Research keywords (8):
癌
, 脳
, 放射性医薬品
, ポジトロン
, Cancer
, Brain
, Radiopharmaceutical
, Positron
Research theme for competitive and other funds (39):
2019 - 2022 Development of PET diagnosis for successful BNCT and proton beam therapy
2016 - 2019 Molecular imaging of adenosine A2A receptor: a first-in-human study
2014 - 2017 Relationship between compensation for brain dysfunction and distribution of beta-amyloid in Lewy body disease
2013 - 2017 Development of fluorine-18 labeled 4DST derivatives for clinical use
2012 - 2016 Molecular imaging of metablotropic glutamate receptor type 1 – a first-in-human study
2011 - 2013 A PET study for relation of adenosine receptors with involuntary movements in Parkinson's disease
2011 - 2013 Development of PET molecular probes for imaging alpha-synuclein in the brain
2010 - 2012 Development of cancer diagnosis method based on the quantitative measurement of DNA synthesis rate by means of positron emission tomography.
2009 - 2010 Cerebral alteration in patients with glaucoma
2008 - 2010 Organization of PET brain bank
2007 - 2008 PET guided target therapy for malignantbrain tumor using carrier mediated transport of boronated radiolabelled pharmaceuticaland boron neutron capture therapy.
2006 - 2007 Development of the algorithm for quantitative neuroreceptor imaging using PET without serial arterial blood sampling and reference region
2004 - 2006 New PET diagnosis of adenosine receptors in the brain, heart and skeletal muscle
2005 - 2005 トランスレーショナルPET研究の有用性の確立と安全性基準
2004 - 2005 Detailed imaging of cerebral glucose metabolism for dementia diagnosis including omission of arterial blood sampling and correction of partial volume effect
2002 - 2004 A study of the histamine neuron system : Its correlation to newly-discovered hypothalamic peptides.
2001 - 2003 脳シグマ受容体を指標にした加齢・神経変性疾患・脳腫瘍の新しいPET診断法
2000 - 2001 Non-invasive measurement of cerebral inhibitory receptors and their neural circuit in epileptgenic
2000 - 2001 Investigation of Basal Ganglia Function and Intrinsic Dopamine Release by Positron Emission Tomography
1998 - 1999 In vivo PET measurement of expression of dopamine D2 receptor gene injected into rat striatum
1998 - 1999 Proposal of adenosine receptor ligands as new diagnostic probes for myocaridial function by PET
Development of radiopharmaceuticals for diagnosis of the brain and cancer by positron emission on tomography
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Papers (350):
Kenji Ishibashi, Yoshiharu Miura, Kei Wagatsuma, Jun Toyohara, Kiichi Ishiwata, Kenji Ishii. Adenosine A 2A Receptor Occupancy by Caffeine After Coffee Intake in Parkinson's Disease. Movement Disorders. 2022. 37. 4. 853-857
Jun Toyohara, Muneyuki Sakata, Kei Wagatsuma, Tetsuro Tago, Kenji Ishibashi, Kenji Ishii, Philip Elsinga, Kiichi Ishiwata. Test-retest reproducibility of cerebral adenosine A2A receptor quantification using [11C]preladenant. Annals of Nuclear Medicine. 2021
Kenji Ishibashi, Yoshiharu Miura, Kei Wagatsuma, Jun Toyohara, Kiichi Ishiwata, Kenji Ishii. Adenosine A2A Receptor Occupancy by Long-Term Istradefylline Administration in Parkinson's Disease. Movement disorders : official journal of the Movement Disorder Society. 2021. 36. 1. 268-269
Jun Toyohara, Norihiro Harada, Takeharu Kakiuchi, Hiroyuki Ohba, Masakatsu Kanazawa, Tetsuro Tago, Muneyuki Sakata, Kiichi Ishiwata. Synthesis and evaluation of N-isopropyl-p-[11C]methylamphetamine as a novel cerebral blood flow tracer for positron emission tomography. EJNMMI research. 2020. 10. 1. 115-115
Jun Toyohara, Tetsuro Tago, Mayumi Okamoto, Kiichi Ishiwata, Kenji Ishii. Development of a novel cerebral blood flow PET tracer for diagnosis of dementia with diabetes mellitus. JOURNAL OF NUCLEAR MEDICINE. 2017. 58