HAKAMATA YOJI 袴田陽二

… Alternative Names

袴田陽二ハカマタヨウジ

HAKAMATA Yoji 袴田陽二

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Researcher Number	00218380
Other IDs
Affiliation (Current)	2025: 日本獣医生命科学大学, 獣医学部, 教授
Affiliation (based on the past Project Information) *help	2024: 日本獣医生命科学大学, 獣医学部, 教授 2020 – 2022: 日本獣医生命科学大学, 獣医学部, 教授 2012 – 2014: 日本獣医生命科学大学, 獣医学部, 教授 2000 – 2005: Jichi Medical School, Faculty of Medicine, Lecturer, 医学部, 講師
Review Section/Research Field	Principal Investigator Laboratory animal science Except Principal Investigator Basic Section 55060:Emergency medicine-related / Basic Section 55010:General surgery and pediatric surgery-related / Gastroenterology / Circulatory organs internal medicine / Digestive surgery / General surgery
Keywords	Principal Investigator 国際情報交換 / in vivoイメージングシステム / トランスジェニック / スナネズミ / 幹細胞 / 神経細胞死 / 脳虚血 / トランスジェニック動物 / 間葉系幹細胞 / 再生医療 / 神経再生 … More Except Principal Investigator … More KRP-203 / FTY720 / Viral hepatitis / ウイルス性肝炎 / 遺伝子銃 / 脳障害 / 心停止蘇生 / 水素吸入 / フェロトーシス / 吸収機能 / 細胞競合 / 潰瘍性大腸炎関連腫瘍 / 臓器再生 / 再生機構 / 小腸疾患 / 体性幹細胞 / オルガノイド / 炎症性腸疾患 / 潰瘍性大腸炎 / 上皮置換 / 組織修復 / 細胞移植 / 幹細胞 / 小腸移植 / 短腸症候群 / Lymphocyte homing / Chronic hepatitis / リンパ球ホーミング / ウイスル性肝炎 / 慢性肝炎 / Cardiomyocyte / Inflammation / Oxidative stress / Ischemic heart disease / Atherosclerosis / Cytokine / 心筋細胞 / 炎症反応 / 酸化ストレス / 虚血性心疾患 / 動脈硬化 / サイトカイン / Gene gun / Hydrodynamic DNA injection / KF506 / Non-specific immunosuppressant / DNA vaccine / Liver transplantation / ラット / B型肝炎 / 非特異的免没抑制剤 / ハイドロダイナミクス法 / FK506 / 非特異的免疫抑制剤 / DNAワクチン / 肝移植 / solid tumor therapy / local therapy / Gene Gun / gene therapy / 固形癌治療 / 局所治療 / 遺伝子治療 Less

水素によるフェロトーシス抑制機構の解明と水素吸入療法の最適化
- Principal Investigator
  
  多村知剛
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Keio University
Functional analysis of small intestinal epithelial organoid-based transplant graft
- Principal Investigator
  
  SUGIMOTO Shinya
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Keio University
Establishment of bio-imaging system for detecting neural stem cellPrincipal Investigator
- Principal Investigator
  
  HAKAMATA YOJI
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  Nippon Veterinary and Life Science University
Development of the lymphocyte-homing modulator against hepatitis
- Principal Investigator
  
  KOBAYASHI Eiji, 金子隆志
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  JICHI MEDICAL SCHOOL
心血管疾患におけるMIFの発現とその役割
- Principal Investigator
  
  TAKAHASHI Masafumi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Shinshu University Graduate School of Medicine
  Jichi Medical University
Development for DNA vaccination against viral hepatitis recurrence after the liver transplantation using gene gun
- Principal Investigator
  
  KOBAYASHI Eiji
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Jichi Medical University
Cancer Gene Therapy with a Hand-Held Gene Gun
- Principal Investigator
  
  KOBAYASHI Eiji
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Jichi Medical School

All 2021 2020 2015 2014 2013 2012 2006 2005

All Journal Article Presentation

[Journal Article] An organoid-based organ-repurposing approach to treat short bowel syndrome2021
- Author(s)
  Sugimoto S, Kobayashi E, Fujii M, Ohta Y, Arai K, Matano M, Ishikawa K, Miyamoto K, Toshimitsu K, Takahashi S, Nanki K, Hakamata Y, Kanai T, Sato T.
- Journal Title
  
  Nature
  
  Volume: 592 Pages: 99-104
- DOI
  10.1038/s41586-021-03247-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06176, KAKENHI-PROJECT-20H03746, KAKENHI-PROJECT-20H03757, KAKENHI-PROJECT-18KK0246, KAKENHI-PROJECT-23K20316
[Journal Article] Mannitol infusion immediately after reperfusion suppresses the development of focal cortical infarction after temporary cerebral ischemia in gerbils.2014
- Author(s)
  Ito U, Hakamata Y, Watabe K, Oyanagi K.
- Journal Title
  
  Neuropathology
  
  Volume: 34 Issue: 4 Pages: 360-369
- DOI
  10.1111/neup.12113
- NAID
  120007100195
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24500428, KAKENHI-PROJECT-24500498, KAKENHI-PROJECT-25640028
[Journal Article] Astrocytic involvement in the maturation phenomenon after temporary cerebral ischemia.2013
- Author(s)
  Ito U, Hakamata Y, Watabe K, Oyanagi K.
- Journal Title
  
  Acta Neurochir Suppl
  
  Volume: 118 Pages: 23-29
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500498
[Journal Article] Cerebral ischemia model using mongolian gerbils-comparison between unilateral and bilateral carotid occlusion models.2013
- Author(s)
  1. Ito U, Hakamata Y, Yamaguchi　T, Ohno K.
- Journal Title
  
  Acta Neurochir Suppl
  
  Volume: 118 Pages: 17-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500498
[Journal Article] Sphingosine-1-phosphate receptor agonists suppress concanavalin A-induced hepatic injury in mice.2006
- Author(s)
  Kaneko T, Murakami T, Hakamata Y, Kawana H, Takahashi M, Yasue T, Kobayashi, E.
- Journal Title
  
  Biochem.Biophys.Res.Commun (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590625
[Journal Article] KRP-203, a novel synthetic immunosuppressant, prolongs graft survival and attenuates chronic rejection in rat skin and heart allografts.2005
- Author(s)
  Shimizu H, Takahashi M, Kaneko T, Murakami T, Hakamata Y, Kudou S, Kishi T, Fukuchi K, Iwanami S, Kuriyama K, Yasue T, Enosawa S, Matsumoto K, Takeyoshi I, Morishita Y, Kobayashi E.
- Journal Title
  
  Circulation 111
  
  Pages: 222-229
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590625
[Journal Article] A novel immunomodulator KRP-203 combined with cyclosporine prolonged graft survival and abrogated transplant vasculopathy in rat heart allografts.2005
- Author(s)
  Takahashi M, Shimizu H, Murakami T, Enosawa S, Suzuki C, Takeno Y, Hakamata Y, Kudou S, Izawa S, Yasue T, Kobayashi E.
- Journal Title
  
  Transplant Proc. 37
  
  Pages: 143-145
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590625
[Presentation] Development of a treatment for short bowel syndrome using small intestinal organoids2021
- Author(s)
  Shinya Sugimoto, Eiji Kobayashi, Masayuki Fujii, Yuki Ohta, Keiko Ishikawa, Kosaku Nanki, Yoji Hakamata, Takanori Kanai, Toshiro Sato
- Organizer
  The 16th Congress of European Crohn’s and Colitis Organisation (ECCO 2021)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03746
[Presentation] 短腸症候群に対するオルガノイドによる臓器リモデリング2020
- Author(s)
  杉本真也、小林英司、袴田陽二、金井隆典、佐藤俊朗
- Organizer
  第19回日本再生医療学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03746
[Presentation] スナネズミ自家骨髄由来間葉系幹細胞を用いた虚血性脳障害研究モデルの開発2015
- Author(s)
  大坂優衣、藤澤正彦、寺谷工、丸山基世、袴田陽二
- Organizer
  第14回日本再生医療学会
- Place of Presentation
  横浜市
- Year and Date
  2015-03-20
- Data Source
  KAKENHI-PROJECT-24500498
[Presentation] スナネズミおよびラット骨髄由来間葉系幹細胞の特性比較研究2014
- Author(s)
  大坂優衣、藤澤正彦、寺谷工、丸山基世、袴田陽二
- Organizer
  第61回日本実験動物学会総会
- Place of Presentation
  札幌市
- Year and Date
  2014-05-17
- Data Source
  KAKENHI-PROJECT-24500498
[Presentation] スナネズミ自家骨髄由来間葉系幹細胞を用いた脳虚血障害に対する神経保護作用の研究2014
- Author(s)
  大坂優衣、藤澤正彦、寺谷工、丸山基世、袴田陽二
- Organizer
  第１回獣医生命科学会
- Place of Presentation
  武蔵野市
- Year and Date
  2014-11-09
- Data Source
  KAKENHI-PROJECT-24500498
[Presentation] スナネズミの繁殖における膣内インピーダンスの有用性2014
- Author(s)
  荒井香南、大坂優衣、藤澤正彦、袴田陽二
- Organizer
  第61回日本実験動物学会総会
- Place of Presentation
  札幌市
- Year and Date
  2014-05-17
- Data Source
  KAKENHI-PROJECT-24500498
[Presentation] スナネズミ脳虚血障害に対するスナネズミ骨髄由来間葉系幹細胞の神経保護作用の研究2014
- Author(s)
  大坂優衣、藤澤正彦、寺谷工、丸山基世、袴田陽二
- Organizer
  第157回日本獣医学会学術集会
- Place of Presentation
  札幌市
- Year and Date
  2014-09-11
- Data Source
  KAKENHI-PROJECT-24500498
[Presentation] スナネズミの繁殖における膣壁インピーダンス値の有用性2014
- Author(s)
  荒井香南、大坂優衣、藤澤正彦、袴田陽二
- Organizer
  第１回獣医生命科学会
- Place of Presentation
  武蔵野市
- Year and Date
  2014-11-09
- Data Source
  KAKENHI-PROJECT-24500498
[Presentation] スナネズミ骨髄細胞由来間葉系幹細胞の特性解析2013
- Author(s)
  大坂優衣、寺谷　工、丸山基世、藤澤正彦、袴田陽二
- Organizer
  第29回日本獣医生命科学大学学術交流会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24500498
[Presentation] スナネズミを用いた新規脳虚血モデルの作製と応用2013
- Author(s)
  上田拓、大坂優衣、藤澤正彦、袴田陽二
- Organizer
  第2回動物保健看護系大学協会学術交流会
- Place of Presentation
  東京都武蔵野市
- Data Source
  KAKENHI-PROJECT-24500498
[Presentation] スナネズミ脳卒中モデルを用いた骨髄由来MSC細胞の神経保護作用の研究2013
- Author(s)
  大坂優衣、上田　拓、丸山基世、藤澤正彦、袴田陽二
- Organizer
  第86回実験動物コンファレンス
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24500498
[Presentation] Mongolian Gerbil Strains in Japan Demonstrate Diversity in Collateral Flow Pattern of Basilar Arteries2012
- Author(s)
  Yoji Hakamata, Masahiko FUJISAWA, Motoyo MARUYAMA, Umeo ITO
- Organizer
  The 5th Asian Federation of Laboratory Animal Science Associations Congress
- Place of Presentation
  Bangkok, Thailand
- Data Source
  KAKENHI-PROJECT-24500498
[Presentation] 脳卒中実験モデル動物の開発2012
- Author(s)
  袴田陽二
- Organizer
  第85回実験動物コンファレンス
- Place of Presentation
  東京都武蔵野市
- Invited
- Data Source
  KAKENHI-PROJECT-24500498
[Presentation] スナネズミの脳底動脈血管走行の多様性2012
- Author(s)
  袴田陽二、岡村恵理子、藤澤正彦、伊藤梅男
- Organizer
  第59日本実験動物学会総会
- Place of Presentation
  大分県別府市
- Data Source
  KAKENHI-PROJECT-24500498

1. KOBAYASHI Eiji (00245044)

# of Collaborated Projects: 6 results

# of Collaborated Products: 5 results
2. MURAKAMI Takashi (00326852)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
3. KANEKO Takashi (10254913)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
4. FUJISAWA Masahiko (10508873)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
5. YOSHIDA Shigeto (10296121)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. HOSOYA Yoshinori (30275698)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. FUJIMURA Akio (90156901)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. OKAMOTO Hiroaki (30177092)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. TANAKA Koichi (20115877)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. TAKAHASHI Masafumi (40296108)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. OSE Hirohiko (10324253)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. IKEDA Uichi (30221063)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. SUGIMOTO Shinya (20626387)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
14. 島田和幸 (90145128)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 多村知剛 (00571720)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 佐野元昭 (30265798)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 鈴木昌 (70265916)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 勝俣良紀 (80464832)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 佐藤俊朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 渡部和彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HAKAMATA YOJI 袴田 陽二

袴田 陽二 ハカマタ ヨウジ

HAKAMATA Yoji 袴田 陽二

Research Projects

Research Products

Co-Researchers

水素によるフェロトーシス抑制機構の解明と水素吸入療法の最適化

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional analysis of small intestinal epithelial organoid-based transplant graft

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of bio-imaging system for detecting neural stem cellPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of the lymphocyte-homing modulator against hepatitis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

心血管疾患におけるMIFの発現とその役割

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development for DNA vaccination against viral hepatitis recurrence after the liver transplantation using gene gun

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Cancer Gene Therapy with a Hand-Held Gene Gun

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] An organoid-based organ-repurposing approach to treat short bowel syndrome2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mannitol infusion immediately after reperfusion suppresses the development of focal cortical infarction after temporary cerebral ischemia in gerbils.2014

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Astrocytic involvement in the maturation phenomenon after temporary cerebral ischemia.2013

Author(s)

Journal Title

Data Source

[Journal Article] Cerebral ischemia model using mongolian gerbils-comparison between unilateral and bilateral carotid occlusion models.2013

Author(s)

Journal Title

Data Source

[Journal Article] Sphingosine-1-phosphate receptor agonists suppress concanavalin A-induced hepatic injury in mice.2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] KRP-203, a novel synthetic immunosuppressant, prolongs graft survival and attenuates chronic rejection in rat skin and heart allografts.2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] A novel immunomodulator KRP-203 combined with cyclosporine prolonged graft survival and abrogated transplant vasculopathy in rat heart allografts.2005

Author(s)

Journal Title

HAKAMATA YOJI 袴田陽二

袴田陽二ハカマタヨウジ

HAKAMATA Yoji 袴田陽二