MATSUNO H 松野博明

Researcher Number	00219461
Affiliation (based on the past Project Information) *help	2005: 桐蔭横浜大, 教授 2003 – 2005: 桐蔭横浜大学, 先端医用工学センター, 教授 2000 – 2003: 富山医科薬科大学, 医学部, 助教授 1999: 富山医科薬科大学, 医学部, 講師 1996 – 1998: 富山医科薬科大学, 附属病院, 講師 1995: 富山医科薬科大学, 医学部, 助手 1993 – 1994: 富山医科薬科大学, 医学部・整形外科学, 助手
Review Section/Research Field	Principal Investigator Orthopaedic surgery / Orthopaedic surgery Except Principal Investigator Orthopaedic surgery / Orthopaedic surgery / Human pathology
Keywords	Principal Investigator SCIDマウス / 慢性関節リウマチ / Apoptosis / Rheumatoid Arthritis / 治療 / アポトーシス / 破骨細胞 / 関節リウマチ / 抗体治療 / コラーゲン誘導関節炎 … More / Matrix Metalloproteinase / Humanized Antibody / Monocronal Antibody / Cartilage / Synovium / SCID-HuRAg mouse / モノクローナル抗体 / T細胞 / リンパ球 / テロメア / テロメラーゼ / 慢性間接リウマチ / マトリックスメタロプロテアーゼ / ヒト化抗体 / モノクロナール抗体 / 軟骨 / 滑膜 / SCID-HuRAgマウス / Cytikine / Joint destruction / Treatment / Interleikin-6 / Collagen Induce Arthritis / SCID-Hu RAg mouse / アポプトーシス / 滑膜組織 / サイトカイン / 関節破壊 / インターロイキン-6 / SCID-Hu RAgマウス / ピットホール / dentin / カルパイン / 抗カルパスタチン抗体 / Tumor Necrosis Factor / インターロイキン-1β / T-リンパ球 / 単球 / インターロイキン-18 / in situ hybridization / サブスタンスP受容体 / リンパ球サブセット / T細胞受容体 … More Except Principal Investigator 関節リウマチ / Rheumatoid Arthritis / collagen / gene / repair / cartilage / コラーゲン / 遺伝子 / 修復 / 軟骨 / 破骨細胞 / chaperon / heat-shock protein / シャペロン / 熱ショックタンパク質 / anti-TNF antibody / osteoclast / 抗TNFα抗体 / mesenchymal cell / 転写因子 / 間葉系細胞 / Immunohistochemistry / Immunology / Intervertebral disc / Monoclonal antibody / 免疫組織化学 / 免疫機構 / 椎間板変性 / モノクローナル抗体 / 破骨細胞形成制御因子(OCIF) / 破骨細胞形成抑制因子 / 骨破壊 / SCIDマウス / 動物モデル / 軟骨細胞 / 骨芽細胞 / 細胞寿命 / 細胞老化 / テロメラーゼ / テロメア / 再生医学 Less

Effects of anti TNF α antibody (infliximab) plus MTX on SCID-HuRAg-pit model
- Principal Investigator
  
  OCHIAI Akira
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Toin University of Yokohama
Development of the method in treatment of Rheumatoid Arthritis (RA) with heat-shock protein, chaperon
- Principal Investigator
  
  YOSHIDA Kaoru
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Toin University of Yokohama
RAにおける生物製剤の臨床応用を目指した創薬開発Principal Investigator
- Principal Investigator
  
  松野博明
- Project Period (FY)
  2003 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Toin University of Yokohama
ヒト病態解析のためのヒト組織のSCIDマウスへの移植による新しいモデルの開発-破骨細胞形成抑制因子(OCIF)のSCID-Hu Ragモデルでの評価-
- Principal Investigator
  
  澤井高志 (沢井高志)
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Human pathology
- Research Institution
  Iwate Medical University
Genes associated with cartilage differentiation and their application to cartilage repair
- Principal Investigator
  
  KIMURA Tomoatsu
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  TOYAMA MEDICAL AND PHARMACEUTICAL UNIVERSITY
骨関節組織の老化変性の発生機序と、細胞寿命・老化の克服による関節再生修復法の開発
- Principal Investigator
  
  YUDOH Kazuo
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Toyama Medical and Pharmaceutical University
Regulation of cartilage destruction using tissue-specific expression system
- Principal Investigator
  
  KIMURA Tomoatsu
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  TOYAMA MEDICAL AND PHARMACEUTICAL UNIVERSITY
Novel humanized anti-Fas Mab provide a new treatment for Rheumatoid ArthiritisPrincipal Investigator
- Principal Investigator
  
  MATSUNO Hiroaki
- Project Period (FY)
  1999 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  TOYAMA MEDICAL AND PHARMACEUTICAL UNIVERSITY
Role of Apoptosis in Patients with Rheumatoid ArthritisPrincipal Investigator
- Principal Investigator
  
  MATSUNO Hiroaki
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Toyama Medical and Pharmaceutical University
ヒト慢性関節リウマチ患者滑膜組織のSCIDマウスへの移入とリウマチ発症機構の解明Principal Investigator
- Principal Investigator
  
  松野博明
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Toyama Medical and Pharmaceutical University
慢性関節リウマチ患者滑膜組織のおけるサブスタンスP受容体mRNAの局在Principal Investigator
- Principal Investigator
  
  松野博明
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Toyama Medical and Pharmaceutical University
モノクローナル抗体による慢性関節リウマチの進展制御に関する実験的治療研究Principal Investigator
- Principal Investigator
  
  松野博明
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Toyama Medical and Pharmaceutical University
Immunological effect of CB-11mAb on intervertebral disc degeneration
- Principal Investigator
  
  TSUJI Haruo
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  TOYAMA MEDICAL AND PHARMACEUTICAL UNIVERSITY

All 2005 2004

All Journal Article

[Journal Article] 抗カルパスタチン抗体(ACA)2005
- Author(s)
  松野博明, 落合晃, 岩城(江川)祥子, 渡辺泰裕
- Journal Title
  
  日本臨床-関節リウマチ成因研究から治療の新時代へ- 63(9)
  
  Pages: 344-350
- Data Source
  KAKENHI-PROJECT-17591600
[Journal Article] Interleukin-18 Enhances Monocyte Tumor Necrosis Factor α and Interleukin-1 β Production Induced by Direct Contact With T Lymphocytes2004
- Author(s)
  Sheng-Ming Dai, Matsuno H, Nakamura H, Nishioka K, Yudoh K
- Journal Title
  
  Arthritis Rheum. 50(2)
  
  Pages: 432-443
- Data Source
  KAKENHI-PROJECT-15390454
[Journal Article] The role of Fas-mediated apoptosis after traumatic spinal cord injury.2004
- Author(s)
  Yoshino O, Matsuno H, Yudoh K, Abe Y, Sawai T, Uzuki M, et al.
- Journal Title
  
  Spine 29(13)
  
  Pages: 1394-1404
- NAID
  10017379024
- Data Source
  KAKENHI-PROJECT-14657050
[Journal Article] 関節リウマチをめぐる基礎的研究関節リウマチの骨・軟骨破壊機序.2004
- Author(s)
  松野博明, 宇月美和
- Journal Title
  
  現代医療 36(3)
  
  Pages: 686-696
- Data Source
  KAKENHI-PROJECT-14657050
[Journal Article] High diagnostic value of anticalpastatin autoantibodies in rheumatoid arthritis detected by ELISA using human erythrocyte calpastain as antigen.2004
- Author(s)
  Iwaki-Egawa S, Matsuno H, Yudoh K, Nakazawa F, Miyazaki K, Ochiai A, Hirohata S, Shimizu M, Watanabe Y
- Journal Title
  
  J. Rheumatol. 31(1)
  
  Pages: 17-22
- Data Source
  KAKENHI-PROJECT-15390454

1. YUDOH Kazuo (60272928)

# of Collaborated Projects: 6 results

# of Collaborated Products: 3 results
2. KIMURA Tomoatsu (80167379)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. TSUJI Haruo (90009449)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. ISHIHARA H (30242499)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. YONEHARA Shin (00124503)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. MORITA Yuji (30313604)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. MATSUSHITA Isao (80345587)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. WAKITANI Shigeyuki (70243243)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. OCHIAI Akira (60398972)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. GOTO Makoto (00170465)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. YOSHIDA Kaoru (70398973)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 長田龍介 (40293310)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 澤井高志 (00125577)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. 黒瀬顕 (70244910)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 宇月美和 (50305992)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
16. 吉田昌明 (80210722)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

MATSUNO H 松野 博明

Research Projects

Research Products

Co-Researchers

Effects of anti TNF α antibody (infliximab) plus MTX on SCID-HuRAg-pit model

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of the method in treatment of Rheumatoid Arthritis (RA) with heat-shock protein, chaperon

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

RAにおける生物製剤の臨床応用を目指した創薬開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ヒト病態解析のためのヒト組織のSCIDマウスへの移植による新しいモデルの開発-破骨細胞形成抑制因子(OCIF)のSCID-Hu Ragモデルでの評価-

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Genes associated with cartilage differentiation and their application to cartilage repair

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

骨関節組織の老化変性の発生機序と、細胞寿命・老化の克服による関節再生修復法の開発

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of cartilage destruction using tissue-specific expression system

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Novel humanized anti-Fas Mab provide a new treatment for Rheumatoid ArthiritisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of Apoptosis in Patients with Rheumatoid ArthritisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ヒト慢性関節リウマチ患者滑膜組織のSCIDマウスへの移入とリウマチ発症機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

慢性関節リウマチ患者滑膜組織のおけるサブスタンスP受容体mRNAの局在Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

モノクローナル抗体による慢性関節リウマチの進展制御に関する実験的治療研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Immunological effect of CB-11mAb on intervertebral disc degeneration

Principal Investigator

Project Period (FY)

Research Category

MATSUNO H 松野博明

[Journal Article] 関節リウマチをめぐる基礎的研究関節リウマチの骨・軟骨破壊機序.2004