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SEKIGUCHI Takeshi  関口 武司

ORCIDConnect your ORCID iD *help
Researcher Number 00108193
Other IDs
Affiliation (based on the past Project Information) *help 2008 – 2010: いわき明星大学, 科学技術学部, 教授
2000 – 2003: いわき明星大学, 理工学部, 教授
Review Section/Research Field
Except Principal Investigator
Structural biochemistry / Structural biochemistry
Keywords
Except Principal Investigator
I-motif of G-quartets / DNA / base-intercalated duplex / Base-paired parallel duplex / Octa-stranded helix / X-Ray analysis / Damaged DNA / Functional nucleic acid / RNA world / RNA結合タンパク質 … More / ロイシルtRNA合成酵素 / ヘアピンDNA / リボザイム / RNA / マキシザイム / シュードウリジン / 5-ホルミルシトシン / 5-ホルミルウラシル / 平行二重らせん / 塩基積層型二重らせん構造 / 塩基対型平行二重らせん構造 / 八重らせん構造 / X線解析 / 損傷DNA / 機能性核酸 / RNAワールド / トレオニルtRNA合成酵素 / クレン古細菌 / X線結晶解析 / タンパク質合成系 / アミノアシルtRNA合成酵素 Less
  • Research Projects

    (2 results)
  • Research Products

    (37 results)
  • Co-Researchers

    (2 People)
  •  Structure and function of two different threonyl-tRNA synthetases of crenarchaea

    • Principal Investigator
      TAKENAKA Akio
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Structural biochemistry
    • Research Institution
      Iwaki Meisei University
  •  Structural basis for design of functional molecules in the DNA/RNA world

    • Principal Investigator
      TAKENAKA Akio
    • Project Period (FY)
      2000 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Structural biochemistry
    • Research Institution
      TOKYO INSTITUTE OF TECHNOLOGY

All 2010 2009 2008

All Journal Article Presentation Book

  • [Book] 耐熱酵素のさらなる安定性向上,酵素利用技術大系-基礎・解析から改変・高機能化・産業利用まで-(小宮山眞監修)2010

    • Author(s)
      竹中章郎・関口武司
    • Total Pages
      5
    • Publisher
      株式会社エヌ・ティー・エス(東京)
    • Data Source
      KAKENHI-PROJECT-20570104
  • [Book] 耐熱酵素のさらなる安定性向上ISBN978-4-86043-271-3, 518-522(酵素利用技術大系-基礎・解析から改変・高機能化・産業利用まで-)(小宮山眞監修)東京2010

    • Author(s)
      竹中章郎・関口武司著
    • Publisher
      株式会社エヌ・ティー・エス
    • Data Source
      KAKENHI-PROJECT-20570104
  • [Journal Article] Actinohivin: specific amino acid residues essential foranti-HIV activity2010

    • Author(s)
      Masaru Tsunoda, Kaoru Suzuki, Akio Takenaka, Takeshi Sekiguchi, Hideaki Umeyama, Jun Hirabayashi, Satoshi Omura, Haruo Tanaka
    • Journal Title

      J.Antibiot. 106

    • NAID

      10030710434

    • Data Source
      KAKENHI-PROJECT-20570104
  • [Journal Article] Crystallo-graphic study of wild type carbonic anhydrase αCA1 from Chlamydomonas reinhardtii2010

    • Author(s)
      Kaoru Suzuki, Satoru Shimizu, Ella Czarina Magat Juan, Takahiro Miyamoto, Fang Zhang, Md. Mominul Hoque, Yoshiteru Sato, Masaru Tsunoda, Takeshi Sekiguchi, Akio Takenaka
    • Journal Title

      Acta Crystallogr. F66

      Pages: 1082-1085

    • Data Source
      KAKENHI-PROJECT-20570104
  • [Journal Article] Crystallization and preliminary crystallographic studies of putative 3'-terminal phosphate cyclase from the crenarchaeon Sulfolobus tokodaii2009

    • Author(s)
      S.Shimuzu, T.Sekiguchi, A.Takenaka
    • Journal Title

      Acta Crystallogr. F65

      Pages: 565-570

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20570104
  • [Journal Article] Two complementary enzymes for threonylation of tRNA in crenarchaeota; crystal structure of Aeropyrum pernix threonyl-tRNA synthetase lacking a cis-editing domain2009

    • Author(s)
      Satoru Shimizu, Ella Czarina Magat Juan, Yu-ichiro Miyashita, Yoshiteru Sato, Md. Mominul Hoque, Kaoru Suzuki, Tsubasa Sagara, Masaru Tsunoda, Takeshi Sekiguchi, Anne-Catherine Dock-Bregeon, Dino Moras, Akio Takenaka
    • Journal Title

      J.Mol.Biol. 394

      Pages: 286-296

    • Data Source
      KAKENHI-PROJECT-20570104
  • [Journal Article] Mechanism by which the lectin actinohivin blocks HIV infection of target cells2009

    • Author(s)
      Haruo Tanaka, Harumi Chiba, Junji Inokoshi, Atsushi Kuno, Takahiro Sugai, Atsushi Takahashi, Yukishige Ito, Masaru Tsunoda, Kaoru Suzuki, Akio Takenaka, Takeshi Sekiguchi, Hideaki Umeyama, Jun Hirabayashi, Satoshi Omura
    • Journal Title

      Proc.Natl.Acad.Sci.USA 106

      Pages: 15633-15638

    • Data Source
      KAKENHI-PROJECT-20570104
  • [Journal Article] Crystal structure of D-3-hydroxybutyrate dehydrogenase, prepared in the presence of the substrate D-3-hydroxybutyrate NAD^+2009

    • Author(s)
      Md. Mominul Hoque, Satoru Shimizu, Ella Czarina Magat Juan, Yoshiteru Sato, Md. Tofazzal Hossain, Tamotsu Yamamoto, Shigeyuki Imamura, Kaoru Suzuki, Hitoshi Amano, Takeshi Sekiguchi, Masaru Tsunoda, Akio Takenaka
    • Journal Title

      Acta Crystallogr. F65

      Pages: 331-335

    • Data Source
      KAKENHI-PROJECT-20570104
  • [Journal Article] X-Ray Analyses of Two Evolutionary Different Threonyl-tRNA Synthetases Which Perform a Function by Supplementing Their Defects to Each Other in Crenarchaea2009

    • Author(s)
      S.Shimuzu, T.Sekiguchi, A.Takenaka
    • Journal Title

      Acta Crystallogr. A65

    • Data Source
      KAKENHI-PROJECT-20570104
  • [Journal Article] Crystallization preliminary crystallographic studies of putative RNA 3'-terminal phosphate cyclase from crenarchaeon Sulfolobus tokodaii2009

    • Author(s)
      Satoru Shimizu, Masanori Ohki, Nami Okubo, Kaoru Suzuki, Masaru Tsunoda, Takeshi Sekiguchi, Akio Takenaka
    • Journal Title

      Acta Crystallogr. F65

      Pages: 565-570

    • Data Source
      KAKENHI-PROJECT-20570104
  • [Journal Article] Two complementary enzymes for threonylation of tRN in crenarchaeota ; crystal structure of Aeropyrum pernix threonyl-tRNA synthetase lacking cis-eding domain2009

    • Author(s)
      Satoru Shimizu, Takeshi Sekiguchi, Akio Takenaka
    • Journal Title

      J.Mol.Biol., 394

      Pages: 286-296

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20570104
  • [Journal Article] Structures of Arthrobacter globiformis urate oxidase-lig complexes2008

    • Author(s)
      Ella Czarina Magat Juan, Md Mominul Hoque, Satoru Shimizu, Md Tofazzal Hossain, Tamotsu Yamamoto, Shigeyuki Imamura, Kaoru Suzuki, Masaru Tsunoda, Hitoshi Amano, Takeshi Sekiguchi, Akio Takenaka
    • Journal Title

      Acta Crystallogr. D64

      Pages: 815-822

    • Data Source
      KAKENHI-PROJECT-20570104
  • [Journal Article] Crystallographic study on two types of putative threonyl-tRNA synthetases from crenarchaea Aeropyrum pernix those from Sulfolobus tokodaii2008

    • Author(s)
      Satoru Shimizu, Ella Czarina Magat Juan, Yu-ichiro Miyashita, Yoshiteru Sato, Kaoru Suzuki, Masataka Yogiashi, Masaru Tsunoda, Anne-Catherine Dock-Bregeon, Dino Moras, Takeshi Sekiguchi, Akio Takenaka
    • Journal Title

      Acta Crystallogr. F64

      Pages: 903-910

    • Data Source
      KAKENHI-PROJECT-20570104
  • [Journal Article] Crystallization and preliminary crystallographic studies on putative threony1-tRNA synthetases from Aeropyrum pernix and Sulfolobus tokodai2008

    • Author(s)
      Satoru Shimizu, . . . . . . . . . . Takeshi Sekiguchi, Akio Takenaka
    • Journal Title

      Acta Crystallography F64

      Pages: 903-910

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20570104
  • [Journal Article] The structures of Alcaligenes faecalis D-3-hydroxybutyrate dehydrogenase before after NAD^+ acetate binding suggest a dynamical reaction mechanism as a member of the SDR family2008

    • Author(s)
      Md Mominul Hoque, Satoru Shimizu, Md Tofazzal Hossain, Tamotsu Yamamoto, Shigeyuki Imamura, Kaoru Suzuki, Masaru Tsunoda, Hitoshi Amano, Takeshi Sekiguchi, Akio Takenaka
    • Journal Title

      Acta Crystallogr. D64

      Pages: 496-505

    • Data Source
      KAKENHI-PROJECT-20570104
  • [Presentation] 古細菌Sulfolobus tokodaii由来トレオニルtRNA合成酵素の精製と結晶化構2010

    • Author(s)
      斉藤彰浩, 鈴木薫, 関口武司, 角田大, 竹中章郎
    • Organizer
      平成22年度化学系学協会東北大会 講演予稿集186
    • Place of Presentation
      盛岡
    • Year and Date
      2010-09-25
    • Data Source
      KAKENHI-PROJECT-20570104
  • [Presentation] Crystal structure of anti-HIV actinohivin in complexwith 1, 2-mannobiose2010

    • Author(s)
      M.M.Hoque, K.Suzuki, M.Tsunoda, A.Takahashi, T.Sekiguchi, H.Tanaka, A.Takenaka
    • Organizer
      日本結晶学会年会講演要旨集,126
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20570104
  • [Presentation] X-Ray analyses of two evolutionarily different threonyl-tRNA synthetases which perform a function by supplementing their defects to each other in crenarchaea2010

    • Author(s)
      A.Takenaka, S.Shimizu, Y.Sato, E.C.M.Juan, Y.Miyashita, T.Sagara, K.Suzuki, M.Tsunoda, T.Sekiguchi, A.C.D.Bregeon, D.Moras
    • Organizer
      Centre for Chemical Biologyセミナー
    • Place of Presentation
      Sheffield大学
    • Year and Date
      2010-10-18
    • Data Source
      KAKENHI-PROJECT-20570104
  • [Presentation] Two complementary enzymes for threonylation of tRNA in crenarchaeota ; crystal structure of Aeropyrum pernix threonyl-tRNA synthetase lacking a cis-editing domain2010

    • Author(s)
      A.Takenaka, S.Shimizu, Y.Sato, E.C.M.Juan, Y.Miyashita, T.Sagara, K.Suzuki, M.Tsunoda, T.Sekiguchi,, A.C.D.Bregeon, D.Moras
    • Organizer
      IGBMC(フランス国立遺伝学分子細胞生物学研究所)セミナー
    • Year and Date
      2010-10-23
    • Data Source
      KAKENHI-PROJECT-20570104
  • [Presentation] Two complementary enzymes for threonylation of tRNA in crenarchaeota ; crystal structure of Aeropyrum pernix threonyl-tRNA synthetase lacking a cis-editing domain2010

    • Author(s)
      Takenaka A., Miyashita Y., Sato Y., Dock-Bregeon A.C., Moras D., Sekiguchi T., Shimizu S.
    • Organizer
      IGBMCセミナー
    • Place of Presentation
      IGBMC(フランス国立遺伝学分子細胞生物学研究所)
    • Year and Date
      2010-10-23
    • Data Source
      KAKENHI-PROJECT-20570104
  • [Presentation] X-Ray analyses of two evolutionarily different threonyl-tRNA synthetases which perform a function by supplementing their defects to each other in crenarchaea2010

    • Author(s)
      Takenaka A., Miyashita Y., Sato Y., Dock-Bregeon A.C., Moras D., Sekiguchi T., Shimizu S.
    • Organizer
      化学生物学センターセミナー
    • Place of Presentation
      Sheffield大学, Centre for Chemical Biology
    • Year and Date
      2010-10-19
    • Data Source
      KAKENHI-PROJECT-20570104
  • [Presentation] 放線菌より単離した新規anti-HIV蛋白質アクチノヒビンならびにそのマンノビオースとの複合体のX線構造2009

    • Author(s)
      角田大, 鈴木薫, 相良翼, 高橋淳, 猪腰淳嗣, 大村智, 関口武司, 田中晴雄, 竹中章郎
    • Organizer
      第82回日本生化学会大会,要旨集4T9p-124P-629
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-20570104
  • [Presentation] Crystal Structures of Actinohivin, an Anti-HIV Protein from an Actinomycete, its Complex2009

    • Author(s)
      角田大, 鈴木薫, 相良翼, 高橋淳, 猪腰淳嗣, 大村智, 関口武司, 田中晴雄, 竹中章郎
    • Organizer
      25th European Crystallographic Meeting, ECM25 (Istanbul) Abstract
    • Data Source
      KAKENHI-PROJECT-20570104
  • [Presentation] Structure reaction mechanism of an enzyme RNA 3'-terminal phosphate cyclase in tRNA splicing2009

    • Author(s)
      竹中章郎, 大木正則, 大久保奈弥, 鈴木薫, 角田大, 関口武司, 清水了
    • Organizer
      tRNA Workshop, Aveiro, Portugal
    • Data Source
      KAKENHI-PROJECT-20570104
  • [Presentation] RNAプロセシングに関与するタンパク質,RNA3'-末端リン酸基環状化酵素の反応機構2009

    • Author(s)
      清水了, 大木正則, 大久保奈弥, 鈴木薫, 角田大, 関口武司, 竹中章郎
    • Organizer
      第11回RNA ミーティング,要旨集6
    • Place of Presentation
      新潟
    • Data Source
      KAKENHI-PROJECT-20570104
  • [Presentation] 新規抗HIVタンパク質アクチノヒビンのマンノビオースとの共結晶化2009

    • Author(s)
      相良翼, 斉藤彰浩, 高橋淳, 鈴木薫, 関口武司, 角田大, 田中晴雄, 竹中章郎
    • Organizer
      日本結晶学会2009年度年会,講演要旨集116
    • Data Source
      KAKENHI-PROJECT-20570104
  • [Presentation] X-Ray Analyses of Two Evolutionary Different Threonyl-tRNA Synthetases Which Perform a Function by Supplementing Their Defects to Each Other in Crenarchaea2009

    • Author(s)
      S.Shimizu, T.Sekiguchi, A.Takenaka
    • Organizer
      European Crystallographic Association
    • Place of Presentation
      ECM25, Istanbul,トルコ
    • Year and Date
      2009-08-19
    • Data Source
      KAKENHI-PROJECT-20570104
  • [Presentation] X-Ray Analyses of Two Evolutionary Different Threonyl-tRNA Synthetases Which Prefer a Functionby Supplementing Their Defects to Each Other in Crenarchaea2009

    • Author(s)
      S.Shimizu, Y.Sato, E.C.M.Juan, Y.Miyashita, T.Sagara, K.Suzuki, M.Tsunoda, T.Sekiguchi, A.C.D.Bregeon, D.Moras, A.Takenaka
    • Organizer
      25th European Crystallographic Meeting, ECM25 (Istanbul) Abstract
    • Data Source
      KAKENHI-PROJECT-20570104
  • [Presentation] X-Ray analyses of two evolutionarily different threonyl-tRNA synthetases which perform a function by supplementing their defects to each other in crenarchaea2009

    • Author(s)
      Satoru Shimizu, Yoshiteru Sato, Ella Czarina Magat Juan, Yu-ichiro Miyashita, Tsubasa Sagara, Kaoru Suzuki, Masaru Tsunoda, Takeshi Sekiguchi, Anne-Catherine Dock-Bregeon, Dino Moras, Akio Takenaka
    • Organizer
      Acta Crystallogr., A65, s17-s18
    • Data Source
      KAKENHI-PROJECT-20570104
  • [Presentation] Crystal structures of actinohivin, an anti-HIV proteinfrom an actinomycete, its complex with mannobiose2009

    • Author(s)
      角田大, 鈴木薫, 相良翼, 高橋淳, 猪腰淳嗣, 大村智, 関口武司, 田中晴雄, 竹中章郎
    • Organizer
      Acta Crystallogr., A65, s149-s150
    • Data Source
      KAKENHI-PROJECT-20570104
  • [Presentation] Two threonyl-tRNA synthetases with complementary functions ; Crystal structure of ThrRS-1 from Aeropyrum pernix2008

    • Author(s)
      Akio Takenaka, . . . . . . . . . Takeshi Sekiguchi
    • Organizer
      IUCr2008 Congress and General Assembly
    • Place of Presentation
      Osaka
    • Year and Date
      2008-08-25
    • Data Source
      KAKENHI-PROJECT-20570104
  • [Presentation] Crystal structure of α-carbonic anhydrase from Chlamydomonas reinhardtii2008

    • Author(s)
      Kaoru Suzuki, Satoru Shimizu, Risa Ohbayashi, Yoshiteru Sato, Akio Takenaka, Takeshi Sekiguchi, Shi-Yuan Yang
    • Organizer
      Acta Cryst., A64, C263
    • Data Source
      KAKENHI-PROJECT-20570104
  • [Presentation] Crystal structures of RNA 3'-terminal phosphate cyclase its complexes with Mg^<2+>+ATP, ATP or Mn^<2+>2008

    • Author(s)
      Satoru Shimizu, Masanori Ohki, Nami Ohkubo, Kaoru Suzuki, Masaru Tsunoda, Takeshi Sekiguchi, Akio Takenaka
    • Organizer
      Nucleic Acids Symp Ser.52, 221-222
    • Data Source
      KAKENHI-PROJECT-20570104
  • [Presentation] Two threonyl-tRNA synthetases with complementaryfunctions ; Crystal structure of ThrRS-1 fromAeropyrum pernix2008

    • Author(s)
      Akio Takenaka, Satoru Shimizu, Yu-ichiro Miyashita, Yoshiteru Sato, Ella Czarina Magat Juan, Kaoru Suzuki, Masaru Tsunoda, Anne-Catherine Dock-Bregeon, Dino Moras, Takeshi Sekiguchi
    • Organizer
      Acta Cryst., A64, C311
    • Data Source
      KAKENHI-PROJECT-20570104
  • [Presentation] Crystal structure of actinohivin ; A novel anti-humanimmunodeficiency virus protein2008

    • Author(s)
      角田大, 鈴木薫, 相良翼, 高橋淳, 猪腰淳嗣, 大村智, 関口武司, 竹中章郎, 田中晴雄
    • Organizer
      Acta Crystallogr., A64, C237
    • Data Source
      KAKENHI-PROJECT-20570104
  • [Presentation] The substrate recognition the catalytic reaction mechanisms of D-3hydroxybutyrate dehydrogenase2008

    • Author(s)
      Md Mominul Hoque, Satoru Shimizu, Md Tofazzal Hossain, Tamotsu Yamamoto, Shigeyuki Imamura, Kaoru Suzuki, Masaru Tsunoda, Hitoshi Amano, Takeshi Sekiguchi, Akio Takenaka
    • Organizer
      Acta Cryst., A64, C252
    • Data Source
      KAKENHI-PROJECT-20570104
  • [Presentation] RNA splicing related proteins; Crystal structure of RNA 3'-terminal phosphate cyclase2008

    • Author(s)
      Satoru Shimizu, Masanori Ohki, Nami Ohkubo, Kaoru Suzuki, Masaru Tsunoda, Takeshi Sekiguchi, Akio Takenaka
    • Organizer
      Acta Cryst., A64, C307
    • Data Source
      KAKENHI-PROJECT-20570104
  • 1.  TAKENAKA Akio (80016146)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 37 results
  • 2.  MORAS Dino
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 9 results

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