TOKUMURA Akira 徳村彰

Researcher Number	00035560
Other IDs
Affiliation (based on the past Project Information) *help	2014 – 2016: 安田女子大学, 薬学部, 教授 2014: 徳島大学, 大学院ヘルスバイオサイエンス研究部, 教授 2011 – 2013: 徳島大学, ヘルスバイオサイエンス研究部, 教授 2009 – 2011: 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 教授 2006: The University of Tokushima, Graduate School, Institute of Health Sciences, Associate professor, 大学院ヘルスバイオサイエンス研究部, 助教授 … More 2004 – 2005: 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 助教授 2001 – 2002: 徳島大学, 薬学部, 助教授 1998 – 1999: 徳島大学, 薬学部, 助教授 1995 – 1996: 徳島大学, 薬学部, 助教授 1992: 徳島大学, 薬学部, 助教授 1992: The University of Tokushima Faculty of Pharmaceutical Sciences Institute for Natural Sources Associate Professor, 薬学部附属医薬資源教育研究センター, 助教授 1991: 徳島大学, 薬学部, 助手 1987 – 1988: 徳島大学, 薬学部, 助手 Less
Review Section/Research Field	Principal Investigator Biological pharmacy / 応用生物化学・栄養化学 / Environmental pharmacy / Biological pharmacy Except Principal Investigator Food science / Applied health science
Keywords	Principal Investigator リゾホスホリパーゼD / リゾホスファチジン酸 / リゾホスファチジルコリン / lysophospholipase D / lysophosphatidic acid / 動脈硬化 / atherosclerosis / 血小板活性化因子 / lysophosphatidylcholine / oxidized phospholipid … More / 高コレステロール血症 / 酸化リン脂質 / 高血圧自然発症ラット / リゾリン脂質 / Metabolism of PAF / Translocation of phospholipids / Vitamin E deficiency / Acetylhydrolase / Acetyltransferase / Platelet-activating factor / ラット好中球 / 血小板活性化因子(PAF) / ウサギ血小板 / アルキルアシルグリセロホスホコリン / PAFの代謝 / リン脂質の膜内移行 / ビタミンE欠乏 / アセチルヒドラーゼ / アセチルトランスフェラーゼ / cancer metastasis / platelet activating factor / lysophospholipid / oxidative stress / 脂質メディエーター / 動脈更硬化 / 酸化変性リン脂質 / 血小板活性因子 / 血管内皮細胞 / 鉄イオン / キシレノールオレンジ / ホスファチジルコリン / 脂質過酸化物 / 癌転移 / 酸化ストレス / hypercholesterolemia / hyperlipidemia / serum / nucleotide phosphodiesterase / 高コレステロール食 / ウサギ血清 / リゾホスファチジツコリン / 増殖因子 / ヌクレオケドホスホジエステラーゼ / 高脂血症 / 血清 / ヌクレオチドホスホジエステラーゼ / hypercholesteromia / lipid peroxidation / plateletactivating factor / リゾホステァチジルコリン / リゾホステァチジン酸 / 血漿脂質 / リポキシゲナーゼ / 酸化リポタンパク / リゾホスファチジルコン / 脂質過酸化 / spontaneously hypertensive rat / vascular smooth muscle / cell migration / cell proliferation / DNA synthesis / 血管平滑筋細胞 / 細胞遊走 / 細胞増殖 / DNA合成 / リゾホスホリパーゼ D / Contraction of aorta / Plasma phospholipid / Spontaneously hypertensive rat / Hypertension / Lysophospholipase D / Lysophosphatidylcholine / Lysophosphatidic acid / 自然発生高血圧ラット / リゾホスホリパ-ゼD / 血管平滑筋収縮 / 大動脈片 / 血圧 / 血管片の収縮 / 血漿リン脂質 / 高血圧 / 歯肉 / ホスホリパーゼ / ドライマウス / 歯肉上皮 / リゾホスホリパーゼC / リゾリン脂質メディエーター / 骨芽細胞 / 歯周病 / 口腔粘膜 / 歯肉上皮細胞 / 歯肉溝浸出液 … More Except Principal Investigator リン脂質 / リゾホスファチジン酸 / 脂質メディエーター / 抗消化性潰瘍 / 消化管 / ホスファチジン酸 / 生活習慣病 / 脂質生化学 / N-アシルエタノールアミン / 肥満 / ホスホリパーゼ / 酵素 / カルシウム / cyclooxygenase 2 / prostaglandin E2 / apoptosis / ceramide-1-phosphate / anti-ulcer / phosphatidic acid / lysophosphatidic acid / phospholipid / 植物 / 消化管粘膜 / アスピリン潰瘍 / ムチン / 表層粘液細胞 / 胃粘膜 / 粘液分泌 / 植物性食品 / 細胞遊走 / 粘膜上皮組織 / リゾボスファチジン酸 / 創傷治癒 / 粘膜上皮細胞 / セラミド1-リン酸 / 抗潰瘍 / 消化管粘膜保護 / 食品 Less

Novel mechanisms for the biosynthesis of the lipid mediator regulating appetite and obesity
- Principal Investigator
  
  Tsuboi Kazuhito
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied health science
- Research Institution
  Kagawa University
Effect of plant phospholipid on integrity of gastrointestinal mucosa
- Principal Investigator
  
  TANAKA Tamotsu
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Food science
- Research Institution
  The University of Tokushima
Lysophosphatidic acid production by novel membrane-bound lysophospholipase D and protection of oral mucosaPrincipal Investigator
- Principal Investigator
  
  TOKUMURA Akira
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokushima
Studies on gastrointestinal mucosa-maintaining factors produced during digestion of foods
- Principal Investigator
  
  TANAKA Tamotsu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Food science
- Research Institution
  The University of Tokushima
Marignancy of cell-proliferative diseases by unusual production of phospholipid mediators in response to oxidative stressPrincipal Investigator
- Principal Investigator
  
  TOKUMURA Akira
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Environmental pharmacy
- Research Institution
  The University of Tokushima
Progression of atherosclerotic lesions induced by excess production of lysophosphatidic acid, a growth factor in serumPrincipal Investigator
- Principal Investigator
  
  TOKUMURA Akira
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokushima
Investigation on the involvment of oxidized phospholipids and lysophospholipids in the pathogenesis of atherosclerosisPrincipal Investigator
- Principal Investigator
  
  TOKUMURA Akira
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokushima
Proliferation and migration of vascular smooth muscle cell induced by novel physiologically active phospholipidPrincipal Investigator
- Principal Investigator
  
  TOKUMURA Akira
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokushima
Lipid mediators in circulation and hypertensionPrincipal Investigator
- Principal Investigator
  
  TOKUMURA Akira
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokushima
PAFの生合成並びに遊離に及ぼす食餌性脂質の効果Principal Investigator
- Principal Investigator
  
  TOKUMURA Akira
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用生物化学・栄養化学
- Research Institution
  The University of Tokushima

All 2016 2015 2014 2013 2012 2011 2010 2009 2007 2006 2004 Other

All Journal Article Presentation

[Journal Article] Calcium-dependent generation of N-acylethanolamines and lysophosphatidic acids by glycerophosphodiesterase GDE72016
- Author(s)
  Rahman, I.A.S., Tsuboi, K., Hussain, Z., Yamashita, R., Okamoto, Y., Uyama, T., Yamazaki, N., Tanaka, T., Tokumura, A., and Ueda, N.
- Journal Title
  
  Biochim. Biophys. Acta-Mol. Cell Biol. Lipids
  
  Volume: 1861 Issue: 12 Pages: 1881-1892
- DOI
  10.1016/j.bbalip.2016.09.008
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26350894, KAKENHI-PROJECT-15K08278, KAKENHI-PROJECT-16K08589
[Journal Article] Glycerophosphodiesterase GDE4 as a novel lysophospholipase D: a possible involvement in bioactive N-acylethanolamine biosynthesis2015
- Author(s)
  Kazuhito Tsuboi, et al.
- Journal Title
  
  Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids
  
  Volume: 1851 Issue: 5 Pages: 537-548
- DOI
  10.1016/j.bbalip.2015.01.002
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590355, KAKENHI-PROJECT-25460370, KAKENHI-PROJECT-26350894
[Journal Article] Type 2 lysophosphatidic acid receptor in gastric surface mucous cells: Possible implication of prostaglandin E2 production2014
- Author(s)
  Tamotsu Tanaka, Mayumi Ohmoto, Katsuya Morito, Hiroki Kondo, Mai Urikura, Kiyoshi Satouchi and Akira Tokumura
- Journal Title
  
  BioFactors
  
  Volume: 40 Issue: 3 Pages: 355-361
- DOI
  10.1002/biof.1147
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24580185
[Journal Article] Metabolic conversion of C20 polymethylene-interrupted polyunsaturated fatty acids to essential fatty acids2014
- Author(s)
  Tamotsu Tanaka, Sachika Uozumi, Katsuya Morito, Takashi Osumi and Akira Tokumura
- Journal Title
  
  Lipids
  
  Volume: 49 Pages: 423-429
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24580185
[Journal Article] Extracellular metabolism-dependent uptake of lysolipids through cultured monolayer of differentiated Caco-2 cells2014
- Author(s)
  Maiko Inaba, Kaeko Murota, Miki Nikawadori, Erika Kishino, Risa Matsuda, Mika Takagi, Takeshi Ohkubo, Tamotsu Tanaka, Junji Terao and Akira Tokumura
- Journal Title
  
  Biochim. Biophys. Acta
  
  Volume: 1841 Pages: 121-131
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24580185
[Journal Article] Extracellular metabolism-dependent uptake of lysolipids through cultured monolayer of differentiated Caco-2 cells2014
- Author(s)
  M. Inaba, K. Murota, M. Nikawadori, E. Kishino, R. Matsuda, M. Takagi, T. Ohkubo, T. Tanaka, J. Terao, & A. Tokumura
- Journal Title
  
  Biochim. Biophys. Acta
  
  Volume: in press Issue: 1 Pages: 121-131
- DOI
  10.1016/j.bbalip.2013.10.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24580185
[Journal Article] Metabolic conversion of C20 polymethylene-interrupted polyunsaturated fatty acids to essential fatty acids2014
- Author(s)
  T. Tanaka, S. Uozumi, K. Morito, T. Osumi, A. Tokumura
- Journal Title
  
  Lipids
  
  Volume: in press Issue: 5 Pages: 423-429
- DOI
  10.1007/s11745-014-3896-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24580185, KAKENHI-PROJECT-25440053
[Journal Article] Orally administered phosphatidic acids and lysophosphatidic acids ameliorate aspirin-induced stomach mucosal injury in mice2013
- Author(s)
  T. Tanaka, K. Morito, M. Kinoshita, M. Ohmoto, M. Urikura, K. Satouchi & A. Tokumura
- Journal Title
  
  Dig. Dis. Sci.
  
  Volume: 58 Issue: 4 Pages: 950-958
- DOI
  10.1007/s10620-012-2475-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24580185
[Journal Article] Identification of a sphingolipid-specific phospholipase D activity associated with the generation of phytoceramide-1-phosphate in cabbage leaves.2013
- Author(s)
  Tamotsu Tanaka, Takashi Kida , Hiroyuki lmai, Jun-ichi Morishige, Sachika Uozumi, Kiyoshi Satouchi, Minoru Nagano and Akira Tokumura
- Journal Title
  
  The FEBS Journal
  
  Volume: 280 Issue: 16 Pages: 3797-3809
- DOI
  10.1111/febs.12374
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J08349, KAKENHI-PROJECT-24580185
[Journal Article] Quantification of phosphatidic acid in foodstuffs using TLC-imaging technique2012
- Author(s)
  T. Tanaka, A. Kassai, M. Ohmoto, K. Morito, Y. Kashiwada, Y. Takaishi, M. Urikura, J. Morishige, K. Satouchi & A. Tokumura
- Journal Title
  
  J. Agric. Food Chem
  
  Volume: (in press) Issue: 16 Pages: 4156-4161
- DOI
  10.1021/jf300147y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580141, KAKENHI-PROJECT-24580185
[Journal Article] Intragastrically administrered lysophospatidic acid protect against gastric ulcer in rats under water-immersion restraint stress2011
- Author(s)
  M. Adachi, G. Horiuchi, N. Ikematsu, T. Tanaka, J. Terao, K. Satouchi, A. Tokumura Dig.
- Journal Title
  
  Dis. Sci
  
  Volume: 56 Issue: 8 Pages: 2252-2261
- DOI
  10.1007/s10620-011-1595-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580141
[Journal Article] Formation of lysophosphatidic acid, a wound-healing lipid, during digestion ofcabbage leaves2009
- Author(s)
  T. Tanaka, G. Horiuchi, M. Matsuoka, K. Hirano, A. Tokumura, T. Koike & K. Satouchi
- Journal Title
  
  Biosci. Biotech. Biochem
  
  Volume: 73 Pages: 1293-1300
- URL
  http://dx.doi.org/10.1271/bbb.80813
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580141
[Journal Article] Peritoneal fluids from patients with certain gynecologic tumor contain elevated levels of bioactive lysophospholipase D activity2007
- Author(s)
  A.Tokumura et al.
- Journal Title
  
  Life Sciences. 1641-1649
  
  Pages: 80-18
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390034
[Journal Article] Peritoneal fluids from patients with certain gynecologic tumor contain elevated levels of bioactive lysophospholipase D activity2007
- Author(s)
  A.Tokumura et al.
- Journal Title
  
  Life Sciences 80・18
  
  Pages: 1641-1649
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390034
[Journal Article] 細胞外でリゾ脂質メディエーターを産世するホスホジエステラーゼ2006
- Author(s)
  徳村彰
- Journal Title
  
  生化学 78・12
  
  Pages: 1141-1154
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390034
[Journal Article] Phosphodiesterases that extracellularly produce lysolipid mediators2006
- Author(s)
  A.Tokumura
- Journal Title
  
  Seikagaku 78-12
  
  Pages: 1141-1154
- NAID
  10018675562
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390034
[Journal Article] Proinflammatory platelet-activating factor (PAF)-like phospholipids and their pathophysiological significance2004
- Author(s)
  A.Tokumura
- Journal Title
  
  Chem.Phys.Lipids 130・1
  
  Pages: 18-21
- Data Source
  KAKENHI-PROJECT-16390034
[Presentation] A possible involvement of acid ceramidase in the degradation of N-acylethanolamines2016
- Author(s)
  Tsuboi, K., Tai, T., Okamoto, Y., Yamashita, R., Rahman, I.A.S., Uyama, T., Houchi, H., Tanaka, T., Tokumura, A., and Ueda, N.
- Organizer
  26th Annual Symposium of the International Cannabinoid Research Society
- Place of Presentation
  Bukovina, Poland
- Year and Date
  2016-06-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26350894
[Presentation] 酸性セラミダーゼによる細胞内N-アシルエタノールアミンの加水分解2016
- Author(s)
  坪井一人、田井達也、岡本蓉子、山下量平、Iffat Ara Sonia Rahman、宇山　徹、芳地　一、田中　保、徳村　彰、上田夏生
- Organizer
  第58回日本脂質生化学会
- Place of Presentation
  秋田市にぎわい交流館AU（秋田県秋田市）
- Year and Date
  2016-06-10
- Data Source
  KAKENHI-PROJECT-26350894
[Presentation] 口腔粘膜上皮細胞に存在する膜結合型リゾホスホリパーゼD2016
- Author(s)
  松田璃沙、坪井一人、岡本蓉子、山下量平、Iffat Ara Sonia Rahman、日高麻由美、山崎尚志、上田夏生、田中　保、徳村　彰
- Organizer
  第58回日本脂質生化学会
- Place of Presentation
  秋田市にぎわい交流館AU（秋田県秋田市）
- Year and Date
  2016-06-10
- Data Source
  KAKENHI-PROJECT-26350894
[Presentation] GDE7はリゾホスホリパーゼD型酵素としてN-アシルエタノールアミンとLPAを生成する2016
- Author(s)
  坪井一人、Iffat Ara Sonia Rahman、岡本蓉子、宇山　徹、山崎尚志、田中　保、徳村　彰、上田夏生
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-09-27
- Data Source
  KAKENHI-PROJECT-26350894
[Presentation] 脂質メディエーターであるN-アシルエタノールアミンとLPAを生成する新規酵素の解析2016
- Author(s)
  坪井一人、Iffat Ara Sonia Rahman、岡本蓉子、宇山　徹、田中　保、徳村　彰、上田夏生
- Organizer
  日本ビタミン学会第68回大会
- Place of Presentation
  富山国際会議場（富山県富山市）
- Year and Date
  2016-06-18
- Data Source
  KAKENHI-PROJECT-26350894
[Presentation] Glycerophosphodiesterases, GDE4 and GDE7, are novel lysophospholipase D-type enzymes generating N-acylethanolamine and LPA2016
- Author(s)
  Rahman, I.A.S., Tsuboi, K., Okamoto, Y., Uyama, T., Yamazaki, N., Tanaka, T., Tokumura, A., and Ueda, N.
- Organizer
  第57回日本生化学会中国四国支部例会
- Place of Presentation
  高知大学岡豊キャンパス（高知県南国市）
- Year and Date
  2016-05-28
- Data Source
  KAKENHI-PROJECT-26350894
[Presentation] バイオファクターであるN-アシルエタノールアミンとリゾホスファチジン酸(LPA)の新規生合成機構2016
- Author(s)
  坪井一人、Iffat Ara Sonia Rahman、Zahir Hussain、山下量平、岡本蓉子、宇山　徹、田中　保、徳村　彰、上田夏生
- Organizer
  第353回脂溶性ビタミン総合研究委員会
- Place of Presentation
  ホテル伊東ガーデン（静岡県伊東市）
- Year and Date
  2016-12-02
- Data Source
  KAKENHI-PROJECT-26350894
[Presentation] Glycerophosphodiesterase GDE4 is a novel lysophospholipase D generating N-acylethanolamine and LPA2015
- Author(s)
  Tsuboi, K., Okamoto, Y., Rahman, I. A. S., Uyama, T., Inoue, T., Tokumura, A., and Ueda, N.
- Organizer
  6th International conference on phospholipase A2 and lipid mediators
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Year and Date
  2015-02-12
- Data Source
  KAKENHI-PROJECT-26350894
[Presentation] 新規リゾホスホリパーゼD型酵素であるグリセロホスホジエステラーゼGDE4はN-アシルエタノールアミンとLPAの生合成に関与する2015
- Author(s)
  坪井一人，岡本蓉子，Iffat Ara Sonia Rahman，宇山　徹，徳村　彰，上田夏生
- Organizer
  第57回日本脂質生化学会
- Place of Presentation
  一橋講堂（東京都千代田区）
- Year and Date
  2015-05-28
- Data Source
  KAKENHI-PROJECT-26350894
[Presentation] 穀物におけるホスファチジン酸(PA)含量とPAの抗消化性潰瘍効果2015
- Author(s)
  生駒照, 屋宜亜耶乃, 藤川昂樹, 森戸克弥, 南利夫, 徳村彰, 田中保
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸学院大学（兵庫県神戸市）
- Year and Date
  2015-03-26
- Data Source
  KAKENHI-PROJECT-24580185
[Presentation] 新規リゾホスホリパーゼD型酵素GDE4によるN-アシルエタノールアミンとLPAの生成2015
- Author(s)
  坪井一人，岡本蓉子，Iffat Ara Sonia Rahman，宇山　徹，藤内武春，徳村　彰，上田夏生
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートピアホテル（兵庫県神戸市）
- Year and Date
  2015-12-04
- Data Source
  KAKENHI-PROJECT-26350894
[Presentation] Glycerophosphodiesterase GDE4 is a novel lysophospholipase D-type enzyme generating N-acylethanolamines2015
- Author(s)
  Tsuboi, K., Okamoto, Y., Rahman, I. A. S., Uyama, T., Tokumura, A., and Ueda, N.
- Organizer
  25th Annual Symposium of the International Cannabinoid Research Society
- Place of Presentation
  Wolfville (Canada)
- Year and Date
  2015-07-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26350894
[Presentation] 消化管上皮細胞に存在する新規膜結合型リゾホスホリパーゼD2015
- Author(s)
  松田璃沙，坪井一人，岡本蓉子，Iffat Ara Sonia Rahman，山崎尚志，上田夏生，田中　保，徳村　彰
- Organizer
  第54回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Place of Presentation
  高知市文化プラザかるぽーと（高知県高知市）
- Year and Date
  2015-10-31
- Data Source
  KAKENHI-PROJECT-26350894
[Presentation] Development of a fluorescence-based assay system for acid ceramidase activity2015
- Author(s)
  Tsuboi, K., Okamoto, Y., Rahman, I. A. S., Uyama, T., Inoue, T., Tokumura, A., and Ueda, N.
- Organizer
  6th International conference on phospholipase A2 and lipid mediators
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Year and Date
  2015-02-11
- Data Source
  KAKENHI-PROJECT-26350894
[Presentation] 新規リゾホスホリパーゼD型酵素GDE4関連代謝経路のLC-MS/MSによる同定2015
- Author(s)
  岡本蓉子，坪井一人，Iffat Ara Sonia Rahman，上田夏生，田中　保，徳村　彰
- Organizer
  第54回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Place of Presentation
  高知市文化プラザかるぽーと（高知県高知市）
- Year and Date
  2015-10-31
- Data Source
  KAKENHI-PROJECT-26350894
[Presentation] PLA/acyltransferase family proteins are involved in generation of N-acylphosphatidylethanolamine in living cells2015
- Author(s)
  Watanabe, M., Uyama, T., Inoue, M., Okamoto, Y., Shinohara, N., Tsuboi, K., Tokumura, A., and Ueda, N.
- Organizer
  6th International conference on phospholipase A2 and lipid mediators
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Year and Date
  2015-02-11
- Data Source
  KAKENHI-PROJECT-26350894
[Presentation] 歯周病の進行に及ぼす口腔内リゾホスファチジン酸の抑制効果2014
- Author(s)
  橋村慧, 松田璃沙, 稲垣裕司, 松井寛和, 横田美帆, 田中保, 木戸淳一, 永田俊彦, 徳村彰
- Organizer
  第56回　日本脂質生化学会
- Place of Presentation
  近畿大学東大阪キャンパス（大阪府東大阪）
- Year and Date
  2014-06-07
- Data Source
  KAKENHI-PROJECT-24580185
[Presentation] 大豆由来リゾホスファチジン酸の歯周病抑制効果2014
- Author(s)
  橋村慧, 松田璃沙, 稲垣裕司, 松井寛和, 横田美帆, 田中保, 木戸淳一, 永田俊彦, 徳村彰
- Organizer
  日本農芸化学会中四国支部第 40回講演会
- Place of Presentation
  徳島大学（徳島県徳島市）
- Year and Date
  2014-09-27
- Data Source
  KAKENHI-PROJECT-24580185
[Presentation] LRATに相同性を示す新規リン脂質代謝酵素PLA/AT-1の機能解析2014
- Author(s)
  宇山　徹，井上愛美，岡本蓉子，Iffat Ara Sonia Rahman，坪井一人，井上智人，徳村　彰，上田夏生
- Organizer
  日本ビタミン学会第66回大会
- Place of Presentation
  姫路商工会議所（兵庫県姫路市）
- Year and Date
  2014-06-13
- Data Source
  KAKENHI-PROJECT-26350894
[Presentation] Peroxisomal dysfunction by PLA/AT family proteins is not related to their NAPE-forming N-acyltransferase activity2014
- Author(s)
  Uyama, T., Inoue, M., Okamoto, Y., Shinohara, N., Tai, T., Watanabe, M., Rahman, I.A.S., Tsuboi, K., Inoue, T., Tokumura, A., and Ueda, N.
- Organizer
  24th Annual Symposium of the International Cannabinoid Research Society
- Place of Presentation
  Baveno (Italy)
- Year and Date
  2014-07-01
- Data Source
  KAKENHI-PROJECT-26350894
[Presentation] 歯周病におけるリゾホスファチジン酸の役割2014
- Author(s)
  橋村慧, 松田璃沙, 稲垣裕司, 松井寛和, 横田美帆, 田中保, 木戸淳一, 永田俊彦, 徳村彰
- Organizer
  第53回　日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Place of Presentation
  広島国際会議場（広島県広島市）
- Year and Date
  2014-11-09
- Data Source
  KAKENHI-PROJECT-24580185
[Presentation] 種々のセラミド-1-リン酸の生理活性2014
- Author(s)
  田畑優美香, 山下量平, 伊賀永里奈, 喜田孝史, 安藤千恵, 徳村彰, 田中保
- Organizer
  第53回　日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Place of Presentation
  広島国際会議場（広島県広島市）
- Year and Date
  2014-11-09
- Data Source
  KAKENHI-PROJECT-24580185
[Presentation] リン脂質メディエーター代謝異常と生活習慣病2013
- Author(s)
  徳村彰
- Organizer
  日本脂質栄養学会第22回大会特別講演
- Place of Presentation
  高知会館(高知県)
- Year and Date
  2013-09-12
- Data Source
  KAKENHI-PROJECT-23590079
[Presentation] Generation of lysolipid mediators by membrane-bound lysophospholipase C and D in the surface of mammalian cells2013
- Author(s)
  Akira Tokumura
- Organizer
  FASEB Summer Research Conference on Lysophospholipid Mediators
- Place of Presentation
  Niseko (Hokkaido)
- Year and Date
  2013-08-12
- Invited
- Data Source
  KAKENHI-PROJECT-23590079
[Presentation] キャベツ葉中に見出されたフィトセラミド-1-リン酸の生合成経路と生理作用2011
- Author(s)
  田中保, 喜田孝史, 盛重純一, 安藤千恵, 山下量平、里内清, 今井博之, 長野稔, 西迫寛隆, 川添和義, 徳村彰
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都(京都国際会館)
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-21580141
[Presentation] 種々の食材中の創傷治癒性リン脂質含量2011
- Author(s)
  葛西彩香, 木下正文, 足立美佳, 盛重純一, 瓜倉真衣, 里内清, 柏田良樹, 今林潔, 高石喜久, 田中保, 徳村彰
- Organizer
  日本農芸化学会中四国支部第29回講演会
- Place of Presentation
  徳島・徳島大学薬学部
- Year and Date
  2011-01-22
- Data Source
  KAKENHI-PROJECT-21580141
[Presentation] Formation of lysophosphatidic acid, a wound-healing lipid, during digestion of cabbage leaves2010
- Author(s)
  Tamotsu Tanaka, Jun-ichi Morishige, Hiroki Kondo, Masafumi Kinoshita, Mika Adachi, Mai Urikura, Kiyoshi Satouchi, Akira Tokumura
- Organizer
  Keystone Symposia, Bioactive lipis : Biochemistry and Diseases
- Place of Presentation
  京都(ウエスティン都ホテル京都)
- Year and Date
  2010-06-09
- Data Source
  KAKENHI-PROJECT-21580141
[Presentation] Generation of lysolipid mediators by membrane-bound lysophospholipase C and D in the surface of mammalian cells
- Author(s)
  徳村　彰
- Organizer
  FASEB Summer Research Conference on Lysophospholipid Mediators
- Place of Presentation
  ヒルトンニセコビレッジ（北海道）
- Invited
- Data Source
  KAKENHI-PROJECT-23590079
[Presentation] アブラナ科植物に見出されたグリコシルイノシトールホスホセラミド特異的ホスホリパーゼD
- Author(s)
  田中保、喜田孝史、今井博之、盛重純一、山下量平、松岡久嗣、魚住幸加、里内清、長野稔、徳村彰
- Organizer
  第55回　日本脂質生化学会
- Place of Presentation
  ホテル松島大観荘（宮城県）
- Data Source
  KAKENHI-PROJECT-24580185
[Presentation] リゾホスファチジン酸による胃粘膜保護のメカニズム
- Author(s)
  森戸克弥, 大本真弓, 生駒照, 木下正文, 近藤宏樹, 瓜倉真衣, 里内清, 田中保, 徳村彰
- Organizer
  第86回　日本生化学会大会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-24580185
[Presentation] リン脂質メディエーター代謝異常と生活習慣病
- Author(s)
  徳村　彰
- Organizer
  日本脂質栄養学会第22回大会
- Place of Presentation
  高知会館（高知県）
- Invited
- Data Source
  KAKENHI-PROJECT-23590079
[Presentation] Identification of a sphingolipid-specific phospholipase D activity associated with the generation of phytoceramide-1-phosphate in cabbage leaves
- Author(s)
  Tamotsu Tanaka, Takashi Kida, Hiroyuki Imai, Jun-ichi Morishige, Ryouhei Yamashita, Hisatsugu Matsuoka, Sachika Uozumi, Kiyoshi Satouchi, Minoru Nagano, and Akira Tokumura
- Organizer
  2013 FASEB Summer Research Conference, Lysophospholipid and other related mediators –From Bench to Clinic-
- Place of Presentation
  ヒルトンニセコビレッジ（北海道）
- Data Source
  KAKENHI-PROJECT-24580185

1. TANAKA Tamotsu (90258301)

# of Collaborated Projects: 3 results

# of Collaborated Products: 20 results
2. Tsuboi Kazuhito (80346642)

# of Collaborated Projects: 1 results

# of Collaborated Products: 19 results
3. UEDA Natsuo (20193807)

# of Collaborated Projects: 1 results

# of Collaborated Products: 18 results
4. FUKUZAWA Kenji (90035551)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. YAMANO Shuji (30166772)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 宇山徹 (30457337)

# of Collaborated Projects: 1 results

# of Collaborated Products: 15 results

TOKUMURA Akira 徳村 彰

Research Projects

Research Products

Co-Researchers

Novel mechanisms for the biosynthesis of the lipid mediator regulating appetite and obesity

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Effect of plant phospholipid on integrity of gastrointestinal mucosa

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Lysophosphatidic acid production by novel membrane-bound lysophospholipase D and protection of oral mucosaPrincipal Investigator

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Studies on gastrointestinal mucosa-maintaining factors produced during digestion of foods

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Marignancy of cell-proliferative diseases by unusual production of phospholipid mediators in response to oxidative stressPrincipal Investigator

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Progression of atherosclerotic lesions induced by excess production of lysophosphatidic acid, a growth factor in serumPrincipal Investigator

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Investigation on the involvment of oxidized phospholipids and lysophospholipids in the pathogenesis of atherosclerosisPrincipal Investigator

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Proliferation and migration of vascular smooth muscle cell induced by novel physiologically active phospholipidPrincipal Investigator

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Lipid mediators in circulation and hypertensionPrincipal Investigator

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PAFの生合成並びに遊離に及ぼす食餌性脂質の効果Principal Investigator

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[Journal Article] Calcium-dependent generation of N-acylethanolamines and lysophosphatidic acids by glycerophosphodiesterase GDE72016

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[Journal Article] Glycerophosphodiesterase GDE4 as a novel lysophospholipase D: a possible involvement in bioactive N-acylethanolamine biosynthesis2015

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[Journal Article] Type 2 lysophosphatidic acid receptor in gastric surface mucous cells: Possible implication of prostaglandin E2 production2014

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[Journal Article] Metabolic conversion of C20 polymethylene-interrupted polyunsaturated fatty acids to essential fatty acids2014

TOKUMURA Akira 徳村彰