Hohdatsu Tsutomu 宝達勉

… Alternative Names

宝達努ホウダツツトム

HOHDATSU Tsutomu 宝達勉

HOHDASTU Stutomu 宝達勉

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Researcher Number	00129264
Other IDs
Affiliation (based on the past Project Information) *help	2013 – 2018: 北里大学, 獣医学部, 教授 2002: 北里大学, 獣医畜産学部, 助教授 1997 – 1998: 北里大学, 獣医畜産学部, 助教授 1991 – 1992: 北里大学, 獣医畜産学部, 講師
Review Section/Research Field	Principal Investigator Veterinary medical science / Basic veterinary science/Basic zootechnical science / 基礎獣医学 Except Principal Investigator 基礎獣医学 / Radiation science
Keywords	Principal Investigator 分子標的薬 / コロナウイルス / TNF-α / 抗ウイルス薬 / ワクチン / 猫伝染性腹膜炎 / ネコ伝染性腹膜炎ウイルス / ネコ / コレステロール / イトラコナゾール … More / 猫 / 治療 / FIP / CD8^+ T cell / feline infectious peritonitis virus / feline immunodeficiency virus / CD8^+T細胞 / CD8陽性Tリンパ球 / ネコ免疫不全ウイルス / 抗TNF製剤 / 抗サイトカイン療法 / 競合ELISA / マクロファ-ジ / Antibodyーdependent enhancement / モノクロ-ナル抗体 / ネココロナウイルス … More Except Principal Investigator BIV / PCR / Lentivirus / Bovine / レンチウイルス / レトロウイルス / ウシ / ウシ免疫不全ウイルス / 放射線治療 / FIV / エイズ治療 / HIV Less

Establishment of treatment and prevention methods for feline infectious peritonitis -from the basics to the practical use-Principal Investigator
- Principal Investigator
  
  Hohdatsu Tsutomu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Veterinary medical science
- Research Institution
  Kitasato University
Development of therapeutic agents and vaccines against feline infectious peritonitisPrincipal Investigator
- Principal Investigator
  
  Hohdatsu Tsutomu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Veterinary medical science
- Research Institution
  Kitasato University
放射線を用いたHIV失活によるエイズ治療の基礎的研究
- Principal Investigator
  
  伊藤伸彦
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Kitasato University
Roles of CD8^+ T cells in feline immunodeficiency virus and feline infectious peritonitis virus infections.Principal Investigator
- Principal Investigator
  
  HOHDATSU Tsutomu
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Basic veterinary science/Basic zootechnical science
- Research Institution
  KITASATO UNIVERSITY
ネココロナウイルス感染の識別とネコ伝染性腹膜炎ウイルスの感染増強作用に関する研究Principal Investigator
- Principal Investigator
  
  宝達勉
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  基礎獣医学
- Research Institution
  Kitasato University
Investigation of invasion by bovine immunodeficiency-like virus(BIV) in Japan and BIV isolation
- Principal Investigator
  
  KOYAMA Hiroyuki
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  基礎獣医学
- Research Institution
  Kitasato University

All 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation Book

[Book] Coronaviruses2015
- Author(s)
  Takano T, Hohdatsu T.
- Total Pages
  283
- Publisher
  Humana Press
- Data Source
  KAKENHI-PROJECT-25292183
[Journal Article] Antiviral activity of itraconazole against type I feline coronavirus infection2019
- Author(s)
  Takano T, Akiyama M, Doki T, Hohdatsu T
- Journal Title
  
  Veterinary Research
  
  Volume: 50(1) Issue: 1 Pages: 5-5
- DOI
  10.1186/s13567-019-0625-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05039
[Journal Article] Differential induction of type I interferon by type I and type II feline coronaviruses in vitro2018
- Author(s)
  Doki T, Yabe M, Takano T, Hohdatsu T
- Journal Title
  
  Research in Veterinary Science
  
  Volume: 120 Pages: 57-62
- DOI
  10.1016/j.rvsc.2018.09.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05039, KAKENHI-PROJECT-17K15372
[Journal Article] The cholesterol transport inhibitor U18666A inhibits type I feline coronavirus infection.2017
- Author(s)
  Takano T, Endoh M, Fukatsu H, Sakurada H, Doki T, Hohdatsu T.
- Journal Title
  
  Antiviral Research
  
  Volume: 145 Pages: 96-102
- DOI
  10.1016/j.antiviral.2017.07.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05039
[Journal Article] Antibody-dependent enhancement of serotype II feline enteric coronavirus infection in primary feline monocytes.2017
- Author(s)
  Takano T, Nakaguchi M, Doki T, Hohdatsu T.
- Journal Title
  
  Archives of Virology
  
  Volume: 162(11) Issue: 11 Pages: 3339-3345
- DOI
  10.1007/s00705-017-3489-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05039
[Journal Article] Differential effect of cholesterol on type I and II feline coronavirus infection2016
- Author(s)
  Takano T, Satomi Y, Oyama Y, Doki T, Hohdatsu T.
- Journal Title
  
  Arch Virol
  
  Volume: 161 Issue: 1 Pages: 125-133
- DOI
  10.1007/s00705-015-2655-0
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25292183
[Journal Article] Therapeutic effect of anti-feline TNF-alpha monoclonal antibody for feline infectious peritonitis.2016
- Author(s)
  Doki T, Takano T, Kawagoe K, Kito A, Hohdatsu T.
- Journal Title
  
  Res Vet Sci
  
  Volume: 104 Pages: 17-23
- DOI
  10.1016/j.rvsc.2015.11.005
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25292183
[Journal Article] Detection of canine astrovirus in dogs with diarrhea in Japan.2015
- Author(s)
  Takano T, Takashina M, Doki T, Hohdatsu T.
- Journal Title
  
  Archives of Virology
  
  Volume: in press Pages: 13-20
- DOI
  10.1016/j.virusres.2015.04.011
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26850185, KAKENHI-PROJECT-25292183
[Journal Article] Differential effects of viroporin inhibitors against feline infectious peritonitis virus serotypes I and II2015
- Author(s)
  Takano T, Nakano K, Doki T, Hohdatsu T.
- Journal Title
  
  Arch Virol.
  
  Volume: 160(5) Pages: 1163-1170
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25292183
[Journal Article] Screening and identification of T helper 1 and linear immunodominant antibody-binding epitopes in spike 1 domain and membrane protein of feline infectious peritonitis virus.2014
- Author(s)
  Takano T., Morioka, H., Gomi, K., Tomizawa, K., Doki, T. and Hohdatsu, T.
- Journal Title
  
  Vaccine
  
  Volume: 32 Issue: 16 Pages: 1834-1840
- DOI
  10.1016/j.vaccine.2014.01.074
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25292183
[Journal Article] Evaluation of protective efficacy of the synthetic peptide vaccine containing the T helper 1 epitope with CpG oligodeoxynucleotide against feline infectious peritonitis virus infection in cats.2014
- Author(s)
  Takano, T., Tomizawa, K., Morioka, H., Doki, T. and Hohdatsu, T.
- Journal Title
  
  Antivir Ther
  
  Volume: in press Issue: 7 Pages: 645-650
- DOI
  10.3851/imp2735
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25292183
[Journal Article] Use of recombinant nucleocapsid proteins for serological diagnosis of feline coronavirus infection by three immunochromatographic tests.2013
- Author(s)
  Takano, T., Ishihara, Y., Matsuoka, M., Yokota, S., Matsuoka-Kobayashi, Y., Doki, T. and Hohdatsu, T.
- Journal Title
  
  J Virol Methods
  
  Volume: 196 Pages: 1-6
- DOI
  10.1016/j.jviromet.2013.10.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25292183
[Journal Article] Generation, characterization and therapeutic potential of anti-feline TNF-alpha MAbs for feline infectious peritonitis.2013
- Author(s)
  Doki, T., Takano, T., Nishiyama, Y., Nakamura, M. and Hohdatsu, T.
- Journal Title
  
  Res Vet Sci
  
  Volume: 95 Issue: 3 Pages: 1248-1254
- DOI
  10.1016/j.rvsc.2013.09.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25292183
[Presentation] 猫伝染性腹膜炎ウイルスに対するイトラコナゾールの抗ウイルス作用2018
- Author(s)
  秋山美涼、高野友美、土岐朋義、宝達勉
- Organizer
  第161回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05039
[Presentation] 猫伝染性腹膜炎ウイルスに対するイトラコナゾールの抗ウイルス作用2018
- Author(s)
  秋山美涼、高野友美、土岐朋義、宝達勉
- Organizer
  第31回北里大学バイオサイエンスフォーラム
- Data Source
  KAKENHI-PROJECT-16H05039
[Presentation] 経口感染におけるI型猫伝染性腹膜炎ウイルスの抗体介在性感染増強作用2018
- Author(s)
  高野友美、山田慎二、土岐朋義、宝達勉
- Organizer
  第161回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05039
[Presentation] I型猫伝染性腹膜炎ウイルス温度感受性変異株の解析2018
- Author(s)
  土岐朋義、梅村悠香、伊藤瑞枝、小林晋、笹内綾乃、平野亨、渡部伸一、窪田庄太郎、高野友美、宝達勉
- Organizer
  第161回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05039
[Presentation] 新猫α1酸性糖タンパク質測定キットを用いたFIP診断への応用の可能性2017
- Author(s)
  工藤庄平、相馬武久、高野友美、小峯健一、照井潤、小峯優美子、土岐朋義、宝達勉
- Organizer
  第160回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05039
[Presentation] U18666AはI型猫伝染性腹膜炎ウイルスの増殖を抑制する2017
- Author(s)
  高野友美、櫻田晴子、遠藤美咲、深津寛昭、里見唯、土岐朋義、宝達勉
- Organizer
  第160回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05039
[Presentation] U18666AはI型猫伝染性腹膜炎ウイルスの増殖を抑制する2017
- Author(s)
  櫻田晴子、高野友美、遠藤美咲、深津寛昭、里見唯、土岐朋義、宝達勉
- Organizer
  第30回北里大学バイオサイエンスフォーラム
- Data Source
  KAKENHI-PROJECT-16H05039
[Presentation] ネココロナウイルス感染における株化細胞のIFN応答性の解析2017
- Author(s)
  土岐朋義、矢部翠、高野友美、宝達勉
- Organizer
  第160回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05039
[Presentation] ネココロナウイルスのコレステロール依存性細胞内侵入機構の解析2016
- Author(s)
  高野友美、遠藤美咲、深津寛昭、里見唯、小山優、土岐朋義、宝達勉
- Organizer
  第159回日本獣医学会学術集会
- Place of Presentation
  日本大学生物資源学部 (神奈川県藤沢市)
- Year and Date
  2016-09-06
- Data Source
  KAKENHI-PROJECT-16H05039
[Presentation] ネコ伝染性腹膜炎の治療薬への応用を目的としたIg定常領域付加型TNFレセプター製剤の作製2016
- Author(s)
  土岐朋義、高野友美、山口菜乃花、宝達勉
- Organizer
  第159回日本獣医学会学術集会
- Place of Presentation
  日本大学生物資源学部 (神奈川県藤沢市)
- Year and Date
  2016-09-06
- Data Source
  KAKENHI-PROJECT-16H05039
[Presentation] 猫伝染性腹膜炎ウイルスの構造蛋白質(MおよびS1 domain)におけるTh1 epitopeの検索とTh1活性誘導能について2013
- Author(s)
  高野友美、盛岡寛行、冨沢圭佑、五味宏二、土岐朋義、宝達勉
- Organizer
  日本獣医学会
- Place of Presentation
  岐阜大学(岐阜県岐阜市)
- Data Source
  KAKENHI-PROJECT-25292183
[Presentation] I型猫伝染性腹膜炎ウイルス(FIPV)KU-2株N蛋白質由来peptide(NP)のFIP発症予防効果の検討2013
- Author(s)
  土岐朋義、高野友美、冨沢圭佑、盛岡寛行、佐藤亮一、宝達勉
- Organizer
  日本獣医学会
- Place of Presentation
  岐阜大学(岐阜県岐阜市)
- Data Source
  KAKENHI-PROJECT-25292183
[Presentation] I型feline infectious peritonitis virus (FIPV) S蛋白質(S1ドメイン)由来peptideのcoronavirusに対する感染抑制効果
- Author(s)
  土岐朋義、高野友美、小山祐介、宝達勉
- Organizer
  第157回日本獣医学会学術集会
- Place of Presentation
  北海道大学（札幌）
- Year and Date
  2014-09-09 – 2014-09-12
- Data Source
  KAKENHI-PROJECT-25292183
[Presentation] ネコTNF-αを中和するマウスモノクローナル抗体のネコ伝染性腹膜炎(FIP)に対する治療効果とマウス・ネコキメラ化抗体の作製
- Author(s)
  土岐朋義、川越浩平、高野友美、宝達勉
- Organizer
  第11回日本獣医内科学アカデミー学術集会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2015-02-20 – 2015-02-22
- Data Source
  KAKENHI-PROJECT-25292183

1. KOYAMA Hiroyuki (00072372)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. Takano Tomomi (20525018)

# of Collaborated Projects: 2 results

# of Collaborated Products: 27 results
3. 伊藤伸彦 (00159899)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 打出毅 (20327456)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 夏堀雅宏 (50286366)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. DOKI TOMOYOSHI

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results

Hohdatsu Tsutomu 宝達 勉

宝達 努 ホウダツ ツトム

HOHDATSU Tsutomu 宝達 勉

HOHDASTU Stutomu 宝達 勉

Research Projects

Research Products

Co-Researchers

Establishment of treatment and prevention methods for feline infectious peritonitis -from the basics to the practical use-Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of therapeutic agents and vaccines against feline infectious peritonitisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

放射線を用いたHIV失活によるエイズ治療の基礎的研究

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Roles of CD8^+ T cells in feline immunodeficiency virus and feline infectious peritonitis virus infections.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ネココロナウイルス感染の識別とネコ伝染性腹膜炎ウイルスの感染増強作用に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation of invasion by bovine immunodeficiency-like virus(BIV) in Japan and BIV isolation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Coronaviruses2015

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Antiviral activity of itraconazole against type I feline coronavirus infection2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Differential induction of type I interferon by type I and type II feline coronaviruses in vitro2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The cholesterol transport inhibitor U18666A inhibits type I feline coronavirus infection.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Antibody-dependent enhancement of serotype II feline enteric coronavirus infection in primary feline monocytes.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Differential effect of cholesterol on type I and II feline coronavirus infection2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Therapeutic effect of anti-feline TNF-alpha monoclonal antibody for feline infectious peritonitis.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Detection of canine astrovirus in dogs with diarrhea in Japan.2015

Author(s)

Hohdatsu Tsutomu 宝達勉

宝達努ホウダツツトム

HOHDATSU Tsutomu 宝達勉

HOHDASTU Stutomu 宝達勉