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SASAKI Hitoshi  佐々木 均

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… Alternative Names

佐々木 均  ササキ ヒトシ

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Researcher Number 00170689
Other IDs
Affiliation (Current) 2020: 長崎大学, 病院(医学系), 教授
Affiliation (based on the past Project Information) *help 2014 – 2020: 長崎大学, 病院(医学系), 教授
2011 – 2014: 長崎大学, 大学病院, 教授
2009 – 2011: Nagasaki University, 病院, 教授
2010: 長崎大学, 長崎大学病院・薬剤部, 教授
2003 – 2008: 長崎大学, 医学部・歯学部附属病院, 教授 … More
2000: Department of Hospital Pharmacy Nagasaki University School of Medicine Professor, 医学部・附属病院, 教授
1998 – 1999: 長崎大学, 医学部・附属病院, 助教授
1997: 長崎大学, 医学部附属病院, 助教授
1994: 長崎大学, 薬学部, 助教授 Less
Review Section/Research Field
Principal Investigator
Medical pharmacy / Physical pharmacy / Ophthalmology / 医薬分子機能学 / Basic Section 47060:Clinical pharmacy-related
Except Principal Investigator
Medical pharmacy / Physical pharmacy / Radiation science / Collagenous pathology/Allergology / Surgical dentistry / Basic Section 90120:Biomaterials-related
Keywords
Principal Investigator
遺伝子デリバリー / 遺伝子 / 遺伝子治療 / ドラッグデリバリー / Drug delivery system / γ-polyglutamic acid / 眼 / 薬物送達 / 速度論 / デリバリー … More / 疾病 / 肝臓 / カチオン性高分子 / 肝炎 / 肝切除 / カチオン性リポソーム / ウイルス性肝炎モデル / 薬剤性肝炎モデル / ガラクトサミン / 遣伝子 / 遣伝子治療 / 癌 / ナノ材料 / 葉酸 / グリチルリチン / 生体適合型ベクター / 生体分解型ベクター / 自己組織化 / 遺伝子導入技術 / 静電的相互作用 / 低分子リガンド / カチオン性遺伝子ベクター / ナノ微粒子 / 遺伝子導入 / アニオン性高分子 / chondroitin sulfate / 加齢黄斑変性症 / 遺伝子ベクター / 顧みられない熱帯病 / マラリア / 住血吸虫症 / シャーガス病 / DNAワクチン / 感染症 / 核酸 / ナノデバイス / 薬物治療 / 膜透過 / 拡散 / 薬物動態 / 適正化 / EYE / DRUG DELIVERY / PHARMACOTHERAPY / MEMBRANE PENETRATION / PHARMACOKINETICS / DIFFUSION / DRUG DISPOSITION / ADEQUATE MEDICATION-USE / 局所適用 / リポソーム / 高分子 / 眼科 / 薬物速度論 / 臨床応用 / 局所 / 動態 / ベクター / Topical application / Gene delivery / Liposomes / Polymer / Ophthalmology / Pharmacokinetics / Clinical application / 核酸医薬 / ドラッグデリバリーシステム … More
Except Principal Investigator
薬物送達 / 後発医薬品 / CMC / 腸内細菌 / 代謝 / プロドラッグ / サリチル酸 / アミノ酸抱合体 / 医薬品情報 / 安全性学 / 品質試験 / 毒性試験 / 薬剤応答性 / セロミクス / 動物実験 / 薬剤仮応性 / 薬剤反応性 / 薬学 / 放射線 / ナノバイオ / イメージング / ワクチン / ナノ材料 / 癌 / 感染症 / DNAワクチン / ナノデバイス / マラリア / 遺伝子デリバリー / メラノーマ / 肝臓 / 肝臓表面投与 / phenol red / ラット / DDS / 粘性製剤 / 単回投与 / 微量連続投与 / Liver / Drug targeting / Liver surface application / Phenol red / Rat / Drug delivery system / Viscous dosage form / 関節リウマチ / CTLA-4-Ig / バイオマーカー / 単球 / M1・M2 / 破骨細胞 / 骨破壊 / ACPA / サイトカイン・ケモカイン / 滑膜線維芽細胞 / ACPA-サブクラス / CTLA-4Ig / リバースシグナル / アレイ解析 / 関節超音波 / 遺伝子活性化基質 / 遺伝子導入担体 / 骨再生 / 遺伝子送達デバイス / 自己組織化デバイス / 薬剤性肝障害 / ヒト肝キメラマウス / ファーマコビジランス / 製剤品質評価 / トキシコゲノミクス / T-LEX / T-LEX / 肝線維症 / 核酸医薬品 / siRNA Less
  • Research Projects

    (16 results)
  • Research Products

    (148 results)
  • Co-Researchers

    (37 People)
  •  肝指向型三元複合体を用いたsiRNA導入による肝線維症の新規治療法の開発Ongoing

    • Principal Investigator
      黒崎 友亮
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 90120:Biomaterials-related
    • Research Institution
      Nagasaki University
  •  難治性呼吸器疾患に対する新規核酸医薬品の開発Principal InvestigatorOngoing

    • Principal Investigator
      佐々木 均
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 47060:Clinical pharmacy-related
    • Research Institution
      Nagasaki University
  •  Gene activated-matrix comprised of self-assemble and multi-functional nano-devise facilitates the bone engineeringOngoing

    • Principal Investigator
      朝比奈 泉
    • Project Period (FY)
      2017 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Surgical dentistry
    • Research Institution
      Nagasaki University
  •  Basic research for searching of new therapeutic targets of rheumatoid arthritis through investigation of novel action of CTLA-4-Ig

    • Principal Investigator
      KAWAKAMI Atsushi
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Collagenous pathology/Allergology
    • Research Institution
      Nagasaki University
  •  Development of the novel technique intended to the prophylaxis and treatment of neglected tropical diseasesPrincipal Investigator

    • Principal Investigator
      SASAKI Hitoshi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Medical pharmacy
    • Research Institution
      Nagasaki University
  •  Study of risk assessment of drug-induced liver injury using chimeric mice with highly humanized liver and large-scale adverse drug reactions databese

    • Principal Investigator
      NAKASHIMA Mikiro
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      Nagasaki University
  •  Development of self-assembling nanodevices for multimodal molecular imaging

    • Principal Investigator
      MUKAI Takahiro
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Radiation science
    • Research Institution
      Kobe Pharmaceutical University
  •  Development of safety vaccine using spleen- and dendritice cells-targeted nano device

    • Principal Investigator
      KITAHARA Takashi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      Nagasaki University
  •  Development of novel gene therapy targeting age-related macular degenerationPrincipal Investigator

    • Principal Investigator
      SASAKI Hitoshi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Ophthalmology
    • Research Institution
      Nagasaki University
  •  The development of self-assembly nano-devices based on electrostatic interaction and the application to selective drug deliveryPrincipal Investigator

    • Principal Investigator
      SASAKI Hitoshi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Physical pharmacy
    • Research Institution
      Nagasaki University
  •  Study on evaluation system for drug cardiotoxicity using on-chip cell-besed analysis and quality examination of generic products of injection

    • Principal Investigator
      NAKASHIMA Mikiro
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      Nagasaki University
  •  Influence of disease stage and pharmacotherapy on gene deliveryPrincipal Investigator

    • Principal Investigator
      SASAKI Hitoshi
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      Nagasaki University
  •  Development of topical gene delivery system for clinical applicationPrincipal Investigator

    • Principal Investigator
      SASAKI Hitoshi
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      Nagasaki University Hospital of Medicine and Dentistry
  •  Development of dosage form for the application to the liver surface for targeting of drug in the liver

    • Principal Investigator
      NAKAMURA Junzo
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Physical pharmacy
    • Research Institution
      Nagasaki University
  •  PHARMACOKINETIC ANALYSIS FOR ADEQUATE MEDICATION-USE IN OPHTHALMOLOGYPrincipal Investigator

    • Principal Investigator
      SASAKI Hitoshi
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      医薬分子機能学
    • Research Institution
      NAGASAKI UNIVERSITY HOSPITAL, SCHOOL OF MEDICINE
  •  腸内細菌による代謝を利用した大腸への選択的薬物送達に関する研究

    • Principal Investigator
      NAKAMURA Junzo
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Physical pharmacy
    • Research Institution
      Nagasaki University

All 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation Patent

  • [Journal Article] Splenic Delivery System of pDNA through Complexes Electrostatically Constructed with Protamine and Chondroitin Sulfate2019

    • Author(s)
      Kodama Y, Nishigaki W, Nakamura T, Fumoto S, Nishida K, Kurosaki T, Nakagawa H, Kitahara T, Muro T, Sasaki H.
    • Journal Title

      Biol. Pharm. Bull.

      Volume: 41 Issue: 3 Pages: 342-349

    • DOI

      10.1248/bpb.b17-00667

    • NAID

      130006407447

    • ISSN
      0918-6158, 1347-5215
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H02589
  • [Journal Article] Methotrexate-Coated Complexes of Plasmid DNA and Polyethylenimine for Gene Delivery2019

    • Author(s)
      Kodama Y, Nishigaki W, Nakamura T, Fumoto S, Nishida K, Kurosaki T, Nakagawa H, Kitahara T, Muro T, Sasaki H.
    • Journal Title

      Biol. Pharm. Bull.

      Volume: 41 Issue: 10 Pages: 1537-1542

    • DOI

      10.1248/bpb.b18-00144

    • NAID

      130007494219

    • ISSN
      0918-6158, 1347-5215
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08449, KAKENHI-PROJECT-18H02589
  • [Journal Article] Gene delivery system of pDNA using the blood glycoprotein fetuin.2018

    • Author(s)
      Kodama Y, Hanamura H, Muro T, Nakagawa H, Kurosaki T, Nakamura T, Kitahara T, Kawakami S, Nakashima M, Sasaki H.
    • Journal Title

      Journal of Drug Targeting

      Volume: 印刷中 Pages: 604-609

    • DOI

      10.1080/1061186x.2017.1405425

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08449, KAKENHI-PROJECT-18H02589
  • [Journal Article] Application of biodegradable dendrigraft poly-L-lysine to a small interfering RNA delivery system.2017

    • Author(s)
      Kodama Y, Kuramoto H, Mieda Y, Muro T, Nakagawa H, Kurosaki T, Sakaguchi M, Nakamura T, Kitahara T, Sasaki H.
    • Journal Title

      Journal of Drug Targeting

      Volume: 25 Pages: 49-57

    • DOI

      10.1080/1061186x.2016.1184670

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26293034, KAKENHI-PROJECT-26860107, KAKENHI-PROJECT-15K08444
  • [Journal Article] Secure and effective gene delivery system of plasmid DNA coated by polynucleotide.2015

    • Author(s)
      Kodama Y, Ohkubo C, Kurosaki T, Egashira K, Sato K, Fumoto S, Nishida K, Higuchi N, Kitahara T, Nakamura T, Sasaki H.
    • Journal Title

      J Drug Target

      Volume: 23 Pages: 43-51

    • DOI

      10.3109/1061186x.2014.950665

    • NAID

      120005527920

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24590198, KAKENHI-PROJECT-25350553, KAKENHI-PROJECT-26293034, KAKENHI-PROJECT-26860107
  • [Journal Article] Immunigenicity and anti-fecundity effect of nano particle coated glutathione-S-transferase (SjGST) DNA vaccine against murine Schistosoma japonicum infection.2015

    • Author(s)
      Mbanefo EC, Kumagai T, Kodama Y, Kurosaki T, Furushima-Shimogawara R, Cherif MS, Mizukami S, Kikuchi M, Huy NT, Ohta N, Sasaki H, Hirayama K.
    • Journal Title

      Parasitology International

      Volume: 64 Pages: 24-31

    • DOI

      10.1016/j.parint.2015.01.005

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24590503, KAKENHI-PROJECT-26293034, KAKENHI-PROJECT-26860107, KAKENHI-PROJECT-15K08445, KAKENHI-PROJECT-15H05278, KAKENHI-PROJECT-26670198, KAKENHI-PROJECT-25293099
  • [Journal Article] Quaternary complexes modified from pDNA and poly-l-lysine complexes to enhance pH-buffering effect and suppress cytotoxicity.2015

    • Author(s)
      Kodama Y, Yatsugi Y, Kitahara T, Kurosaki T, Egashira K, Nakashima M, Muro T, Nakagawa H, Higuchi N, Nakamura T, Sasaki H.
    • Journal Title

      Journal of Pharmaceutical Sciences

      Volume: 104 Pages: 1470-1477

    • DOI

      10.1002/jps.24364

    • NAID

      120005600828

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26860107, KAKENHI-PROJECT-26293034
  • [Journal Article] Splenic gene delivery system using self-assembling nano-complex with phosphatidylserine analog.2015

    • Author(s)
      Kurosaki T, Nakasone C, Kodama Y, Egashira K, Harasawa H, Muro T, Nakagawa H, Kitahara T, Higuchi N, Nakamura T, Sasaki H.
    • Journal Title

      Biol Pharm Bull.

      Volume: 38 Pages: 23-29

    • NAID

      130004872233

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26293034
  • [Journal Article] Splenic gene delivery system using self-assembling nano-complex with phosphatidylserine analog.2015

    • Author(s)
      Kurosaki T, Nakasone C, Kodama Y, Egashira K, Harasawa H, Muro T, Nakagawa H, Kitahara T, Higuchi N, Nakamura T, Sasaki H.
    • Journal Title

      Biol Pharm Bull.

      Volume: 38 Pages: 23-29

    • NAID

      130004872233

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24590198
  • [Journal Article] Radiolabeled γ-polyglutamic acid complex as a nano-platform for sentinel lymph node imaging2014

    • Author(s)
      Kohei Sano, Yuriko Iwamiya, Tomoaki Kurosaki, Mikako Ogawa, Yasuhiro Magata, Hitoshi Sasaki, Takashi Ohshim, Minoru Maeda, Takahiro Mukai
    • Journal Title

      Journal of Controlled Release

      Volume: 194 Pages: 310-315

    • DOI

      10.1016/j.jconrel.2014.08.025

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24390294
  • [Journal Article] Novel siRNA delivery system using a ternary polymer complex with strong silencing effect and no cytotoxicity.2014

    • Author(s)
      Kodama Y, Shiokawa Y, Nakamura T, Kurosaki T, Aki K, Nakagawa H, Muro T, Kitahara T, Higuchi N, Sasaki H.
    • Journal Title

      Biol Pharm Bull

      Volume: 37 Pages: 1274-1281

    • NAID

      130004677533

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24590198
  • [Journal Article] Biodegradable nanoparticles composed of dendrigraft poly-L-lysine for gene delivery.2014

    • Author(s)
      Kodama Y, Nakamura T, Kurosaki T, Egashira K, Mine T, Nakagawa H, Muro T, Kitahara T, Higuchi N, Sasaki H.
    • Journal Title

      Eur J Pharm Biopharm.

      Volume: 87 Pages: 472-476

    • DOI

      10.1016/j.ejpb.2014.04.013

    • NAID

      120005522359

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24590198, KAKENHI-PROJECT-26293034, KAKENHI-PROJECT-26860107
  • [Journal Article] Novel siRNA delivery system using a ternary polymer complex with strong silencing effect and no cytotoxicity.2014

    • Author(s)
      Kodama Y, Shiokawa Y, Nakamura T, Kurosaki T, Aki K, Nakagawa H, Muro T, Kitahara T, Higuchi N, Sasaki H.
    • Journal Title

      Biol Pharm Bull.

      Volume: 37 Pages: 1274-1281

    • NAID

      130004677533

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26293034
  • [Journal Article] Ocular Gene Delivery Systems Using Ternary Complexes of Plasmid DNA, Polyethylenimine, and Anionic Polymers2013

    • Author(s)
      Kurosaki T, Uematsu M, Shimoda K, Suzuma K, Nakai M, Nakamura T, Kitahara T, Kitaoka T, Sasaki H.
    • Journal Title

      Biol. Pharm. Bull.

      Volume: 36 Issue: 1 Pages: 96-101

    • DOI

      10.1248/bpb.b12-00728

    • NAID

      130003361352

    • ISSN
      0918-6158, 1347-5215
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659813
  • [Journal Article] Ternary complex of plasmid DNA with protamine and γ-polyglutamic acid for biocompatible gene delivery system2013

    • Author(s)
      Kanda K, Kodama Y, Kurosaki T, Imamura M, Nakagawa H, Muro T, Higuchi N, Nakamura T, Kitahara T, Honda M, Sasaki H
    • Journal Title

      Biol Pharm Bull

      Volume: 36(11) Pages: 1794-9

    • NAID

      130003382043

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659813
  • [Journal Article] Ocular gene delivery systems using ternary complexes of plasmid DNA, polyethylenimine, and anionic polymers2013

    • Author(s)
      Kurosaki T, Uematsu M, Shimoda K, Suzuma K, Nakai M, Nakamura T, Kitahara T, Kitaoka T, Sasaki H
    • Journal Title

      Biol Pharm Bull

      Volume: 36(1) Pages: 96-101

    • NAID

      130003361352

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659813
  • [Journal Article] Secure splenic delivery of plasmid DNA and its application to DNA vaccine.2013

    • Author(s)
      Kurosaki T, Kodama Y, Muro T, Higuchi N, Nakamura T, Kitahara T, Miyakoda M, Yui K, Sasaki H.
    • Journal Title

      Biological and Pharmaceutical Bulletin

      Volume: 36 Pages: 1800-1806

    • NAID

      130003382044

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590198
  • [Journal Article] Ternary Complex of Plasmid DNA with Protamine and γ-Polyglutamic Acid for Biocompatible Gene Delivery System2013

    • Author(s)
      Kosuke Kanda, Yukinobu Kodama, Tomoaki Kurosaki, Masanobu Imamura, Hiroo Nakagawa, Takahiro Muro, Norihide Higuchi, Tadahiro Nakamura, Takashi Kitahara, Masayuki Honda, Hitoshi Sasaki
    • Journal Title

      Biological and Pharmaceutical Bulletin

      Volume: 36 Pages: 1794-1799

    • NAID

      130003382043

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659813
  • [Journal Article] Secure splenic delivery of plasmid DNA and its application to DNA vaccine2013

    • Author(s)
      Kurosaki T, Kodama Y, Muro T, Higuchi N, Nakamura T, Kitahara T, Miyakoda M, Yui K, Sasaki H
    • Journal Title

      Biol Pharm Bull

      Volume: 36(11) Pages: 1800-6

    • NAID

      130003382044

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659813
  • [Journal Article] Self-assemble gene delivery system for molecular targeting using nucleic acid aptamer2012

    • Author(s)
      Kurosaki T, Higuchi N, Kawakami S, Higuchi Y, Nakamura T, Kitahara T, Hashida M, Sasaki H
    • Journal Title

      Gene

      Volume: 491(2) Pages: 205-9

    • NAID

      120003496558

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659813
  • [Journal Article] Nanoparticles electrostatically coated with folic acid for effective gene therapy2011

    • Author(s)
      Kurosaki T, Morishita T, Kodama Y, Sato K, Nakagawa H, Higuchi N, Nakamura T, Hamamoto T, Sasaki H, Kitahara T
    • Journal Title

      Mol Pharm

      Volume: 8(3) Pages: 913-919

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390010
  • [Journal Article] Immunogenicity of novel nanoparticle-coated MSP-1 C-terminus malaria DNA vaccine using different routes of administration2011

    • Author(s)
      Cherif MS, Shuaibu MN, Kurosaki T, Helegbe GK, Kikuchi M, Yanagi T, Tsuboi T, Sasaki H, Hirayama K.
    • Journal Title

      Vaccine

      Volume: 29(48) Pages: 9038-9050

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390010
  • [Journal Article] Secure and effective gene vector of polyamidoamine dendrimer pharraac eutically modified with anionic polymer2011

    • Author(s)
      Kurosaki T, Yamashita Y, Aki K, Harasawa H, Nakagawa H, Kodama Y, Higuchi N, Nakamura T, Kitahara T, Sasaki H
    • Journal Title

      J Pharm Sci

      Volume: 100 Pages: 4855-4863

    • DOI

      10.1002/jps.22701

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390010
  • [Journal Article] Secure and effective gene vector of polyamidoamine dendrimer pharmaceutically modified with anionic polymer2011

    • Author(s)
      Kurosaki T, Yamashita Y, Aki K, Harasawa H, Nakagawa H, Kodama Y, Higuchi N, Nakamura T, Kitahara T, Sasaki H
    • Journal Title

      J Pharm Sci

      Volume: 100(11) Pages: 4855-4863

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390010
  • [Journal Article] Immunogenicity of novel nanoparticle-coated MSP-1 C-terminus malaria DNA vaccine using different routes of administration2011

    • Author(s)
      Cherif MS, Shuaibu MN, Kurosaki T, Helegbe GK, Kikuchi M, Yanagi T, Tsuboi T, Sasaki H, Hirayama K
    • Journal Title

      Vaccine

      Volume: 29 Pages: 9038-9050

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390010
  • [Journal Article] Secure and effective gene vector of polyamidoamine dendrimer pharmaceutically modified with anionic polymer2011

    • Author(s)
      Kurosaki T, Yamashita Y, Aki K, Harasawa H, Nakagawa H, Kodama Y, Higuchi N, Nakamura T, Kitahara T, Sasaki H
    • Journal Title

      J Pharm Sci

      Volume: 100(11) Pages: 4855-63

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659813
  • [Journal Article] Nanoparticles electrostatically coated with folic acid for effective gene therapy2011

    • Author(s)
      Kurosaki T, Morishita T, Kodama Y, Sato K, Nakagawa H, Higuchi N, Nakamura T, Hamamoto T, Sasaki H, Kitahara T
    • Journal Title

      Mol Pharm

      Volume: 8(3) Pages: 913-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659813
  • [Journal Article] Chondroitin sulfate capsule system for efficient and secure gene delivery2010

    • Author(s)
      Kurosaki T, Kitahara T, Fumoto S, Nishida K, Yamamoto K, Nakagawa H, Kodama Y, Higuchi N, Nakamura T, Sasaki H
    • Journal Title

      J Pharm Pharm Sci

      Volume: 13(3) Pages: 351-361

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390010
  • [Journal Article] Gamma-polyglutamic acid-coated vectors for effective and safe gene therapy2010

    • Author(s)
      Kurosaki T, Kitahara T, Kawakami S, Higuchi Y, Yamaguchi A, Nakagawa H, Kodama Y, Hamamoto T, Hashida M, Sasaki H
    • Journal Title

      J Control Release

      Volume: 142(3) Pages: 404-410

    • NAID

      120002023228

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390010
  • [Journal Article] Gamma-polyglutamic acid-coated vectors for effective and safe gene therapy.2010

    • Author(s)
      Kurosaki T, Kitahara T, Kawakami S, Higuchi Y, Yamaguchi A, Nakagawa H, Kodama Y, Hamamoto T, Hashida M, Sasaki H.
    • Journal Title

      J Control Release.

      Volume: 142 Pages: 404-410

    • NAID

      120002023228

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390010
  • [Journal Article] Chondroitin sulfate capsule system for efficient and secure gene delivery.2010

    • Author(s)
      Kurosaki T, Kitahara T, Fumoto S, Nishida K, Yamamoto K, Nakagawa H, Kodama Y, Higuchi N, Nakamura T, Sasaki H.
    • Journal Title

      J Pharm Pharm Sci

      Volume: 13 Pages: 351-361

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390010
  • [Journal Article] Cationic liposomes-mediated plasmid DNA delivery in murine hepatitis induced by carbon tetrachloride2009

    • Author(s)
      Yoshioka T, Yoshida S, Kurosaki T, Teshima M, Nishida K, Nakamura J, Nakashima M, To H, Kitahara T, Sasaki H
    • Journal Title

      J Liposome Res 23

      Pages: 1-7

    • NAID

      120002223808

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590143
  • [Journal Article] Ternary complexes of pDNA, polyethylenimine, and gamma-polyglutamic acid for gene delivery systems.2009

    • Author(s)
      Kurosaki, T., Kitahara, T., Fumoto, S., Nishida, K., Nakamura, J., Niidome, T., Kodama, Y., Nakagawa, H., To, H., Sasaki, H.
    • Journal Title

      Biomaterials 30

      Pages: 2846-2853

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390010
  • [Journal Article] Cationic liposomes-mediated plasmid DNA delivery in murine hepatitis induced by carbon tetrachloride2009

    • Author(s)
      Yoshioka T, Yoshida S, Kurosaki T, Teshima M, Nishida K, Nakamura J, Nakashima M, To H, Kitahara T, Sasaki H
    • Journal Title

      J Liposome Res

      Volume: 19(2) Pages: 141-147

    • NAID

      120002223808

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390010
  • [Journal Article] Pulmonary gene delivery of hybrid vector, lipopolyplex containing N-lauroylsarcosine, via the systemic route2009

    • Author(s)
      Kurosaki T, Kishikawa R, Matsumoto M, Kodama Y, Hamamoto T, To H, Niidome T, Takayama K, Kitahara T, Sasaki H
    • Journal Title

      J Control Release

      Volume: 136(3) Pages: 213-219

    • NAID

      120001364493

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390010
  • [Journal Article] Cationic liposomes-mediated plasmid DNA delivery in murine hepatitis induced by carbon tetrachloride.2009

    • Author(s)
      Yoshioka, T, Yoshida, S., Kurosaki, T., Teshima, M., Nishida, K., Nakamura, J., Nakashima, M., To, H., Kitahara, T., Sasaki, H.
    • Journal Title

      J.Liposome Res. 23

      Pages: 1-7

    • NAID

      120002223808

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390010
  • [Journal Article] The development of a gene vector electrostatically assembled with a polysaccharide capsule2009

    • Author(s)
      Kurosaki T, Kitahara T, Kawakami S, Nishida K, Nakamura J, Teshima M, Nakagawa H, Kodama Y, To H, Sasaki H
    • Journal Title

      Biomaterials

      Volume: 30(26) Pages: 4427-4434

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390010
  • [Journal Article] Pulmonary gene delivery of hybrid vector, lipopolyplex containing N-lauroylsarcosine, via the systemic route.2009

    • Author(s)
      Kurosaki, T., Kishikawa, R., Matsumoto, M., Kodama, Y., Hamamoto, T., To, H., Niidome, T., Takayama, K., Kitahara, T., Sasaki, H.
    • Journal Title

      J.Control. Release 136

      Pages: 213-219

    • NAID

      120001364493

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390010
  • [Journal Article] Ternary complexes of pDNA, polyethylenimine, and gamma-polyglutamic acid for gene delivery systems2009

    • Author(s)
      Kurosaki T, Kitahara T, Fumoto S, Nishida K, Nakamura J, Niidome T, Kodama Y, Nakagawa H, To H, Sasaki H
    • Journal Title

      Biomaterials

      Volume: 30(14) Pages: 2846-2853

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390010
  • [Journal Article] The development of a gene vector electrostatically assembled with a polysaccharide capsule.2009

    • Author(s)
      Kurosaki, T, Kitahara, T., Kawakami, S., Nishida, K., Nakamura, J., Teshima, M., Nakagawa, H., Kodama, Y., To, H., Sasaki, H.
    • Journal Title

      Biomaterials 30

      Pages: 4427-4434

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390010
  • [Journal Article] Influence of murine hepatitis induced by D-(+)-galactosamine hydrochloride and lipopolysaccharide on gene expression of polyethylenimine/plasmid DNA polyplex2008

    • Author(s)
      Miyanaga K, Yoshioka T, Nakagawa H, Kitahara T, To H, Ichikawa N, Nakashima M, Nishida K, Nakamura J, Sasaki H
    • Journal Title

      Biol Pharm Bull 31

      Pages: 1585-9

    • NAID

      110006839022

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590143
  • [Journal Article] オンチップ心筋拍動細胞ネットワークを用いた抗不整脈薬の薬物応答性の解析2008

    • Author(s)
      中嶋幹郎、大脇裕一、向江俊彦、梅野繁智、柳原克紀、河野茂、冨永留美、荒木良介、寺薗英之、北原隆志、藤秀人、佐々木均
    • Journal Title

      長崎医学会雑誌 83

      Pages: 59-66

    • NAID

      110007148533

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590147
  • [Journal Article] Evaluation of enhanced peritoneum permeability in methylglyoxal-treated rats as a diagnostic method for peritoneal damage2007

    • Author(s)
      S.Fumoto, Y.Nakashima, K.Nishida, H.Sasaki, et. al.
    • Journal Title

      Pharmaceutical Research 24

      Pages: 1891-1896

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590143
  • [Journal Article] Unilateral lung-selective gene transfer following the administration of Naked plasmid DNA onto the pulmonary pleural surface in mice2007

    • Author(s)
      J.Nakamura, S.Fumoto, K.Ariyoshi, H.Sasaki, et. al.
    • Journal Title

      Biol.Pharm.Bull. 30

      Pages: 729-732

    • NAID

      110006271214

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590143
  • [Journal Article] Spleen-selective gene transfer following the administration of naked plasmid DNA onto the spleen surface in mice2007

    • Author(s)
      J.Nakamura, S.Fumoto, R.Kawanami, H.Sasaki, et. al.
    • Journal Title

      Biol.Pharm.Bull. 30

      Pages: 941-945

    • NAID

      110006273294

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590143
  • [Journal Article] Partial hepatectomy enhances polyethylenimine-mediated plasmid DNA delivery2006

    • Author(s)
      Tada Y, Kitahara T, Yoshioka T, Nakamura T, Ichikawa N, Nakashima M, Nishida K, Nakamura J, Sasaki H
    • Journal Title

      Biol Pharm Bull 29

      Pages: 1712-6

    • NAID

      110005664015

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590143
  • [Journal Article] Partial hepatectomy enhances polyethylenimine-mediated plasmid DNA delivery2006

    • Author(s)
      Y.Tada, T.Kitahara, T.Yoshioka, T.Nakamura, H.Sasaki
    • Journal Title

      Biol.Pharm.Bull. 29

      Pages: 1712-1716

    • NAID

      110005664015

    • Data Source
      KAKENHI-PROJECT-18590143
  • [Journal Article] Prolonged blood concentrationof prednisolone after intravenous injection of liposomal palmitoyl prednisolone2006

    • Author(s)
      M.Teshima, S.Fumoto, K.Nishida, J.Nakamura, H.Sasaki
    • Journal Title

      J.Control.Release 112

      Pages: 320-328

    • Data Source
      KAKENHI-PROJECT-18590143
  • [Journal Article] Stomach-selective gene transfer following the administration of naked plasmid DNA onto the gastric serosal surface in mice2006

    • Author(s)
      J.Nakamura, S.Fumoto, K.Shoji, Y.Kodama, H.Sasaki
    • Journal Title

      Biol.Pharm.Bull. 29

      Pages: 2082-2086

    • NAID

      110004810296

    • Data Source
      KAKENHI-PROJECT-18590143
  • [Journal Article] In vitro activity of lauric acid or myristylamine in combination with six antimicrobial agents against MRSA2006

    • Author(s)
      T.Kitahara, Y.Aoyama, Y.Hirakata, S.Kanmihira, H.Sasaki
    • Journal Title

      Int.J.Antimicrob.Agents 27

      Pages: 51-57

    • Data Source
      KAKENHI-PROJECT-18590143
  • [Journal Article] Influence of disease stage on polyethylenimine-mediated plasmid DNA delivery in murine hepatitis2006

    • Author(s)
      Sasaki H, Yoshida S, Kitahara T, Yoshioka T, Nakagawa H, Nakamura T, Ichikawa N, Nishida K, Nakamura J, Nakashima M
    • Journal Title

      Int J Pharm 318

      Pages: 139-45

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590143
  • [Journal Article] PEGylated liposomes loading palmitoyl prednisolone for prolonged blood concentration of prednisolone2006

    • Author(s)
      M.Teshima, S.Kawakami, S.Fumoto, K.Nishida, H.Sasaki
    • Journal Title

      Biol.Pharm.Bull. 29

      Pages: 1436-1440

    • NAID

      110005602317

    • Data Source
      KAKENHI-PROJECT-18590143
  • [Journal Article] Influence of disease stage on polyethyleniine-mediated plasmid DNA delivery in murine fepatitis2006

    • Author(s)
      H.Sasaki, S.Yoshida, T.Kitahara, T.Yoshioka, H.Nakagawa
    • Journal Title

      Inter.J.Pharmaceu 318

      Pages: 139-145

    • Data Source
      KAKENHI-PROJECT-18590143
  • [Journal Article] Unilateral kindney-selective gene transfer following the administration of naked plasmid DNA to the kidney surface in mice2005

    • Author(s)
      Ryu Hirayama, Hitoshi Sasaki, Junzo Nakamura et al.
    • Journal Title

      Biological & Pharmaceutical Bulletin 28・1

      Pages: 181-184

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590133
  • [Journal Article] Unilateral kidney-selective gene transfer following the administration of naked plasmid DNA to the kidney surface in mice2005

    • Author(s)
      Mikiro Nakashima, Hitoshi Sasaki, Junzo Nakamura et al.
    • Journal Title

      Biological & Pharmaceutical Bulletin 28

      Pages: 181-184

    • NAID

      110003665796

    • Data Source
      KAKENHI-PROJECT-15590133
  • [Journal Article] Self-association properties of 4-[1-hydroxy-1-methylethyl]-2-propyl-1-[4-[2 [tetrazole-5-yl]phenyl]phenyl]methylimidazole-5-carboxylic acid monohydrate (CS-088), an antiglaucoma opthalmic agent2005

    • Author(s)
      T.Kikuchi, K.Ito, M.Suzuki, A.Kusai, K.Iseki, H.Sasaki
    • Journal Title

      Int. J. Pharmaceu. 290

      Pages: 100-106

    • Data Source
      KAKENHI-PROJECT-15590133
  • [Journal Article] Unilateral kidney-selective gene transfer following the administration of naked plasmid DNA to the kidney surface in mice.2005

    • Author(s)
      R.Hirayama, K.Nishida, S.Fumoto, M, Nakashima, H.Sasaki, J.Nakamura
    • Journal Title

      Biol. Pharm. Bull. 28

      Pages: 181-184

    • NAID

      110003665796

    • Data Source
      KAKENHI-PROJECT-15590133
  • [Journal Article] Effect of solution composition of plasmid DNA on gene transfection following liver surface administration in mice.2005

    • Author(s)
      R.Hirayama, S.Fumoto, K.Nishida, M.Nakashima, H.Sasaki, J.Nakamura
    • Journal Title

      Biol. Pharm. Bull. 28

      Pages: 2166-2169

    • NAID

      110003666420

    • Data Source
      KAKENHI-PROJECT-15590133
  • [Journal Article] Unilateral kidney-selective gene transfer following the administration of naked plasmid DNA to the kidney surface in mice2005

    • Author(s)
      Ryu Hirayama, Hitoshi Sasaki, Junzo Nakamura et al.
    • Journal Title

      Biological & Pharmaceutical Bulletin, 28-1

      Pages: 181-184

    • NAID

      110003665796

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590133
  • [Journal Article] Synergistic effect of EDTA and boric acid on corneal penetration of CS-088.2005

    • Author(s)
      T.Kikuchi, M.Suzuki, A.Kusai, K.Iseki, H.Sasaki
    • Journal Title

      Int. J. Pharmaceu. 290

      Pages: 83-89

    • Data Source
      KAKENHI-PROJECT-15590133
  • [Journal Article] Delivery advantage to the unilateral kedney by direct drug application to the kidney surface in rats and pharmacokinetic verification based on a physiological model.2005

    • Author(s)
      K.Nishida, M, Kamenosono, A, Kuma, S.Fumoto, T.Mukai, M.Nakashima, H.Sasaki, J.Nakamura
    • Journal Title

      Journal of Drug Targeting 13

      Pages: 215-223

    • Data Source
      KAKENHI-PROJECT-15590133
  • [Journal Article] Effect of solution composition of plasmid DNA on gene transfection following liver surface administration in mice2005

    • Author(s)
      Ryu Hirayama, Hitoshi Sasaki, Junzo Nakamura et al.
    • Journal Title

      Biological & Pharmaceutical Bulletin, 28-11

      Pages: 2166-2169

    • NAID

      110003666420

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590133
  • [Journal Article] Mechanism of permeability-enhancing effect of EDTA and bolic acid on the corneal penetration of 4-[1-hydroxy-1-methylethyl]-2-propyl-1-[4-[2-[tetrazole-5-yl]phenyl]phenyl]methylimidazole-5-carboxylic acid monohydrate (CS-088).2005

    • Author(s)
      T.Kikuchi, M.Suzuki, A.Kusai, K.Iseki, H.Sasaki, K.Nakashima
    • Journal Title

      Int. J. Pharmaceu. 290

      Pages: 107-114

    • Data Source
      KAKENHI-PROJECT-15590133
  • [Journal Article] Effect of solution composition of plasmid DNA on gene transfection following liver surface administration in mice2005

    • Author(s)
      Ryu Hirayama, Hitoshi Sasaki, Junzo Nakamura et al.
    • Journal Title

      Biological & Pharmaceutical Bulletin 28・11

      Pages: 2166-2169

    • NAID

      110003666420

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590133
  • [Journal Article] Pharmacokinetics of phenol red in rat models of liver damage prepared by liver targeting of carbon tetrachloride2004

    • Author(s)
      Takahiro Mukai, Hitoshi Sasaki, Junzo Nakamura et al.
    • Journal Title

      Biological & Pharmaceutical Bulletin 27

      Pages: 595-597

    • NAID

      110003608814

    • Data Source
      KAKENHI-PROJECT-15590133
  • [Journal Article] In vivo gene transfection via intravitreal injection of cationic liposome/plasmid DNA complexes in rabbits2004

    • Author(s)
      Shigeru Kawakami, Junzo Nakamura, Hitoshi Sasaki et al.
    • Journal Title

      International Journal of Pharmaceutics 278・2

      Pages: 255-262

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590133
  • [Journal Article] In vivo gene transfection via intravitreal injection of cationic liposome/plasmid DNA complexes in rabbits2004

    • Author(s)
      Shigeru Kawakami, Junzo Nakamura, Hitoshi Sasaki et al.
    • Journal Title

      International Journal of Pharmaceutics 278

      Pages: 253-262

    • Data Source
      KAKENHI-PROJECT-15590133
  • [Journal Article] Ocular pharmacokinetic/pharmacodynamic (PK/PD) modeling for bunazosin after instillation into rabbits2004

    • Author(s)
      Koji Sasanaka, Junzo Nakamura, Hitoshi Sasaki et al.
    • Journal Title

      Pharmaceutical Roserch 21

      Pages: 770-776

    • Data Source
      KAKENHI-PROJECT-15590133
  • [Journal Article] Liver site-specific gene transfer following the administration of naked plasmid DNA to the liver surface in mice2004

    • Author(s)
      Koyo Nishida, Hitoshi Sasaki, Junzo Nakamura et al.
    • Journal Title

      Biological & Pharmaceutical Bulletin 27

      Pages: 1697-1699

    • NAID

      110003608683

    • Data Source
      KAKENHI-PROJECT-15590133
  • [Journal Article] Ocular pharmacokinetic/pharmacodynamic (PK/PD) modeling for bunazosin after instillation into rabbits2004

    • Author(s)
      Koji Sakanaka, Junzo Nakamura, Hitoshi Sasaki et al.
    • Journal Title

      Pharmaceutical Research 21・5

      Pages: 771-776

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590133
  • [Journal Article] Prednisolone retention in integrated liposomes by chemical approach and pharmaceutical approach2004

    • Author(s)
      Mugen Teshima, Koyo Nishida, Hitoshi Sasaki et al.
    • Journal Title

      Journal of Controlled Release 97・2

      Pages: 211-218

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590133
  • [Journal Article] Prednisolone retention in integrated liposomes by chemical approach and pharmaceutical approach2004

    • Author(s)
      Mugen Teshima, Koyo Nishida, Hitoshi Sasaki et al.
    • Journal Title

      Journal of Controlled Release, 97-2

      Pages: 211-218

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590133
  • [Journal Article] In vivo gene transfection via intravitreal injection of cationic liposome/plasmid DNA complexes in rabbits2004

    • Author(s)
      Shigeru Kawakami, Junzo Nakamura, Hitoshi Sasaki et al.
    • Journal Title

      International Journal of Pharmaceutics, 278-2

      Pages: 255-262

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590133
  • [Journal Article] Ocular pharmacokinetic/pharmacodynamic modeling for bunazosin after instillation into rabbits2004

    • Author(s)
      Koji Sakanaka, Junzo Nakamura, Hitoshi Sasaki et al.
    • Journal Title

      Pharmaceutical Research, 21-5

      Pages: 770-776

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590133
  • [Journal Article] Prednisolone retention in integrated liposomes by chemical approach and pharmaceutical approach2004

    • Author(s)
      Mugen Teshima, Mikiro Nakashima, Hitoshi Sasaki et al.
    • Journal Title

      Journal of Controlled Release 97

      Pages: 211-218

    • Data Source
      KAKENHI-PROJECT-15590133
  • [Journal Article] One-side-coated insert as a unique ophthalmic drug delivery system2003

    • Author(s)
      Hitoshi Sasaki, Koyo Nishida, Mikiro Nakashima et al.
    • Journal Title

      Journal of Controlled Release, 92-3

      Pages: 241-247

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590133
  • [Journal Article] One-side-coated insert as a unique ophthalmic drug delivery system2003

    • Author(s)
      Hitoshi Sasaki, Koyo Nishida, Mikiro Nakashima et al.
    • Journal Title

      Journal of Controlled Release 92・3

      Pages: 241-247

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590133
  • [Patent] 薬物送達複合体2010

    • Inventor(s)
      佐々木均, 黒崎友亮, 北原隆志, 藤秀人, 由井克之, 平山謙二, 森田公一
    • Industrial Property Rights Holder
      長崎大学
    • Industrial Property Number
      2010-043186
    • Filing Date
      2010-02-26
    • Data Source
      KAKENHI-PROJECT-21390010
  • [Patent] 新規ナノボールの創製2010

    • Inventor(s)
      佐々木均、黒崎友亮、北原隆志、他
    • Industrial Property Rights Holder
      国立大学法人長崎大学
    • Industrial Property Number
      2010-043186
    • Filing Date
      2010-02-26
    • Data Source
      KAKENHI-PROJECT-21390010
  • [Presentation] 生体分解型siRNAベクターの構築と有用性評価2018

    • Author(s)
      柿木 優希, 兒玉 幸修, 北原 隆志, 佐々木 均
    • Organizer
      第34回日本DDS学会学術集会
    • Data Source
      KAKENHI-PROJECT-18H02589
  • [Presentation] 大腸がん腹膜播種に対するVEGF-siRNAナノ粒子の開発2018

    • Author(s)
      大倉 真生, 兒玉 幸修, 北原 隆志, 佐々木 均
    • Organizer
      第34回日本DDS学会学術集会
    • Data Source
      KAKENHI-PROJECT-18H02589
  • [Presentation] 大腸がん腹膜播種に対するMDM2-siRNA複合体の有効性評価2018

    • Author(s)
      丸田 由佳理, 兒玉 幸修, 北原 隆志, 佐々木 均
    • Organizer
      日本薬剤学会第33年会
    • Data Source
      KAKENHI-PROJECT-18H02589
  • [Presentation] c-Myc-siRNA三重複合体によるメラノーマ増殖抑制に関する基礎的検討2018

    • Author(s)
      三枝 由香莉, 兒玉 幸修, 北原 隆志, 佐々木 均
    • Organizer
      日本薬剤学会第33年会
    • Data Source
      KAKENHI-PROJECT-18H02589
  • [Presentation] VEGF-siRNA複合体によるメラノーマ肺転移の抑制2018

    • Author(s)
      岡田 明莉, 兒玉 幸修, 北原 隆志, 佐々木 均
    • Organizer
      第34回日本DDS学会学術集会
    • Data Source
      KAKENHI-PROJECT-18H02589
  • [Presentation] ポリアミノ酸で構築した生体分解型マラリアナノワクチンの開発2016

    • Author(s)
      根岸 智奈美、兒玉 幸修、北原 隆志、佐々木 均
    • Organizer
      日本薬剤学会第31年会
    • Place of Presentation
      長良川国際会議場(岐阜県・岐阜市)
    • Year and Date
      2016-05-21
    • Data Source
      KAKENHI-PROJECT-26293034
  • [Presentation] グリコサミノグリカンで被膜した生体分解型遺伝子ベクターの開発2016

    • Author(s)
      三枝 由香莉、兒玉 幸修、岩永 真理恵、北原 隆志、佐々木 均
    • Organizer
      日本薬剤学会第31年会
    • Place of Presentation
      長良川国際会議場(岐阜県・岐阜市)
    • Year and Date
      2016-05-21
    • Data Source
      KAKENHI-PROJECT-26293034
  • [Presentation] 関節リウマチ治療を目的としたメトトレキサートを構成成分とする遺伝子ベクターの開発2016

    • Author(s)
      小林 瑞希、兒玉 幸修、北原 隆志、佐々木 均
    • Organizer
      日本薬剤学会第31年会
    • Place of Presentation
      長良川国際会議場(岐阜県・岐阜市)
    • Year and Date
      2016-05-21
    • Data Source
      KAKENHI-PROJECT-26293034
  • [Presentation] 抗原提示細胞標的化ナノ粒子を用いた新規がんワクチンの開発2015

    • Author(s)
      花村啓紀、兒玉幸修、北原隆志、中嶋幹郎、佐々木 均
    • Organizer
      日本薬剤学会第30年会
    • Place of Presentation
      長崎ブリックホール(長崎県長崎市)
    • Year and Date
      2015-05-21
    • Data Source
      KAKENHI-PROJECT-26293034
  • [Presentation] アニオン性三重複合体の眼疾患用遺伝子ベクターとしての有用性評価2015

    • Author(s)
      永原忠幸、兒玉幸修、北原隆志、中嶋幹郎、佐々木 均
    • Organizer
      日本薬剤学会第30年会
    • Place of Presentation
      長崎ブリックホール(長崎県長崎市)
    • Year and Date
      2015-05-21
    • Data Source
      KAKENHI-PROJECT-26293034
  • [Presentation] pH緩衝能の増大と毒性軽減を目的とした四重複合体の開発と有用性評価2015

    • Author(s)
      上田由貴、兒玉幸修、三枝由香莉、北原隆志、佐々木 均
    • Organizer
      日本薬剤学会第30年会
    • Place of Presentation
      長崎ブリックホール(長崎県長崎市)
    • Year and Date
      2015-05-21
    • Data Source
      KAKENHI-PROJECT-26293034
  • [Presentation] アニオン性デンドリプレックスを用いた遺伝子デリバリーシステムの開発2015

    • Author(s)
      野田 稜、兒玉幸修、黑﨑友亮、中村忠博、北原隆志、佐々木 均
    • Organizer
      日本薬剤学会第30年会
    • Place of Presentation
      長崎ブリックホール(長崎県長崎市)
    • Year and Date
      2015-05-21
    • Data Source
      KAKENHI-PROJECT-26293034
  • [Presentation] 生体分解型DNAナノワクチンによる悪性黒色腫の増殖抑制2015

    • Author(s)
      徳永彩子、兒玉幸修、北原隆志、佐々木 均
    • Organizer
      第31回日本DDS学会学術集会
    • Place of Presentation
      京王プラザホテル(東京都新宿区)
    • Year and Date
      2015-07-02
    • Data Source
      KAKENHI-PROJECT-26293034
  • [Presentation] Dendrigraft poly-L-lysine を基材とした遺伝子ベクターの有用性評価2015

    • Author(s)
      徳永彩子、兒玉幸修、樋口則英、北原隆志、佐々木 均
    • Organizer
      日本薬剤学会第30年会
    • Place of Presentation
      長崎ブリックホール(長崎県長崎市)
    • Year and Date
      2015-05-21
    • Data Source
      KAKENHI-PROJECT-26293034
  • [Presentation] センチネルリンパ節イメージングを目指した蛍光標識γ-ポリグルタミン酸複合体の開発2014

    • Author(s)
      萩森政頼, 畑辺恵里, 佐野紘平, 佐々木均, 佐治英郎, 向高弘
    • Organizer
      第9回日本分子イメージング学会学術集会
    • Place of Presentation
      千里ライフサイエンスセンター
    • Data Source
      KAKENHI-PROJECT-24390294
  • [Presentation] センチネルリンパ節の蛍光イメージングを目指したγ-ポリグルタミン酸被覆ナノ粒子の作製2014

    • Author(s)
      千石梓, 畑辺恵里, 萩森政頼, 佐野紘平, 佐々木均, 佐治英郎, 向高弘
    • Organizer
      第14回放射性医薬品・画像診断薬研究会
    • Place of Presentation
      京都勧業館, 京都
    • Year and Date
      2014-09-13
    • Data Source
      KAKENHI-PROJECT-24390294
  • [Presentation] Dendrigraft poly-L-lysine を用いた生体内分解型遺伝子ベクターの開発2013

    • Author(s)
      塩川 裕美、兒玉 幸修、北原 隆志、佐々木 均
    • Organizer
      日本薬剤学会第28年会
    • Place of Presentation
      名古屋
    • Year and Date
      2013-05-25
    • Data Source
      KAKENHI-PROJECT-23659813
  • [Presentation] 樹状細胞標的型ナノデバイスを用いたマラリアDNA ナノワクチンの開発2013

    • Author(s)
      西垣 和香、兒玉 幸修、北原 隆志、佐々木 均
    • Organizer
      第30回日本薬学会九州支部大会
    • Place of Presentation
      佐世保
    • Year and Date
      2013-12-08
    • Data Source
      KAKENHI-PROJECT-23659813
  • [Presentation] 生体イメージングを目指したγ-ポリグルタミン酸被覆蛍光ナノ粒子の作製2013

    • Author(s)
      畑辺恵里, 萩森政頼, 佐野紘平, 佐々木均, 向高弘
    • Organizer
      第63回日本薬学会近畿支部大会
    • Place of Presentation
      同志社女子大学(京田辺キャンパス)
    • Data Source
      KAKENHI-PROJECT-24390294
  • [Presentation] ポリヌクレオチド被膜型複合体による脾臓指向性新規遺伝子ベクターの開発2013

    • Author(s)
      矢次 結衣子、兒玉 幸修、大久保 智佳子、北原 隆志、佐々木 均
    • Organizer
      日本薬剤学会第28年会
    • Place of Presentation
      名古屋
    • Year and Date
      2013-05-25
    • Data Source
      KAKENHI-PROJECT-23659813
  • [Presentation] Fetuin 被膜型複合体による新規遺伝子ベクターの構築2013

    • Author(s)
      兒玉 幸修、北原 隆志、江頭 かの子、中嶋 幹郎、樋口 則英、中村 忠博、佐々木 均
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      横浜
    • Year and Date
      2013-03-28
    • Data Source
      KAKENHI-PROJECT-23659813
  • [Presentation] 肝細胞選択的なグリチルリチン含有遺伝子ベクターの開発2012

    • Author(s)
      原内 智慧、川鍋 早紀、黒崎 友亮、兒玉 幸修、北原 隆志、佐々木 均
    • Organizer
      日本薬剤学会第27年会
    • Place of Presentation
      神戸
    • Year and Date
      2012-05-24
    • Data Source
      KAKENHI-PROJECT-23659813
  • [Presentation] 制癌剤と遺伝子同時送達を目的としたメトトレキサート被膜型遺伝子ベクターの開発2012

    • Author(s)
      兒玉 幸修、黒崎 友亮、江頭 かの子、中嶋 幹郎、中川 博雄、樋口 則英、中村 忠博、北原 隆志、佐々木 均
    • Organizer
      日本薬学会第132年会
    • Place of Presentation
      札幌
    • Year and Date
      2012-03-31
    • Data Source
      KAKENHI-PROJECT-23659813
  • [Presentation] Sentinel lymph node imaging with a novel radiolabeled γ-polyglutamic acid complex2012

    • Author(s)
      Sano K., Iwamiya Y., Kurosaki T., Ogawa M., Magata Y., Sasaki H., Oshima T., Maeda M., Mukai T ,
    • Organizer
      The Society of Nuclear Medicine 59th Annual Meeting
    • Place of Presentation
      Miami Beach (USA)
    • Year and Date
      2012-06-10
    • Data Source
      KAKENHI-PROJECT-24390294
  • [Presentation] 安全かつ効果的な眼疾患用新規遺伝子ベクターの開発2012

    • Author(s)
      佐々木均、兒玉幸修、黑﨑友亮、樋口則英、北原隆志、中村忠博
    • Organizer
      第32回日本眼薬理学会学術集会
    • Place of Presentation
      ピアザ淡海(滋賀県大津市)
    • Data Source
      KAKENHI-PROJECT-23659813
  • [Presentation] ホスファチジルセリンアナログを用いた脾臓指向性遺伝子導入ベクターの開発2012

    • Author(s)
      大久保 智佳子、仲宗根 ちひろ、黒崎 友亮、兒玉 幸修、北原 隆志、佐々木 均
    • Organizer
      日本薬剤学会第27年会
    • Place of Presentation
      神戸
    • Year and Date
      2012-05-24
    • Data Source
      KAKENHI-PROJECT-23659813
  • [Presentation] 静電的自己組織化を基盤としたアニオン性siRNA ベクターの開発2012

    • Author(s)
      塩川 裕美、兒玉 幸修、原内 智慧、北原 隆志、佐々木 均
    • Organizer
      第29回日本薬学会九州支部大会
    • Place of Presentation
      熊本
    • Year and Date
      2012-12-08
    • Data Source
      KAKENHI-PROJECT-23659813
  • [Presentation] 安全かつ効果的な眼疾患用新規遺伝子ベクターの開発2012

    • Author(s)
      佐々木 均、兒玉 幸修、黑﨑 友亮、樋口 則英、北原 隆志、中村 忠博
    • Organizer
      第32回日本眼薬理学会
    • Place of Presentation
      滋賀
    • Year and Date
      2012-09-15
    • Data Source
      KAKENHI-PROJECT-23659813
  • [Presentation] 三重構造を有した生体分解型遺伝子ベクターの構築2011

    • Author(s)
      黒崎友亮、川上茂、橋田充、佐々木均
    • Organizer
      第27回日本DDS学会
    • Place of Presentation
      東京
    • Year and Date
      2011-06-09
    • Data Source
      KAKENHI-PROJECT-21390010
  • [Presentation] グリチルリチン被膜型肝指向性遺伝子ベクターの開発2011

    • Author(s)
      川鍋早紀、黒崎友亮、兒玉幸修、北原隆志、佐々木均
    • Organizer
      第28回日本薬学会九州支部大会
    • Place of Presentation
      福岡
    • Year and Date
      2011-12-10
    • Data Source
      KAKENHI-PROJECT-21390010
  • [Presentation] 三重複合体による新規遺伝子ベクターの開発:コンドロイチン硫酸被膜型デンドリプレックス2011

    • Author(s)
      今村政信、黒崎友亮、兒玉幸修、北原隆志、佐々木均
    • Organizer
      第27回日本DDS学会
    • Place of Presentation
      東京
    • Year and Date
      2011-06-09
    • Data Source
      KAKENHI-PROJECT-21390010
  • [Presentation] Polyplex of pDNA with poly-L-lysine, poly-L-histidine, and γ-polyglutamic acid for biocompatible gene delivery system2011

    • Author(s)
      Yukinobu Kodama, Tomoaki Kurosaki, Kanoko Egashira, Tadahiro Nakamura, Takashi Kitahara, Hitoshi Sasaki
    • Organizer
      日本薬物動態学会第26回年会
    • Place of Presentation
      広島
    • Year and Date
      2011-11-17
    • Data Source
      KAKENHI-PROJECT-23659813
  • [Presentation] 静電的相互作用を利用した葉酸修飾型遺伝子ベクターの開発2011

    • Author(s)
      黒崎友亮、川上茂、橋田充、佐々木均
    • Organizer
      日本薬剤学会第26年会
    • Place of Presentation
      東京
    • Year and Date
      2011-05-29
    • Data Source
      KAKENHI-PROJECT-21390010
  • [Presentation] 注射薬の後発医薬品に関する品質及び安全性の評価2010

    • Author(s)
      中嶋幹郎、荒木良介、中嶋弥穂子、中村純三、佐々木均、八坂貴宏
    • Organizer
      第4回日本ジェネリック医薬品学会学術大会
    • Place of Presentation
      さいたま
    • Data Source
      KAKENHI-PROJECT-20590147
  • [Presentation] 自己組織化により形成される葉酸修飾型遺伝子ベクターの開発2010

    • Author(s)
      森下圭美、黒崎友亮、北原隆志、中村忠博、籐秀人、佐々木均
    • Organizer
      第27回日本薬学会九州支部大会
    • Place of Presentation
      長崎
    • Year and Date
      2010-12-11
    • Data Source
      KAKENHI-PROJECT-21390010
  • [Presentation] 脾臓標的化遺伝子ベクターの開発とDNAワクチンベクターへの応用2010

    • Author(s)
      黒崎友亮、北原隆志、兒玉幸修、西田孝洋、麓伸太郎、佐々木均
    • Organizer
      日本薬剤学会第25年会
    • Place of Presentation
      徳島
    • Year and Date
      2010-05-13
    • Data Source
      KAKENHI-PROJECT-21390010
  • [Presentation] Ternary complexes of pDNA with cationic polymer and anionic polymer for secure gene delivery systems2010

    • Author(s)
      T.Kurosaki, T.Kitahara, T.Nakamura, H.Sasaki
    • Organizer
      FIP Pharmaceutical Sciences 2010 world congress
    • Place of Presentation
      New Orleans
    • Year and Date
      2010-11-18
    • Data Source
      KAKENHI-PROJECT-21390010
  • [Presentation] Dendrimerを用いた三次元型遺伝子ベクターの開発2010

    • Author(s)
      山下祐未、黒崎友亮、森下圭美、兒玉幸修、北原隆志、佐々木均
    • Organizer
      第27回日本薬学会九州支部大会
    • Place of Presentation
      長崎
    • Year and Date
      2010-12-11
    • Data Source
      KAKENHI-PROJECT-21390010
  • [Presentation] Dendrimerを用いた三元型遺伝子ベクターの開発2010

    • Author(s)
      山下祐未、黒崎友亮、森下圭美、兒玉幸修、北原隆志、佐々木均
    • Organizer
      第27回日本薬学会九州支部大会
    • Place of Presentation
      長崎
    • Year and Date
      2010-12-11
    • Data Source
      KAKENHI-PROJECT-21390010
  • [Presentation] γ-Polyglutamic acid被膜型遺伝子ベクターの開発2010

    • Author(s)
      黒崎友亮、北原隆志、兒玉幸修、藤秀人、濱本知之、佐々木均
    • Organizer
      第26回日本DDS学会
    • Place of Presentation
      大阪
    • Year and Date
      2010-06-17
    • Data Source
      KAKENHI-PROJECT-21390010
  • [Presentation] Pulmonary gene delivery of hybrid vector, lipopolyplex containing N-lauroylsarcosine, via systemic route.2010

    • Author(s)
      H.Sasaki, T.Kurosaki, H.To, T.Kitahara
    • Organizer
      FIP Pharmaceutical Sciences 2010 world congress
    • Place of Presentation
      New Orleans
    • Year and Date
      2010-11-18
    • Data Source
      KAKENHI-PROJECT-21390010
  • [Presentation] 負電荷高分子を用いた被膜型遺伝子導入ベクターの開発2009

    • Author(s)
      黒崎友亮、北原隆志、麓伸太郎、西田孝洋、中村純三、藤秀人、佐々木均
    • Organizer
      日本薬剤学会第24年会
    • Place of Presentation
      静岡
    • Year and Date
      2009-05-21
    • Data Source
      KAKENHI-PROJECT-21390010
  • [Presentation] PULMONARY GENE DELIVERY OF HYBRID VECTOR, LIPOPOLYPLEX CONTAINING N-LAUROYLSARCOSINE, VIASYSTEMIC ROUTE.2009

    • Author(s)
      Tomoaki Kurosaki, Kozo Takayama, Takashi Kitahara, Tomoyuki Hamamoto, Hitoshi Sasaki
    • Organizer
      Asian Federation for Pharmaceutical Sciences 2009
    • Place of Presentation
      福岡
    • Year and Date
      2009-10-16
    • Data Source
      KAKENHI-PROJECT-21390010
  • [Presentation] 新規遺伝子ベクターの開発 : カルシウムイオンを介したプラスミドDNA-アニオン性リポソーム複合体2009

    • Author(s)
      中井將人、黒崎友亮、児玉幸修、藤秀人、浜本知之、北原隆志、佐々木均
    • Organizer
      第26回 日本薬学会九州支部大会
    • Place of Presentation
      福岡
    • Year and Date
      2009-12-12
    • Data Source
      KAKENHI-PROJECT-21390010
  • [Presentation] COMPLEX OF PLASMID DNA WITH N-LAUROYLSARCOSINE LIPOSOMES THROUGH CALCIUM BRIDGIHG FOR EFFECTIVE AND SECURE GENE DELIVERY2009

    • Author(s)
      Masato Nakai, Tomoaki Kurosaki, Yukinobu Kodama, Takashi Kitahara, Hitoshi Sasaki
    • Organizer
      Asian Federation for Pharmaceutical Sciences 2009
    • Place of Presentation
      福岡
    • Year and Date
      2009-10-17
    • Data Source
      KAKENHI-PROJECT-21390010
  • [Presentation] 新規遺伝子ベクターの開発 : カルシウムイオンを介したプラスミドDNA-アニオン性リポソーム複合体2009

    • Author(s)
      中井將人、黒崎友亮、児玉幸修、藤秀人、浜本知之、北原隆志、佐々木均
    • Organizer
      第24回 長崎DDS研究会
    • Place of Presentation
      長崎
    • Year and Date
      2009-12-18
    • Data Source
      KAKENHI-PROJECT-21390010
  • [Presentation] 静電的相互作用を基盤とした多糖被膜型遺伝子ベクターの開発と解析2009

    • Author(s)
      黒崎友亮、濱本知之、北原隆志、藤秀人、佐々木均
    • Organizer
      遺伝子デリバリー研究会 第9回シンポジウム
    • Place of Presentation
      大阪
    • Year and Date
      2009-07-09
    • Data Source
      KAKENHI-PROJECT-21390010
  • [Presentation] γ-Polyglutamic acid被膜型遺伝子ベクターの開発とメカニズムの解明2009

    • Author(s)
      佐々木均、黒崎友亮、濱本知之、麓伸太郎、西田孝洋、北原隆志
    • Organizer
      日本薬剤学会第24年会
    • Place of Presentation
      静岡
    • Year and Date
      2009-05-23
    • Data Source
      KAKENHI-PROJECT-21390010
  • [Presentation] 肺指向性を持つ全身投与型遺伝子ベクターの開発と解析2009

    • Author(s)
      黒崎友亮、高山幸三、北原隆志、麓伸太郎、西田孝洋、濱本知之、佐々木均
    • Organizer
      第25回日本DDS学会
    • Place of Presentation
      東京
    • Year and Date
      2009-07-03
    • Data Source
      KAKENHI-PROJECT-21390010
  • [Presentation] INFLUENCE OF DISEASE STAGE ON POLYPLEX AND LIPOPLEX MEDIATED GENE DELIVERY IN MURINE HEPATITIS2009

    • Author(s)
      Hitoshi Sasaki, Tomoaki Kurosaki, Hideto To, Tomoyuki Hamamoto, Takashi Kitahara
    • Organizer
      Asian Federation for Pharmaceutical Sciences 2009
    • Place of Presentation
      福岡
    • Year and Date
      2009-10-17
    • Data Source
      KAKENHI-PROJECT-21390010
  • [Presentation] Influence of murine hepatitis induced by D-(+)-galactos amine hydrochloride and lipopolysaccharide on gene explession of polyethyleneimine/pDNA polyplex2008

    • Author(s)
      Sasaki, H, et al.
    • Organizer
      2008 AAPS Annual Meeting and Exposition.
    • Place of Presentation
      Atlanta, USA
    • Year and Date
      2008-11-19
    • Data Source
      KAKENHI-PROJECT-18590143
  • [Presentation] Effect of disease stage on gene expression by polyplex and lipoplex in murine hepatitis induced by carbon tetrachloride2008

    • Author(s)
      Teshima, M., Yoshida, S., Fumoto, S., Nishida, K., Nakamura, J., Nakashima, M., Hamamoto, T., To, H., Kitahara, T., Sasaki, H.
    • Organizer
      23rd JSSX Annual Meeting
    • Place of Presentation
      Kumamoto, Japan
    • Data Source
      KAKENHI-PROJECT-18590143
  • [Presentation] Influence of murine hepatitis induced by D-(+)-galactosamine hydrochloride and lipopolysaccharide on gene explession of polyethyleneimine/pDNA polyplex2008

    • Author(s)
      Sasaki, H., Kurosaki, T., To, H., Kitahara, T.
    • Organizer
      2008 AAPS Annual Meeting and Exposition
    • Place of Presentation
      Atlanta, USA
    • Data Source
      KAKENHI-PROJECT-18590143
  • [Presentation] Topics of Individualised Medicine2007

    • Author(s)
      H.Sasaki
    • Organizer
      World Congress of Pharmacy and Pharmaceutical Sciences 2007
    • Place of Presentation
      Beijing,China
    • Year and Date
      2007-09-06
    • Data Source
      KAKENHI-PROJECT-18590143
  • [Presentation] 肝再生の遺伝子デリバリーに対する影響-肝切除マウスにおけるpolyethylenimine/pDNA複合体の遺伝子発現2006

    • Author(s)
      山内浩子, 夛田勇巳, 一川暢宏, 籐秀人, 佐々木均, 中嶋幹郎, 西田孝洋, 中村純三
    • Organizer
      日本薬学会第126年会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-18590143
  • [Presentation] Ichikawa N : Delivery timing of plasmid DNA with non-viral carrier in murine hepatitis2006

    • Author(s)
      Sasaki H, Yoshida S, Kitahara T, To H
    • Organizer
      21st FAPA congress
    • Place of Presentation
      Yokohama, Japan
    • Data Source
      KAKENHI-PROJECT-18590143
  • [Presentation] Partial hepatectomy enhances polyethylenimine-mediated plasmid DNA delivery2006

    • Author(s)
      Sasaki H
    • Organizer
      The 66th World Congress of Pharmacy and Pharmaceutical Sciences(FIP 2006)
    • Place of Presentation
      Salvador Bahia, Brazil
    • Data Source
      KAKENHI-PROJECT-18590143
  • [Presentation] Polyethylenimineを用いた遺伝子デリバリーへの病態の影響-四塩化炭素誘発肝障害マウスにおける検討2006

    • Author(s)
      佐々木均, 山内浩子, 夛田勇巳, 一川暢宏, 籐秀人, 中嶋幹郎, 西田孝洋, 中村純三
    • Organizer
      日本薬学会第126年会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-18590143
  • [Presentation] Nanoparticles electrostatically coated with folic acid for effective and safe gene delivery

    • Author(s)
      Hitoshi Sasaki, Yukinobu Kodama, Tamami Morishita, Takashi Kitahara
    • Organizer
      5th Pharmaceutical Sciences World Congress
    • Place of Presentation
      メルボルン(オーストラリア)
    • Year and Date
      2014-04-13 – 2014-04-16
    • Data Source
      KAKENHI-PROJECT-26293034
  • [Presentation] Nanoparticles electrostatically coated with folic acid for effective and safe gene delivery

    • Author(s)
      Hitoshi Sasaki, Yukinobu Kodama, Tamami Morishita, Takashi Kitahara
    • Organizer
      5th Pharmaceutical Sciences World Congress
    • Place of Presentation
      Melbourne Convention and Exhibition Centre(メルボルン)
    • Year and Date
      2014-04-13 – 2014-04-16
    • Data Source
      KAKENHI-PROJECT-24590198
  • [Presentation] 医療用医薬品を用いたGMP基準の新規遺伝子ベクターの開発

    • Author(s)
      西垣 和香、兒玉 幸修、北原 隆志、佐々木 均
    • Organizer
      日本薬剤学会第29年会
    • Place of Presentation
      大宮ソニックシティビル(大宮)
    • Year and Date
      2014-05-20 – 2014-05-22
    • Data Source
      KAKENHI-PROJECT-26293034
  • [Presentation] Effects of antiarrhythmic agents on beating rhythm of cultured cardiomyocyte networks on an agarose microchamber chip

    • Author(s)
      Ohwaki Y、Araki R、Tominaga R、Terazono H、To H、Sasaki H、Nakashima M
    • Organizer
      The Second Asian Symposium on Pharmaceutical Sciences
    • Place of Presentation
      Nagasaki,、Japan
    • Data Source
      KAKENHI-PROJECT-20590147
  • [Presentation] Dendrigraft poly-L-lysineを構成成分とした生分解型siRNAベクターの構築

    • Author(s)
      藏本 悠、兒玉 幸修、北原 隆志、佐々木 均
    • Organizer
      日本薬剤学会第29年会
    • Place of Presentation
      大宮ソニックシティビル(大宮)
    • Year and Date
      2014-05-20 – 2014-05-22
    • Data Source
      KAKENHI-PROJECT-26293034
  • [Presentation] Dendrigraft poly-L-lysineを構成成分とした生分解型siRNAベクターの構築

    • Author(s)
      藏本 悠、兒玉 幸修、北原 隆志、佐々木 均
    • Organizer
      日本薬剤学会第29年会
    • Place of Presentation
      大宮ソニックシティビル(大宮)
    • Year and Date
      2014-05-20 – 2014-05-22
    • Data Source
      KAKENHI-PROJECT-24590198
  • [Presentation] Secure and effective gene vector of polyamidoamine dendrimer pharmaceutically modified with anionic polymer

    • Author(s)
      Yukinobu Kodama, Yumi Yamashita, Takashi Kitahara, Hitoshi Sasaki
    • Organizer
      5th Pharmaceutical Sciences World Congress
    • Place of Presentation
      メルボルン(オーストラリア)
    • Year and Date
      2014-04-13 – 2014-04-16
    • Data Source
      KAKENHI-PROJECT-26293034
  • [Presentation] 医療用医薬品を用いたGMP基準の新規遺伝子ベクターの開発

    • Author(s)
      西垣 和香、兒玉 幸修、北原 隆志、佐々木 均
    • Organizer
      日本薬剤学会第29年会
    • Place of Presentation
      大宮ソニックシティビル(大宮)
    • Year and Date
      2014-05-20 – 2014-05-22
    • Data Source
      KAKENHI-PROJECT-24590198
  • [Presentation] Development of fluorescent γ-polyglutamic acid complex for sentinel lymph node imaging

    • Author(s)
      Hagimori M., Hatabe E., Sano K., Sasaki H., Saji H., Mukai T.
    • Organizer
      2014 World Molecular Imaging Congress
    • Place of Presentation
      COEX Convention Center, Seoul
    • Year and Date
      2014-09-17 – 2014-09-20
    • Data Source
      KAKENHI-PROJECT-24390294
  • [Presentation] センチネルリンパ節イメージングを目指した蛍光標識γ-ポリグルタミン酸複合体の開発

    • Author(s)
      萩森政頼, 畑辺恵里, 佐野紘平, 佐々木均, 佐治英郎, 向高弘
    • Organizer
      第9回日本分子イメージング学会学術集会
    • Place of Presentation
      千里ライフサイエンスセンター, 豊中
    • Year and Date
      2014-05-22 – 2014-05-23
    • Data Source
      KAKENHI-PROJECT-24390294
  • [Presentation] Secure and effective gene vector of polyamidoamine dendrimer pharmaceutically modified with anionic polymer

    • Author(s)
      Yukinobu Kodama, Yumi Yamashita, Takashi Kitahara, Sasaki Hitoshi
    • Organizer
      5th Pharmaceutical Sciences World Congress
    • Place of Presentation
      Melbourne Convention and Exhibition Centre(メルボルン)
    • Year and Date
      2014-04-13 – 2014-04-16
    • Data Source
      KAKENHI-PROJECT-24590198
  • 1.  NAKASHIMA Mikiro (00260737)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 11 results
  • 2.  NAKAMURA Junzo (30115901)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 16 results
  • 3.  KUROSAKI Tomoaki (00582016)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 55 results
  • 4.  TO Hideto (90346809)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 36 results
  • 5.  KAWAKAMI Shigeru (20322307)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 7 results
  • 6.  KITAHARA Takashi (30380934)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 42 results
  • 7.  KODAMA Yukinobu (50448510)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 27 results
  • 8.  MUKAI Takahiro (30284706)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 7 results
  • 9.  NISHIDA Koyo (20237704)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 8 results
  • 10.  NAKASHIMA Mihoko (00301367)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 11.  TANAKA Masafumi (40411904)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  KAWAKAMI Atsushi (90325639)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  SAKAEDA Toshiyuki (00304098)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  太田 伸生 (10143611)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 15.  平山 謙二 (60189868)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 16.  濱野 真二郎 (70294915)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  新留 琢郎 (26204210)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  岩本 直樹 (80437897)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  一瀬 邦弘 (60437895)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  古賀 智裕 (90537284)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  右田 清志 (60264214)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  中村 英樹 (10437832)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  朝比奈 泉 (30221039)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  小守 壽文 (00252677)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  住田 吉慶 (50456654)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  鎌倉 慎治 (80224640)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  三浦 桂一郎 (10634446)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  中村 忠博 (60882199)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  山下 親正 (30622188)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  室 高広 (10832834)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  SHIMADA Takashi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  NAGATSUKA Shin-Ichiro
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  TACHIKI Hidehisa
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  FUMOTO Shintaro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 35.  KUMAGAI Takashi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 36.  菊池 三穂子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 37.  坂口 美亜子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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