IKEDA HIROSHI 池田洋

… Alternative Names

Researcher Number	00131219
Other IDs
Affiliation (based on the past Project Information) *help	2017: 愛知医科大学, 医学部, 教授 2014: 愛知医科大学, 医学部, 教授 2011: 愛知医科大学, 医学部, 教授 2007 – 2008: 愛知医科大学, 医学部, 教授 2003: Aichi Medical University, Faculty of Medicine, Professor, 医学部, 教授 1998 – 2003: 愛知医科大学, 医学部, 助教授
Review Section/Research Field	Except Principal Investigator Human pathology / Circulatory organs internal medicine / General surgery
Keywords	Except Principal Investigator 膵臓癌 / ヘッジホッグ / 分子病理 / SIL / ONO-4007 / シグナル伝達 / 浸潤 / 転移 / 病理学 / 癌 … More

Downstream of newly identified transcriptional repressor and its role in the progression of non-invasive breast cancer.
- Principal Investigator
  
  KASAI KENJI
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Aichi Medical University
Hedgehog signaling molecule SIL regulates the migration and progression of pancreatic ductal adenocarcinoma.
- Principal Investigator
  
  KASAI Kenji
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Aichi Medical University
Roles of SIX3 and SIL in the Hedgehog signaling during pancreatic carcinogenesis.
- Principal Investigator
  
  KASAI Kenji
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Aichi Medical University
Roles of the Hedgehog signaling in invasion and metastasis of pancreatic cancer
- Principal Investigator
  
  KASAI Kenji
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Aichi Medical University
Distribution of wall shear stress of vascular anastomosis and Irnmuno-hlstologicai study of anastomotic Intimal hyperplasia
- Principal Investigator
  
  ISHIBASHI Hiroyuki
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Aichi Medical University
Local Drug Delivery of ONO-4007 Inhibits Neointimal Hyperplasia in Dogs.
- Principal Investigator
  
  WAKIDA Yasushi
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  AICHI MEDICAL UNIVERSITY

All 2015 2014 2013 2012 2011 2010 2009 2008 Other

All Journal Article Presentation

[Journal Article] GLI1 orchestrates CXCR4/CXCR7 signaling to enhance migration and metastasis of breast cancer cells2015
- Author(s)
  Shingo Inaguma, Miho Riku, Hideaki Ito, Takumi Tsunoda, Hiroshi Ikeda, Kenji Kasai
- Journal Title
  
  Oncotarget
  
  Volume: Vol6, No32 Pages: 33648-33657
- DOI
  10.18632/oncotarget.5203
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K08358
[Journal Article] Down-regulation of the zinc-finger homeobox protein TSHZ2 releases GLI1 from the nuclear repressor complex to restore its transcriptional activity during mammary tumorigenesis2015
- Author(s)
  Miho Riku, Shingo Inaguma, Hideaki Ito, Takumi Tsunoda, Hiroshi Ikeda, Kenji Kasai
- Journal Title
  
  Oncotarget
  
  Volume: vol7, No5 Pages: 5690-5701
- DOI
  10.18632/oncotarget.6788
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K08358
[Journal Article] GLI1 interferes with the DNA mismatch repair system in pancreatic cancer through BHLHE41-mediated suppression of MLH1.2013
- Author(s)
  Shingo Inaguma, Miho Riku, Mitsuyoshi Hashimoto, Hideki Murakami, Shinsuke Saga, Hiroshi Ikeda and Kenji Kasai.
- Journal Title
  
  Cancer Research
  
  Volume: 73 Pages: 7313-7323
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590456
[Journal Article] GLI1 modulates EMT in pancreatic cancer--letter.2012
- Author(s)
  Shingo Inaguma, Kenji Kasai, Mitsuyoshi Hashimoto, Hiroshi Ikeda
- Journal Title
  
  Cancer Res.
  
  Volume: (in press) Pages: 3702-3
- DOI
  10.1158/0008-5472.can-12-0379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590408, KAKENHI-PROJECT-23790424, KAKENHI-PROJECT-24590456
[Journal Article] GLI1 facilitates the migration and invasion of pancreatic cancer cells through MUC5AC-mediated attenuation of E-cadherin2011
- Author(s)
  Shingo Inaguma, Kenji Kasai, Hiroshi Ikeda
- Journal Title
  
  Oncogene
  
  Volume: 30 Pages: 714-723
- DOI
  10.1038/onc.2010.459
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590408
[Journal Article] GLI1 facilitates the migarion and invasion of pancreatic cancer cellls through MUC5AC-mediated attenuation of E-cadherin.2011
- Author(s)
  S Inaguma, K Kasai, H Ikeda.
- Journal Title
  
  Oncogene
  
  Volume: 30巻 Pages: 714-723
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590408
[Journal Article] SCL/TAL1 Interrupting Locus derepresses GLI1 from the negative control of Suppressor-of-Fused in pancreatic cancer cell2008
- Author(s)
  Kenji Kasai, Shingo Inaguma, Akiko Yoneyama, Kazuhiro Yoshikawa, Hiroshi Ikeda
- Journal Title
  
  Cancer Research 66
  
  Pages: 7723-7729
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590371
[Presentation] ヘッジホッグ系転写因子GLI1はCXCL12/CXCR4経路の活性化により乳癌細胞の遊走能を亢進させる2015
- Author(s)
  稲熊真悟、笠井謙次、伊藤秀明、陸美穂、池田洋
- Organizer
  第104回日本病理学会総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-04-30
- Data Source
  KAKENHI-PROJECT-15K08358
[Presentation] 新規転写抑制因子TSHZ2からみた乳癌進展機構2015
- Author(s)
  陸美穂、笠井謙次、稲熊真悟、伊藤秀明、池田洋
- Organizer
  第104回日本病理学会総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-04-30
- Data Source
  KAKENHI-PROJECT-15K08358
[Presentation] ヘッジホッグシグナル系転写因子ZIC2はFGFR3、ANXA8L2発現誘導を介して膵発がんを促進する2014
- Author(s)
  稲熊真悟、笠井謙次、橋本光義、陸美穂、池田洋
- Organizer
  第103回日本病理学会総会
- Place of Presentation
  広島国際会議場
- Data Source
  KAKENHI-PROJECT-24590456
[Presentation] ZIC2 is an indispensable transcriptional factor for the cell gwoth of pancreatic duct adenocarcinoma.2014
- Author(s)
  S Inaguma, K Kasai, M Hashimoto, M Riku, H Ikeda
- Organizer
  103rd Annuak Meeting of USCAP
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-24590456
[Presentation] Hedgehogシグナル系転写活性化因子GLI1から見た膵臓前がん病変の細胞生物学的特性2013
- Author(s)
  稲熊真悟、笠井謙次。橋本光義、陸美穂、池田洋
- Organizer
  第102回日本病理学会総会
- Place of Presentation
  ロイトン札幌
- Data Source
  KAKENHI-PROJECT-24590456
[Presentation] 膵臓癌細胞において転写因子GLI1はBHLHE41依存性にMLH1発現を抑制し、ミスマッチ修復機構の機能不全を惹起する2013
- Author(s)
  稲熊真悟、笠井謙次、橋本光義、陸美穂、池田洋
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24590456
[Presentation] 胃小細胞癌の一例:遺伝子変異LOH解析を含めた検討2011
- Author(s)
  稲熊真悟、笠井謙次、池田洋
- Organizer
  第100回日本病理学会総会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2011-04-29
- Data Source
  KAKENHI-PROJECT-21590408
[Presentation] 胃小細胞癌の一例遺伝子変異・LOH解析を含めた検討2011
- Author(s)
  稲熊真悟、笠井謙次、池田洋
- Organizer
  第100回日本病理学会総会
- Place of Presentation
  パシフィコ横浜(横浜市)(一般示説)
- Year and Date
  2011-04-29
- Data Source
  KAKENHI-PROJECT-21590408
[Presentation] GLI1はMUC5ACの発現誘導によってE-cadherinによる細胞間接着を阻害し膵癌細胞の遊走・浸潤を促進する2010
- Author(s)
  稲熊真悟、笠井謙次、米山亜紀子、池田洋
- Organizer
  第99回日本病理学会総会
- Place of Presentation
  京王プラザホテル(東京都)
- Year and Date
  2010-04-29
- Data Source
  KAKENHI-PROJECT-21590408
[Presentation] 膵臓癌においてGLI1はbHLH型転写抑制因子DEC2の発現を直接誘導しMLH1を介した遺伝子不安定性に寄与する2009
- Author(s)
  稲熊真悟、笠井謙次、米山亜紀子、池田洋
- Organizer
  第98回日本病理学会総会
- Place of Presentation
  国立京都国際会館(京都市)
- Year and Date
  2009-05-03
- Data Source
  KAKENHI-PROJECT-21590408
[Presentation] 膵臓癌およびPancreatic Intraepithelial Neoplasia(PanIN)におけるSIL発現状況の免疫組織学的解析2009
- Author(s)
  米山亜紀子、稲熊真悟、笠井謙次、池田洋
- Organizer
  第98回日本病理学会総会
- Place of Presentation
  国立京都国際会館(京都市)
- Year and Date
  2009-05-03
- Data Source
  KAKENHI-PROJECT-21590408
[Presentation] がん細胞において転写因子GLI1はbHLH型転写抑制因子DEC2、HES1の発現を直接誘導する2008
- Author(s)
  稲熊真悟、笠井謙次、池田洋
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋市
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-19590371
[Presentation] 膵臓癌におけるHedgehogシグナル系転写因子GLI1のSUFU依存性制御からの離脱機構2008
- Author(s)
  笠井謙次、稲熊真悟、米山亜紀子、池田洋
- Organizer
  第97回日本病理学会総会
- Place of Presentation
  金沢市
- Year and Date
  2008-05-17
- Data Source
  KAKENHI-PROJECT-19590371
[Presentation] SILによるGLI1のSUFU依存性制御からの離脱機構2008
- Author(s)
  笠井謙次、稲熊真悟、池田洋
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋市
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-19590371
[Presentation] 膵前癌病変におけるShh-GLI1標的遺伝子MUC5ACの発現解析2008
- Author(s)
  稲熊真悟、笠井謙次、米山亜紀子、池田洋
- Organizer
  第97回日本病理学会総会
- Place of Presentation
  金沢市
- Year and Date
  2008-05-17
- Data Source
  KAKENHI-PROJECT-19590371
[Presentation] ヘッジホッグ系転写因子GLI1はCXCL12/CXCR4経路の活性化により乳癌細胞の遊走能を亢進させる
- Author(s)
  稲熊真悟、笠井謙次、伊藤秀明、陸美穂、池田洋
- Organizer
  第104回日本病理学会総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-04-30 – 2015-05-02
- Data Source
  KAKENHI-PROJECT-24590456

1. INAGUMA Shingo (80410786)

# of Collaborated Projects: 5 results

# of Collaborated Products: 23 results
2. KASAI Kenji (70242857)

# of Collaborated Projects: 4 results

# of Collaborated Products: 23 results
3. ITO Hideaki (90711276)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
4. WAKIDA Yasushi (90201152)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KAKIHANA Masashi (20298582)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. OZAKI Yukio (50298569)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. FUKUTA Motoyuki (50247722)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. ISHIBASHI Hiroyuki (10257660)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. KIYOTA Yoshiharu (30298591)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

IKEDA HIROSHI 池田 洋

IKEDA Hiroshi 池田 洋

Research Projects

Research Products

Co-Researchers

Downstream of newly identified transcriptional repressor and its role in the progression of non-invasive breast cancer.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Hedgehog signaling molecule SIL regulates the migration and progression of pancreatic ductal adenocarcinoma.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Roles of SIX3 and SIL in the Hedgehog signaling during pancreatic carcinogenesis.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Roles of the Hedgehog signaling in invasion and metastasis of pancreatic cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Distribution of wall shear stress of vascular anastomosis and Irnmuno-hlstologicai study of anastomotic Intimal hyperplasia

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Local Drug Delivery of ONO-4007 Inhibits Neointimal Hyperplasia in Dogs.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] GLI1 orchestrates CXCR4/CXCR7 signaling to enhance migration and metastasis of breast cancer cells2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Down-regulation of the zinc-finger homeobox protein TSHZ2 releases GLI1 from the nuclear repressor complex to restore its transcriptional activity during mammary tumorigenesis2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] GLI1 interferes with the DNA mismatch repair system in pancreatic cancer through BHLHE41-mediated suppression of MLH1.2013

Author(s)

Journal Title

Data Source

[Journal Article] GLI1 modulates EMT in pancreatic cancer--letter.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] GLI1 facilitates the migration and invasion of pancreatic cancer cells through MUC5AC-mediated attenuation of E-cadherin2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] GLI1 facilitates the migarion and invasion of pancreatic cancer cellls through MUC5AC-mediated attenuation of E-cadherin.2011

Author(s)

Journal Title

Data Source

[Journal Article] SCL/TAL1 Interrupting Locus derepresses GLI1 from the negative control of Suppressor-of-Fused in pancreatic cancer cell2008

Author(s)

Journal Title

Data Source

[Presentation] ヘッジホッグ系転写因子GLI1はCXCL12/CXCR4経路の活性化により乳癌細胞の遊走能を亢進させる2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 新規転写抑制因子TSHZ2からみた乳癌進展機構2015

IKEDA HIROSHI 池田洋

IKEDA Hiroshi 池田洋