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Nakazawa Kenichi  中澤 憲一

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NAKAZAWA Kenichi  中澤 憲一

中澤 憲一  ナカザワ ケンイチ

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Researcher Number 00198061
Other IDs
Affiliation (Current) 2025: 国立医薬品食品衛生研究所, 薬理部, 主任研究官
Affiliation (based on the past Project Information) *help 2005: National Institute of Health Sciences, Division of Pharmacology, Section Chief Researcher, 薬理部・第二室, 室長
2004: 国立医薬品食品衛生研究所, 薬理部第二室, 室長
2003: 国立医薬品食品衛生研究所, 薬理部第2室, 室長
2002: National Institute of Health Sciences Division of Pharmacology Section Leader Research Officer, 薬理部・第二室室長
2001 – 2002: 国立医薬品食品衛生研究所, 薬理部, 室長 … More
1998 – 1999: 国立医薬品食品衛生研究所, 薬理部, 室長
1997: 国立医薬品食品衛生研究所, 薬理部, 主任研究官
1994: 国立衛生試験所, 薬理部, 研究員 Less
Review Section/Research Field
Principal Investigator
Biological pharmacy / Biological pharmacy / Physical pharmacy
Keywords
Principal Investigator
ATP / イオン・チャネル / P2X受容体 / molecular biology / purinoceptor / ion channel / 分子生物学 / プリン受容体 / アフリカツメガエル卵母細胞 / function … More / structure / atomic force microscopy / P2X receptor / 構造改変 / ATP受容体 / タンパク質 / 機能 / 構造 / 原子間力顕微鏡 / Xenopus oocyte / structure-function relationship / mutagenesis / GFP visularization / 膜電流解析 / 共焦点顕微鏡 / 発現系 / GFP / GFP分子可視化法 / 構造-機能相関 / 変異導入 / GFP可視化 / membrane current / 膜電流 / イオン-チャネル / 膜電位固定法 / 相補的DNA(cDNA) / アデノシン5′-ミリン酸(ATP) / ニコチン様アセチルコリン受容体 Less
  • Research Projects

    (4 results)
  • Research Products

    (27 results)
  •  Molecular Pharmacology of ATP Receptor using Atomic Force MicroscopyPrincipal Investigator

    • Principal Investigator
      NAKAZAWA Kenichi
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      National Institute of Health Sciences
  •  Studies on receptor structure-function relationship using molecular biological techniques and GFP molecular visualizationPrincipal Investigator

    • Principal Investigator
      NAKAZAWA Kenichi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      National Institute of Health Sciences
  •  Studies on Structure-Function Relationship of ATP Receptor/channel using Molecular Biological TechniquesPrincipal Investigator

    • Principal Investigator
      NAKAZAWA Kenichi
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      National Institute of Health Sciences
  •  分子生物学的手法を用いてのニコチン受容体チャネルに対する細胞外ATPの作用の検討Principal Investigator

    • Principal Investigator
      中澤 憲一
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Physical pharmacy
    • Research Institution
      国立衛生試験所

All 2005 2004 2003

All Journal Article

  • [Journal Article] Purification and aqueous phase atomic force microscopic observation of recombinant P2X2 receptor.2005

    • Author(s)
      Nakazawa, K., Yamakoshi, Y.,.Tsuchiya, T., Ohno, Y.
    • Journal Title

      Eur.J.Pharmacol. 518

      Pages: 107-110

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590089
  • [Journal Article] Purification and aqueous phase atomic force microscopic observation of recombinant P2X2 receptor.2005

    • Author(s)
      Nakazawa, K., Yamakoshi, Y., Tsuchiya, T., Ohno, Y.
    • Journal Title

      European Journal of Pharmacology 518

      Pages: 107-110

    • Data Source
      KAKENHI-PROJECT-15590089
  • [Journal Article] Purification and aqueous phase atomic force microscopic observation of recombinant P2X2 receptor2005

    • Author(s)
      Nakazawa, K., Yamakoshi, Y., Tsuchiya, T., Ohno, Y.
    • Journal Title

      Eur. J. Pharmacol. 518

      Pages: 107-110

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590089
  • [Journal Article] Characterization of Voltage-dependent Gating of P2X2 Receptor/channel.2005

    • Author(s)
      Nakazawa, K., Ohno, Y.
    • Journal Title

      European Journal of Pharmacology 508

      Pages: 23-30

    • Data Source
      KAKENHI-PROJECT-15590089
  • [Journal Article] Characterization of Voltage-dependent Gating of P2X2 Receptor/channel2005

    • Author(s)
      Nakazawa, K., Ohno, Y.
    • Journal Title

      Eur.J.Pharmacol. 508

      Pages: 23-30

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590089
  • [Journal Article] Characterization of Voltage-dependent Gating of P2X2 Receptor/channel2005

    • Author(s)
      Nakazawa, K., Ohno, Y.
    • Journal Title

      Eur. J. Pharmacol. 508

      Pages: 23-30

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590089
  • [Journal Article] Modulation of voltage-gated Ca2+ current by 4-hydroxynonenal in dentate granule cells2004

    • Author(s)
      Akaishi, T., Nakazawa, K., Sato, K., Saito, H., Ohno, Y., Ito, Y.
    • Journal Title

      Biol. Pharm. Bull. 27

      Pages: 174-179

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590089
  • [Journal Article] 4-Hydroxynonenal modulates the long-term potentiation induced by L-type Ca2+ channel activation in the rat dentate gyrus in vitro.2004

    • Author(s)
      Akaishi, T., Nakazawa, K., Sato, K., Ohno, Y., Ito, Y.
    • Journal Title

      Neurosci. Lett. 370

      Pages: 155-159

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590089
  • [Journal Article] Desensitization of P2X2 receptor/channel pore mutants2004

    • Author(s)
      Nakazawa, K., Ohno, Y.
    • Journal Title

      Eur.J.Pharmacol. 495

      Pages: 27-33

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590089
  • [Journal Article] Amino acid substitutions from an indispensable disulfide bond affect P2X2 receptor activation2004

    • Author(s)
      Nakazawa, K., Ojima, H., Ishii-Nozawa, R., Takeuchi, K., Ohno, Y.
    • Journal Title

      Eur. J. Pharmacol. 483

      Pages: 29-35

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590089
  • [Journal Article] Amino acid substitutions from an Indispensable bisulfide bond affect P2X2 receptor activation.2004

    • Author(s)
      Nakazawa, K., Ojima, H., Ishii-Nozawa, R., Takeuchi, K., Ohno, Y.
    • Journal Title

      Eur.J.Pharmacol. 483

      Pages: 29-35

    • Data Source
      KAKENHI-PROJECT-15590089
  • [Journal Article] 4-Hydroxynonenal modulates the long-term potentiation induced by L-type Ca2+ channel activation in the rat dentate gyrus in vitro2004

    • Author(s)
      Akaishi, T., Nakazawa, K., Sato, K., Ohno, Y., Ito, Y.
    • Journal Title

      Neurosci.Lett. 370

      Pages: 155-159

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590089
  • [Journal Article] 4-Hydroxynonenal modulates the long-term potentiation induced by L-type Ca2+ channel activation in the rat dentate gyrus in vitro.2004

    • Author(s)
      Akaishi, T., Nakazawa, K., Sato, K., Ohno, Y., Ito, Y.
    • Journal Title

      Neurosci.Lett. 370

      Pages: 155-159

    • Data Source
      KAKENHI-PROJECT-15590089
  • [Journal Article] Hydrogen peroxide modulates whole cell Ca2+ currents through L-type channels in cultured rat dentate granule cells2004

    • Author(s)
      Akaishi, T., Nakazawa, K., Sato, K., Saito, H., Ohno, Y., Ito, Y.
    • Journal Title

      Neurosci.Lett. 356

      Pages: 25-28

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590089
  • [Journal Article] Modulation of voltage-gated Ca2+ current by 4-hydroxynonenal in dentate granule cells2004

    • Author(s)
      Akaishi, T., Nakazawa, K., Sato, K., Saito, H., Ohno, Y., Ito, Y.
    • Journal Title

      Biol.Pharm.Bull. 27

      Pages: 174-179

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590089
  • [Journal Article] Amino acid substitutions from an indispensable disulfide bond affect P2X2 receptor activation2004

    • Author(s)
      Nakazawa, K., Ojima, H., Ishii-Nozawa, R., Takeuchi, K., Ohno, Y.
    • Journal Title

      Eur.J.Pharmacol. 483

      Pages: 29-35

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590089
  • [Journal Article] Hydrogen peroxide modulates whole cell Ca2+ currents through L-type channels in cultured rat dentate granule cells.2004

    • Author(s)
      Akaishi, T., Nakazawa, K., Sato, K., Saito, H., Ohno, V., Ito, Y.
    • Journal Title

      Neurosci.Lett. 356

      Pages: 25-28

    • Data Source
      KAKENHI-PROJECT-15590089
  • [Journal Article] Hydrogen peroxide modulates whole cell Ca2+ currents through L-type channels in cultured rat dentate granule cells2004

    • Author(s)
      Akaishi, T., Nakazawa, K., Sato, K., Saito, H., Ohno, Y., Ito, Y.
    • Journal Title

      Neurosci. Lett. 356

      Pages: 25-28

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590089
  • [Journal Article] Desensitization of P2X2 receptor/channel pore mutants2004

    • Author(s)
      Nakazawa, K, Ohno, Y.
    • Journal Title

      Eur. J. Pharmacol. 495

      Pages: 27-33

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590089
  • [Journal Article] Modulation of voltage-gated Ca2+ current by 4-hydroxynonenal in dentate granule cells.2004

    • Author(s)
      Akaishi, T., Nakazawa, K., Sato, K., Saito, H., Ohno, Y., Ito, Y.
    • Journal Title

      Biol.Pharm.Bull. 27

      Pages: 174-179

    • Data Source
      KAKENHI-PROJECT-15590089
  • [Journal Article] Desensitization of P2X2 receptor/channel pore mutants.2004

    • Author(s)
      Nakazawa, K., Ohno, Y.
    • Journal Title

      Eur.J.Pharmacol. 495

      Pages: 27-33

    • Data Source
      KAKENHI-PROJECT-15590089
  • [Journal Article] Block by phytoestrogens of recombinant human neuronal nicotinic receptors2003

    • Author(s)
      Nakazawa, K., Ohno, Y.
    • Journal Title

      J. Pharmacol. Sci. 93

      Pages: 118-121

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590089
  • [Journal Article] Block by phytoestrogens of recombinant human neuronal nicotinic receptors2003

    • Author(s)
      Nakazawa, K., Ohno, Y.
    • Journal Title

      J.Pharmacol.Sci. 93

      Pages: 118-121

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590089
  • [Journal Article] Estrogens inhibit L-glutamate uptake activity of astrocytes via membrane estrogen receptor alpha2003

    • Author(s)
      Sato, K., Matsuki, N., Ohno, Y., Nakazawa, K.
    • Journal Title

      J.Neurochem. 86

      Pages: 1498-1505

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590089
  • [Journal Article] Intracellular disulfide bond that affects ATP responsiveness of P2X2 receptor/channel2003

    • Author(s)
      Nakazawa, K., Ojima, H., Ishii-Nozawa, R., Takeuchi, K., Ohno, Y.
    • Journal Title

      Eur.J.Pharmacol. 474

      Pages: 205-208

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590089
  • [Journal Article] Estrogens inhibit L-glutamate uptake activity of astrocytes via membrane estrogen receptor alpha2003

    • Author(s)
      Sato, K., Matsuki, N., Ohno, Y., Nakazawa, K.
    • Journal Title

      J. Neurochem. 86

      Pages: 1498-1505

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590089
  • [Journal Article] Intracellular disulfide bond that affects ATP responsiveness of P2X2 receptor/channel2003

    • Author(s)
      Nakazawa, K., Ojima, H., Ishii-Nozawa, R., Takeuchi, K., Ohno, Y.
    • Journal Title

      Eur. J. Pharmacol. 474

      Pages: 205-208

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590089

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