NAGATA Hiroshi 永田博司

Researcher Number	00146599
Other IDs
Affiliation (based on the past Project Information) *help	2007: 慶應大, 医学部, 助教授 2001 – 2006: KEIO UNIVERSITY, MEDICINE, ASSOCATE PROFESSOR, 医学部, 助教授 2000: 慶應義塾大学, 医学部, 講師 1999 – 2000: 慶應義塾大学, 医学部, 専任講師
Review Section/Research Field	Principal Investigator Gastroenterology / Gastroenterology Except Principal Investigator Gastroenterology / Digestive surgery / Parasitology (including Sanitary zoology) / Biomedical engineering/Biological material science / Gastroenterology
Keywords	Principal Investigator マクロファージ / dendritic cell / macrophage / 樹状細胞 / リンパ球ホーミング / chemokine / mesenteric lymph node / lymphatic vessel in mesentery / colitis / ケモカイン … More / 腸間膜リンパ節 / 腸間膜リンパ管 / 腸炎 / cell-to-cell interaction / cancer metastasis / lymhphocyte hhoming / marginal sinus / lymph node / 辺緑洞 / 細胞間相互反応 / 癌転移 / 辺縁洞 / リンパ節 / 光線力学的治療 / レーザー照射 / 酸素分圧 / リンパ管新生 / リンパ洞 … More Except Principal Investigator AH130 / MPC polymer / Micrometastasis / Sentinel node / Signal transduction / SWAP antigen / TLR ligands / Schistosoma mansoni / sodium bicarbonate cotransporter / ion transport / CFTR chloride channel / 活性酸素 / アポトーシス / H.pylori / Sentinel Node / リンパ系 / 抗腫瘍化学療法 / リンパ節転移 / Drug delivery system / 微小転移 / MPC Polymer / AHI30 / Convulsion-inducing lipoprotein(CILIP) / FX-activatina procoagulant / Egg granulomas / リンパ球 / マクロファージ / モノクロナル抗体 / 凝固活性化因子(CILIP) / 中卵性肉芽腫 / 凝固第X因子 / 組織因子 / 虫卵性肉芽腫 / シグナル伝達機構 / 誘導機構 / 凝固活性化リポ蛋白 / マンソン住血吸虫 / Convulsion-inducing lipoprotein (CILIP) / FX-activating procoagulant / Egg granuloma / Confocal laser microscopy / Porphyrin / Cancer cell / Endothelial cell / Platelet thrombosis / Apoptosis / Active oxygen / Photodynamic therapy / 共焦点レーザー顕微鏡 / ポルフィリン / 癌細胞 / 内皮細胞 / 血小板血栓 / 光線力学的治療 / intravital microscopy / luminal pH / capsaicin-sensitive afferent nerves / acid-sensing pathway / murosal defense / sodium bicarbonate cotransport / 生体顕微鏡 / 管腔内pH / capsaicin感受性知覚神経 / 酸感知機構 / transport / 粘膜防御 / leukocyte adhesion / leukocyte rolling / apoptosis / metal ion / monochloramine / oxidative stress / microcirculation / 鉄 / 白血球接着 / 白血球転回 / 微量金属 / スナネズミ / 白血球活性化 / 亜鉛 / モノクロラミン / 酸化ストレス / 微小循環障害 / 胃粘膜修復 / 胃粘膜傷害 / 胃腺 / Musashi-1 / 幹細胞 Less

癌転移を制御する所属リンパ節特異的微小環境の解明Principal Investigator
- Principal Investigator
  
  永田博司
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
Musashi-1をマーカーとした胃粘膜多能性幹細胞の同定と分離Principal Investigator
- Principal Investigator
  
  永田博司, 木村裕之
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
Development of novel trans-lymphatic chemotherapy targeted to micrometastasis in sentinel lymph nodes using a phospholipids polymer-paclitaxel conjugate
- Principal Investigator
  
  KITAGAWA Yuko
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Keio University
Identification of FX-activating molecules of convulsion-inducing lipoprotein purified from egg granulomas in Schistosoma mansoni-infected mice and of its inducing mechanism
- Principal Investigator
  
  TANABE Masanobu
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Parasitology (including Sanitary zoology)
- Research Institution
  Keio University
Study on vascular shutdown effects of carcinoma blood vessels and cytotoxic effects of carcinoma cells induced by photochemical reaction.
- Principal Investigator
  
  MINAMITANI Haruyuki
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Keio University
MECHANISM OF REGULATING MOBILIZATION AND MIGRATION OF ANTIGEN PRESENTING CELLS DURING INFLAMMATIONPrincipal Investigator
- Principal Investigator
  
  NAGATA Hiroshi
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
Roles of ion transports in gastrointestinal mucosal defense, and their clinical application
- Principal Investigator
  
  AKIBA Yasutada
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
CELL-TO-CELL INTERACTION IN THE MARGINALSINUS OF MESENTERIC LYMPH NODEPrincipal Investigator
- Principal Investigator
  
  NAGATA Hiroshi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
The mechanism of Helicobacter pylori-induced gastric mucosal injury, involvement of heme iron and oxidative stress.
- Principal Investigator
  
  SUZUKI Hidekazu
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  KEIO UNIVERSITY

All 2006 2005 2004 2003

All Journal Article Book

[Book] 分化阻止転写因子HESの発現をマーカーとした胃粘膜修復機構の検討。消化器病学の進歩2005モノグラフ、消化器病学のニューフロンテイア編2005
- Author(s)
  永田博司
- Total Pages
  4
- Publisher
  メデイカルレビュー社
- Data Source
  KAKENHI-PROJECT-16659188
[Journal Article] Expression of Musashi-1 the rat stomach and changes during mucosal injury and restitution.2006
- Author(s)
  Nagata H
- Journal Title
  
  FEBS Lett 580・1
  
  Pages: 27-33
- Data Source
  KAKENHI-PROJECT-16659188
[Journal Article] 胃癌は骨髄由来細胞から発生する(海外論文紹介)2006
- Author(s)
  永田博司
- Journal Title
  
  GI.Research 14・1
  
  Pages: 98-100
- Data Source
  KAKENHI-PROJECT-16659188
[Journal Article] Chronic allergy to dietary ovalbumin induces lymphocyte migration to rat small intestinal mucosa that is inhibited by MAdCAM-1.2004
- Author(s)
  Ogawa T, Miura S, Tsuzuki Y, Ogino T, Teramoto K, Inamura T, Watanabe C, Hokari R, Nagata H, Ishii H.
- Journal Title
  
  Am J Physiol (Gastrointest Liver Physiol 286)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570507
[Journal Article] Limited capability of regional lymph nodes to eradicate metastatic cancer cells.2004
- Author(s)
  Nagata H, Arai T, Soejima Y, Suzuki H, Ishii H, Hibi T.
- Journal Title
  
  Cancer Res 64・22
  
  Pages: 8239-8248
- Data Source
  KAKENHI-PROJECT-14570507
[Journal Article] Limited capability of regional lymph nodes to eradicate metastatic cancer cells.2004
- Author(s)
  Nagata H, Arai T, Soejima Y, Suzuki H, Ishii H, Hibi T.
- Journal Title
  
  Cancer Res 64
  
  Pages: 8239-8248
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570507
[Journal Article] Demonstration of functional role of TECK/CCL25 in T lymphocyte-endothelium interaction in inflamed and uninflamed intestinal mucosa.2004
- Author(s)
  Hosoe N, Miura 5, Watanabe C, Tsuzuki Y, Hokari R, Oyama T, Fujiyama Y, Nagata H, Isahii H.
- Journal Title
  
  Am J Physiol(Gastrointest Liver Physiol 286)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570507
[Journal Article] 腸リンパ装置における免疫担当細胞の遊走2004
- Author(s)
  永田博司, 小林央, 穂苅量太, 三浦総一郎, 日比紀文
- Journal Title
  
  リンパ学 27・2
  
  Pages: 74-78
- Data Source
  KAKENHI-PROJECT-14570507
[Journal Article] Chronic allergy to dietary ovalbumin induces lymphocyte migiration to rat small intestinal mucosa that is inhibited by MAdCAM-1.2004
- Author(s)
  Ogawa T, Miura S, Tsuzuki Y, Nagata H, et al.
- Journal Title
  
  Am J Physiol (Gastrointest Liver Physiol) 286
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570507
[Journal Article] In situ demonstration of dendritic cell migration from rat intestine to mesenteric lymph nodes : relationships to maturation and role of chemokines.2004
- Author(s)
  Kobayashi H, Miura S, Nagata H, Tsuzuki Y et al.
- Journal Title
  
  J Leukoc Biol 75・3
  
  Pages: 434-442
- Data Source
  KAKENHI-PROJECT-14570507
[Journal Article] Demonstration of functional role of TECK/CCL25 in Tlymphocyte-endothelium interaction in inflamed and uninflamed intestinal mucosa.2004
- Author(s)
  Hosoe N, Miura S, Watanabe C, Nagata H, et al.
- Journal Title
  
  Am J Physiol (Gastrointest Liver Physio) 286
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570507
[Journal Article] Chronic allergy to dietary ovalbumin induces lymphocyte migration to rat small intestinal mucosa that is inhibited by MAdCAM-1.2004
- Author(s)
  Ogawa T, Miura S, Tsuzuki Y, Nagata H et al.
- Journal Title
  
  Am J Physiol (Gastrointest Liver Physiol) 286
- Data Source
  KAKENHI-PROJECT-14570507
[Journal Article] In situ demonstration of dendritic cell migration from rat intestine to mesenteric lymph nodes : relationships to maturation and role of chemokines.2004
- Author(s)
  Kobayashi H, Miura S, Nagata H, Tsuzuki Y, Hokari R, Ogino T, Watanabe C, Azuma T, Ishii H.
- Journal Title
  
  J Leukocyte Biol 75
  
  Pages: 434-442
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570507
[Journal Article] In situ demonstration of dendritic cell migration from rat intestine to mesenteric lymph nodes : relationships to maturation and role of chemokines.2004
- Author(s)
  Kobayashi H, Miura S, Nagata H, et al.
- Journal Title
  
  J Leukocyte Biol 75
  
  Pages: 434-442
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570507
[Journal Article] Exposure to fatty acids modulates interferon production by intraepithelial lymphocytes.2003
- Author(s)
  Hara Y, Miura S, Komoto S, Inamura T, Koseki S, Watanabe C, Hokari R, Tsuzuki Y, Ogino T, Nagata H, Hachimura S, Kaminogawa S, Ishii H.
- Journal Title
  
  Immunol Lett 86
  
  Pages: 139-148
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570507
[Journal Article] Alteration of intestinal intraepithelial lymphocytes and increased bacterial translocation in a murine model of cirrhosis.2003
- Author(s)
  Inamura T, Miura S, Tsuzuki Y, Nagata H. et al.
- Journal Title
  
  Immunol Lett 90
  
  Pages: 3-11
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570507
[Journal Article] Exposure to fatty acids modulates interferon production by intraepithelial lymphocytes.2003
- Author(s)
  Hara Y, Miura S, Komoto S, Nagata H, et al.
- Journal Title
  
  Immunol Lett 86:139-148,2003. 86
  
  Pages: 139-148
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570507
[Journal Article] Alteration of intestinal intraepithelial lymphocytes and increased bacterial translocation in a murine model of cirrhosis.2003
- Author(s)
  Inamura T, Miura S, Tsuzuki Y, Hara Y, Hokari R, Ogawa T, Teramoto K, Watanabe C, Kobayashi H, Nagata H, Ishii H.
- Journal Title
  
  Immunol Lett 90
  
  Pages: 3-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570507

1. SUEMATSU Makoto (00206385)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. SUZUKI Hidekazu (70255454)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
3. MINAMITANI Haruyuki (70051779)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. AKIBA Yasutada (50286449)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. NAKAMURA Masahiko (30155858)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. TANISHITA Kazuo (10101776)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. TANABE Masanobu (80051928)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KITAGAWA Yuko (20204878)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. MUKAI Makio (50101895)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SUDA Koichi (10348659)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 木村裕之 (00225054)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 今枝博之 (20203309)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 岡野栄之 (60160694)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 高木珠子 (90286469)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 大山隆史 (90338062)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

NAGATA Hiroshi 永田 博司

Research Projects

Research Products

Co-Researchers

癌転移を制御する所属リンパ節特異的微小環境の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Musashi-1をマーカーとした胃粘膜多能性幹細胞の同定と分離Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of novel trans-lymphatic chemotherapy targeted to micrometastasis in sentinel lymph nodes using a phospholipids polymer-paclitaxel conjugate

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of FX-activating molecules of convulsion-inducing lipoprotein purified from egg granulomas in Schistosoma mansoni-infected mice and of its inducing mechanism

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on vascular shutdown effects of carcinoma blood vessels and cytotoxic effects of carcinoma cells induced by photochemical reaction.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

MECHANISM OF REGULATING MOBILIZATION AND MIGRATION OF ANTIGEN PRESENTING CELLS DURING INFLAMMATIONPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Roles of ion transports in gastrointestinal mucosal defense, and their clinical application

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

CELL-TO-CELL INTERACTION IN THE MARGINALSINUS OF MESENTERIC LYMPH NODEPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The mechanism of Helicobacter pylori-induced gastric mucosal injury, involvement of heme iron and oxidative stress.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 分化阻止転写因子HESの発現をマーカーとした胃粘膜修復機構の検討。消化器病学の進歩2005モノグラフ、消化器病学のニューフロンテイア編2005

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Expression of Musashi-1 the rat stomach and changes during mucosal injury and restitution.2006

Author(s)

Journal Title

Data Source

[Journal Article] 胃癌は骨髄由来細胞から発生する(海外論文紹介)2006

Author(s)

Journal Title

Data Source

[Journal Article] Chronic allergy to dietary ovalbumin induces lymphocyte migration to rat small intestinal mucosa that is inhibited by MAdCAM-1.2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Limited capability of regional lymph nodes to eradicate metastatic cancer cells.2004

Author(s)

Journal Title

Data Source

NAGATA Hiroshi 永田博司