HARA Yasushi 原康

… Alternative Names

原康ハラヤスシ

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Researcher Number	00228628
Other IDs
Affiliation (Current)	2025: 日本獣医生命科学大学, 獣医学部, 教授
Affiliation (based on the past Project Information) *help	2011 – 2019: 日本獣医生命科学大学, 獣医学部, 教授 2010: 日本獣医生命科学大学, 日本獣医生命科学大学獣医学部, 准教授 2010: 日本獣医生命科学大学, 獣医学部, 助教授 2009: Nippon Veterinary and Life Science University, 獣医学部, 准教授 2007: Nippon Veterinary and Science University, Department of Surgery, Associate Professor 2004 – 2006: 日本獣医畜産大学, 獣医学部, 助教授
Review Section/Research Field	Principal Investigator Clinical veterinary science / Veterinary medical science Except Principal Investigator Orthopaedic surgery
Keywords	Principal Investigator Cushing disease / MRI / Cushing病 / グルココルチコイド受容体 / 下垂体 / 副腎皮質機能亢進症 / mitral valve / cortisol / 心筋バイオマーカー / 心内腔容積 … More / 三次元心エコー / 高コルチゾール血症 / 心筋線維化 / 心筋肥大 / 高コルチゾル血症 / クッシング症候群 / Pituitary gland / Pituitary adenoma / Mitotane / Hyperadrenocorticocism / Dog / ACTH / corticotroph / Negative feedback / Nelson's syndrome / cushing's syndrome / 副腎皮質抑制 / op'-DDD / Cushing病(クッシング病) / 犬 / 下垂体腫瘍 / 副腎皮質機能抑制モデル / オペプリム / Nelson症候群 / CRH / コルチゾール分泌抑制薬 / ACTH産生腺腫 / コルチゾール / ステロイド代謝酵素 / コルチゾール抵抗性 / クッシング病 / 犬下垂体ACTH産生腺腫 … More Except Principal Investigator 椎間板変性 / MMP-3 / TWEAK / 抗サイトカイン療法 / 椎間板変性犬モデル / 炎症賦活メカニズム / マクロファージ / 椎間板器官培養 / PAR-1 / Degeneration of intervertebral disc / TEWAK / angiogenesis / VEGF / TNF-α / MCP-1 Less

Effects of cortisol on catabolism of canine mitral valvePrincipal Investigator
- Principal Investigator
  
  Hara Yasushi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Veterinary medical science
- Research Institution
  Nippon Veterinary and Life Science University
Clarification of age-related changes in intervertebral discs and development of new anti-cytokine therapy
- Principal Investigator
  
  HARO Hirotaka
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  University of Yamanashi
The effect of trilostane on the proliferation of canine pituitary corticotroph adenomaPrincipal Investigator
- Principal Investigator
  
  HARA Yasushi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Clinical veterinary science
- Research Institution
  Nippon Veterinary and Life Science University
Research on the pathophysiology of resistance to glucocorticoid feedback in canine pituitary ACTH-secreting adenomas.Principal Investigator
- Principal Investigator
  
  HARA Yasushi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Clinical veterinary science
- Research Institution
  Nippon Veterinary and Life Science University
Molecular biologic approach to elucidate intervertebral disc degeneration and establishment of new treatment
- Principal Investigator
  
  HARO Hirotaka
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  University of Yamanashi
The mechanism of low back pain and establish for new strategy of treatment
- Principal Investigator
  
  HARO Hirotaka
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  University of Yamanashi
Morphological and functional changes of pituitary corticotrophs in the experimental dog under inhibition of the adrenal cortex.Principal Investigator
- Principal Investigator
  
  HARA Yasushi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Clinical veterinary science
- Research Institution
  Nippon Veterinary & Animal Science University

All 2020 2019 2015 2014 2011 2010 2009 2006 Other

All Journal Article Presentation

[Journal Article] Transsphenoidal Surgery in Canines: Safety, Efficacy and Patient Selection.2020
- Author(s)
  Yasushi, Hara
- Journal Title
  
  Veterinary Medicine: Research and Reports
  
  Volume: 11 Pages: 1-14
- DOI
  10.2147/vmrr.s175995
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08114
[Journal Article] Ki-67 and minichromosome maintenance-7(MCM7) expression in canine pituitary corticotroph adenomas2011
- Author(s)
  石野寛和、原康、竹腰進(以下4名)
- Journal Title
  
  Domestic Animal Endocrinology
  
  Volume: 41巻 Issue: 4 Pages: 207-213
- DOI
  10.1016/j.domaniend.2011.07.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580394
[Journal Article] Efficacy of Transsphenoidal Surgery on Endocrinological Status and Serum Chemistry Parameters in Dogs with Cushing's Disease2010
- Author(s)
  原康
- Journal Title
  
  J Vet Med Sci.
  
  Volume: 72 Pages: 397-404
- NAID
  40017112790
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580394
[Journal Article] Efficacy of Transsphenoidal Surgery on Endocrinological Status and Serum Chemistry Parameters in Dogs with Cushing's Disease2010
- Author(s)
  原康、手嶋隆洋、垰田高広、(以下7名)
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 72 Issue: 4 Pages: 397-404
- DOI
  10.1292/jvms.09-0367
- NAID
  130000134559
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580394
[Journal Article] Efficacy of Transsphenoidal Surgery on Endocrinological Status and Serum Chemistry Parameters in Dogs with Cushing's Disease2010
- Author(s)
  原康
- Journal Title
  
  J Vet Med Sci. 72
  
  Pages: 397-404
- NAID
  40017112790
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580394
[Journal Article] Expression of genes related to corticotropin production and glucocorticoid feedback in corticotroph adenomas of dogs with Cushing's disease2009
- Author(s)
  手嶋隆洋、原康、竹腰進、(以下3名)
- Journal Title
  
  Domestic Animal Endocrinology
  
  Volume: 36巻 Issue: 1 Pages: 3-12
- DOI
  10.1016/j.domaniend.2008.08.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580394
[Journal Article] Functional and morphological changes in the hypothalamus-pituitary posterior lobe system after hypophysectomy in the dog.2006
- Author(s)
  Takahiro TAODA, Yasushi HARA, Hiroyuki MASUDA, Yoshinori NEZU, Naoko SANNO, Akira TERAMOTO, Susumu TAKEKOSHI, Robert Y.OSAMURA, Masahiro TAGAWA
- Journal Title
  
  Journal of Veterinary Medical Science 68(1)
  
  Pages: 1-7
- NAID
  130000448077
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16580269
[Journal Article] Effect of mitotane on pituitary corticotrophs in clinically normal dogs.2006
- Author(s)
  Takahiro TAODA, Yasushi HARA, Susumu TAKEKOSHI, Johbu ITOH, Akira TERAMOTO, Robert Y.OSAMURA, Masahiro TAGAWA
- Journal Title
  
  American Journal of Veterinary Reseach (In press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16580269
[Journal Article] Functional and morphological changes in the hypothalamus-pituitary posterior lobe system after hypophysectomy in the dog.2006
- Author(s)
  Takahiro TAODA, Yasushi HARA, Hiroyuki MASUDA, Yoshinori NEZY, Naoko SANNO, Akira TERAMOTO, Susumu TAKEKOSHI, Robert Y.OSAMURA, Masahiro TAGAWA
- Journal Title
  
  Journal of Veterinary Medical Science 68・1
  
  Pages: 1-7
- NAID
  130000448077
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16580269
[Journal Article] Effect of mitotane on pituitary corticotrophs in clinically normal dogs.2006
- Author(s)
  Takahiro TAODA, Yasushi HARA, Susumu TAKEKOSHI, Johbu ITOH, Akira TERAMOTO, Robert Y.OSAMURA, Masahiro TAGAWA
- Journal Title
  
  American Journal of Veterinary Research (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16580269
[Presentation] 健常ビーグル犬に対する高用量プレドニゾロン長期投与が心形態に及ぼす影響2019
- Author(s)
  田中祥代、渋谷比斗美、鈴木周二、神野信夫、余戸拓也、原田恭治、佐藤朝香、原康
- Organizer
  第162回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08114
[Presentation] 健常ビーグル犬に対する高用量プレドニゾロン長期投与が心筋組織に及ぼす影響2019
- Author(s)
  渋谷比斗美、田中祥代、鈴木周二、神野信夫、余戸拓也、原田恭治、佐藤朝香、原康
- Organizer
  第162回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08114
[Presentation] 小動物獣医療の脳神経外科手術2015
- Author(s)
  原　康
- Organizer
  第29回神奈川脳腫瘍フォーラム
- Place of Presentation
  横浜崎陽軒本店
- Year and Date
  2015-03-13
- Invited
- Data Source
  KAKENHI-PROJECT-24580466
[Presentation] 小動物獣医療の脳神経外科手術2015
- Author(s)
  原　康
- Organizer
  第22回文京脳腫瘍研究会
- Place of Presentation
  東京ガーデンパレス
- Year and Date
  2015-02-02
- Invited
- Data Source
  KAKENHI-PROJECT-24580466
[Presentation] 小動物獣医療の脳神経外科手術2014
- Author(s)
  原　康
- Organizer
  第４回千駄木脳腫瘍研究会
- Place of Presentation
  東京ガーデンパレス
- Year and Date
  2014-06-06
- Invited
- Data Source
  KAKENHI-PROJECT-24580466
[Presentation] ACTH産生腺腫罹患犬および下垂体過形成モデル犬から採取した下垂体組織におけるBMP4の発現に関する検討2014
- Author(s)
  佐藤朝香、原康
- Organizer
  間脳・下垂体・副腎系研究会
- Place of Presentation
  ロシュ・ダイアグノスティック株式会社
- Data Source
  KAKENHI-PROJECT-24580466
[Presentation] 下垂体腫瘍の外科的治療2014
- Author(s)
  原康
- Organizer
  日本獣医師会学術集会年次大会
- Place of Presentation
  幕張メッセ（国際会議場）
- Invited
- Data Source
  KAKENHI-PROJECT-24580466
[Presentation] 下垂体切除術2011
- Author(s)
  原康
- Organizer
  獣医麻酔外科学会
- Place of Presentation
  大宮ソニックシティ
- Year and Date
  2011-06-11
- Data Source
  KAKENHI-PROJECT-21580394
[Presentation] 頭蓋内髄膜腫術後管理2010
- Author(s)
  原康
- Organizer
  獣医麻酔外科学会
- Place of Presentation
  大宮ソニックシティ
- Year and Date
  2010-08-01
- Data Source
  KAKENHI-PROJECT-21580394
[Presentation] Cushing病罹患犬における内因性血漿ACTH濃度およびCRH負荷試験と下垂体サイズに関する検討
- Author(s)
  佐藤朝香、石野寛和、澤田治美、神野信夫、原田恭治、余戸拓也、原康
- Organizer
  獣医麻酔外科学会
- Place of Presentation
  大宮ソニックシティ
- Year and Date
  2014-06-14 – 2014-06-15
- Data Source
  KAKENHI-PROJECT-24580466
[Presentation] ACTH産生腺腫罹患犬および下垂体過形成モデル犬から採取した下垂体組織におけるBMP4の発現に関する検討
- Author(s)
  佐藤朝香、神野信夫、原田恭治、余戸拓也、原康
- Organizer
  獣医神経病学会
- Place of Presentation
  札幌市教育文化会館
- Year and Date
  2014-07-05 – 2014-07-06
- Data Source
  KAKENHI-PROJECT-24580466

1. HARO Hirotaka (10313264)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. NAKAO Atsushito (80317445)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. TEKADA Shu (30376727)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. HAMADA Yoshiki (80096544)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. TAGAWA Masahiro (90097072)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
6. NEZU Yoshinori (20350176)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. ASOU Yoshinori (50345279)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. TAKAYAMA Yoshihiro (20596994)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 安藤隆 (10377492)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 高橋淳 (60345741)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 大場哲郎 (70456490)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

HARA Yasushi 原 康

原 康 ハラ ヤスシ

Research Projects

Research Products

Co-Researchers

Effects of cortisol on catabolism of canine mitral valvePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Clarification of age-related changes in intervertebral discs and development of new anti-cytokine therapy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The effect of trilostane on the proliferation of canine pituitary corticotroph adenomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Research on the pathophysiology of resistance to glucocorticoid feedback in canine pituitary ACTH-secreting adenomas.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular biologic approach to elucidate intervertebral disc degeneration and establishment of new treatment

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The mechanism of low back pain and establish for new strategy of treatment

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Morphological and functional changes of pituitary corticotrophs in the experimental dog under inhibition of the adrenal cortex.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Transsphenoidal Surgery in Canines: Safety, Efficacy and Patient Selection.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ki-67 and minichromosome maintenance-7(MCM7) expression in canine pituitary corticotroph adenomas2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Efficacy of Transsphenoidal Surgery on Endocrinological Status and Serum Chemistry Parameters in Dogs with Cushing's Disease2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Efficacy of Transsphenoidal Surgery on Endocrinological Status and Serum Chemistry Parameters in Dogs with Cushing's Disease2010

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Efficacy of Transsphenoidal Surgery on Endocrinological Status and Serum Chemistry Parameters in Dogs with Cushing's Disease2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Expression of genes related to corticotropin production and glucocorticoid feedback in corticotroph adenomas of dogs with Cushing's disease2009

Author(s)

Journal Title

DOI

Data Source

HARA Yasushi 原康

原康ハラヤスシ

[Presentation] 頭蓋内髄膜腫術後管理2010