SASAKI Hitoshi 佐々木均

… Alternative Names

佐々木均ササキヒトシ

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Researcher Number	00170689
Other IDs
Affiliation (Current)	2025: 長崎大学, 熱帯医学研究所, 特命教授
Affiliation (based on the past Project Information) *help	2021 – 2023: 長崎大学, 熱帯医学研究所, 特命教授 2014 – 2021: 長崎大学, 病院(医学系), 教授 2011 – 2014: 長崎大学, 大学病院, 教授 2009 – 2011: Nagasaki University, 病院, 教授 2010: 長崎大学, 長崎大学病院・薬剤部, 教授 … More 2003 – 2008: 長崎大学, 医学部・歯学部附属病院, 教授 2000: Department of Hospital Pharmacy Nagasaki University School of Medicine Professor, 医学部・附属病院, 教授 1998 – 1999: 長崎大学, 医学部・附属病院, 助教授 1997: 長崎大学, 医学部附属病院, 助教授 1994: 長崎大学, 薬学部, 助教授 Less
Review Section/Research Field	Principal Investigator Medical pharmacy / Basic Section 47060:Clinical pharmacy-related / 医薬分子機能学 / Ophthalmology / Physical pharmacy Except Principal Investigator Medical pharmacy / Physical pharmacy / Surgical dentistry / Basic Section 90120:Biomaterials-related / Collagenous pathology/Allergology / Radiation science
Keywords	Principal Investigator 遺伝子デリバリー / 遺伝子治療 / 遺伝子 / 速度論 / 薬物送達 / 眼 / 感染症 / γ-polyglutamic acid / ナノ微粒子 / Drug delivery system … More / ドラッグデリバリー / ナノ粒子 / 微粒子 / mRNA / ｍRNA / ワクチン / ドラッグデリバリーシステム / 核酸医薬 / Clinical application / Pharmacokinetics / Ophthalmology / Polymer / Liposomes / Gene delivery / Topical application / ベクター / 動態 / 局所 / 臨床応用 / 薬物速度論 / 眼科 / 高分子 / リポソーム / 局所適用 / ADEQUATE MEDICATION-USE / DRUG DISPOSITION / DIFFUSION / PHARMACOKINETICS / MEMBRANE PENETRATION / PHARMACOTHERAPY / DRUG DELIVERY / EYE / 適正化 / 薬物動態 / 拡散 / 膜透過 / 薬物治療 / ナノデバイス / 核酸 / DNAワクチン / シャーガス病 / 住血吸虫症 / マラリア / 顧みられない熱帯病 / 遺伝子ベクター / 加齢黄斑変性症 / chondroitin sulfate / アニオン性高分子 / 遺伝子導入 / カチオン性遺伝子ベクター / 低分子リガンド / 静電的相互作用 / 遺伝子導入技術 / 自己組織化 / 生体分解型ベクター / 生体適合型ベクター / グリチルリチン / 葉酸 / ナノ材料 / 癌 / 遣伝子治療 / 遣伝子 / ガラクトサミン / 薬剤性肝炎モデル / ウイルス性肝炎モデル / カチオン性リポソーム / 肝切除 / 肝炎 / カチオン性高分子 / 肝臓 / 疾病 / デリバリー … More Except Principal Investigator CMC / 後発医薬品 / 薬物送達 / 自己組織化デバイス / 基質 / 遺伝子送達デバイス / 遺伝子導入担体 / 遺伝子活性化基質 / 遺伝子治療 / 人工骨基質 / ベクター / 遺伝子 / 骨再生 / siRNA / ドラッグデリバリーシステム / 肝線維症 / 核酸医薬品 / ナノ粒子 / Ｔ-ＬＥＸ / T-LEX / トキシコゲノミクス / 製剤品質評価 / ファーマコビジランス / ヒト肝キメラマウス / 薬剤性肝障害 / 関節超音波 / アレイ解析 / リバースシグナル / CTLA-4Ig / ACPA-サブクラス / 滑膜線維芽細胞 / サイトカイン・ケモカイン / ACPA / 骨破壊 / 破骨細胞 / M1・M2 / 単球 / バイオマーカー / CTLA-4-Ig / 関節リウマチ / Viscous dosage form / Drug delivery system / Rat / Phenol red / Liver surface application / Drug targeting / Liver / 微量連続投与 / 単回投与 / 粘性製剤 / DDS / ラット / phenol red / 肝臓表面投与 / 肝臓 / メラノーマ / 遺伝子デリバリー / マラリア / ナノデバイス / DNAワクチン / 感染症 / 癌 / ナノ材料 / ワクチン / イメージング / ナノバイオ / 放射線 / 薬学 / 薬剤反応性 / 薬剤仮応性 / 動物実験 / セロミクス / 薬剤応答性 / 毒性試験 / 品質試験 / 安全性学 / 医薬品情報 / アミノ酸抱合体 / サリチル酸 / プロドラッグ / 代謝 / 腸内細菌 Less

Development of nucleic acid vaccine for mucosal-application based on pharmaceutics and immunology -For Covid-19 prevention-Principal Investigator
- Principal Investigator
  
  Sasaki Hitoshi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Nagasaki University
Development of a novel therapeutic method for liver fibrosis by introducing siRNA using a liver-targeted ternary complex
- Principal Investigator
  
  Kurosaki Tomoaki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  Nagasaki University
Development of new nucleic acid medicines for intractable respiratory diseasesPrincipal Investigator
- Principal Investigator
  
  SASAKI Hitoshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Nagasaki University
Gene activated-matrix comprised of self-assemble and multi-functional nano-devise facilitates the bone engineering
- Principal Investigator
  
  Asahina Izumi
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Surgical dentistry
- Research Institution
  Nagasaki University
Basic research for searching of new therapeutic targets of rheumatoid arthritis through investigation of novel action of CTLA-4-Ig
- Principal Investigator
  
  KAWAKAMI Atsushi
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Nagasaki University
Development of the novel technique intended to the prophylaxis and treatment of neglected tropical diseasesPrincipal Investigator
- Principal Investigator
  
  SASAKI Hitoshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Nagasaki University
Study of risk assessment of drug-induced liver injury using chimeric mice with highly humanized liver and large-scale adverse drug reactions databese
- Principal Investigator
  
  NAKASHIMA Mikiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Nagasaki University
Development of self-assembling nanodevices for multimodal molecular imaging
- Principal Investigator
  
  MUKAI Takahiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Kobe Pharmaceutical University
Development of safety vaccine using spleen- and dendritice cells-targeted nano device
- Principal Investigator
  
  KITAHARA Takashi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Nagasaki University
Development of novel gene therapy targeting age-related macular degenerationPrincipal Investigator
- Principal Investigator
  
  SASAKI Hitoshi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Ophthalmology
- Research Institution
  Nagasaki University
The development of self-assembly nano-devices based on electrostatic interaction and the application to selective drug deliveryPrincipal Investigator
- Principal Investigator
  
  SASAKI Hitoshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Nagasaki University
Study on evaluation system for drug cardiotoxicity using on-chip cell-besed analysis and quality examination of generic products of injection
- Principal Investigator
  
  NAKASHIMA Mikiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Nagasaki University
Influence of disease stage and pharmacotherapy on gene deliveryPrincipal Investigator
- Principal Investigator
  
  SASAKI Hitoshi
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Nagasaki University
Development of topical gene delivery system for clinical applicationPrincipal Investigator
- Principal Investigator
  
  SASAKI Hitoshi
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Nagasaki University Hospital of Medicine and Dentistry
Development of dosage form for the application to the liver surface for targeting of drug in the liver
- Principal Investigator
  
  NAKAMURA Junzo
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Nagasaki University
PHARMACOKINETIC ANALYSIS FOR ADEQUATE MEDICATION-USE IN OPHTHALMOLOGYPrincipal Investigator
- Principal Investigator
  
  SASAKI Hitoshi
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  医薬分子機能学
- Research Institution
  NAGASAKI UNIVERSITY HOSPITAL, SCHOOL OF MEDICINE
腸内細菌による代謝を利用した大腸への選択的薬物送達に関する研究
- Principal Investigator
  
  NAKAMURA Junzo
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Nagasaki University

[Journal Article] Gene-Activated Matrix with Self-Assembly Anionic Nano-Device Containing Plasmid DNAs for Rat Cranial Bone Augmentation2021
- Author(s)
  Masahito Hara,Yoshinori Sumita,Yukinobu Kodama,Mayumi Iwatake, Hideyuki Yamamoto,Rena Shido,Shun Narahara,Takunori Ogaeri,Hitoshi Sasaki and Izumi Asahina
- Journal Title
  
  Materials
  
  Volume: 14 Issue: 22 Pages: 22-22
- DOI
  10.3390/ma14227097
- NAID
  120007186847
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K23059, KAKENHI-PROJECT-17H01604, KAKENHI-PROJECT-20K10010
[Journal Article] Delivery of pDNA to the Lung by Lipopolyplexes Using N-Lauroylsarcosine and Effect on the Pulmonary Fibrosis2021
- Author(s)
  Kurosaki T, Kanda H, Hashizume J, Sato K, Harasawa H, Nakamura T, Sasaki H, Kodama Y.
- Journal Title
  
  Pharmaceutics
  
  Volume: 13 Issue: 11 Pages: 1983-1983
- DOI
  10.3390/pharmaceutics13111983
- NAID
  120007188604
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07156, KAKENHI-PROJECT-20K12649
[Journal Article] Anionic Complex with Efficient Expression and Good Safety Profile for mRNA Delivery2021
- Author(s)
  Hamada E, Kurosaki T, Hashizume J, Harasawa H, Nakagawa H, Nakamura T, Kodama Y, Sasaki H.
- Journal Title
  
  Pharmaceutics
  
  Volume: 13 Issue: 1 Pages: 126-126
- DOI
  10.3390/pharmaceutics13010126
- NAID
  120006961264
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07156, KAKENHI-PROJECT-18H02589
[Journal Article] Development of a DNA Vaccine for Melanoma Metastasis by Inhalation Based on an Analysis of Transgene Expression Characteristics of Naked pDNA and a Ternary Complex in Mouse Lung Tissues2020
- Author(s)
  Kodama Y, Nakashima M, Nagahara T, Oyama N, Hashizume J, Nakagawa H, Harasawa H, Muro T, Kurosaki T, Yamashita C, Hashida M, Kitahara T, Sasaki H, Kawakami S, Nakamura T
- Journal Title
  
  Pharmaceutics
  
  Volume: 12 Issue: 6 Pages: 540-540
- DOI
  10.3390/pharmaceutics12060540
- NAID
  120006988149
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07156, KAKENHI-PROJECT-18H02589
[Journal Article] Proliferation‐associated long noncoding RNA, TMPO‐AS1 , is a potential therapeutic target for triple‐negative breast cancer2020
- Author(s)
  Mitobe Yuichi、Ikeda Kazuhiro、Sato Wataru、Kodama Yukinobu、Naito Mitsuru、Gotoh Noriko、Miyata Kanjiro、Kataoka Kazunori、Sasaki Hitoshi、Horie‐Inoue Kuniko、Inoue Satoshi
- Journal Title
  
  Cancer Science
  
  Volume: 1 Issue: 7 Pages: 1-20
- DOI
  10.1111/cas.14498
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22557, KAKENHI-PROJECT-17H04205, KAKENHI-PROJECT-20K08916, KAKENHI-PROJECT-20K21636, KAKENHI-PROJECT-18H02589, KAKENHI-PROJECT-18H02679, KAKENHI-PROJECT-20H03734, KAKENHI-PROJECT-18K18379
[Journal Article] Splenic Delivery System of pDNA through Complexes Electrostatically Constructed with Protamine and Chondroitin Sulfate2018
- Author(s)
  Kodama Y, Nishigaki W, Nakamura T, Fumoto S, Nishida K, Kurosaki T, Nakagawa H, Kitahara T, Muro T, Sasaki H.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 41 Issue: 3 Pages: 342-349
- DOI
  10.1248/bpb.b17-00667
- NAID
  130006407447
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02589
[Journal Article] Methotrexate-Coated Complexes of Plasmid DNA and Polyethylenimine for Gene Delivery2018
- Author(s)
  Kodama Y, Nishigaki W, Nakamura T, Fumoto S, Nishida K, Kurosaki T, Nakagawa H, Kitahara T, Muro T, Sasaki H.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 41 Issue: 10 Pages: 1537-1542
- DOI
  10.1248/bpb.b18-00144
- NAID
  130007494219
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2018-10-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08449, KAKENHI-PROJECT-18H02589
[Journal Article] Gene delivery system of pDNA using the blood glycoprotein fetuin.2018
- Author(s)
  Kodama Y, Hanamura H, Muro T, Nakagawa H, Kurosaki T, Nakamura T, Kitahara T, Kawakami S, Nakashima M, Sasaki H.
- Journal Title
  
  Journal of Drug Targeting
  
  Volume: 印刷中 Issue: 7 Pages: 604-609
- DOI
  10.1080/1061186x.2017.1405425
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08449, KAKENHI-PROJECT-18H02589
[Journal Article] Application of biodegradable dendrigraft poly-l-lysine to a small interfering RNA delivery system.2017
- Author(s)
  Kodama Y, Kuramoto H, Mieda Y, Muro T, Nakagawa H, Kurosaki T, Sakaguchi M, Nakamura T, Kitahara T, Sasaki H.
- Journal Title
  
  Journal of Drug Targeting
  
  Volume: 25 Issue: 1 Pages: 49-57
- DOI
  10.1080/1061186x.2016.1184670
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26293034, KAKENHI-PROJECT-26860107, KAKENHI-PROJECT-15K08444
[Journal Article] Splenic gene delivery system using self-assembling nano-complex with phosphatidylserine analog.2015
- Author(s)
  Kurosaki T, Nakasone C, Kodama Y, Egashira K, Harasawa H, Muro T, Nakagawa H, Kitahara T, Higuchi N, Nakamura T, Sasaki H.
- Journal Title
  
  Biol Pharm Bull.
  
  Volume: 38 Pages: 23-29
- NAID
  130004872233
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26293034
[Journal Article] Splenic gene delivery system using self-assembling nano-complex with phosphatidylserine analog.2015
- Author(s)
  Kurosaki T, Nakasone C, Kodama Y, Egashira K, Harasawa H, Muro T, Nakagawa H, Kitahara T, Higuchi N, Nakamura T, Sasaki H.
- Journal Title
  
  Biol Pharm Bull.
  
  Volume: 38 Pages: 23-29
- NAID
  130004872233
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590198
[Journal Article] Secure and effective gene delivery system of plasmid DNA coated by polynucleotide.2015
- Author(s)
  Kodama Y, Ohkubo C, Kurosaki T, Egashira K, Sato K, Fumoto S, Nishida K, Higuchi N, Kitahara T, Nakamura T, Sasaki H.
- Journal Title
  
  J Drug Target.
  
  Volume: 23 Issue: 1 Pages: 43-51
- DOI
  10.3109/1061186x.2014.950665
- NAID
  120006986293
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590198, KAKENHI-PROJECT-25350553, KAKENHI-PROJECT-26293034, KAKENHI-PROJECT-26860107
[Journal Article] Immunogenicity and anti-fecundity effect of nanoparticle coated glutathione S-transferase (SjGST) DNA vaccine against murine Schistosoma japonicum infection.2015
- Author(s)
  Mbanefo EC, Kumagai T, Kodama Y, Kurosaki T, Furushima-Shimogawara R, Cherif MS, Mizukami S, Kikuchi M, Huy NT, Ohta N, Sasaki H, Hirayama K.
- Journal Title
  
  Parasitol Int.
  
  Volume: 64 Issue: 4 Pages: 24-31
- DOI
  10.1016/j.parint.2015.01.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590503, KAKENHI-PROJECT-26293034, KAKENHI-PROJECT-26860107, KAKENHI-PROJECT-15K08445, KAKENHI-PROJECT-15H05278, KAKENHI-PROJECT-26670198, KAKENHI-PROJECT-25293099
[Journal Article] Quaternary complexes modified from pDNA and poly-l-lysine complexes to enhance pH-buffering effect and suppress cytotoxicity.2015
- Author(s)
  Kodama Y, Yatsugi Y, Kitahara T, Kurosaki T, Egashira K, Nakashima M, Muro T, Nakagawa H, Higuchi N, Nakamura T, Sasaki H.
- Journal Title
  
  Journal of Pharmaceutical Sciences
  
  Volume: 104 Issue: 4 Pages: 1470-1477
- DOI
  10.1002/jps.24364
- NAID
  120006987163
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26860107, KAKENHI-PROJECT-26293034
[Journal Article] Novel siRNA delivery system using a ternary polymer complex with strong silencing effect and no cytotoxicity.2014
- Author(s)
  Kodama Y, Shiokawa Y, Nakamura T, Kurosaki T, Aki K, Nakagawa H, Muro T, Kitahara T, Higuchi N, Sasaki H.
- Journal Title
  
  Biol Pharm Bull
  
  Volume: 37 Pages: 1274-1281
- NAID
  130004677533
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590198
[Journal Article] Novel siRNA delivery system using a ternary polymer complex with strong silencing effect and no cytotoxicity.2014
- Author(s)
  Kodama Y, Shiokawa Y, Nakamura T, Kurosaki T, Aki K, Nakagawa H, Muro T, Kitahara T, Higuchi N, Sasaki H.
- Journal Title
  
  Biol Pharm Bull.
  
  Volume: 37 Pages: 1274-1281
- NAID
  130004677533
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26293034
[Journal Article] Biodegradable nanoparticles composed of dendrigraft poly-L-lysine for gene delivery.2014
- Author(s)
  Kodama Y, Nakamura T, Kurosaki T, Egashira K, Mine T, Nakagawa H, Muro T, Kitahara T, Higuchi N, Sasaki H.
- Journal Title
  
  Eur J Pharm Biopharm.
  
  Volume: 87 Issue: 3 Pages: 472-479
- DOI
  10.1016/j.ejpb.2014.04.013
- NAID
  120006986334
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590198, KAKENHI-PROJECT-26293034, KAKENHI-PROJECT-26860107
[Journal Article] Radiolabeled γ-polyglutamic acid complex as a nano-platform for sentinel lymph node imaging2014
- Author(s)
  Kohei Sano, Yuriko Iwamiya, Tomoaki Kurosaki, Mikako Ogawa, Yasuhiro Magata, Hitoshi Sasaki, Takashi Ohshim, Minoru Maeda, Takahiro Mukai
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 194 Pages: 310-315
- DOI
  10.1016/j.jconrel.2014.08.025
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390294
[Journal Article] Secure splenic delivery of plasmid DNA and its application to DNA vaccine.2013
- Author(s)
  Kurosaki T, Kodama Y, Muro T, Higuchi N, Nakamura T, Kitahara T, Miyakoda M, Yui K, Sasaki H.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 36 Pages: 1800-1806
- NAID
  130003382044
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590198
[Journal Article] Ternary complex of plasmid DNA with protamine and γ-polyglutamic acid for biocompatible gene delivery system2013
- Author(s)
  Kanda K, Kodama Y, Kurosaki T, Imamura M, Nakagawa H, Muro T, Higuchi N, Nakamura T, Kitahara T, Honda M, Sasaki H
- Journal Title
  
  Biol Pharm Bull
  
  Volume: 36(11) Pages: 1794-9
- NAID
  130003382043
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659813
[Journal Article] Ocular gene delivery systems using ternary complexes of plasmid DNA, polyethylenimine, and anionic polymers2013
- Author(s)
  Kurosaki T, Uematsu M, Shimoda K, Suzuma K, Nakai M, Nakamura T, Kitahara T, Kitaoka T, Sasaki H
- Journal Title
  
  Biol Pharm Bull
  
  Volume: 36(1) Pages: 96-101
- NAID
  130003361352
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659813
[Journal Article] Secure splenic delivery of plasmid DNA and its application to DNA vaccine2013
- Author(s)
  Kurosaki T, Kodama Y, Muro T, Higuchi N, Nakamura T, Kitahara T, Miyakoda M, Yui K, Sasaki H
- Journal Title
  
  Biol Pharm Bull
  
  Volume: 36(11) Pages: 1800-6
- NAID
  130003382044
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659813
[Journal Article] Ocular Gene Delivery Systems Using Ternary Complexes of Plasmid DNA, Polyethylenimine, and Anionic Polymers2013
- Author(s)
  Kurosaki T, Uematsu M, Shimoda K, Suzuma K, Nakai M, Nakamura T, Kitahara T, Kitaoka T, Sasaki H.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 36 Issue: 1 Pages: 96-101
- DOI
  10.1248/bpb.b12-00728
- NAID
  130003361352
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659813
[Journal Article] Ternary Complex of Plasmid DNA with Protamine and γ-Polyglutamic Acid for Biocompatible Gene Delivery System2013
- Author(s)
  Kosuke Kanda, Yukinobu Kodama, Tomoaki Kurosaki, Masanobu Imamura, Hiroo Nakagawa, Takahiro Muro, Norihide Higuchi, Tadahiro Nakamura, Takashi Kitahara, Masayuki Honda, Hitoshi Sasaki
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 36 Pages: 1794-1799
- NAID
  130003382043
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659813
[Journal Article] Self-assemble gene delivery system for molecular targeting using nucleic acid aptamer2012
- Author(s)
  Kurosaki T, Higuchi N, Kawakami S, Higuchi Y, Nakamura T, Kitahara T, Hashida M, Sasaki H
- Journal Title
  
  Gene
  
  Volume: 491(2) Pages: 205-9
- NAID
  120006985259
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659813
[Journal Article] Immunogenicity of novel nanoparticle-coated MSP-1 C-terminus malaria DNA vaccine using different routes of administration2011
- Author(s)
  Cherif MS, Shuaibu MN, Kurosaki T, Helegbe GK, Kikuchi M, Yanagi T, Tsuboi T, Sasaki H, Hirayama K.
- Journal Title
  
  Vaccine
  
  Volume: 29(48) Pages: 9038-9050
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390010
[Journal Article] Secure and effective gene vector of polyamidoamine dendrimer pharmaceutically modified with anionic polymer2011
- Author(s)
  Kurosaki T, Yamashita Y, Aki K, Harasawa H, Nakagawa H, Kodama Y, Higuchi N, Nakamura T, Kitahara T, Sasaki H
- Journal Title
  
  J Pharm Sci
  
  Volume: 100(11) Pages: 4855-4863
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390010
[Journal Article] Secure and effective gene vector of polyamidoamine dendrimer pharmaceutically modified with anionic polymer2011
- Author(s)
  Kurosaki T, Yamashita Y, Aki K, Harasawa H, Nakagawa H, Kodama Y, Higuchi N, Nakamura T, Kitahara T, Sasaki H
- Journal Title
  
  J Pharm Sci
  
  Volume: 100(11) Pages: 4855-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659813
[Journal Article] Immunogenicity of novel nanoparticle-coated MSP-1 C-terminus malaria DNA vaccine using different routes of administration2011
- Author(s)
  Cherif MS, Shuaibu MN, Kurosaki T, Helegbe GK, Kikuchi M, Yanagi T, Tsuboi T, Sasaki H, Hirayama K
- Journal Title
  
  Vaccine
  
  Volume: 29 Pages: 9038-9050
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390010
[Journal Article] Nanoparticles electrostatically coated with folic acid for effective gene therapy2011
- Author(s)
  Kurosaki T, Morishita T, Kodama Y, Sato K, Nakagawa H, Higuchi N, Nakamura T, Hamamoto T, Sasaki H, Kitahara T
- Journal Title
  
  Mol Pharm
  
  Volume: 8(3) Pages: 913-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659813
[Journal Article] Nanoparticles electrostatically coated with folic acid for effective gene therapy2011
- Author(s)
  Kurosaki T, Morishita T, Kodama Y, Sato K, Nakagawa H, Higuchi N, Nakamura T, Hamamoto T, Sasaki H, Kitahara T
- Journal Title
  
  Mol Pharm
  
  Volume: 8(3) Pages: 913-919
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390010
[Journal Article] Secure and effective gene vector of polyamidoamine dendrimer pharraac eutically modified with anionic polymer2011
- Author(s)
  Kurosaki T, Yamashita Y, Aki K, Harasawa H, Nakagawa H, Kodama Y, Higuchi N, Nakamura T, Kitahara T, Sasaki H
- Journal Title
  
  J Pharm Sci
  
  Volume: 100 Issue: 11 Pages: 4855-4863
- DOI
  10.1002/jps.22701
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390010
[Journal Article] Gamma-polyglutamic acid-coated vectors for effective and safe gene therapy2010
- Author(s)
  Kurosaki T, Kitahara T, Kawakami S, Higuchi Y, Yamaguchi A, Nakagawa H, Kodama Y, Hamamoto T, Hashida M, Sasaki H
- Journal Title
  
  J Control Release
  
  Volume: 142(3) Pages: 404-410
- NAID
  120006984597
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390010
[Journal Article] Gamma-polyglutamic acid-coated vectors for effective and safe gene therapy.2010
- Author(s)
  Kurosaki T, Kitahara T, Kawakami S, Higuchi Y, Yamaguchi A, Nakagawa H, Kodama Y, Hamamoto T, Hashida M, Sasaki H.
- Journal Title
  
  J Control Release.
  
  Volume: 142 Pages: 404-410
- NAID
  120006984597
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390010
[Journal Article] Chondroitin sulfate capsule system for efficient and secure gene delivery2010
- Author(s)
  Kurosaki T, Kitahara T, Fumoto S, Nishida K, Yamamoto K, Nakagawa H, Kodama Y, Higuchi N, Nakamura T, Sasaki H
- Journal Title
  
  J Pharm Pharm Sci
  
  Volume: 13(3) Pages: 351-361
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390010
[Journal Article] Chondroitin sulfate capsule system for efficient and secure gene delivery.2010
- Author(s)
  Kurosaki T, Kitahara T, Fumoto S, Nishida K, Yamamoto K, Nakagawa H, Kodama Y, Higuchi N, Nakamura T, Sasaki H.
- Journal Title
  
  J Pharm Pharm Sci
  
  Volume: 13 Pages: 351-361
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390010
[Journal Article] Pulmonary gene delivery of hybrid vector, lipopolyplex containing N-lauroylsarcosine, via the systemic route2009
- Author(s)
  Kurosaki T, Kishikawa R, Matsumoto M, Kodama Y, Hamamoto T, To H, Niidome T, Takayama K, Kitahara T, Sasaki H
- Journal Title
  
  J Control Release
  
  Volume: 136(3) Pages: 213-219
- NAID
  120006984134
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390010
[Journal Article] Ternary complexes of pDNA, polyethylenimine, and gamma-polyglutamic acid for gene delivery systems.2009
- Author(s)
  Kurosaki, T., Kitahara, T., Fumoto, S., Nishida, K., Nakamura, J., Niidome, T., Kodama, Y., Nakagawa, H., To, H., Sasaki, H.
- Journal Title
  
  Biomaterials 30
  
  Pages: 2846-2853
- NAID
  120006982935
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390010
[Journal Article] Cationic liposomes-mediated plasmid DNA delivery in murine hepatitis induced by carbon tetrachloride.2009
- Author(s)
  Yoshioka, T, Yoshida, S., Kurosaki, T., Teshima, M., Nishida, K., Nakamura, J., Nakashima, M., To, H., Kitahara, T., Sasaki, H.
- Journal Title
  
  J.Liposome Res. 23
  
  Pages: 1-7
- NAID
  120006984575
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390010
[Journal Article] The development of a gene vector electrostatically assembled with a polysaccharide capsule.2009
- Author(s)
  Kurosaki, T, Kitahara, T., Kawakami, S., Nishida, K., Nakamura, J., Teshima, M., Nakagawa, H., Kodama, Y., To, H., Sasaki, H.
- Journal Title
  
  Biomaterials 30
  
  Pages: 4427-4434
- NAID
  120006984133
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390010
[Journal Article] Ternary complexes of pDNA, polyethylenimine, and gamma-polyglutamic acid for gene delivery systems2009
- Author(s)
  Kurosaki T, Kitahara T, Fumoto S, Nishida K, Nakamura J, Niidome T, Kodama Y, Nakagawa H, To H, Sasaki H
- Journal Title
  
  Biomaterials
  
  Volume: 30(14) Pages: 2846-2853
- NAID
  120006982935
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390010
[Journal Article] Pulmonary gene delivery of hybrid vector, lipopolyplex containing N-lauroylsarcosine, via the systemic route.2009
- Author(s)
  Kurosaki, T., Kishikawa, R., Matsumoto, M., Kodama, Y., Hamamoto, T., To, H., Niidome, T., Takayama, K., Kitahara, T., Sasaki, H.
- Journal Title
  
  J.Control. Release 136
  
  Pages: 213-219
- NAID
  120006984134
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390010
[Journal Article] Cationic liposomes-mediated plasmid DNA delivery in murine hepatitis induced by carbon tetrachloride2009
- Author(s)
  Yoshioka T, Yoshida S, Kurosaki T, Teshima M, Nishida K, Nakamura J, Nakashima M, To H, Kitahara T, Sasaki H
- Journal Title
  
  J Liposome Res 23
  
  Pages: 1-7
- NAID
  120006984575
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590143
[Journal Article] Cationic liposomes-mediated plasmid DNA delivery in murine hepatitis induced by carbon tetrachloride2009
- Author(s)
  Yoshioka T, Yoshida S, Kurosaki T, Teshima M, Nishida K, Nakamura J, Nakashima M, To H, Kitahara T, Sasaki H
- Journal Title
  
  J Liposome Res
  
  Volume: 19(2) Pages: 141-147
- NAID
  120006984575
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390010
[Journal Article] The development of a gene vector electrostatically assembled with a polysaccharide capsule2009
- Author(s)
  Kurosaki T, Kitahara T, Kawakami S, Nishida K, Nakamura J, Teshima M, Nakagawa H, Kodama Y, To H, Sasaki H
- Journal Title
  
  Biomaterials
  
  Volume: 30(26) Pages: 4427-4434
- NAID
  120006984133
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390010
[Journal Article] Influence of murine hepatitis induced by D-(+)-galactosamine hydrochloride and lipopolysaccharide on gene expression of polyethylenimine/plasmid DNA polyplex2008
- Author(s)
  Miyanaga K, Yoshioka T, Nakagawa H, Kitahara T, To H, Ichikawa N, Nakashima M, Nishida K, Nakamura J, Sasaki H
- Journal Title
  
  Biol Pharm Bull 31
  
  Pages: 1585-9
- NAID
  110006839022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590143
[Journal Article] オンチップ心筋拍動細胞ネットワークを用いた抗不整脈薬の薬物応答性の解析2008
- Author(s)
  中嶋幹郎、大脇裕一、向江俊彦、梅野繁智、柳原克紀、河野茂、冨永留美、荒木良介、寺薗英之、北原隆志、藤秀人、佐々木均
- Journal Title
  
  長崎医学会雑誌 83
  
  Pages: 59-66
- NAID
  110007148533
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590147
[Journal Article] Spleen-selective gene transfer following the administration of naked plasmid DNA onto the spleen surface in mice2007
- Author(s)
  J.Nakamura, S.Fumoto, R.Kawanami, H.Sasaki, et. al.
- Journal Title
  
  Biol.Pharm.Bull. 30
  
  Pages: 941-945
- NAID
  110006273294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590143
[Journal Article] Evaluation of enhanced peritoneum permeability in methylglyoxal-treated rats as a diagnostic method for peritoneal damage2007
- Author(s)
  S.Fumoto, Y.Nakashima, K.Nishida, H.Sasaki, et. al.
- Journal Title
  
  Pharmaceutical Research 24
  
  Pages: 1891-1896
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590143
[Journal Article] Unilateral lung-selective gene transfer following the administration of Naked plasmid DNA onto the pulmonary pleural surface in mice2007
- Author(s)
  J.Nakamura, S.Fumoto, K.Ariyoshi, H.Sasaki, et. al.
- Journal Title
  
  Biol.Pharm.Bull. 30
  
  Pages: 729-732
- NAID
  110006271214
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590143
[Journal Article] PEGylated liposomes loading palmitoyl prednisolone for prolonged blood concentration of prednisolone2006
- Author(s)
  M.Teshima, S.Kawakami, S.Fumoto, K.Nishida, H.Sasaki
- Journal Title
  
  Biol.Pharm.Bull. 29
  
  Pages: 1436-1440
- NAID
  110005602317
- Data Source
  KAKENHI-PROJECT-18590143
[Journal Article] Partial hepatectomy enhances polyethylenimine-mediated plasmid DNA delivery2006
- Author(s)
  Y.Tada, T.Kitahara, T.Yoshioka, T.Nakamura, H.Sasaki
- Journal Title
  
  Biol.Pharm.Bull. 29
  
  Pages: 1712-1716
- NAID
  110005664015
- Data Source
  KAKENHI-PROJECT-18590143
[Journal Article] Influence of disease stage on polyethylenimine-mediated plasmid DNA delivery in murine hepatitis2006
- Author(s)
  Sasaki H, Yoshida S, Kitahara T, Yoshioka T, Nakagawa H, Nakamura T, Ichikawa N, Nishida K, Nakamura J, Nakashima M
- Journal Title
  
  Int J Pharm 318
  
  Pages: 139-45
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590143
[Journal Article] Stomach-selective gene transfer following the administration of naked plasmid DNA onto the gastric serosal surface in mice2006
- Author(s)
  J.Nakamura, S.Fumoto, K.Shoji, Y.Kodama, H.Sasaki
- Journal Title
  
  Biol.Pharm.Bull. 29
  
  Pages: 2082-2086
- NAID
  110004810296
- Data Source
  KAKENHI-PROJECT-18590143
[Journal Article] Partial hepatectomy enhances polyethylenimine-mediated plasmid DNA delivery2006
- Author(s)
  Tada Y, Kitahara T, Yoshioka T, Nakamura T, Ichikawa N, Nakashima M, Nishida K, Nakamura J, Sasaki H
- Journal Title
  
  Biol Pharm Bull 29
  
  Pages: 1712-6
- NAID
  110005664015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590143
[Journal Article] In vitro activity of lauric acid or myristylamine in combination with six antimicrobial agents against MRSA2006
- Author(s)
  T.Kitahara, Y.Aoyama, Y.Hirakata, S.Kanmihira, H.Sasaki
- Journal Title
  
  Int.J.Antimicrob.Agents 27
  
  Pages: 51-57
- Data Source
  KAKENHI-PROJECT-18590143
[Journal Article] Influence of disease stage on polyethyleniine-mediated plasmid DNA delivery in murine fepatitis2006
- Author(s)
  H.Sasaki, S.Yoshida, T.Kitahara, T.Yoshioka, H.Nakagawa
- Journal Title
  
  Inter.J.Pharmaceu 318
  
  Pages: 139-145
- Data Source
  KAKENHI-PROJECT-18590143
[Journal Article] Prolonged blood concentrationof prednisolone after intravenous injection of liposomal palmitoyl prednisolone2006
- Author(s)
  M.Teshima, S.Fumoto, K.Nishida, J.Nakamura, H.Sasaki
- Journal Title
  
  J.Control.Release 112
  
  Pages: 320-328
- Data Source
  KAKENHI-PROJECT-18590143
[Journal Article] Self-association properties of 4-[1-hydroxy-1-methylethyl]-2-propyl-1-[4-[2 [tetrazole-5-yl]phenyl]phenyl]methylimidazole-5-carboxylic acid monohydrate (CS-088), an antiglaucoma opthalmic agent2005
- Author(s)
  T.Kikuchi, K.Ito, M.Suzuki, A.Kusai, K.Iseki, H.Sasaki
- Journal Title
  
  Int. J. Pharmaceu. 290
  
  Pages: 100-106
- Data Source
  KAKENHI-PROJECT-15590133
[Journal Article] Effect of solution composition of plasmid DNA on gene transfection following liver surface administration in mice.2005
- Author(s)
  R.Hirayama, S.Fumoto, K.Nishida, M.Nakashima, H.Sasaki, J.Nakamura
- Journal Title
  
  Biol. Pharm. Bull. 28
  
  Pages: 2166-2169
- NAID
  110003666420
- Data Source
  KAKENHI-PROJECT-15590133
[Journal Article] Effect of solution composition of plasmid DNA on gene transfection following liver surface administration in mice2005
- Author(s)
  Ryu Hirayama, Hitoshi Sasaki, Junzo Nakamura et al.
- Journal Title
  
  Biological & Pharmaceutical Bulletin 28・11
  
  Pages: 2166-2169
- NAID
  110003666420
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590133
[Journal Article] Unilateral kidney-selective gene transfer following the administration of naked plasmid DNA to the kidney surface in mice.2005
- Author(s)
  R.Hirayama, K.Nishida, S.Fumoto, M, Nakashima, H.Sasaki, J.Nakamura
- Journal Title
  
  Biol. Pharm. Bull. 28
  
  Pages: 181-184
- NAID
  110003665796
- Data Source
  KAKENHI-PROJECT-15590133
[Journal Article] Unilateral kidney-selective gene transfer following the administration of naked plasmid DNA to the kidney surface in mice2005
- Author(s)
  Mikiro Nakashima, Hitoshi Sasaki, Junzo Nakamura et al.
- Journal Title
  
  Biological & Pharmaceutical Bulletin 28
  
  Pages: 181-184
- NAID
  110003665796
- Data Source
  KAKENHI-PROJECT-15590133
[Journal Article] Delivery advantage to the unilateral kedney by direct drug application to the kidney surface in rats and pharmacokinetic verification based on a physiological model.2005
- Author(s)
  K.Nishida, M, Kamenosono, A, Kuma, S.Fumoto, T.Mukai, M.Nakashima, H.Sasaki, J.Nakamura
- Journal Title
  
  Journal of Drug Targeting 13
  
  Pages: 215-223
- Data Source
  KAKENHI-PROJECT-15590133
[Journal Article] Unilateral kindney-selective gene transfer following the administration of naked plasmid DNA to the kidney surface in mice2005
- Author(s)
  Ryu Hirayama, Hitoshi Sasaki, Junzo Nakamura et al.
- Journal Title
  
  Biological & Pharmaceutical Bulletin 28・1
  
  Pages: 181-184
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590133
[Journal Article] Synergistic effect of EDTA and boric acid on corneal penetration of CS-088.2005
- Author(s)
  T.Kikuchi, M.Suzuki, A.Kusai, K.Iseki, H.Sasaki
- Journal Title
  
  Int. J. Pharmaceu. 290
  
  Pages: 83-89
- Data Source
  KAKENHI-PROJECT-15590133
[Journal Article] Mechanism of permeability-enhancing effect of EDTA and bolic acid on the corneal penetration of 4-[1-hydroxy-1-methylethyl]-2-propyl-1-[4-[2-[tetrazole-5-yl]phenyl]phenyl]methylimidazole-5-carboxylic acid monohydrate (CS-088).2005
- Author(s)
  T.Kikuchi, M.Suzuki, A.Kusai, K.Iseki, H.Sasaki, K.Nakashima
- Journal Title
  
  Int. J. Pharmaceu. 290
  
  Pages: 107-114
- Data Source
  KAKENHI-PROJECT-15590133
[Journal Article] Unilateral kidney-selective gene transfer following the administration of naked plasmid DNA to the kidney surface in mice2005
- Author(s)
  Ryu Hirayama, Hitoshi Sasaki, Junzo Nakamura et al.
- Journal Title
  
  Biological & Pharmaceutical Bulletin, 28-1
  
  Pages: 181-184
- NAID
  110003665796
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590133
[Journal Article] Effect of solution composition of plasmid DNA on gene transfection following liver surface administration in mice2005
- Author(s)
  Ryu Hirayama, Hitoshi Sasaki, Junzo Nakamura et al.
- Journal Title
  
  Biological & Pharmaceutical Bulletin, 28-11
  
  Pages: 2166-2169
- NAID
  110003666420
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590133
[Journal Article] Prednisolone retention in integrated liposomes by chemical approach and pharmaceutical approach2004
- Author(s)
  Mugen Teshima, Koyo Nishida, Hitoshi Sasaki et al.
- Journal Title
  
  Journal of Controlled Release, 97-2
  
  Pages: 211-218
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590133
[Journal Article] Prednisolone retention in integrated liposomes by chemical approach and pharmaceutical approach2004
- Author(s)
  Mugen Teshima, Koyo Nishida, Hitoshi Sasaki et al.
- Journal Title
  
  Journal of Controlled Release 97・2
  
  Pages: 211-218
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590133
[Journal Article] Liver site-specific gene transfer following the administration of naked plasmid DNA to the liver surface in mice2004
- Author(s)
  Koyo Nishida, Hitoshi Sasaki, Junzo Nakamura et al.
- Journal Title
  
  Biological & Pharmaceutical Bulletin 27
  
  Pages: 1697-1699
- NAID
  110003608683
- Data Source
  KAKENHI-PROJECT-15590133
[Journal Article] In vivo gene transfection via intravitreal injection of cationic liposome/plasmid DNA complexes in rabbits2004
- Author(s)
  Shigeru Kawakami, Junzo Nakamura, Hitoshi Sasaki et al.
- Journal Title
  
  International Journal of Pharmaceutics 278
  
  Pages: 253-262
- Data Source
  KAKENHI-PROJECT-15590133
[Journal Article] Ocular pharmacokinetic/pharmacodynamic (PK/PD) modeling for bunazosin after instillation into rabbits2004
- Author(s)
  Koji Sakanaka, Junzo Nakamura, Hitoshi Sasaki et al.
- Journal Title
  
  Pharmaceutical Research 21・5
  
  Pages: 771-776
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590133
[Journal Article] Ocular pharmacokinetic/pharmacodynamic modeling for bunazosin after instillation into rabbits2004
- Author(s)
  Koji Sakanaka, Junzo Nakamura, Hitoshi Sasaki et al.
- Journal Title
  
  Pharmaceutical Research, 21-5
  
  Pages: 770-776
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590133
[Journal Article] Pharmacokinetics of phenol red in rat models of liver damage prepared by liver targeting of carbon tetrachloride2004
- Author(s)
  Takahiro Mukai, Hitoshi Sasaki, Junzo Nakamura et al.
- Journal Title
  
  Biological & Pharmaceutical Bulletin 27
  
  Pages: 595-597
- NAID
  110003608814
- Data Source
  KAKENHI-PROJECT-15590133
[Journal Article] Ocular pharmacokinetic/pharmacodynamic (PK/PD) modeling for bunazosin after instillation into rabbits2004
- Author(s)
  Koji Sasanaka, Junzo Nakamura, Hitoshi Sasaki et al.
- Journal Title
  
  Pharmaceutical Roserch 21
  
  Pages: 770-776
- Data Source
  KAKENHI-PROJECT-15590133
[Journal Article] In vivo gene transfection via intravitreal injection of cationic liposome/plasmid DNA complexes in rabbits2004
- Author(s)
  Shigeru Kawakami, Junzo Nakamura, Hitoshi Sasaki et al.
- Journal Title
  
  International Journal of Pharmaceutics, 278-2
  
  Pages: 255-262
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590133
[Journal Article] Prednisolone retention in integrated liposomes by chemical approach and pharmaceutical approach2004
- Author(s)
  Mugen Teshima, Mikiro Nakashima, Hitoshi Sasaki et al.
- Journal Title
  
  Journal of Controlled Release 97
  
  Pages: 211-218
- Data Source
  KAKENHI-PROJECT-15590133
[Journal Article] In vivo gene transfection via intravitreal injection of cationic liposome/plasmid DNA complexes in rabbits2004
- Author(s)
  Shigeru Kawakami, Junzo Nakamura, Hitoshi Sasaki et al.
- Journal Title
  
  International Journal of Pharmaceutics 278・2
  
  Pages: 255-262
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590133
[Journal Article] One-side-coated insert as a unique ophthalmic drug delivery system2003
- Author(s)
  Hitoshi Sasaki, Koyo Nishida, Mikiro Nakashima et al.
- Journal Title
  
  Journal of Controlled Release, 92-3
  
  Pages: 241-247
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590133
[Journal Article] One-side-coated insert as a unique ophthalmic drug delivery system2003
- Author(s)
  Hitoshi Sasaki, Koyo Nishida, Mikiro Nakashima et al.
- Journal Title
  
  Journal of Controlled Release 92・3
  
  Pages: 241-247
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590133
[Patent] 核酸送達用担体及び核酸送達複合体2022
- Inventor(s)
  黒崎友亮, 佐々木均
- Industrial Property Rights Holder
  長崎大学
- Industrial Property Rights Type
  特許
- Filing Date
  2022
- Overseas
- Data Source
  KAKENHI-PROJECT-20K12649
[Patent] 肺指向性薬物送達体2019
- Inventor(s)
  佐々木均、兒玉幸修、川上茂
- Industrial Property Rights Holder
  佐々木均、兒玉幸修、川上茂
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-098677
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-18H02589
[Patent] 経肺投与用薬物送達体2019
- Inventor(s)
  佐々木均、兒玉幸修、川上茂
- Industrial Property Rights Holder
  佐々木均、兒玉幸修、川上茂
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-099112
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-18H02589
[Patent] 新規ナノボールの創製2010
- Inventor(s)
  佐々木均、黒崎友亮、北原隆志、他
- Industrial Property Rights Holder
  国立大学法人長崎大学
- Industrial Property Number
  2010-043186
- Filing Date
  2010-02-26
- Data Source
  KAKENHI-PROJECT-21390010
[Patent] 薬物送達複合体2010
- Inventor(s)
  佐々木均, 黒崎友亮, 北原隆志, 藤秀人, 由井克之, 平山謙二, 森田公一
- Industrial Property Rights Holder
  長崎大学
- Industrial Property Number
  2010-043186
- Filing Date
  2010-02-26
- Data Source
  KAKENHI-PROJECT-21390010
[Presentation] 抗原提示細胞標的型ナノ粒子の経肺投与による粘膜免疫の誘導2023
- Author(s)
  黒崎友亮、兒玉幸修、中嶋幹郎、佐々木均
- Organizer
  日本薬剤学会第38年会
- Data Source
  KAKENHI-PROJECT-21H02648
[Presentation] mRNAワクチンのための負電荷微粒子の開発2022
- Author(s)
  黑﨑友亮、兒玉幸修、佐々木均
- Organizer
  日本薬剤学会第37年会
- Data Source
  KAKENHI-PROJECT-21H02648
[Presentation] RNAワクチン開発を目的としたmRNA内包三元複合体の開発2020
- Author(s)
  濵田英里、黑﨑友亮、兒玉幸修、室高広、中村忠博、佐々木均
- Organizer
  日本薬剤学会第35年会
- Data Source
  KAKENHI-PROJECT-18H02589
[Presentation] 静電的相互作用を基盤としたaptamer被膜型遺伝子ベクターの開発2019
- Author(s)
  黒崎友亮、兒玉幸修、中川博雄、中村忠博、大山要、中嶋幹郎、川上茂、佐々木均
- Organizer
  日本薬剤学会第34年会
- Data Source
  KAKENHI-PROJECT-18H02589
[Presentation] 大腸がん腹膜播種に対するMDM2-siRNA複合体の有効性評価2018
- Author(s)
  丸田由佳理, 兒玉幸修, 北原隆志, 佐々木均
- Organizer
  日本薬剤学会第33年会
- Data Source
  KAKENHI-PROJECT-18H02589
[Presentation] c-Myc-siRNA三重複合体によるメラノーマ増殖抑制に関する基礎的検討2018
- Author(s)
  三枝由香莉, 兒玉幸修, 北原隆志, 佐々木均
- Organizer
  日本薬剤学会第33年会
- Data Source
  KAKENHI-PROJECT-18H02589
[Presentation] 大腸がん腹膜播種に対するVEGF-siRNAナノ粒子の開発2018
- Author(s)
  大倉真生, 兒玉幸修, 北原隆志, 佐々木均
- Organizer
  第34回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-18H02589
[Presentation] 生体分解型siRNAベクターの構築と有用性評価2018
- Author(s)
  柿木優希, 兒玉幸修, 北原隆志, 佐々木均
- Organizer
  第34回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-18H02589
[Presentation] VEGF-siRNA複合体によるメラノーマ肺転移の抑制2018
- Author(s)
  岡田明莉, 兒玉幸修, 北原隆志, 佐々木均
- Organizer
  第34回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-18H02589
[Presentation] ポリアミノ酸で構築した生体分解型マラリアナノワクチンの開発2016
- Author(s)
  根岸智奈美、兒玉幸修、北原隆志、佐々木均
- Organizer
  日本薬剤学会第31年会
- Place of Presentation
  長良川国際会議場（岐阜県・岐阜市）
- Year and Date
  2016-05-21
- Data Source
  KAKENHI-PROJECT-26293034
[Presentation] グリコサミノグリカンで被膜した生体分解型遺伝子ベクターの開発2016
- Author(s)
  三枝由香莉、兒玉幸修、岩永真理恵、北原隆志、佐々木均
- Organizer
  日本薬剤学会第31年会
- Place of Presentation
  長良川国際会議場（岐阜県・岐阜市）
- Year and Date
  2016-05-21
- Data Source
  KAKENHI-PROJECT-26293034
[Presentation] 関節リウマチ治療を目的としたメトトレキサートを構成成分とする遺伝子ベクターの開発2016
- Author(s)
  小林瑞希、兒玉幸修、北原隆志、佐々木均
- Organizer
  日本薬剤学会第31年会
- Place of Presentation
  長良川国際会議場（岐阜県・岐阜市）
- Year and Date
  2016-05-21
- Data Source
  KAKENHI-PROJECT-26293034
[Presentation] アニオン性デンドリプレックスを用いた遺伝子デリバリーシステムの開発2015
- Author(s)
  野田稜、兒玉幸修、黑﨑友亮、中村忠博、北原隆志、佐々木均
- Organizer
  日本薬剤学会第30年会
- Place of Presentation
  長崎ブリックホール（長崎県長崎市）
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26293034
[Presentation] 抗原提示細胞標的化ナノ粒子を用いた新規がんワクチンの開発2015
- Author(s)
  花村啓紀、兒玉幸修、北原隆志、中嶋幹郎、佐々木均
- Organizer
  日本薬剤学会第30年会
- Place of Presentation
  長崎ブリックホール（長崎県長崎市）
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26293034
[Presentation] アニオン性三重複合体の眼疾患用遺伝子ベクターとしての有用性評価2015
- Author(s)
  永原忠幸、兒玉幸修、北原隆志、中嶋幹郎、佐々木均
- Organizer
  日本薬剤学会第30年会
- Place of Presentation
  長崎ブリックホール（長崎県長崎市）
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26293034
[Presentation] 生体分解型DNAナノワクチンによる悪性黒色腫の増殖抑制2015
- Author(s)
  徳永彩子、兒玉幸修、北原隆志、佐々木均
- Organizer
  第31回日本DDS学会学術集会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Year and Date
  2015-07-02
- Data Source
  KAKENHI-PROJECT-26293034
[Presentation] Dendrigraft poly-L-lysine を基材とした遺伝子ベクターの有用性評価2015
- Author(s)
  徳永彩子、兒玉幸修、樋口則英、北原隆志、佐々木均
- Organizer
  日本薬剤学会第30年会
- Place of Presentation
  長崎ブリックホール（長崎県長崎市）
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26293034
[Presentation] pH緩衝能の増大と毒性軽減を目的とした四重複合体の開発と有用性評価2015
- Author(s)
  上田由貴、兒玉幸修、三枝由香莉、北原隆志、佐々木均
- Organizer
  日本薬剤学会第30年会
- Place of Presentation
  長崎ブリックホール（長崎県長崎市）
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26293034
[Presentation] センチネルリンパ節イメージングを目指した蛍光標識γ-ポリグルタミン酸複合体の開発2014
- Author(s)
  萩森政頼, 畑辺恵里, 佐野紘平, 佐々木均, 佐治英郎, 向高弘
- Organizer
  第9回日本分子イメージング学会学術集会
- Place of Presentation
  千里ライフサイエンスセンター
- Data Source
  KAKENHI-PROJECT-24390294
[Presentation] センチネルリンパ節の蛍光イメージングを目指したγ-ポリグルタミン酸被覆ナノ粒子の作製2014
- Author(s)
  千石梓, 畑辺恵里, 萩森政頼, 佐野紘平, 佐々木均, 佐治英郎, 向高弘
- Organizer
  第14回放射性医薬品・画像診断薬研究会
- Place of Presentation
  京都勧業館, 京都
- Year and Date
  2014-09-13
- Data Source
  KAKENHI-PROJECT-24390294
[Presentation] Fetuin 被膜型複合体による新規遺伝子ベクターの構築2013
- Author(s)
  兒玉幸修、北原隆志、江頭かの子、中嶋幹郎、樋口則英、中村忠博、佐々木均
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Year and Date
  2013-03-28
- Data Source
  KAKENHI-PROJECT-23659813
[Presentation] Dendrigraft poly-L-lysine を用いた生体内分解型遺伝子ベクターの開発2013
- Author(s)
  塩川裕美、兒玉幸修、北原隆志、佐々木均
- Organizer
  日本薬剤学会第28年会
- Place of Presentation
  名古屋
- Year and Date
  2013-05-25
- Data Source
  KAKENHI-PROJECT-23659813
[Presentation] 樹状細胞標的型ナノデバイスを用いたマラリアDNA ナノワクチンの開発2013
- Author(s)
  西垣和香、兒玉幸修、北原隆志、佐々木均
- Organizer
  第30回日本薬学会九州支部大会
- Place of Presentation
  佐世保
- Year and Date
  2013-12-08
- Data Source
  KAKENHI-PROJECT-23659813
[Presentation] 生体イメージングを目指したγ-ポリグルタミン酸被覆蛍光ナノ粒子の作製2013
- Author(s)
  畑辺恵里, 萩森政頼, 佐野紘平, 佐々木均, 向高弘
- Organizer
  第63回日本薬学会近畿支部大会
- Place of Presentation
  同志社女子大学（京田辺キャンパス）
- Data Source
  KAKENHI-PROJECT-24390294
[Presentation] ポリヌクレオチド被膜型複合体による脾臓指向性新規遺伝子ベクターの開発2013
- Author(s)
  矢次結衣子、兒玉幸修、大久保智佳子、北原隆志、佐々木均
- Organizer
  日本薬剤学会第28年会
- Place of Presentation
  名古屋
- Year and Date
  2013-05-25
- Data Source
  KAKENHI-PROJECT-23659813
[Presentation] Sentinel lymph node imaging with a novel radiolabeled γ-polyglutamic acid complex2012
- Author(s)
  Sano K., Iwamiya Y., Kurosaki T., Ogawa M., Magata Y., Sasaki H., Oshima T., Maeda M., Mukai T ,
- Organizer
  The Society of Nuclear Medicine 59th Annual Meeting
- Place of Presentation
  Miami Beach (USA)
- Year and Date
  2012-06-10
- Data Source
  KAKENHI-PROJECT-24390294
[Presentation] ホスファチジルセリンアナログを用いた脾臓指向性遺伝子導入ベクターの開発2012
- Author(s)
  大久保智佳子、仲宗根ちひろ、黒崎友亮、兒玉幸修、北原隆志、佐々木均
- Organizer
  日本薬剤学会第27年会
- Place of Presentation
  神戸
- Year and Date
  2012-05-24
- Data Source
  KAKENHI-PROJECT-23659813
[Presentation] 安全かつ効果的な眼疾患用新規遺伝子ベクターの開発2012
- Author(s)
  佐々木均、兒玉幸修、黑﨑友亮、樋口則英、北原隆志、中村忠博
- Organizer
  第32回日本眼薬理学会
- Place of Presentation
  滋賀
- Year and Date
  2012-09-15
- Data Source
  KAKENHI-PROJECT-23659813
[Presentation] 肝細胞選択的なグリチルリチン含有遺伝子ベクターの開発2012
- Author(s)
  原内智慧、川鍋早紀、黒崎友亮、兒玉幸修、北原隆志、佐々木均
- Organizer
  日本薬剤学会第27年会
- Place of Presentation
  神戸
- Year and Date
  2012-05-24
- Data Source
  KAKENHI-PROJECT-23659813
[Presentation] 安全かつ効果的な眼疾患用新規遺伝子ベクターの開発2012
- Author(s)
  佐々木均、兒玉幸修、黑﨑友亮、樋口則英、北原隆志、中村忠博
- Organizer
  第32回日本眼薬理学会学術集会
- Place of Presentation
  ピアザ淡海（滋賀県大津市）
- Data Source
  KAKENHI-PROJECT-23659813
[Presentation] 静電的自己組織化を基盤としたアニオン性siRNA ベクターの開発2012
- Author(s)
  塩川裕美、兒玉幸修、原内智慧、北原隆志、佐々木均
- Organizer
  第29回日本薬学会九州支部大会
- Place of Presentation
  熊本
- Year and Date
  2012-12-08
- Data Source
  KAKENHI-PROJECT-23659813
[Presentation] 制癌剤と遺伝子同時送達を目的としたメトトレキサート被膜型遺伝子ベクターの開発2012
- Author(s)
  兒玉幸修、黒崎友亮、江頭かの子、中嶋幹郎、中川博雄、樋口則英、中村忠博、北原隆志、佐々木均
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-31
- Data Source
  KAKENHI-PROJECT-23659813
[Presentation] 静電的相互作用を利用した葉酸修飾型遺伝子ベクターの開発2011
- Author(s)
  黒崎友亮、川上茂、橋田充、佐々木均
- Organizer
  日本薬剤学会第26年会
- Place of Presentation
  東京
- Year and Date
  2011-05-29
- Data Source
  KAKENHI-PROJECT-21390010
[Presentation] グリチルリチン被膜型肝指向性遺伝子ベクターの開発2011
- Author(s)
  川鍋早紀、黒崎友亮、兒玉幸修、北原隆志、佐々木均
- Organizer
  第28回日本薬学会九州支部大会
- Place of Presentation
  福岡
- Year and Date
  2011-12-10
- Data Source
  KAKENHI-PROJECT-21390010
[Presentation] 三重複合体による新規遺伝子ベクターの開発:コンドロイチン硫酸被膜型デンドリプレックス2011
- Author(s)
  今村政信、黒崎友亮、兒玉幸修、北原隆志、佐々木均
- Organizer
  第27回日本DDS学会
- Place of Presentation
  東京
- Year and Date
  2011-06-09
- Data Source
  KAKENHI-PROJECT-21390010
[Presentation] Polyplex of pDNA with poly-L-lysine, poly-L-histidine, and γ-polyglutamic acid for biocompatible gene delivery system2011
- Author(s)
  Yukinobu Kodama, Tomoaki Kurosaki, Kanoko Egashira, Tadahiro Nakamura, Takashi Kitahara, Hitoshi Sasaki
- Organizer
  日本薬物動態学会第26回年会
- Place of Presentation
  広島
- Year and Date
  2011-11-17
- Data Source
  KAKENHI-PROJECT-23659813
[Presentation] 三重構造を有した生体分解型遺伝子ベクターの構築2011
- Author(s)
  黒崎友亮、川上茂、橋田充、佐々木均
- Organizer
  第27回日本DDS学会
- Place of Presentation
  東京
- Year and Date
  2011-06-09
- Data Source
  KAKENHI-PROJECT-21390010
[Presentation] Ternary complexes of pDNA with cationic polymer and anionic polymer for secure gene delivery systems2010
- Author(s)
  T.Kurosaki, T.Kitahara, T.Nakamura, H.Sasaki
- Organizer
  FIP Pharmaceutical Sciences 2010 world congress
- Place of Presentation
  New Orleans
- Year and Date
  2010-11-18
- Data Source
  KAKENHI-PROJECT-21390010
[Presentation] 注射薬の後発医薬品に関する品質及び安全性の評価2010
- Author(s)
  中嶋幹郎、荒木良介、中嶋弥穂子、中村純三、佐々木均、八坂貴宏
- Organizer
  第4回日本ジェネリック医薬品学会学術大会
- Place of Presentation
  さいたま
- Data Source
  KAKENHI-PROJECT-20590147
[Presentation] 自己組織化により形成される葉酸修飾型遺伝子ベクターの開発2010
- Author(s)
  森下圭美、黒崎友亮、北原隆志、中村忠博、籐秀人、佐々木均
- Organizer
  第27回日本薬学会九州支部大会
- Place of Presentation
  長崎
- Year and Date
  2010-12-11
- Data Source
  KAKENHI-PROJECT-21390010
[Presentation] Dendrimerを用いた三次元型遺伝子ベクターの開発2010
- Author(s)
  山下祐未、黒崎友亮、森下圭美、兒玉幸修、北原隆志、佐々木均
- Organizer
  第27回日本薬学会九州支部大会
- Place of Presentation
  長崎
- Year and Date
  2010-12-11
- Data Source
  KAKENHI-PROJECT-21390010
[Presentation] γ-Polyglutamic acid被膜型遺伝子ベクターの開発2010
- Author(s)
  黒崎友亮、北原隆志、兒玉幸修、藤秀人、濱本知之、佐々木均
- Organizer
  第26回日本DDS学会
- Place of Presentation
  大阪
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-21390010
[Presentation] 脾臓標的化遺伝子ベクターの開発とDNAワクチンベクターへの応用2010
- Author(s)
  黒崎友亮、北原隆志、兒玉幸修、西田孝洋、麓伸太郎、佐々木均
- Organizer
  日本薬剤学会第25年会
- Place of Presentation
  徳島
- Year and Date
  2010-05-13
- Data Source
  KAKENHI-PROJECT-21390010
[Presentation] Dendrimerを用いた三元型遺伝子ベクターの開発2010
- Author(s)
  山下祐未、黒崎友亮、森下圭美、兒玉幸修、北原隆志、佐々木均
- Organizer
  第27回日本薬学会九州支部大会
- Place of Presentation
  長崎
- Year and Date
  2010-12-11
- Data Source
  KAKENHI-PROJECT-21390010
[Presentation] Pulmonary gene delivery of hybrid vector, lipopolyplex containing N-lauroylsarcosine, via systemic route.2010
- Author(s)
  H.Sasaki, T.Kurosaki, H.To, T.Kitahara
- Organizer
  FIP Pharmaceutical Sciences 2010 world congress
- Place of Presentation
  New Orleans
- Year and Date
  2010-11-18
- Data Source
  KAKENHI-PROJECT-21390010
[Presentation] COMPLEX OF PLASMID DNA WITH N-LAUROYLSARCOSINE LIPOSOMES THROUGH CALCIUM BRIDGIHG FOR EFFECTIVE AND SECURE GENE DELIVERY2009
- Author(s)
  Masato Nakai, Tomoaki Kurosaki, Yukinobu Kodama, Takashi Kitahara, Hitoshi Sasaki
- Organizer
  Asian Federation for Pharmaceutical Sciences 2009
- Place of Presentation
  福岡
- Year and Date
  2009-10-17
- Data Source
  KAKENHI-PROJECT-21390010
[Presentation] 肺指向性を持つ全身投与型遺伝子ベクターの開発と解析2009
- Author(s)
  黒崎友亮、高山幸三、北原隆志、麓伸太郎、西田孝洋、濱本知之、佐々木均
- Organizer
  第25回日本DDS学会
- Place of Presentation
  東京
- Year and Date
  2009-07-03
- Data Source
  KAKENHI-PROJECT-21390010
[Presentation] 負電荷高分子を用いた被膜型遺伝子導入ベクターの開発2009
- Author(s)
  黒崎友亮、北原隆志、麓伸太郎、西田孝洋、中村純三、藤秀人、佐々木均
- Organizer
  日本薬剤学会第24年会
- Place of Presentation
  静岡
- Year and Date
  2009-05-21
- Data Source
  KAKENHI-PROJECT-21390010
[Presentation] PULMONARY GENE DELIVERY OF HYBRID VECTOR, LIPOPOLYPLEX CONTAINING N-LAUROYLSARCOSINE, VIASYSTEMIC ROUTE.2009
- Author(s)
  Tomoaki Kurosaki, Kozo Takayama, Takashi Kitahara, Tomoyuki Hamamoto, Hitoshi Sasaki
- Organizer
  Asian Federation for Pharmaceutical Sciences 2009
- Place of Presentation
  福岡
- Year and Date
  2009-10-16
- Data Source
  KAKENHI-PROJECT-21390010
[Presentation] 静電的相互作用を基盤とした多糖被膜型遺伝子ベクターの開発と解析2009
- Author(s)
  黒崎友亮、濱本知之、北原隆志、藤秀人、佐々木均
- Organizer
  遺伝子デリバリー研究会第9回シンポジウム
- Place of Presentation
  大阪
- Year and Date
  2009-07-09
- Data Source
  KAKENHI-PROJECT-21390010
[Presentation] 新規遺伝子ベクターの開発 : カルシウムイオンを介したプラスミドDNA-アニオン性リポソーム複合体2009
- Author(s)
  中井將人、黒崎友亮、児玉幸修、藤秀人、浜本知之、北原隆志、佐々木均
- Organizer
  第24回長崎DDS研究会
- Place of Presentation
  長崎
- Year and Date
  2009-12-18
- Data Source
  KAKENHI-PROJECT-21390010
[Presentation] 新規遺伝子ベクターの開発 : カルシウムイオンを介したプラスミドDNA-アニオン性リポソーム複合体2009
- Author(s)
  中井將人、黒崎友亮、児玉幸修、藤秀人、浜本知之、北原隆志、佐々木均
- Organizer
  第26回日本薬学会九州支部大会
- Place of Presentation
  福岡
- Year and Date
  2009-12-12
- Data Source
  KAKENHI-PROJECT-21390010
[Presentation] INFLUENCE OF DISEASE STAGE ON POLYPLEX AND LIPOPLEX MEDIATED GENE DELIVERY IN MURINE HEPATITIS2009
- Author(s)
  Hitoshi Sasaki, Tomoaki Kurosaki, Hideto To, Tomoyuki Hamamoto, Takashi Kitahara
- Organizer
  Asian Federation for Pharmaceutical Sciences 2009
- Place of Presentation
  福岡
- Year and Date
  2009-10-17
- Data Source
  KAKENHI-PROJECT-21390010
[Presentation] γ-Polyglutamic acid被膜型遺伝子ベクターの開発とメカニズムの解明2009
- Author(s)
  佐々木均、黒崎友亮、濱本知之、麓伸太郎、西田孝洋、北原隆志
- Organizer
  日本薬剤学会第24年会
- Place of Presentation
  静岡
- Year and Date
  2009-05-23
- Data Source
  KAKENHI-PROJECT-21390010
[Presentation] Influence of murine hepatitis induced by D-(+)-galactosamine hydrochloride and lipopolysaccharide on gene explession of polyethyleneimine/pDNA polyplex2008
- Author(s)
  Sasaki, H., Kurosaki, T., To, H., Kitahara, T.
- Organizer
  2008 AAPS Annual Meeting and Exposition
- Place of Presentation
  Atlanta, USA
- Data Source
  KAKENHI-PROJECT-18590143
[Presentation] Effect of disease stage on gene expression by polyplex and lipoplex in murine hepatitis induced by carbon tetrachloride2008
- Author(s)
  Teshima, M., Yoshida, S., Fumoto, S., Nishida, K., Nakamura, J., Nakashima, M., Hamamoto, T., To, H., Kitahara, T., Sasaki, H.
- Organizer
  23rd JSSX Annual Meeting
- Place of Presentation
  Kumamoto, Japan
- Data Source
  KAKENHI-PROJECT-18590143
[Presentation] Influence of murine hepatitis induced by D-(+)-galactos amine hydrochloride and lipopolysaccharide on gene explession of polyethyleneimine/pDNA polyplex2008
- Author(s)
  Sasaki, H, et al.
- Organizer
  2008 AAPS Annual Meeting and Exposition.
- Place of Presentation
  Atlanta, USA
- Year and Date
  2008-11-19
- Data Source
  KAKENHI-PROJECT-18590143
[Presentation] Topics of Individualised Medicine2007
- Author(s)
  H.Sasaki
- Organizer
  World Congress of Pharmacy and Pharmaceutical Sciences 2007
- Place of Presentation
  Beijing,China
- Year and Date
  2007-09-06
- Data Source
  KAKENHI-PROJECT-18590143
[Presentation] Ichikawa N : Delivery timing of plasmid DNA with non-viral carrier in murine hepatitis2006
- Author(s)
  Sasaki H, Yoshida S, Kitahara T, To H
- Organizer
  21st FAPA congress
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-18590143
[Presentation] 肝再生の遺伝子デリバリーに対する影響-肝切除マウスにおけるpolyethylenimine/pDNA複合体の遺伝子発現2006
- Author(s)
  山内浩子, 夛田勇巳, 一川暢宏, 籐秀人, 佐々木均, 中嶋幹郎, 西田孝洋, 中村純三
- Organizer
  日本薬学会第126年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-18590143
[Presentation] Partial hepatectomy enhances polyethylenimine-mediated plasmid DNA delivery2006
- Author(s)
  Sasaki H
- Organizer
  The 66th World Congress of Pharmacy and Pharmaceutical Sciences(FIP 2006)
- Place of Presentation
  Salvador Bahia, Brazil
- Data Source
  KAKENHI-PROJECT-18590143
[Presentation] Polyethylenimineを用いた遺伝子デリバリーへの病態の影響-四塩化炭素誘発肝障害マウスにおける検討2006
- Author(s)
  佐々木均, 山内浩子, 夛田勇巳, 一川暢宏, 籐秀人, 中嶋幹郎, 西田孝洋, 中村純三
- Organizer
  日本薬学会第126年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-18590143
[Presentation] Secure and effective gene vector of polyamidoamine dendrimer pharmaceutically modified with anionic polymer
- Author(s)
  Yukinobu Kodama, Yumi Yamashita, Takashi Kitahara, Hitoshi Sasaki
- Organizer
  5th Pharmaceutical Sciences World Congress
- Place of Presentation
  メルボルン（オーストラリア）
- Year and Date
  2014-04-13 – 2014-04-16
- Data Source
  KAKENHI-PROJECT-26293034
[Presentation] Effects of antiarrhythmic agents on beating rhythm of cultured cardiomyocyte networks on an agarose microchamber chip
- Author(s)
  Ohwaki Y、Araki R、Tominaga R、Terazono H、To H、Sasaki H、Nakashima M
- Organizer
  The Second Asian Symposium on Pharmaceutical Sciences
- Place of Presentation
  Nagasaki,、Japan
- Data Source
  KAKENHI-PROJECT-20590147
[Presentation] Dendrigraft poly-L-lysineを構成成分とした生分解型siRNAベクターの構築
- Author(s)
  藏本悠、兒玉幸修、北原隆志、佐々木均
- Organizer
  日本薬剤学会第29年会
- Place of Presentation
  大宮ソニックシティビル（大宮）
- Year and Date
  2014-05-20 – 2014-05-22
- Data Source
  KAKENHI-PROJECT-26293034
[Presentation] Secure and effective gene vector of polyamidoamine dendrimer pharmaceutically modified with anionic polymer
- Author(s)
  Yukinobu Kodama, Yumi Yamashita, Takashi Kitahara, Sasaki Hitoshi
- Organizer
  5th Pharmaceutical Sciences World Congress
- Place of Presentation
  Melbourne Convention and Exhibition Centre（メルボルン）
- Year and Date
  2014-04-13 – 2014-04-16
- Data Source
  KAKENHI-PROJECT-24590198
[Presentation] 医療用医薬品を用いたGMP基準の新規遺伝子ベクターの開発
- Author(s)
  西垣和香、兒玉幸修、北原隆志、佐々木均
- Organizer
  日本薬剤学会第29年会
- Place of Presentation
  大宮ソニックシティビル（大宮）
- Year and Date
  2014-05-20 – 2014-05-22
- Data Source
  KAKENHI-PROJECT-26293034
[Presentation] センチネルリンパ節イメージングを目指した蛍光標識γ-ポリグルタミン酸複合体の開発
- Author(s)
  萩森政頼, 畑辺恵里, 佐野紘平, 佐々木均, 佐治英郎, 向高弘
- Organizer
  第9回日本分子イメージング学会学術集会
- Place of Presentation
  千里ライフサイエンスセンター, 豊中
- Year and Date
  2014-05-22 – 2014-05-23
- Data Source
  KAKENHI-PROJECT-24390294
[Presentation] Nanoparticles electrostatically coated with folic acid for effective and safe gene delivery
- Author(s)
  Hitoshi Sasaki, Yukinobu Kodama, Tamami Morishita, Takashi Kitahara
- Organizer
  5th Pharmaceutical Sciences World Congress
- Place of Presentation
  Melbourne Convention and Exhibition Centre（メルボルン）
- Year and Date
  2014-04-13 – 2014-04-16
- Data Source
  KAKENHI-PROJECT-24590198
[Presentation] Dendrigraft poly-L-lysineを構成成分とした生分解型siRNAベクターの構築
- Author(s)
  藏本悠、兒玉幸修、北原隆志、佐々木均
- Organizer
  日本薬剤学会第29年会
- Place of Presentation
  大宮ソニックシティビル（大宮）
- Year and Date
  2014-05-20 – 2014-05-22
- Data Source
  KAKENHI-PROJECT-24590198
[Presentation] Nanoparticles electrostatically coated with folic acid for effective and safe gene delivery
- Author(s)
  Hitoshi Sasaki, Yukinobu Kodama, Tamami Morishita, Takashi Kitahara
- Organizer
  5th Pharmaceutical Sciences World Congress
- Place of Presentation
  メルボルン（オーストラリア）
- Year and Date
  2014-04-13 – 2014-04-16
- Data Source
  KAKENHI-PROJECT-26293034
[Presentation] Development of fluorescent γ-polyglutamic acid complex for sentinel lymph node imaging
- Author(s)
  Hagimori M., Hatabe E., Sano K., Sasaki H., Saji H., Mukai T.
- Organizer
  2014 World Molecular Imaging Congress
- Place of Presentation
  COEX Convention Center, Seoul
- Year and Date
  2014-09-17 – 2014-09-20
- Data Source
  KAKENHI-PROJECT-24390294
[Presentation] 医療用医薬品を用いたGMP基準の新規遺伝子ベクターの開発
- Author(s)
  西垣和香、兒玉幸修、北原隆志、佐々木均
- Organizer
  日本薬剤学会第29年会
- Place of Presentation
  大宮ソニックシティビル（大宮）
- Year and Date
  2014-05-20 – 2014-05-22
- Data Source
  KAKENHI-PROJECT-24590198

1. NAKASHIMA Mikiro (00260737)

# of Collaborated Projects: 4 results

# of Collaborated Products: 11 results
2. KUROSAKI Tomoaki (00582016)

# of Collaborated Projects: 4 results

# of Collaborated Products: 54 results
3. NAKAMURA Junzo (30115901)

# of Collaborated Projects: 3 results

# of Collaborated Products: 16 results
4. TO Hideto (90346809)

# of Collaborated Projects: 2 results

# of Collaborated Products: 36 results
5. KAWAKAMI Shigeru (20322307)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
6. KITAHARA Takashi (30380934)

# of Collaborated Projects: 2 results

# of Collaborated Products: 42 results
7. KODAMA Yukinobu (50448510)

# of Collaborated Projects: 2 results

# of Collaborated Products: 25 results
8. MUKAI Takahiro (30284706)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
9. NISHIDA Koyo (20237704)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
10. 平山謙二 (60189868)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. NAKASHIMA Mihoko (00301367)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
12. TANAKA Masafumi (40411904)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KAWAKAMI Atsushi (90325639)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. SAKAEDA Toshiyuki (00304098)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. Asahina Izumi (30221039)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 太田伸生 (10143611)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
17. 濱野真二郎 (70294915)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 新留琢郎 (26204210)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 岩本直樹 (80437897)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 一瀬邦弘 (60437895)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 古賀智裕 (90537284)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 右田清志 (60264214)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 中村英樹 (10437832)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 中村忠博 (60882199)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
25. 山下親正 (30622188)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 室高広 (10832834)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
27. 小守壽文 (00252677)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 住田吉慶 (50456654)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 鎌倉慎治 (80224640)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 三浦桂一郎 (10634446)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. SHIMADA Takashi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. NAGATSUKA Shin-Ichiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. TACHIKI Hidehisa

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. KUMAGAI Takashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 原昌士

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. 後藤典子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SASAKI Hitoshi 佐々木 均

佐々木 均 ササキ ヒトシ

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Development of nucleic acid vaccine for mucosal-application based on pharmaceutics and immunology -For Covid-19 prevention-Principal Investigator

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Development of new nucleic acid medicines for intractable respiratory diseasesPrincipal Investigator

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Development of the novel technique intended to the prophylaxis and treatment of neglected tropical diseasesPrincipal Investigator

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Development of novel gene therapy targeting age-related macular degenerationPrincipal Investigator

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The development of self-assembly nano-devices based on electrostatic interaction and the application to selective drug deliveryPrincipal Investigator

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Influence of disease stage and pharmacotherapy on gene deliveryPrincipal Investigator

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Development of topical gene delivery system for clinical applicationPrincipal Investigator

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SASAKI Hitoshi 佐々木均

佐々木均ササキヒトシ