MIYAKE Yasuko 三宅康子

… Alternative Names

MIYAKE Yasuo 三宅康子

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Researcher Number	00132936
Affiliation (based on the past Project Information) *help	2002 – 2004: 国立循環器病センター研究所, 病因部, 室長 1997: National Cardiovascular Center Research Institute, Department of Etiology and Pa, 病因部, 室長 1989 – 1995: NCVC, Dept. Etiology/Pathogenesis, Chief, 病因部, 室長 1986 – 1988: 国立循環器病センター, 研究所・病因部, 室長 1987: 国立循環器病センター研究所, 病因部, 室長 1986: 循病セ, その他, 研究員
Review Section/Research Field	Principal Investigator Human genetics / Laboratory medicine Except Principal Investigator 内分泌・代謝学
Keywords	Principal Investigator 家族性高コレステロール血症 / 遺伝子変異 / common mutation / LDLレセプター / LDLレセプター遺伝子 / レセプターの生合成 / 細胞膜蛋白質 / スプライシング異常 / genetic basis of hypercholesterolemia / gene diagnosis … More / variety of mutations / familial hypercholesterolemia / LDL receptor / mild type変異 / 表現形 / 高頻度変異 / 高脂血症の遺伝素因 / 遺伝子診断 / 変異の多様性 / ヒト遺伝病 / LDLセプター / 線維芽細胞 / 細胞内プロセシング / EGF前駆体相同ドメイン / アミノ酸置換 / 点変異 / 低比重リポ蛋白質 … More Except Principal Investigator Atherosclerosis / Cholesterol / アポリポ蛋白 / LDL receptor / マクロファージ / 動脈硬化 / Lipoprotein lipase / リポ蛋白リパーゼ / コレステロール / 粥状動脈硬化 / Hyperlipoproteinemia / Apolipoprotein / 高脂血症 / Lipoprotein / Apolipoprotein E / LDL受容体 / リポ蛋白 / 動脈硬化症 / Familial hypercholesterolemia / Hyperlipidemia / Plasma lipoprotein / 虚血性心疾患 / 家族性高コレステロール血症 / アポリポ蛋白E5とE7 / 低密度リポ蛋白レセプター(LDLレセプター) / 家族性高コンステロール血症 / 血漿リポ蛋白 / リポタンパク質リパ-ゼ / 〓状動脈硬化 / コレステロ-ル / 家族性高コレステロ-ル血症 / リポタンパク質リバ-ゼ / アポリポタンパク質E / LDLレセプタ- / 血漿リポタンパク質 / Transforming growth factor-beta1 / Scavenger receptor / Macrophage / Low-density lipoprotein / 泡沫化 / THP-1細胞 / PAI-1 / TGF-β1 / サイトカイン / TGF-β / スカベンジャー受容体 / LDL / Apolipoproteins / Hepatic lipase / LDL-receptor / Triglyceride / 肝トリグリセライドリパーゼ / LDL-レセプター / トリグリセライド / 血漿リポ蛋白代謝 / Mutant / 変異種 / アポリポ蛋白E Less

Molecular basis of genetic hypercholesterolemiaPrincipal Investigator
- Principal Investigator
  
  MIYAKE Yasuko
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  National Cardiovascular Center Research Institute
日本人に比較的高頻度に認められるLDLレセプター遺伝子変異の特徴についてPrincipal Investigator
- Principal Investigator
  
  三宅康子
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Human genetics
- Research Institution
  National Cardiovascular Center Research Institute
Studies on the regulation of cholesteryl ester synthesis and mechanism of lipid accumulation in macrophage cells
- Principal Investigator
  
  YAMAMURA Taku, 斯波真理子
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  内分泌・代謝学
- Research Institution
  National Cardiovascular Center Research Institute
ヒトLDL(低比重リポ蛋白質)レセプターの突然変異における遺伝子解析Principal Investigator
- Principal Investigator
  
  三宅康子
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Human genetics
- Research Institution
  National Cardiovascular Center Research Institute
Studies on Hyperlipoproteinemic Trait, Especially Plasma Apolipoprotein Mutants, as a Risk Factor for Atherosclerosis
- Principal Investigator
  
  YAMAMURA Taku
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  内分泌・代謝学
- Research Institution
  National Cardiovascular Center Research Institute
MOLECULAR-GENETIC STUDY OF FAMILIAR HYPERLIPOPROTEINEMIA RELATED TO ATHEROSCLEROSIS
- Principal Investigator
  
  YAMAMOTO Akira
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  内分泌・代謝学
- Research Institution
  NATIONAL CARDIOVASCULAR CENTER RESEARCH INSTITUTE
家族性高コレステロール血症の原因遺伝子に解析Principal Investigator
- Principal Investigator
  
  三宅康子
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  National Cardiovascular Center Research Institute
家族性高コレステロール血症の原因遺伝子の解析Principal Investigator
- Principal Investigator
  
  三宅康子
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  National Cardiovascular Center Research Institute
Plasma Apolipoprotein Mutants and their Implication on Lipoprotein Metabolism
- Principal Investigator
  
  YAMAMURA Taku
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内分泌・代謝学
- Research Institution
  National Cardiovascular Center Research Institute
ヒトLDL(低比重リポ蛋白)レセプターの突然変異における遺伝子解析Principal Investigator
- Principal Investigator
  
  三宅康子
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Human genetics
- Research Institution
  National Cardiovascular Center Research Institute
ヒトLDL(低比重リポ蛋白)受容体の突然変異に関する研究Principal Investigator
- Principal Investigator
  
  三宅康子
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Human genetics
- Research Institution
  National Cardiovascular Center Research Institute
Molecular Basis of the Etiology and Pathogenesis of Hyperlipoproteinemia
- Principal Investigator
  
  YAMAMOTO Akira
- Project Period (FY)
  1986 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  内分泌・代謝学
- Research Institution
  National Cardiovascular Center Research Institute (NCVC)

All 2003 2002

All Journal Article

[Journal Article] The molecular basis of familial hypercholesterolemia in Japanese population2003
- Author(s)
  Miyake, Y., Yamamura, T., Yamamoto, A.
- Journal Title
  
  Atherosclerosis Suppl. 3
  
  Pages: 224-224
- Data Source
  KAKENHI-PROJECT-14572198
[Journal Article] The molecular basis of familial hypercholesterolemia in Japanese population.2003
- Author(s)
  Miyake, Y., Yamamura, T., Yamamoto, A.
- Journal Title
  
  Atherosclerosis Suppl.3
  
  Pages: 224-224
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14572198
[Journal Article] The molecular basis of familial hypercholesterolemia in Japanese Population.2003
- Author(s)
  Miyake, Y., Yamamura, T., Yamamoto, A.
- Journal Title
  
  Atherosclerosis Suppl.3
  
  Pages: 224-224
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14572198
[Journal Article] mild type FH L547V変異ホモ接合体における臨床症状2002
- Author(s)
  三宅康子, 山村卓, 丸山貴生, 酒井尚彦, 松澤佑次
- Journal Title
  
  日本分子医学会記録 38
  
  Pages: 48-48
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14572198

1. YAMAMURA Taku (20132938)

# of Collaborated Projects: 11 results

# of Collaborated Products: 4 results
2. YAMAMOTO Akira (00028408)

# of Collaborated Projects: 8 results

# of Collaborated Products: 0 results
3. IKEDA Yasuyuki (90176107)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. TAKAICHI Shigeko (00093930)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. TAJIMA Shoji (50132931)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. TAKAGI Atsuko (90179416)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. KAWAGUCHI Akito (70214608)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. YAKOYAMA Shinji (10142192)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 斯波真理子 (70271575)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. MARUYAMA Takao

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. SIGANO Ryo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 豊田康嗣

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

MIYAKE Yasuko 三宅 康子

MIYAKE Yasuo 三宅 康子

Research Projects

Research Products

Co-Researchers

Molecular basis of genetic hypercholesterolemiaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

日本人に比較的高頻度に認められるLDLレセプター遺伝子変異の特徴についてPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on the regulation of cholesteryl ester synthesis and mechanism of lipid accumulation in macrophage cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ヒトLDL(低比重リポ蛋白質)レセプターの突然変異における遺伝子解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on Hyperlipoproteinemic Trait, Especially Plasma Apolipoprotein Mutants, as a Risk Factor for Atherosclerosis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

MOLECULAR-GENETIC STUDY OF FAMILIAR HYPERLIPOPROTEINEMIA RELATED TO ATHEROSCLEROSIS

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

家族性高コレステロール血症の原因遺伝子に解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

家族性高コレステロール血症の原因遺伝子の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Plasma Apolipoprotein Mutants and their Implication on Lipoprotein Metabolism

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ヒトLDL(低比重リポ蛋白)レセプターの突然変異における遺伝子解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ヒトLDL(低比重リポ蛋白)受容体の突然変異に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular Basis of the Etiology and Pathogenesis of Hyperlipoproteinemia

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] The molecular basis of familial hypercholesterolemia in Japanese population2003

Author(s)

Journal Title

Data Source

[Journal Article] The molecular basis of familial hypercholesterolemia in Japanese population.2003

MIYAKE Yasuko 三宅康子

MIYAKE Yasuo 三宅康子