TAKEUCH Koji 竹内孝治

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TAKEUCHI Koji 竹内孝治

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Researcher Number	00150798
Other IDs
Affiliation (based on the past Project Information) *help	2006 – 2010: 京都薬科大学, 薬学部, 教授 2003: Kyoto Pharmaceutical University, Pharmacology and Experimental Therapeutics, Professor, 薬学部・薬物治療学教室, 教授 2003: 京都薬科大学, 薬物治療学教室, 教授 1996 – 2002: 京都薬科大学, 薬学部, 教授 1995: 京都薬科大学, 薬学部・薬物治療学, 教授 … More 1994: 京都薬科大学, 薬学部・応用薬理学, 助教授 1989 – 1993: 京都薬科大学, 薬学部, 助教授 1988: Department of Applied Pharmacology, 応用薬理学教室, 助教授 1987: 京都薬科大学, 薬学部, 助教授 Less
Review Section/Research Field	Principal Investigator 応用薬理学・医療系薬学 / General pharmacology Except Principal Investigator Applied pharmacology
Keywords	Principal Investigator 適応性反応 / 胃粘膜 / アルカリ分泌 / 知覚神経 / ヒスタミン / 酸分泌抑制 / 傷害発生 / 胃・十二指腸アルカリ分泌 / nitric oxide / 胃粘膜保護作用 … More / 粘膜血流 / 胃粘膜損傷 / cGMP / histamine / acid secretion / プロスタグランジン / 一酸化窒素 / 炭酸脱水酵素 / 炭酸水 / 輸送担体 / ホスホジエステラーゼ / 内因性メディエーター / 十二指腸アルカリ分泌 / 内因性一酸化窒素 / 胃粘膜血流 / カプサイシン感受性知覚神経 / カプサイシン / 内因性プロスタグランジン / 血管透過性 / インドメタシン / homeostasis of the gastric mucosa / endogenous prostaglandins / H_2-receptors / alkaline secretion / mucosal protection / 粘膜保護 / H_2-受容体 / 酸分泌 / 炎症 / 粘膜恒常性 / 防御機構 / 胃運動 / 粘膜保護作用 / carbonic anhydrease / carbonated beverages / phosphodiesterase isozyme / sensory nerve / transport / endogeneous mediator / gastroduodenal HCO_3^- secretion / 輪送担体 / cytoprotection / RGM1 / bicarbonate secretion / EP receptor subtype / gastric protection / vanilloid receptor type 1 / capsaicin / Capsaicin-sensitive afferent neuron / IP受容体 / EP / バニロイド受容体 / protection / microsphere capsule / colonic delivery / ulcerative colitis / ellagic acid / polyphenol / 抗酸化作用 / モノクロラミン胃損傷 / 炎症性病変 / 保護効果 / 圧感応性カプセル / 大腸デリバリー / 潰瘍性大腸炎 / エラグ酸 / ポリフェノール / small intestinal lesion / gastric lesion / indomethacin / USAIDs / 損傷治癒 / 胃粘膜傷害性 / NO遊離型アスピリン / 小腸損傷 / 胃損傷 / 関節炎モデル / 非ステロイド系抗炎症薬 / capsaicin-sensitive sensory neuron / mucosal mast cell / luminal Ca^<2+> / stomach / surface epithelial damage / 修復機転 / 管腔内Ca / 酸分泌変化 / ムスカリン(M)受容体サブタイプ / カルバコール / D細胞/ソマトスタチン / M受容体ノックアウトマウス / ソマトスタチン / D細胞 / M受容体ノックアウトマウト / ムスカリン受容体サブタイプ / コリン作動薬(カルバコール) / 一酸化炭素(CO) / 硫化水素(H_2S) / ガス状メディエーター / 酸分泌促進 / 胃酸分泌 / NO合成酵素阻害薬 L-NAME / 内皮由来弛緩因子 / 酸の逆拡散 / 治癒機転 / 胃・十二指腸 / 粘膜電位差 / ムスカリンM_2受容体 / コリン作動薬 / 測定方法 / 十二指腸 / 血糖 / 虚血-再灌流 / 胃運動亢進 … More Except Principal Investigator 一酸化窒素 / 小腸傷害 / プロスタグランジン / 胃潰瘍 / 胃粘膜傷害 / COX-2 / COX-1 / NSAIDs Less

Local regulatory mechanisms of gastroduodenal bicarbonate secretion :Principal Investigator
- Principal Investigator
  
  TAKEUCH Koji
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Kyoto Pharmaceutical University
Signalling pathways and transporters involved in gastroduodenal bicarbonate secretionPrincipal Investigator
- Principal Investigator
  
  TAKEUCHI Koji
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Kyoto Pharmaceutical University
非ステロイド系抗炎症薬(NSAIDs)による胃腸傷害の発生とCOX阻害との関連性-COX-1阻害により誘導されるCOX-2の役割と誘導機序-
- Principal Investigator
  
  TANAKA Akiko
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  Kyoto Pharmaceutical University
Distribution of vanilloid receptors (VR1) in gastrointestinal tract and their role in mucosal protection mediated by capsaicin-sensitive afferent neuronsPrincipal Investigator
- Principal Investigator
  
  TAKEUCHI Koji
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyoto Pharmaceutical University
Protection against dextran sulfate sodium-induced colitis by microsheres of polyphenol (ellagic acid)Principal Investigator
- Principal Investigator
  
  TAKEUCHI Koji
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for University and Society Collaboration
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyoto Pharmaceutical University
Development of NSAIDs that spare gastrointestinal tract injury.-COX-2 selective and NO-releasing NSAIDs-Principal Investigator
- Principal Investigator
  
  TAKEUCHI Koji
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyoto Pharmaceutical University
Regulatory mechanism of acid secretory response in the stomach following injury : Role of nitric oxide.Principal Investigator
- Principal Investigator
  
  TAKEUCHI Koji
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyoto Pharmaceutical University
傷害胃粘膜における胃酸分泌変化とその調節機構に関する研究:Nitric Oxideの役割Principal Investigator
- Principal Investigator
  
  竹内孝治
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyoto Pharmaceutical University
傷害胃粘膜における胃酸分泌変化とその調節機構に関する研究Principal Investigator
- Principal Investigator
  
  竹内孝治
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyoto Pharmaceutical University
胃粘膜の適応性反応における内皮由来血管弛緩因子(Nitric Oxide)の役割Principal Investigator
- Principal Investigator
  
  竹内孝治
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyoto Pharmaceutical University
カプサイシン感受性知覚神経を介する胃粘膜血流調節の生理学的意義に関する研究Principal Investigator
- Principal Investigator
  
  竹内孝治
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyoto Pharmaceutical University
胃・十二指腸の適応性反応におけるカプサイシン感受性神経の役割Principal Investigator
- Principal Investigator
  
  竹内孝治
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyoto Pharmaceutical University
胃・十二指腸アルカリ分泌の神経性調節の関する研究:コリン作動性機構の解明Principal Investigator
- Principal Investigator
  
  竹内孝治
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyoto Pharmaceutical University
胃運動性異常に起因する粘膜局所機能の変化及び損傷発生への関連性Principal Investigator
- Principal Investigator
  
  竹内孝治
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyoto Pharmaceutical University
Fluctuations of the gastric mucosal defensive ability during acid secretory states: Protective and deleterious actions of histamine on the rat gastric mucosaPrincipal Investigator
- Principal Investigator
  
  TAKEUCHI Koji
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyoto Pharmacuetical University, Department of Applied Pharmacology

All 2011 2010 2009 2007 2006 2005 2004 2003

All Journal Article Presentation Book

[Book] Physiology of Gastrointestinai Tract2011
- Author(s)
  Takeuchi, et al
- Publisher
  Academic Press(in press)
- Data Source
  KAKENHI-PROJECT-20590264
[Book] Advanced Gas Biology for Medical and Clinical Practice2011
- Author(s)
  Takeuchi, et al
- Total Pages
  10
- Publisher
  Karger Publisher
- Data Source
  KAKENHI-PROJECT-20590264
[Book] Physiology of Gastrointestinal Tract2011
- Author(s)
  Takeuchi, et al
- Publisher
  Academic Press(in press)
- Data Source
  KAKENHI-PROJECT-20590264
[Book] Advances Clinical Chemistry. Prostaglandin EP receptors and their roles in mucosal protection and ulcer healing in the gastrointestinal tract.2010
- Author(s)
  Takeuchi
- Publisher
  Academic Press(in press)
- Data Source
  KAKENHI-PROJECT-20590264
[Book] Advances Clin Chem2010
- Author(s)
  Takeuchi K
- Total Pages
  23
- Publisher
  Academic Press
- Data Source
  KAKENHI-PROJECT-20590264
[Book] Advances in Clinical Chemistry2010
- Author(s)
  Takeuchi K.
- Total Pages
  23
- Publisher
  Academic Press
- Data Source
  KAKENHI-PROJECT-20590264
[Book] DDW 2007 Session Handout Book2007
- Author(s)
  Takeuchi
- Publisher
  米国消化器病学会
- Data Source
  KAKENHI-PROJECT-18590248
[Journal Article] Regulatory mechanism of duodenal bicarbonate secretion : Roles of endogenous prostaglandins and nitric oxide.2011
- Author(s)
  Takeuchi, et al.
- Journal Title
  
  Pharmacol & Therapeutics
  
  Volume: 130 Pages: 59-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590264
[Journal Article] Stimulation of duodenal HCO_3^- secretion by hydrogen sulfide in rats : Relation to prostaglandins, nitric oxide and sensory neuron.2011
- Author(s)
  Ise F, Takasuka H, Hayashi S, Takahashi K, Koyama M, Aihara E, Takeuchi K
- Journal Title
  
  Acta Physiologica 201
  
  Pages: 117-126
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590264
[Journal Article] Carbon monoxide involvedin modulating HCO_3^- secretion in rat duodenums.2011
- Author(s)
  Takasuka H, Hayashi S, Koyama M, Yasuda M, Aihara E, Amagase K. Takeuchi K
- Journal Title
  
  J Pharmacol Exp Ther 337(in press)
  
  Pages: 293-300
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590264
[Journal Article] Regulatory mechanism of duodenal bicarbonate secretion : Roles of endogenous prostaglandins and nitric oxide.2011
- Author(s)
  Takeuchi K, Kita K, Hayashi S, Aihara E
- Journal Title
  
  Pharmacology & Therapeutics 130
  
  Pages: 59-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590264
[Journal Article] Prostaglandin EP receptor subtypes involved in regulating HCO_3^- secretion from gastroduodenal mucosa.2010
- Author(s)
  Takeuchi, et al.
- Journal Title
  
  Current Pharmaceutical Design
  
  Volume: 167 Pages: 1241-1251
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590264
[Journal Article] 十二指腸アルカリ分泌におけるCOの影響2010
- Author(s)
  高須賀洋徳、小山真史、林周作、粟飯原永太郎、竹内孝治
- Journal Title
  
  Ulcer Research 37
  
  Pages: 144-148
- NAID
  10027081619
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590264
[Journal Article] Prostaglandin EP receptor subtypes involved in regulating HCO_3^- secretion from gastroduodenal mucosa.2010
- Author(s)
  Takeuchi, et al.
- Journal Title
  
  Current Pharmaceutical Design 18(in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590264
[Journal Article] Phosphodiesterase isozymes involved in regulating acid secretion in the isolated mouse stomach.2009
- Author(s)
  Okuda S, Honda M, Ito Y, Aihara E, Kato S, Mitsufuji S, Yoshikawa T., Takeuchi K
- Journal Title
  
  J Physiol Pharmacol 60
  
  Pages: 183-190
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590264
[Journal Article] 十二指腸重炭酸イオン分泌におけるブラジキニンの影響2009
- Author(s)
  大橋由美、高須賀洋徳、高橋健人、粟飯原永太郎、竹内孝治
- Journal Title
  
  Ulcer Research 36
  
  Pages: 207-210
- NAID
  10025597155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590264
[Journal Article] Stimulatory action of sparkling water on gastroduodenal HCO_3^- secretion in rats2007
- Author(s)
  Yoko Sasaki, Eitaro Aihara, Fumitaka Ise and Koji Takeuchi
- Journal Title
  
  Ulcer Research 34
  
  Pages: 15-18
- NAID
  10019501702
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590248
[Journal Article] Involvement of prostaglandin E receptor EP3 subtype in duodenal bicarbonate secretion in rats.2007
- Author(s)
  Eitaro Aihara, Yoko Nomura, Yoko Sasaki, Fumitaka Ise, Kazutomo Kita, Koji Takeuchi
- Journal Title
  
  Life Sci. 80
  
  Pages: 2446-2453
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590248
[Journal Article] Effect of (S)-4-(1-(5-chloro-2-(4-fluorophenyoxy)benzamido)ethyl)benzoic acid (CJ-42794),a selective antagonist of prostaglandin E receptor subtype 4,0nulcerogenic and healing responses in rat gastrointestinal mucosa2007
- Author(s)
  Takeuchi, et. al.
- Journal Title
  
  Journal of Pharmacology and Experimental Therapeutics 322
  
  Pages: 903-912
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590248
[Journal Article] Stimulatory effect of Coca-Cola on gastroduodenal HCO_<3-> secretion in rats.2007
- Author(s)
  Yoko Sasaki, Eitaro Aihara, Fumitaka Ise, Kazutomo Kita, Koji Takeuchi
- Journal Title
  
  Inflammopharmacology 15
  
  Pages: 223-228
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590248
[Journal Article] Involvement of prostaglandin E receptor EP3 subtype in duodenal bicarbonate secretion in rats2007
- Author(s)
  Eitaro Aihara, Yoko Nomura, Yoko Sasaki, Fumitaka Ise, Kazutomo Kita and Koji Takeuchi
- Journal Title
  
  Life Sci. 80
  
  Pages: 2446-2453
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590248
[Journal Article] Phosphodiesterase isozymes involved in regulation of HCO_3^- secretion in isolated mouse duodenum in vitro2007
- Author(s)
  Masamune Hayashi, Kazutomo Kita, Yumi Ohashi, Eitaro Aihara and Koji Takeuchi
- Journal Title
  
  Biochem.Pharmacol. 74
  
  Pages: 1507-1513
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590248
[Journal Article] Phosphodiesterase isozymes involved in regulation of HCO_<3-> secretion in isolated mouse duodenum in vitro.2007
- Author(s)
  Masamune Hayashi, Kazutomo Kita, Yumi Ohashi, Eitaro Aihara, Koji Takeuchi
- Journal Title
  
  Biochem. Pharmacol. 74
  
  Pages: 1507-1513
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590248
[Journal Article] Stimulatory action of sparkling water on gastroduodenal HCO_3-secretion in rats.2007
- Author(s)
  Yoko Sasaki, Eitaro Aihara, Fumitaka Ise, Koji Takeuchi
- Journal Title
  
  Ulcer Research 34
  
  Pages: 15-18
- NAID
  10019501702
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590248
[Journal Article] Stimulatory effect of Coca-Cola on gastroduodenal HCO_3^- secretion in rats2007
- Author(s)
  Yoko Sasaki, Eitaro Aihara, Fumitaka Ise, Kazutomo Kita and Koji Takeuchi
- Journal Title
  
  Inflammopharmacology 15
  
  Pages: 223-228
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590248
[Journal Article] Stimulation by bradykinin of HCO_<3-> secretion in rat gastroduodenal mucosa.2006
- Author(s)
  Eitaro Aihara, Masamune Hayashi, Yoko Nomura, Shinichi Kato, Koji Takeuchi
- Journal Title
  
  Med. Sci. Monit. 12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590248
[Journal Article] Mucosal protective action of prostaglandin E_22006
- Author(s)
  Koji Takeuchi.
- Journal Title
  
  the alimentary tract and EP receptor subtypes.In "Discoveries in Gastroenterology"., Akademiai Kiado,Budapest
  
  Pages: 585-626
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590248
[Journal Article] Distinct mechanisms of acid-induced HCO_3^- secretion in normal and slightly permeable stomachs2006
- Author(s)
  Eitaro Aihara, Yoko Sasaki, Fumitaka Ise, Kazutomo Kita, Yoko Nomura and Koji Takeuchi
- Journal Title
  
  Am.J.Physiol. 291
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590248
[Journal Article] Involvement of cyclooxygenase-1, prostaglandin E_2 and EP1 receptors in acid-induced HCO_3 secretion in stomach2006
- Author(s)
  Takeuchi et al.
- Journal Title
  
  Journal of Physiology and Pharmacology 56
  
  Pages: 661-676
- Data Source
  KAKENHI-PROJECT-18590248
[Journal Article] Involvement of cyclooxygenase-1, prostaglandin E_2 and EP1 receptors in acid-induced HCO_<3-> secretion in stomach.2006
- Author(s)
  Koji Takeuchi, Eitaro Aihara, Yoko Sasaki, Yoko Nomura, Fumitaka Ise
- Journal Title
  
  J. Physiol. Pharmacol. 57
  
  Pages: 661-676
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590248
[Journal Article] Involvement of cyclooxygenase-1,prostaglandin E_2 and EP1 receptors in acid-induced HCO_3^- secretion in stomach2006
- Author(s)
  Koji Takeuchi, Eitaro Aihara, Yoko Sasaki, Yoko Nomura and Fumitaka Ise
- Journal Title
  
  J.Physiol.Pharmacol. 57
  
  Pages: 661-676
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590248
[Journal Article] Gastric HCO_<3-> secretion induced by mucosal acidification : different mechanisms depending on acid concentration.2006
- Author(s)
  Yoko Sasaki, Eitaro Aihara, Masamune Hayashi, Koji Takeuchi
- Journal Title
  
  Ulcer Research 33
  
  Pages: 189-191
- NAID
  10018262464
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590248
[Journal Article] Stimulation by dradykinin of HCO_3^- secretion in rat gastroduodenal mucosa2006
- Author(s)
  Eitaro Aihara, Masamune Hayashi, Yoko Nomura, Shinichi Kato and Koji Takeuchi
- Journal Title
  
  Med.Sci.Monit. 12
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590248
[Journal Article] Distinct mechanisms of acid-induced HCO_<3-> secretion in normal and slightly permeable stomachs.2006
- Author(s)
  Eitaro Aihara, Yoko Sasaki, Fumitaka Ise, Kazutomo Kita, Yoko Nomura, Koji Takeuchi
- Journal Title
  
  Am. J. Physiol. 291
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590248
[Journal Article] Mucosal protective action of prostaglandin E_2 in the alimentary tract and EP receptor subtypes.2006
- Author(s)
  Koji Takeuchi
- Journal Title
  
  In Discoveries in Gastroenterology , ed. : Gyula Mozsik,(Akademiai Kiado, Budapest)
  
  Pages: 585-626
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590248
[Journal Article] Gastric HCO_3^- secretion induced by mucosal acidification:different mechanisms depending on acid concentration2006
- Author(s)
  Yoko Sasaki, Eitaro Aihara, Masamune Hayashi and Koji Takeuchi
- Journal Title
  
  Ulcer Research 33
  
  Pages: 189-191
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590248
[Journal Article] Gastric HCO_<3-> secretion induced by mucosal acidification : different mechanisms depending on acid concentration.2005
- Author(s)
  Eitaro Aihara, Masamune Hayashi, Yoko Sasaki, Koji Takeuchi
- Journal Title
  
  Inflammopharmacology 13
  
  Pages: 179-190
- NAID
  10018262464
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590248
[Journal Article] Functional Mechanism Underlying COX-2 Expression in Rat Small Intestine Following Administration of Indomethacin : Relation to Intestinal Hypermotility.2005
- Author(s)
  Akiko Tanaka, Matsumoto Masahiro, Yujiro Hayashi, Koji Takeuchi
- Journal Title
  
  J Gastroentrol Hepatol 20
  
  Pages: 38-45
- Data Source
  KAKENHI-PROJECT-15790273
[Journal Article] Mechanisms underlying capsaicin-stimulated HCO_<3-> secretion in the stomach : comparison with mucosal acidification.2005
- Author(s)
  Eitaro Aihara, Masamune Hayashi, Yoko Sasaki, Atsushi Kobata, Koji Takeuchi
- Journal Title
  
  J. Pharmacol. Exp. Ther. 315
  
  Pages: 423-432
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590248
[Journal Article] Role of prostaglandin E receptor subtypes in gastroduodenal HCO_<3-> secretion.2005
- Author(s)
  Koji Takeuchi, Eitaro Aihara, Masamune Hayashi, Yoko Sasaki
- Journal Title
  
  Medicinal Chemistry 1
  
  Pages: 395-403
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590248
[Journal Article] Induction of small intestinal damage in rats following combined treatment with selective cyclooxygenase-2 and nitric oxide synthase inhibitors.2004
- Author(s)
  Ryoko Ohno, Aya Yokota, Akiko Tanaka, Koji Takeuchi.
- Journal Title
  
  J.Pharmacol.Exp.Ther. 310
  
  Pages: 821-827
- Data Source
  KAKENHI-PROJECT-15790273
[Journal Article] Functional mechanism underlying COX-2 expression following administration of indomethacin in rat stomachs : Importance of gastric Hypermotility.2004
- Author(s)
  Koji Takeuchi, Akiko Tanaka, Masahiro Matsumoto, Yujiro Hayashi.
- Journal Title
  
  Dig.Dis.Sci. 49
  
  Pages: 180-187
- Data Source
  KAKENHI-PROJECT-15790273
[Journal Article] Role of COX inhibition in pathogenesis of NSAID-induced small intestinal damage.2003
- Author(s)
  Koji Takeuchi, Akiko Tanaka, Ryoko Ohno, Aya Yokota.
- Journal Title
  
  J.Physiol.Pharmacol. 54
  
  Pages: 165-182
- Data Source
  KAKENHI-PROJECT-15790273
[Journal Article] COX inhibition and NSAID-induced gastric damage.2003
- Author(s)
  Koji Takeuchi, Akiko Tanaka, Ryoko Ohno, Masahiro Matsumoto
- Journal Title
  
  Current Topics in Pharmacology 6
  
  Pages: 69-81
- Data Source
  KAKENHI-PROJECT-15790273
[Presentation] Role of nitric oxide in the regulatory mechanisms of gastroduodenal HCO_3^- recretion.2010
- Author(s)
  Takeuchi K
- Organizer
  The 6^<th> International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide
- Place of Presentation
  国立京都国際会館(京都府)
- Year and Date
  2010-06-15
- Data Source
  KAKENHI-PROJECT-20590264
[Presentation] 十二指腸アルカリ分泌におけるムスカリン受容体の関与2010
- Author(s)
  小山真史、高橋健人、喜多一智、林周作、松井稔、竹内孝治
- Organizer
  第6回日本消化管学会総会学術集会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2010-02-19
- Data Source
  KAKENHI-PROJECT-20590264
[Presentation] Muscarinic acetylcholine receptor subtypes involved in carbachol-induced HCO_3^- secretion in mouse duodenum in Vitro.2010
- Author(s)
  Takeuchi, et al
- Organizer
  16^<th> World Congress on Basic and Clinical Pharmacology
- Place of Presentation
  Copenhagen, Denmark
- Year and Date
  2010-07-15
- Data Source
  KAKENHI-PROJECT-20590264
[Presentation] 胃酸分泌の調節におけるホスホジエステラーゼ(PDE)アイソザイムの関与2010
- Author(s)
  本田真弥、奥田さやか、出原千歳、加藤伸一、竹内孝治
- Organizer
  第28回Cytoprotection研究会
- Place of Presentation
  ホテルグランビア京都
- Year and Date
  2010-03-05
- Data Source
  KAKENHI-PROJECT-20590264
[Presentation] マウス胃酸分泌におけるカルシウム感知受容体(CaSR)の役割2010
- Author(s)
  土岸広治、小山真史、林周作、栗飯原永太郎、加藤伸一、竹内孝治
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2010
- Place of Presentation
  京都大学
- Year and Date
  2010-09-11
- Data Source
  KAKENHI-PROJECT-20590264
[Presentation] 粘膜酸性化による十二指腸アルカリ分泌の増大における性差2010
- Author(s)
  小山真史、大橋由美、高須賀洋徳、粟飯原永太郎、竹内孝治
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2010-03-16
- Data Source
  KAKENHI-PROJECT-20590264
[Presentation] Activation of muscarinic acetylcholine receptor subtype 4 is essential for carbachol-induced pepsinogen secretion in mice : relation to D cells/somatostatin.2010
- Author(s)
  Takeuchi, et al
- Organizer
  American Gastroenterological Association
- Place of Presentation
  New Orleans, USA
- Year and Date
  2010-05-02
- Data Source
  KAKENHI-PROJECT-20590264
[Presentation] 胃酸分泌におけるカルシウム感知受容体の関与2010
- Author(s)
  高須賀洋徳、林周作、倉田直人、粟飯原永太郎、竹内孝治
- Organizer
  第6回日本消化管学会総会学術集会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2010-02-19
- Data Source
  KAKENHI-PROJECT-20590264
[Presentation] 胃酸分泌におけるカルシウム感知受容体の関与2010
- Author(s)
  小山真史、加藤伸一、竹内孝治
- Organizer
  第38回日本潰瘍学会
- Place of Presentation
  リーガロイヤルホテル大阪
- Year and Date
  2010-11-19
- Data Source
  KAKENHI-PROJECT-20590264
[Presentation] Prostaglandin EP receptor subtypes and phosphodiesterase isozymes involved in the regulation of gastroduodenal bicarbonate secretion.2009
- Author(s)
  Takeuchi
- Organizer
  Acta Physisologica International Symposium. Acid-Base Transporters and Epithelial Electrolyte Transport
- Place of Presentation
  Uppsala, Sweden
- Year and Date
  2009-08-12
- Data Source
  KAKENHI-PROJECT-20590264
[Presentation] Muscarinic acetylcholine receptor subtypes involved in carbachol-induced HCO_3^- secretion in mouse duodenum in vitro.2009
- Author(s)
  Takeuchi
- Organizer
  Scandinavian Physiological Society Annual Meeting
- Place of Presentation
  Uppsala, Sweden
- Year and Date
  2009-08-14
- Data Source
  KAKENHI-PROJECT-20590264

1. KATO Shinichi (90281500)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
2. TANAKA Akiko (30329940)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
3. SHIBATA Nobuhito (60319449)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. TAKADA Kanji (30102106)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. YOSHIKAWA Yukako (30278444)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. KURIHARA Eitaro

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. SASAKI Yoko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KITA Kazutomo

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. ISE Fumitaka

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. OHASHI Yumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. TAKASUKA Hironori

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
12. TAKAHASHI Kento

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
13. KOYAMA Masafumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results

TAKEUCH Koji 竹内 孝治

TAKEUCHI Koji 竹内 孝治

Research Projects

Research Products

Co-Researchers

Local regulatory mechanisms of gastroduodenal bicarbonate secretion :Principal Investigator

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Signalling pathways and transporters involved in gastroduodenal bicarbonate secretionPrincipal Investigator

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非ステロイド系抗炎症薬(NSAIDs)による胃腸傷害の発生とCOX阻害との関連性-COX-1阻害により誘導されるCOX-2の役割と誘導機序-

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Distribution of vanilloid receptors (VR1) in gastrointestinal tract and their role in mucosal protection mediated by capsaicin-sensitive afferent neuronsPrincipal Investigator

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Protection against dextran sulfate sodium-induced colitis by microsheres of polyphenol (ellagic acid)Principal Investigator

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Development of NSAIDs that spare gastrointestinal tract injury.-COX-2 selective and NO-releasing NSAIDs-Principal Investigator

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Regulatory mechanism of acid secretory response in the stomach following injury : Role of nitric oxide.Principal Investigator

Principal Investigator

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傷害胃粘膜における胃酸分泌変化とその調節機構に関する研究:Nitric Oxideの役割Principal Investigator

Principal Investigator

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傷害胃粘膜における胃酸分泌変化とその調節機構に関する研究Principal Investigator

Principal Investigator

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Research Institution

胃粘膜の適応性反応における内皮由来血管弛緩因子(Nitric Oxide)の役割Principal Investigator

Principal Investigator

Project Period (FY)

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カプサイシン感受性知覚神経を介する胃粘膜血流調節の生理学的意義に関する研究Principal Investigator

Principal Investigator

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胃・十二指腸の適応性反応におけるカプサイシン感受性神経の役割Principal Investigator

Principal Investigator

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胃・十二指腸アルカリ分泌の神経性調節の関する研究:コリン作動性機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

TAKEUCH Koji 竹内孝治

TAKEUCHI Koji 竹内孝治