Molecular basis of mechanisms underlying transplacental drugtransfer in corporation with placental endocrine function
Project/Area Number |
23790199
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Medical pharmacy
|
Research Institution | Keio University |
Principal Investigator |
|
Project Period (FY) |
2011 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2011: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
|
Keywords | 胎盤関門 / 内分泌 / トランスポーター |
Research Abstract |
Organic anion transporter (OAT) 4 expressed at the basolateral membrane of the placental barrier appears to play a principal role in the uptake of 16α-OH DHEAS and contribute to the E3 synthesis during pregnancy. Moreover, the expression of OAT4
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Report
(3 results)
Research Products
(23 results)