RIKEN BioResource Research Center Next Generation Human Disease Model Team Team Leader
  • 2013/11 - 2018/03 National Institute of Genetics Mammalian Genetics Laboratory Assistant professor
  • 2005/04 - 2013/10 National Institute of Genetics Mammalian Genetics Laboratory Research postdoc
Association Membership(s) (2):
THE GENETICS SOCIETY OF JAPAN ,  JAPANESE SOCIETY OF DEVELOPMENTAL BIOLOGISTS
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