Molecular mechanism for sustention of placental function by ezrinand a new approach to prevention of fetal growth retardation
Project/Area Number |
23790606
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Applied pharmacology
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Research Institution | Keio University |
Principal Investigator |
KOSE Noriko 慶應義塾大学, 薬学部, 研究員 (60348612)
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Project Period (FY) |
2011 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
|
Keywords | 薬物代謝酵素 / トランスポーター / 血液胎盤関門 / 胎児成長 / エズリン / ヒポタウリン / 胎盤関門 |
Research Abstract |
We analyzed the mechanisms of hypotaurine deficiency in the placenta of ezrin (Vil2) gene knockout mouse which shows fetal growth retardation. The results indicate that hypotaurine concentration in the placenta is mainly supplied by membrane transport
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Report
(3 results)
Research Products
(20 results)
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[Presentation]2012
Author(s)
Sugita Y, Higuchi K, Kamata K, Nishimura T, Kose N, Sai Y, Tomi M, Nakashima E
Organizer
International Symposium on Past, Present and Future of Molecular Pharmacokinetics
Place of Presentation
Tokyo Japan
Related Report
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[Presentation]2012
Author(s)
Duereh M, Higuchi K, Nishimura T, Kose N, Tomi M, Nakashima E
Organizer
International Symposium on Past, Present and Future of Molecular Pharmacokinetics
Place of Presentation
Tokyo Japan
Related Report
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[Presentation]2011
Author(s)
Asada T, Takanohashi T, Nishimura T, Kose N, Tomi M, Nakashima E.
Organizer
26th JSSX Annual Meeting
Place of Presentation
Hiroshima Japan
Related Report
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[Presentation]2011
Author(s)
Sugita Y, Higuchi K, Kamata K, Nishimura T, Kose N, Sai Y, Tomi M, Nakashima E
Organizer
Asian Federation for Pharmaceutical Sciences 2011
Place of Presentation
Kuala Lumpur Malaysia
Related Report
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[Presentation]2011
Author(s)
Oda K, Nishimura T, Kose N, Tomi M, Nakashima E
Organizer
Asian Federation for Pharmaceutical Sciences 2011
Place of Presentation
Kuala Lumpur Malaysia
Related Report
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[Presentation]2011
Author(s)
Duereh M, Nishimura T, Sugita Y, Kose N, Tomi M, Nakashima E
Organizer
Asian Federation for Pharmaceutical Sciences 2011
Place of Presentation
Kuala Lumpur Malaysia
Related Report
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[Presentation]2011
Author(s)
西村友宏, 田中純, 登美斉俊, 巨勢典子, 中島恵美
Organizer
日本薬剤学会第26年会
Place of Presentation
東京
Related Report
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[Presentation]2011
Author(s)
小田憲司, 西村友宏, 巨勢典子, 登美斉俊, 中島恵美
Organizer
日本薬剤学会第26年会
Place of Presentation
東京
Related Report
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[Presentation]2011
Author(s)
杉田友紀, 鎌田可奈子, 西村友宏, 巨勢典子, 崔 吉道, 登美斉俊, 中島恵美
Organizer
第6回トランスポーター研究会年仙台
Place of Presentation
仙台
Related Report
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[Presentation]2011
Author(s)
小田憲司, 西村友宏, 巨勢典子, 登美斉俊, 中島恵美
Organizer
第6回トランスポーター研究会年会
Place of Presentation
仙台
Related Report
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