Abstract
Background
Cotyledonoid dissecting leiomyoma (Sternberg tumor) is a rare variant of the uterine smooth muscle tumor. Although this tumor is a benign tumor clinically and pathologically, the appearance and growth pattern is unusual, so it may be misdiagnosed as malignancy.
Case reports
We report two cases of cotyledonoid dissecting leiomyoma of the uterus that occurred in two 44- and 31-year-old women, respectively. Total hysterectomy and bilateral salpingo-oophorectomy were performed in one of the patients, and myomectomy was done in the other one. Macroscopically, both tumors were grape-like exophytic masses resembling placental tissue. The patients were well after surgery, and one patient gave birth. To our knowledge, this is the first case report of a successful delivery after myomectomy of this tumor.
Conclusion
To prevent aggressive surgery it is important to recognize that this tumor is a benign and unusual appearing variant of leiomyoma. A fertility-sparing surgical procedure should be considered if the patient wishes to preserve her fertility.
Similar content being viewed by others
References
Roth LM, Reed RJ, Sternberg WH (1996) Cotyledonoid dissecting leiomyoma of the uterus: the sternberg tumour. Am J Surg Pathol 20:1455–1461
Saeed AS, Hanaa B, Faisal AS, Najla AM (2006) Cotyledonoid dissecting leiomyoma of the uterus: a case report of a benign uterine tumor with sarcoma-like gross appearance and review of literature. Int J Gynecol Pathol 25(3):262–267
Roth LM, Reed RJ (2000) Cotyledonoid leiomyoma of the uterus: report of a case. Int J Gynecol Pathol 19:272–276
World health organization classification of tumours (2003). In: Pathology & Genetics. Tumours of the breast and female genital organs. 241
Shelekhova KV, Kazakov DV, Michal M (2007) Cotylednoid dissecting leiomyoma of the uterus with intravascular growth: report of two cases. Virchows Arch 450(1):119–121
Weissferdt A, Maheshwari MB, Downey GP, Ganesan R, Rollason TP (2007) Cotyledonoid dissecting leiomyoma of the uterus: a case report. Diagn Pathol 2:18
Raga F, Sanz-Cortes M, Casan EM et al (2009) Cotyledonoid dissecting leiomyoma of the uterus. Fertil Steril 91(4):1269–1270
Driss M, Zhioua F, Doghri R, Mrad K, Dhouib R, Romdhane KB (2009) Cotyledonoid dissecting leiomyoma of the uterus associated with endosalpingiosis. Arch Gynecol Obstet 280:1063–1065
Fukunaga M, Suzuki K, Hiruta N (2010) Cotyledonoid dissecting leiomyoma of the uterus: a report of four cases. APMIS 118:331–333
Adedipe TO, Vine SJ (2010) Dissecting cotyledonoid leiomyoma: a rare cause of chronic intractable menorrhagia (not amenable to medical treatment) case report. Eur J Gynaecol Oncol 31(2):230–232
Soleymani Majd H, Ismail L, Desai SA, Reginald PW (2011) Epithelioid cotyledonoid dissecting leiomyoma: a case report and review of the literature. Arch Gynecol Obstet 283(4):771–774
Gezginç K, Yazici F, Selimoğlu R, Tavli L (2011) Cotyledonoid dissecting leiomyoma of the uterus with intravascular growth in postmenopausal woman: a case presentation. Int J Clin Oncol 16(6):701–704
Ersöz S, Turgutalp H, Mungan S, Güvendi G, Güven S (2011) Cotyledonoid leiomyoma of uterus: a case report. Turk Patholoji Derg 27(3):257–260
Roth LM, Kirker JA, Insull M, Whittaker J (2013) Recurrent cotyledonoid dissecting leiomyoma of the uterus. Int J Gynecol Pathol 32(2):215–220
Mathew M, Gowri V, Rao K, Machado L, AI Hamdani A, Shabnam S (2007) Cotyledonoid leiomyoma in pregnancy. Obstet Gynecol 109:509–511
Jordan LB, Al-Nafussi A, Beattie G (2002) Cotyledonoid hydropic intravenous leiomyomatosis: a new variant leiomyoma. Histopathology 40:245–252
Preda L, Rizzo S, Gorone MS, Fasani R, Maggioni A, Bellomi M (2009) MRI features of cotyledonoid dissecting leiomyoma of the uterus. Tumori 95(4):532–534
Conflict of interest
The authors declare that they have no conflict of interest.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Saeki, H., Suzuki, C., Yamasaki, S. et al. Cotyledonoid dissecting leiomyoma of the uterus: report of two cases. Arch Gynecol Obstet 291, 357–361 (2015). https://doi.org/10.1007/s00404-014-3406-2
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00404-014-3406-2