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SHIMIZU Hiroshi  清水 宏

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SHIMIZU H.  清水 宏

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Researcher Number 00146672
Other IDs
Affiliation (based on the past Project Information) *help 2021: 北海道大学, 医学研究院, 教授
2017 – 2019: 北海道大学, 医学研究院, 教授
2016: 北海道大学, 医学研究科, 教授
2013 – 2015: 北海道大学, 大学院医学研究科, 教授
2011 – 2015: 北海道大学, 医学(系)研究科(研究院), 教授 … More
2007 – 2012: Hokkaido University, Graduate of Medicine, Professor
2010: 北海道大学, 大学医学研究科, 教授
2007: Hokkaido University, Graduate School of Medicine, Professor
2006: Hokkaido University, Graduate School of Medicine, Professor, 大学院医学研究科, 教授
2006: 北海道大学, 大学院医学系研究科, 教授
2000 – 2005: 北海道大学, 大学院・医学研究科, 教授
2003: 北海道大学, 医学研究科, 教授
2001: Hokkaido University School of Medicine, Dermatology, Professor, 医学部, 教授
1999: Hokkaido Univ. School of Medicine, Dept.of Dermatology, Associate Professor, 医学部, 教授
1996 – 1999: 慶應義塾大学, 医学部, 助教授
1996: Keio Univ, Sch, Med., Associate Prof., 医学部・皮膚科, 助教授
1996: 慶應義塾大学, 医学部・皮膚科, 助教授
1995: 慶応義塾大学, 医学部, 講師
1995: Keio Univ., Sch.of Med., Assist.Pfor., 医学部, 講師
1995: 慶應義塾大学, 医学部・皮膚科, 専任講師
1994: Keio Univ.Sch.of Med., Ass.Prof.of Dermatology, 医学部・皮膚科, 講師
1993: 慶応義塾大学, 医学部・皮膚科, 助手
1993: Keio Univ.Sch.Med., Instructor, 医学部・皮膚科, 助手
1992: 慶応義塾大学, 医学部, 助手
1991 – 1992: 慶應義塾大学, 医学部, 助手
1990 – 1991: 慶應義塾大学, 医学部・皮膚科, 助手
1987: 慶應義塾大学, 医学部, 助手
1986: Department of Dermatology, Keio University School of Medicine, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Dermatology / Dermatology / Biological Sciences / Organ-based internal medicine and related fields
Except Principal Investigator
Dermatology / Dermatology / Orthopaedic surgery / Hygiene / Hygiene and public health / Basic Section 53050:Dermatology-related
Keywords
Principal Investigator
表皮水疱症 / VII型コラーゲン / ラミニン5 / 細胞・組織 / 基底膜 / epidermolysis bullosa / type VII collagen / 表皮 / 遺伝子導入 / 癌 … More / 遺伝子 / 出生前診断 / 創傷治癒 / 臨床 / 動物 / 免疫学 / 17型コラーゲン / LAMB3 / laminin 5 / basement membrane / 皮膚癌 / クローニング / 魚鱗癬 / 転移 / 接着分子 / 応用動物 / 生体機能利用 / バイオテクノロジー / 造血幹細胞移植 / transdifferentiation / 細胞療法 / モデルマウス / 皮膚基底膜 / Herlitz / 遺伝子診断 / prenatal diagnosis / laminin5 / DNA / 遺伝病 / 劣性栄養障害型 / Herlitz致死型 / 遺伝子治療 / 培養表皮シート / gene therapy / epidermis / 栄養障害型 / 重症 / 蛋白補充 / dystrophic / 免疫電顕 / Lowicryl / 凍結乾燥 / 凍結固定 / LH1,2 / CrB_3 / ダリエ病 / カルシウム濃度 / desmoplakin / plakoglobin / adherens junction / catenin / コンフォーカル顕微鏡 / 免疫電顕法 / 29A / 分子 / 表皮水痘症 / 遺伝子変異 / スプライシング / 扁平上皮癌 / 発癌機序 / 潰瘍形成 / 水疱型先天性魚鱗癬様紅皮症 / ケラチン / リポザイム / 19-DEJ-1抗原 / cDNAクローニング / cDNAサブトラクション法 / マイクロアレイ / 浸潤 / 自己免疫疾患 / 水疱性類天疱瘡 / ヒト化マウス / 疾患モデル動物 / CHO細胞 / NOD-Scid / 自己免疫性疾患 / 骨髄由来幹細胞 / 皮膚炎症・再生学 / 骨髄移植 / 骨髄由来細胞 / 幹細胞移植 / iPS細胞 / ドミナントネガティブ効果 / グリシン置換変異 / 7型コラーゲン / 皮膚細菌叢 / 細菌叢 / 致死型 / lethal type / DNA診断 / 表皮水泡症 / Laminin 5 / 遺伝子変異部位 / heteroduplex法 / COL7A1 / inherited diseases / DNA based diagnosis / skin disease / 培養表皮 / Vil型コラーゲン / SV40 / keratinocyte / gene transfection / プレクチン / ヘミデスモゾーム / 筋ジストロフィー / EB-MD症候群 / Plectin / hemidesmosome / muscular dystrophy / 表皮水庖症 / 表皮移植 / 補充治療 / 補充療法 / Wound healing / severe type / protein supplement / epidermal transplantation / 皮膚潰瘍 / wound healing / epidermolvsis bullosa / severe / protein therapy / gene transfer / skin ulcer / 内科 / 病理学 / immunology / animal / cell / tIssue / internal medicine / pathology / 復帰変異モザイク / 遺伝子編集 / CRISPR/Cas9 / 染色体組換え / 皮膚科学 / 先天性魚鱗癬 / 組換え / revertant mosaicism / 相同組換え … More
Except Principal Investigator
表皮水疱症 / 天疱瘡 / 遺伝子 / 遺伝子治療 / immunoelectron microscopy / VII型コラーゲン / ノックアウトマウス / 水疱性類天疱瘡 / 類天疱瘡 / 免疫電顕 / epidermolysis bullosa / デスモグレイン / 魚鱗癬 / 基底膜 / 動物モデル / 17型コラーゲン / 自己免疫性水疱症 / Desmoglein / ラミニン5 / ichthyosis / gene therapy / 線維芽細胞 / 角化 / 自己免疫性疾患 / トランスジェニックマウス / 環境 / アトピー性皮膚炎 / 衛生 / 線状IgA皮膚症 / bullous pemphigoid / 凍結固定 / 凍結置換 / cryosubstitution / 出生前診断 / 先天性表皮水疱症 / GB3 / LH7.2 / 19-DEJ-1 / prenatal diagnosis / カドヘリン / Pemphigus / B cell / 自己免疫性皮膚疾患 / Animal model / トランスグルタミナーゼ / cornified cell envelope / BPAG2 / type VII collagen / laminin 5 / 変異 / 幹細胞 / mutation / 腱 / 靭帯 / マトリクス / BP180 / ABCA12 / 皮膚病理学 / 細胞・組織 / 超微形態 / 免疫 / 動物 / 胎児治療 / VII型ゴラーゲン / マウスモデル / 自己免疫 / 皮膚 / 抗体 / 後天性表皮水疱症 / 皮膚炎症 / 再生学 / 皮膚生理学 / 皮膚性理学 / 自己免疫疾患 / ヒト化マウス / 疾患モデル動物 / IgG1/IgG4 / 抗体サブクラス / 補体活性化 / アレルギー・喘息 / フィラグリン遺伝子 / 自宅環境 / ダスト / ダニアレルゲン / 出生コーホート / 遺伝的素因 / 環境用要因 / プラスミン / COL17 / 7型コラーゲン / 抗表皮細胞間抗体 / デスモゾーム / モノクローナル抗体 / デスモプラキン / 遺伝性家族性水疱症 / 免疫ブロット法 / 免疫沈降法 / 抗表皮基底膜部抗体 / hereditary and familial bullous diseases / autoimmune bullous diseases / immunoblotting / immunoprecipitation / 皮膚水疱症 / 金コロイド / イメージアサライザー / ヘミデスモゾーム / colloidal gold / cryofixation / image analyzer / hemidesmosome / 胎児皮膚生検 / 電顕 / 遺伝相談 / fetal skin biopsy / electron microscopy / 疱疹状皮膚炎 / デスモソーム / 分子生物学 / リコンビナント蛋白 / 自己抗原 / Autoimmune bullous disease, / Pemphigus, / Bullous pemphigoid, / Dermatitis herpetiformis, / Desmosome, / Molecular biology, / Desmoglein, / Recombinant protein / 尋常性天疱瘡 / 落葉状天疱瘡 / 凍結同定 / クリオウルトラ切片 / クリオウルトラ切手 / セドヘリン / crvoultramicrotomy / crvofixation / cadherin / B細胞 / 疾患特異的治療法 / 組換え毒素 / 細胞接着 / Autoimmune disease / Disease-specific therapy / Recombinant toxin / Cadherin / Cell adhesion / 遺伝性皮膚疾患 / 表皮シート / 遺伝子解析 / 自己免疫皮膚疾患 / Autoimmune / Inherited skin disease / Laminin 5 / Type VII collagen / Epidermal sheets / Gene therapy / 自己抗体 / 免疫寛容 / 抗体産生B細胞 / Autoimmune diseases / Tolerance / Autoantibody / Knochout mouse / 道化師様魚鱗癬 / 非水泡型魚鱗癬様紅皮症 / 葉状魚鱗癬 / セル・エンベロープ / ロリクリン / 遺伝子異変 / 非水疱型魚鱗癬様紅皮症 / gene mutation / genodermatosis / non-bullous congenital ichthyosiform erthroderma / transglutaminase 1 / 免疫電顕法 / 遺伝子変異 / basement membrane / mutation analysis / 栄養障害型 / 重症 / 蛋白補充 / 遺伝子導入 / 真皮 / dystrophic / severe / protein therapy / gene transfer / dermis / 毛包 / バルジ / 魚鱗癬症候群 / 漁鱗癬 / マウス / hair follicle / bulge / stem cell / ichthyosis syndrome / transglutaminase / 生体軟組織 / リモデリング(再構築) / 除負荷 / 分子制御 / 徐負荷 / 靱帯 / Soft tissues / Tendon / Ligament / Matrix / Remodeling / Fibroblast / Stress deprivation / Molecular control / 再構築 / コラゲン / tendon / ligament / matrix / remodeling / fibroblast / collagen / エピトープ / デコイ / XVII型コラーゲン / 水疱性天疱瘡 / pemphigoid / knockout mouse / transgenic mouse / epitope / decoy / typeXVII collagen / 皮膚バリア / harlequin ichthyosis / skin barrier / 水疱症 / 細胞表面マーカー / 浸潤細胞 / Pemphigoid / pemphigus / ノンコーディングRNA / 表皮 / 分化 / 皮膚病態学 / 瘢痕型脱毛症 / 創傷治癒 / 発癌 / 7型コラーゲン / 有棘細胞癌 / 皮膚腫瘍学 / 環境化学物質 / ハウスダスト / 酸化ストレスマーカー / フィラグリン / 遺伝子発現 / バイオマーカー / 毛孔性紅色粃糠疹5型 / 復帰変異モザイク / revertant mosaicism / 自己炎症性疾患 / 自己炎症性皮膚疾患 / 自己炎症性角化症 / 自然治癒 / 相同組換え Less
  • Research Projects

    (60 results)
  • Research Products

    (424 results)
  • Co-Researchers

    (108 People)
  •  Revertant mosaicism in autoinflammatory skin diseases

    • Principal Investigator
      Nomura Toshifumi
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 53050:Dermatology-related
    • Research Institution
      University of Tsukuba
      Hokkaido University
  •  The critical role for fibroblast in RDEB-SCC patients

    • Principal Investigator
      Hata Hiroo
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Hokkaido University
  •  Establishment of epidermolysis bullosa model mouse with revertant mosaicism and its treatmentPrincipal Investigator

    • Principal Investigator
      Shimizu Hiroshi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Dermatology
    • Research Institution
      Hokkaido University
  •  Revertant mosaicism in congenital ichthyosesPrincipal Investigator

    • Principal Investigator
      Shimizu Hiroshi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Challenging Research (Pioneering)
    • Research Field
      Organ-based internal medicine and related fields
    • Research Institution
      Hokkaido University
  •  Establishment of cicatricial alopecia animal models

    • Principal Investigator
      Nakamura Hideki
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Hokkaido University
  •  Non-coding RNAs in keratinization

    • Principal Investigator
      Nomura Toshifumi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Hokkaido University
  •  Treatment of epidermolysis bullosa with revertant keratinocyte-derived iPS cells

    • Principal Investigator
      Fujita Yasuyuki
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Hokkaido University
  •  FLG variance and environmnetal chemical exposure to atopic dermatitis among school children

    • Principal Investigator
      Atsuko Araki
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hygiene and public health
    • Research Institution
      Hokkaido University
  •  Elucidating roles of plasmin in blister formation of bullous pemphigoid

    • Principal Investigator
      Nakamura Hideki
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Hokkaido University
  •  Novel therapies for recessive dystrophic epidermolysis bullosa targeting at the COL7A1 promoter

    • Principal Investigator
      ARITA KEN
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Hokkaido University
  •  Modulation of skin microbiota through basememt membranePrincipal Investigator

    • Principal Investigator
      SHIMIZU Hiroshi
    • Project Period (FY)
      2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Dermatology
    • Research Institution
      Hokkaido University
  •  Investigation of hematopoietic stem cell transplantation for epidermolysis bullosaPrincipal Investigator

    • Principal Investigator
      SHIMIZU Hiroshi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Dermatology
    • Research Institution
      Hokkaido University
  •  Environmental and Genetic risk factors of Atopic dermatitis among 7-year old children in birth cohort

    • Principal Investigator
      ARAKI Atsuko
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hygiene
    • Research Institution
      Hokkaido University
  •  Generation of dominant dystrophic epidermolysis bullosa model mice using humanized COL7 micePrincipal Investigator

    • Principal Investigator
      SHIMIZU Hiroshi
    • Project Period (FY)
      2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Dermatology
    • Research Institution
      Hokkaido University
  •  Development of novel treatment targeting complement for bullous pemphigoid

    • Principal Investigator
      SHIBAKI Akihiko
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Hokkaido University
  •  Development of stem cell therapy for epidermolysis bullosa model mice expressing humanized dermo-epidermal junctional proteinPrincipal Investigator

    • Principal Investigator
      SHIMIZU Hiroshi
    • Project Period (FY)
      2011
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Dermatology
    • Research Institution
      Hokkaido University
  •  新規表皮水疱症モデルマウスに対する骨髄移植療法の試みPrincipal Investigator

    • Principal Investigator
      清水 宏
    • Project Period (FY)
      2010
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Dermatology
    • Research Institution
      Hokkaido University
  •  Analysis of pathomechanisms of bullous pemphigoid and development of novel therapy by using humanized active mouse modelPrincipal Investigator

    • Principal Investigator
      SHIMIZU Hiroshi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Dermatology
    • Research Institution
      Hokkaido University
  •  皮膚癌の浸潤、転移能における表皮接着分子の直接的関与についての解析Principal Investigator

    • Principal Investigator
      清水 宏
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Hokkaido University
  •  Innovation of novel treatment and fetal therapy for ichthyosis

    • Principal Investigator
      AKIYAMA Masashi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Dermatology
    • Research Institution
      Nagoya University
      Hokkaido University
  •  Animal model for dystrophic epidermolysis bullosa and acquired epidermolysis bullosa using genetically engineered mice of type VII collagen

    • Principal Investigator
      SAWAMURA Daisuke
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Dermatology
    • Research Institution
      Hirosaki University
  •  Regenerative medical therapy using bone marrow derived cells

    • Principal Investigator
      ABE Riichiro
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Hokkaido University
  •  17型コラーゲンectodomain sheddingの生理的機能の解明Principal Investigator

    • Principal Investigator
      清水 宏
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Hokkaido University
  •  Objective Evaluation Method of Genetic Treatment for Epidermolysis bullosa

    • Principal Investigator
      NAKAMURA Hideki
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Hokkaido University
  •  母体由来自己抗体を用いた水疱性類天疱瘡の新規モデルPrincipal Investigator

    • Principal Investigator
      清水 宏
    • Project Period (FY)
      2007
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Dermatology
    • Research Institution
      Hokkaido University
  •  皮膚癌の浸潤、転移能における表皮接着分子の直接的関与についての解析Principal Investigator

    • Principal Investigator
      清水 宏
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Hokkaido University
  •  Pathogenecity of autoantibody in bullous pemphigoid and development of epitope-decoy therapy

    • Principal Investigator
      SAWAMURA Daisuke
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Dermatology
    • Research Institution
      Hirosaki University
  •  Development of a new therapy of severe ichthyosis caused by ABCA12 mutations

    • Principal Investigator
      MASASHI Akiyama
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Dermatology
    • Research Institution
      Hokkaido University
  •  皮膚癌の浸潤、転移能における表皮接着分子の直接的関与についての解析Principal Investigator

    • Principal Investigator
      清水 宏
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Hokkaido University
  •  Study of the pathologic mechanisms and development of the novel therapeutic strategy using bullous pemphigoid model micePrincipal Investigator

    • Principal Investigator
      SHIMIZU Hiroshi
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Dermatology
    • Research Institution
      Hokkaido University
  •  皮膚癌の浸潤、転移能における表皮接着分子の直接的関与についての解析Principal Investigator

    • Principal Investigator
      清水 宏
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Hokkaido University
  •  Development of a new strategy for gene therapy of autosomal recessive congenital ichthyosis by gene transfer to the bulge stem cells

    • Principal Investigator
      AKIYAMA Masashi
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Dermatology
    • Research Institution
      Hokkaido University
  •  Clarification of Mechanism of the Tendon/Ligament Matrix Remodeling Induced by Various Mesenchymal Cells and Its Molecular Control

    • Principal Investigator
      YASUDA Kazunori
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Hokkaido University
  •  THE SIGNIFICANCE OF GENE EXPRESSION IN EXTRINSIC FIBROBLASTS IN THE REMODELING OF THE TENDON MATRIX

    • Principal Investigator
      TOHYAMA Harukazu
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  皮膚癌の浸潤,転移能における表皮接着分子の直接的関与についての解析Principal Investigator

    • Principal Investigator
      清水 宏
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Hokkaido University
  •  19-DEJ-1抗原のcDNAクローニングPrincipal Investigator

    • Principal Investigator
      清水 宏
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Dermatology
    • Research Institution
      Hokkaido University
  •  Development of a new treatment strategy for wound healing using recombinant type VII collagenPrincipal Investigator

    • Principal Investigator
      SHIMIZU Hiroshi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Dermatology
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  Establishment of a system in which type VII collagen and laminin 5 or their genes are continuously delivered from the dermal side to the basement membrane zone

    • Principal Investigator
      SAWAMURA Daisuke
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Dermatology
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  COL7A1遺伝子変異と扁平上皮癌の発症および予後との関連の解明Principal Investigator

    • Principal Investigator
      清水 宏
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Hokkaido University
  •  変異m-RNAの選択能破壊による水泡型先天性魚鱗癬様紅皮症の新しい治療法の開発Principal Investigator

    • Principal Investigator
      清水 宏
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Dermatology
    • Research Institution
      Hokkaido University
  •  29Aモノクローナル抗体が認識する新しい表皮基底膜分子の同定Principal Investigator

    • Principal Investigator
      清水 宏
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Dermatology
    • Research Institution
      Hokkaido University
  •  Development of a novel therapy for epidermolysis bullosa using recombinantPrincipal Investigator

    • Principal Investigator
      SHIMIZU Hiroshi
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Dermatology
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  Elucidation of the pathomechanism of epidermolysis bullosa - muscular dystrophy syndromePrincipal Investigator

    • Principal Investigator
      SHIMIZU Hiroshi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Dermatology
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  Immunoelectron microscopic analysis of basement membrane components in type VII collagen knockout skin

    • Principal Investigator
      ISHIKO Akira
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Keio University
  •  培養表皮細胞システムを用いたダリエ病の病因蛋白の推定Principal Investigator

    • Principal Investigator
      清水 宏
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Dermatology
    • Research Institution
      Hokkaido University
  •  Development of novel therapy against bullous diseases

    • Principal Investigator
      NISHIKAWA Takeji
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Dermatology
    • Research Institution
      Keio University
  •  Development of novel mouse model for autoimmune diseases using autoantigen knockout mice

    • Principal Investigator
      NISHIKAWA Takeji
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Dermatology
    • Research Institution
      Keio University
  •  Elucidation of Pathogenetic Mechanisms of Severe Ichthyoses and Establishment of New Method for the Diagnosis and Prenatal Disease Detection

    • Principal Investigator
      NISHIKAWA Takeji
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Dermatology
    • Research Institution
      Keio University
  •  Gene therapy for epidermolysis bullosa using cultured keratinocytes sheetPrincipal Investigator

    • Principal Investigator
      SHIMIZU Hiroshi
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Dermatology
    • Research Institution
      Keio University
  •  Development of antigen-specific B cell elimination by recombinant toxins in autoimmune diseases

    • Principal Investigator
      AMAGAI Masayuki
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Dermatology
    • Research Institution
      Keio University
  •  Mutation detection and DNA based prenatal diagnosis in Japanese patients with epidermolysis bullosaPrincipal Investigator

    • Principal Investigator
      SHIMIZU Hiroshi
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Dermatology
    • Research Institution
      Keio University
  •  Molecular basis of Japanese with Herlitz epidermolysis bullosa and Its application to the diagnosis and prenatal diagnosisPrincipal Investigator

    • Principal Investigator
      SHIMIZU Hiroshi
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Dermatology
    • Research Institution
      Keio University
  •  皮膚癌による基底膜構造の破壊と予後との相関Principal Investigator

    • Principal Investigator
      清水 宏
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Keio University
  •  Basic studies for the pathogenesis and diagnosis of the autoimmune bullous diseases

    • Principal Investigator
      NISHIKAWA Takeji
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Keio Gijuku University School of Medicine
  •  Clarification of pathogenesis in pemphigus : Establishment of new techniques for diagnosis.

    • Principal Investigator
      NISHIKAWA Takeji
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Dermatology
    • Research Institution
      Keio University
  •  Establishment of prenatal diagnosis of epidermolysis bullosa in Japan

    • Principal Investigator
      NISHIKAWA Takeji
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Dermatology
    • Research Institution
      Keio Gijuku University
  •  Application of up-to date immunoelectron microscopy for the study of pathogenesis of skin blistering disease.

    • Principal Investigator
      NISHIKAWA Takeji
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Dermatology
    • Research Institution
      Keio University
  •  Basic studies for the diagnosis of bullous diseases having pathologic changes at the basement membrane zone

    • Principal Investigator
      NISHIKAWA Takeji
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Keio Gijuku University
  •  デスモゾーム蛋白と天疱瘡の抗原物質の関連に関する研究

    • Principal Investigator
      NISHIKAWA Takeji
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Keio University
  •  Role of cutaneous infiltrates in pemphigoid and pemphigus.

    • Principal Investigator
      NISHIKAWA T.
    • Project Period (FY)
      1985 – 1986
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Dermatology
    • Research Institution
      School of Medicine, Keio University

All 2021 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation Book

  • [Book] あたらしい皮膚科学第3版2018

    • Author(s)
      清水宏
    • Total Pages
      640
    • Publisher
      中山書店
    • ISBN
      4521745814
    • Data Source
      KAKENHI-PROJECT-15H04780
  • [Book] "Innovative Medicine Basic Research and Development", Doxycycline-Inducible Autoimmune Blistering Skin Disease Model2015

    • Author(s)
      Nishie W, Shimizu H (eds: Nakao K, Minato N, Uemoto S)
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-15H04780
  • [Book] 1冊でわかる最新皮膚科治療2013

    • Author(s)
      五十嵐敦之(ゲスト編集), 宮地良樹(常任編集), 清水宏(常任編集)
    • Total Pages
      328
    • Publisher
      文光堂
    • Data Source
      KAKENHI-PROJECT-24390152
  • [Book] Hailey-Hailey病. In : 塩原哲夫,宮地良樹,渡辺晋一,佐藤伸一 (eds.) : 今日の皮膚疾患治療指針2012

    • Author(s)
      清水宏
    • Publisher
      医学書院
    • Data Source
      KAKENHI-PROJECT-24390152
  • [Book] Treatment of Skin Disease 3rd Edition-Comprehensive Therapeutic Strategies2010

    • Author(s)
      Tsuji-Abe, Y., Shimizu, H.
    • Total Pages
      2
    • Publisher
      Mosby-Elsevier
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Book] からだの科学2009

    • Author(s)
      新熊悟, 夏賀健, 清水宏
    • Total Pages
      5
    • Publisher
      日本評論社
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Book] 第2版 皮膚疾患診療 実践ガイド 膿疱を生じる疾患2009

    • Author(s)
      守内玲寧, 芝木晃彦, 清水宏
    • Total Pages
      1
    • Publisher
      文光堂
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Book] 臨床検査データブック2009-20102009

    • Author(s)
      清水宏
    • Total Pages
      2
    • Publisher
      医学書院
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Book] 皮膚疾患最新の治療2009-20102009

    • Author(s)
      清水宏
    • Total Pages
      1
    • Publisher
      南江堂
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Book] 第2版 皮膚疾患診療 実践ガイド 水疱を生じる疾患2009

    • Author(s)
      守内玲寧, 芝木晃彦, 清水宏
    • Total Pages
      1
    • Publisher
      文光堂
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Book] 皮膚科診療カラーアトラス大系2009

    • Author(s)
      乃村俊史, 清水宏
    • Total Pages
      4
    • Publisher
      講談社
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Book] 第2版 皮膚疾患診療 実践ガイド 皮膚科遺伝相談2009

    • Author(s)
      守内玲寧, 芝木晃彦, 清水宏
    • Total Pages
      2
    • Publisher
      文光堂
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Altered replication stress response due to CARD14 mutations promotes recombination-induced revertant mosaicism.2021

    • Author(s)
      Miyauchi Toshinari、Suzuki Shotaro、Takeda Masae、Peh Jin Teng、Aiba Masayuki、Natsuga Ken、Fujita Yasuyuki、Takeichi Takuya、Sakamoto Taiko、Akiyama Masashi、Shimizu Hiroshi、Nomura Toshifumi
    • Journal Title

      Am J Hum Genet.

      Volume: 108 Pages: 1026-1039

    • DOI

      10.1016/j.ajhg.2021.04.021

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K21591, KAKENHI-PROJECT-19H03679, KAKENHI-PROJECT-18K16058
  • [Journal Article] Electron Microscopic and Immunohistochemical Findings of the Epidermal Basement Membrane in Two Families with Nail-patella Syndrome.2019

    • Author(s)
      Shinkuma S、Nakamura H、Maehara M、Takashima S、Nomura T、Fujita Y、Hasegawa S、Sato-Matsumura K、Abe R、Shimizu H
    • Journal Title

      Acta Dermato-Venereologica

      Volume: 99(12) Pages: 1110-1115

    • DOI

      10.2340/00015555-3318

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08764, KAKENHI-PROJECT-17H01572, KAKENHI-PROJECT-17H05089
  • [Journal Article] The direct binding of collagen XVII and collagen IV is disrupted by pemphigoid autoantibodies2019

    • Author(s)
      Kamaguchi Mayumi、Iwata Hiroaki、Nishie Wataru、Toyonaga Ellen、Ujiie Hideyuki、Natsuga Ken、Kitagawa Yoshimasa、Shimizu Hiroshi
    • Journal Title

      Lab Invest

      Volume: 99 Pages: 48-57

    • DOI

      10.1038/s41374-018-0113-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10120, KAKENHI-PROJECT-16K10141, KAKENHI-PROJECT-17K16317
  • [Journal Article] Type XVII collagen coordinates proliferation in the interfollicular epidermis2019

    • Author(s)
      Watanabe M, Natsuga K, Nishie W, Kobayashi Y, Donati G, Suzuk Si, Fujimura Y, Tsukiyama T, Ujiie H, Shinkuma S, Nakamura H, Murakami M, Ozaki M, Nagayama M, Watt F and Shimizu H
    • Journal Title

      Bioscience, Biotechnology, and Biochemistry

      Volume: 6:e26635 Pages: 2110-2120

    • DOI

      10.7554/elife.26635

    • NAID

      120006337772

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K07105, KAKENHI-PROJECT-16K10120, KAKENHI-PROJECT-17K16317, KAKENHI-PROJECT-16H03949, KAKENHI-PROJECT-17H04022
  • [Journal Article] Efficient Gene Reframing Therapy for Recessive Dystrophic Epidermolysis Bullosa with CRISPR/Cas92019

    • Author(s)
      Takashima Shota、Shinkuma Satoru、Fujita Yasuyuki、Nomura Toshifumi、Ujiie Hideyuki、Natsuga Ken、Iwata Hiroaki、Nakamura Hideki、Vorobyev Artem、Abe Riichiro、Shimizu Hiroshi
    • Journal Title

      Journal of Investigative Dermatology

      Volume: in press Pages: 1711-1721

    • DOI

      10.1016/j.jid.2019.02.015

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H05089, KAKENHI-PROJECT-16K10120, KAKENHI-PROJECT-19K08764, KAKENHI-PROJECT-17H01572
  • [Journal Article] A recurrent subcutaneous tumour of the thumb: a case of a capicua transcriptional repressor ( CIC )‐rearranged sarcoma2019

    • Author(s)
      Mizukami T.、Yanagi T.、Kitamura S.、Narahira A.、Maeda T.、Hata H.、Takakuwa E.、Doi K.、Sugita S.、Hasegawa T.、Ikenaga H.、Shimizu H.
    • Journal Title

      Journal of the European Academy of Dermatology and Venereology

      Volume: 34

    • DOI

      10.1111/jdv.15910

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K08259, KAKENHI-PROJECT-17K10223
  • [Journal Article] Somatic recombination underlies frequent revertant mosaicism in loricrin keratoderma.2019

    • Author(s)
      Suzuki Shotaro、Nomura Toshifumi、Miyauchi Toshinari、Takeda Masae、Fujita Yasuyuki、Nishie Wataru、Akiyama Masashi、Ishida-Yamamoto Akemi、Shimizu Hiroshi
    • Journal Title

      Life Sci Alliance

      Volume: 2

    • DOI

      10.26508/lsa.201800284

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K19531, KAKENHI-PROJECT-17H06271, KAKENHI-PROJECT-18K19540
  • [Journal Article] Epidermal aspects of type VII collagen: Implications for dystrophic epidermolysis bullosa and epidermolysis bullosa acquisita2018

    • Author(s)
      Watanabe Mika、Natsuga Ken、Shinkuma Satoru、Shimizu Hiroshi
    • Journal Title

      The Journal of Dermatology

      Volume: 45 Pages: 515-521

    • DOI

      10.1111/1346-8138.14222

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H01572, KAKENHI-PROJECT-17H05089, KAKENHI-PROJECT-17K16317
  • [Journal Article] Successful treatment of hidradenitis suppurativa with rituximab for a patient with idiopathic carpotarsal osteolysis and chronic active antibody-mediated rejection.2018

    • Author(s)
      Takahashi K, Yanagi T, Kitamura S, Hata H, Imafuku K, Iwami D, Hotta K, Morita K, Shinohara N, Shimizu H.
    • Journal Title

      J Dermatol.

      Volume: 45

    • DOI

      10.1111/1346-8138.14144

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10223
  • [Journal Article] Gentamicin-Induced Readthrough and Nonsense-Mediated mRNA Decay of SERPINB7 Nonsense Mutant Transcripts2018

    • Author(s)
      Ohguchi Yuka、Nomura Toshifumi、Suzuki Shotaro、Takeda Masae、Miyauchi Toshinari、Mizuno Osamu、Shinkuma Satoru、Fujita Yasuyuki、Nemoto Osamu、Ono Kota、McLean W.H. Irwin、Shimizu Hiroshi
    • Journal Title

      Journal of Investigative Dermatology

      Volume: 138 Pages: 836-843

    • DOI

      10.1016/j.jid.2017.10.014

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09738, KAKENHI-PROJECT-18K19531
  • [Journal Article] Filaggrin gene mutations may influence the persistence of food allergies in Japanese primary school children.2018

    • Author(s)
      Kono M.、Akiyama M.、Inoue Y.、Nomura T.、Hata A.、Okamoto Y.、Takeichi T.、Muro Y.、McLean W.H.I.、Shimizu H.、Sugiura K.、Suzuki Y.、Shimojo N.
    • Journal Title

      Br J Dermatol

      Volume: - Pages: 190-191

    • DOI

      10.1111/bjd.16375

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04780, KAKENHI-PROJECT-18K08281, KAKENHI-PROJECT-18K19531, KAKENHI-PROJECT-15H04886
  • [Journal Article] The development of induced pluripotent stem cell-derived mesenchymal stem/stromal cells from normal human and RDEB epidermal keratinocytes2018

    • Author(s)
      Nakayama Chihiro、Fujita Yasuyuki、Matsumura Wakana、Ujiie Inkin、Takashima Shota、Shinkuma Satoru、Nomura Toshifumi、Abe Riichiro、Shimizu Hiroshi
    • Journal Title

      Journal of Dermatological Science

      Volume: 91 Pages: 301-310

    • DOI

      10.1016/j.jdermsci.2018.06.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K19531, KAKENHI-PROJECT-17H01572, KAKENHI-PROJECT-17H05089
  • [Journal Article] Establishment of integration-free induced pluripotent stem cells from human recessive dystrophic epidermolysis bullosa keratinocytes.2018

    • Author(s)
      Matsumura Wakana、Fujita Yasuyuki、Nakayama Chihiro、Shinkuma Satoru、Suzuki Shotaro、Nomura Toshifumi、Abe Riichiro、Shimizu Hiroshi
    • Journal Title

      Journal of Dermatological Science

      Volume: 89 Pages: 263-271

    • DOI

      10.1016/j.jdermsci.2017.11.017

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H05089, KAKENHI-PROJECT-15K09753, KAKENHI-PROJECT-17H01572
  • [Journal Article] Chromosomal inversions as a hidden disease-modifying factor for somatic recombination phenotypes2018

    • Author(s)
      Nomura T, Suzuki S, Miyauchi T, Takeda M, Shinkuma S, Fujita Y, Nishie W, Akiyama M, Shimizu H
    • Journal Title

      JCI Insight

      Volume: 3

    • DOI

      10.1172/jci.insight.97595

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H06271, KAKENHI-PROJECT-15K09738, KAKENHI-PROJECT-18K19540
  • [Journal Article] Filaggrin Mutation in Korean Patients with Atopic Dermatitis2017

    • Author(s)
      On Hye Rang、Lee Sang Eun、Kim Song-Ee、Hong Won Jin、Kim Hyun Jung、Nomura Toshifumi、Suzuki Shotaro、Shimizu Hiroshi、Kim Soo-Chan
    • Journal Title

      Yonsei Medical Journal

      Volume: 58 Pages: 395-395

    • DOI

      10.3349/ymj.2017.58.2.395

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04780, KAKENHI-PROJECT-15K09738
  • [Journal Article] Loss of interaction between plectin and type XVII collagen results in epidermolysis bullosa simplex2017

    • Author(s)
      Natsuga K, Nishie W, Nishimura M, Shinkuma S, Watanabe M, Izumi K, Nakamura H, Hirako Y, Shimizu H
    • Journal Title

      HUMAN MUTATION

      Volume: 38 Pages: 1666-1670

    • DOI

      10.1002/humu.23344

    • NAID

      120006540047

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10120, KAKENHI-PROJECT-17K10207, KAKENHI-PROJECT-17K16317
  • [Journal Article] A severe case of X-linked ichthyosis showing palmar hyperlinearity withoutFLGmutations2017

    • Author(s)
      Katayama S, Nomura T, Muramatsu K, Takeda M, Miyauchi T, Suzuki S, Shinkuma S, Fujita Y, Iwata H, Shimizu H
    • Journal Title

      Journal of the European Academy of Dermatology and Venereology

      Volume: 31

    • DOI

      10.1111/jdv.13863

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09738, KAKENHI-PROJECT-15H04780
  • [Journal Article] The first familial cases of epidermolysis bullosa simplex, generalized severe with p.Asn176Ser in KRT5 revealing the clinical chronology2017

    • Author(s)
      Sugai T, Shinkuma S, Inafuku K, Takashima S, Nomura T, Fujita Y, Nakamura H, Shimizu H
    • Journal Title

      J Eur Acad Dermatol Venereol

      Volume: in press

    • DOI

      10.1111/jdv.14036

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-16K15540, KAKENHI-PROJECT-16K10120
  • [Journal Article] Identification of SERPINB7 mutations in Korean patients with Nagashima-type palmoplantar keratosis2017

    • Author(s)
      On Hye Rang、Lee Sang Eun、Nomura Toshifumi、Miyauchi Toshinari、Suzuki Shotaro、Shimizu Hiroshi、Kim Soo-Chan
    • Journal Title

      Journal of Dermatology

      Volume: 44 Pages: 840-841

    • DOI

      10.1111/1346-8138.13545

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09738
  • [Journal Article] Deficient stratum corneum intercellular lipid in a Japanese patient with lamellar ichthyosis with a homozygous deletion mutation in SDR9C7.2017

    • Author(s)
      Takeichi T, Nomura T, Takama H, Kono M, Sugiura K, Watanabe D, Shimizu H, Simpson MA, McGrath JA, Akiyama M.
    • Journal Title

      British Journal of Dermatology

      Volume: 印刷中

    • DOI

      10.1111/bjd.15315

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04887, KAKENHI-PROJECT-16K15547, KAKENHI-PROJECT-16K19717, KAKENHI-PROJECT-17K16355, KAKENHI-PROJECT-15K09738
  • [Journal Article] A case of recessive dystrophic epidermolysis bullosa with a novel c.6885_6898del14 mutation in the COL7A1 gene2017

    • Author(s)
      Shinkuma S, Masunaga T, Miyawaki S, Takashima S, Natsuga K, Nomura T, Fujita Y, Nakamura H, Shimizu H
    • Journal Title

      Journal of Dermatological Science

      Volume: 88 Pages: 139-141

    • DOI

      10.1016/j.jdermsci.2017.03.022

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10120, KAKENHI-PROJECT-17K16317, KAKENHI-PROJECT-16K15540
  • [Journal Article] Compound heterozygotes for filaggrin gene mutations do not always show severe atopic dermatitis2017

    • Author(s)
      Sekiya, A., M. Kono, H. Tsujiuchi, T. Kobayashi, T. Nomura, M. Kitakawa, N. Suzuki, K. Yamanaka, H. Sueki, W. H. McLean, H. Shimizu and M. Akiyama
    • Journal Title

      Journal of the European Academy of Dermatology and Venereology

      Volume: 31 Pages: 158-162

    • DOI

      10.1111/jdv.13871

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461690, KAKENHI-PROJECT-15H04780, KAKENHI-PROJECT-15K09738
  • [Journal Article] アトピー性皮膚炎診療ガイドライン2016年版.2017

    • Author(s)
      藤田靖幸, 清水宏
    • Journal Title

      今日の治療指針 2017

      Volume: - Pages: 1928-1932

    • Data Source
      KAKENHI-PROJECT-15H04780
  • [Journal Article] Rapid remission of severe pain from livedoid vasculopathy by apixaban2016

    • Author(s)
      Yamaguchi Y, Nakazato S, Izumi K, Ieko M, Nomura T, Shimizu H
    • Journal Title

      J Eur Acad Dermatol Venereol

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H04780
  • [Journal Article] Epitope-dependent pathogenicity of Abs targeting a major bullous pemphigoid autoAg collagen XVII/BP1802016

    • Author(s)
      Wada M, Nishie W*, Ujiie H, Izumi K, Iwata H, Natsuga K, Nakamura H, Kitagawa Y, Shimizu H:
    • Journal Title

      J Invest Dermatol

      Volume: 136 Pages: 938-946

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10120
  • [Journal Article] Generalized acute subcutaneous edema as a rare cutaneous manifestation of severe dermatomyositis2016

    • Author(s)
      Watanabe M, Natsuga K, Arita K, Abe R, Shimizu H.
    • Journal Title

      J Eur Acad Dermatol Venereol

      Volume: in press

    • DOI

      10.1111/jdv.13460

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461681, KAKENHI-PROJECT-15K19668
  • [Journal Article] Warts in toe webs associated with human papillomavirus type 7: A specific cutaneous manifestation of this type?2016

    • Author(s)
      Miyauchi T, Moriuchi R, Hamade Y, Suzuki S, Nomura T, Shimizu S
    • Journal Title

      Br J Dermatol

      Volume: 174 Pages: 678-681

    • DOI

      10.1111/bjd.14190

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H04780
  • [Journal Article] Massive petechiae as an initial symptom of Waldenstrom’s macroglobulinaemia2016

    • Author(s)
      Shiba K, Abe R, Miyauchi T, Nomura T, Kondo T, Shimizu H
    • Journal Title

      Int J Dermatol

      Volume: in press

    • DOI

      10.1111/ijd.13189

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H04780
  • [Journal Article] Nodular morphoea: a first case associated with linear morphoea.2016

    • Author(s)
      Nakazato S, Nomura T, Yamane N, Shinkuma S, Natsuga K, Fujita Y, Arita K, Shimizu H
    • Journal Title

      European Journal of Dermatology

      Volume: 26 Pages: 95-96

    • DOI

      10.1684/ejd.2015.2656

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H04780, KAKENHI-PROJECT-25461681, KAKENHI-PROJECT-15K19668
  • [Journal Article] Extracellular cleavage of collagen XVII is essential for correct cutaneous basement membrane formation2016

    • Author(s)
      Nishimura M, Nishie W, Shirafuji Y, Shinkuma S, Natsuga K, Nakamura H, Sawamura D, Iwatsuki K, Shimizu H
    • Journal Title

      Hum Mol Genet.

      Volume: 15;25(2) Pages: 328-329

    • DOI

      10.1093/hmg/ddv478

    • NAID

      120005868259

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25461661, KAKENHI-PROJECT-15K15409, KAKENHI-PROJECT-24390274, KAKENHI-PROJECT-26293254, KAKENHI-PROJECT-15K19668, KAKENHI-PROJECT-16K10120, KAKENHI-PROJECT-15KK0289
  • [Journal Article] RNA recognition motif of LEMD3 as a key player in the pathogenesis of Buschke-Ollendorff syndrome2016

    • Author(s)
      Takashima S, Fujita Y, Suzuki S, Saito N, Shinkuma S, Nomura T, Shimizu H
    • Journal Title

      J Dermatol Sci

      Volume: 81 Pages: 205-208

    • DOI

      10.1016/j.jdermsci.2015.12.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H04780
  • [Journal Article] Erythrokeratoderma variabilis caused by p.Gly45Glu in connexin 31: the importance of the first extracellular loop glycine residue for gap junction function.2016

    • Author(s)
      Takeichi T, Sugiura K, Hsu CK, Nomura T, Takama H, Simpson MA, Shimizu H, McGrath JA, Akiyama M.
    • Journal Title

      Acta Dermato-Venereol

      Volume: 96 Pages: 557-559

    • DOI

      10.2340/00015555-2307

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15415, KAKENHI-PROJECT-15H04780, KAKENHI-PROJECT-15K15414, KAKENHI-PROJECT-16K15546, KAKENHI-PROJECT-15H04886
  • [Journal Article] Genetic analysis of a novel splice-site mutation in TMC8 reveals the in-vivo importance of the TMC domain of TMC82016

    • Author(s)
      Miyauchi T, Nomura T, Suzuki S, Takeda M, Shinkuma S, Arita K, Fujita Y, Shimizu H.
    • Journal Title

      Br J Dermatol

      Volume: in press

    • DOI

      10.1111/bjd.14569

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K09738, KAKENHI-PROJECT-15H04780, KAKENHI-PROJECT-25461681
  • [Journal Article] Extensive erythema and hyperkeratosis on the extremities and lumbar area as an unusual manifestation of Nagashima-type palmoplantar keratosis2016

    • Author(s)
      Miyauchi T, Nomura T, Suzuki S, Ohguchi Y, Yamaguchi Y, Shinkuma S, Natsuga K, Fujita Y, Shimizu H.
    • Journal Title

      Acta Derm Venereol

      Volume: in press Pages: 856-858

    • DOI

      10.2340/00015555-2391

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09738, KAKENHI-PROJECT-15H04780, KAKENHI-PROJECT-15K19668
  • [Journal Article] Revertant mosaicism in ichthyosis with confetti caused by a frameshift mutation in KRT1.2016

    • Author(s)
      Suzuki S, Nomura T, Miyauchi T, Takeda M, Nakamura H, Shinkuma S, Fujita Y, Akiyama M, Shimizu H
    • Journal Title

      Journal of Investigative Dermatology

      Volume: 136 Pages: 2093-2095

    • DOI

      10.1016/j.jid.2016.05.109

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09738
  • [Journal Article] Epitope-dependent pathogenicity of antibodies targeting a major bullous pemphigoid autoantigen collagen XVII/BP1802016

    • Author(s)
      Wada M, Nishie W, Ujiie H, Izumi K, Iwata H, Natsuga K, Nakamura H, Kitagawa Y, Shimizu H
    • Journal Title

      J Invest Dermatol

      Volume: in press Pages: 938-946

    • DOI

      10.1016/j.jid.2015.11.030

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461661, KAKENHI-PROJECT-15K19668
  • [Journal Article] Pruritic papules following lumbar corset use: a quiz2015

    • Author(s)
      Miyauchi T, Fujita Y, Takashima S, Morita Y, Suzuki S, Mizuno O, Saito N, Nomura T, Shimizu H
    • Journal Title

      Acta Derm Venereol

      Volume: 95 Pages: 762-765

    • DOI

      10.2340/00015555-2071

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H04780
  • [Journal Article] Plasma cell cheilitis extending beyond vermillion border2015

    • Author(s)
      Fujimura Y, Natsuga K*, Abe R, Morita Y, Nomura T, Shimizu H
    • Journal Title

      J Dermatol

      Volume: 42 Pages: 935-6

    • DOI

      10.1111/1346-8138.12985

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K19668, KAKENHI-PROJECT-15H04780
  • [Journal Article] Context-Dependent Regulation of Collagen XVII Ectodomain Sheddingin Skin.2015

    • Author(s)
      Nishie W, Natsuga K, Iwata H, Izumi K, Ujiie H, Toyonaga E, Hata H, NakamuraH, Shimizu H
    • Journal Title

      Am J Pathol

      Volume: 185(5) Pages: 1361-71

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461661
  • [Journal Article] Low-dose etretinate shows promise in management of punctate palmoplantar keratoderma type1: case report and review of the literature2015

    • Author(s)
      Nomura T, Moriuchi R, Takeda M, Suzuki S, Kikuchi K, Ito T, Shimizu H, Shimizu S
    • Journal Title

      J Dermatol

      Volume: 42 Pages: 889-892

    • DOI

      10.1111/1346-8138.12916

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H04780
  • [Journal Article] Skipped exon in COL7A1 determines the clinical phenotypes of dystrophic epidermolysis bullosa2015

    • Author(s)
      Toyonaga E, Nishie W, Komine M, Murata S, Shinkuma S, Natsuga K, Nakamura H, Ohtsuki M, Shimizu H.
    • Journal Title

      Br J Dermatol

      Volume: 172 Pages: 1141-1144

    • DOI

      10.1111/bjd.13386

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24249062, KAKENHI-PROJECT-15K19668, KAKENHI-PROJECT-25461661
  • [Journal Article] Context-dependent regulation of collagen XVII ectodomain shedding in skin2015

    • Author(s)
      Nishie W, Natsuga K, Iwata H, Izumi K, Ujiie H, Toyonaga E, Hata H, Nakamura H, Shimizu H.
    • Journal Title

      American Journal of Pathology

      Volume: in press Pages: 1361-1371

    • DOI

      10.1016/j.ajpath.2015.01.012

    • NAID

      120005752843

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24390274, KAKENHI-PROJECT-25461661, KAKENHI-PROJECT-26670516, KAKENHI-PROJECT-15K19668
  • [Journal Article] Identification of previously unknown SERPINB7 splice variants in patients with Nagashima-type palmoplantar keratosis reveals the importance of the CD-loop of SERPINB72015

    • Author(s)
      Suzuki S, Nomura T, Mizuno O, Fujita Y, Shimizu H
    • Journal Title

      Br J Dermatol

      Volume: 173 Pages: 1288-1290

    • DOI

      10.1111/bjd.13890

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H04780
  • [Journal Article] Safety of ustekinumab for the treatment of psoriasis vulgaris with myotonic dystrophy2015

    • Author(s)
      Fujita Y, Shinkuma S, Nomura T, Shimizu H
    • Journal Title

      Eur J Dermatol

      Volume: 26(2) Pages: 187-188

    • DOI

      10.1684/ejd.2015.2688

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H04780
  • [Journal Article] A case of non-solar-induced elastotic bands on the forearm2015

    • Author(s)
      Haga N, Abe R, Morita Y, Fujimura Y, Natsuga K, Nomura T, Kumakiri M, Shimizu H
    • Journal Title

      Eur J Dermatol

      Volume: 25 Pages: 508-509

    • DOI

      10.1684/ejd.2015.2629

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K19668, KAKENHI-PROJECT-15H04780
  • [Journal Article] Loss-of-function mutations in the gene encoding filaggrin underlie a Japanese family with food-dependent exercise-induced anaphylaxis.2015

    • Author(s)
      Mizuno O, Nomura T, Ohguchi Y, Suzuki S, Nomura Y, Hamade Y, Hoshina D, Sandilands A, Akiyama M, McLean WH, Abe R, Shimizu H.
    • Journal Title

      Journal of European Academy of Dermatology and Venereology

      Volume: 29(4) Pages: 805-808

    • DOI

      10.1111/jdv.12441

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24390152, KAKENHI-PROJECT-25670494, KAKENHI-PROJECT-25860925, KAKENHI-PROJECT-15H04780
  • [Journal Article] Deep venous thrombosis in patients with Behcet's disease.2015

    • Author(s)
      Horie K, Izumi K, Nishie W, Nomura T, Nomura Y, Arita K, Shimizu H.
    • Journal Title

      Journal of Dermatology

      Volume: 42 Pages: 101-102

    • DOI

      10.1111/1346-8138.12741

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25461681
  • [Journal Article] Striate palmoplantar keratoderma: Report of a novel DSG1 mutation and atypical clinical manifestations2015

    • Author(s)
      Nomura T, Mizuno O, Miyauchi T, Suzuki S, Shinkuma S, Hata H, Fujita Y, Akiyama M, Shimizu H.
    • Journal Title

      J Dermatol Sci

      Volume: 80 Pages: 223-225

    • DOI

      10.1016/j.jdermsci.2015.10.004

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K09738, KAKENHI-PROJECT-15H04780
  • [Journal Article] Punctate palmoplantar keratoderma type 1: a novel AAGAB mutation and efficacy of etretinate.2015

    • Author(s)
      Nomura T, Yoneta A, Pohler E, Suzuki S, Osawa R, Mizuno O, Ohguchi Y, Nomura Y, Yamashita T, McLean WHI, Shimizu H
    • Journal Title

      Acta Derm Venereol.

      Volume: in press Pages: 110-111

    • DOI

      10.2340/00015555-1832

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24390152, KAKENHI-PROJECT-24791130, KAKENHI-PROJECT-25670494, KAKENHI-PROJECT-25860925, KAKENHI-PROJECT-25461705
  • [Journal Article] Dermoscopic observation in adenoma of the nipple2015

    • Author(s)
      Takashima S, Fujita Y, Miyauchi T, Nomura T, Nishie W, Hamaoka H, Shimizu H.
    • Journal Title

      The Journal of Dermatology

      Volume: 42(3) Pages: 341-342

    • DOI

      10.1111/1346-8138.12780

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24390152
  • [Journal Article] Characteristic findings of handprint and dermoscopy in reticulate acropigmentation of Kitamura2014

    • Author(s)
      Koguchi H, Ujiie H, Aoyagi S, Osawa R, Shimizu H
    • Journal Title

      Clin Exp Dermatol

      Volume: 39 Pages: 85-87

    • DOI

      10.1111/ced.12191

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24791130, KAKENHI-PROJECT-25670494
  • [Journal Article] Tubular Spitz Naevus Mimicking Eccrine Spiradenoma2014

    • Author(s)
      Fujita Y, Aoyagi S, Tsujiwaki M, Homma E, Ujiie H, Fujita H, Hatanaka KC, Shimizu H
    • Journal Title

      Acta Derm Venereol

      Volume: 94 Pages: 114-115

    • DOI

      10.2340/00015555-1641

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670494
  • [Journal Article] Bilateral axillary Paget's disease: diagnostic pitfalls of dermoscopic features2014

    • Author(s)
      Hirata Y, Aoyagi S, Mizuno O, Homma E, Hata H, Shimizu H
    • Journal Title

      Int J Dermatol

      Volume: 53

    • DOI

      10.1111/j.1365-4632.2012.05605.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670494
  • [Journal Article] Highly prevalent SERPINB7 founder mutation causes pseudodominant inheritance pattern in Nagashima-type palmoplantar keratosis.2014

    • Author(s)
      Mizuno O, Nomura T, Suzuki S, Takeda M, Ohguchi Y, Fujita Y, Nishie W, Sugiura K, Akiyama M, Shimizu H
    • Journal Title

      British Journal of Dermatology

      Volume: 171 Pages: 847-853

    • DOI

      10.1111/bjd.13076

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23591617, KAKENHI-PROJECT-24390152, KAKENHI-PROJECT-25670494, KAKENHI-PROJECT-25860925, KAKENHI-PROJECT-26670526
  • [Journal Article] A new filaggrin gene mutation in a Korean patient with ichthyosis vulgaris2014

    • Author(s)
      Ohguchi Y, Nomura T, Suzuki S, Mizuno O, Nomura Y, Nemoto-Hasebe I, Okamoto H, Sandilands A, Akiyama M, McLean WH, Shimizu H
    • Journal Title

      Eur J Dermatol

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390152
  • [Journal Article] Sweet’s syndrome presenting with vegetative nodules on the hands: relationship to neutrophilic dermatosis of the dorsal hands2014

    • Author(s)
      Mizuno O, Yanagi T, Baba K, Yamane N, Inokuma D, Ito K, Akiyama M, Shimizu H
    • Journal Title

      Int J Dermatol

      Volume: (in press)

    • DOI

      10.1111/j.1365-4632.2011.05352.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591215, KAKENHI-PROJECT-24659526, KAKENHI-PROJECT-25670494
  • [Journal Article] Tubular apocrine adenoma clinically and dermoscopically mimicking basal cell carcinoma2014

    • Author(s)
      Ito T, Nomura T, Fujita Y, Abe R, Shimizu H
    • Journal Title

      J Am Acad Dermatol

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390152
  • [Journal Article] Long-term follow-up of cultured epidermal autograft in a patient with recessive dystrophic epidermolysis bullosa.2014

    • Author(s)
      Shinkuma S, Sawamura D, Fujita Y, Kawasaki H, Nakamura H, Inoie M, Nishie W, Shimizu H
    • Journal Title

      Acta Dermato-Venereologica

      Volume: 94(1) Pages: 98-99

    • DOI

      10.2340/00015555-1592

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390279, KAKENHI-PROJECT-24249062, KAKENHI-PROJECT-24650447, KAKENHI-PROJECT-25670494, KAKENHI-PROJECT-25713041
  • [Journal Article] Comprehensive screening for a complete set of Japanese-population-specific filaggrin gene mutations2014

    • Author(s)
      Kono M, Nomura T, Ohguchi Y, Mizuno O, Suzuki S, Tsujiuchi H, Hamajima M, McLean WHI, Shimizu H, Akiyama M
    • Journal Title

      Allergy

      Volume: 69 Pages: 537-540

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390152
  • [Journal Article] Recurrent course and CD30 expression of atypical T lymphocytes distinguish lymphomatoid papulosis type D from primary cutaneous aggressive epidermotropic CD8+ cytotoxic T-cell lymphoma2014

    • Author(s)
      Tsujiwaki M, Abe R, Ohguchi Y, Hoshina D, Murata J, Fujita Y, Nomura T, Ambo M, Shimizu H
    • Journal Title

      Acta Derm Venereol

      Volume: (in press) Pages: 613-614

    • DOI

      10.2340/00015555-1806

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670494, KAKENHI-PROJECT-25860924
  • [Journal Article] Intraoperative use of spectroscopic detection of protoporphyrin IX from oral 5-aminolevulinic acid on basal cell carcinoma and squamous cell carcinoma during Mohs surgery2014

    • Author(s)
      Aoyagi S, Hata H, Homma E, Horie K, Shimizu H
    • Journal Title

      Lasers Surg Med

      Volume: 46 Pages: 132-139

    • DOI

      10.1002/lsm.22208

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670494
  • [Journal Article] A new filaggrin gene mutation in a Korean patient with ichthyosis vulgaris2014

    • Author(s)
      Ohguchi Y, Nomura T, Suzuki S, Mizuno O, Nomura Y, Nemoto-Hasebe I, Okamoto H, Sandilands A, Akiyama M, Mclean WH, Shimizu H.
    • Journal Title

      European Journal of Dermatology

      Volume: 24(4) Pages: 491-493

    • DOI

      10.1684/ejd.2014.2410

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24390152
  • [Journal Article] Kindler Syndrome with Severe Intestinal Involvement: A 31-year Follow-up2014

    • Author(s)
      Shimizu S, Nishie W, Tsuchiya K, Inokuma D, Koguchi-Yoshioka H, Kikuchi K, Motoya S, Nakamura H, Shimizu H
    • Journal Title

      Acta Derm Venereol

      Volume: 94 Pages: 351-352

    • DOI

      10.2340/00015555-1696

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670494
  • [Journal Article] Localized cutaneous amyloidosis associated with poikilodermatous mycosis fungoides2014

    • Author(s)
      Izumi K, Arita K, Horie K, Hoshina D, Shimizu H
    • Journal Title

      Acta Dermato-Venereologica

      Volume: 94 Pages: 225-226

    • DOI

      10.2340/00015555-1657

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670494
  • [Journal Article] Ultrasound B-mode and Elastographic Findings of Angiomatoid Fibrous Histiocytoma2014

    • Author(s)
      Hata H, Natsuga K, Homma E, Aoyagi S, Shimizu H
    • Journal Title

      Clin Exp Dermatol

      Volume: 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670494
  • [Journal Article] A novel NCSTN mutation alone may be insufficient for the development of familial hidradenitis suppurativa2014

    • Author(s)
      Nomura Y, Nomura T, Suzuki S, Takeda M, Mizuno O, Ohguchi Y, Abe R, Murata Y, Shimizu H
    • Journal Title

      J Dermatol Sci

      Volume: 74 Pages: 180-182

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390152
  • [Journal Article] Distinct behavior of human Langerhans cells and inflammatory dendritic epidermal cells at tight junctions in patients with atopic dermatitis.2014

    • Author(s)
      Yoshida K, Kubo A, Fujita H, Yokouchi M, Ishii K, Kawasaki H, Nomura T, Shimizu H, Kouyama K, Ebihara T, Nagao K, Amagai M.
    • Journal Title

      Journal of Allergy and Clinical Immunology

      Volume: 134(4) Pages: 856-864

    • DOI

      10.1016/j.jaci.2014.08.001

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24390152, KAKENHI-PROJECT-25670507, KAKENHI-PROJECT-26293259, KAKENHI-PROJECT-26893260
  • [Journal Article] Tubular apocrine adenoma clinically and dermoscopically mimicking basal cell carcinoma2014

    • Author(s)
      Ito T, Nomura T, Fujita Y, Abe R, Shimizu H
    • Journal Title

      J Am Acad Dermatol

      Volume: 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670494
  • [Journal Article] Nanoparticle albumin-bound paclitaxel can be useful agent to advanced primary mucinous carcinoma of the skin2014

    • Author(s)
      Homma E, Hata H, Aoyagi S, Shimizu H
    • Journal Title

      Dermatologic therapy

      Volume: 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670494
  • [Journal Article] A novel NCSTN mutation alone may be insufficient for the development of familial hidradenitis suppurativa.2014

    • Author(s)
      Nomura Y, Nomura T, Suzuki S, Takeda M, Mizuno O, Ohguchi Y, Abe R, Murata Y, Shimizu H
    • Journal Title

      Journal of Dermatological Science

      Volume: 74 Pages: 180-182

    • DOI

      10.1016/j.jdermsci.2014.01.013

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25670494, KAKENHI-PROJECT-25860925
  • [Journal Article] An annexin A1-FPR1 interaction contributes to necroptosis of keratinocytes in severe cutaneous adverse drug reactions2014

    • Author(s)
      Saito N, Qiao H, Yanagi T, Shinkuma S, Nishimura K, Suto A, Fujita Y, Suzuki S, Nomura T, Nakamura H, Nagao K, Obuse C, Shimizu H, Abe R.
    • Journal Title

      Sci Transl Med.

      Volume: 6 Pages: 245-295

    • DOI

      10.1126/scitranslmed.3008227

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24249062, KAKENHI-PROJECT-24370071, KAKENHI-PROJECT-24390152, KAKENHI-PROJECT-24390275, KAKENHI-PUBLICLY-25132701, KAKENHI-PROJECT-25713041, KAKENHI-PROJECT-25870014, KAKENHI-PROJECT-26650002, KAKENHI-PLANNED-25116004
  • [Journal Article] Repeated skin sampling and prolonged incubation period identified cutaneous Mycobacterium chelonae infection on the face in an immunocompetent man2014

    • Author(s)
      Muramatsu K, Nomura T, Ito T, Hamade Y, Hirata Y, Fujita Y, Abe R, Shimizu H
    • Journal Title

      Br J Dermatol

      Volume: 170 Pages: 471-473

    • DOI

      10.1111/bjd.12638

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670494
  • [Journal Article] Nanoparticle albumin-bound paclitaxel can be useful agent to advanced primary mucinous carcinoma of the skin2014

    • Author(s)
      Ohguchi Y, Nomura T, Suzuki S, Mizuno O, Nomura Y, Nomoto-Hasebe I, Okamoto H, Sandilands A, Akiyama M, McLean WH, Shimizu H
    • Journal Title

      Dermatologic therapy

      Volume: 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670494
  • [Journal Article] Bullous Pemphigoid Autoantibodies Directly Induce Blister Formation without Complement Activation.2014

    • Author(s)
      Ujiie H, Sasaoka T, Izumi K, Nishie W, Shinkuma S, Natsuga K, Nakamura H, Shibaki A, Shimizu H
    • Journal Title

      The Journal of Immunology

      Volume: 193 Pages: 4415-4428

    • DOI

      10.4049/jimmunol.1400095

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25461661
  • [Journal Article] Comprehensive screening for a complete set of Japanese-population-specific filaggrin gene mutations.2014

    • Author(s)
      Kono M, Nomura T, Ohguchi Y, Mizuno O, Suzuki S, Tsujiuchi H, Hamajima N, McLean WH, Shimizu H, Akiyama M.
    • Journal Title

      Allergy.

      Volume: 69(4) Pages: 537-40

    • DOI

      10.1111/all.12369

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24390152, KAKENHI-PROJECT-24591646, KAKENHI-PROJECT-25670494
  • [Journal Article] Inherited epidermolysis bullosa: Updated recommendations on diagnosis and classification2014

    • Author(s)
      Fine JD, Bruckner-Tuderman L, Eady RA, Bauer EA, Bauer JW, Has C, Heagerty A, Hintner H, Hovnanian A, Jonkman MF, Leigh I, Marinkovich MP, Martinez AE, McGrath JA, Mellerio JE, Moss C, Murrell DF, Shimizu H, Uitto J, Woodley D, Zambruno G
    • Journal Title

      J Am Acad Dermatol

      Volume: (in press)

    • DOI

      10.1016/j.jaad.2014.01.903

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670494
  • [Journal Article] Technique for histological control of surgical margins in lip cancer2014

    • Author(s)
      Aoyagi S, Hata H, Homma E, Shimizu H
    • Journal Title

      J Dermatol

      Volume: 41 Pages: 316-318

    • DOI

      10.1111/1346-8138.12424

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670494
  • [Journal Article] A novel splice site mutation in NCSTN underlies a Japanese family with hidradenitis suppurativa2013

    • Author(s)
      Nomura Y
    • Journal Title

      The British Journal of Dermatology

      Volume: 168 Pages: 206-209

    • DOI

      10.1111/j.1365-2133.2012.11174.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23791245, KAKENHI-PROJECT-25670494
  • [Journal Article] Confluent and reticulated papillomatosis associated with 15q tetrasomy syndrome2013

    • Author(s)
      Koguchi H, Ujiie H, Aoyagi S, Osawa R, Shimizu H
    • Journal Title

      Acta Derm Venereol

      Volume: 93 Pages: 202-203

    • DOI

      10.2340/00015555-1437

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24791130, KAKENHI-PROJECT-25670494
  • [Journal Article] Indomethacin for Refractory Infantile Eosinophilic Pustular Folliculitis2013

    • Author(s)
      Toyonaga E, Abe R, Moriuchi R, Ito K, Abe Y, Shimizu H
    • Journal Title

      JAMA Dermatol

      Volume: 149 Pages: 367-368

    • DOI

      10.1001/2013.jamadermatol.591

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591215, KAKENHI-PROJECT-25670494
  • [Journal Article] A Novel Keratin 5 Mutation in an African Family with Epidermolysis Bullosa Simplex Indicates the Importance of the Amino Acid Located at the Boundary Site Between the H1 and Coil 1A Domains.2013

    • Author(s)
      Satoru Shinkuma、Wataru Nishie、 Witold K
    • Journal Title

      Acta Derm Venereol

      Volume: 印刷中 Pages: 585-587

    • DOI

      10.2340/00015555-1538

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23890006, KAKENHI-PROJECT-24249062, KAKENHI-PROJECT-24659516, KAKENHI-PROJECT-24659526, KAKENHI-PROJECT-25670494
  • [Journal Article] Pagetoid dyskeratosis with parallel ridge pattern under dermoscopy2013

    • Author(s)
      Toyonaga E, Inokuma D, Abe Y, Abe R, Shimizu H
    • Journal Title

      JAMA Dermatol

      Volume: 149 Pages: 109-111

    • DOI

      10.1001/archdermatol.2012.3201

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670494
  • [Journal Article] LC-MS/MS analysis of canine lipoproteins fractionated using the ultracentrifugation-precipitation method2013

    • Author(s)
      Suto A, Yamasaki M, Takasaki Y, Fujita Y, Abe R, Shimizu H, Ohta H, Takiguchi M
    • Journal Title

      J Vet Med Sci

      Volume: 75 Pages: 1471-1477

    • NAID

      130003362254

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670494
  • [Journal Article] Hallopeau-Siemens dystrophic epidermolysis bullosa due to homozygous 5818delC mutation in the COL7A gene2013

    • Author(s)
      Koshida S, Tsukamura A, Yanagi T, Nakahara S, Takeuchi Y, Kato T, Tanaka T, Nakano H, Shimizu H
    • Journal Title

      Pediatr Int

      Volume: 55 Pages: 234-237

    • DOI

      10.1111/j.1442-200x.2012.03638.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670494
  • [Journal Article] An Erythematous Plaque on the Breast : A Quiz2013

    • Author(s)
      Koguchi H, Arita K, Nakazato S, Moriuchi R, Yamane N, Shinkuma S, Matsumura K, Shimizu H
    • Journal Title

      Acta Derm Venereol

      Volume: (in press) Pages: 763-765

    • DOI

      10.2340/00015555-1527

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591215, KAKENHI-PROJECT-25670494
  • [Journal Article] A method for intravital monitoring of human cells using a far-red luminescent probe in graft-versus-host disease model mice2013

    • Author(s)
      Qiao H
    • Journal Title

      J Invest Dermatol

      Volume: 133 Pages: 841-84

    • DOI

      10.1038/jid.2012.345

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-10J06373, KAKENHI-PROJECT-25670494
  • [Journal Article] Dermoscopy of pseudoxanthoma elasticum-like papillary dermal elastolysis2013

    • Author(s)
      Ito T, Fujita Y, Nomura T, Abe R, Shimizu H
    • Journal Title

      J Am Acad Dermatol

      Volume: 69

    • DOI

      10.1016/j.jaad.2013.04.059

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390152, KAKENHI-PROJECT-25670494
  • [Journal Article] Linear congenital molluscum contagiosum on the coccygeal region2013

    • Author(s)
      Ujiie H, Aoyagi S, Hirata Y, Osawa R, Shimizu H
    • Journal Title

      Pediatr Dermatol

      Volume: 30

    • DOI

      10.1111/pde.12035

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24791130, KAKENHI-PROJECT-25670494
  • [Journal Article] Prevalent founder mutation c.736T>A of LIPH in autosomal recessive woolly hair of Japanese leads to variable severity of hypotrichosis in adulthood2013

    • Author(s)
      Tanahashi K, Sugiura K, Takeichi T, Takama H, Shinkuma S, Shimizu H, Akiyama M.
    • Journal Title

      J Eur Acad Dermatol Venereol

      Volume: 27 Pages: 1182-1184

    • DOI

      10.1111/j.1468-3083.2012.04526.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23249058, KAKENHI-PROJECT-23591617, KAKENHI-PROJECT-24659526, KAKENHI-PROJECT-25670494
  • [Journal Article] Stevens-Johnson syndrome/toxic epidermal necrolysis mouse model generated by using PBMCs and the skin of patients2013

    • Author(s)
      Saito N, Yoshioka N, Abe R, Qiao H, Fujita Y, Hoshina D, Suto A, Kase S, Kitaichi N, Ozaki M, Shimizu H.
    • Journal Title

      J Allergy Clin Immunol

      Volume: 131 Pages: 434-441

    • DOI

      10.1016/j.jaci.2012.09.014

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249062, KAKENHI-PROJECT-24390275, KAKENHI-PROJECT-25462731, KAKENHI-PROJECT-25670494
  • [Journal Article] Disturbed balance in three subpopulations of CD4(+)Foxp3(+) regulatory T cells in Stevens-Johnson syndrome and toxic epidermal necrolysis patients2013

    • Author(s)
      Yoshioka N, Suto A, Abe R, Saito N, Murata J, Hayashi-Ujiie I, Hoshina D, Fujita Y, Shimizu H.
    • Journal Title

      Clinical Immunology

      Volume: 148 Pages: 89-91

    • DOI

      10.1016/j.clim.2013.04.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390275, KAKENHI-PROJECT-25670494, KAKENHI-PROJECT-25713041, KAKENHI-PROJECT-25860924
  • [Journal Article] Cutaneous Manifestations of Helicobacter cinaedi Infection2013

    • Author(s)
      Shimizu S, Inokuma D, Watanabe M, Sakai T, Yamamoto S, Tsuchiya K, Shimizu H
    • Journal Title

      Acta Derm Venereol

      Volume: 93 Pages: 165-167

    • DOI

      10.2340/00015555-1396

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670494
  • [Journal Article] Minute reddish patch of extramammary Paget's disease with notable lymph node metastases2013

    • Author(s)
      Hata H, Aoyagi S, Baba K, Homma E, Shimizu H
    • Journal Title

      Int J Dermatol

      Volume: 52 Pages: 1593-1595

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670494
  • [Journal Article] Coexistence case of bullous pemphigoid and pemphigus foliaceus2013

    • Author(s)
      Tsujiwaki M, Abe R, Nomura Y, Nishimura M, Hoshina D, Shinkuma S, Natsuga K, Ujiie H, Arita K, Shimizu H
    • Journal Title

      Eur J Dermatol

      Volume: 23 Pages: 552-553

    • DOI

      10.1684/ejd.2013.2084

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670494
  • [Journal Article] Wells' Syndrome Associated with Chronic Myeloid Leukaemia2013

    • Author(s)
      Nakazato S, Fujita Y, Hamade Y, Nemoto-Hasebe I, Sugita J, Nishie W, Shimizu H
    • Journal Title

      Acta Derm Venereol

      Volume: 93巻 Pages: 375-376

    • DOI

      10.2340/00015555-1483

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24791129, KAKENHI-PROJECT-25670494
  • [Journal Article] Infantile eczema caused by formula milk.2013

    • Author(s)
      Ito T, Nishie W, Fujita Y, Abe R, Shimizu H
    • Journal Title

      Lancet

      Volume: 381 Pages: 1958-1958

    • DOI

      10.1016/s0140-6736(13)60684-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390152, KAKENHI-PROJECT-24390274, KAKENHI-PROJECT-25670494
  • [Journal Article] Establishment of a novel experimental model of human angiosarcoma and a VEGF-targeting therapeutic experiment2013

    • Author(s)
      Hoshina D, Abe R, Yoshioka N, Saito N, Hata H, Fujita Y, Aoyagi S, Shimizu H.
    • Journal Title

      J Dermatol Sci

      Volume: 70 Pages: 116-12

    • DOI

      10.1016/j.jdermsci.2013.02.008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249062, KAKENHI-PROJECT-25670494
  • [Journal Article] Long-term Follow-up of Cultured Epidermal Autograft in a Patient with Recessive Dystrophic Epidermolysis Bullosa2013

    • Author(s)
      Shinkuma S, Sawamura D, Fujita Y, Kawasaki H, Nakamura H, Inoie M, Nishie W, Shimizu H
    • Journal Title

      Acta Dermato-Venereologica

      Volume: In press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659516
  • [Journal Article] Impaired epidermal permeability barrier in mice lacking the Elovl1 gene responsible for very long-chain fatty acid production2013

    • Author(s)
      Sassa T, Ohno Y, Suzuki S, Nomura T, Nishioka C, Kashiwagi T, Hirayama T, Akiyama M, Taguchi R, Shimizu H, Itohara S, Kihara A.
    • Journal Title

      Mol Cell Biol.

      Volume: 33 Pages: 2787-2796

    • DOI

      10.1128/mcb.00192-13

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23249058, KAKENHI-PROJECT-23370057, KAKENHI-PROJECT-24390152, KAKENHI-PROJECT-24590073, KAKENHI-PROJECT-24619007, KAKENHI-PROJECT-24659526, KAKENHI-PROJECT-25670494
  • [Journal Article] Intractable erythematous plaques on the hands : palmoplantar eosinophilic pustular folliculitis2013

    • Author(s)
      Izumi K, Yanagi T, Akiyama M, Moriuchi R, Arita K, Shimizu H.
    • Journal Title

      Int J Dermatol

      Volume: 52 Pages: 1274-1275

    • DOI

      10.1111/j.1365-4632.2011.05139.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659526, KAKENHI-PROJECT-25670494
  • [Journal Article] Antibodies to pathogenic epitopes on type XVII collagen cause skin fragility in a complement-dependent and -independent manner2012

    • Author(s)
      Natsuga K, Nishie W, Shinkuma S, Ujiie H, Nishimura M, Sawamura D, Shimizu H
    • Journal Title

      Journal of Immunology

      Volume: (in press) Pages: 5792-5799

    • DOI

      10.4049/jimmunol.1003402

    • NAID

      10031131103

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20689021, KAKENHI-PROJECT-23591635, KAKENHI-PROJECT-23659538, KAKENHI-PROJECT-23791242, KAKENHI-PROJECT-24390152, KAKENHI-PROJECT-24659514
  • [Journal Article] CYP4F22 is highly expressed at the site and onset of keratinization during human skin development2012

    • Author(s)
      Sasaki K, Akiyama M, Yanagi T, Sakai K, Miyamura Y, Sato M, Shimizu H
    • Journal Title

      J Dermatol Sci

      Volume: 65 Pages: 156-158

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390304
  • [Journal Article] Noncollagenous 16A domain of type XVII collagen-reactive CD4+ T cells play a pivotal role in the development of active disease in experimental bullous pemphigoid model2012

    • Author(s)
      Ujiie H, Shibaki A, Nishie W, Shinkuma S, Moriuchi R, Qiao H, Shimizu H
    • Journal Title

      Clinical Immunology

      Volume: 142 Pages: 167-175

    • DOI

      10.1016/j.clim.2011.10.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20689021, KAKENHI-PROJECT-21249063, KAKENHI-PROJECT-23591635, KAKENHI-PROJECT-23659538, KAKENHI-PROJECT-23791242
  • [Journal Article] Antibodies to pathogenic epitopes on type XVII collagen cause skin fragility in a complement-dependent and-independent manner2012

    • Author(s)
      Natsuga K, Nishie W, Shinkuma S, Ujiie H, Nishimura M, Sawamura D, Shimizu H
    • Journal Title

      Journal of Immunology

      Volume: (印刷中)

    • NAID

      10031131103

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] The beta 9 loop domain of PA-PLA1 alpha has a crucial role in autosomal recessive woolly hair/hypotrichosis2012

    • Author(s)
      Shinkuma S, Inoue A, Aoki J, Nishie W, Natsuga K, Ujiie H, Nomura T, Abe R, Akiyama M, Shimizu H
    • Journal Title

      J Invest Dermatol.

      Volume: (印刷中) Pages: 2093-2095

    • DOI

      10.1038/jid.2012.96

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063, KAKENHI-PROJECT-21390015, KAKENHI-PLANNED-22116004, KAKENHI-PROJECT-22659013, KAKENHI-PROJECT-23659546, KAKENHI-PROJECT-23791245, KAKENHI-PROJECT-24390152, KAKENHI-PROJECT-24659025, KAKENHI-PROJECT-24659526, KAKENHI-ORGANIZER-22116001
  • [Journal Article] Antibodies to pathogenic epitopes on type XVII collagen cause skin fragility in a complement-dependent and independent manner2012

    • Author(s)
      Natsuga K, Nishie W, Shinkuma S, UjiieH, Nishimura M, Sawamura D, Shimizu H
    • Journal Title

      J Immunol

      Volume: 188 Pages: 5792-5799

    • NAID

      10031131103

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Possible modifier effects of keratin 17 gene mutation onkeratitis-ichthyosis-deafness syndrome2012

    • Author(s)
      Natsuga K, Shinkuma S, Kanda M, SuzukiY, Chosa N, Narita Y, Setoyama M, Nishie W, Akiyama M, Shimizu H
    • Journal Title

      Br J Dermatol

      Volume: 166 Pages: 903-905

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] A group of atopic dermatitis without IgE elevation or barrier impairment shows a high Th1 frequency: Possible immunological state of the intrinsic type.2012

    • Author(s)
      Kabashima-Kubo R, Nakamura M, Sakabe, J, Sigita K, Hino R, Mori T, Kobayashi M, Bito T, Kabashima K, Ogasawara K, Nomura Y, Nomura T, Akiyama M, Shimizu H, Tokura Y.
    • Journal Title

      Journal of Dermatological Science

      Volume: 67 Pages: 37-43

    • DOI

      10.1016/j.jdermsci.2012.04.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390370, KAKENHI-PROJECT-23591662, KAKENHI-PROJECT-23659546, KAKENHI-PROJECT-23791245, KAKENHI-PROJECT-24390152, KAKENHI-PROJECT-24659525, KAKENHI-PROJECT-24659526, KAKENHI-PROJECT-24890082
  • [Journal Article] Noncollagenous 16A domain of type XVII collagen-reactive CD4+ T cells play a pivotal role in the development of active disease in experimental bullous pemphigoid model2012

    • Author(s)
      Ujiie H, Shibaki A, Nishie W, ShinkumaS, Moriuchi R, Qiao H, Shimizu H
    • Journal Title

      Clin Immunol

      Volume: 142 Pages: 167-175

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Evidence for pathogenicity of autoreactive T cells in autoimmune bullous diseases shown by animal disease models2012

    • Author(s)
      Ujiie H, Shimizu H
    • Journal Title

      Experimental Dermatology

      Volume: 21 Pages: 901-5

    • DOI

      10.1111/exd.12011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591635, KAKENHI-PROJECT-23791242
  • [Journal Article] Type VII collagen deficiency causes defective tooth enamel formation due to poor differentiation of ameloblasts.2012

    • Author(s)
      Umemoto H, Akiyama M, Domon T, Nomura T, Shinkuma S, Ito K, Asaka T, Sawamura D, Uitto J, Uo M, Kitagawa Y, Shimizu H
    • Journal Title

      The American jounal of Pathology

      Volume: 181 Pages: 1659-1671

    • DOI

      10.1016/j.ajpath.2012.07.018

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591215, KAKENHI-PROJECT-23390279, KAKENHI-PROJECT-23659546, KAKENHI-PROJECT-23791245, KAKENHI-PROJECT-23890006, KAKENHI-PROJECT-24249062, KAKENHI-PROJECT-24659516, KAKENHI-PROJECT-24659526, KAKENHI-PROJECT-24890008
  • [Journal Article] A novel splice site mutation in NCSTN underlies a Japanese family with hidradenitis suppurativa.2012

    • Author(s)
      Nomura Y, Nomura T, Mizuno H, Shimizu H, et al
    • Journal Title

      Br J Dermatol

      Volume: 168 Pages: 206-209

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390152
  • [Journal Article] Haploinsufficiency for AAGAB causes clinically heterogeneous forms of punctate palmoplantar keratoderma.2012

    • Author(s)
      Pohler E
    • Journal Title

      Nature Genetics

      Volume: 44 Pages: 1272-1276

    • DOI

      10.1038/ng.2444

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659546, KAKENHI-PROJECT-23791245, KAKENHI-PROJECT-24390152, KAKENHI-PROJECT-24659526
  • [Journal Article] Subepidermal blistering disease with 3 distinct autoantibodies : Anti-BP230, anti-laminin gamma-1, and anti-laminin-3322011

    • Author(s)
      Kikuchi K, Natsuga K, Shinkuma S, Nishie W, Kajita S, Sato H, Shimizu H
    • Journal Title

      J Am Acad Dermatol

      Volume: 65 Pages: 878-880

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Extremely severe palmoplantar hyperkeratosis in a generalized epidermolytic hyperkeratosis patient with a keratin 1 gene mutation2011

    • Author(s)
      Osawa R, Akiyama M, Izumi K, Ujiie H, Sakai K, Nemoto-Hasebe I, Yanagi T, Koizumi H, Shimizu H
    • Journal Title

      J Am Acad Dermatol

      Volume: 64 Pages: 991-993

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Expression of exon-8-skipped kindlin-1does not compensate for defects of Kindler syndrome2011

    • Author(s)
      Natsuga K, Nishie W, Shinkuma S, Nakamura H, Matsushima Y, Tatsuta A, Komine M, Shimizu H
    • Journal Title

      J Dermatol Sci

      Volume: 61 Pages: 38-44

    • NAID

      10030889702

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Hair follicle stem cells provide a functional niche for melanocyte stem cells2011

    • Author(s)
      Tanimura S, Tadokoro Y, Inomata K, Binh NT, Nishie W, Yamazaki S, NakauchiH, Tanaka Y, McMillan JR, Sawamura D, Yancey K, Shimizu H, Nishimura EK
    • Journal Title

      Cell Stem Cell

      Volume: 8 Pages: 177-187

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Malignant skin tumours in patients with inherited ichthyosis2011

    • Author(s)
      Natsuga K, Akiyama M, Shimizu H
    • Journal Title

      Br J Dermatol

      Volume: 165 Pages: 263-268

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Type XVII collagen ELISA indices significantly decreased after Bullous pemphigoid remission2011

    • Author(s)
      Kusajima E, Akiyama M, Sato M, Natsuga K, Shimizu H
    • Journal Title

      Int J Dermatol

      Volume: 50 Pages: 238-240

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Abca12-mediated lipid transport and snap29-dependent trafficking of lamellar granules are critical for epidermal morphogenesis in Zebrafish Disease Model of Ichthyosis2011

    • Author(s)
      Li Q, Frank M, Akiyama M, Shimizu H, Ho S-Y, Thisse C, Thisse B, Sprecher E, Uitto J
    • Journal Title

      Dis Model Mech

      Volume: 4 Pages: 777-785

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390304
  • [Journal Article] Extremely severe palmoplantar hyperkeratosis in a generalized epidermolytic hyperkeratosis patient with a keratin 1 gene mutation2011

    • Author(s)
      Osawa R, Akiyama M, Izumi K, Ujiie H, Sakai K, Nemoto-Hasebe I, Yanagi T, Koizumi H, Shimizu H
    • Journal Title

      J Am Acad Dermatol

      Volume: 64 Pages: 991-993

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390304
  • [Journal Article] Rapid immunochromatographic test for serum granulysin is useful for the prediction of Stevens-Johnson syndrome and toxic epidermal necrolysis2011

    • Author(s)
      Fujita Y, Yoshioka N, Abe R, MurataJ, Hoshina D, Mae H, Shimizu H
    • Journal Title

      J AmAcad Dermatol

      Volume: 65 Pages: 65-68

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] New insight into genotype/phenotype correlations in ABCA12 mutations in harlequin ichthyosis2011

    • Author(s)
      Umemoto H, Akiyama M, Yanagi T, Sakai K, Aoyama Y, Oizumi A, Suga Y, Kitagawa Y, Shimizu H
    • Journal Title

      J Dermatol Sci

      Volume: 61 Pages: 136-138

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390304
  • [Journal Article] Hair follicle stem cells provide a functional niche for melanocyte stem cells.2011

    • Author(s)
      Tanimura S, Tadokoro Y, Inomata K, Tanaka Y, Nishie W, McMillan JR, Sawamura D, Yancey K, Shimizu H, Nishimura EK
    • Journal Title

      Cell Stem Cell 8

      Pages: 177-187

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390305
  • [Journal Article] Childhood subepidermal blistering disease with autoantibodies to type VII collagen and laminin-3322011

    • Author(s)
      Lin HY, Yanagi T, Akiyama M, IitaniMM, Moriuchi R, Natsuga K, Shinkuma S, Yamane N, Inokuma D, Arita K, Shimizu H
    • Journal Title

      Br J Dermatol

      Volume: 164 Pages: 452-454

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] New insight into genotype/phenotype correlations in ABCA12 mutations in harlequin ichthyosis2011

    • Author(s)
      Umemoto H, Akiyama M, Yanagi T, SakaiK, Aoyama Y, Oizumi A, Suga Y, KitagawaY, Shimizu H
    • Journal Title

      J Dermatol Sci

      Volume: 61 Pages: 136-138

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Human IgG1 monoclonal antibody against human collagen 17 noncollagenous 16A domain induces blisters via complement activation in experimental bullous pemphigoid model2011

    • Author(s)
      Li Q, Ujiie H, Shibaki A, Wang G, Moriuchi R, Qiao HJ, Morioka H, ShinkumaS, Natsuga K, Long HA, Nishie W, ShimizuH
    • Journal Title

      J Immunol

      Volume: 185 Pages: 7746-7755

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Definitions and outcome measures for bullous pemphigoid : Recommendations by an international panel of experts2011

    • Author(s)
      Murrell DF, Daniel BS, Joly P, Borradori L, Amagai M, Hashimoto T, Caux, Marinovic B, Sinha AA, Hertl M, Bernard P, Sirois D, Cianchini G, Fairley JA, Jonkman MF, Pandya AG, Rubenstein D, Zillikens D, Payne AS, Woodley D, Zambruno G, Aoki V, Pincelli C, Diaz L, Hall RP, Meurer M, Mascaro JM, Jr., Schmidt E, Shimizu H, Zone J, Swerlick R, Mimouni D, Culton D, Lipozencic J, Bince B, Bystryn JC, Werth VP
    • Journal Title

      J AmAcad Dermatol

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] AKT has an anti-apoptotic role in ABCA12-deficient keratinocytes2011

    • Author(s)
      Yanagi T, Akiyama M, Nishihara H, Miyamura Y, Sakai K, Tanaka S, Shimizu H
    • Journal Title

      J Invest Dermatol

      Volume: 131 Pages: 1942-1945

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390304
  • [Journal Article] A founder effect of c.1938delC in ITGB4 underlies junctional epidermolysis bullosa and its application for prenatal testing2011

    • Author(s)
      Natsuga K, Nishie W, Shinkuma S, Nakamura H, Arita K, Yoneda K, Kusaka T, Yanagihara T, Kosaki R, Sago H, Akiyama M, Shimizu H
    • Journal Title

      Exp Dermatol

      Volume: 20 Pages: 74-76

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] 表皮水疱症:病態と診断2011

    • Author(s)
      新熊悟, 清水宏
    • Journal Title

      日本皮膚科学会雑誌

      Volume: 121 Pages: 127-133

    • NAID

      10031164946

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659202
  • [Journal Article] Malignant skin tumours in patients with inherited ichthyosis2011

    • Author(s)
      Natsuga K, Akiyama M, Shimizu H
    • Journal Title

      Br J Dermatol

      Volume: 165 Pages: 263-268

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390304
  • [Journal Article] ABCA12 dysfunction causes a disorder in glucosylceramide accumulation during keratinocyte differentiation2010

    • Author(s)
      Mitsutake S, Suzuki C, Akiyama M, Tsuji K, Yanagi T, Shimizu H, Igarashi Y
    • Journal Title

      J Dermatol Sci

      Volume: 60 Pages: 128-129

    • NAID

      10027474089

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390304
  • [Journal Article] Bone marrow transplantation restores epidermal basement membrane protein expression and rescues epidermolysis bullosa model mice.2010

    • Author(s)
      Fujita Y, Abe R, Inokuma D, Sasaki M, Hoshina D, Natsuga K, Nishie W, McMillan JR, Nakamura H, Shimizu T, Akiyama M, Sawamura D, Shimizu H.
    • Journal Title

      Proc Natl Acad Sci USA 107

      Pages: 14345-50

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591332
  • [Journal Article] Revised nomenclature and classification of inherited ichthyoses : Results of the First Ichthyosis Consensus Conference in Soreze 20092010

    • Author(s)
      Oji V, Tadini G, Akiyama M, Blanchet-Bardon C, Bodemer C, Bourrat E, Coudiere P ; DiGiovanna JJ, Elias P, Fischer J, Fleckmann P, Gina M, Harper J, Hashimoto T, Hausser I, Hennies HC, Hohl D, Hovnanian A, Ishida-Yamamoto A, Jacyk WK, Leachman S, Leigh I, Mazereeuw-Hautier J, Milstone L, Morice-Picard F, Paller AS, Richard G, Schmuth M, Shimizu H, Sprecher E, vanSteensel M, Taieb A, Toro JR, Vabres P, Vahlquist A, Williams M, Traupe H
    • Journal Title

      J Am Acad Dermatol

      Volume: 63 Pages: 607-641

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390304
  • [Journal Article] Circulating IgA and IgE autoantibodies in antilaminin-332 mucous membrane pemphigoid2010

    • Author(s)
      Natsuga K, Nishie W, Shinkuma S, Moriuchi R, Shibata M, Nishimura M, Hashimoto T, Shimizu H
    • Journal Title

      Br J Dermatol 162

      Pages: 513-517

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Response of intractable skin ulcers in recessive dystrophic epidermolysis bullosa patients to an allogeneic cultured dermal substitute2010

    • Author(s)
      Natsuga K, Sawamura D, Goto M, Homma E, Goto-Ohguchi Y, Aoyagi S, Akiyama M, Kuroyanagi Y, Shimizu H
    • Journal Title

      Acta Derm Venereol 90

      Pages: 165-169

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Partially disturbed lamellar granule secretion in mild congenital ichthyosiform erythroderma with ALOX12B mutations2010

    • Author(s)
      Akiyama M, Sakai K, Yanagi T, Tabata N, Yamada M, Shimizu H
    • Journal Title

      Br J Dermatol

      Volume: 163 Pages: 201-204

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390304
  • [Journal Article] Neutral lipid storage leads to acylceramide deficiency, likely contributing to the pathogenesis ofDorfman-Chanarin syndrome2010

    • Author(s)
      Uchida Y, Cho Y, Moradian S, Kim J, Nakajima K, Crumrine D, Park K, Ujihara M, Akiyama M, Shimizu H, Holleran WM, Sano S, Elias PM
    • Journal Title

      J Invest Dermatol

      Volume: 130 Pages: 2497-2499

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390304
  • [Journal Article] Controlling the histological margin for non-melanoma skin cancer conveniently using a double-bladed scalpel2010

    • Author(s)
      Aoyagi S, Hata H, Homma E, Shimizu H
    • Journal Title

      J Surg Oncol 101

      Pages: 175-179

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Response of intractable skin ulcers in recessive dystrophic epidermolysis bullosa patients to an allogeneic cultured dermal substitute.2010

    • Author(s)
      Natsuga K, Sawamura D, Goto M, Homma E, Goto-Ohguchi Y, Aoyagi S, Akiyama M, Kuroyanagi Y, Shimizu H
    • Journal Title

      Acta Derm Venereol 90

      Pages: 165-169

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390305
  • [Journal Article] Epidermal triglyceride levels are correlated with severity of ichthyosis in Dorfman-Chanarin syndrome2010

    • Author(s)
      Ujihara M, Nakajima K, Yamamoto M, Teraishi M, Uchida Y, Akiyama M, Shimizu H, Sano S
    • Journal Title

      J Dermatol Sci 57

      Pages: 102-107

    • NAID

      10027399559

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Plectin expression patterns determine two distinct subtypes of epidermolysis bullosa simplex2010

    • Author(s)
      Natsuga K, Nishie W, Akiyama M, Nakamura H, Shinkuma S, McMillan JR, Nagasaki A, Has C, Ouchi T, Ishiko A, Hirako Y, Owaribe K, Sawamura D, Bruckner-Tuderman L, Shimizu H
    • Journal Title

      Hum Mutat 31

      Pages: 308-316

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Successful treatment of nail lichen planus with topical tacrolimus2010

    • Author(s)
      Ujiie H, Shibaki A, Akiyama M, Shimizu H
    • Journal Title

      Acta Derm Venereol 90

      Pages: 218-219

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Prevalent LIPH founder mutations lead to loss of P2Y5 activation ability of PA-PLA1alpha in autosomal recessive hypotrichosis.2010

    • Author(s)
      Shinkuma S, Akiyama M, Inoue A, Aoki J, Natsuga K, Nomura T, Arita K, Abe R, Ito K, Nakamura H, Ujiie H, Shibaki A, Suga H, Tsunemi Y, Nishie W, Shimizu H.
    • Journal Title

      Hum Mutat 31

      Pages: 602-10

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591332
  • [Journal Article] Self-improvement of keratinocyte differentiation defects during skin maturation in ABCA12 deficient harlequin ichthyosis model mice2010

    • Author(s)
      Yanagi T, Akiyama M, Nishihara H, Ishikawa J, Sakai K, Miyamura Y, Naoe A, Kitahara T, Tanaka S, Shimizu H
    • Journal Title

      Am J Pathol

      Volume: 177 Pages: 106-118

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390304
  • [Journal Article] A novel active mouse model for bullous pemphigoid targeting humanized pathogenic antigen2010

    • Author(s)
      Ujiie H, Shibaki A, Nishie W, Sawamura D, Wang G, Tateishi Y, Li Q, Moriuchi R, Qiao H, Nakamura H, Akiyama M, Shimizu H
    • Journal Title

      J Immunol 184

      Pages: 2166-2174

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] A novel active mouse model for bullous pemphigoid targeting humanized pathogenic antigen2010

    • Author(s)
      Ujiie H, Shibaki A, Nishie W, Sawamura D, Wang G, Tateishi Y, Li Q, Moriuchi R, Qiao H, Nakamura H, Akiyama M, Shimizu H
    • Journal Title

      J Immunol 184

      Pages: 2166-2174

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390305
  • [Journal Article] Plectin expression patterns determine two distinct subtypes of epidermolysis bullosa simplex.2010

    • Author(s)
      Natsuga K, Nishie W, Akiyama M, Nakamura H, Shinkuma S, McMillan JR, Nagasaki A, Has C, Ouchi T, Ishiko A, Hirako Y, Owaribe K, Sawamura D, Bruckner-Tuderman L, Shimizu H
    • Journal Title

      Hum Mutat 31

      Pages: 308-316

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390305
  • [Journal Article] Blockade of autoantibody-initiated tissue damage by using recombinant fab antibody fragments against pathogenic autoantigen.2010

    • Author(s)
      Wang G, Ujiie H, Shibaki A, Nishie W, Tateishi Y, Kikuchi K, Li Q, McMillan JR, Morioka H, Sawamura D, Nakamura H, Shimizu H
    • Journal Title

      Am J Pathol 176

      Pages: 914-925

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390305
  • [Journal Article] A novel active mouse model for Bullous pemphigoid targeting humanized pathogenic antigen2010

    • Author(s)
      Ujiie H, Shibaki A, Nishie W, Sawamura D, Wang G, Tateishi Y, Li Q, Moriuchi R, Qiao H, Nakamura H, AkiyamaM, Shimizu H
    • Journal Title

      J Immunol

      Volume: 184 Pages: 2166-6174

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Blockade of autoantibody-initiated tissue damage by using recombinant fab antibody fragments against pathogenic autoantigen2010

    • Author(s)
      Wang G, Ujiie H, Shibaki A, Nishie W, Tateishi Y, Kikuchi K, Li Q, McMillan JR, Morioka H, Sawamura D, Nakamura H, Shimizu H
    • Journal Title

      Am J Pathol 176

      Pages: 914-925

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] An Indian family with Sjogren-Larsson syndrome caused by a novel ALDH3A2 mutation2010

    • Author(s)
      Sakai K, Akiyama M, Yanagi T, Nampoothiri S, Mampilly T, V S, Shimizu H
    • Journal Title

      Int J Dermatol

      Volume: 49 Pages: 1031-1033

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390304
  • [Journal Article] Bone marrow transplantation restores epidermal basement membrane protein expression and rescues epidermolysis bullosa model mice2010

    • Author(s)
      Fujita Y, Abe R, Inokuma D, Sasaki M, Hoshina D, Natsuga K, Nishie W, McMillan JR, Nakamura H, Shimizu T, Akiyama M, Sawamura D, Shimizu H
    • Journal Title

      Proc Natl Acad Sci USA. 107

      Pages: 14345-14350

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390305
  • [Journal Article] Hereditary benign telangiectasia : two families with punctate telangiectasias surrounded by anemic halos2010

    • Author(s)
      Ujiie H, Kodama K, Akiyama M, Shimizu H
    • Journal Title

      Arch Dermatol 146

      Pages: 98-99

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Transglutaminase1 preferred substrate peptide K5 is an efficient tool in diagnosis of lamellar ichthyosis2010

    • Author(s)
      Akiyama M, Sakai K, Yanagi T, Fukushima S, Ihn H, Hitomi K, Shimizu H
    • Journal Title

      Am J Pathol

      Volume: 176 Pages: 1592-1599

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390304
  • [Journal Article] DNA vaccination against macrophage migration inhibitory factor improves atopic dermatitis in murine models2009

    • Author(s)
      Hamasaka A, Abe R, Koyama Y, Yoshioka N, Fujita Y, Hoshina D, Sasaki M, Hirasawa T, Onodera S, Ohshima S, Leng L, Bucala R, Nishihira J, Shimizu T, Shimizu H
    • Journal Title

      J Allergy Clin Immunol 124

      Pages: 90-99

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Animal models of epidermolysis bullosa2009

    • Author(s)
      Natsuga K, Shinkuma S, Nishie W, Shimizu H
    • Journal Title

      Dermatol Clin 28

      Pages: 137-142

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Bloody nipple discharge in an infant2009

    • Author(s)
      Ujiie H, Akiyama M, Osawa R, Shida S, Aoyagi S, Shimizu H
    • Journal Title

      Arch Dermatol 145

      Pages: 1068-1069

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] A novel PTPN11 missense mutation in a patient with LEOPARD syndrome2009

    • Author(s)
      Osawa R, Akiyama M, Yamanaka Y, Ujiie H, Nemoto-Hasebe I, Takeda A, Yanagi T, Shimizu H
    • Journal Title

      Br J Dermatol 161

      Pages: 1202-1204

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Usefulness of real-time tissue elastography for detecting lymph-node metastases in squamous cell carcinoma2009

    • Author(s)
      Aoyagi S, Izumi K, Hata H, Kawasaki H, Shimizu H
    • Journal Title

      Clin Exp Dermatol 34

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Current advances in gene therapy for the treatment of genodermatoses2009

    • Author(s)
      Long HA, McMillan JR, Qiao H, Akiyama M, Shimizu H
    • Journal Title

      Curr Gene Ther 9

      Pages: 487-494

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Type XVII collagen is a key player in tooth enamel formation2009

    • Author(s)
      Asaka T, Akiyama M, Domon T, Nishie W, Natsuga K, Fujita Y, Abe R, Kitagawa Y, Shimizu H
    • Journal Title

      Am J Pathol 174

      Pages: 91-100

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Epidermolysis bullosa(EB)-diagnosis and therapy2009

    • Author(s)
      McMillan JR, Long HA, Akiyama M, Shimizu H, Kimble RM
    • Journal Title

      Wound Practice and Research 17

      Pages: 62-70

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Granulysin as a marker for early diagnosis of the Stevens-Johnson syndrome2009

    • Author(s)
      Abe R, Yoshioka N, Murata J, Fujita Y, Shimizu H
    • Journal Title

      Ann Intern Med 151

      Pages: 514-515

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] A novel humanized neonatal autoimmune blistering skin disease model induced by maternally transferred antibodies.2009

    • Author(s)
      Nishie W, Sawamura D, Natsuga K, Shinkuma S, Goto M, Shibaki A, Ujiie H, Olasz E, Yancey KB, Shimizu H
    • Journal Title

      J Immunol 183

      Pages: 4088-4093

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390305
  • [Journal Article] Deficient deletion of apoptotic cells by macrophage migration inhibitory factor(MIF)overexpression accelerates photocarcinogenesis2009

    • Author(s)
      Honda A, Abe R, Yoshihisa Y, Makino T, Matsunaga K, Nishihira J, Shimizu H, Shimizu T
    • Journal Title

      Carcinogenesis 30

      Pages: 1597-1605

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] ABCA12 is a major causative gene for non-bullous congenital ichthyosiform erythroderma2009

    • Author(s)
      Sakai K, Akiyama M, Yanagi T, McMillanJR, Suzuki T, Tsukamoto K, Sugiyama H, Hatano Y, Hayashitani M, Takamori K, Nakashima Keiko, Shimizu H
    • Journal Title

      J Invest Dermatol

      Volume: 129

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390304
  • [Journal Article] Widespread keratosis follicularis squamosa2009

    • Author(s)
      Nomura Y, Abe M, Natsuga K, Moriuchi R, Kawasaki H, Mayuzumi M, Yasuoka A, Shimizu H
    • Journal Title

      Clin Exp Dermatol 34

      Pages: 519-520

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Birt-Hogg-Dube syndrome with clear-cell and oncocytic renal tumour and trichoblastoma associated with a novel FLCN mutation2009

    • Author(s)
      Imada K, Dainichi T, Yokomizo A, Tsunoda T, Song YH, Nagasaki A, Sawamura D, Nishie W, Shimizu H, Fukagawa S, Urabe K, Furue M, Hashimoto T, Naito S
    • Journal Title

      Br J Dermatol 160

      Pages: 1350-1353

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] A severe and refractory case of anti-p200 pemphigoid resulting in multiple skin ulcers and scar formation.2009

    • Author(s)
      Goto-Ohguchi Y, Nishie W, Akiyama M, Tateishi Y, Aoyagi S, Tsuji-Abe Y, Sawamura D, Ishii N, Hashimoto T, Shimizu H
    • Journal Title

      Dermatology 218

      Pages: 265-271

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390305
  • [Journal Article] Glycosylation specific for adhesion molecules in epidermis and its receptor revealed by glycoform-focused reverse genomics2009

    • Author(s)
      Uematsu R, Shinohara Y, Nakagawa H, Kurogochi M, Furukawa J, Miura Y, Akiyama M, Shimizu H, Nishimura S
    • Journal Title

      Mol Cell Proteomics 8

      Pages: 232-244

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Melanonychia caused by Stenotrophomonas maltophilia2009

    • Author(s)
      Hamasaka E, Akiyama M, Hala H, Aoyagi S, Shimizu H
    • Journal Title

      Clin Exp Dermatol 34

      Pages: 242-243

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Clinical severity correlates with impaired barrier in filaggrin-related eczema2009

    • Author(s)
      Nemoto-Hasebe I, Akiyama M, Nomura T, Sandilands A, McLean WH, Shimizu H
    • Journal Title

      J Invest Dermatol 129

      Pages: 682-689

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Prevalent and rare mutations in the gene encoding filaggrin in Japanese patients with ichthyosis vulgaris and atopic dermatitis2009

    • Author(s)
      Nomura T, Akiyama M, Sandilands A, Nemoto-Hasebe I, Sakai K, Nagasaki A, Palmer CN, Smith FJ, McLean WH, Shimizu H
    • Journal Title

      J Invest Dermatol 129

      Pages: 1302-1305

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Pemphigus foliaceus associated with oesophageal cancer2009

    • Author(s)
      Shinkuma S, Akiyama M, Torii-Saito N, Natsuga K, Tateishi Y, Ito K, Hirota J, Shimizu Y, Shichinohe T, Shimizu H
    • Journal Title

      J Eur Acad Dermatol Venereol 23

      Pages: 473-474

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Bone marrow-derived cells are not the origin of the cancer stem cells in ultraviolet-induced skin cancer2009

    • Author(s)
      Ando S, Abe R, Sasaki M, Murata J, Inokuma D, Shimizu H
    • Journal Title

      Am J Pathol 174

      Pages: 595-601

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Morphological and genetic analysis of steatocystoma multiplex in an Asian family with pachyonychia congenita type 2 harbouring a KRT17 missense mutation2009

    • Author(s)
      Kanda M, Natsuga K, Nishie W, Akiyama M, Nagasaki A, Shimizu T, Shimizu H
    • Journal Title

      Br J Dermatol 160

      Pages: 465-468

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Novel mutation p.Gly59Arg in GJB6 encoding connexin 30 underlies plamoplantar keratoderma with pseudoainhum, knuckle pads and hearing loss2009

    • Author(s)
      Nemoto-Hasebe I, Akiyama M, Kudo S, Ishiko A, Tanaka A, Arita K, Shimizu H
    • Journal Title

      Br J Dermatol 161

      Pages: 452-455

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] FLG mutation p.Lys4021X in the C-terminal imperfect filaggrin repeat in Japanese patients with atopic eczema2009

    • Author(s)
      Nemoto-Hasebe I, Akiyama M, Nomura T, Sandilands A, McLean WH, Shimizu H
    • Journal Title

      Br J Dermatol 161

      Pages: 1387-1390

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Conradi-Hunermann-Happle syndrome with abnormal lamellar granule contents2009

    • Author(s)
      Akiyama M, Sakai K, Hayasaka K, Tabata N, Yamada M, Ujiie H, Shibaki A, Shimizu H
    • Journal Title

      Br J Dermatol 160

      Pages: 1335-1337

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Analysis of Taiwanese ichthyosis vulgaris families further demonstrates differences in FLG mutations between European and Asian populations2009

    • Author(s)
      Hsu CK, Akiyama M, Nemoto-Hasebe I, Nomura T, Sandilands A, Chao SC, Lee JY, Sheu HM, McLean WH, Shimizu H
    • Journal Title

      Br J Dermatol 161

      Pages: 448-451

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Genotoxic stress abrogates renewal of melanocyte stem cells by triggering their differentiation2009

    • Author(s)
      Inomata K, Aoto T, Binh NT, Okamoto N, Tanimura S, Wakayama T, Iseki S, Hara E, Masunaga T, Shimizu H, Nishimura EK
    • Journal Title

      Cell 137

      Pages: 1088-1099

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Collagen XVII participates in keratinocyte adhesion to collagen IV, and in p38MAPK-dependent migration and cell signaling.2009

    • Author(s)
      Qiao H, Shibaki A, Long HA, Wang G, Li Q, Nishie W, Abe R, Akiyama M, Shimizu H, McMillan JR.
    • Journal Title

      J Invest Dermatol 129

      Pages: 2288-95

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591332
  • [Journal Article] Current advances in gene the rapy for thetreatment of genodermatoses2009

    • Author(s)
      Long HA, McMillan JR, Qiao H, Akiyama M, Shimizu H
    • Journal Title

      Curr Gene Ther

      Volume: 9 Pages: 487-494

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390304
  • [Journal Article] Secondary syphilis mimicking warts in an HIV-positive patient2009

    • Author(s)
      Shinkuma S, Abe R, Nishimura M, Natsuga K, Fujita Y, Nomura T, Nishie W, Shimizu H
    • Journal Title

      Sex Transm Infect 85

      Pages: 484-484

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Spontaneous giant aneurysm of the superficial temporal artery : case report2009

    • Author(s)
      Kawabori M, Kuroda S, Nakayama N, Kenmotsu Y, Shimizu H, Tanino M, Iwasaki Y
    • Journal Title

      Neurol Med Chir 49

      Pages: 198-201

    • NAID

      10025947689

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] A randomized double-blind trial of intravenous immunoglobulin for pemphigus2009

    • Author(s)
      Amagai M, Ikeda S, Shimizu H, Iizuka H, Hanada K, Aiba S, Kaneko F, Izaki S, Tamaki K, Ikezawa Z, Takigawa M, Seishima M, Tanaka T, Miyachi Y, Katayama I, Horiguchi Y, Miyagawa S, Furukawa F, Iwatsuki K, Hide M, Tokura Y, Furue M, Hashimoto T, Ihn H, Fujiwara S, Nishikawa T, Ogawa H, Kitajima Y, Hashimoto K
    • Journal Title

      J Am Acad Dermatol 60

      Pages: 595-603

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] CD30-positive primary cutaneous anaplastic large-cell lymphoma and definite squamous cell carcinoma2009

    • Author(s)
      Yanagi T, Shimizu T, Kodama K, Nemoto-Hasebe I, Kasai M, Shimizu H
    • Journal Title

      Clin Exp Dermatol 34

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] A novel OSMR mutation in familial primary localized cutaneous amyloidosis in a Japanese family2009

    • Author(s)
      Arita K, Abe R, Baba K, McGrath JA, Akiyama M, Shimizu H
    • Journal Title

      J Dermatol Sci 55

      Pages: 64-65

    • NAID

      10025334319

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Autoantibodies against type XVII collagen C-terminal domain in patient with bullous pemphigoid associated with psoriasis vulgaris2009

    • Author(s)
      Inokuma D, Kodama K, Natsuga K, Kasai M, Abe M, Nishie W, Abe R, Hashimoto T, Shimizu H
    • Journal Title

      Br J Dermatol 160

      Pages: 451-454

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Birt-Hogg-Dube syndrome with clear-cell and oncocytic renal tumour and trichoblastoma associated with a novel FLCN mutation.2009

    • Author(s)
      Imada K, Dainichi T, Yokomizo A, Tsunoda T, Song YH, Nagasaki A, Sawamura D, Nishie W, Shimizu H, Fukagawa S, Urabe K, Furue M, Hashimoto T, Naito S
    • Journal Title

      Br J Dermatol 160

      Pages: 1350-1353

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390305
  • [Journal Article] Disseminated cutaneous Mycobacterium kansasii infection in an patient infected with the human immunodeficiency virus2009

    • Author(s)
      Nomura Y, Nishie W, Shibaki A, Ibata M, Shimizu H
    • Journal Title

      Clin Exp Dermatol 34

      Pages: 625-626

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Collagen XVII participates in keratinocyte adhesion to collagen IV, and in p38MAPK-dependent migration and cell signaling2009

    • Author(s)
      Qiao H, Shibaki A, Long HA, Wang G, Li Q, Nishie W, Abe R, Akiyama M, Shimizu H, McMillan JR
    • Journal Title

      J Invest Dermatol 129

      Pages: 2288-2295

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Collagen XVII Participates in Keratinocyte Adhesion to Collagen IV, and in p38MAPK-Dependent Migratin and Cell Signaling2009

    • Author(s)
      Qiao H, Shimizu H
    • Journal Title

      Journal of Investigative Dermatology (epub)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591291
  • [Journal Article] Immunological reconstitution after autologous hematopoietic stem cell transplantation in patients with systemic sclerosis : relationship between clinical benefits and intensity of immunosuppression2009

    • Author(s)
      Bohgaki T, Atsumi T, Bohgaki M, Furusaki A, Kondo M, Sato-Matsumura KC, Abe R, Kataoka H, Horita T, Yasuda S, Amasaki Y, Nishio M, Sawada K, Shimizu H, Koike T
    • Journal Title

      J Rheumatol 36

      Pages: 1240-1248

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] A severe and refractory case of anti-p200 pemphigoid resulting in multiple skin ulcers and scar formation2009

    • Author(s)
      Goto-Ohguchi Y, Nishie W, Akiyama M, Tateishi Y, Aoyagi S, Tsuji-Abe Y, Sawamura D, Ishii N, Hashimoto T, Shimizu H
    • Journal Title

      Dermatology 218

      Pages: 265-270

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Higher density of label-retaining cells in gingival epithelium2009

    • Author(s)
      Asaka T, Akiyama M, Kitagawa Y, Shimizu H
    • Journal Title

      J Dermatol Sci 55

      Pages: 132-134

    • NAID

      10025560846

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] ABCA12 is a major causative gene for non-bullous congenital ichthyosiform erythroderma2009

    • Author(s)
      Sakai K, Akiyama M, Yanagi T, McMillan JR, Suzuki T, Tsukamoto K, Sugiyama H, Hatano Y, Hayashitani M, Takamori K, Nakashima K, Shimizu H
    • Journal Title

      J Invest Dermatol 129

      Pages: 2306-2309

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Conradi-Hunermann-Happle syndrome with abnormal lamellar granule contents2009

    • Author(s)
      Akiyama M, Sakai K, Hayasaka K, TabataN, Yamada M, Ujiie H, Shibaki A, Shimizu H
    • Journal Title

      Br J Dermatol

      Volume: 160 Pages: 1335-1337

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390304
  • [Journal Article] A novel humanized neonatal autoimmune blistering skin disease model induced by maternally transferred antibodies2009

    • Author(s)
      Nishie W, Sawamura D, Natsuga K, Shinkuma S, Goto M, Shibaki A, Ujiie H, Olasz E, Yancey KB, Shimizu H
    • Journal Title

      J Immunol 183

      Pages: 4088-4093

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Scleroedema adultorum associated with sarcoidosis2009

    • Author(s)
      Inokuma D, Sawamura D, Shibaki A, Abe R, Shimizu H
    • Journal Title

      Clin Exp Dermatol 34

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Bowen's disease of the nail matrix presenting as melanonychia : detection of human papillomavirus type 562009

    • Author(s)
      Inokuma D, Aoyagi S, Saito N, Iitani MM, Homma E, Hamasaka K, Shimizu H
    • Journal Title

      Acta Derm Venereol 89

      Pages: 638-639

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Embryonic hair follicle fate change by augmented{beta}-catenin through Shh and Bmp signaling2009

    • Author(s)
      Suzuki K, Yamaguchi Y, Villacorte M, Mihara K, Akiyama M, Shimizu H, Taketo MM, Nakagata N, Tsukiyama T, Yamaguchi TP, Birchmeier W, Kato S, Yamada G
    • Journal Title

      Development 136

      Pages: 367-372

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Novel mutation p. Gly59Arg in GJB6 encoding connexin 30 underlies palmoplantar keratoderma with pseudoainhum, knuckle pads and hearing loss2009

    • Author(s)
      Nemoto-Hasebe I, Akiyama M, Kudo S, Ishiko A, Tanaka A, Arita K, Shimizu H
    • Journal Title

      B J Dermatol

      Volume: 161 Pages: 452-455

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390304
  • [Journal Article] Progressive Refractory Ulcer of the Nipple : A Quiz2009

    • Author(s)
      Nomura Y, Akiyama M, Nishie W, SHimizu H
    • Journal Title

      Acta Derm Venereol 89

      Pages: 445-447

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Squamous cell carcinoma of the auricle with rhabdoid features2009

    • Author(s)
      Aoyagi S, Hata H, Iitani MM, Homma E, Inokuma D, Shimizu H
    • Journal Title

      J Cutan Pathol 36

      Pages: 919-921

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Keratinocyte-/fibroblast-targeted rescue of Co17a1-disrupted mice and generation of an exact dystrophic epidermolysis bullosa model using a-human COL7A1 mutation2009

    • Author(s)
      Ito K, Sawamura D, Goto M, Nakamura H, Nishie W, Sakai K, Natsuga K, Shinkuma S, Shibaki A, Uitto J, Denton CP, Nakajima O, Akiyama M, Shimizu H
    • Journal Title

      Am J Pathol 175

      Pages: 2508-2517

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Keratinocyte-/fibroblast-targeted rescue of Col7a1-disrupted mice and generation of an exact dystrophic epidermolysis bullosa model using a human COL7A1 mutation.2009

    • Author(s)
      Ito K, Sawamura D, Goto M, Nakamura H, Nishie W, Sakai K, Natsuga K, Shinkuma S, Shibaki A, Uitto J, Denton CP, Nakajima O, Akiyama M, Shimizu H
    • Journal Title

      Am J Pathol, 175

      Pages: 2508-2517

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390305
  • [Journal Article] Collagen XVII Participates in Keratinocyte Adhesion to Collagen IV, and in P38mapk-Dependent Migration and cell Signaling2009

    • Author(s)
      Qiao H, Shimizu H
    • Journal Title

      Journal of Investigative Dermatology, epub

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591291
  • [Journal Article] Harlequin ichthyosis model mouse reveals alveolar collapse and fetal skin barrier defects2008

    • Author(s)
      Yanagi T, Akiyama M, Nishihara H, Sakai K, Nishie W, Tanaka S, Shimizu H
    • Journal Title

      Hum Mol Genet

      Volume: 17 Pages: 3075-3083

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390304
  • [Journal Article] Transformation-specific matrix metalloproteinases (MMP)-7 and MMP-13 are expressed by tumour cells in epidermolysis bullosa-associated squamous cell carcinomas.2008

    • Author(s)
      Kivisaari AK, Kallajoki M, Mirtti T, McGrath JA, Bauer JW, Weber F, Konigova R, Sawamura D, Sato-Matsumura KC, Shimizu H, Csikos M, Sinemus K, Beckert W, Kahari VM
    • Journal Title

      Br J Dermatol 158

      Pages: 778-1785

    • Data Source
      KAKENHI-PROJECT-20390305
  • [Journal Article] Keratitis-Ichthyosis-Deafness syndrome lacking subjective hearing impairment2008

    • Author(s)
      Nemoto-Hasebe I, Akiyama M, Yanada N, Inoue Y, Chizu T, Shimizu H
    • Journal Title

      Acta Dermato-Venereol

      Volume: 88 Pages: 406-408

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390304
  • [Journal Article] Clinical and Genetic analysis of Fabry disease : report of 6 cases including 3 heterozygous females.2008

    • Author(s)
      Nagasaki A, Nishie W, Sato K, Oba I, Noguchi E, Akitsu H, Sawamura D, Shimizu H
    • Journal Title

      J Dermatol Sci 52

      Pages: 61-64

    • Data Source
      KAKENHI-PROJECT-20390305
  • [Journal Article] CGI-58 is an alpha/beta hydrolase within lipid transporting lamellar granules of differentiated keratinocytes2008

    • Author(s)
      Akiyama M, Sakai K, Takayama C, Yanagi T, Yamanaka Y, McMillan JR, Shimizu H
    • Journal Title

      Am J Pathol

      Volume: 173 Pages: 1349-60

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390304
  • [Journal Article] Mild recessive bullous congenital ichthyosiform erythroderma due to a novel homozygous keratin 10 nonsense mutation2008

    • Author(s)
      Tsubota A, Akiyama M, Kanitakis J, Sakai K, Nomura T, Claudy A, Shimizu H
    • Journal Title

      J Invest Dermatol

      Volume: 128 Pages: 1648-1652

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390304
  • [Journal Article] Type XVII collagen is a key player in tooth enamel formation2008

    • Author(s)
      Asaka T, Shimizu H
    • Journal Title

      American Journal of Pathology 174(1)

      Pages: 91-100

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591291
  • [Journal Article] An update on molecular aspects of the non-syndromic ichthyoses2008

    • Author(s)
      Akiyama M, Shimizu H
    • Journal Title

      Exp Dermatol

      Volume: 17 Pages: 373-382

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390304
  • [Journal Article] Mesenchymal stem cells are recruited into wounded skin and contribute to wound repair by transdifferentiation into multiple skin cell type.2008

    • Author(s)
      Sasaki M, Abe R, Fujita Y, Ando S, Inokuma D, Shimizu H.
    • Journal Title

      J Immunol 180

      Pages: 2581-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591332
  • [Journal Article] Novel compound heterozygous nonsense and missense ABCA12 mutations lead to non-bullous congenital ichthyosiformerythroderma2008

    • Author(s)
      Akiyama M, Sakai K, Hatamochi A, Yamazaki S, McMillan JR, Shimizu H
    • Journal Title

      Br J Dermatol

      Volume: 158 Pages: 864-867

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390304
  • [Journal Article] DNA-based prenatal exclusion of harlequin ichthyosis2008

    • Author(s)
      Yanagi T, Akiyama M, Sakai K, Nagasaki A, Ozawa N, Kosaki R, Sago H, Shimizu H
    • Journal Title

      J Am Acad Dermatol

      Volume: 58 Pages: 653-656

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390304
  • [Journal Article] Specific filaggrin mutations cause ichthyosis vulgaris and are significantly associated with atopic dermatitis in Japan2008

    • Author(s)
      Nomura T, Akiyama M, Sandilands A, Nemoto-Hasebe I, Sakai K, Nagasaki A, Ota M, Hata H, Evans AT, Palmer CAN, Shimizu H, McLean WHI
    • Journal Title

      J Invest Dermatol

      Volume: 128 Pages: 1436-1441

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390304
  • [Journal Article] Unique mutations in the filaggrin gene in Japanese patients with ichthyosis vulgaris and atopic dermatitis2007

    • Author(s)
      Nomura T, Sandilands A, Akiyama M, Sakai K, Ota M, Sugiura H, Yamamoto K, Sato H, Smith FJD, McLean WHI, Shimizu H.
    • Journal Title

      J Allergy Clin Immunol 119

      Pages: 434-440

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390310
  • [Journal Article] J Allergy Clin Immunol2007

    • Author(s)
      Nomura T, Sandilands A, Akiyama M, Sakai K, Ota M, Sugiura H, Yamamoto K, Sato H, Smith FJD, McLean WHI, Shimizu H.
    • Journal Title

      119

      Pages: 434-440

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390310
  • [Journal Article] Expression of the keratinocyte lipid transporter ABCA12 in developing and reconstituted human epidermis2007

    • Author(s)
      Yamanaka Y, Akiyama M, Sugiyama-Nakagiri Y, Sakai K, Goto M, McMillan JR, Ota M, Sawamura D, Shimizu H
    • Journal Title

      Am J Pathol 171

      Pages: 43-52

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390310
  • [Journal Article] DNA-based prenatal diagnosis of harlequin ichthyosis and characterization of ABCA12 mutation consequences2007

    • Author(s)
      Akiyama M, Titeux M, Sakai K, McMillan JR, Tonasso L, Calvas P, Jossic F, Hovnanian A, Shimizu H.
    • Journal Title

      J Invest Dermatol 127

      Pages: 568-573

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390310
  • [Journal Article] J Invest Dermatol2007

    • Author(s)
      Akiyama M, Titeux M, Sakai K, McMillan JR, Tonasso L, Calvas P, Jossic F, Hovnanian A, Shimizu H.
    • Journal Title

      127

      Pages: 568-573

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390310
  • [Journal Article] Am J Pathol2007

    • Author(s)
      Yamanaka Y, Akiyama M, Sugiyama-Nakagiri Y, Sakai K, Goto M, McMillan JR, Ota M, Sawamura D, Shimizu H
    • Journal Title

      171

      Pages: 43-52

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390310
  • [Journal Article] Targeted skipping of a single exon harboring a premature termination codon mutation : Implications and potential for gene correction therapy for selective dystrophic epidermolysis bullosa patients.2006

    • Author(s)
      Goto M, Sawamura D, Nishie W, Sakai K, McMillan JR, Akiyama M, Shimizu H
    • Journal Title

      J Invest Dermatol 126・12

      Pages: 2614-1620

    • Data Source
      KAKENHI-PROJECT-18390309
  • [Journal Article] Fibroblasts Show More Potential as Target Cells than Keratinocytes in COL7A1Gene Therapy of Dystrophic Epidermolysis Bullosa.2006

    • Author(s)
      Goto M, Sawamura D, Ito K, Abe M, Nishie W, Sakai K, Shibaki A, Akiyama M, Shimizu H
    • Journal Title

      J Invest Dermatol in press

    • Data Source
      KAKENHI-PROJECT-17014004
  • [Journal Article] A unique monoclonal antibody 29A staining the cytoplasm of amniotic epithelial in the placenta and cutaneous basement membrane zone.2006

    • Author(s)
      Ota M, Sawamura D, Yokota Y, Ueda M, Horiguchi Y, Kodama K, Goto M, Shimizu H
    • Journal Title

      J Dermatol Sci 42・1

      Pages: 23-29

    • Data Source
      KAKENHI-PROJECT-18390309
  • [Journal Article] Analysis of the COL17A1 in non-Herlitz junctional epidermolysis bullosa and amelogenesis imperfecta.2006

    • Author(s)
      Nakamura H, Sawamura D, Goto M, Nakamura H, Kida M, Ariga T, Sakiyama Y, Tomizawa K, Mitsui M, Tamaki T, Shimizu H
    • Journal Title

      Int J Mol Med 18・2

      Pages: 333-337

    • Data Source
      KAKENHI-PROJECT-18390309
  • [Journal Article] A unique monoclonal antibody 29A stains the cytoplasm of amniotic epithelia andcutaneous basement membrane.2006

    • Author(s)
      Ota M, Sawamura D, Yokota K, Ueda M, Horiguchi Y, Kodama K, Goto M, Shimizu H.
    • Journal Title

      J Dermatol Sci 42(1)

      Pages: 23-29

    • Data Source
      KAKENHI-PROJECT-17014004
  • [Journal Article] COL7A1 mutation G2037E causes epidermal retention of type VII collagen.2006

    • Author(s)
      Sawamura D, Sato-Matsumura K, Shibata S, Tashiro A, Frue M, Goto M, Akiyama M, Nakamura H, Shimizu H
    • Journal Title

      J Hum Genet 51・5

      Pages: 418-420

    • NAID

      10019167846

    • Data Source
      KAKENHI-PROJECT-18390309
  • [Journal Article] Expression of RNA-binding protein Musashi in hair follicle development and haircycle progression.2006

    • Author(s)
      Sugiyama-Nakagiri Y, Akiyama M, Shibata S, Okano H, Shimizu H
    • Journal Title

      Am J Pathol 168(1)

      Pages: 80-92

    • Data Source
      KAKENHI-PROJECT-17209038
  • [Journal Article] A unique monoclonal antibody 29A stains the cytoplams of amniotic epithelia and cutaneous basement membrane.2006

    • Author(s)
      Ota M, Sawamura D, Yokota K, Ueda M, Horiguchi Y, Kodama K, Goto M, Shimizu H.
    • Journal Title

      J Dermatol Sci 42(1)

      Pages: 23-29

    • Data Source
      KAKENHI-PROJECT-17209038
  • [Journal Article] Possible role of endoplasmic reticulum stress in the pathogenesis of Darier's disease.2006

    • Author(s)
      Onozuka T, Sawamura D, Goto M, Yokota K, Shimizu H
    • Journal Title

      J Dermatol Sci 41(3)

      Pages: 217-220

    • NAID

      10020550283

    • Data Source
      KAKENHI-PROJECT-17209038
  • [Journal Article] Childhood epidermolysis bullosa acquisita with autoantibodies against the noncollagenous 1 an d 2 domains of type VII collagen : case report and review of the literature.2006

    • Author(s)
      Mayuzumi M, Akiyama M, Nishie W, Ukae S, Abe M, Sawamura D, Hashimoto T, Shimizu H
    • Journal Title

      Br J Dermatol 155・5

      Pages: 1048-1052

    • Data Source
      KAKENHI-PROJECT-18390309
  • [Journal Article] Fibroblasts show more potential target cells than keratinocytes for COL7A1 gene therapy of dystrophic epidermolysis bullosa.2006

    • Author(s)
      Goto M, Sawamura D, Ito K, Abe M, Nishie W, Sakai K, Shibaki A, Akiyama M, Shimizu H
    • Journal Title

      J Invest Dermatol 126・4

      Pages: 766-772

    • Data Source
      KAKENHI-PROJECT-18390309
  • [Journal Article] Epidermolysis bullosa simplex in orientals : genetic studies in 19 cases.2006

    • Author(s)
      Yasukawa K, Sawamura D, Goto M, Nakamura H, Jung SY, Kim SC, Shimizu H
    • Journal Title

      Br J Dermatol in press

    • Data Source
      KAKENHI-PROJECT-17014004
  • [Journal Article] Expression of RNA-binding protein Musashi in hair follicle development and haircycle progression.2006

    • Author(s)
      Sugiyama-Nakagiri Y, Akiyama M, Shibata S, Okano H, Shimizu H
    • Journal Title

      Am J Pathol 168(1)

      Pages: 80-92

    • Data Source
      KAKENHI-PROJECT-17014004
  • [Journal Article] A novel indel COL7A1 mutation 8068de117insGA causes dominant dystrophic epidermolysis bullosa.2006

    • Author(s)
      Sawamura D, NiizeKi H, Miyagawa S, Shinkuma S, Shimizu H
    • Journal Title

      Br J Dermatol 154・5

      Pages: 995-997

    • Data Source
      KAKENHI-PROJECT-18390309
  • [Journal Article] A novel ABCA12 mutation 3270deIT causes harlequin ichthyosis.2006

    • Author(s)
      Akiyama M, Sakai K, Wolff G, Hausser I, McMillan JR, Sawamura D, Shimizu H
    • Journal Title

      Br J Dermatol 155・5

      Pages: 1064-1066

    • Data Source
      KAKENHI-PROJECT-18390310
  • [Journal Article] Novel ALDH3A2 heterozygous mutations in a Japanese family of Sjogren-Larsson syndrome2006

    • Author(s)
      Sakai K, Akiyama M, Watanabe T, Sanayama K, Sugita K, Takahashi M, Suehiro K, Yorifuji K, Shibaki A, Shimizu H
    • Journal Title

      J Invest Dermatol 126・11

      Pages: 2545-2547

    • Data Source
      KAKENHI-PROJECT-18390310
  • [Journal Article] Epidermolysis bullosa simplex in Oriental; genetic studies in 19 patients.2006

    • Author(s)
      Yasukawa K, Sawamura D, Jung Sung-Yong, Goto M, Nakamura H, Kim S-C, Shimizu H
    • Journal Title

      Br J Dermatol 155・2

      Pages: 313-317

    • Data Source
      KAKENHI-PROJECT-18390309
  • [Journal Article] Compound heterozygous mutations including a de novo missense mutation in ABCA12 led to a case of harlequin ichthyosis with moderate clinical severity.2006

    • Author(s)
      Akiyama M, Sakai K, Sugiyama-Nakagiri Y, Yamanaka Y, McMillan JR, Sawamura D, Niizeki H, Miyagawa S, Shimizu H
    • Journal Title

      J Invest Dermatol 126・7

      Pages: 1518-1523

    • NAID

      120000971664

    • Data Source
      KAKENHI-PROJECT-18390309
  • [Journal Article] Glycine substitution mutations of different amino acids at the same codon in COL7A1 cause different modes of dystrophic epidermolysis bullosa inheritance.2006

    • Author(s)
      Sawamura D, Mochitomi Y, Kanzaki T, Nakamura N, Shimizu H
    • Journal Title

      Br J Dermatol 155・4

      Pages: 834-837

    • Data Source
      KAKENHI-PROJECT-18390309
  • [Journal Article] Possible role of endoplasmic reticulum stress in the pathogenesis of Darier'sdisease.2006

    • Author(s)
      Onozuka T, Sawamura D, Goto M, Yokota K, Shimizu H
    • Journal Title

      J Dermatol Sci 41(3)

      Pages: 217-220

    • Data Source
      KAKENHI-PROJECT-17014004
  • [Journal Article] Tissue regeneration using macrophage migration inhibitory factor-impregnatedgelatin microbeads in cutaneous wounds.2005

    • Author(s)
      Zhao Y, Shimizu T, Nishihira J, Koyama Y, Kushibiki T, Honda A, Watanabe H, Abe R, Tabata Y, Shimizu H.
    • Journal Title

      Am J Pathol 167(6)

      Pages: 1519-1529

    • Data Source
      KAKENHI-PROJECT-17014004
  • [Journal Article] Tissue regeneration using macrophage migration inhibitory factor-impregnatedgelatin microbeads in cutaneous wounds.2005

    • Author(s)
      Zhao Y, Shimizu T, Nishihira J, Koyama Y, Kushibiki T, Honda A, Watanabe H, Abe R, Tabata Y, Shimizu H.
    • Journal Title

      Am J Pathol 167(6)

      Pages: 1519-1529

    • Data Source
      KAKENHI-PROJECT-17209038
  • [Journal Article] Type XVII collagen ELISA indices significantly decreased after bullous pemphigoid remission

    • Author(s)
      Kusajima E, Akiyama M, Sato M, Natsuga K, Shimizu H
    • Journal Title

      Int J Dermatol (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Nanoparticle albumin-bound paclitaxel can be useful agent to advanced primary mucinous carcinoma of the skin.

    • Author(s)
      Homma E, Hata H, Aoyagi S, Shimizu H
    • Journal Title

      Dermatologic therapy

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670494
  • [Journal Article] Transglutaminasel Preferred substrate peptide K5 is an efficient tool in diagnosis of lamellar ichthyosis

    • Author(s)
      Akiyama M, Sakai K, Yanagi T, Fukushima S, Ihn H, Hitomi K, Shimizu H
    • Journal Title

      Am J Pathol (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Dermoscopic Features of Plasma Cell Cheilitis and Actinic Cheilitis

    • Author(s)
      Ito T, Natsuga K, Tanimura S, Aoyagi S, Shimizu H
    • Journal Title

      Acta Derm Venereol

      Volume: (in press)

    • DOI

      10.2340/00015555-1795

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670494
  • [Journal Article] An Indian family with Sjogren-Larsson syndrome caused by a novel ALDH3A2 mutation

    • Author(s)
      Sakai K, Akiyama M, Yanagi T, Nampoothiri S, Mampilly T, V S, Shimizu H
    • Journal Title

      Int J Dermatol (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Extremely severe palmoplantar hyperkeratosis in a generalized epidermolytic hyperkeratosis patient with a keratin 1 gene mutation

    • Author(s)
      Osawa R, Akiyama M, Izumi K, Ujiie H, Sakai K, Nemoto-Hasebe I, Yanagi T, Koizumi H, Shimizu H
    • Journal Title

      J Am Acad Dermatol (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Two cases of cutaneous sporotrichosis in continental/microthermal climatezone : global warming alert?

    • Author(s)
      Inokuma D, Shibaki A, Shimizu H
    • Journal Title

      Clin Exp Dermatol (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Long-term follow-up of cultured epidermal autograft in a recessive dystrophic epidermolysis bullosa patient

    • Author(s)
      Satoru Shinkuma、Daisuke Sawamura、Yasuyuki Fujita、Hiroyuki Kawasaki、Hiroyuki Nakamura、Masukazu Inoie、ataru Nishie、Hiroshi Shimizu
    • Journal Title

      Acta Dermato-Venereologica

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659516
  • [Journal Article] Paper-Based ELISA for the Detection of Autoimmune Antibodies in Body Fluid-The Case of Bullous Pemphigoid

    • Author(s)
      Hsu CK, Huang HY, Chen WR, Nishie W, Ujiie H, Natsuga K, Fan ST, Wang HK, Lee JY, Tsai WL, Shimizu H, Cheng CM
    • Journal Title

      Anal Chem

      Volume: (in press)

    • DOI

      10.1021/ac500835k

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670494
  • [Journal Article] Solitary tumor on the neck

    • Author(s)
      Horie K, Abe R, Murata J, Nomura T, Shimizu H
    • Journal Title

      Acta Dermato Venereol

      Volume: (in press)

    • DOI

      10.2340/00015555-1792

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670494
  • [Journal Article] Tubular apocrine adenoma clinically and dermoscopically mimicking basal cell carcinoma

    • Author(s)
      Ito T, Nomura T, Fujita Y, Abe R, Shimizu H
    • Journal Title

      J Am Acad Dermatol

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670494
  • [Journal Article] Three-base deletion mutation c. 120_122delGTT in ATP2A2 leads to the unique phenotype of comedonal Darier disease

    • Author(s)
      Tsuruta D, Akiyama M, Ishida-Yamamoto A, Imanishi H, Mizuno N, Sowa J, Kobayashi H, Ishii M, Kurokawa I, Shimizu H
    • Journal Title

      Br J Dermatol (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Ultrasound B-mode and Elastographic Findings of Angiomatoid Fibrous Histiocytoma.

    • Author(s)
      Hata H, Natsuga K, Homma E, Aoyagi S, Shimizu H
    • Journal Title

      Clin Exp Dermatol

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670494
  • [Journal Article] Nanoparticle albumin-bound paclitaxel can be useful agent to advanced primary mucinous carcinoma of the skin

    • Author(s)
      Ohguchi Y, Nomura T, Suzuki S, Mizuno O, Nomura Y, Nomoto-Hasebe I, Okamoto H, Sandilands A, Akiyama M, McLean WH, Shimizu H
    • Journal Title

      Dermatologic therapy

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670494
  • [Journal Article] Topical application of anti-angiogenic peptides based on pigment epithelium-derived factor can improve psoriasis

    • Author(s)
      Abe R, Yamagishi SI, Fujita Y, Hoshina D, Sasaki M, Nakamura K, Matsui T, Shimizu T, Bucala R, Shimizu H
    • Journal Title

      J Dermatol Sci (in press)

    • NAID

      10027399968

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Two cases of pseudolymphoma on the lips

    • Author(s)
      Haga N, Nishie W, Hata H, Miyauchi T, Muramatsu K, Kitamura S, Osawa R, Shimizu H
    • Journal Title

      Br J Dermatol

      Volume: (in press)

    • DOI

      10.1111/bjd.12837

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24791130, KAKENHI-PROJECT-25670494
  • [Journal Article] Fibroblasts Show More Potential as Target Cells than Keratinocytes in COL7A1Gene Therapy of Dystrophic Epidermolysis Bullosa.

    • Author(s)
      Goto M, Sawamura D, Ito K, Abe M, Nishie W, Sakai K, Shibaki A, Akiyama M, Shimizu H
    • Journal Title

      J Invest Dermatol (in press)

    • Data Source
      KAKENHI-PROJECT-17209038
  • [Journal Article] Revised nomenclature and classification of inherited ichthyoses : Results of the First Ichthyosis

    • Author(s)
      Vinzenz O, Gianluca T, Akiyama M, Claudine B-B, Christine B, Emmanuelle B, Philippe C, John JD, Peter E, Judith F, Philip F, Michal G, John H, Hashimoto T, Ingrid H, Hans CH, Daniel H, Alain H, Ishida-Yamamoto A, Withold KJ, Sancy L, Irene L, Juliette M-H, Leonhard M, Fanny M-P, Amy SP, Gabriele R, Matthias S, Shimizu H, Eli S, Maurice vS, Alain T, Jorge RT, Pierre V, Anders V, Mary W, Heiko T
    • Journal Title

      J Am Acad Dermatol (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] MUC5AC expression correlates with invasiveness and progression of extramammary Paget's disease

    • Author(s)
      Hata H, Abe R, Hoshina D, Saito N, Homma E, Aoyagi S, Shimizu H
    • Journal Title

      J Eur Acad Dermatol Venereol

      Volume: (in press)

    • DOI

      10.1111/ced.12314

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670494
  • [Journal Article] Aleukemic leukemia cutis with extensive bone involvement

    • Author(s)
      Iitani MM, Abe R, Yanagi T, Hamasaka A, Tateishi Y, Abe Y, Ito M, Kondo T, Kubota K, Shimizu H
    • Journal Title

      J Am Acad Dermatol (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Journal Article] Epidermolysis bullosa simplex in orientals : genetic studies in 19 cases.

    • Author(s)
      Yasukawa K, Sawamura D, Goto M, Nakamura H, Jung SY, Kim SC, Shimizu H
    • Journal Title

      Br J Dermatol (in press)

    • Data Source
      KAKENHI-PROJECT-17209038
  • [Journal Article] Primary mucinous carcinoma of the skin with in-transit metastasis

    • Author(s)
      Homma E, Hata H, Aoyagi S, Shimizu H
    • Journal Title

      J Eur Acad Dermatol Venereol

      Volume: (in press)

    • DOI

      10.1111/jdv.12533

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670494
  • [Presentation] 体細胞組換えによるrevertant mosaicismを認めたロリクリン角皮症の2家系2019

    • Author(s)
      乃村俊史,鈴木翔多朗,宮内俊成,竹田真依,藤田靖幸,西江 渉,秋山真志,山本明美,清水 宏
    • Organizer
      第83回日本皮膚科学会東京・東部合同学術大会
    • Data Source
      KAKENHI-PROJECT-19H03679
  • [Presentation] Mitotic recombination underlies frequent revertant mosaicism in loricrin keratoderma2019

    • Author(s)
      乃村俊史,鈴木翔多朗,宮内俊成,竹田真依,藤田靖幸,西江 渉,秋山真志,山本明美,清水 宏
    • Organizer
      日本人類遺伝学会第64回大会
    • Data Source
      KAKENHI-PROJECT-19H03679
  • [Presentation] Frameshift mutations in different exons of Col17a1 lead to distinctive phenotype of junctional epidermolysis bullosa model mice.2019

    • Author(s)
      Nguyen Hong Ha, Shinkuma Satoru, Ansai Osamu, Kabata Yudai, Takashima Shota, Mori Masashi, Ikawa Masahito, Shimizu Hiroshi, Abe Riichiro
    • Organizer
      The 44th Annual Meeting of the Japanese Society for Investigative Dermatology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H01572
  • [Presentation] 体細胞組換えによるrevertant mosaicismを認めたロリクリン角皮症の2家系2019

    • Author(s)
      乃村俊史,鈴木翔多朗,宮内俊成,竹田真依,藤田靖幸,西江 渉,秋山真志,山本明美,清水 宏
    • Organizer
      第83回日本皮膚科学会東京・東部合同学術大会
    • Data Source
      KAKENHI-PROJECT-17H06271
  • [Presentation] Mitotic recombination underlies frequent revertant mosaicism in loricrin keratoderma2019

    • Author(s)
      乃村俊史,鈴木翔多朗,宮内俊成,竹田真依,藤田靖幸,西江 渉,秋山真志,山本明美,清水 宏
    • Organizer
      日本人類遺伝学会第64回大会
    • Data Source
      KAKENHI-PROJECT-17H06271
  • [Presentation] Efficient reframed gene therapy for recessive dystrophic epidermolysis bullosa using CRISPR/Cas9.2018

    • Author(s)
      Shota Takashima, Satoru Shinkuma, Yasuyuki Fujita, Toshifumi Nomura, Hideki Nakamura, Hiroshi Shimizu
    • Organizer
      The 7th International Investigative Dermatology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H01572
  • [Presentation] Differences in collagen XVII expression between skin and oral mucosa affect the pathogenicity of pemphigoid IgG2018

    • Author(s)
      .Kamaguchi M, Iwata H, Ujiie H, Natsuga K, Nishie W, Asaka T, Shimizu H, Kitagawa Y.
    • Organizer
      14th Biennial Congress of the European Association of Oral Medicine Gotenbrug, Sweden.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10120
  • [Presentation] Ichthyosis with confettiの一例2018

    • Author(s)
      乃村俊史、清水宏
    • Organizer
      第466回日本皮膚科学会大阪地方会
    • Data Source
      KAKENHI-PROJECT-17H06271
  • [Presentation] Cultured epidermal autograft from clinically revertant skin in recessive dystrophic epidermolysis bullosa.2018

    • Author(s)
      Fujita Y, Matsumura W, Shinkuma S, Takashima S, Suzuki S, Nomura T, Nakamura H, Inoie M, Shimizu H.
    • Organizer
      Internatinal Investigative Derematology 2018. Orlando, Florida.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10120
  • [Presentation] Chromosomal inversions as a hidden disease-modifying factor2017

    • Author(s)
      Nomura T, Suzuki S, Miyauchi T, Takeda M, Fujita Y, Nishie W, Akiyama M, Shimizu H
    • Organizer
      The 47th Annual European Society for Dermatological Research Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06271
  • [Presentation] 診断に難渋した先天性魚鱗癬の1例2017

    • Author(s)
      乃村俊史, 鈴木翔多朗, 宮内俊成, 竹田真依, 藤田靖幸, 西江渉, 秋山真志, 清水宏
    • Organizer
      第32回角化症研究会
    • Data Source
      KAKENHI-PROJECT-17H06271
  • [Presentation] Long lasting epithelization after cultured epidermal autograft with revertant mosaicism in recessive dystrophic epidermolysis bullosa2017

    • Author(s)
      Matsumura W, Fujita Y, Takashima S, Nakayama C, Ujiie I, Shinkuma S, Nakamura H, Sawamura D, Inoie M, Shimizu H
    • Organizer
      DEBRA International Congress 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10120
  • [Presentation] Normal appearance of epidermal basement membrane zone in nail-patella syndrome patients2017

    • Author(s)
      Shinkuma S, Nakamura H, Takashima S, Nomura T, Fujita Y, Matsumura K, Shimizu H, Abe R
    • Organizer
      The 42nd Annual Meeting of the Japanese Society for Investigative Dermatology
    • Data Source
      KAKENHI-PROJECT-16K10120
  • [Presentation] 魚鱗癬と掌蹠角化症:症例から見えてきたこと2017

    • Author(s)
      乃村俊史、清水宏
    • Organizer
      群馬皮膚科セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K09738
  • [Presentation] Two families of nail-patella syndrome with splice site mutations2017

    • Author(s)
      Shinkuma S, Nakamura H, Takashima S, Nomura T, Fujita Y, Hasegawa S, Sato-Matsumura K, Shimizu H, Abe R
    • Organizer
      The 47th Annual European Society for Dermatological Research Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10120
  • [Presentation] Chromosomal inversions as a hidden disease-modifying factor2017

    • Author(s)
      Nomura T, Suzuki S, Miyauchi T, Takeda M, Fujita Y, Nishie W, Akiyama M, Shimizu H
    • Organizer
      The 47th Annual Meeting of the European Society for Dermatological Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09738
  • [Presentation] 診断に難渋した先天性魚鱗癬の1例2017

    • Author(s)
      乃村俊史,鈴木翔多朗,宮内俊成,竹田真依,藤田靖幸,西江 渉,秋山真志,清水 宏
    • Organizer
      第32回角化症研究会
    • Data Source
      KAKENHI-PROJECT-15K09738
  • [Presentation] Abnormalities in laminin-332 have post-translational effects on laminin γ22017

    • Author(s)
      Natsuga K, Nishie W, Watanabe M, Nakamura H, Shinkuma S, Shimizu H
    • Organizer
      EB2017 - 5th World Conference of EB Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10120
  • [Presentation] Gene-edition targeting mutation site recovers null-expression of type VII collagen caused by frameshift mutation via non-homologous end joining in recessive dystrophic epidermolysis bullosa.2017

    • Author(s)
      Takashima S, Shinkuma S, Fujita Y, Nomura T, Ujiie H, Abe R, Shimizu H
    • Organizer
      The 73rd Annual Meeting of the Society for Investigative Dermatology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H01572
  • [Presentation] Long lasting epithelization after cultured epidermal autograft with revertant mosaicism in recessive dystrophic epidermolysis bullosa.2017

    • Author(s)
      Matsumura W, Fujita Y, Nakamura H, Nishie W, Shinkuma S, Ujiie I, Nakayama C, Takashima S, Sawamura D, Inoie M, Shimizu H
    • Organizer
      DebRA International 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H01572
  • [Presentation] The development of mesenchymal stem/stromal cellsfrom keratinocyte-derived induced pluripotent stem cells (iPSCs).2017

    • Author(s)
      Chihiro Nakayama, Yasuyuki Fujita, Wakana Matsumura, Shota Takashima, Satoru Shinkuma, Toshifumi Nomura, Riichiro Abe, Hiroshi Shimizu
    • Organizer
      The 42nd Annual Meeting of the Japanese Society for Investigative Dermatology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09753
  • [Presentation] A case of recessive dystrophic epidermolysis bullosa with a novel c.6885_6898del14 mutation.2017

    • Author(s)
      Shinkuma S, Masunaga T, Miyawaki S, Takashima S, Natsuga K, Nomura T, Fujita Y, Nakamura H, Shimizu H
    • Organizer
      The 76th Annual Meeting of the Society for Investigative Dermatology.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10120
  • [Presentation] Clinical management and experimental findings in epidermolysis bullosa.2016

    • Author(s)
      Yasuyuki Fujita, Hiroshi Shimizu
    • Organizer
      Asia-Pacific Combined Dermatology Research 2016 Conference
    • Place of Presentation
      Noosa, Australia
    • Year and Date
      2016-08-25
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09753
  • [Presentation] 皮膚基底膜構築における17型コラーゲン細胞外領域切断の生理機能の解析2016

    • Author(s)
      西村真智子, 西江渉, 新熊悟, 夏賀健, 中村秀樹, 白藤宜紀, 岩月啓氏, 澤村大輔, 清水宏
    • Organizer
      第407回日本皮膚科学会北海道地方会
    • Place of Presentation
      札幌医大、札幌市
    • Data Source
      KAKENHI-PROJECT-16K10120
  • [Presentation] 自然治癒する魚鱗癬の1例2016

    • Author(s)
      乃村俊史,清水宏
    • Organizer
      日本皮膚科学会岩手地方会学術大会第373回例会
    • Place of Presentation
      盛岡市民文化ホール (岩手県・盛岡市)
    • Year and Date
      2016-02-06
    • Data Source
      KAKENHI-PROJECT-15H04780
  • [Presentation] FLG変異とフタル酸エステル曝露による児のアトピー性皮膚炎への影響:北海道スタディ2016

    • Author(s)
      アイツバマイゆふ, 荒木敦子, 乃村俊史, 河合俊夫, 坪井樹, 叢石, 宮下ちひろ, 池野多美子, 清水宏, 岸玲子
    • Organizer
      第86回日本衛生学会学術総会
    • Place of Presentation
      旭川市民文化会館(北海道・旭川市)
    • Year and Date
      2016-05-11
    • Data Source
      KAKENHI-PROJECT-15H04780
  • [Presentation] Defective binding of plectin and collagen XVII leads to epidermolysis bullosa simplex.2016

    • Author(s)
      Natsuga K, Nihsie W, Nishimura M, Shinkuma S, Watanabe M, Izumi K, Nakamura H, Hirako Y, Shimizu H
    • Organizer
      The 46th Annual European Society for Dermatological Research meeting.
    • Place of Presentation
      Technical University of Munich, Munich, Germany
    • Year and Date
      2016-09-07
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10120
  • [Presentation] 核内受容体の転写活性化を介した新規甲状腺ホルモンかく乱機構の解析2015

    • Author(s)
      清水良、渡部容子、浦丸直人、小島弘幸、武内伸治、黒木広明、太田茂、北村繁幸、杉原数美
    • Organizer
      フォーラム2015衛生薬学・環境トキシコロジー
    • Place of Presentation
      神戸学院大学ポートアイランドキャンパス (兵庫県・神戸市)
    • Year and Date
      2015-09-17
    • Data Source
      KAKENHI-PROJECT-15H04780
  • [Presentation] A single laminin subunit deficiency alters other laminin expression depending on the mutated genes.2015

    • Author(s)
      Natsuga K, Nishie W, Shinkuma S, Nakamura H, Watanabe M, Kambe M, Hatamochi A, Kimura U, Suga Y, Shimizu H
    • Organizer
      The 40th Annual Meeting of the Japanese Society for Investigative Dermatology
    • Place of Presentation
      Okayama convention center, Okayama, Okayama-City
    • Year and Date
      2015-12-11
    • Data Source
      KAKENHI-PROJECT-25461661
  • [Presentation] Generation of transgene-free induced pluripotent stem cells from keratinocytes of recessive dystrophic epidermolysis bullosa patients.2015

    • Author(s)
      Wakana Matsumura, Yasuyuki Fujita, Satoru Shinkuma, Inkin Ujiie, Takuma Matsumoto, Toshifumi Nomura, Riichiro Abe, Hiroshi Shimizu
    • Organizer
      The 40th Annual Meeting of the Japanese Society for Investigative Dermatology.
    • Place of Presentation
      岡山コンベンションセンター(岡山県岡山市)
    • Year and Date
      2015-12-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09753
  • [Presentation] Detection of pathological cleavage sites and neoepitopes on collagen XVII, a major autoantigen for bullous pemphigoid.2013

    • Author(s)
      Nishie W, Ujiie H, Izumi K, Shimizu H
    • Organizer
      The International Investigative Dermatology 2013
    • Place of Presentation
      Edinburgh, Scotland
    • Data Source
      KAKENHI-PROJECT-25670494
  • [Presentation] Bullous pemphigoid autoantibodies induce skin fragility in neonatal mice in a complement-independent manner.2013

    • Author(s)
      Sasaoka T, Ujiie H, Nishie W, Shibaki A, Nakamura H, Shimizu H
    • Organizer
      The 6th International Investigative Dermatology 2013
    • Place of Presentation
      Edinburgh International Conference Centre (イギリス)
    • Data Source
      KAKENHI-PROJECT-23591635
  • [Presentation] Detection of pathological cleavage sites and neoepitopes on collagen XVII, a major autoantigen for bullous pemphigoid2013

    • Author(s)
      Nishie W, Ujiie H, Izumi K, Shimizu H
    • Organizer
      The International Investigative Dermatology 2013
    • Place of Presentation
      Edinburgh International Conference Centre (UK)
    • Data Source
      KAKENHI-PROJECT-25670494
  • [Presentation] Bullous pemphigoid autoantibodies induce skin fragility in neonatal mice in a complementindependent manner.2013

    • Author(s)
      Sasaoka T, Ujiie H, Nishie W, Shibaki A, Nakamura H, Shimizu H
    • Organizer
      The International Investigative Dermatology
    • Place of Presentation
      Edinburgh International Conference Centre (Scotland)
    • Data Source
      KAKENHI-PROJECT-25461661
  • [Presentation] Bullous pemphigoid autoantibodies induce skin fragility in neonatal mice in a complement-independent manner2013

    • Author(s)
      Sasaoka T, Ujiie H, Nishie W, Shibaki A, Nakamura H, Shimizu H
    • Organizer
      The 6th International Investigative Dermatology 2013
    • Place of Presentation
      イギリス
    • Year and Date
      2013-05-09
    • Data Source
      KAKENHI-PROJECT-23591635
  • [Presentation] Essential role of collagen XVII in basement membrane formation and keratinocyte migration.2013

    • Author(s)
      Nishimura M, Nihsie W, Shinkuma S, Natsuga K, Nakamura H, Sawamura D, Iwatsuki K, Shimizu H
    • Organizer
      The International Investigative Dermatology
    • Place of Presentation
      Edinburgh International Conference Centre (Scotland)
    • Data Source
      KAKENHI-PROJECT-25461661
  • [Presentation] (特別講演)アトピー性皮膚炎とフィラグリン遺伝子変異2013

    • Author(s)
      清水宏
    • Organizer
      第7回くろしお皮膚談話会
    • Place of Presentation
      ホテル日航高知旭ロイヤル(高知市)
    • Data Source
      KAKENHI-PROJECT-24390152
  • [Presentation] AAGAB遺伝子変異を認めた点状掌蹠角化症の3家系2013

    • Author(s)
      乃村俊史,米田明弘,木花いづみ,末廣晃宏,秋山真志,W.H.Irwin McLean,清水宏
    • Organizer
      第28回角化症研究会
    • Place of Presentation
      東京商工会議所(東京都)
    • Data Source
      KAKENHI-PROJECT-24390152
  • [Presentation] アトピー性皮膚炎の最新の話題2012

    • Author(s)
      清水宏
    • Organizer
      苫小牧小児科医会学術講演会
    • Place of Presentation
      グランドホテルニュー王子(北海道)(特別講演)
    • Year and Date
      2012-10-30
    • Data Source
      KAKENHI-PROJECT-24390152
  • [Presentation] Monoclonal human IgG1 and IgG4 against COL17 induce skin fragility in neonatal COL17-humanized mice in a complement-independent manner.2012

    • Author(s)
      Sasaoka T, Ujiie H, Nishie W, Shibaki A, Shinkuma S, Tanabe M, Nakamura H, Shimizu H
    • Organizer
      The 37th Annual Meeting of the Japanese Society for Investigative Dermatology
    • Place of Presentation
      ロワジールホテル&スパタワー那覇(沖縄県)
    • Data Source
      KAKENHI-PROJECT-23591635
  • [Presentation] Monoclonal human IgG1 and IgG4 against COL17 induce skin fragility in neonatal COL17-humanized mice in a complement-independent manner2012

    • Author(s)
      Sasaoka T, Ujiie H, Nishie W, Shibaki A, Shinkuma S, Tanabe M, Nakamura H, Shimizu H
    • Organizer
      The 37th Annual Meeting of the Japanese Society for Investigative Dermatology
    • Place of Presentation
      沖縄県
    • Year and Date
      2012-12-07
    • Data Source
      KAKENHI-PROJECT-23591635
  • [Presentation] Long-term follow-up of cultured epidermal autograft in a recessive dystrophic epidermolysis bullosa patient2012

    • Author(s)
      Shinkuma S, Sawamura D, Kawasaki H, Nakamura H, Inoie M, Nishie W, Shimizu H
    • Organizer
      72nd Annual Meeting of the SOCIETY FOR INVESTIGATIVE DERMATOLOGY
    • Place of Presentation
      Raleigh Convention Center(米国)
    • Data Source
      KAKENHI-PROJECT-24659516
  • [Presentation] Therapeutic Strategies For TargetingAutoreactive T Cells In Autoimmune Bullous Diseases2011

    • Author(s)
      Ujiie H, Shibaki A, Moriuchi R, Shimizu H
    • Organizer
      22nd World Congress of Dermatology
    • Place of Presentation
      Soul, Korea
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] Novel Mouse Models of Human Skin Diseases2011

    • Author(s)
      Ujiie H, Nishie W, Fujita Y, ShibakiA, Shimizu H
    • Organizer
      22nd World Congress of Dermatology
    • Place of Presentation
      Soul, Korea
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] Exploring stem cell therapies for junctional epidermolysis bullosa model mice2011

    • Author(s)
      Fujita Y, Abe R, Nishie W, Shimizu H.
    • Organizer
      The 22nd World Congress of Dermatology
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2011-05-26
    • Data Source
      KAKENHI-PROJECT-23659539
  • [Presentation] 骨髄異形成症候群を合併した壊疽性膿皮症の1例2010

    • Author(s)
      松村若菜, 氏家英之, 泉健太郎, 秋山真志, 清水宏, 今野哲, 重松明男, 小野澤真弘
    • Organizer
      第381回日本皮膚科学会北海道地方会
    • Place of Presentation
      北海道大学学術交流会館札幌
    • Year and Date
      2010-02-06
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] アトピー性皮膚炎におけるフィラグリン遺伝子変異2010

    • Author(s)
      清水宏
    • Organizer
      第34回小児皮膚科学セミナー
    • Place of Presentation
      新宿野村ビル48階野村コンファレンスプラザ東京
    • Year and Date
      2010-03-20
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] Humanization of autoantigen to develop novel models of autoimmunity2010

    • Author(s)
      Shimizu H
    • Organizer
      37th Annual Meeting"Arbeitsgemeinschaft Dermato logische Forschung"
    • Place of Presentation
      Univestity of Lubeck, Lubeck, Germany
    • Year and Date
      2010-02-18
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] Yellow nail syndromeの1例2010

    • Author(s)
      林韻欣, 阿部理一郎, 柳輝希, 阿部由紀子, 眞木賀奈子, 清水宏
    • Organizer
      第381回日本皮膚科学会北海道地方会
    • Place of Presentation
      北海道大学学術交流会館札幌
    • Year and Date
      2010-02-06
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] アトピー性皮膚炎の予防・治療法の開発及び確立に関する研究2010

    • Author(s)
      清水宏, 戸倉新樹, 秋山真志, 有田賢
    • Organizer
      免疫アレルギ疾患等予防・治療研究事業研究報告会
    • Place of Presentation
      KKRホテル東京10階瑞宝の間東京
    • Year and Date
      2010-01-26
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] Active Mouse Model for Bullous Pemphigoid.2010

    • Author(s)
      Shimizu H
    • Organizer
      The 7th Annual Scientific Meeting Austral asian Society for Dermatology Research.
    • Place of Presentation
      Hilton Hotel Cairns, Cairns, Australia 招待講演
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] ペグインターフェロンfΩ-2bの局所注射にて皮膚潰瘍を生じた1例2010

    • Author(s)
      泉健太郎, 猪熊大輔, 松村若菜, 秦洋郎, 秋山真志, 清水宏, 西谷道子
    • Organizer
      第381回日本皮膚科学会北海道地方会
    • Place of Presentation
      北海道大学学術交流会館札幌
    • Year and Date
      2010-02-06
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] ステロイド外用にて早期に寛解した小児後天性表皮水疱症の1例2010

    • Author(s)
      林欣宇, 柳輝希, 飯谷麻里夏, 守内玲寧, 崎山幸雄, 清水宏
    • Organizer
      第381回日本皮膚科学会北海道地方会
    • Place of Presentation
      北海道大学学術交流会館札幌
    • Year and Date
      2010-02-06
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] Active Mouse Model for BullousPemphigoid2010

    • Author(s)
      Shimizu H
    • Organizer
      The 7^<th> Annual Scientific Meeting Australasian Society for Dermatology Research
    • Place of Presentation
      Australia
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] 角層下膿疱症(Subcorneal pustular dermatosis : SPD)の1例.2010

    • Author(s)
      水野修, 阿部理一郎, 新熊悟, 阿部由紀子, 清水宏
    • Organizer
      第381回日本皮膚科学会北海道地方会
    • Place of Presentation
      北海道大学学術交流会館札幌
    • Year and Date
      2010-02-06
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] 重篤な眼症状を伴った木村氏病の1例2010

    • Author(s)
      渡邉美佳, 氏家英之, 齊藤奈央, 柳輝希, 阿部理一郎, 清水宏
    • Organizer
      第381回日本皮膚科学会北海道地方会
    • Place of Presentation
      北海道大学学術交流会館札幌
    • Year and Date
      2010-02-06
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] アトピー性皮膚炎におけるフィラグリン遺伝子変異2010

    • Author(s)
      清水宏
    • Organizer
      日本皮膚科学会東北六県合同地方会学術大会第349回例会
    • Place of Presentation
      民陵会館2階「記念ホール」仙台
    • Year and Date
      2010-02-07
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] 眼部に生じた壊疽性膿皮症の2例2010

    • Author(s)
      齋藤奈央, 柳輝希, 林欣宇, 笠井聡美, 山根尚子, 猪熊大輔, 加瀬諭, 大野健太郎, 皆川英彦, 清水宏
    • Organizer
      第381回日本皮膚科学会北海道地方会
    • Place of Presentation
      北海道大学学術交流会館札幌
    • Year and Date
      2010-02-06
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] 胸肋関節から生じた皮膚腺病の一例2009

    • Author(s)
      松村若菜, 阿部理一郎, 泉健太郎, 保科大地, 阿部由紀子, 清水宏
    • Organizer
      第379回日本皮膚科学会北海道地方会
    • Place of Presentation
      大正富山医薬品(株)5階会議室札幌
    • Year and Date
      2009-10-03
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] ABCA subfamily member expression in the epidermis is altered by knockdown of ABCA122009

    • Author(s)
      Long H, Akiyama M, Yanagi T, Shimizu H
    • Organizer
      The 39th European Society for Dermatological Research(ESDR)Annual Meeting
    • Place of Presentation
      Semmelweis University, Budapest, Hungary
    • Year and Date
      2009-09-10
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] Wells症候群との鑑別を要したアレルギー性肉芽種性血管炎(AGA)の1例2009

    • Author(s)
      松村若菜, 藤田靖幸, 馬場慶子, 山根尚子, 芝木晃彦, 清水宏, 片岡浩
    • Organizer
      第380回日本皮膚科学会北海道地方会
    • Place of Presentation
      北海道大学学術交流会館札幌
    • Year and Date
      2009-12-12
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] Abca12. -|- harlequin ichthyosis model mouse shows alveolar collapse as well as severe fetal skin barrier defects2009

    • Author(s)
      Yanagi T, Akiyama M, Nishihara H, Sakai K, Nishie W, Tanaka S, Shimizu H
    • Organizer
      The 4th Joint Meeting of Japanese Dermatological Association and Australasian College of Dermatologists
    • Place of Presentation
      Hokkaido University, Sapporo, Japan
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] 血漿交換療法が著効した中毒性表皮壊死症の一例2009

    • Author(s)
      馬場慶子, 阿部理一郎, 飯谷麻里, 猪熊大輔, 三浦正義, 安藤佐土美, 松村和子, 清水宏
    • Organizer
      第39回日本皮膚アレルギー・接触皮膚炎学会総会学術大会
    • Place of Presentation
      国立京都国際会館京都
    • Year and Date
      2009-11-07
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] Bone marrow transplantation restores deficient epidermal basement membrane protein and improves the clinical phenotype in epidermolysis bullosa model mice2009

    • Author(s)
      Fujita Y, Abe R, Inokuma D, Sasaki M, Hoshina D, Nishie W, Natsuga K, McMilan J, Nakamura H, Shimizu H
    • Organizer
      The 4th Joint Meeting of Japanese Dermatological Association and Australasian College of Dermatologists
    • Place of Presentation
      Hokkaido University, Sapporo, Japan
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] Expression of ABCA subfamily member in the epidermis is affected by knockout of ABCA122009

    • Author(s)
      Long HA, Akiyama M, Yanagi T, Shimizu H
    • Organizer
      The 34th Annual Meeting of the Japanese Society for Investigative Dermatology
    • Place of Presentation
      JAL resort, Fukuoka, Japan
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] 北海道で発症したスポロトリコーシス2009

    • Author(s)
      猪熊大輔, 芝木晃彦, 清水宏, 芝木秀臣
    • Organizer
      第378回日本皮膚科学会北海道地方会
    • Place of Presentation
      旭川市大雪クリスタルホール旭川
    • Year and Date
      2009-06-14
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] Kindler症候群の日本人症例2009

    • Author(s)
      夏賀健, 西江渉, 新熊悟, 中村秀樹, 長崎暁理, 清水宏, 立田彩, 小宮根真弓, 松島陽一郎
    • Organizer
      第31回水疱症研究会
    • Place of Presentation
      大和屋本店・愛媛県医師会館松山
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] Collagen XVII in hemidesmosomes is involved in keratinocyte-collagen IV adhesion and p38-MAPK-dependent cell migration and signaling2009

    • Author(s)
      McMillan J, Qiao H, Shibaki A, Long H, Wang G, Nishie W, Akiyama M, Shimizu H
    • Organizer
      The 39th European Society for Dermatological Research(ESDR)Annual Meeting
    • Place of Presentation
      Semmelweis University, Budapest, Hungary
    • Year and Date
      2009-09-10
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] 基底細胞癌に対するdouble bladed scalpelを用いたmicrographic surgeryの経験2009

    • Author(s)
      青柳哲, 秦洋郎, 泉建太郎, 清水宏
    • Organizer
      第25回日本皮膚悪性種瘍学会学術大会
    • Place of Presentation
      岡山コンベンションセンター岡山
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] Novel mutation of FLG, p.Lys4021X in the C-terminal imperfect filaggrin repeat in Japanese atopic dermatitis patients2009

    • Author(s)
      Nemoto-Hasebe I, Akiyama M, Nomura T, Sandilands A, McLean W, Shimizu H
    • Organizer
      The 34th Annual Meeting of the Japanese Society for Investigative Dermatology
    • Place of Presentation
      JAL resort, Fukuoka, Japan
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] Genetic variation of DSG3 is associated with pemphigus vulgaris among Japanese2009

    • Author(s)
      Niizeki H, Asada H, Amagai M, Oka A, Inoko H, Hashimoto T, Ikeda S, Shimizu H, Kitajima Y, Miyagawa S, Yamamoto S, Aoyama Y, Ichiki Y, Shimizu T, Takahashi H, Kuwana M, Shirakata Y, Hashimoto K, Yamamoto T, Iwatsuki K, Inaoki M, Fujimoto W, Nakamura K, Kishimoto K, Kaneko F, Kunii T, Aiba S, Terui T
    • Organizer
      The 34th Annual Meeting of the Japanese Society for Investigative Dermatology
    • Place of Presentation
      JAL resort, Fukuoka, Japan
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] 道化師様魚鱗癬モデルマウスは、肺胞拡張不全と重篤な皮膚バリア障害を来す2009

    • Author(s)
      柳輝希, 秋山真志, 西原広史, 坂井香織, 西江渉, 田中仲哉, 清水宏
    • Organizer
      第108回日本皮膚科学会総会
    • Place of Presentation
      福岡国際会議場、マリンメッセ福岡福岡
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] 重篤な後遺症を残した成人麻疹脳炎の1例2009

    • Author(s)
      飯谷麻里, 伊藤圭, 和田剛志, 澤村淳, 清水宏
    • Organizer
      第60回日本皮膚科学会中部支部学術大会
    • Place of Presentation
      国立京都国際会館京都
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] Development of a rapid immunochromatographic test for the detection of high-level serum ranulysin in an early stage of SJS and TEN2009

    • Author(s)
      Abe R, Yoshioka N, Murata J, Fujita Y, Hoshina D, Mae H, Shimizu H
    • Organizer
      The 34th Annual Meeting of the Japanese Society for Investigative Dermatology
    • Place of Presentation
      JAL resort, Fukuoka, Japan
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] Collagen XVII participates in keratinocyte adhesion to collagen IV, and in p38-MAPK-dependent migration and cell signaling2009

    • Author(s)
      Qiao H, Shibaki A, Long H, Wang G, Li Q, Nishie W, Abe R, Akiyama M, Shimizu H, McMillan J
    • Organizer
      the 69th Society for Investigative Dermatology Annual Meeting
    • Place of Presentation
      Palais des congres Montreal, Canada
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] Gemcitabineにより強皮症様皮疹を呈した一例2009

    • Author(s)
      笠井聡美, 阿部理一郎, 泉健太郎, 藤田靖幸, 阿部由紀子, 清水宏, 桑名将城, 河上洋
    • Organizer
      第73回日本皮膚科学会東部支部学術大会
    • Place of Presentation
      甲府富土屋ホテル山梨
    • Year and Date
      2009-09-27
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] (JSID Symposium)Atopic dermatitis : Its skin barrier function and filaggrin mutations2009

    • Author(s)
      Shimizu H
    • Organizer
      The 18th Congress of the European Academy of Dermatology and Venereology
    • Place of Presentation
      The Internationales Congress Centrum Berlin, Berlin, Germany
    • Year and Date
      2009-10-07
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] Establishment of a novel experimental model of human angiosarcoma2009

    • Author(s)
      Hoshina D, Abe R, Hata H, Fujita Y, Yoshioka N, Aoyagi T, Shimizu H
    • Organizer
      The 34th Annual Meeting of the Japanese Society for Investigative Dermatology
    • Place of Presentation
      JAL resort, Fukuoka, Japan
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] 表皮水疱症の新しい治療法"骨髄移植"2009

    • Author(s)
      清水宏
    • Organizer
      第73回日本皮膚科学会東部支部学術大会
    • Place of Presentation
      甲府富士屋ホテル山梨
    • Year and Date
      2009-09-27
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] Plectin expression in epidermolysis bullosa simplex(EBS)with muscular dystrophy vs.in EBS with pyloric atresia2009

    • Author(s)
      Natsuga K, Nishie W, Akiyama M, Ouchi T, Ishiko A, Hirako Y, Owaribe K, Buckner-Tuderman L, Shimizu H
    • Organizer
      The 39th European Society for Dermatological Research(ESDR)Annual Meeting
    • Place of Presentation
      Semmelweis University, Budapest, Hungary
    • Year and Date
      2009-09-10
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] Development of an active bullous pemphigoid mouse model2009

    • Author(s)
      Ujiie H, Shibaki A, Nishie W, Sawamura D, Wang G, Tateishi Y, Li Q, Nakamura H, Akiyama M, Shimizu H
    • Organizer
      The 4th Joint Meeting of Japanese Dermatological Association and Australasian College of Dermatologists
    • Place of Presentation
      Hokkaido University, Sapporo, Japan
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] Transdifferentiation of bone marrow stem cells into keratinocytes2009

    • Author(s)
      Shimizu H
    • Organizer
      EB 2009
    • Place of Presentation
      Mariott Hotel, Vienna, Austria
    • Year and Date
      2009-09-07
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] タクロリム軟膏外用が奏効した爪扁平苔癬5例のまとめ2009

    • Author(s)
      氏家英之, 芝木晃彦, 秋山真志, 清水宏
    • Organizer
      第73回日本皮膚科学会東部支部学術大会
    • Place of Presentation
      甲府富土屋ホテル山梨
    • Year and Date
      2009-09-27
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] 血清granulysin値は重症薬疹の発症早期に上昇する2009

    • Author(s)
      吉岡直也, 阿部理一郎, 村田純子, 藤田靖幸, 清水宏
    • Organizer
      第21回日本アレルギー学会春季臨床大会
    • Place of Presentation
      長良川国際会議場岐阜
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] (Plenary Lecture)"Mouse models of human diseases"2009

    • Author(s)
      Shimizu H
    • Organizer
      The 18th Annual Meeting of the European Academy of Dermatology and Venereology
    • Place of Presentation
      The Internationales Congress Centrum Berlin, Berlin, Germany
    • Year and Date
      2009-10-08
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] 筋ジストロフィー合併単純型表皮水疱症におけるプレクチン発現パターンの解析2009

    • Author(s)
      清水宏, 夏賀健, 西江渉
    • Organizer
      稀少難治性皮膚疾患に関する調査研究班 平成21年度第1回総会
    • Place of Presentation
      KKRホテル東京11階丹頂の間東京
    • Year and Date
      2009-07-24
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] 表在播種型汗孔角化症に有棘細胞癌およびBowen病を生じた1例2009

    • Author(s)
      山根尚子, 青柳哲, 馬慶場子, 秦洋郎, 清水宏, 菊池敏郎
    • Organizer
      第25回日本皮膚悪性腫瘍学会学術大会
    • Place of Presentation
      岡山コンベンションセンター岡山
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] アトピー性皮膚炎患者におけるフィラグリン遺伝子変異2009

    • Author(s)
      清水宏
    • Organizer
      第39回日本皮膚アレルギー・接触皮膚炎学会総会学術大会
    • Place of Presentation
      国立京都国際会館京都
    • Year and Date
      2009-11-07
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] Stem cell transplantation treatment restores deficient type XVII collagen in junctional epidermolysis bullosa model mice2009

    • Author(s)
      Fujita Y, Abe R, Inokuma D, Sasaki M, Natsuga K, Nishie W, Nakamura H, Akiyama M, Sawamura D, Shimizu H
    • Organizer
      The 34th Annual Meeting of the Japanese Society for Investigative Dermatology
    • Place of Presentation
      JAL resort, Fukuoka, Japan
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] Humanization of autoantigen:水疱性類天疱瘡の病態解明と新規治療法開発2009

    • Author(s)
      清水宏
    • Organizer
      第37回日本臨床免疫学会総会
    • Place of Presentation
      東京ステーションコンファレンス東京
    • Year and Date
      2009-11-14
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] (Symposium)Harlequin Ichthyosis and Lamellar Ichthyosis : Molecular Diagnosis and Prenatal Diagnosis2009

    • Author(s)
      Shimizu H
    • Organizer
      11th World Congress of Pediatric Dermatology
    • Place of Presentation
      Queen Sirikit National Convention Center, Bangkok, Thailand
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] 腹部に生じた血管肉腫の1例2009

    • Author(s)
      本間英里奈, 青柳哲, 笠井聡美, 松村若菜, 渡邉美佳, 馬場慶子, 飯谷麻里, 秦洋郎, 藤田靖幸, 清水宏
    • Organizer
      第380回日本皮膚科学会北海道地方会
    • Place of Presentation
      北海道大学学術交流会館札幌
    • Year and Date
      2009-12-12
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] 亜鉛による歯科金属アレルギーの1例2009

    • Author(s)
      齋藤奈央, 山根尚子, 松村若菜, 藤田靖幸, 猪熊大輔, 黒嶋伸一郎, 浜坂幸吉, 清水宏
    • Organizer
      第39回日本皮膚アレルギー・接触皮膚炎学会総会学術大会
    • Place of Presentation
      国立京都国際会館京都
    • Year and Date
      2009-11-07
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] Both hematopoietic and mesenchymal stem cells contribute to the production of basement membrane protein in bone marrow transplantation treatment model mouse2009

    • Author(s)
      Fujita Y, Abe R, Inokuma D, Nishie W, Nakamura H, Akiyama M, Sawamura D, Shimizu H
    • Organizer
      The 39th European Society for Dermatological Research(ESDR)Annual Meeting
    • Place of Presentation
      Semmelweis University, Budapest, Hungary
    • Year and Date
      2009-09-10
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] 道化師様魚鱗癬の1例2009

    • Author(s)
      高野優佳子, 後藤瑞生, 甲斐宜貴, 片桐一元, 藤原作平, 関口和人, 泉達郎, 山田喜三郎, 中塚和夫, 秋山真志, 清水宏
    • Organizer
      第108回日本皮膚科学会総会
    • Place of Presentation
      福岡国際会議場、マリンメッセ福岡福岡
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] 水疱性類天疱瘡:up-date2009

    • Author(s)
      清水宏
    • Organizer
      第1回関西皮膚自己免疫疾患談話会
    • Place of Presentation
      大阪リーガロイヤルホテルタワーウイング2階「桐の間」大阪
    • Year and Date
      2009-06-12
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] 水疱性類天疱瘡の病態解明と新規治療法の開発2009

    • Author(s)
      清水宏
    • Organizer
      第46回日本臨床分子医学会学術集会
    • Place of Presentation
      東京国際フォーラム東京
    • Year and Date
      2009-04-13
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] 幽門閉鎖合併単純型表皮水疱症におけるプレクチン発現パターンの解析2009

    • Author(s)
      清水宏, 夏賀健, 西江渉
    • Organizer
      稀少難治性皮膚疾患に関する調査研究班 平成21年度第2回総会
    • Place of Presentation
      KKRホテル東京11階丹頂の間東京
    • Year and Date
      2009-12-18
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] フィラグリン遺伝子変異関連アトピー性皮膚炎では、臨床重症度とバリア障害重証度は相関する2009

    • Author(s)
      長谷部育恵, 秋山真志, 乃村後史, Sandilands A, Mclean I, 清水宏
    • Organizer
      第108回日本皮膚科学会総会
    • Place of Presentation
      福岡国際会議場、マリンメッセ福岡福岡
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] Presence of plectin rodless isoform is a key predictor of phenotypic severity in plectin deficient epidermolysis bullosa simpex2009

    • Author(s)
      Natsuga K, Nishie W, Akiyama M, Shinkuma S, Nakamura H, McMillan JR, Nagasaki A, Has C, Ouchi T, Ishiko A, Hirako Y, Owaribe K, Sawamura D, Leena B-T, Shimizu H
    • Organizer
      The 34th Annual Meeting of the Japanese Society for Investigative Dermatology
    • Place of Presentation
      JAL resort, Fukuoka, Japan
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] 周囲への浸潤傾向を示した顆粒細胞腫の1例2009

    • Author(s)
      洪綺憶, 青柳哲, 本間英里奈, 西村真智子, 笠井麻希, 秦洋郎, 松村和子, 清水宏
    • Organizer
      第73回日本皮膚科学会東部支部学術大会
    • Place of Presentation
      甲府富土屋ホテル山梨
    • Year and Date
      2009-09-27
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] 皮下型平滑筋肉腫の1例2009

    • Author(s)
      馬場慶子, 青柳哲, 西村真智子, 秦洋郎, 清水宏, 松村和子
    • Organizer
      第380回日本皮膚科学会北海道地方会
    • Place of Presentation
      北海道大学学術交流会館札幌
    • Year and Date
      2009-12-12
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] プレクチンの発現様式の違いによって2種類の表皮水疱症の臨床型が決定される2009

    • Author(s)
      夏賀健, 西江渉, 秋山真志, 新熊悟, 中村秀樹, 長崎暁理, Has C, 大内健嗣, 石河晃, 平子義章, 尾張部克志, 澤村大輔, Leena B-T, 清水宏
    • Organizer
      第379回日本皮膚科学会北海道地方会
    • Place of Presentation
      大正富山医薬品(株)5階会議室札幌
    • Year and Date
      2009-10-03
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] 筋肉内浸潤および脾梗塞を呈した進行期菌状息肉症の1例2009

    • Author(s)
      渡邉美佳, 氏家英之, 馬場慶子, 阿部理一郎, 芝木晃彦, 山田洋介, 山口圭介, 神山俊哉, 清水宏
    • Organizer
      第380回日本皮膚科学会北海道地方会
    • Place of Presentation
      北海道大学学術交流会館札幌
    • Year and Date
      2009-12-12
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] フィラグリン遺伝子変異を有するアミロイド苔癬2009

    • Author(s)
      野村友希子, 秋山真志, 長谷部育恵, 剱持靖子, 乃村俊史, 清水宏
    • Organizer
      第36回皮膚かたち研究学会学術大会
    • Place of Presentation
      宮崎県医師会館宮崎
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] 11歳男児にみられた乳腺嚢胞の1例2009

    • Author(s)
      林韻欣, 青柳哲, 齋藤奈央, 秦洋郎, 芝木晃彦, 清水宏
    • Organizer
      第379回日本皮膚科学会北海道地方会
    • Place of Presentation
      大正富山医薬品(株)5階会議室札幌
    • Year and Date
      2009-10-03
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] 塊状のIgA沈着を呈したDuhring疱疹状皮膚炎の1例2009

    • Author(s)
      林欣宇, 氏家英之, 渡邉美佳, 馬場慶子, 新熊悟, 阿部理一郎, 清水宏
    • Organizer
      第380回日本皮膚科学会北海道地方会
    • Place of Presentation
      北海道大学学術交流会館札幌
    • Year and Date
      2009-12-12
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] 播種性血管内凝固症候群を合併したStevens-Johnson syndromeの1例2009

    • Author(s)
      野村友希子, 阿部理一郎, 太田光, 馬場慶子, 秦洋郎, 山根尚子, 清水宏
    • Organizer
      第378回日本皮膚科学会北海道地方会
    • Place of Presentation
      旭川市大雪クリスタルホール旭川
    • Year and Date
      2009-06-14
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] Hemidesmosomal collagen XVII enhances keratinocyte adhesion to collagen IV, and in p38-MAPK-dependent migration and cell signaling2009

    • Author(s)
      McMillan J, Qiao H, Shibaki A, Long H, Wang G, Li Q, Nishie W, Abe R, Akiyama M, Shimizu H
    • Organizer
      6th Annual Scientific Meeting Australasian Society for Dermatology Research
    • Place of Presentation
      Courtyard by Marriott Surfers Paradise, QLD, Australia
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] 発熱を伴った紅斑、丘疹2009

    • Author(s)
      飯谷麻里, 小玉和郎, 馬場慶子, 野村友希子, 川崎浩之, 山中快子, 阿部由紀子, 阿部理一郎, 清水宏
    • Organizer
      第25回皮膚病理組織学会
    • Place of Presentation
      石垣記念ホール東京
    • Year and Date
      2009-07-29
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] Genotoxic Stress Induces Hair Graying Through Melanocyte Stem Cell Differentiation in the niche2009

    • Author(s)
      Inomata K, Aoto T, Binh NT, Okamoto N, Tanimura S, Wakayama T, Iseki S, Hara E, Masunaga T, Shimizu H, Nishimura EK
    • Organizer
      The 34th Annual Meeting of the Japanese Society for Investigative Dermatology
    • Place of Presentation
      JAL resort, Fukuoka, Japan
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] A case of disseminated intravascular coagulation associated with Stevens-Johnson syndrome2009

    • Author(s)
      Nomura Y, Abe R, Ota H, Baba K, Hata H, Yamane N, Shimizu H
    • Organizer
      The 4th Joint Meeting of Japanese Dermatological Association and Australasian College of Dermatologists
    • Place of Presentation
      Hokkaido University, Sapporo, Japan
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] OSMR遣伝子変異を確認しえた日本人家族性皮膚限局性アミロイドーシスの1例2009

    • Author(s)
      有田賢, 阿部理一郎, 馬場慶子, 秋山真志, 清水宏
    • Organizer
      第108回日本皮膚科学会総会
    • Place of Presentation
      福岡国際会議場、マリンメッセ福岡福岡
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] 汎発性膿疱性乾癬に進展したPsoriatic onycho-pachydermo periostitis(POPP)の1例2009

    • Author(s)
      渡遷美佳, 氏家英之, 飯谷麻里, 阿部理一郎, 清水宏
    • Organizer
      第73回日本皮膚科学会東部支部学術大会
    • Place of Presentation
      甲府富土屋ホテル山梨
    • Year and Date
      2009-09-27
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] 皮膚結節性アミロイドーシスの2例2009

    • Author(s)
      泉健太郎, 猪熊大輔, 笠井麻希, 藤田靖幸, 氏家英之, 山中快子, 伊藤圭, 清水宏
    • Organizer
      第108回日本皮膚科学会総会
    • Place of Presentation
      福岡国際会議場、マリンメッセ福岡福岡
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] ヒト血管肉腫実験モデルを用いた抗ヒトVEGF抗体(bevacizumab)の抗腫瘍効果の検討2009

    • Author(s)
      保科大地, 阿部理一郎, 秦洋郎, 藤田靖幸, 青柳哲, 清水宏
    • Organizer
      第16回分子皮膚科学フォーラム
    • Place of Presentation
      札幌グランドホテル札幌
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] 頭皮円形欠損部に対する簡便な局所皮弁による再建例2009

    • Author(s)
      青柳哲, 本間英里奈, 秦洋郎, 清水宏
    • Organizer
      第24回日本皮膚外科学会・学術大会
    • Place of Presentation
      名鉄犬山ホテル愛知
    • Year and Date
      2009-06-21
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] フィラグリン遺伝子変異による皮膚バリア機能障害は、アトピー性皮膚炎の重要な発症因子である2009

    • Author(s)
      清水宏
    • Organizer
      第61回日本皮膚科学会西部支部学術大会
    • Place of Presentation
      別府国際コンベンションセンター大分
    • Year and Date
      2009-10-25
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] 北海道で発症したスポロトリコーシス2009

    • Author(s)
      猪熊大輔, 芝木晃彦, 清水宏, 芝木秀臣
    • Organizer
      第61回日本皮膚科学会西部支部学術大会
    • Place of Presentation
      別府国際コンベンションセンター大分
    • Year and Date
      2009-10-25
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] (Symposium)Lessons from a Novel Mouse Model for Epidermolysis Bullosa2009

    • Author(s)
      Shimizu H
    • Organizer
      11th World Congress of Pediatric Dermatology
    • Place of Presentation
      Queen Sirikit National Convention Center, Bangkok, Thailand
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] Novel animal models for skin diseases : Message from Sapporo2009

    • Author(s)
      Shimizu H
    • Organizer
      ADA 129th Annual Meeting
    • Place of Presentation
      Park City, Htah, U.S.A
    • Year and Date
      2009-08-22
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] 第2期梅毒の1例2009

    • Author(s)
      林韻欣, 藤田靖幸, 有田賢, 清水宏
    • Organizer
      第380回日本皮膚科学会北海道地方会
    • Place of Presentation
      北海道大学学術交流会館札幌
    • Year and Date
      2009-12-12
    • Data Source
      KAKENHI-PROJECT-21249063
  • [Presentation] Humanization of autoantigen2008

    • Author(s)
      Shimizu H
    • Organizer
      The 14th Chinese annual congress of dermatology
    • Place of Presentation
      Shanghai, China, Nanjing International exhibition center
    • Year and Date
      2008-06-13
    • Data Source
      KAKENHI-PROJECT-19044001
  • [Presentation] 正常ヒトXVII型コラーゲン遺伝子導入レスキューマウスの解析2008

    • Author(s)
      中村秀樹・西江渉・清水宏
    • Organizer
      平成20年度日本顕微鏡学会
    • Place of Presentation
      北海道大学歯学部講堂
    • Year and Date
      2008-12-13
    • Data Source
      KAKENHI-PROJECT-19591291
  • [Presentation] 骨髄移植は17型コラーゲンノックアウトマウスにおいて欠損蛋白を補充し生命予後を改善する2008

    • Author(s)
      藤田靖幸、中村秀樹、清水宏
    • Organizer
      第40回日本結合組織学会・第55回マトリックス研究学会合同学術集会
    • Place of Presentation
      東京
    • Year and Date
      2008-05-30
    • Data Source
      KAKENHI-PROJECT-19591291
  • [Presentation] 正常ヒトXVII型コラーゲン遺伝子導入レスキューマウスの解析2008

    • Author(s)
      中村秀樹、西江渉、清水宏
    • Organizer
      平成20年度日本顕微鏡学会
    • Place of Presentation
      札幌
    • Year and Date
      2008-12-13
    • Data Source
      KAKENHI-PROJECT-19591291
  • [Presentation] 骨髄移植は17型コラーゲンノックアウトマウスにおいて欠損タンパク補充し、生命予後を改善する2008

    • Author(s)
      藤田靖幸・中村秀樹・清水宏
    • Organizer
      第40回日本結合組織学会・第55回マトリックス研究学会合同学術集会
    • Place of Presentation
      東京こまばエミナース
    • Year and Date
      2008-05-30
    • Data Source
      KAKENHI-PROJECT-19591291
  • [Presentation] Humanization of autoantigen2008

    • Author(s)
      Shimizu H
    • Organizer
      The 14th Chinese annual congress of dermatology
    • Place of Presentation
      Nanjing International exhibition center, China
    • Year and Date
      2008-06-13
    • Data Source
      KAKENHI-PROJECT-20013002
  • [Presentation] Symposium "New technologies - Impact on dignosis and treatment" New animal model for bullous pemphigoid.2007

    • Author(s)
      Shimizu, H
    • Organizer
      The 21st World Congress of Dermatology
    • Place of Presentation
      Buenos Aires
    • Year and Date
      2007-10-05
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17209038
  • [Presentation] Symposium "New technologies - Impact on diagnosis and treatment" New animal model for bullous pemphigoid.2007

    • Author(s)
      Shimizu H
    • Organizer
      The 21st World Congress of Dermatology
    • Place of Presentation
      Buenos Aires
    • Year and Date
      2007-10-05
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17209038
  • [Presentation] Workshop "Epidermolysis bullosa" Cancer and wound healing.2007

    • Author(s)
      Shimizu H
    • Organizer
      The 21st World Congress of Dermatology
    • Place of Presentation
      La Rural Convention Center, Buenos Aires
    • Year and Date
      2007-10-02
    • Data Source
      KAKENHI-PROJECT-19044001
  • [Presentation] Novel mouse model for junctional epidermolysis bullosa2007

    • Author(s)
      Shimizu H.
    • Organizer
      The 21st World Congress of Dermatology
    • Place of Presentation
      Buenos Aires
    • Year and Date
      2007-10-05
    • Data Source
      KAKENHI-PROJECT-19591291
  • [Presentation] Workshop "Epidermolysis bullosa" Cancer and wound healing.2007

    • Author(s)
      Shimizu H
    • Organizer
      The 21st World Congress of Dermatology
    • Place of Presentation
      La Rural Convention Center, Buenos Aires
    • Year and Date
      2007-10-02
    • Data Source
      KAKENHI-PROJECT-18013002
  • [Presentation] Workshop "Epidermolysis bullosa"Cancer and wound healing.2007

    • Author(s)
      Shimizu H
    • Organizer
      The 21st World Congress of Dermatology
    • Place of Presentation
      La Rural Convention Center, Buenos Aires
    • Year and Date
      2007-10-02
    • Data Source
      KAKENHI-PROJECT-19659279
  • [Presentation] Novel mouse model for junctional epidermolysis bullosa2007

    • Author(s)
      Shimizu H
    • Organizer
      The 21st World Congress of Dermatology
    • Place of Presentation
      La Rural Convention Centre, Buenos Aires, Argentina
    • Year and Date
      2007-10-05
    • Data Source
      KAKENHI-PROJECT-19591291
  • [Presentation] Symposium "New technologies-Impact on diagnosis and treatment" New animal model for bullous pemphigoid e.2007

    • Author(s)
      Shimizu H
    • Organizer
      The 21st World Congress of Dermatology
    • Place of Presentation
      La Rural Convention Center, Buenos Aires
    • Year and Date
      2007-10-05
    • Data Source
      KAKENHI-PROJECT-17209038
  • [Presentation] RNA recognition motif of LEMD3 as a key player in the pathogenesis of Buschke-Ollendorff syndrome.

    • Author(s)
      Takashima S, Fujita Y, Suzuki S, Saito N, Shinkuma S, Nomura T, Shimizu H.
    • Organizer
      The 71st Annual Meeting of the Society for Investigative Dermatology
    • Place of Presentation
      Atlanta, US
    • Year and Date
      2015-05-06 – 2015-05-09
    • Data Source
      KAKENHI-PROJECT-24249062
  • [Presentation] Context-dependent tight regulation of collagen XVII ectodomain shedding in skin.

    • Author(s)
      Nihsie W, Natsuga K, Izumi K, Hata H, Nakamura H, Shimizu H
    • Organizer
      The 39th Annual Meeting of the Japanese Society for Investigative Dermatology
    • Place of Presentation
      Hotel Hankyu Expo Park, Osaka, Suita-City
    • Year and Date
      2014-12-12 – 2014-12-14
    • Data Source
      KAKENHI-PROJECT-25461661
  • [Presentation] Highly prevalent SERPINB7 founder mutation causes pseudodominant inheritance pattern in Nagashima-type palmoplantar keratosis.

    • Author(s)
      Mizuno O, Nomura T, Suzuki S, Takeda M, Ohguchi Y, Fujita Y, Nishie W, Sugiura K, Akiyama M, Shimizu H
    • Organizer
      The 44th European Society for Dermatological Research (ESDR) Annual Meeting
    • Place of Presentation
      Copenhagen, Denmark
    • Year and Date
      2014-09-10 – 2014-09-13
    • Data Source
      KAKENHI-PROJECT-24249062
  • [Presentation] One amino acid deletion in collagen XVII-binding domain of plectin with a truncation mutation underlies epidermolysis bullosa simplex.

    • Author(s)
      Natsuga K, Nishimura M, Nakamura H, Nihsie W, Shimizu H
    • Organizer
      The 39th Annual Meeting of the Japanese Society for Investigative Dermatology
    • Place of Presentation
      Hotel Hankyu Expo Park, Osaka, Suita-City
    • Year and Date
      2014-12-12 – 2014-12-14
    • Data Source
      KAKENHI-PROJECT-25461661
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  • 102.  藤田 春美
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 103.  小布施 力史
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 104.  山下 利春
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 105.  河野 通浩
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 106.  木原 章雄
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 107.  佐々 貴之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 108.  田口 良
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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