Reconstitution of renal vasculature based on its development
Project/Area Number |
15K15332
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Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
Allocation Type | Multi-year Fund |
Research Field |
Kidney internal medicine
|
Research Institution | Kumamoto University |
Principal Investigator |
|
Project Period (FY) |
2015-04-01 – 2017-03-31
|
Project Status |
Completed (Fiscal Year 2016)
|
Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2016: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
|
Keywords | 腎臓発生 / 血管発生 / 血管内皮 |
Outline of Final Research Achievements |
While we previously succeeded in inducing kidney tissues from stem cells, integration of vasculature is necessary for the renal functions.The purpose of this project is to understand the origin and developmental processes of renal vasculature and apply the knowledge to the vascular reconstitution. We first described the development of extra- and intra-renal arteries/veins. We then identified the molecular profiles of renal vasculature. We also transplanted the embryonic mouse kidneys to the host animals to analyze the development of the vasculature.
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Report
(3 results)
Research Products
(2 results)