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YUBISUI Toshitsugu  指吸 俊次

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指吸 俊次

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Researcher Number 00019564
Other IDs
Affiliation (based on the past Project Information) *help 1997 – 1998: 高知大学, 理学部, 教授
1994 – 1995: 高知大学, 理学部, 教授
1986 – 1993: 大分医科大学, 医学部, 助教授
Review Section/Research Field
Principal Investigator
General medical chemistry / Functional biochemistry
Except Principal Investigator
Pathological medical chemistry / Developmental biology / Respiratory organ internal medicine / 物質生物化学 / General medical chemistry
Keywords
Principal Investigator
変異酵素 / 硝酸還元酵素 / cDNAクローニング / シトクロムb_5 / NADH-シトクロムb_5還元酵素 / 遺伝性メトヘモグロビン血症 / Mutant enzyme / Ser-127->Pro mutant / Point mutation / Hereditary deficiency … More / Gene structure / NADH-cytochrome b_5 reductase / 部位特異的突然変異 / cDNA発現 / エクソン / cDNA / 大腸菌内発現 / シトクロムb_5還元酵素欠損 / 遺伝子構造解析 / Ser→Pro突然変異 / 点突然変異 / 遺伝性疾患 / 遺伝子構造 / シトクロムb_5還元酵素 / recombinant protein / co-expression / tunicate / gene expression / cDNA cloning / Cytochrome b5 / タンパク質発現 / 機能解析 / 発現調節 / 遺伝子 / ホルモン代謝 / 薬物代謝 / シトクロムP450 / リコンビナントb5 / シトクロムb5遺伝子 / Cytochrome P450 reductase / Mutagenesis / Crystal structure / Nitrate reductase / Cytochrome b5 reductase / Nucleotide-binding motif / ミノ酸置換 / NADH-シトクロムb5還元酵素 / モチーフ / ヌクレオチド / シトクロムP450還元酵素 / アミノ酸置換 / 結晶構造 / シトクロムb5還元酵素 / ヌクレオチド結合モチーフ / LOCALIZATION IN BRAIN / FUNCTIONS IN BRAIN / cDNA CLONING / CYTOCHROME b_5 / cDNAクロ-ニング / 脳での局在部位 / 脳における機能 / 遺伝性メトヘモクロビン血症 / 血液細胞型 / 全身型 / 赤血球型 / NADHーシトクロムb_5還元酵素 … More
Except Principal Investigator
極長鎖脂肪酸 / ANAE-1 / 脂肪酸縮合 / 脂肪酸伸長 / 脂肪酸伸長反応 / Redio-liquid chromatography / NADH-cytochrome b_5 reductase / Arachidonoyl-CoA / Monoclonal antibody Arachidyl-CoA / Very-long-chain fatty acid elongation / Fatty acid elogation / SH基修飾剤 / 脂肪膜の相分離 / 極長鎖脂肪酸伸長 / ミクロソーム / 体外免疫法 / チトクロム【b_5】 / 副腎白質ジストロフィー症 / ラジオ液体クロマトグラフィー / NADH-シトクロムb_5還元酵素 / アラキドン酸-CoA / アラキジン酸-CoA / モノクローナル抗体 / 極長鎖脂肪酸伸長反応 / 長鎖脂肪酸伸長反応 / dedifferentiation / cell proliferation / retinoic acid / serine protease / aminopeptidase / multipotency / asexual reproduction / tunicate / trefoilモチーフ / アミノペプチターゼ / 分化誘導 / 細胞増殖因子 / リコンビナントタンパク質 / モザイクタンパク質 / kringle / 出芽 / 脱分化 / 細胞増殖 / レチノイン酸 / セリンプロテアーゼ / アミノペプチダーゼ / 多能性細胞 / 無性生殖 / ホヤ / epitherioid cell granuloma / MIF / マクロフアージ遊走阻止活性 / 類上皮細胞肉芽腫 / マクロファージ遊走阻止 / ANAE-I / Acyl-CoA Synthetase / Calcium / Condensation / Fatty Acid Elongation / Microsomes / Oligodendroglia / Cytoskeleton / Long-Chain-Fatty Acid / 細胞培養 / パ-コ-ル法 / 脳ミクロソ-ム / サイクリックAMP / コルヒチン / アシルCoA合成酵素 / カルシュウム / 縮合活性 / 脂肪酸伸長活性 / ミクロソ-ム / オリゴデンドログリア / 細胞骨格 / 長鎖脂肪酸 / hypertension / 2-ketoacyl-CoA reductase / site directed mutagenesis / cytochrome b_5 reductase / monoenoic fatty acid / fatty acid condensation / myelination / fatty acid elongation / 牛血清アルブミン / ブタ動脈壁細胞 / 脂肪酸水酸化 / 滑面小胞体 / 粗面小胞体 / セレブロシド / 白血球 / 副腎白質ジストロフィ- / thiolesterase / CHAPSO / モノ不飽和脂肪酸 / 動脈硬化 / 2ーケトアシルCoA還元酵素 / NADHーシトクロムb_5還元酵素 / 高血圧 / 2-ケトアシルCoA還元酵素 / 部位特異的変異 / シトクロムb_5還元酵素 / モノエン脂肪酸 / 脂肪酸縮合酵素 / ミエリン形成 / 脂肪酸伸長酵素 / リグノセリン酸水酸化反応 / 赤血球型と知能障害型 / アミノ酸配列 / 全翻訳配列 / NADH-チトクロム【b_5】還元酵素 / 遺伝性メトヘモグロビン血症 Less
  • Research Projects

    (13 results)
  • Co-Researchers

    (19 People)
  •  Regulation of gene expression and function of cytochrome b5Principal Investigator

    • Principal Investigator
      YUBISUI Toshitsugu
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Functional biochemistry
    • Research Institution
      Kochi University
  •  Structure and function of dedifferentiation factors with proteolytic and mitogenic activities in budding tunicates

    • Principal Investigator
      KAWAMURA Kazuo
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Developmental biology
    • Research Institution
      Kochi University
  •  Structure of the New Motifs for Nucleotide-bindingPrincipal Investigator

    • Principal Investigator
      YUBISUI Toshitsugu
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Kochi University
  •  遺伝性メトヘモグロビン血症の発症機構の解明Principal Investigator

    • Principal Investigator
      指吸 俊次
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      大分医科大学
  •  Biological activity of the ANAE-1 derived from the granuloma macrophage

    • Principal Investigator
      TSUDA Tomiyasu
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Oita Medical University
  •  遺伝性メトヘモグロビン血症の発症機構の解明Principal Investigator

    • Principal Investigator
      指吸 俊次
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      大分医科大学
  •  遺伝性メトヘモグロビン血症の発症機構の解明Principal Investigator

    • Principal Investigator
      指吸 俊次
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      大分医科大学
  •  IDENTIFICATION OF NEW SPECIES OF BRAIN-SPECIFIC CYTOCHROME b_5Principal Investigator

    • Principal Investigator
      YUBISUI Toshitsugu
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      OITA MEDICAL UNIVERSITY
  •  Metabolic Regulation in Fatty Acid Elongation System

    • Principal Investigator
      TAKESHITA Masazumi
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      OITA MEDICAL UNIVERSITY
  •  Interaction between brain microsomal long-chain fatty acid synthesis systems and cytoskeletons.

    • Principal Investigator
      SAKAI KUMIKO, 吉田 敏
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      物質生物化学
    • Research Institution
      Oita Medical University
  •  Gene structure of NADH-cytochrome b_5 reductase and regulation of expressionPrincipal Investigator

    • Principal Investigator
      YUBISUI Toshitsugu
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Medical College of Oita
  •  遺伝性メトヘモグロビン血症の赤血球型と知能障害型の病態に関する研究

    • Principal Investigator
      竹下 正純
    • Project Period (FY)
      1985 – 1986
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      大分医科大学
  •  Analysis of Brain Fatty Acid Metabolism and its Abnormality by Application of Monoclonal Antibody

    • Principal Investigator
      TAKESHITA Masazumi
    • Project Period (FY)
      1985 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Nedical College of Oita
  • 1.  TAKESHITA Masazumi (50019551)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 0 results
  • 2.  SHIRABE Komei (50179058)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 3.  YOSHIDA Satoshi (50158440)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 4.  TAMURA Minoru (00128349)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  キャンベル ウイルバーH
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  SAKAI KUMIKO (60225753)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  TSUDA Tomiyasu (80040567)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  MIYAZAKI Eishi (00264333)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  KAWAMURA Kazuo (30136361)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  ポーター トッド D.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  キャンベル ウイルバー
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  CAMPBELL Wilbur h
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  PORTER Todd d
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  ポーター トッドD.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  ステッグルス アランW.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  PORTER Todd D.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  CAMPBELL Wilbur H.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  STEGGLES Alen W.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  キャンベル ウイルパーH
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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