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SAKATA Nobuo  坂田 宣夫

Researcher Number 00170598
Other IDs
  • ORCIDhttps://orcid.org/0000-0001-9967-8409
Affiliation (based on the past Project Information) *help 2013 – 2014: 昭和薬科大学, 薬学部, 講師
2002 – 2003: 昭和薬科大学, 薬学部, 講師
Review Section/Research Field
Principal Investigator
Experimental pathology / Pathological medical chemistry
Keywords
Principal Investigator
ZFH4 / ATBF1 / Central nervous System / Zinc Finger / Homeodomain / 中枢神経 / ジンクフィンガー / ホメオドメイン / スプライソソーム / シグナル伝達研究の新展開 … More / JMJD6 / LUC7L3 / Smad / Alternative splicing Less
  • Research Projects

    (2 results)
  • Research Products

    (10 results)
  • Co-Researchers

    (5 People)
  •  Smad-mediated spliceosome assembly and alternative splicingPrincipal Investigator

    • Principal Investigator
      SAKATA Nobuo
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Showa Pharmaceutical University
  •  EXPRESSION ANALYSIS OF TRANSCRIPTION FACTOR, ATBF1 AND ZFH4 IN NORMAL DEVELOPING RAT BRAINPrincipal Investigator

    • Principal Investigator
      SAKATA Nobuo, 川口 誠
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      SHOWA PHARMACEUTICAL UNIVERSITY
      Toyama Medical and Pharmaceutical University

All 2014 2013 Other

All Journal Article Presentation

  • [Journal Article] TGF-β signaling cooperates with AT motif-binding factor-1 for repression of the α-fetoprotein promoter.2014

    • Author(s)
      Nobuo Sakata, Satoshi Kaneko, Souichi Ikeno, Yutaka Miura, Hidekazu Nakabayashi, Xue-Yuan Dong, Jin-Tang Dong, Taiki Tamaki, Naoko Nakano, Susumu Itoh
    • Journal Title

      J. Signal Transduct.

      Volume: 2014 Pages: 970346-970346

    • DOI

      10.1155/2014/970346

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25670168, KAKENHI-PROJECT-26305006
  • [Journal Article] C18ORF1: A Novel Negative Regulator of TGF-β Signaling.2014

    • Author(s)
      2. Nakano N, Maeyama K, Ikeno S, Itoh F, Togawa Y, Katsu Y, Thanh Thao, VN, Watanabe Y, Kato M & Itoh, S.
    • Journal Title

      J. Biol. Chem.,

      Volume: 289 Issue: 18 Pages: 12680-12680

    • DOI

      10.1074/jbc.m114.558981

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23689023, KAKENHI-PUBLICLY-25118728, KAKENHI-PROJECT-25293092, KAKENHI-PROJECT-25670168, KAKENHI-PROJECT-26305006, KAKENHI-PROJECT-26460479
  • [Journal Article] ZFHX4 interacts with the NuRD core member CHD4 and regulates the glioblastoma tumor initiating cell state.2013

    • Author(s)
      Chudnovsky Y, Kim D, Zheng S, Whyte WA, Bansal M, Bray M, Gopal S, Theisen MA, Bilodeau S, Thiru P, Muffat J, Yilmaz OH, Mitalipova M, Woolard K, Lee J, Nishimura R, Sakata N, Fine HA, Carpenter AE, Silver SJ, Verhaak RGW, Califano A, Young RA, Ligon KL, Mellinghoff IK, Root DE, Sabatini DM, Hahn WC, Chheda MG
    • Journal Title

      Cell Reports

      Volume: 6 Issue: 2 Pages: 1-12

    • DOI

      10.1016/j.celrep.2013.12.032

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659824, KAKENHI-PROJECT-25293378, KAKENHI-PROJECT-25670168
  • [Presentation] 転写因子ATBF1とTGF-βシグナル伝達系によるalpha-fetoprotein遺伝子プロモーターの協調的抑制2014

    • Author(s)
      坂田宣夫、金子哲士、池野聡一、三浦裕、中林秀和、Xue-Yuan Dong、Jin-Tang Dong、玉置大器、中野なおこ、伊東進
    • Organizer
      第58回日本薬学会関東支部会
    • Place of Presentation
      昭和薬科大学(町田市)
    • Year and Date
      2014-10-04
    • Data Source
      KAKENHI-PROJECT-25670168
  • [Presentation] TMEPAIファミリーによるTGF-βシグナル制御機構2014

    • Author(s)
      中野なおこ、赤津俊介、中田美紀、伊東史子、坂田宣夫、葛祐紀、池野聡一、戸川陽子、伊東進
    • Organizer
      第58回日本薬学会関東支部会
    • Place of Presentation
      昭和薬科大学(町田市)
    • Year and Date
      2014-10-04
    • Data Source
      KAKENHI-PROJECT-25670168
  • [Presentation] Transcriptional Repression Mechanisms of TGF-β Signaling and ATBF1 on the AFP Promoter

    • Author(s)
      Nobuo Sakata, Satoshi Kaneko, Souichi Ikeno, Yutaka Miura, Hidekazu Nakabayashi, Xue-Yuan Dong, Jin-Tang Dong, Taiki Tamaki, Naoko Nakano, Susumu Itoh
    • Organizer
      Joint International Symposium on TGF-β Family and Cancer “Signal Network in Tumor Microenvironment”
    • Place of Presentation
      つくば国際会議場(つくば市)
    • Year and Date
      2015-01-12 – 2015-01-13
    • Data Source
      KAKENHI-PROJECT-25670168
  • [Presentation] TGF-β Signaling Cooperates with AT Motif Binding Factor 1 (ATBF1) to Repress α-Fetoprotein Gene in Human Hepatoma Cells.

    • Author(s)
      Nobuo Sakata, Satoshi Kaneko, Souichi Ikeno, Yutaka Miura, Hidekazu Nakabayashi, Taiki Tamaki, Naoko Nakano, Susumu Itoh
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Data Source
      KAKENHI-PROJECT-25670168
  • [Presentation] Negative regulation of α-fetoprotein gene transcription by TGF-β signaling with AT motif binding factor 1 (ATBF1)

    • Author(s)
      Nobuo Sakata, Satoshi Kaneko, Souichi Ikeno, Yutaka Miura, Hidekazu Nakabayashi, Xue-Yuan Dong, Jin-Tang Dong, Taiki Tamaki, Naoko Nakano, Susumu Itoh
    • Organizer
      TGF-β Meeting in Leiden 2014 “TGF-β signal transduction in human disease”
    • Place of Presentation
      Leiden Univ. Med. Center (Leiden, NL)
    • Year and Date
      2014-05-07 – 2014-05-10
    • Data Source
      KAKENHI-PROJECT-25670168
  • [Presentation] 2.TGF-β signaling cooperate with ATBF1 in AFP transcription

    • Author(s)
      Nobuo Sakata, Satoshi Kaneko, Souichi Ikeno, Yutaka Miura, Hidekazu Nakabayashi, Xue-Yuan Dong, Jin-Tang Dong, Taiki Tamaki, Naoko Nakano, Susumu Itoh
    • Organizer
      The 3rd International Symposium by JSPS Core-to-Core Program “Cooperative International Framework in TGF-β Family Signaling”
    • Place of Presentation
      大和屋本店(松山市)
    • Data Source
      KAKENHI-PROJECT-25670168
  • [Presentation] TGF-β/Smadシグナル伝達系と転写因子ATBF1によるα-fetoprotein遺伝子転写抑制

    • Author(s)
      坂田宣夫、金子哲士、池野聡一、三浦裕、中林秀和、Xue-Yuan Dong、Jin-Tang Dong、玉置大器、中野なおこ、伊東進
    • Organizer
      第36回日本分子生物学会年会
    • Place of Presentation
      神戸国際会議場(神戸市)
    • Data Source
      KAKENHI-PROJECT-25670168
  • 1.  ITOH Susumu (70223154)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 2.  SASAHARA Masakiyo (20154015)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  川口 誠 (50204699)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  西村 理行
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 5.  伊東 史子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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