Hirose Yutaka 広瀬豊

… Alternative Names

Researcher Number	00218851
Other IDs
Affiliation (Current)	2020: 富山大学, 学術研究部薬学・和漢系, 准教授
Affiliation (based on the past Project Information) *help	2015 – 2018: 富山大学, 大学院医学薬学研究部(薬学), 准教授 2010: University of Toyama, 大学院・医学薬学研究部(薬学), 准教授 2009 – 2010: University of Toyama, 大学院・医学薬学研究部, 准教授 2008: University of Toyama, 大学院・医学薬学研究部, 助教 2006: 富山大学, 大学院・医学薬学研究部, 助手 2006: 富山大学, 大学院医学薬学部, 助手 1999 – 2005: 金沢大学, がん研究所, 助手
Review Section/Research Field	Principal Investigator Biological Sciences / Molecular biology / Molecular biology Except Principal Investigator Biological Sciences / Virology
Keywords	Principal Investigator 転写 / RNAポリメラーゼII / mRNAプロセシング / リン酸化 / 遺伝子発現 / WWドメイン / 遺伝子発現調節 / アポトーシス / RNAプロセシング / gene expression … More Except Principal Investigator EBNA / EBウイルス / 癌ウイルス / 核蛋白 / 転写活性化 / メディエーター複合体 / リン酸化 / TFIIE / 細胞増殖 / LMP1 / 蛋白蛋白相互作用 / RNAポリメラーゼII(Pol II) / 基本転写因子TFIIH / CTD / コファクター / フォークヘッドドメイン / ルディエーター複合体 / CDK19 / 酵母2ハイブリッド法 / Rpb5 / 基本転写因子 / TFIIEβ / Rpb / MED15 / KIXドメイン / CDK8 / CDK11 / TFIIH / Rpb12 / Znフィンガードメイン / 補因子 / EBNA-LP / トランスフォーメーション / Epstein-Barr virus (EBV) / transactivation / cofactor / tumor virus / クロマチン / ヒストン / 癌化 / メディエーター / 転写開始複合体 / 遺伝子転写 / ヒストン翻訳後修飾 / ユビキチン化 / メチル化 Less

転写共役型新規mRNAメチル化酵素PCIF1によるmRNA代謝調節機構の解明Principal InvestigatorOngoing
- Principal Investigator
  
  広瀬豊
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  University of Toyama
Study of transcriptional cycle regulation via in vitro reconstitution
- Principal Investigator
  
  ITO Takashi
- Project Period (FY)
  2012 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Nagasaki University
Investigation of the mechanism by which novel phosphorylated RNA polymerase II-interacting factors coordinate processes required for gene expressionPrincipal Investigator
- Principal Investigator
  
  HIROSE Yutaka
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  University of Toyama
RNAポリメラーゼIICTDリン酸化制御による転写とRNAプロセシングの協調機構Principal Investigator
- Principal Investigator
  
  廣瀬豊 (広瀬豊)
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Toyama
  Kanazawa University
Unified crosstalk of signal transduction, chromatin regulation, and RNA processing by transcription complexes
- Principal Investigator
  
  OHKUMA Yoshiaki
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Toyama
リン酸化RNAポリメラーゼIIによるmRNAプロセシング過程の制御機構Principal Investigator
- Principal Investigator
  
  広瀬豊
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
Functional characterization of phosphorylated RNA polyrnerase II interacting factorsPrincipal Investigator
- Principal Investigator
  
  HIROSE Yutaka
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  KANAZAWA UNIVERSITY
転写とmRNAプロセシング過程を協調させている核内蛋白質間相互作用ネットワークPrincipal Investigator
- Principal Investigator
  
  広瀬豊
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
EBウイルス癌遺伝子産物EBNAとLMP1の協調作用による細胞増殖の分子機構
- Principal Investigator
  
  HARADA Shizuko
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute of Infectious Diseases
アポトーシスにおけるスプライシング制御Principal Investigator
- Principal Investigator
  
  広瀬豊
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
転写装置とmRNAプロセシング装置のクロストーク機構の解析Principal Investigator
- Principal Investigator
  
  広瀬豊
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kanazawa University
RNAポリメラーゼIIによるmRNAプロセシング調節機構の解析Principal Investigator
- Principal Investigator
  
  広瀬豊
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kanazawa University
転写とmRNAプロセシング過程を協調させている核内蛋白質間相互作用ネットワークPrincipal Investigator
- Principal Investigator
  
  広瀬豊
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
アポトーシスにおけるスプライシング制御Principal Investigator
- Principal Investigator
  
  広瀬豊
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
Characterization of novel proteins interacting with phosphorylated CTD of RNA polymerase IIPrincipal Investigator
- Principal Investigator
  
  HIROSE Yutaka
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  Kanazawa University
転写装置とmRNAプロセシング装置のクロストーク機構の解析Principal Investigator
- Principal Investigator
  
  広瀬豊
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kanazawa University
RNAポリメラーゼIIによるmRNAスプライシング調節機構の解析Principal Investigator
- Principal Investigator
  
  広瀬豊
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kanazawa University
MOLECULAR MECHANISM OF CO-ACTIVATION ACTIVITIES OF EPSTEIN-BARR VIRUS NUCLEARPROTEIN EBNA-LP
- Principal Investigator
  
  HARADA Shizuko
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  ST.MARIANNA UNIVERSITY SCHOOL OF MEDICINE
  Kanazawa University

All 2019 2018 2017 2016 2015 2014 2011 2010 2009 2008 2007 2006 2005

All Journal Article Presentation Book

[Book] III.RNAのプロセシングと編集:mRNAポリメラーゼII-CTDリン酸化制御による転写とmRNAプロセシングの共役「mRNAプログラム-多様性と非対称の獲得戦略」(編集:稲田利文,大野睦人, 蛋白質・核酸・酵素, 12月号増刊)2009
- Author(s)
  廣瀬豊
- Publisher
  共立出版
- Data Source
  KAKENHI-PROJECT-17054022
[Journal Article] Cap-specific terminal N6-methylation of RNA by an RNA polymerase Ⅱ-associated methyltransferase Cap.2019
- Author(s)
  Akichika S., Hirano S., Shichino Y., Suzuki T., Nishimasu H., Ishitani R., Sugita A., Hirose Y., Iwasaki S., Nureki O., and Suzuki T.
- Journal Title
  
  Science
  
  Volume: 363 Issue: 363 Pages: 6423-6423
- DOI
  10.1126/science.aav0080
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07282, KAKENHI-PROJECT-18K19141, KAKENHI-PUBLICLY-17H05592, KAKENHI-ORGANIZER-26113001, KAKENHI-PLANNED-26113003, KAKENHI-PROJECT-17H03640, KAKENHI-PROJECT-16H06276
[Journal Article] Mediator cyclin-dependent kinases upregulate transcription of inflammatory genes in cooperation with NF-kappaB and C/EBPbeta on stimulation of Toll-like receptor 9.2017
- Author(s)
  Yamamoto, S., Hagihara, T., Horiuchi, Y., Okui, A., Wani, S., Yoshida, T., Inoue, T., Tanaka, A., Ito, T., Hirose, Y., and Ohkuma, Y.
- Journal Title
  
  Genes Cells
  
  Volume: 22 Pages: 265-276
- DOI
  10.1111/gtc.12475
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-24118003, KAKENHI-PROJECT-15K01352, KAKENHI-PROJECT-15K18861, KAKENHI-PROJECT-17K07282, KAKENHI-PROJECT-17H04044
[Journal Article] Human SCP4 is a chromatin-associated CTD phosphatase and exhibits the dynamic translocation during erythroid differentiation2016
- Author(s)
  Wani S, Sugita A, Ohkuma Y, Hirose Y.
- Journal Title
  
  JOURNAL OF BIOCHEMISTRY
  
  Volume: 159 Pages: 111-120
- DOI
  10.1093/jb/mvw018
- NAID
  40020914038
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-25131704, KAKENHI-PLANNED-24118003
[Journal Article] Human Mediator MED17 Subunit Plays Essential Roles in Gene Regulation by Associating with both Transcription and DNA Repair Machineries.2015
- Author(s)
  Kikuchi, Y., Umemura, H., Nishitani, S., Iida, S., Fukasawa, R., Hayashi, H., Hirose, Y., Tanaka, A., Sugasawa, K. and Ohkuma, Y.
- Journal Title
  
  Genes Cells
  
  Volume: 20 Pages: 191-202
- DOI
  10.1111/gtc.12210
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-23116008, KAKENHI-PLANNED-24118003, KAKENHI-PROJECT-15K18861, KAKENHI-PUBLICLY-25131704
[Journal Article] Vertebrate Ssu72 regulates and coordinates 3'-end formation of RNAs transcribed by RNA polymerase II.2014
- Author(s)
  Wani, S., Yuda, M., Fujiwara, Y., Yamamoto, M., Harada, F., Ohkuma, Y., and Hirose, Y.
- Journal Title
  
  PLoS One
  
  Volume: 9 Pages: 1642-1648
- DOI
  10.1371/journal.pone.0106040
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-24118003, KAKENHI-PUBLICLY-25131704
[Journal Article] Transcription cofactor PC4 plays essential roles in collaboration with the small subunit of general transcription factor TFIIE.2014
- Author(s)
  Akimoto, Y., Yamamoto, S., Iida, S., Hirose, Y., Tanaka, A., Hanaoka, F., and Ohkuma, Y.
- Journal Title
  
  Genes to Cells
  
  Volume: 19 Pages: 879-890
- DOI
  10.1111/gtc.12187
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-24118003, KAKENHI-PUBLICLY-25131704
[Journal Article] A HIRA Complex Subunit Hip3 Plays an Important Role for Silencing of Meiosis-specific Genes in Schizosaccharomyces pombe2011
- Author(s)
  Mizuki F, Tanaka A, Hirose Y, Ohkuma Y
- Journal Title
  
  PLos One Vol.6, No.4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570162
[Journal Article] Enhancing recombinant protein production in human cell lines with a constitutive transport element and mRNA export proteins2011
- Author(s)
  Aihara Y, Fujiwara N, Yamazaki T, Kambe T, Nagao M, Hirose Y, Masuda S
- Journal Title
  
  J Biotechnol. 153
- NAID
  120003072129
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570162
[Journal Article] RNAポリメラーゼII-CTDリン酸化制御による遺伝子発現過程の協調機構2010
- Author(s)
  広瀬豊
- Journal Title
  
  生化学
  
  Volume: 82 Pages: 221-231
- Data Source
  KAKENHI-PROJECT-20570162
[Journal Article] RNAポリメラーゼII-CTDリン酸化制御による遺伝子発現過程の協調機構2010
- Author(s)
  広瀬豊
- Journal Title
  
  生化学 82巻、3号
  
  Pages: 221-231
- Data Source
  KAKENHI-PROJECT-20570162
[Journal Article] Prolyl isomerase Pin1 shares functional similarity with phosphorylated CTD interacting factor PCIF1 in vertebrate cells2009
- Author(s)
  Yunokuchi, I., Fan, H., Iwamoto, Y., Araki, C., Yuda, M., Umemura, H., Harada, F., Ohkuma, Y., Hirose, Y
- Journal Title
  
  Genes Cells 14
  
  Pages: 1105-1118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17054022
[Journal Article] RNAポリメラーゼII-CTDリン酸化制御による転写とmRNAプロセシングの共役2009
- Author(s)
  広瀬豊
- Journal Title
  
  蛋白質・核酸・酵素 54
  
  Pages: 2080-2085
- Data Source
  KAKENHI-PROJECT-20570162
[Journal Article] RNAポリメラーゼII-CTDリン酸化制御による転写とmRNAプロセシングの共役2009
- Author(s)
  広瀬豊
- Journal Title
  
  蛋白質・核酸・酵素 54巻
  
  Pages: 2080-2085
- Data Source
  KAKENHI-PROJECT-20570162
[Journal Article] Prolylisomerase Pin1 shares functional similarity with phosphorylated CTD interacting factor PCIF1 in vertebrate cells.2009
- Author(s)
  Yunokuchi, I., Fan, H., Iwamoto, Y., Araki, C., Yuda, M., Umemura, H., Harada, F., Ohkuma, Y., Hirose, Y.
- Journal Title
  
  Genes Cells 14
  
  Pages: 1105-1118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17054022
[Journal Article] Prolyl isomerase Pinl shares functional similarity with phosphorylated CTD interacting factor PCIF1 in vertebrate cells.2009
- Author(s)
  Yunokuchi I, Fan H, Iwamoto Y, Araki C, Yuda M, Umemura H, Harada F, Ohkuma Y, Hirose Y
- Journal Title
  
  Genes Cells 14
  
  Pages: 1105-1118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570162
[Journal Article] Human phosphorylated CTD-interacting protein, PCIF1, negatively modulates gene expression by RNA polymerase II.2008
- Author(s)
  Hirose Y, Iwamoto Y, Sakuraba K, Yunokuchi I, Harada F, Ohkuma Y
- Journal Title
  
  Biochem. Biophys. Res.Commun 369
  
  Pages: 449-455
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570162
[Journal Article] Mouse nucleolin binds to 4.5S RNA_H, a small noncoding RNA.2008
- Author(s)
  Hirose Y, Harada F
- Journal Title
  
  Biochem. Biophys. Res.Commun 365
  
  Pages: 62-68
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570162
[Journal Article] Human phosphorylated CTD-interacting protein, PCIF1, negatively modulates gene expression by RNA polymerase II2008
- Author(s)
  Hirose, Y., *Iwamoto, Y., Sakuraba, K., Yunokuchi, I., Harada, F., Ohkuma, Y
- Journal Title
  
  Biochem. Biophys. Res. Comm 69
  
  Pages: 449-455
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17054022
[Journal Article] Human phosphorylated CTD-interacting protein, PCIF1, negatively modulates gene expression by RNA polymerase II2008
- Author(s)
  Hirose, Y.
- Journal Title
  
  Biochem. Biophys. Res. Comm. 369
  
  Pages: 449-455
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570162
[Journal Article] Human phosphorylated CTD-interacting protein, PCIF1, negatively modulates gene expression by RNA polymerase II2008
- Author(s)
  Hirose, Y.
- Journal Title
  
  Biochem. Biophys. Res. Comm. 69
  
  Pages: 449-455
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17054022
[Journal Article] Human Mediator Kinase Subunit CDK11 Plays a Negative Role in Viral Activator VP16-dependent Transcription2008
- Author(s)
  Tsutsui, T., Umemura, H., Tanaka, A., Mizuki, F., Hirose, Y., Ohkuma, Y
- Journal Title
  
  Genes Cells 13
  
  Pages: 817-826
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17054022
[Journal Article] Mouse nucleolin binds to 4. 5S RNAh, a small noncoding RNA2008
- Author(s)
  Hirose, Y., Harada, F
- Journal Title
  
  Biochem. Biophys. Res. Commun 365
  
  Pages: 62-68
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17054022
[Journal Article] Human mediator kinase subunit CDK11 plays a negative role in viral activator VP16-dependent transcriptional regulation.2008
- Author(s)
  Tsutsui T, Umemura H, Tanaka A, Mizuki F, Hirose Y, Ohkuma Y
- Journal Title
  
  Genes Cells 13
  
  Pages: 817-826
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570162
[Journal Article] Phosphorylation of the C-terminal domain of RNA polymerase II plays central roles in the integrated events of eukaryotic gene expression2007
- Author(s)
  Hirose, Y., Ohkuma, Y
- Journal Title
  
  J. Biochem 122
  
  Pages: 481-489
- Data Source
  KAKENHI-PROJECT-17054022
[Journal Article] Phosphorylation of the C-terminal Domain of RNA Polymerase II Plays Central Roles in the Integrated Events of Eukaryotic Gene Expression2007
- Author(s)
  Hirose, Y.
- Journal Title
  
  J. Biochem. (in press)
- Data Source
  KAKENHI-PROJECT-17026013
[Journal Article] A kinase subunit of the human Mediator complex, CDK8, positively regulates transcriptional activation2007
- Author(s)
  Furumoto, T., Tanaka, A., Ito, M., Malik, S., Hirose, Y., Hanaoka, F., Ohkuma, Y
- Journal Title
  
  Genes Cells 12
  
  Pages: 119-132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17054022
[Journal Article] Phosphorylation of the C-terminal domain of RNA polymerase II plays central roles in the integrated events of eukaryotic gene expression.2007
- Author(s)
  Hirose, Y., Ohkuma, Y.
- Journal Title
  
  J. Biochem. (In press)
- Data Source
  KAKENHI-PROJECT-17054022
[Journal Article] mRNAの転写伸長・プロセシングのダイナミズム2005
- Author(s)
  広瀬豊
- Journal Title
  
  化学と生物 43巻・6号
  
  Pages: 366-374
- NAID
  10019044805
- Data Source
  KAKENHI-PROJECT-17026013
[Presentation] リン酸化CTD結合因子PCIF1による遺伝子発現調節2018
- Author(s)
  伊藤志帆，杉田愛，石黒尋保，田渕圭章，大熊芳明，廣瀬豊
- Organizer
  第20回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-17K07282
[Presentation] 基本転写因子による転写開始から伸長への移行の制御機構解析2018
- Author(s)
  平山翼,福岡瑞希,田中亜紀,廣瀬豊,大熊芳明
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17K07282
[Presentation] 転写と共役した選択的ポリ(A)付加調節の分子機構2018
- Author(s)
  竹田深雪，京角啓太，寺田公介，畑山光，大熊芳明，廣瀬豊
- Organizer
  第20回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-17K07282
[Presentation] 試験管内再構成系を用いたヒトメディエーター複合体Kinaseモジュールの機能解析2018
- Author(s)
  原子空，丹澤円, 林裕人，藤田智陽，飯田智，田中亜紀，廣瀬豊，大熊芳明
- Organizer
  日本生化学会北陸支部第36回大会
- Data Source
  KAKENHI-PROJECT-17K07282
[Presentation] リン酸化CTD結合因子PCIF1による遺伝子発現調節2018
- Author(s)
  伊藤志帆，杉田愛，柳澤奈月，石黒尋保，佐藤崇之，田渕圭章，大熊芳明，廣瀬豊
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K07282
[Presentation] 転写伸長因子DSIFのPol IIへのリクルートにおけるSpt5酸性領域とTFIIH p62の関与の検討2018
- Author(s)
  依田ちづる，平山翼，田中亜紀，廣瀬豊，大熊芳明
- Organizer
  日本薬学会北陸支部第130回例会
- Data Source
  KAKENHI-PROJECT-17K07282
[Presentation] Functional analysis of the kinase module of human Mediator complex using a baculovirus-insect cell expression system2018
- Author(s)
  Harako S, Hayasi H, Tanzawa M, Fujita C, Iida S, Tanaka A, Hirose Y, Ohkuma Y
- Organizer
  The Third International Symposium on Toyama-Asia-Africa Pharmaceutical Network
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07282
[Presentation] 転写伸長因子DSIFのPol IIへのリクルートにおけるSpt5の酸性領域とp62の関与の検討2018
- Author(s)
  平山翼，依田ちづる，田中亜紀，廣瀬豊，大熊芳明
- Organizer
  日本生化学会北陸支部第36回大会
- Data Source
  KAKENHI-PROJECT-17K07282
[Presentation] リン酸化CTD結合因子PCIF1による遺伝子発現調節機構2018
- Author(s)
  伊藤志帆，杉田愛，柳澤奈月，石黒尋保，田渕圭章，大熊芳明，廣瀬豊
- Organizer
  日本生化学会北陸支部第36回大会
- Data Source
  KAKENHI-PROJECT-17K07282
[Presentation] ユビキチン様ドメインを有する新規脱リン酸化酵素UBLCP1によるサイクリンE1遺伝子の発現制御機構の解析2018
- Author(s)
  車奏一郎，和仁翔太郎，加藤ありさ，加納未由希，石黒尋保，杉田愛，田渕圭章，大熊芳明，廣瀬豊
- Organizer
  日本薬学会北陸支部第130回例会
- Data Source
  KAKENHI-PROJECT-17K07282
[Presentation] リン酸化CTD結合因子PCIF1による遺伝子発現調節機構の解明2018
- Author(s)
  杉田愛,伊藤志帆,柳澤奈月,石黒尋保,田渕圭章,大熊芳明,廣瀬豊
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17K07282
[Presentation] 基本転写因子TFIIEとクロマチン構造変換複合体による転写制御機構2018
- Author(s)
  田中亜紀,山田佑里香,小林聡子,廣瀬豊,大熊芳明
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17K07282
[Presentation] 試験管内再構成系を用いたヒトメディエーター複合体Kinaseモジュールの機能解析2018
- Author(s)
  原子空,林裕人,藤田智陽,飯田智,廣瀬豊,大熊芳明
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17K07282
[Presentation] 転写と共役した選択的ポリ(A)付加調節機構2018
- Author(s)
  廣瀬豊，竹田深雪，京角啓太，寺田公介，畑山光，大熊芳明
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K07282
[Presentation] ユビキチン様ドメインを有するPol II-CTD脱リン酸化酵素による遺伝子発現制御2018
- Author(s)
  加藤ありさ，和仁翔太郎，加納未由希，石黒尋保，杉田愛，田渕圭章，大熊芳明，廣瀬豊
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K07282
[Presentation] 試験管内再構成系を用いたヒトメディエーター複合体Kinaseモジュールの機能解析2017
- Author(s)
  原子空,林裕人,藤田智陽,丹澤円香,飯田智,廣瀬豊,大熊芳明
- Organizer
  生命科学系学会合同年次大会ConBio2017
- Data Source
  KAKENHI-PROJECT-17K07282
[Presentation] 基本転写因子TFIIEの転写開始から伸長への移行段階における役割の解析2017
- Author(s)
  田中亜紀,福岡瑞希,平山翼,廣瀬豊,大熊芳明
- Organizer
  生命科学系学会合同年次大会ConBio2017
- Data Source
  KAKENHI-PROJECT-17K07282
[Presentation] 試験管内再構成系を用いたヒトメディエーター複合体Kinaseモジュールの機能解析2017
- Author(s)
  原子空,林裕人,藤田智陽,飯田智,廣瀬豊,大熊芳明
- Organizer
  第19回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-17K07282
[Presentation] リン酸化CTD結合因子PCIF1による遺伝子発現調節機構の解明2017
- Author(s)
  杉田愛,伊藤志帆,柳澤奈月,石黒尋保,佐藤崇之,田渕圭章,大熊芳明,廣瀬豊
- Organizer
  生命科学系学会合同年次大会ConBio2017
- Data Source
  KAKENHI-PROJECT-17K07282
[Presentation] ユビキチン様ドメインを有するPol II-CTD脱リン酸化酵素による遺伝子発現制御2017
- Author(s)
  杉田愛,和仁翔太郎,加藤ありさ,加納未由希,石黒尋保,田渕圭章,大熊芳明,廣瀬豊
- Organizer
  生命科学系学会合同年次大会ConBio2017
- Data Source
  KAKENHI-PROJECT-17K07282
[Presentation] リン酸化CTD結合因子PCIF1による遺伝子発現調節機構の解明2017
- Author(s)
  杉田愛,伊藤志帆,柳澤奈月,石黒尋保,佐藤崇之,田渕圭章,大熊芳明,廣瀬豊
- Organizer
  日本生化学会北陸支部第35回大会
- Data Source
  KAKENHI-PROJECT-17K07282
[Presentation] 基本転写因子による転写開始から伸長への移行の制御機構解析2017
- Author(s)
  福岡瑞希,田中亜紀,平山翼,廣瀬豊,大熊芳明
- Organizer
  第19回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-17K07282
[Presentation] ヒト転写メディエーター複合体kinaseモジュール構成サブユニットCDK8/19の新規結合因子の同定2017
- Author(s)
  藤田智陽,安倍光姫,山崎愛実,深澤力也,廣瀬豊,大熊芳明
- Organizer
  生命科学系学会合同年次大会ConBio2017
- Data Source
  KAKENHI-PROJECT-17K07282
[Presentation] 転写活性と共役した選択的ポリ(A)付加調節の分子機構2017
- Author(s)
  寺田公介,畑山光,西村和也,竹田深雪,大熊芳明,廣瀬豊
- Organizer
  第19回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-17K07282
[Presentation] リン酸化CTD結合因子PCIF1による遺伝子発現調節機構の解明2017
- Author(s)
  杉田愛,伊藤志穂,柳澤奈月,石黒尋保,佐藤崇之,田渕圭章,大熊芳明,廣瀬豊
- Organizer
  第19回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-17K07282
[Presentation] ヒト転写メディエーター複合体kinaseモジュール構成サブユニットCDK8/19の新規結合因子の同定2017
- Author(s)
  藤田智陽,安倍光姫,山崎愛実,深澤力也,廣瀬豊,大熊芳明
- Organizer
  第19回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-17K07282
[Presentation] ユビキチン様ドメインを有するPol II-CTD脱リン酸化酵素による遺伝子発現制御2017
- Author(s)
  和仁翔太郎,加藤ありさ,加納未由希,石黒尋保,杉田愛,田渕圭章,佐藤崇之,甲斐田大輔,大熊芳明,廣瀬豊
- Organizer
  第19回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-17K07282
[Presentation] リン酸化CTD結合因子PCIF1による遺伝子発現調節機構2016
- Author(s)
  杉田愛、柳澤奈月、石黒尋保、田渕圭章、大熊芳明、廣瀬豊
- Organizer
  第３９回日本分子生物学会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PLANNED-24118003
[Presentation] メディエーター複合体と神経細胞分化の関係2016
- Author(s)
  林　裕人、深澤力也、田中亜紀、廣瀬　豊、大熊芳明
- Organizer
  第89回　日本生化学会大会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PLANNED-24118003
[Presentation] ヒトメディエーター複合体Kinaseモジュール構成サブユニットCDK8/19の新規結合因子の同定2016
- Author(s)
  藤田智陽、安倍光姫、山崎愛実、深澤力也、廣瀬豊、大熊芳明
- Organizer
  第３９回日本分子生物学会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PLANNED-24118003
[Presentation] Dynamic Switch Mechanism of RNA Polymerase II by General Transcription Factor TFIIE from Transcription Initiation to the Transition Step from Initiation to Elongation2016
- Author(s)
  Yoshiaki Ohkuma, Takahide Nakamura, Yusuke Akimoto, Mizuki Fukuoka, Kumiko Sogawa, Yutaka Hirose, Aki Tanaka
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PLANNED-24118003
[Presentation] 基本転写因子TFIIEによる転写開始から伸長への移行の制御機構解析2016
- Author(s)
  中村　考秀、田中　亜紀、福岡　瑞希、廣瀬　豊、大熊　芳明
- Organizer
  第３９回日本分子生物学会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PLANNED-24118003
[Presentation] 脊椎動物リン酸化RNAポリメラーゼII結合因子PCIFIの機能解析2010
- Author(s)
  広瀬豊
- Organizer
  第32回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-20570162
[Presentation] 脊椎動物リン酸化RNAポリメラーゼII結合因子PCIF1の機能解析2010
- Author(s)
  広瀬豊
- Organizer
  第32回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  富山大学
- Data Source
  KAKENHI-PROJECT-20570162
[Presentation] Functional characterization of the vertebrate phosphorylated CTD-interacting protein PCIF1.2009
- Author(s)
  Hirose Y.
- Organizer
  11th Cold Spring Harbor Meeting on Mechanisms of Eukaryotic Transcription
- Place of Presentation
  Cold Spring Harbor(NY)
- Data Source
  KAKENHI-PROJECT-20570162
[Presentation] Functional characterization of the vertebrate phosphorylated CTD-interacting protein PCIF1.2009
- Author(s)
  Hirose Y.
- Organizer
  The 2009 CSH Meeting on Mechanisms of Eukaryotic Transcription
- Place of Presentation
  Cold Spring Harbor, NY, U.S.A.
- Data Source
  KAKENHI-PROJECT-17054022
[Presentation] Functional characterization of the vertebrate phosphorylated CTD-interacting protein PCIF12009
- Author(s)
  広瀬豊
- Organizer
  11th Cold Spring Harbor Meeting on Mechanisms of Eukaryotic Transcription
- Place of Presentation
  Cold Spring Harbor(NY)
- Data Source
  KAKENHI-PROJECT-20570162
[Presentation] 脊椎動物CTDフォスファターゼSsu72の遺伝子発現制御における機能2009
- Author(s)
  広瀬豊
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20570162
[Presentation] Functional characterization of the vertebrate phosphorylated CTD-interacting protein PCIF12009
- Author(s)
  Hirose, Y., Iwamoto, Y., Yunokuchi, I., Araki, C., Harada, H., Ho, K., Shuman, S., Mizuta, S., Ohkuma, Y
- Organizer
  The 2009 CSH Meeting on Mechanisms of Eukaryotic Transcription
- Place of Presentation
  Cold Spring Harbor, NY, USA
- Data Source
  KAKENHI-PROJECT-17054022
[Presentation] 脊椎動物リン酸化RNAポリメラーゼII制御因子の機能解析2009
- Author(s)
  広瀬豊, 岩本悠, 山本真也, 荒木千里, 河野隆英, 水口峰之, 原田文夫, 大熊芳明
- Organizer
  遺伝情報DECODE・冬のワークショップ(転写研究会共催)
- Place of Presentation
  湯沢
- Data Source
  KAKENHI-PROJECT-17054022
[Presentation] CTDフォスファターゼSsu72の遺伝子発現制御における機能2009
- Author(s)
  広瀬豊
- Organizer
  第11回日本RNA学会年会
- Place of Presentation
  新潟
- Data Source
  KAKENHI-PROJECT-20570162
[Presentation] 脊椎動物リン酸化RNAポリメラーゼII制御因子の機能解析2009
- Author(s)
  広瀬豊
- Organizer
  遺伝情報DECODE・冬のワークショップ
- Place of Presentation
  越後湯沢
- Data Source
  KAKENHI-PROJECT-20570162
[Presentation] Functional study of novel Mediator kinase subunit CDK11 in transcriptional regulation2008
- Author(s)
  Tsutsui T., Umemura H., Tanaka A., Mizuki F., Hirose Y., Ohkuma Y
- Organizer
  The 21st Naito Conference on Nuclear Dynamics and RNA [I]
- Place of Presentation
  Yatsugatake Royal Hotel, Yamanashi, Japan
- Data Source
  KAKENHI-PROJECT-17054022
[Presentation] Functional study on novel Mediator subunit CDK11 in transcriptional regulation2008
- Author(s)
  Tsutsui, T., Umemura, H., Tanaka, A., Mizuki, F., Hirose, Y., Ohkuma, Y
- Organizer
  8th EMBL Transcription Meeting
- Place of Presentation
  EMBL, Heidelberg, Germany
- Data Source
  KAKENHI-PROJECT-17054022
[Presentation] メディエーター複合体の新規キナーゼサブユニットの機能解析2008
- Author(s)
  梅村啓靖, 筒井大気, 田中亜紀, 廣瀬豊, 大熊芳明
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-17054022
[Presentation] hCDK8, a kinase subunit of human Mediator complex, plays a positive role in transcription2007
- Author(s)
  Umemura, H., Tsutsui, T., Nakatsubo, T., Tanaka, A., Hirose, Y., Ohkuma, Y
- Organizer
  10th Cold Spring Harbor Meeting on Cancer Cells
- Place of Presentation
  Cold Spring Harbor, NY, USA
- Data Source
  KAKENHI-PROJECT-17054022
[Presentation] 転写メディエーターから基本転写装置へのシグナリング2007
- Author(s)
  田中亜紀, 古元義, 廣瀬豊, 花岡文雄, 大熊芳明
- Organizer
  BMB2007ワークショップ「遺伝子発現に向けた核内シグナリング」
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-17054022
[Presentation] リン酸化RNAポリメラーゼII結合因子PCIF1による脊椎動物遺伝子発現調節2007
- Author(s)
  廣瀬豊, 荒木千里, 范紅, 湯の口いずみ, 湯田昌道, 原田文夫, 大熊芳明
- Organizer
  日本薬学会第127年会シンポジウム「核内情報受容から遺伝子発現への機構-その分子レベルでのアプローチ」
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-17054022
[Presentation] リン酸化RNAポリメラーゼII-CTD結合蛋白質PCIF1の機能解析2006
- Author(s)
  廣瀬豊, 湯田昌道, 湯の口いずみ, 范紅, 原田文夫, 大熊芳明
- Organizer
  第8回RNAミーティング
- Place of Presentation
  淡路島
- Data Source
  KAKENHI-PROJECT-17054022
[Presentation] Functional characterization of the phosphorylated RNA polymerase II interacting factor PCIF12006
- Author(s)
  Hirose, Y., Araki, C., Yuda, M., Yunokuchi, I., Fan, H., Harada, F., Ohkuma, Y
- Organizer
  RNA 2006 Izu "Functional RNAs and Regulatory Machinery"
- Place of Presentation
  Izunokuni, Japan1
- Data Source
  KAKENHI-PROJECT-17054022
[Presentation] Functional characterization of the phosphorylated RNA polymerase II interacting factor PCIF12006
- Author(s)
  Hirose, Y., Yuda, M., Yunokuchi, I., Fan, H., Ho, K., Shuman, S., Harada, F
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-17054022

1. OHKUMA Yoshiaki (70192515)

# of Collaborated Projects: 3 results

# of Collaborated Products: 27 results
2. HARADA Shizuko (10218646)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. TANAKA Aki (50432109)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
4. ITO Takashi (90306275)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 高野克彦 (50293303)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. INOUE Taskao

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. SUZUKI Takeo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. NISHIMASU Hiroshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. SUZUKI Tsutomu

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
10. ISHITANI Ryuichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 吉田徳幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 菅澤薫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 広瀬哲郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hirose Yutaka 広瀬 豊

広瀬 豊 ヒロセ ユタカ

HIROSE Yutaka 広瀬 豊

廣瀬 豊 ヒロセ ユタカ

Research Projects

Research Products

Co-Researchers

転写共役型新規mRNAメチル化酵素PCIF1によるmRNA代謝調節機構の解明Principal InvestigatorOngoing

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Study of transcriptional cycle regulation via in vitro reconstitution

Principal Investigator

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Research Institution

Investigation of the mechanism by which novel phosphorylated RNA polymerase II-interacting factors coordinate processes required for gene expressionPrincipal Investigator

Principal Investigator

Project Period (FY)

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RNAポリメラーゼIICTDリン酸化制御による転写とRNAプロセシングの協調機構Principal Investigator

Principal Investigator

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Review Section

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Unified crosstalk of signal transduction, chromatin regulation, and RNA processing by transcription complexes

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

リン酸化RNAポリメラーゼIIによるmRNAプロセシング過程の制御機構Principal Investigator

Principal Investigator

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Review Section

Research Institution

Functional characterization of phosphorylated RNA polyrnerase II interacting factorsPrincipal Investigator

Principal Investigator

Project Period (FY)

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転写とmRNAプロセシング過程を協調させている核内蛋白質間相互作用ネットワークPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

EBウイルス癌遺伝子産物EBNAとLMP1の協調作用による細胞増殖の分子機構

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

アポトーシスにおけるスプライシング制御Principal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

転写装置とmRNAプロセシング装置のクロストーク機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

RNAポリメラーゼIIによるmRNAプロセシング調節機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

転写とmRNAプロセシング過程を協調させている核内蛋白質間相互作用ネットワークPrincipal Investigator

Principal Investigator

Project Period (FY)

Hirose Yutaka 広瀬豊

広瀬豊ヒロセユタカ

HIROSE Yutaka 広瀬豊

廣瀬豊ヒロセユタカ