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Yamaguchi Kazuhiko  山口 和彦

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YAMAGUCHI Kazuhiko  山口 和彦

山口 和彦  ヤマグチ カズヒコ

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Researcher Number 00191221
Other IDs
Affiliation (Current) 2025: 国立研究開発法人国立精神・神経医療研究センター, 神経研究所 微細構造研究部, 客員研究員
Affiliation (based on the past Project Information) *help 2019: 国立研究開発法人国立精神・神経医療研究センター, 神経研究所 微細構造研究部, 客員研究員
2018: 国立研究開発法人理化学研究所, 脳神経科学研究センター, 研究員
2017: 国立研究開発法人理化学研究所, 脳科学総合研究センター, 研究員
2013: 独立行政法人理化学研究所, 脳科学総合研究センター, 研究員
2010 – 2012: The Institute of Physical and Chemical Research, 運動学習制御研究チーム, 副チームリーダー … More
2008 – 2009: The Institute of Physical and Chemical Research, 記憶学習機構研究チーム, 副チームリーダー
2001: 理化学研究所, 記憶学習機構研究チーム, 副チームリーダー(研究職)
1993 – 1998: 杏林大学, 医学部, 助教授
1990 – 1992: 岡崎国立共同研究機構, 生理学研究所, 助手 Less
Review Section/Research Field
Principal Investigator
神経・脳内生理学 / Basic / Social brain science / Neurophysiology and muscle physiology / Neurophysiology and muscle physiology / Neurophysiology and muscle physiology
Except Principal Investigator
Neuroscience in general / Cell biology / Biological Sciences
Keywords
Principal Investigator
パッチクランプ法 / 海馬 / シンタキシン / 小脳 / 長期抑圧 / グルタミン酸受容体 / シナプス可塑性 / プルキンエ細胞 / オ-タプス / HPC-1 … More / Caチャネル / 培養神経細胞 / 運動学習 / アンパ型グルタミン酸受容体 / スパイン / 受容体トラフィッキング / 後根神経節 / シナプス / シナプス伝達 / アンチセンスオリゴヌクレオチド / 出芽 / 脊髄後根神経節細胞 / 脊髄後根神経節 / 神経突起末端部 / Kチャネル / アラキドン酸 / 最初期遺伝子 / 樹状突起スパイン / 抑制性介在ニューロン / 反動性増強 / 誤差信号 / 受容体リサイクリング / マウス / リサイクリング / 長期抑圧LTD / Readily releasable pool / Synaptic vesicle / Vesicle docking / Syntaxin / Exocytosis / Autapse / Synapse / Hippocampus / cyclic AMP / 歯状回顆粒細胞 / 海馬神経細胞 / Aキナーゼ / EPSC / フォルスコリン / シナプス開口放出 / 歯状回 / A-キナーゼ / 即時放出可能プール / cAMP / オータプス / 開口放出 / L-type Ca-channel / nifedipine / intracellular perfusion / filopodia / whole cell clamp / contrast enhancing camera / axoplasmic flow / neurite-outgrowth / 無血清培養 / 高コントラストカメラ / カルシウムチャネル / オメガコノトキシン / ニィフェディピン / 細胞質流動運動 / フィロポディア / 成長円錐 / 神経突起伸長 / ケージ化ペプチド / LTD / トラフィッキング / AMPA受容体 / 学習 / 数理モデル / エンドサイトーシス / エキソサイトーシス / セムリキ森林ウイルス / レンチウイルス / ウイルスベクター / GFP / 樹状突起 / トランスロケーション / 網膜 / 一酸化窒素 / epsc / シナプトファイシン / ホールセル・クランプ法 / 単離培養系 / アンチセンスDNA / 活性ゾーン / シナプスファイシン / Naナイトロプルッシド / 興奮性シナプス電流 / ホールセル・パッチクランプ法 / 共培養 / GABA / グルタミン酸 / Naチャネル / 神経突起末端 / ホールセルクランプ法 / パッちクランプ法 / 逆行性伝達物質 … More
Except Principal Investigator
HPC-1 / REGULATED SECRETION / NEURITE SPROUTING / EXOCYTOSIS / SYNTAXIN 1A / 長期増強 / 最初期遺伝子 / カイニン酸 / 海馬 / 神経可塑性 / 制御性分泌 / 神経発芽 / 開口放出 / physiology / micropipet / catenin / adhesion molecule / cadherin / cell adhesion / 細胞間接着力 / カテニン / 張力 / 接着力 / 接着分子 / マイクロピペット / カドヘリン / 細胞接着 / リソホスファチジン酸 / ホスファチジン酸 / リゾホスファチジン酸 / ホスファチジル酸 / リン脂質 / シナプス小胞 / シナプス伝達 Less
  • Research Projects

    (15 results)
  • Research Products

    (74 results)
  • Co-Researchers

    (14 People)
  •  Elucidation of motor learning strategy via two types of the cerebellar synaptic plasticityPrincipal Investigator

    • Principal Investigator
      Yamaguchi Kazuhiko
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Basic / Social brain science
    • Research Institution
      National Center of Neurology and Psychiatry
      Institute of Physical and Chemical Research
  •  Elucidation of molecular mechanism of synaptic plasticity by kinetic analysis of receptor traffickingPrincipal Investigator

    • Principal Investigator
      YAMAGUCHI Kazuhiko
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurophysiology and muscle physiology
    • Research Institution
      The Institute of Physical and Chemical Research
  •  Elucidation of regulatory mechanism of AMPA-receptor's trafficking by visualization of its intracellular pool.Principal Investigator

    • Principal Investigator
      YAMAGUCHI Kazuhiko
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurophysiology and muscle physiology
    • Research Institution
      The Institute of Physical and Chemical Research
  •  新規リソホスファチジル酸アシル基転移酵素エンドフィリンのシナプス伝達における役割

    • Principal Investigator
      根本 康夫
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
      The Institute of Physical and Chemical Research
  •  Elucidation of molecular mechanism of synaptic exocytosis and its modification mechanism in mammalian hippocampal autapse.Principal Investigator

    • Principal Investigator
      YAMAGUCHI Kazuhiko
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      神経・脳内生理学
    • Research Institution
      Kyorin University
  •  培養神経細胞を用いたシナプス抑圧退行物質の検索と作用機構の解明Principal Investigator

    • Principal Investigator
      山口 和彦
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyorin University
  •  培養神経細胞を用いたシナプス抑圧退行物質検索の為の検定系の開発Principal Investigator

    • Principal Investigator
      山口 和彦
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyorin University
  •  STUDY OF A NEURON-SPECIFIC PROTEIN,HPC-1, WHICH REGULATES NEURONAL SPROUTING.

    • Principal Investigator
      AKAGAWA Kimio
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neuroscience in general
    • Research Institution
      KYORIN UNIVERSITY
  •  神経突起末端部における神経細胞膜蛋白質HPC-1の機能に関する生理学的研究Principal Investigator

    • Principal Investigator
      山口 和彦
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      神経・脳内生理学
    • Research Institution
      Kyorin University
  •  培養した痛覚系1次求心神経細胞の神経突起末端部膜の生理学的、薬理学的性質Principal Investigator

    • Principal Investigator
      山口 和彦
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyorin University
  •  活性ゾーソの有無に注目した逆行性伝達物質検定のための神経培養系の開発Principal Investigator

    • Principal Investigator
      山口 和彦
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyorin University
  •  シナプス前膜蛋白質に対するアンチセンスDNA等を用いた神経伝達物質放出機構の解析Principal Investigator

    • Principal Investigator
      山口 和彦
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      神経・脳内生理学
    • Research Institution
      Kyorin University
  •  Direct Measurement of Cell-Cell Adhesion

    • Principal Investigator
      YONEMURA Sigenobu
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Cell biology
    • Research Institution
      National Institute for Physiological Sciences
  •  人為的に形成させた培養中枢神経細胞間シナプスを用いた逆行性情報伝達物質の検定Principal Investigator

    • Principal Investigator
      山口 和彦
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Okazaki National Research Institutes
  •  Investigation of the molecular mechanism of the neurite-outgrowth using a contrast enhanced camera and intracellular perfusion methods.Principal Investigator

    • Principal Investigator
      YAMAGUCHI Kazuhiko
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Neurophysiology and muscle physiology
    • Research Institution
      Okazaki National Research Institutes National institute for Physiological Sciences Grant-in-Aid for Scientific Research (C)

All 2020 2019 2018 2017 2014 2013 2012 2011 2010 2009 2008 Other

All Journal Article Presentation Book

  • [Book] 分子・細胞・シナプス2008

    • Author(s)
      山口和彦
    • Publisher
      東京大学出版会
    • Data Source
      KAKENHI-PROJECT-20500363
  • [Journal Article] Assessment of Long-term Depression Induction in Adult Cerebellar Slices2019

    • Author(s)
      Yamaguchi Kazuhiko, Ito Masao
    • Journal Title

      Journal of Visualized Experiments

      Volume: - Issue: 152

    • DOI

      10.3791/59859

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K01982
  • [Journal Article] Autism-like behaviours and enhanced memory formation and synaptic plasticity in Lrfn2/SALM1-deficient mice2017

    • Author(s)
      Morimura Naoko、Yasuda Hiroki、Yamaguchi Kazuhiko、Katayama Kei-ichi、Hatayama Minoru、Tomioka Naoko H.、Odagawa Maya、Kamiya Akiko、Iwayama Yoshimi、Maekawa Motoko、Nakamura Kazuhiko、Matsuzaki Hideo、Tsujii Masatsugu、Yamada Kazuyuki、Yoshikawa Takeo、Aruga Jun
    • Journal Title

      Nature Communications

      Volume: 8 Issue: 1 Pages: 15800-15800

    • DOI

      10.1038/ncomms15800

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K06789, KAKENHI-PROJECT-17K01982, KAKENHI-PROJECT-16K18878, KAKENHI-PROJECT-15H04889, KAKENHI-PROJECT-16H04666, KAKENHI-PROJECT-16H05373, KAKENHI-PROJECT-26430003, KAKENHI-PROJECT-26590161, KAKENHI-PROJECT-15K09814
  • [Journal Article] Long-term depression as a model of cerebellar plasticity2014

    • Author(s)
      Ito M, yamaguchi K, Nagao S, Yamazaki, T.
    • Journal Title

      Progress in Brain research

      Volume: 210 Pages: 1-30

    • DOI

      10.1016/b978-0-444-63356-9.00001-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500472
  • [Journal Article] Long-term depression as a model of cerebellar plasticity2014

    • Author(s)
      Ito M, Yamaguchi K, Nagao S, Yamazaki T
    • Journal Title

      Progress in Brain Research

      Volume: (in press)

    • Data Source
      KAKENHI-PROJECT-23500472
  • [Journal Article] Remodeling of monoplanar Purkinje cell dendrites during cerebellar circuit formation2011

    • Author(s)
      Kaneko, M., Yamaguchi, K., Eiraku, M., Sato, M., Takata, N., Kiyohara, Y., Mishina, M., Hirase, H., Hashikawa, T. and Kengaku, M
    • Journal Title

      PLoS ONE

      Volume: 6 Issue: 5 Pages: e20108-e20108

    • DOI

      10.1371/journal.pone.0020108

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249012, KAKENHI-PLANNED-22123008, KAKENHI-PROJECT-23500472, KAKENHI-PROJECT-23700399
  • [Journal Article] CRMP5 (Collapsin Response Mediator Protein 5) regulates dendritic development and synaptic plasticity in the cerebellar2011

    • Author(s)
      Yamashita N, Mosinger B, Roy A, Miyazaki M, Ugajin K, Nakamura F, Sasaki Y, Yamaguchi K, Kolattukudy P, Goshima Y
    • Journal Title

      Purkinje cell.J.Neurosci. 31

      Pages: 1773-1779

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20500363
  • [Journal Article] CRMP5(collapsin response mediator protein 5) regulates dendritic development and synaptic plasticity in the cerebellar Purkinje cells2011

    • Author(s)
      Yamashita N, Mosinger B, Roy A, Miyazaki M, Ugajin K, Nakamura F, Sasaki Y, Yamaguchi K, Kolattukudy P, Goshima Y.
    • Journal Title

      Journal of Neuroscience

      Volume: 31(5) Issue: 5 Pages: 1773-79

    • DOI

      10.1523/jneurosci.5337-10.2011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21700411, KAKENHI-PROJECT-22500336, KAKENHI-PROJECT-23500472
  • [Journal Article] RNG105 deficiency impairs the dendritic localization of mRNAs for Na^+/K^+ ATPase subunit isoforms and leads to the degeneration of neuronal networks.2010

    • Author(s)
      Shiina N, Yamaguchi K, Tokunaga M
    • Journal Title

      J.Neurosci 30

      Pages: 12816-12830

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20500363
  • [Journal Article] Dual involvement of G-substrate in motor learning revealed by gene deletion.2009

    • Author(s)
      Endo S., Shuto F., Le D.T., Okamoto T., Ikeda T., Suzuki M., Kawahara S., Yanagihara D., Sato Y., Yamada K., Sakamoto T., Kirino Y., Hartell N.A., Yamaguchi K., Itohara S., Naim A., Greengarg P., Nagao S., Ito M.
    • Journal Title

      Proc.Natl.Acad.Sci.USA 106

      Pages: 3525-3530

    • NAID

      120006399303

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20500363
  • [Journal Article] Connexin43 and Bergmann glial gap junctions in cerebellar function.2008

    • Author(s)
      Tanaka M, Yamaguchi K, Tatsukawa T, Theis M, Willecke K, Itohara S
    • Journal Title

      Front Neurosci. 2(2)

      Pages: 225-233

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20500363
  • [Journal Article] Lack of connexin43-mediated Bergmann glial gap junctional coupling does not affect cerebellar long-term depression, motor coordination or eyeblink conditioning.2008

    • Author(s)
      Tanaka M., Yamaguchi K., Tatsukawa T., Nishioka C., Nishiyama H., Theis M., Willecke K., Itohara S.
    • Journal Title

      Front.Behav.Neurosci. 2

      Pages: 1-14

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20500363
  • [Presentation] 小脳機能の基礎研究:現状と展望2020

    • Author(s)
      山口 和彦
    • Organizer
      小脳研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K01982
  • [Presentation] 小脳の長期抑圧LTDは運動学習に必須か?2019

    • Author(s)
      山口 和彦
    • Organizer
      Motor control 研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K01982
  • [Presentation] Analysis of Rapid Decrease in EPSC Amplitude after Sudden Block of Exocytic Insertion of AMPAR into Parallel Fiber-Purkinje Cell synapse2018

    • Author(s)
      Yamaguchi, Kazuhiko
    • Organizer
      第41回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-17K01982
  • [Presentation] Mechanism of long-term synaptic plasticity in rat cerebellar Purkinje cell2018

    • Author(s)
      Yamaguchi, Kazuhiko
    • Organizer
      第75回藤原セミナー」”中枢神経系のハブとしての小脳”
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K01982
  • [Presentation] Reduction of exocytic insertion of AMPA-receptors into parallel fiber-Purkinje cell synapse is involved in LTD-expression2018

    • Author(s)
      Yamaguchi, Kazuhiko
    • Organizer
      11th FENS forum of neuroscience
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K01982
  • [Presentation] Patch-clamp techniques for studying physiological properties of the central neuron2017

    • Author(s)
      Yamaguchi K.
    • Organizer
      IBRO-APRC Advanced Hong Kong School of Neuroscience
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K01982
  • [Presentation] Kinetic analysis of constitutive and activity dependent receptor-trafficking in cerebellar Purkinje cell2017

    • Author(s)
      Yamaguchi K.
    • Organizer
      Society for Neuroscience, Washington D.C., U.S.A.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K01982
  • [Presentation] Nitric oxide dependent change in AMPA receptor trafficking in Purkinje cell analysed using a kinetic model of receptor trafficking2014

    • Author(s)
      Yamaguchi K
    • Organizer
      the 37th Congress of the International Union of Physiological Sciences (IUPS 2013)
    • Place of Presentation
      Birmingham UK
    • Year and Date
      2014-03-17
    • Data Source
      KAKENHI-PROJECT-23500472
  • [Presentation] 小脳プルキンエ細胞長期抑圧で内在化した AMPA 受容体の細胞内分布2014

    • Author(s)
      山口和彦
    • Organizer
      第91回日本生理学会大会
    • Place of Presentation
      鹿児島
    • Year and Date
      2014-03-17
    • Data Source
      KAKENHI-PROJECT-23500472
  • [Presentation] 小脳平行線維-プルキンエ細胞間シナプスにおける AMPA 受容体トラフィッキングに対する側方拡散の寄与2013

    • Author(s)
      山口和彦, 永雄総一
    • Organizer
      第90回日本生理学会大会
    • Place of Presentation
      東京
    • Year and Date
      2013-03-28
    • Data Source
      KAKENHI-PROJECT-23500472
  • [Presentation] 受容体側方拡散の小脳プルキンエ細胞シナプスにおけるAMPA受容体トラフィッキングへの寄与2013

    • Author(s)
      山口 和彦
    • Organizer
      生理学研究所 研究会 「シナプス・神経ネットワークの機能ダイナミクス」
    • Place of Presentation
      岡崎      愛知
    • Invited
    • Data Source
      KAKENHI-PROJECT-23500472
  • [Presentation] Suppression of AMPA-receptor endocytosis is the mechanism underlying LTP at the parallel fiber-Purkinje cell synapse.2012

    • Author(s)
      Yamaguchi K, Nagao S.
    • Organizer
      International Synapse Research Workshop 2012 Understanding of synapse pathology, from genome mutation to functional defects.
    • Place of Presentation
      Okazaki, Japan
    • Data Source
      KAKENHI-PROJECT-23500472
  • [Presentation] ケージ化阻害ペプチドを用いた受容体トラフィッキングのキネティック解析により解明された小脳 LTD における AMPA 受容体エキソサイトーシスの抑制2012

    • Author(s)
      山口和彦, 永雄総一
    • Organizer
      第89回日本生理学会大会
    • Place of Presentation
      松本
    • Year and Date
      2012-03-31
    • Data Source
      KAKENHI-PROJECT-23500472
  • [Presentation] ケージ化阻害ペプチドを用いた受容体トラフィッキングのキネティック解析により解明された小脳LTDにおけるAMPA受容体エキソサイトーシスの抑制2012

    • Author(s)
      Yamaguchi K, Nagao S.
    • Organizer
      第89回日本生理学会大会シンポジウム
    • Place of Presentation
      松本
    • Data Source
      KAKENHI-PROJECT-23500472
  • [Presentation] 小脳平行線維プルキンエ細胞間シナプス長期増強におけるAMPA 受容体トラフィッキングのキネティック解析2012

    • Author(s)
      山口和彦, 永雄総一
    • Organizer
      第35回日本神経科学大会
    • Place of Presentation
      名古屋
    • Year and Date
      2012-09-21
    • Data Source
      KAKENHI-PROJECT-23500472
  • [Presentation] Change in trafficking kinetics of AMPA-receptor underlying LTD revealed by photolysis of caged inhibitory peptide in cerebellar Purkinje cell2012

    • Author(s)
      Yamaguchi, K. Nagao, S
    • Organizer
      8th Federation of European Neuroscience Forum of Neuroscience
    • Place of Presentation
      Barcelona Spain
    • Year and Date
      2012-07-16
    • Data Source
      KAKENHI-PROJECT-23500472
  • [Presentation] Lrfn2/SALM1 regulates excitatory synapse function in the hippocampus and its deficient mice display mental disorder-like behavioral abnormalities2011

    • Author(s)
      Morimura N, Yasuda H, Yamada K, Tomioka N, Katayama K, Yamaguchi K, Ota M, Kamiya A, Aruga J
    • Organizer
      Symposium : Emerging synapse organizers in hippocampal neural circuits 34th Ann. Meeting of Jpn Neurosci. Soc
    • Place of Presentation
      Yokohama
    • Year and Date
      2011-09-15
    • Data Source
      KAKENHI-PROJECT-23500472
  • [Presentation] Multi-site modulation of AMPA-receptor trafficking during cerebellar LTD2011

    • Author(s)
      Yamaguchi K and Nagao S
    • Organizer
      4th International Symposium of the Society for Research on the Cerebellum
    • Place of Presentation
      Tokyo
    • Year and Date
      2011-09-18
    • Data Source
      KAKENHI-PROJECT-23500472
  • [Presentation] Multi-site modulation of AMPA-receptor trafficking during cerebellar LTD.2011

    • Author(s)
      Yamaguchi K and Nagao S.
    • Organizer
      4th International Symposium of the Society for Research on the Cerebellum
    • Place of Presentation
      Tokyo Japan
    • Data Source
      KAKENHI-PROJECT-23500472
  • [Presentation] Activity-dependent Change in AMPA-Receptor Trafficking Investigated by Photolysis of a Caged Inhibitory Peptide in Cerebellar Purkinje Cell.2011

    • Author(s)
      Yamaguchi.K, Tatsu Y, Nagao S. Ito M.
    • Organizer
      8th IBRO World Congress of Neurosci.
    • Place of Presentation
      Florence Italy
    • Data Source
      KAKENHI-PROJECT-23500472
  • [Presentation] An analysis based on a data-driven kinetic model of receptor-trafficking in cerebellar Purkinje cell predicts insufficiency of receptor-destabilization as a mechanism of LTD.2011

    • Author(s)
      Yamaguchi, K., Nagao, S.
    • Organizer
      The 11th Japan-Korea-China Joint Workshop on Neurobiology and Neuroinformatics
    • Place of Presentation
      Okinawa Japan
    • Data Source
      KAKENHI-PROJECT-23500472
  • [Presentation] AMPA型受容体エクソサイトーシスの活動依存性抑圧の平行線維-プルキンエ細胞間シナプスにおける長期抑圧発現への関与.2011

    • Author(s)
      山口和彦、達 吉郎、永雄総一
    • Organizer
      第34回日本神経科学大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23500472
  • [Presentation] AMP 型受容体エクソサイトーシスの活動依存性抑圧の平行線維-プルキンエ細胞間シナプスにおける長期抑圧発現への関与2011

    • Author(s)
      山口和彦, 達 吉郎, 永雄総一
    • Organizer
      第34回日本神経科学大会
    • Place of Presentation
      横浜
    • Year and Date
      2011-09-15
    • Data Source
      KAKENHI-PROJECT-23500472
  • [Presentation] Activity-dependent Change in AMPA- receptor trafficking investigated by photolysis of a caged inhibitory peptide in cerebellar Purkinje cell2011

    • Author(s)
      Yamaguchi.K, Tatsu Y, Nagao S. Ito M
    • Organizer
      8th IBRO World Congress of Neurosci
    • Place of Presentation
      Florence Italy
    • Year and Date
      2011-07-16
    • Data Source
      KAKENHI-PROJECT-23500472
  • [Presentation] 小脳プルキンエ細胞における構成性および活動依存性 AMPA 受容体トラフィッキングのデータ駆動性キネティックモデル2011

    • Author(s)
      山口和彦, 達 吉郎, 永雄総一
    • Organizer
      第88回日本生理学会大会
    • Place of Presentation
      横浜
    • Year and Date
      2011-03-28
    • Data Source
      KAKENHI-PROJECT-23500472
  • [Presentation] An analysis based on a data-driven kinetic model of receptor-trafficking in cerebellar Purkinje cell predicts insufficiency of receptor-destabilization as a mechanism of LTD2011

    • Author(s)
      Yamaguchi, K., Nagao, S
    • Organizer
      The 11th Japan-Korea- China Joint Workshop on Neurobiology and Neuroinformatics
    • Place of Presentation
      Okinawa
    • Year and Date
      2011-12-18
    • Data Source
      KAKENHI-PROJECT-23500472
  • [Presentation] 小脳プルキンエ細胞GluR2細胞内プールの樹状突起スパインからシャフトへの活動依存性移動の蛍光蛋白質2重発現法による解析2010

    • Author(s)
      山口和彦、清水知佳、中澤敬信、伊藤正男
    • Organizer
      第87回日本生理学会大会
    • Place of Presentation
      盛岡
    • Year and Date
      2010-05-19
    • Data Source
      KAKENHI-PROJECT-20500363
  • [Presentation] ケージドペプチドを用いた小脳平行線維プルキンエ細胞間シナプスにおけるAMPA受容体トラフィッキングの速度定数の計測2010

    • Author(s)
      山口和彦、達吉郎、永雄総一、伊藤正男
    • Organizer
      第33回日本神経科学大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-09-02
    • Data Source
      KAKENHI-PROJECT-20500363
  • [Presentation] Effects of LTD-Inducing Stimulation on Endocytic Rate-Constant of AMPA-Receptor Trafficking at Parallel Fiber-Purkinje Cell Synapse in Cerebellum2010

    • Author(s)
      Yamaguchi K., et al.
    • Organizer
      生理学研究所研究会"記憶学習行動の基盤としてのシナプス可塑性"
    • Place of Presentation
      生理学研究所 岡崎
    • Year and Date
      2010-12-02
    • Data Source
      KAKENHI-PROJECT-20500363
  • [Presentation] 小脳プルキンエ細胞におけるGluR2細胞内プールの活動依存性トランスロケーションとシナプス可塑性:蛍光蛋白質2重発現法による解析2010

    • Author(s)
      山口和彦
    • Organizer
      生理学研究所研究会"シナプス伝達の概念志向型研究"
    • Place of Presentation
      岡崎
    • Year and Date
      2010-12-08
    • Data Source
      KAKENHI-PROJECT-20500363
  • [Presentation] AMPA-receptor trafficking in cerebellar Purkinje cell : A kinetic analysis using a whole-cell recording technique.2010

    • Author(s)
      Yamaguchi K.
    • Organizer
      IBRO School of Neuroscience in Hong Kong
    • Place of Presentation
      Chinese University of Hong Kong, Hong Kong
    • Year and Date
      2010-06-02
    • Data Source
      KAKENHI-PROJECT-20500363
  • [Presentation] AMPA-receptor trafficking in cerebellar Purkinje cell : A kinetic analysis. Symposium "Neural circuit : Develop and Plasticity"2010

    • Author(s)
      山口和彦
    • Organizer
      5^<th> Congress of FAONS and XXVIII Annual Meeting of IAN.
    • Place of Presentation
      Lucknow India
    • Year and Date
      2010-11-27
    • Data Source
      KAKENHI-PROJECT-20500363
  • [Presentation] Perinatal perturbation of NMDA receptor in the vestibular nucleus attenuates cerebellar function.2010

    • Author(s)
      Lai SK, Shum DKY, Yung WH, Yamaguchi K, Chan YS
    • Organizer
      The 40th annual meeting of the Society for Neuroscience
    • Place of Presentation
      San Diego USA
    • Year and Date
      2010-11-17
    • Data Source
      KAKENHI-PROJECT-20500363
  • [Presentation] Attenuation of cerebellar plasticity after neonatal perturbation of NMDA receptors in the vestibular nucleus2010

    • Author(s)
      Lai SK, Yamaguchi K, Yung WH, Chan YS
    • Organizer
      Poster 5^<th> Congress of FAONS and XXVIII Annual Meeting of IAN.
    • Place of Presentation
      Lucknow India
    • Year and Date
      2010-11-26
    • Data Source
      KAKENHI-PROJECT-20500363
  • [Presentation] Effects of LTD-Inducing Stimulation on Endocytic Rate-Constant of AMPA-Receptor Trafficking at Parallel Fiber-Purkinje Cell Synapse in Cerebellum2010

    • Author(s)
      Yamaguchi K, Nagao S
    • Organizer
      生理学研究所研究会"記憶学習行動の基盤としてのシナプス可塑性"
    • Place of Presentation
      岡崎
    • Year and Date
      2010-11-26
    • Data Source
      KAKENHI-PROJECT-20500363
  • [Presentation] AMPA-receptor trafficking in cerebellar Purkinje cell : A kinetic analysis using a whole-cell recording technique.2010

    • Author(s)
      山口和彦
    • Organizer
      IBRO School of Neuroscience Chinese University of Hong Kong
    • Place of Presentation
      Hong Kong
    • Year and Date
      2010-06-02
    • Data Source
      KAKENHI-PROJECT-20500363
  • [Presentation] 小脳プルキンエ細胞におけるGluR2細胞内プールの活動依存性トランスロケーションとシナプス可塑性:蛍光蛋白質2重発現法による解析2010

    • Author(s)
      山口和彦, 他
    • Organizer
      生理学研究所研究会"シナプス伝達の概念志向型研究"
    • Place of Presentation
      生理学研究所 岡崎
    • Year and Date
      2010-12-08
    • Data Source
      KAKENHI-PROJECT-20500363
  • [Presentation] Involvement of actin-myosin interaction in cerebellar long-term depression2010

    • Author(s)
      Tatsukawa T, Nagao S, Yamaguchi K
    • Organizer
      The 40th annual meeting of the Society for Neuroscience
    • Place of Presentation
      San Diego USA
    • Year and Date
      2010-11-14
    • Data Source
      KAKENHI-PROJECT-20500363
  • [Presentation] AMPA-receptor trafficking in cerebellar Purkinje cell : A kinetic analysis.2010

    • Author(s)
      Yamaguchi K.
    • Organizer
      Symposium "Neural circuit : Develop and Plasticity" 5^<th> Congress of Federation of Asia-Oceania Neuroscience (FAONS)
    • Place of Presentation
      Hotel Clarks Avadh, Lucknow, India
    • Year and Date
      2010-11-27
    • Data Source
      KAKENHI-PROJECT-20500363
  • [Presentation] An integrative kinetic model of AMPA-receptors constitutive trafficking and LTD/LTP in cerebellar2009

    • Author(s)
      山口和彦
    • Organizer
      Purkinje cell 36^<th> International Congress of Physiological Sciences
    • Place of Presentation
      京都
    • Year and Date
      2009-07-28
    • Data Source
      KAKENHI-PROJECT-20500363
  • [Presentation] AMPA受容体トラフィッキングのキネティックスとシナプス可塑性2009

    • Author(s)
      山口和彦
    • Organizer
      神経組織の成長・再生・移植研究会第24回学術集会
    • Place of Presentation
      (ホテル天坊)群馬県伊香保
    • Year and Date
      2009-06-21
    • Data Source
      KAKENHI-PROJECT-20500363
  • [Presentation] AMPA受容体トラフィッキングのキネティックスとシナプス可塑性2009

    • Author(s)
      山口和彦
    • Organizer
      神経組織の成長・再生・移植研究会題24回学術集会
    • Place of Presentation
      伊香保
    • Year and Date
      2009-06-21
    • Data Source
      KAKENHI-PROJECT-20500363
  • [Presentation] Translocation of GluR2 pool in the dendritic spine of cerebellar Purkinje cells under long-term depression.2009

    • Author(s)
      Yamaguchi K, Shimizu C, Sato Y, Furuichi T, Ito M
    • Organizer
      The 39^<th> annual meeting of the Society for Neuroscience
    • Place of Presentation
      Chicago USA
    • Year and Date
      2009-10-19
    • Data Source
      KAKENHI-PROJECT-20500363
  • [Presentation] An integrative kinetic model of AMPA-receptors constitutive trafficking and LTD/LTP in cerebellar Purkinje cell2009

    • Author(s)
      山口和彦
    • Organizer
      36^<th> International Congress of Physiological Sciences
    • Place of Presentation
      (国立京都国際会館)京都
    • Year and Date
      2009-07-28
    • Data Source
      KAKENHI-PROJECT-20500363
  • [Presentation] プルキンエ細胞樹状突起スパインにおけるGluR2細胞内プールの活動依存性移動へのPKCの関与2009

    • Author(s)
      山口和彦
    • Organizer
      第32回日本神経科学大会
    • Place of Presentation
      名古屋
    • Year and Date
      2009-09-16
    • Data Source
      KAKENHI-PROJECT-20500363
  • [Presentation] Translocation of GluR2 pool in the dendritic spine of cerebellar Purkinje cells under long-term depression2009

    • Author(s)
      Yamaguchi K, Shimizu C, Sato Y, Furuichi T, Ito M.
    • Organizer
      39^<th> annual meeting of Society for Neuroscience
    • Place of Presentation
      Chicago IL USA
    • Year and Date
      2009-10-19
    • Data Source
      KAKENHI-PROJECT-20500363
  • [Presentation] プルキンエ細胞樹状突起スパインにおけるGluR2細胞内プールの活動依存性移動へのPKCの関与2009

    • Author(s)
      山口和彦
    • Organizer
      第32回日本神経科学大会
    • Place of Presentation
      (名古屋国際会議場)名古屋
    • Year and Date
      2009-09-16
    • Data Source
      KAKENHI-PROJECT-20500363
  • [Presentation] Roles of actin in constitutive and activity-dependent trafficking of AMPA-receptors in the cerebellar Purkinje cell.2008

    • Author(s)
      山口和彦
    • Organizer
      US-Japan Brain Research Collaborative Program. Workshop on Receptor Trafficking and Cell Biology of Neurons : Physiology and Disease.
    • Place of Presentation
      Pacific Grove USA
    • Year and Date
      2008-02-26
    • Data Source
      KAKENHI-PROJECT-20500363
  • [Presentation] LRR膜貫通分子Lrfn2/SALM1は海馬興奮性シナプスの形態や機能調節および可塑性に関与する2008

    • Author(s)
      守村直子、山口和彦、安田浩樹、片山圭一、原直子、太田摩耶、神谷明子、有賀純
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会 合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-10
    • Data Source
      KAKENHI-PROJECT-20500363
  • [Presentation] 小脳プルキンエ細胞樹状突起スパインにおけるAMPA受容体分布変化と長期抑圧2008

    • Author(s)
      山口和彦
    • Organizer
      第31回日本神経科学大会
    • Place of Presentation
      東京国際フォーラム
    • Year and Date
      2008-07-10
    • Data Source
      KAKENHI-PROJECT-20500363
  • [Presentation] 小脳プルキンエ細胞樹状突起におけるグルタミン酸受容体の活動依存性分布変化2008

    • Author(s)
      山口和彦、清水知佳、佐藤友美、古市貞一、伊藤正男
    • Organizer
      第85回日本生理学会大会
    • Place of Presentation
      東京
    • Year and Date
      2008-03-26
    • Data Source
      KAKENHI-PROJECT-20500363
  • [Presentation] プルキンエ細胞におけるAMPA受容体双方向性トラフィッキングとモデルによる考察2008

    • Author(s)
      山口和彦
    • Organizer
      生理学研究所研究会"新たなコンセプトでシナプス伝達を考える"
    • Place of Presentation
      岡崎
    • Year and Date
      2008-09-18
    • Data Source
      KAKENHI-PROJECT-20500363
  • [Presentation] 小脳プルキンエ細胞におけるAMPA受容体トラフィッキングの速度論的解析とLTP/LTDのメカニズム2008

    • Author(s)
      山口和彦
    • Organizer
      生理学研究所研究会 シナプス研究会"シナプス成熟と可塑性のダイナミクス"
    • Place of Presentation
      岡崎
    • Year and Date
      2008-12-04
    • Data Source
      KAKENHI-PROJECT-20500363
  • [Presentation] RNG105 deficiency impairs the denderitic transport on Na+/K+-ATPase subunit isoform mRNA and the formation of synapses and neuronal networks.2008

    • Author(s)
      Shiina N, Yamaguchi K, Tokunaga M
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会 合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-11
    • Data Source
      KAKENHI-PROJECT-20500363
  • [Presentation] 小脳プルキンエ細胞樹状突起スパインにおけるアンパ受容体分布変化と長期抑圧2008

    • Author(s)
      山口和彦、清水知佳、佐藤友美、古市貞一、伊藤正男
    • Organizer
      第31回日本神経科学大会
    • Place of Presentation
      東京
    • Year and Date
      2008-07-10
    • Data Source
      KAKENHI-PROJECT-20500363
  • [Presentation] アラキドン酸はアストロサイトの接触によって誘発されるシナプス形成のカギをにぎる2008

    • Author(s)
      濱裕、安藤亮子、山口和彦、宮脇敦史
    • Organizer
      第31回日本神経科学大会
    • Place of Presentation
      東京
    • Year and Date
      2008-07-11
    • Data Source
      KAKENHI-PROJECT-20500363
  • [Presentation] Changes in kinetic parameters of receptor trafficking underlying synaptic plasticity in cerebellum

    • Author(s)
      Yamaguchi K.
    • Organizer
      Molecular and Cellular Cognition Society (MCCS-Asia 6th Annual Meeting in Kyoto
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23500472
  • [Presentation] Suppression of AMPA-receptor-exocytosis during cerebellar LTD revealed by kinetic analysis of receptor trafficking using caged inhibitory peptide

    • Author(s)
      Yamaguchi K, Nagao S.
    • Organizer
      Symposium "Chemical neurobiology" 89th Annual Meeting of Jpn Physiol. Soc.
    • Place of Presentation
      Matsumoto, Japan
    • Data Source
      KAKENHI-PROJECT-23500472
  • [Presentation] Kinetic analysis of AMPA type glutamate receptors trafficking upon LTP at the parallel fiber-Purkinje cell synapse in cerebellum

    • Author(s)
      Yamaguchi K, Nagao S.
    • Organizer
      35th Anual Meeting of Jpn Society for Neuroscience
    • Place of Presentation
      Nagoya, Japan
    • Data Source
      KAKENHI-PROJECT-23500472
  • [Presentation] 小脳プルキンエ細胞長期抑圧で内在化したAMPA受容体の細胞内分布

    • Author(s)
      山口 和彦
    • Organizer
      第91回日本生理学会大会
    • Place of Presentation
      鹿児島
    • Data Source
      KAKENHI-PROJECT-23500472
  • [Presentation] Nitric oxide dependent change in AMPA receptor trafficking in Purkinje cell analysed using a kinetic model of receptor trafficking

    • Author(s)
      Yamaguchi K.
    • Organizer
      the 37th Congress of the International Union of Physiological Sciences (IUPS 2013)
    • Place of Presentation
      Birmingham UK
    • Data Source
      KAKENHI-PROJECT-23500472
  • [Presentation] Change in trafficking kinetics of AMPA-receptor underlying LTD revealed by photolysis of caged inhibitory peptide in cerebellar Purkinje cell

    • Author(s)
      Yamaguchi, K. Nagao, S.
    • Organizer
      8th Federation of European Neuroscience Forum of Neuroscience
    • Place of Presentation
      Barcelona, Spain
    • Data Source
      KAKENHI-PROJECT-23500472
  • 1.  AKAGAWA Kimio (80129303)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 2.  YONEMURA Sigenobu (60192811)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  NAGAFUCHI Akira (80218023)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  TSUKITA Sachiko (00188517)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  OSANAI Makoto (90286419)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  FUJIWARA Tomonori (90255399)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  FUJINO Ichiro (30265764)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  根本 康夫 (30250088)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  Aruga Jun
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  Yasuda Hiroki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  Yoshikawa Takeo
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  YAMASHITA Naoya
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 13.  三品 昌美
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 14.  守村 直子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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