Cerebral network plasticity revealed by intraoperative cortico-cortical evoked potentials
Project/Area Number |
25861273
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Neurosurgery
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Research Institution | Kyoto University |
Principal Investigator |
Kikuchi Takayuki 京都大学, 医学(系)研究科(研究院), 助教 (40625084)
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Co-Investigator(Renkei-kenkyūsha) |
KUNIEDA Takeharu 京都大学, 大学院医学研究科, 講師 (60609931)
MATSUMOTO Riki 京都大学, 大学院医学研究科, 准教授 (00378754)
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Project Period (FY) |
2013-04-01 – 2016-03-31
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Project Status |
Completed (Fiscal Year 2015)
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Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
|
Keywords | cortical function / cerebral network / evoked potential / functional plasticity / 皮質皮質間誘発電位 / 脳機能ネットワーク |
Outline of Final Research Achievements |
Cortico-cortical evoked potential (CCEP) was reliably recorded during neurosurgical procedure and can trace the function of language connection through dorsal language pathway. We also applied the same method for ventral language pathway and obtained CCEP on temporal cortex. The pre-and postoperative neurophychological testing revealed removal of the lesion adjacent to this pathway had an influence to the semantic processing with a laterality. We also revealed that the function improved in the postoperative course, indicating functional plasticity.
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Report
(4 results)
Research Products
(25 results)
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[Journal Article] Network specific change in white matter integrity in mesial temporal lobe epilepsy.2016
Author(s)
Imamura, H., R. Matsumoto, S. Takaya, T. Nakagawa, A. Shimotake, T. Kikuchi, N. Sawamoto, T. Kunieda, N. Mikuni, S. Miyamoto, H. Fukuyama, R. Takahashi and A. Ikeda
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Journal Title
Epilepsy Research
Volume: 120
Pages: 65-72
DOI
NAID
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
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[Journal Article] Different Mode of Afferents Determines the Frequency Range of High Frequency Activities in the Human Brain: Direct Electrocorticographic Comparison between Peripheral Nerve and Direct Cortical Stimulation2015
Author(s)
Kobayashi K, Matsumoto R, Matsuhashi M, Usami K, Shimotake A, Kunieda T, Kikuchi T, Mikuni N, Miyamoto S, Fukuyama H, Takahashi R, Ikeda A
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Journal Title
PLoS One
Volume: 10 (6)
Issue: 6
Pages: e0130461-e0130461
DOI
NAID
Related Report
Peer Reviewed / Open Access
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[Journal Article] Direct Exploration of the Role of the Ventral Anterior Temporal Lobe in Semantic Memory: Cortical Stimulation and Local Field Potential Evidence From Subdural Grid Electrodes2015
Author(s)
Shimotake A, Matsumoto R, Ueno T, Kunieda T, Saito S, Hoffman P, Kikuchi T, Fukuyama H, Miyamoto S, Takahashi R, Ikeda A, Lambon Ralph MA
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Journal Title
Cerebral Cortex
Volume: 印刷中
Issue: 10
Pages: 3802-3817
DOI
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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[Journal Article] Neural correlates of mirth and laughter: A direct electrical cortical stimulation study.2014
Author(s)
Yamao, Y., R. Matsumoto, T. Kunieda, S. Shibata, A. Shimotake, T. Kikuchi, T. Satow, N. Mikuni, H. Fukuyama, A. Ikeda and S. Miyamoto
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Journal Title
Cortex
Volume: -
Pages: 134-40
DOI
NAID
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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[Journal Article] Intraoperative dorsal language network mapping by using single-pulse electrical stimulation.2014
Author(s)
Yamao Y, Matsumoto R, Kunieda T, Arakawa Y, Kobayashi K, Usami K, Shibata S, Kikuchi T, Sawamoto N, Mikuni N, Ikeda A, Fukuyama H, Miyamoto S.
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Journal Title
Hum Brain Mapp
Volume: 印刷中
Issue: 9
Pages: 74-85
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] The modulation of rolandic oscillation induced by digital nerve stimulation and self-paced movement of the finger: A MEG study.2014
Author(s)
Enatsu, R., Nagamine, T., Matsubayashi, J., Maezawa, H., Kikuchi, T., Fukuyama, H., Mikuni, N., Miyamoto, S., & Hashimoto, N.
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Journal Title
Journal of Neurological Sciences
Volume: 337
Issue: 1-2
Pages: 201-211
DOI
Related Report
Peer Reviewed
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[Journal Article] Long-term seizure outcome following resective surgery for epilepsy: to be or not to be completely cured?2013
Author(s)
Kunieda T1, Mikuni N, Shibata S, Inano R, Yamao Y, Kikuchi T, Matsumoto R, Takahashi J, Ikeda A, Fukuyama H, Miyamoto S.
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Journal Title
Neurologia Medico-Chirurgica
Volume: 53
Pages: 805-13
Related Report
Peer Reviewed
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[Presentation] Intraoperative language network monitoring by means of cortico-cortical evoked potentials
Author(s)
Yukihiro Yamao, Riki Matsumoto, Takeharu Kunieda, Yoshiki Arakawa, Katsuya Kobayashi, Kiyohide Usami, Sumiya Shibata, Takayuki Kikuchi, Nobukatsu Sawamoto, Nobuhiro Mikuni, Akio Ikeda, Hidenao Fukuyama and Susumu Miyamoto
Organizer
30th International Congress of Clinical Neurophysiology
Place of Presentation
Berlin
Related Report
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[Presentation] Intraoperative Supplementary Motor Area (SMA) Monitoring for Medial Frontal Lesions
Author(s)
Sumiya Shibata 1), Takeharu Kunieda 1), Riki Matsumoto 2), Yukihiro Yamao 1), Rika Inano 1),, Takayuki Kikuchi 1), Yoshiki Arakawa 1), Toshiya Sugino 1), Takeshi Funaki 1), Takafumi Mitsuhara 1), Masaomi Koyanagi 1), Kazumichi Yoshida 1), Yasushi Takagi 1), Jun Takahashi 1), Akio Ikeda 2), Susumu Miyamoto 1)
Organizer
第72回日本脳神経外科学会総会
Place of Presentation
横浜
Related Report
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[Presentation] Intraoperative Supplementary Motor Area (SMA) Monitoring for Medial Frontal Lesions
Author(s)
Sumiya Shibata 1), Takeharu Kunieda 1), Riki Matsumoto 2), Yukihiro Yamao 1), Rika Inano 1),, Takayuki Kikuchi 1), Yoshiki Arakawa 1), Toshiya Sugino 1), Takeshi Funaki 1), Takafumi Mitsuhara 1), Masaomi Koyanagi 1), Kazumichi Yoshida 1), Yasushi Takagi 1), Jun Takahashi 1), Akio Ikeda 2), Susumu Miyamoto 1)
Organizer
第37回 日本てんかん外科学会
Place of Presentation
大阪
Related Report
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