HIDAKA Kazuo 日高和夫

Researcher Number	00069064
Other IDs
Affiliation (based on the past Project Information) *help	2009 – 2010: 川崎医科大学, 医学部, 准教授 1996 – 2008: 川崎医科大学, 医学部, 講師
Review Section/Research Field	Except Principal Investigator Legal medicine / Legal medicine / Applied health science
Keywords	Except Principal Investigator パラコート / Paraquat / RT-PCR / 遺伝子発現 / cDNA array / Cytokine / 酸化ストレス / 中毒 / Toxicology / Real-time PCR … More / Real time PCR / Free radical / Differential display / gene expression / Oxidative stress / ラット / differential display / 肺線維化 / 活性酸素 / 一酸化窒素 / 骨形態計測 / マウス / toxicology / グルココルチコイドレセプター / 覚醒剤 / 水浸拘束ストレス / 覚せい剤 / ストレス / Animal model / Immunohistochemistry / Lung fibrosis / Oxidative Stress / real-time PCR / Gene expression / Metallothionein / Heme oxigenase / Masson's Trichrome染色 / fibroblast / 肺線維化モデル / 初期マーカー / マウスモデル / 動物モデル / 免疫組織学 / realtime PCR / Pulmonary injury / Lpin2 / TAFIIB / Clara cell / free radical / superoxide / 肺障害 / Superoxide / Glutathione / Nitric oxide (NO) / Pulmonary fibrosis / 膜脂質過酸化 / Peroxynitrite / 中毒機序 / ラット組織 / A549細胞 / 脂質過酸化 / 中毒学 / グルタチオンレベル / ディファレンシャルディスプレー / mRNA / グルタチオン / 肺線維化現象 / NO Synthase / Nitric Oxide (NO) / Acute Poisoning / 転写レベル / インターロイキン / 急性中毒 / 細胞毒性 / 遺伝子多型 / Heat shock protein Hsp / 心筋毒性 / c-Fos / 神経細胞 / 大腿骨密度 / 生理活性物質 / 骨代謝マーカー / 骨代謝 / ビタミンK2 / 老化促進マウス / 老化 / 加齢 / グルココルチコイドレセプター多型 / サイトカインレベル / IL-6 / 胃粘膜障害 / 多型 / 遺伝子 / サイトカイン Less

Maintenance of bone mineral density in Senescence Accelerated MiceP6 (SAMP6)
- Principal Investigator
  
  KATSUYAMA Hironobu
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied health science
- Research Institution
  Kawasaki Medical School
Effect of stress on methamphetamine intoxication- involvement of stress protein
- Principal Investigator
  
  TOMITA Masafumi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Legal medicine
- Research Institution
  Kawasaki Medical School
Changes in blood cytokine levels under stress conditions and their application to forensic diagnosis.
- Principal Investigator
  
  TOMITA Masafumi
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Legal medicine
- Research Institution
  Kawasaki Medical School
Investigation of the mechanism of paraquat toxicity -Identification of the genes which are breakthrough for the toxicity-
- Principal Investigator
  
  TOMITA Masafumi
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Legal medicine
- Research Institution
  Kawasaki Medical School
Identification and their function of paraquat-induced unknown genes in rat lungs.
- Principal Investigator
  
  TOMITA Masafumi
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Legal medicine
- Research Institution
  Kawasaki Medical School
A breakthrough in paraquat-induced pulmonary fibrosis
- Principal Investigator
  
  TOMITA Masafumi
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Legal medicine
- Research Institution
  KAWASAKI MEDICAL SCHOOL
The contribution of nitric oxide to the paraquat-induced cell injury.
- Principal Investigator
  
  TOMITA Masafumi
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Legal medicine
- Research Institution
  KAWASAKI MEDICAL SCHOOL

All 2011 2010 2009 2008 2006 2005 2004

All Journal Article Presentation Book

[Book] DNA多型2009
- Author(s)
  勝山博信, 伏見滋子, 富田正文, 奥山敏子, 日高和夫, 渡辺洋子, 為近美栄
- Publisher
  東洋書店
- Data Source
  KAKENHI-PROJECT-19590684
[Journal Article] Water-restraint stress enhances methamphetamine-induced cardiotoxicity2011
- Author(s)
  Tomita M, Katsuyama H, Watanabe Y, Hidaka K, Yoshitome K, Miyaishi S, Ishikawa T, Shinone K
- Journal Title
  
  Chemico-Biol Interact
  
  Volume: 190 Issue: 1 Pages: 54-61
- DOI
  10.1016/j.cbi.2011.01.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790612, KAKENHI-PROJECT-22590642, KAKENHI-PROJECT-22590644
[Journal Article] Water-restraint stress enhances methamphetamine-induced cardiotoxicity.2011
- Author(s)
  Tomita M, Katsuyama H, Watanabe Y, Hidaka K, Yoshitome K, Miyaishi S, Ishikawa T, Shinone K, Nata M.
- Journal Title
  
  Chemico-Biological Interactions
  
  Volume: 190 Pages: 54-61
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500684
[Journal Article] The effect of CAG repeat polymorphism in the glucocorticoid receptor on stress responses of mice exposed to waterimmersion restraint stress.2010
- Author(s)
  Tomita M, Katsuyama H, Okuyama T, Watanabe Y, Hidaka K, Otsuki T, Nata M
- Journal Title
  
  Int. J. Mol. Med. 25(3)
  
  Pages: 415-420
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590684
[Journal Article] ELISA法による尿中8-OHdG測定-Ureaseおよびethanol沈殿処理の検討2010
- Author(s)
  渡辺洋子,富田正文,奥山敏子,勝山博信,日高和夫
- Journal Title
  
  川崎医学会誌
  
  Volume: 36 Pages: 73-78
- NAID
  110007990384
- Data Source
  KAKENHI-PROJECT-22590644
[Journal Article] Methamphetamine protects against stress-induced gastric mucosal lesions in mice.2009
- Author(s)
  Tomita M, Okuyama T, Katsuyama H, Watanabe Y, Hidaka K, et. al. (9人)
- Journal Title
  
  Legal Med. (Tokyo) 11(s1)
- NAID
  10027263439
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590684
[Journal Article] Association between serotonin transporter gene polymorphisms and depressed mood caused by job stress in Japanese workers.2008
- Author(s)
  Katsuyama H, Tomita M, Hidaka K, Watanabe Y, et. al. (10人:2番目)
- Journal Title
  
  Int. J. Mol. Med. 21(4)
  
  Pages: 499-505
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590684
[Journal Article] Gene expression in rat lungs during early response to paraquat-induced oxidative stress.2006
- Author(s)
  Tomita M, Okuyama T, Katsuyama H, Hidaka K et al.
- Journal Title
  
  Int. J. Mol. Med. 17
  
  Pages: 37-44
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590552
[Journal Article] Changes in gene expression level for defense system enzymes against oxidative stress and glutathione level in rat administered paraquat.2005
- Author(s)
  Tomita M, Katsuyama H, Okuyam T, Hidaka K, Minatogawa Y
- Journal Title
  
  Int. J. Mol. Med. 15
  
  Pages: 689-693
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590552
[Journal Article] Changes in gene expression level for defense system enzymes against oxidative stress and glutathione level in rat administered paraquat.2005
- Author(s)
  Tomita M, Katsuyama H, Okuyama T, Hidaka K, Minatogawa Y
- Journal Title
  
  Int. J. Mol. Med. 15
  
  Pages: 689-693
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590552
[Journal Article] Early differential gene expression of rat lung after exposure to paraquat.2004
- Author(s)
  Tomita M, Okuyama T, Hidaka K, Ishikawa T, Adachi J, Nohno T
- Journal Title
  
  Free Rad. Res. 38・8
  
  Pages: 821-829
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590552
[Journal Article] Early differential gene expression of rat lung after exposure to paraquat.2004
- Author(s)
  Tomita M, Okuyama T, Hidaka K, Ishikawa T, Adachi J, Nohno T
- Journal Title
  
  Free Rad. Res. 38(8)
  
  Pages: 821-829
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590552
[Presentation] マウス尿中8-OHdGに及ぼす拘束ストレス下における覚醒剤の影響とグルココルチコイドレセプター(GR)多型の関与2010
- Author(s)
  渡辺洋子,日高和夫,富田正文,奥山敏子,勝山博信,伏見滋子ら
- Organizer
  日本DNA多型学会
- Place of Presentation
  三島
- Year and Date
  2010-11-18
- Data Source
  KAKENHI-PROJECT-22590644
[Presentation] 覚醒剤の心筋への作用にストレスは影響するのか2010
- Author(s)
  富田正文,奥山敏子,渡辺洋子,日高和夫,伏見滋子,勝山博信
- Organizer
  日本毒性学会
- Place of Presentation
  沖縄
- Year and Date
  2010-06-18
- Data Source
  KAKENHI-PROJECT-22590644
[Presentation] 拘束ストレス下における覚せい剤の心筋への影響〓マウスのグルココルチコイドレセプター(GR)多型の関与2010
- Author(s)
  富田正文,奥山敏子,勝山博信,伏見滋子,日高和夫,渡辺洋子ら
- Organizer
  日本DNA多型学会
- Place of Presentation
  三島
- Year and Date
  2010-11-18
- Data Source
  KAKENHI-PROJECT-22590644

1. TOMITA Masafumi (50113197)

# of Collaborated Projects: 7 results

# of Collaborated Products: 15 results
2. KATSUYAMA Hironobu (00289175)

# of Collaborated Projects: 4 results

# of Collaborated Products: 12 results
3. NISHIMATSU Shin-ichiro (20222185)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. WATANABE Yoko (70135945)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
5. NOHNO Tsutomu (20098619)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
6. ISHIKAWA Tetsuya (90221754)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. OKUYAMA Toshiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. ISHIKAWA Takaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HIDAKA Kazuo 日高 和夫

Research Projects

Research Products

Co-Researchers

Maintenance of bone mineral density in Senescence Accelerated MiceP6 (SAMP6)

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effect of stress on methamphetamine intoxication- involvement of stress protein

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Changes in blood cytokine levels under stress conditions and their application to forensic diagnosis.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation of the mechanism of paraquat toxicity -Identification of the genes which are breakthrough for the toxicity-

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification and their function of paraquat-induced unknown genes in rat lungs.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A breakthrough in paraquat-induced pulmonary fibrosis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The contribution of nitric oxide to the paraquat-induced cell injury.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] DNA多型2009

Author(s)

Publisher

Data Source

[Journal Article] Water-restraint stress enhances methamphetamine-induced cardiotoxicity2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Water-restraint stress enhances methamphetamine-induced cardiotoxicity.2011

Author(s)

Journal Title

Data Source

[Journal Article] The effect of CAG repeat polymorphism in the glucocorticoid receptor on stress responses of mice exposed to waterimmersion restraint stress.2010

Author(s)

Journal Title

Data Source

[Journal Article] ELISA法による尿中8-OHdG測定-Ureaseおよびethanol沈殿処理の検討2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Methamphetamine protects against stress-induced gastric mucosal lesions in mice.2009

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Association between serotonin transporter gene polymorphisms and depressed mood caused by job stress in Japanese workers.2008

Author(s)

Journal Title

Data Source

[Journal Article] Gene expression in rat lungs during early response to paraquat-induced oxidative stress.2006

Author(s)

Journal Title

HIDAKA Kazuo 日高和夫