KAI Masaaki 甲斐雅亮

Researcher Number	00160953
Affiliation (based on the past Project Information) *help	2014 – 2016: 長崎大学, 医歯薬学総合研究科(薬学系), 教授 2011 – 2013: 長崎大学, 医歯(薬)学総合研究科, 教授 2007 – 2010: Nagasaki University, 大学院・医歯薬学総合研究科, 教授 2005 – 2006: 長崎大学, 大学院医歯薬学総合研究科, 教授 2002 – 2005: 長崎大学, 大学院・医歯薬学総合研究科, 教授 … More 1998 – 2001: 長崎大学, 薬学部, 教授 1996 – 1997: 九州大学, 薬学部, 助教授 1992 – 1993: 九州大学, 薬学部, 助手 Less
Review Section/Research Field	Principal Investigator Physical pharmacy / Biological Sciences / Laboratory medicine / Laboratory medicine / Biological Sciences / Analytical chemistry Except Principal Investigator Drug development chemistry
Keywords	Principal Investigator DNA / 高感度検出 / マイクロアレー / Chemiluminescence / 化学発光 / 核酸 / 遺伝子 / mRNA / 化学発光検出 / Sensitive detection … More / Selective detection / ペプチド / 蛍光反応 / 変異 / DNAチップ / バイオテクノロジー / 高分子プローブ / 高分子合成 / ハイブリダイゼーション / Luminescent probe / Macromolecular probe / Development of technology / DNA analysis / Nucleic acid probe / Dextran probe / 解析 / プローブ / 高分子化合物 / 発光試薬 / 発光プローブ / 技術開発 / DNA解析 / 核酸プローブ / 超高感度検出 / デキストランプローブ / Tryptophan / Derivatization / Inquiry / Chromatography / Peptide / 誘導体化反応 / 誘動体化反応 / 高感度 / 化学発光法 / クロマドグラフィー / トリプトファン / 誘導体化 / 探索 / クロマトグラフィー / 特異的検出 / Hybridization / CCD camera / Arylglyoxalreagents / Imaging detection / Nucleic acid / 選択的検出 / CCDカメラ / アリールグリオキサール試薬 / 画像検出 / Sensitive analysis / Selective reagent / Phenylglyoxal / Chemiluminescence detection / Fluorescence detection / High-performance liquid chromatography / Nucleic acid-related compound / Guanine / 高感度分析 / 選択的試薬 / フェニルグリオキサール / 蛍光検出 / 高速液体クロマトグラフィー / 核酸関連物質 / グアニン / がん / 癌 / メチル化 / ヒストン / エピゲノム / クロマチン / 薬物耐性 / エイズ / 基質特異性 / プロテアーゼ / 薬剤耐性 / HIV / エイズ検査 / 蛋白質 / 物理化学的性質 / マイクロアレイ / 発光検出 / タンパク質 / 感染症 / アプタマー / プリオン / ペプチド検出 / 新規蛍光反応 / ペプチドホルモン / ホウ酸塩試薬 / カテコール試薬 / ペプチド認識反応 / 蛍光検出反応 / プロテインチップ / 高分子発光プローブ / プルラン / ビオチン / イソルミノール / 核酸検出 / 化学発光性プローブ / 水溶性高分子 / デキストラン / エドマン試薬 / CIPIC / 超微量分析 / ペプチドシーケンス / エドマン分解法 / アミノ酸配列 … More Except Principal Investigator 薬剤耐性 / 変異 / CD4 / プロテアーゼ / siRNA / アプタマー / HIV / エイズ Less

新規エピゲノム分析によるクロマチン変異の解析Principal Investigator
- Principal Investigator
  
  甲斐雅亮
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Nagasaki University
Development of the anti-AIDS drug using aptamer-siRNA
- Principal Investigator
  
  KABASHIMA Tsutomu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Nagasaki University
Development of the discrimination method for mutation and drug resistance of an AIDS virusPrincipal Investigator
- Principal Investigator
  
  KAI Masaaki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Laboratory medicine
- Research Institution
  Nagasaki University
Development of a novel detection method for abnormal prion proteinPrincipal Investigator
- Principal Investigator
  
  KAI Masaaki
- Project Period (FY)
  2007 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Laboratory medicine
- Research Institution
  Nagasaki University
プロテインチップに用いる新しい蛍光検出反応の開発Principal Investigator
- Principal Investigator
  
  甲斐雅亮
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Analytical chemistry
- Research Institution
  Nagasaki University
新規高分子発光プローブによる発現遺伝子の超高感度マイクロアレー解析Principal Investigator
- Principal Investigator
  
  甲斐雅亮
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nagasaki University
新規高分子発光プローブによるmRNAのマイクロアレー解析Principal Investigator
- Principal Investigator
  
  甲斐雅亮
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nagasaki University
超高感度化学発光検出によるmRNAのマイクロアレー解析Principal Investigator
- Principal Investigator
  
  甲斐雅亮
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nagasaki University
核酸検出に用いる新規水溶性化学発光高分子プローブの創製Principal Investigator
- Principal Investigator
  
  甲斐雅亮
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Physical pharmacy
- Research Institution
  Nagasaki University
Development of Super-Sensitive Technique for the Detection of Nucleic Acids with Luminescent ReagentPrincipal Investigator
- Principal Investigator
  
  KAI Masaaki
- Project Period (FY)
  2002 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Physical pharmacy
- Research Institution
  Nagasaki University
アミノ酸配列決定に用いる新規化学発光ラベル化試薬の開発Principal Investigator
- Principal Investigator
  
  甲斐雅亮
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Physical pharmacy
- Research Institution
  Nagasaki University
Inquiry of trace amount of bioactive unknown peptides by specific chemiluminescent derivatization detectionPrincipal Investigator
- Principal Investigator
  
  KAI Masaaki
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  NAGASAKI UNIVERSITY
Development of a chemiluminescent reagent that recognizes guanine in nucleic acid, and its use for chemiluminescence detection of DNAPrincipal Investigator
- Principal Investigator
  
  KAI Masaaki
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  KYUSHU UNIVERSITY
Simultaneous and sensitive analytical methods of guanine-containing nucleic acid-related compounds by means of new selective fluoresence reactionPrincipal Investigator
- Principal Investigator
  
  KAI Masaaki
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  KYUSHU UNIVERSITY

[Book] 薬学物理化学演習　[第３版]（第５章　電解質溶液）2011
- Author(s)
  甲斐　雅亮
- Publisher
  廣川書店
- Data Source
  KAKENHI-PROJECT-23659302
[Book] 改定６版分析化学便覧　（第２章　2.1.3有機定性分析）2011
- Author(s)
  甲斐　雅亮
- Publisher
  丸善出版
- Data Source
  KAKENHI-PROJECT-23659302
[Book] 薬学物理化学演習 [第3版](第5章電解質溶液)2011
- Author(s)
  甲斐雅亮、椛島力
- Publisher
  廣川書店
- Data Source
  KAKENHI-PROJECT-23659302
[Book] 改定6版分析化学便覧 (第2章 2.1.3 有機定性分析)2011
- Author(s)
  甲斐雅亮
- Publisher
  丸善出版
- Data Source
  KAKENHI-PROJECT-23659302
[Book] 薬学物理化学[第5版](第5章電解質溶液pp79-98)2010
- Author(s)
  甲斐雅亮、椛島力(小野行雄編集)
- Total Pages
  379
- Publisher
  廣川書店
- Data Source
  KAKENHI-PROJECT-19209020
[Book] ベーシック分析化学 (第16章タンパク質と核酸の標識)2006
- Author(s)
  甲斐雅亮, 椛島力(その他15名共著)
- Total Pages
  260
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-17655035
[Book] ベーシック分析化学 (第16章タンパク質と核酸の標識)2006
- Author(s)
  甲斐雅亮, 椛島力(その他15名共著)
- Total Pages
  260
- Publisher
  化学同人
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14102031
[Book] 薬学物理化学 -第4版- (第7章界面とコロイド)(松島美一,吉柳節夫監修)2004
- Author(s)
  甲斐雅亮(共著)
- Total Pages
  362
- Publisher
  廣川書店株式会社
- Data Source
  KAKENHI-PROJECT-16011247
[Book] 薬理物理化学-第4版-(第7章界面とコロイド)(松島美一, 吉柳節夫監修)2004
- Author(s)
  甲斐雅亮(共著)
- Total Pages
  362
- Publisher
  廣川書店株式会社
- Data Source
  KAKENHI-PROJECT-14102031
[Journal Article] Fluorescence assay of dihydroorotate dehydrogenase that may become a cancer biomarker.2017
- Author(s)
  Yin S, Kabashima T, Zhu Q, Shibata T, Kai M
- Journal Title
  
  Sci Rep.
  
  Volume: 7 Issue: 1 Pages: 40670-40670
- DOI
  10.1038/srep40670
- NAID
  120006987578
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460146, KAKENHI-PROJECT-15K07892
[Journal Article] Facile preparation of streptavidin-coated sephadex beads and their application to chemiluminescence detection of a target DNA2015
- Author(s)
  El-Mahdy AF, Ejupi V, Shibata T, Kabashima T, Lu J, Kai M
- Journal Title
  
  Mcrochimica Acta
  
  Volume: 182 Issue: 3-4 Pages: 495-503
- DOI
  10.1007/s00604-014-1348-9
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23790051, KAKENHI-PUBLICLY-26116516, KAKENHI-PROJECT-26460146
[Journal Article] Spectrofluorometric Assays of Human Collagenase Activity Using Native Collagen and Acetyl-Peptide Substrates2015
- Author(s)
  Valon Ejupi, Shpend Dragusha, Tsutomu Kabashima, Qinchang Zhu, Ahmed F. M. El-Mahdy, Sheng Yin, Takayuki Shibata, Masaaki Kai
- Journal Title
  
  Advances in Enzyme Research
  
  Volume: 3 Issue: 01 Pages: 19-29
- DOI
  10.4236/aer.2015.31003
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-26116516, KAKENHI-PROJECT-26460146
[Journal Article] Chemiluminescence-imaging detection of DNA on a solid-phase membrane by using a peroxidase-labeled macromolecular probe2015
- Author(s)
  Md. Golam Azam, M. Yamasuji, T. Krawczyk, T. Shibata, T. Kabashima,M. Kai
- Journal Title
  
  Talanta
  
  Volume: 139 Pages: 138-142
- DOI
  10.1016/j.talanta.2015.03.005
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-26116516, KAKENHI-PROJECT-26460146
[Journal Article] Sensitive and Selective Determination of Orotic Acid in Biological Specimens Using a Novel Fluorogenic Reaction.2015
- Author(s)
  Yin S, Dragusha S, Ejupi V, Shibata T, Kabashima T, Kai M.
- Journal Title
  
  Journal of Fluorescence
  
  Volume: 25 Issue: 4 Pages: 1005-1011
- DOI
  10.1007/s10895-015-1584-3
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07892, KAKENHI-PROJECT-26460146, KAKENHI-PUBLICLY-26116516
[Journal Article] Fluorometric assay for phenotypic differentiation of drug-resistant HIV mutants.2015
- Author(s)
  Zhu Q, Yu Z, Kabashima T, Yin S, Dragusha S, El-Mahdy AF, Ejupi V, Shibata T, Kai M
- Journal Title
  
  Scientific Reports
  
  Volume: 5 Issue: 1 Pages: 10323-10323
- DOI
  10.1038/srep10323
- NAID
  120006987048
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07892, KAKENHI-PROJECT-26460146, KAKENHI-PUBLICLY-26116516
[Journal Article] Delivery of siRNA using siRNA/cationic vector complexes encapsulated in dendrimer-like polymeric DNAs2015
- Author(s)
  Ahmed F. M. El-Mahdy, Takayuki Shibata, Tsutomu Kabashima, Qinchang Zhu and Masaaki Kai
- Journal Title
  
  RSC Adv.
  
  Volume: 5 Issue: 41 Pages: 32775-32785
- DOI
  10.1039/c5ra01032b
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-26116516
[Journal Article] Sensitive and selective determination of peptides, PG and PGP, using a novel fluorogenic reagent 4-chlorobenzene-1,2-diol2015
- Author(s)
  Hasina Yasmin, Mohammed Shafikur Rahman, Takayuki Shibata,Tsutomu Kabashima, Masaaki Kai
- Journal Title
  
  Chemical Papers
  
  Volume: 69 Issue: 4 Pages: 504-509
- DOI
  10.1515/chempap-2015-0057
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-26116516, KAKENHI-PROJECT-26460146
[Journal Article] DNA aptamers in the diagnosis and treatment of human diseases.2015
- Author(s)
  Zhu Q, Liu G, Kai M
- Journal Title
  
  Molecules
  
  Volume: 20 Issue: 12 Pages: 20979-20997
- DOI
  10.3390/molecules201219739
- NAID
  120006987226
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26116516
[Journal Article] Selective, sensitive and fluorometric determination of urinary cytosine with 4-trifluoromethylbenzamidoxime and N, N-dimethylformamide2014
- Author(s)
  Dragusha S, Shibata T, Yin S, Fujita JY, Kabashima T, Kai M
- Journal Title
  
  Clin. Chim. Acta
  
  Volume: 429 Pages: 123-128
- DOI
  10.1016/j.cca.2013.11.027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590117, KAKENHI-PROJECT-23659302, KAKENHI-PROJECT-23790051
[Journal Article] Carbon Nanofiber-based Luminol-biotin Probe for Sensitive Chemiluminescence Detection of Protein2014
- Author(s)
  Baj S, Krawczyk T, Pradel N, Azam MG, Shibata T, Dragusha S, Skutil K, Pawlyta M, Kai M
- Journal Title
  
  Anal. Sci.
  
  Volume: 30 Issue: 11 Pages: 1051-1056
- DOI
  10.2116/analsci.30.1051
- NAID
  130004704337
- ISSN
  0910-6340, 1348-2246
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23790051, KAKENHI-PUBLICLY-26116516
[Journal Article] Dendrimer-like polymeric DNAs as chemiluminescence probes for amplified detection of telomere DNA on a solid-phase membrane2014
- Author(s)
  El-MandyAF, Shibata T, Kabashima T, Kai M
- Journal Title
  
  Chem. Commun.
  
  Volume: 50 Issue: 7 Pages: 859-861
- DOI
  10.1039/c3cc47454b
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590117, KAKENHI-PROJECT-23659302, KAKENHI-PROJECT-23790051
[Journal Article] Amplified and selective assay of collagens by enzymatic and fluorescent reactions2014
- Author(s)
  Yasmin H, Kabashima T, Rahman MS, Shibata T, Kai M
- Journal Title
  
  Scientific Reports
  
  Volume: 4 Issue: 1 Pages: 4950-4950
- DOI
  10.1038/srep04950
- NAID
  120006986568
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23790051, KAKENHI-PUBLICLY-26116516, KAKENHI-PROJECT-26460146
[Journal Article] A Novel Fluorometric Method for the Selective Determination of Pro-Gly and Pro-Gly-Pro2014
- Author(s)
  Yasmin H, Rahman MS, Shibata T, Kabashima T, Kai M
- Journal Title
  
  International Journal of Peptide Research and Therapeutics
  
  Volume: 20 Issue: 4 Pages: 441-446
- DOI
  10.1007/s10989-014-9406-z
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23790051, KAKENHI-PUBLICLY-26116516, KAKENHI-PROJECT-26460146
[Journal Article] A novel fluorescence reaction for N-terminal Ser-containing peptides and its application to assay caspase activity2013
- Author(s)
  Rahman MS, Kabashima T, Yasmin H, Shibata T, Kai M
- Journal Title
  
  Anal. Biochem.
  
  Volume: 433 Issue: 2 Pages: 79-85
- DOI
  10.1016/j.ab.2012.10.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590117, KAKENHI-PROJECT-23659302, KAKENHI-PROJECT-23790051
[Journal Article] Hybridization chain reaction-based instantaneous derivatization technology for chemiluminescence detection of specific DNA sequences2013
- Author(s)
  Wang X, Lau C, Kai M, Lu J
- Journal Title
  
  Analyst
  
  Volume: 138 Issue: 9 Pages: 2691-2697
- DOI
  10.1039/c3an36885h
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659302
[Journal Article] Selective FL quenching or enhancing of diimine ligands by guanine2013
- Author(s)
  Smanmoo S, Kawasaki S, Tangboriboonrat P, Shibata T, Kabashima T, Kai M
- Journal Title
  
  J. Fluoresc.
  
  Volume: 23 Issue: 5 Pages: 853-857
- DOI
  10.1007/s10895-013-1216-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590117, KAKENHI-PROJECT-23659302, KAKENHI-PROJECT-23790051
[Journal Article] Inhibition of HIV-1 protease expression in T cells owing to DNA aptamer-mediated specific delivery of s1RNA2012
- Author(s)
  Zhu Q, Shibata T, Kabashima T, Kai M
- Journal Title
  
  Eur. J. Med. Chem.
  
  Volume: 56 Pages: 396-399
- DOI
  10.1016/j.ejmech.2012.07.045
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590117, KAKENHI-PROJECT-23659302, KAKENHI-PROJECT-23790051
[Journal Article] Modulation of PC12 cell viability by forskolin-induced cyclic AMP levels through ERK and JNK pathways: An implication for L-DOPA-induced cytotoxicity in nigrostriatal dopamine neurons2012
- Author(s)
  K. H. Park
- Journal Title
  
  Toxicological Sciences
  
  Volume: 128(1) Issue: 1 Pages: 247-257
- DOI
  10.1093/toxsci/kfs139
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659302
[Journal Article] Selective and sensitive determination of peptides using 3, 4-dihydroxyphenylacetic acid as a fluorogenic reagent2012
- Author(s)
  Yasmin H, Shibata T, Rahman MS, Kabashima T, Kai M
- Journal Title
  
  Anal. Chim. Acta
  
  Volume: 721 Pages: 162-166
- DOI
  10.1016/j.aca.2012.01.035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590117, KAKENHI-PROJECT-23659302, KAKENHI-PROJECT-23790051
[Journal Article] Aptamer-barcode based immunoassay for the instantaneous derivatization chemiluminescence detection of IgE coupled to magnetic beads.2011
- Author(s)
  Peng Q, Cao Z, Lau C, Kai M, Lu J.
- Journal Title
  
  Analyst 136
  
  Pages: 140-147
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209020
[Journal Article] Alkaline phosphatase-labeled macromolecular probe for sensitive chemiluminescence detection of proteins on a solid-phase membrane2011
- Author(s)
  Azam MG, Shibata T, Kabashima T, Kai M
- Journal Title
  
  Anal. Bioanal. Chem.
  
  Volume: 401 Issue: 4 Pages: 1211-1217
- DOI
  10.1007/s00216-011-5196-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590117, KAKENHI-PROJECT-23659302, KAKENHI-PROJECT-23790051
[Journal Article] Sensitive chemiluminescence detection of prion protein on a membrane by using a peroxidase-labeled dextran probe2011
- Author(s)
  Azam G, Shibata T, Kabashima T, Kai M
- Journal Title
  
  Anal.Sci
  
  Volume: 27 Pages: 715-720
- NAID
  10029332555
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659302
[Journal Article] A manual sequence method of peptides and phosphopeptides using 4-(1'-cyanoisoindolyl)phenyliso thiocyanate2011
- Author(s)
  Shibata T, Wainaina MN, Miyoshi T, Kabashima T, Kai M
- Journal Title
  
  J. Chromatogr. A
  
  Volume: 1218 Issue: 24 Pages: 3757-3762
- DOI
  10.1016/j.chroma.2011.04.040
- NAID
  120006985100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590117, KAKENHI-PROJECT-23659302, KAKENHI-PROJECT-23790051
[Journal Article] Chemiluminescence detection of telomere DNA in human cells on a membrane by using fluorescein-5-isothiocyanate-labeled primers2011
- Author(s)
  Yamasuji M, Shibata T, Kabashima T, Kai M
- Journal Title
  
  Anal. Biochem.
  
  Volume: 413 Issue: 1 Pages: 50-54
- DOI
  10.1016/j.ab.2011.01.047
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590117, KAKENHI-PROJECT-23659302, KAKENHI-PROJECT-23790051
[Journal Article] Mechanisms of L-DOPA-induced cytotoxicity in rat adrenal pheochromocytoma cells : implication of oxidative stress-related kinases and cyclic AMP.2010
- Author(s)
  Jin CM, Yang YJ, Huang HS, Kai M, Lee MK.
- Journal Title
  
  Neuroscience 170
  
  Pages: 390-398
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209020
[Journal Article] Alginic acid-based macromolecular chemiluminescent probe for universal protein assay on a solid-phase membrane.2010
- Author(s)
  Krawczyk T, Kondo M, Azam MG, Zhang H, Shibata T, Kai M.
- Journal Title
  
  Analyst 135
  
  Pages: 2894-2900
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209020
[Journal Article] A novel and specific fluorescence reaction for uracil.2010
- Author(s)
  Shibata T, Kawasaki SY, Fujita JY, Kabashima T, Kai M.
- Journal Title
  
  Anal.Chim.Acta 674
  
  Pages: 234-238
- NAID
  120006984283
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209020
[Journal Article] G-rich sequence-functionalized polystyrene microsphere-based instantaneous derivatization for the chemiluminescent amplified detection of DNA.2010
- Author(s)
  Xin L, Cao Z, Lau C, Kai M, Lu J.
- Journal Title
  
  Luminescence 25
  
  Pages: 336-342
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209020
[Journal Article] Aptamer-mediated chemiluminescence detection of prion protein on a membrane using trimethoxyphenylglyoxal.2010
- Author(s)
  Hossain MT, Shibata T, Kabashima T, Kai M.
- Journal Title
  
  Anal.Sci. 26
  
  Pages: 645-647
- NAID
  10026783879
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209020
[Journal Article] Selective and facile assay of human immunodeficiency virus protease activity by a novel fluorogenic reaction.2010
- Author(s)
  Yu Z, Kabashima T, Tang C, Shibata T, Kitazato K, Kobayashi N, Lee MK, Kai M.
- Journal Title
  
  Anal.Biochem. 397
  
  Pages: 197-201
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209020
[Journal Article] Diimine ligand as a novel chemiluminescence enhancer of luminol-containing compounds.2009
- Author(s)
  Smanmoo C, Yamasuji M, Sagawa T, Shibata T, Kabashima T, Yuan DQ, Fujita K, Kai M.
- Journal Title
  
  Talanta 77
  
  Pages: 1761-1766
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209020
[Journal Article] Facile detection of proteins on a solid-phase membrane by direct binding of dextran-based luminol-biotin chemiluminescent polymer.2009
- Author(s)
  Zhang H, Shibata T, Krawczyk T, Kabashima T, Lu J, Lee MK, Kai M.
- Journal Title
  
  Talanta 79
  
  Pages: 700-705
- NAID
  120006984124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209020
[Journal Article] Facile detection of proteins on a solid-phase membrane by direct binding of dextran-based luminol-biotin chemiluminescent polymer2009
- Author(s)
  Huan Zhang, Takayuki Shibata, Tomasz Krawczyk, Tsutomu Kabashima, Jianzhong Lu, Myung K. Leec, Masaaki Kai
- Journal Title
  
  Talanta 79(3)
  
  Pages: 700-705
- NAID
  120006984124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209020
[Journal Article] Label-free aptamer-based chemiluminescence detection of adenosine.2009
- Author(s)
  Yan X, Cao Z, Kai M, Lu J.
- Journal Title
  
  Talanta 79
  
  Pages: 383-387
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209020
[Journal Article] Chemiluminescence platforms in immunoassay and DNA analyses.2009
- Author(s)
  Fan A, Cao Z, Li H, Kai M, Lu J.
- Journal Title
  
  Anal.Sci. 25
  
  Pages: 587-597
- NAID
  10025211962
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209020
[Journal Article] Facile assay of telomerase activity utilizing a DNA-detectable chemiluminogenic reagent.2008
- Author(s)
  Tonooka K, Kabashima T, Shibata T, Tang C, Yu Z, Kai M.
- Journal Title
  
  Anal.Sci. 24
  
  Pages: 471-475
- NAID
  10021099521
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209020
[Journal Article] Fluorescence detection of amino acids in the postcleavage conversions for manual sequencing of a peptide.2008
- Author(s)
  Wainaina MN, Shibata T, Smanmoo C, Kabashima T, Kai M.
- Journal Title
  
  Anal.Biochem. 374
  
  Pages: 423-425
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209020
[Journal Article] A selective fluorescence reaction for peptides and chromatographic analysis.2008
- Author(s)
  Kabashima T, Yu Z, Tang C, Nakagawa Y, Okumura K, Shibata T, Lu J, Kai M.
- Journal Title
  
  Peptides 29
  
  Pages: 356-363
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209020
[Journal Article] Induction of dopamine biosynthesis by 1-DOPA in PC12 cells : implications of L-DOPA influx and cyclic AMP.2008
- Author(s)
  Jin CM, Yang YJ, Huang HS, Lim SC, Kai M, Lee MK.
- Journal Title
  
  Eur.J.Pharmacol. 591
  
  Pages: 88-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209020
[Journal Article] Dextran-based polymeric chemiluminescent compounds for the sensitive optical imaging of a cytochrome p450 protein on a solid-phase membrane.2007
- Author(s)
  Zhang H, Smanmoo C, Kabashima T, Lu J, Kai M.
- Journal Title
  
  Angew.Chem.Int.Ed.Engl. 46
  
  Pages: 8226-8229
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209020
[Journal Article] Facile determination of DNA-binding nuclear factor-KB by chemiluminescence detection.2007
- Author(s)
  K.Tonooka, T.Kabashima, M.Yamasuji, M.Kai
- Journal Title
  
  Anal. Biochem. 364
  
  Pages: 30-36
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14102031
[Journal Article] Facile determination of DNA-binding nuclear factor-kappaB by chemiluminescence detection.2007
- Author(s)
  Tonooka K, Kabashima T, Yamasuji M, Kai M.
- Journal Title
  
  Anal.Biochem. 364
  
  Pages: 30-36
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209020
[Journal Article] Dextran-based polymeric chemiluminescent compounds for the sensitive optical imaging of a cytochrome P450 protein on a solid-phase membrane2007
- Author(s)
  Huan Zhang, Chaivat Smanmoo, Tsutomu Kabashima, Jianzhong Lu, Masaaki Kai
- Journal Title
  
  Angew.Chem.Int.Ed. 46(43)
  
  Pages: 8226-8229
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209020
[Journal Article] Cerium complexes of cyclodextrin dimers as efficient catalysts for luminol chemiluminescence reactions.2007
- Author(s)
  Yuan DQ, Lu J, Atsumi M, Yan JM, Kai M, Fujita K.
- Journal Title
  
  Org.Biomol.Chem. 5
  
  Pages: 2932-2939
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209020
[Journal Article] Chemiluminescence detection of amino acids using an Edman-type reagent, 4-(1'-cyanoisoindolyl) phenylisothiocyanate.2005
- Author(s)
  M.Kai, M.Morizono, M.N.Wainaina, T.Kabashima, M.K.Lee, J.Lu
- Journal Title
  
  Anal. Chim. Acta 535
  
  Pages: 153-159
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14102031
[Journal Article] Magnetic bead-based label-free chemiluminescence detection of specific DNA sequence-telomere.2005
- Author(s)
  Z.-J.Cao, Y.Xia, M.Kai, J.Lu
- Journal Title
  
  Acta Chim. Sinica 63
  
  Pages: 407-410
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14102031
[Journal Article] Chemiluminescence detection of amino acids using an Edman-type reagent,4-(1'-cyanoisoindolyl)phenylisothiocyanate2005
- Author(s)
  Masaaki Kai
- Journal Title
  
  Anal.Chim.Acta 535
  
  Pages: 153-159
- Data Source
  KAKENHI-PROJECT-14102031
[Journal Article] Chemiluminescence detection of amino acids using an Edman-type reagent, 4-(1'-cyanoisoindolyl)phenylisothiocyanate2005
- Author(s)
  Masaaki Kai
- Journal Title
  
  Anal.Chim.Acta 535
  
  Pages: 153-159
- Data Source
  KAKENHI-PROJECT-17655035
[Journal Article] Chemiluminescence detection of amino acids using an Edman-type reagent, 4-(1'-cyanoisoindolyl)phenylisothio cyanate2005
- Author(s)
  Masaaki Kai(その他5名共著)
- Journal Title
  
  Anal.Chim.Acta 535
  
  Pages: 153-159
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14102031
[Journal Article] Enantio-selective inhibition of (1R,9S )-and (1S,9R)-β-hydrastines on dopamine biosynthesis in PC12 cells2004
- Author(s)
  S.Y.Yin, Y.M.Kim, J.J.Lee, C.M.Jin, Y.J.Yang, J.J.Ma, M.H.Kang, M.Kai, M.K.Lee
- Journal Title
  
  Neuropharmacol. 47
  
  Pages: 1045-1052
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14102031
[Journal Article] Chemiluminescence determination of tetracycline based on radical production in a basic acetonitrile-hydrogen peroxide reaction.2004
- Author(s)
  C.Lau, J.Lu, M.Kai
- Journal Title
  
  Anal. Chim. Acta 503
  
  Pages: 235-239
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14102031
[Journal Article] Chromatographic determinations of a 6-lactam antibiotic, cefaclor by means of fluorescence, chemiluminescence and mass spectrometry.2003
- Author(s)
  Masaaki Kai, Hiromi Kinoshita, Mikio Morizono
- Journal Title
  
  Talanta 60
  
  Pages: 325-334
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14102031
[Journal Article] Magnetic bead-based label-free chemiluminescence detection of telomeres.2003
- Author(s)
  J.Lu, C.Lau, M.Kai
- Journal Title
  
  Chem. Commun.
  
  Pages: 2888-2889
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14102031
[Journal Article] A simple and sensitive chemiluminescence method for the determination of tiopronin for a pharmaceutical formulation.2003
- Author(s)
  J.Lu, C.Lau, S.Yagisawa, K.Ohta, M.Kai
- Journal Title
  
  J. Pharm. Biomed. Anal. 33
  
  Pages: 1033-1038
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14102031
[Journal Article] Sensitive determination of a β-lactam antibiotic, cefaclor by liquid chromatography with chemiluminescence detection2003
- Author(s)
  Masaaki Kai(その他5名共著)
- Journal Title
  
  J. Pharm. Biomed. Anal. 30
  
  Pages: 1765-1771
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14102031
[Journal Article] Chromatographic determinations of a β-lactam antibiotic, cefaclor by means of fluorescence, chemiluminescence and mass spectrometry2003
- Author(s)
  Masaaki Kai(その他2名共著)
- Journal Title
  
  Talanta 60
  
  Pages: 325-334
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14102031
[Journal Article] Sensitive determination of a β-lactam antibiotic, cefaclor by liquid chromatography with chemiluminescence detection.2003
- Author(s)
  M.Kai, H.Kinoshita, K.Ohta, S.Hara, M.K.Lee, J.Lu
- Journal Title
  
  J. Pharm. Biomed. Anal. 30
  
  Pages: 1765-1771
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14102031
[Journal Article] Simple chemiluminescence method for determination of mercaptopurine.2002
- Author(s)
  C.Lau, J.Lu, S.Yagisawa, K.Ohta, M.Kai
- Journal Title
  
  Anal. Sci. 18
  
  Pages: 1043-1045
- NAID
  10011311230
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14102031
[Journal Article] Controlled kinetics of non-enzymatic chemiluminescence reactions for simple imaging of DNA and protein.2002
- Author(s)
  C.Lau, J.Lu, T.Yamaguchi, M.Kai
- Journal Title
  
  Anal. Bioanal. Chem. 374
  
  Pages: 1064-1068
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14102031
[Journal Article] Simple and convenient chemiluminescence method for the determination of melatonin2002
- Author(s)
  J.Lu, C.Lau, M.K.Lee, M.Kai
- Journal Title
  
  Anal. Chim. Acta 455
  
  Pages: 193-198
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14102031
[Patent] アミノ酸およびペプチドの検出方法ならびに検出試薬2016
- Inventor(s)
  甲斐雅亮、椛島　力、柴田孝之
- Industrial Property Rights Holder
  長崎大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2016-014936
- Filing Date
  2016-01-28
- Data Source
  KAKENHI-PROJECT-26460146
[Patent] アミノ酸およびペプチドの検出方法ならびに検出試薬2016
- Inventor(s)
  甲斐雅亮、椛島　力、柴田孝之
- Industrial Property Rights Holder
  永崎大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2016-014936
- Filing Date
  2016-01-26
- Data Source
  KAKENHI-PUBLICLY-26116516
[Patent] ペプチドの検出方法2011
- Inventor(s)
  甲斐雅亮、椛島力、柴田孝之
- Industrial Property Rights Holder
  長崎大学
- Industrial Property Number
  2011-045491
- Filing Date
  2011-03-02
- Data Source
  KAKENHI-PROJECT-19209020
[Patent] 2環状シトシン誘導体含有人工二本鎖核酸2011
- Inventor(s)
  甲斐雅亮、柴田孝之、椛島力
- Industrial Property Rights Holder
  長崎大学
- Industrial Property Number
  2011-045485
- Filing Date
  2011-03-02
- Data Source
  KAKENHI-PROJECT-19209020
[Patent] ペプチドの検出方法2011
- Inventor(s)
  甲斐　雅亮
- Industrial Property Rights Holder
  甲斐　雅亮
- Industrial Property Number
  2011-187969
- Filing Date
  2011
- Data Source
  KAKENHI-PROJECT-23659302
[Patent] ペプチドの検出方法2011
- Inventor(s)
  甲斐雅亮, 椛島力, 柴田孝之
- Industrial Property Rights Holder
  長崎大学
- Industrial Property Number
  2011-045491
- Filing Date
  2011-03-02
- Data Source
  KAKENHI-PROJECT-19209020
[Patent] ペプチドの検出方法2011
- Inventor(s)
  甲斐雅亮、椛島力、柴田孝之
- Industrial Property Rights Holder
  甲斐雅亮、椛島力、柴田孝之
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2011-187969
- Filing Date
  2011-08-30
- Data Source
  KAKENHI-PROJECT-23659302
[Patent] 2環状シトシン誘導体含有人工二本鎖核酸2011
- Inventor(s)
  甲斐雅亮, 柴田孝之, 椛島力
- Industrial Property Rights Holder
  長崎大学
- Industrial Property Number
  2011-045485
- Filing Date
  2011-03-02
- Data Source
  KAKENHI-PROJECT-19209020
[Patent] ウラシル特異的な蛍光検出反応及びジヒドロピリミジンデヒドロゲナーゼ欠損症の検査法2010
- Inventor(s)
  甲斐雅亮, 柴田孝之
- Industrial Property Rights Holder
  長崎大学
- Industrial Property Number
  2010-044610
- Filing Date
  2010-03-01
- Data Source
  KAKENHI-PROJECT-19209020
[Patent] ウイルスの識別方法2010
- Inventor(s)
  甲斐雅亮、椛島力
- Industrial Property Rights Holder
  長崎大学
- Filing Date
  2010-03-04
- Data Source
  KAKENHI-PROJECT-19209020
[Patent] ウラシル特異的な蛍光検出反応及びジヒドロピリミジンデヒドロゲナーゼ欠損症の検査法2010
- Inventor(s)
  甲斐雅亮、柴田孝之
- Industrial Property Rights Holder
  長崎大学
- Industrial Property Number
  2010-044610
- Filing Date
  2010-03-01
- Data Source
  KAKENHI-PROJECT-19209020
[Patent] ウイルスの識別方法2010
- Inventor(s)
  甲斐雅亮, 椛島力
- Industrial Property Rights Holder
  長崎大学
- Filing Date
  2010-03-04
- Data Source
  KAKENHI-PROJECT-19209020
[Patent] ウイルスの識別方法2010
- Inventor(s)
  甲斐雅亮、椛島力
- Industrial Property Rights Holder
  長崎大学
- Industrial Property Number
  2010-047640
- Filing Date
  2010-03-04
- Data Source
  KAKENHI-PROJECT-19209020
[Patent] Luminescent polymer and use thereof in bioassay2008
- Inventor(s)
  Masaaki Kai
- Industrial Property Rights Holder
  M. Kai, Daiichi Pure Chemicals
- Acquisition Date
  2008-10-03
- Overseas
- Data Source
  KAKENHI-PROJECT-19209020
[Patent] LUMINESCENT POLYMER AND USE THEREOF IN BIOASSAY2008
- Inventor(s)
  甲斐雅亮
- Industrial Property Rights Holder
  長崎大学
- Filing Date
  2008-10-03
- Overseas
- Data Source
  KAKENHI-PROJECT-19209020
[Patent] Luminescent polymer and use there of in bioassay2008
- Inventor(s)
  甲斐雅亮
- Industrial Property Rights Holder
  長崎大学
- Acquisition Date
  2008-10-03
- Data Source
  KAKENHI-PROJECT-19209020
[Patent] LUMINESCENT POLYMER AND USE THEREOF IN BIOASSAY2002
- Inventor(s)
  MASAAKI KAI
- Industrial Property Rights Holder
  MASAAKI KAI DIICHI KAGAKU YAKUHIN
- Filing Date
  2002-09-19
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14102031
[Presentation] ウラシル特異的蛍光反応を用いた尿中ウラシルの HPLC 定量法2017
- Author(s)
  島村亮祐, 柴田孝之, 根本俊光, 尹晟, 椛島力, 甲斐雅亮
- Organizer
  日本薬学会第137年会
- Place of Presentation
  東北大学（宮城県・仙台市）
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-26460146
[Presentation] 新規蛍光反応によるDNA中のメチル化シトシン定量法の開発2016
- Author(s)
  大島澄佳、柴田孝之、椛島力、甲斐雅亮
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-26460146
[Presentation] 新規蛍光反応を用いたDNA中のシトシン定量法の開発2016
- Author(s)
  大島澄佳, 柴田孝之, 椛島力, 甲斐雅亮
- Organizer
  第33回日本薬学会九州支部大会
- Place of Presentation
  鹿児島大学（鹿児島県・鹿児島市）
- Year and Date
  2016-12-03
- Data Source
  KAKENHI-PROJECT-26460146
[Presentation] 新規蛍光反応によるDNA中のメチル化シトシン定量法の開発2016
- Author(s)
  大島澄佳、柴田孝之、椛島力、甲斐雅亮
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PUBLICLY-26116516
[Presentation] DPD欠損症のスクリーニング検査を指向した尿中ウラシル濃度の蛍光定量法2016
- Author(s)
  柴田孝之, 島村亮祐, 根本俊光, 尹晟, 椛島力, 甲斐雅亮
- Organizer
  日本分析化学会第65年会
- Place of Presentation
  北海道大学（北海道・札幌市）
- Year and Date
  2016-09-14
- Data Source
  KAKENHI-PROJECT-26460146
[Presentation] 簡便かつ高選択的な新規アミノ酸呈色法2016
- Author(s)
  柴田孝之, 椛島力, 廣谷真優, 前田朋樹, 甲斐雅亮
- Organizer
  新アミノ酸分析研究会第6回学術講演会
- Place of Presentation
  東京大学（東京都・文京区）
- Year and Date
  2016-11-04
- Data Source
  KAKENHI-PROJECT-26460146
[Presentation] Collagenase activity and its stimulation in cultured cells by spectrofluorometric evaluation2015
- Author(s)
  Valon Ejupi、Tsutomu Kabashima、Takayuki Shibata、Masaaki Kai
- Organizer
  日本分析化学会第64年会
- Place of Presentation
  九州大学（福岡市）
- Year and Date
  2015-09-09
- Data Source
  KAKENHI-PROJECT-26460146
[Presentation] プリオンタンパク質の加熱処理によるプロテアーゼ抵抗性への影響2015
- Author(s)
  陣内伸俊、椛島力、柴田孝之、甲斐雅亮
- Organizer
  第32回日本薬学会九州支部大会
- Place of Presentation
  九州保健福祉大学（延岡市）
- Year and Date
  2015-11-28
- Data Source
  KAKENHI-PROJECT-26460146
[Presentation] ペプチドの新規蛍光検出反応およびHPLCによるヒストン修飾部位の解析2015
- Author(s)
  柴田孝之、田上奈緒美、椛島力、甲斐雅亮
- Organizer
  新アミノ酸分析研究会第5回学術講演会
- Place of Presentation
  東京大学（東京）
- Year and Date
  2015-12-07
- Data Source
  KAKENHI-PUBLICLY-26116516
[Presentation] 新規蛍光反応によるヒストン修飾解析法の開発2015
- Author(s)
  田上奈緒美、椛島力、柴田孝之、甲斐雅亮
- Organizer
  第32回日本薬学会九州支部大会
- Place of Presentation
  九州保健福祉大学（延岡市）
- Year and Date
  2015-11-28
- Data Source
  KAKENHI-PROJECT-26460146
[Presentation] Fluorometric assay of dihydroorotate dehydrogenase activity and orotic acid concentration in a cell lysate2015
- Author(s)
  Sheng Yin、Tsutomu Kabashima、Takayuki Shibata、Masaaki Kai
- Organizer
  日本分析化学会第64年会
- Place of Presentation
  九州大学（福岡市）
- Year and Date
  2015-09-09
- Data Source
  KAKENHI-PROJECT-26460146
[Presentation] Fluorometric assay of dihydroorotate dehydrogenase activity and orotic acid concentration in a cell lysate2015
- Author(s)
  Sheng Yin、Tsutomu Kabashima、Takayuki Shibata、Masaaki Kai
- Organizer
  日本分析化学会第64年会
- Place of Presentation
  九州大学（福岡市）
- Year and Date
  2015-09-09
- Data Source
  KAKENHI-PUBLICLY-26116516
[Presentation] Collagenase activity and its stimulation in cultured cells by spectrofluorometric evaluation2015
- Author(s)
  Valon Ejupi、Tsutomu Kabashima、Takayuki Shibata、Masaaki Kai
- Organizer
  日本分析化学会第64年会
- Place of Presentation
  九州大学（福岡市）
- Year and Date
  2015-09-09
- Data Source
  KAKENHI-PUBLICLY-26116516
[Presentation] DNAアプタマー-siRNAによるHIVプロテアーゼの発現抑制効果2015
- Author(s)
  安達杏奈、朱欽昌、椛島力、柴田孝之、甲斐雅亮
- Organizer
  第28回バイオメディカル分析科学シンポジウム（BMAS2015）
- Place of Presentation
  長崎大学（長崎市）
- Year and Date
  2015-08-21
- Data Source
  KAKENHI-PUBLICLY-26116516
[Presentation] Platforms of luminescence in analytical chemistry for nucleic acids2015
- Author(s)
  Jianzhong Lu、Masaaki Kai
- Organizer
  日本分析化学会第64年会
- Place of Presentation
  九州大学（福岡市）
- Year and Date
  2015-09-11
- Invited
- Data Source
  KAKENHI-PUBLICLY-26116516
[Presentation] ペプチドの新規蛍光検出反応およびHPLCによるヒストン修飾部位の解析2015
- Author(s)
  柴田孝之、田上奈緒美、椛島力、甲斐雅亮
- Organizer
  新アミノ酸分析研究会第5回学術講演会
- Place of Presentation
  東京大学（東京）
- Year and Date
  2015-12-07
- Data Source
  KAKENHI-PROJECT-26460146
[Presentation] DNA アプタマーの HER2 発現細胞への導入2015
- Author(s)
  安達杏奈、椛島力、柴田孝之、甲斐雅亮
- Organizer
  第32回日本薬学会九州支部大会
- Place of Presentation
  九州保健福祉大学（延岡市）
- Year and Date
  2015-11-28
- Data Source
  KAKENHI-PUBLICLY-26116516
[Presentation] 新規蛍光反応によるヒストン修飾解析法の開発2015
- Author(s)
  田上奈緒美、椛島力、柴田孝之、甲斐雅亮
- Organizer
  第32回日本薬学会九州支部大会
- Place of Presentation
  九州保健福祉大学（延岡市）
- Year and Date
  2015-11-28
- Data Source
  KAKENHI-PUBLICLY-26116516
[Presentation] DNA アプタマーのHER2発現細胞への導入2015
- Author(s)
  安達杏奈、椛島力、柴田孝之、甲斐雅亮
- Organizer
  第32回日本薬学会九州支部大会
- Place of Presentation
  九州保健福祉大学（延岡市）
- Year and Date
  2015-11-28
- Data Source
  KAKENHI-PROJECT-26460146
[Presentation] DNAアプタマー-siRNAによるHIVプロテアーゼの発現抑制効果2015
- Author(s)
  安達杏奈、朱欽昌、椛島力、柴田孝之、甲斐雅亮
- Organizer
  第28回バイオメディカル分析科学シンポジウム（BMAS2015）
- Place of Presentation
  長崎大学（長崎市）
- Year and Date
  2015-08-21
- Data Source
  KAKENHI-PROJECT-26460146
[Presentation] プリオンタンパク質の加熱処理によるプロテアーゼ抵抗性への影響2015
- Author(s)
  陣内伸俊、椛島力、柴田孝之、甲斐雅亮
- Organizer
  第32回日本薬学会九州支部大会
- Place of Presentation
  九州保健福祉大学（延岡市）
- Year and Date
  2015-11-28
- Data Source
  KAKENHI-PUBLICLY-26116516
[Presentation] タンパク質及び核酸の蛍光・化学発光検出法の開発と病態診断への応用2013
- Author(s)
  甲斐雅亮
- Organizer
  2013年度日本分析化学会九州支部講演会
- Place of Presentation
  九州大学
- Year and Date
  2013-11-08
- Data Source
  KAKENHI-PROJECT-23659302
[Presentation] Highly selective and sensitive method for the determination of collagen in mammalian tissue by a novel fluorescence reaction2012
- Author(s)
  Masaaki Kai
- Organizer
  The 6th Shanghai international symposium on analytical chemistry
- Place of Presentation
  上海市
- Data Source
  KAKENHI-PROJECT-23659302
[Presentation] Highly selective and sensitive method for the determination of collagen in mammalian tissue by a novel fluorescence reaction2012
- Author(s)
  Masaaki Kai
- Organizer
  The 6th Shanghai international symposium on analytical chemistry
- Place of Presentation
  中国　上海市
- Invited
- Data Source
  KAKENHI-PROJECT-23659302
[Presentation] New tools for the research on HIV and prion diseases2009
- Author(s)
  Masaaki Kai
- Organizer
  The second Asia symposium on pharmaceutical sciences in Nagasaki
- Place of Presentation
  Nagasaki
- Data Source
  KAKENHI-PROJECT-19209020
[Presentation] New tools for the research on HIV and prion diseases2009
- Author(s)
  Masaaki Kai
- Organizer
  The second Asia symposium on pharmaceutical sciences in Nagasaki
- Place of Presentation
  長崎市
- Data Source
  KAKENHI-PROJECT-19209020
[Presentation] ペプチドに特異的な蛍光反応を用いたHIV/HCV 識別法の開発
- Author(s)
  川島歌織、椛島力、柴田孝之、甲斐雅亮
- Organizer
  第31回日本薬学会九州支部大会
- Place of Presentation
  第一薬科大学（福岡市）
- Year and Date
  2014-12-06 – 2014-12-07
- Data Source
  KAKENHI-PROJECT-26460146
[Presentation] Dihydroorotate dehydrogenase assay using a specific fluorescence reaction
- Author(s)
  尹晟、椛島力、柴田孝之、甲斐雅亮
- Organizer
  日本分析化学会第63年会
- Place of Presentation
  広島大学（東広島市）
- Year and Date
  2014-09-17 – 2014-09-19
- Data Source
  KAKENHI-PROJECT-26460146
[Presentation] Dihydroorotate dehydrogenase assay using a specific fluorescence reaction
- Author(s)
  尹晟、椛島力、柴田孝之、甲斐雅亮
- Organizer
  日本分析化学会第63年会
- Place of Presentation
  広島大学（東広島市）
- Year and Date
  2014-09-17 – 2014-09-19
- Data Source
  KAKENHI-PUBLICLY-26116516
[Presentation] Assay of collagenase activity in human cells using a novel fluorescence reaction
- Author(s)
  Valon Ejupi、椛島力、柴田孝之、甲斐雅亮
- Organizer
  日本分析化学会第63年会
- Place of Presentation
  広島大学（東広島市）
- Year and Date
  2014-09-17 – 2014-09-19
- Data Source
  KAKENHI-PROJECT-26460146
[Presentation] 3,4-DHPAA を用いた新規プロリダーゼ活性測定法の開発
- Author(s)
  曽宮実和子、椛島力、柴田孝之、甲斐雅亮
- Organizer
  第31回日本薬学会九州支部大会
- Place of Presentation
  第一薬科大学（福岡市）
- Year and Date
  2014-12-06 – 2014-12-07
- Data Source
  KAKENHI-PUBLICLY-26116516
[Presentation] 3,4-DHPAA蛍光反応の新規プロリダーゼ活性測定法への応用
- Author(s)
  椛島力、曽宮実和子、柴田孝之、甲斐雅亮
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸サンボーホール（神戸市）
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PUBLICLY-26116516
[Presentation] Assay of collagenase activity in human cells using a novel fluorescence reaction
- Author(s)
  Valon Ejupi、椛島力、柴田孝之、甲斐雅亮
- Organizer
  日本分析化学会第63年会
- Place of Presentation
  広島大学（東広島市）
- Year and Date
  2014-09-17 – 2014-09-19
- Data Source
  KAKENHI-PUBLICLY-26116516
[Presentation] タンパク質及び核酸の蛍光・化学発光検出法の開発と病態診断への応用
- Author(s)
  甲斐雅亮
- Organizer
  2013年度日本分析化学会九州支部講演会
- Place of Presentation
  九州大学（春日市）
- Invited
- Data Source
  KAKENHI-PROJECT-23659302
[Presentation] 3,4-DHPAA蛍光反応の新規プロリダーゼ活性測定法への応用
- Author(s)
  椛島力、曽宮実和子、柴田孝之、甲斐雅亮
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸サンボーホール（神戸市）
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26460146
[Presentation] ペプチドに特異的な蛍光反応を用いたHIV/HCV 識別法の開発
- Author(s)
  川島歌織、椛島力、柴田孝之、甲斐雅亮
- Organizer
  第31回日本薬学会九州支部大会
- Place of Presentation
  第一薬科大学（福岡市）
- Year and Date
  2014-12-06 – 2014-12-07
- Data Source
  KAKENHI-PUBLICLY-26116516
[Presentation] 3,4-DHPAA を用いた新規プロリダーゼ活性測定法の開発
- Author(s)
  曽宮実和子、椛島力、柴田孝之、甲斐雅亮
- Organizer
  第31回日本薬学会九州支部大会
- Place of Presentation
  第一薬科大学（福岡市）
- Year and Date
  2014-12-06 – 2014-12-07
- Data Source
  KAKENHI-PROJECT-26460146

1. KABASHIMA Tsutomu (20274673)

# of Collaborated Projects: 7 results

# of Collaborated Products: 45 results
2. SHIBATA takayuki (10448491)

# of Collaborated Projects: 4 results

# of Collaborated Products: 34 results
3. OHTA Kazuko (20039647)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
4. SHIMAMURA Ryosuke

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. OOSHIMA Sumika

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. ADACHI Anna

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. JINNOUCHI Nobutoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. TANOUE Naomi

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. KAWASHIMA Kaori

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. SOMIYA Miwako

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. YIN Sheng

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
12. Ejupi Valon

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

KAI Masaaki 甲斐 雅亮

Research Projects

Research Products

Co-Researchers

新規エピゲノム分析によるクロマチン変異の解析Principal Investigator

Principal Investigator

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Development of the anti-AIDS drug using aptamer-siRNA

Principal Investigator

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Development of the discrimination method for mutation and drug resistance of an AIDS virusPrincipal Investigator

Principal Investigator

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Development of a novel detection method for abnormal prion proteinPrincipal Investigator

Principal Investigator

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プロテインチップに用いる新しい蛍光検出反応の開発Principal Investigator

Principal Investigator

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新規高分子発光プローブによる発現遺伝子の超高感度マイクロアレー解析Principal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

新規高分子発光プローブによるmRNAのマイクロアレー解析Principal Investigator

Principal Investigator

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Review Section

Research Institution

超高感度化学発光検出によるmRNAのマイクロアレー解析Principal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

核酸検出に用いる新規水溶性化学発光高分子プローブの創製Principal Investigator

Principal Investigator

Project Period (FY)

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Development of Super-Sensitive Technique for the Detection of Nucleic Acids with Luminescent ReagentPrincipal Investigator

Principal Investigator

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アミノ酸配列決定に用いる新規化学発光ラベル化試薬の開発Principal Investigator

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Inquiry of trace amount of bioactive unknown peptides by specific chemiluminescent derivatization detectionPrincipal Investigator

Principal Investigator

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Development of a chemiluminescent reagent that recognizes guanine in nucleic acid, and its use for chemiluminescence detection of DNAPrincipal Investigator

Principal Investigator

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KAI Masaaki 甲斐雅亮

[Book] 薬学物理化学演習　[第３版]（第５章　電解質溶液）2011

[Book] 改定６版分析化学便覧　（第２章　2.1.3有機定性分析）2011

[Book] 薬学物理化学演習 [第3版](第5章電解質溶液)2011

[Book] 薬学物理化学[第5版](第5章電解質溶液pp79-98)2010

[Book] ベーシック分析化学 (第16章タンパク質と核酸の標識)2006

[Book] ベーシック分析化学 (第16章タンパク質と核酸の標識)2006

[Book] 薬学物理化学 -第4版- (第7章界面とコロイド)(松島美一,吉柳節夫監修)2004

[Book] 薬理物理化学-第4版-(第7章界面とコロイド)(松島美一, 吉柳節夫監修)2004