sugimoto hiroyuki 杉本博之

… Alternative Names

杉本博之スギモトヒロユキ

Sugimoto Hiroyuki 杉本博之

SUGIMOTO Hiroyuki 杉本博之

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Researcher Number	00235897
Other IDs
Affiliation (Current)	2025: 獨協医科大学, 医学部, 名誉教授
Affiliation (based on the past Project Information) *help	2020 – 2023: 獨協医科大学, 医学部, 教授 2012 – 2018: 獨協医科大学, 医学部, 教授 2005 – 2007: 獨協医科大学, 医学部, 教授 2004: 群馬大学, 医学系研究科, 助教授 2003: 群馬大学, 医学部, 助教授 … More 2000 – 2001: 群馬大学, 医学部, 助教授 1997 – 1999: 群馬大学, 医学部, 講師 1992 – 1996: 群馬大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Pathological medical chemistry / General medical chemistry / Basic Section 48040:Medical biochemistry-related / Pathological medical chemistry Except Principal Investigator Basic Section 54040:Metabolism and endocrinology-related / Medium-sized Section 58:Society medicine, nursing, and related fields / Functional biochemistry / General medical chemistry / Pathological medical chemistry / Biological Sciences
Keywords	Principal Investigator オキシステロール / リゾホスホリパーゼ / ホスファチジン酸 / リゾホスファチジルコリン / コレステロール25-ヒドロキシラーゼ / PKC / M-CSF / RAW264 / Ets / コレステロール … More / ホスファチジルエタノールアミン / 25-ヒドロキシコレステロール / HMG-CoAレダクターゼ / シチジリルトランスフェラーゼ / ホスホエタノールアミン / トランスアシラーゼ / リゾホスファチジン酸 / 酸化コレステロール / グルカゴン / インスリン様成長因子 / コレステロールヒドロキシラーゼ / シトクロム P400 46a1 / シトクロムP450 46A1 / N2A細胞 / T98G細胞 / NIH3T3細胞 / 24S-ヒドロキシコレステロール / Cytochrome P450 46a1 / IGF-II / Neuroblastoma / Fetuin-B / Cyp46A1 / シチジルトランスフェラーゼ / コレステロール25ヒドロキシラーゼ / 25－ヒドロキシコレステロール / Fetal bovine serum / コレステロール25－ヒドロキシラーゼ / ET / コレステロール25ヒドロキシラーぜ / 25ーヒドロキシコレステロール / Phosohatidvlethannlamine / CTP : Phosohoethanolamine Cytidvlvltransferase / Phosphatidvicholine / CTP : Phosohocholine Cytidvlvltransferase / NES / NLS / Ets-1 / CTP : Phosphocholine Cytidylyltransferase α / 細胞周期 / CTP : Phosphoethanolamine Cidylyltransferase / Net / Ets1 / CTP : Phosphocholine cytidylyltransferase α / CTP:Phosahocholine Cytidylyltransferase / CTP:Phosphoethanolamine Cytidylyltransferase / ホスファチジルコリン / CTP:Phosphocholine Cytidylyltransferase / YY1 / HMG-CoA reductase / 25-hydroxycholesterol / Cytidylyltransferase / CTP:phosphoethanolamine / Phosphatidylethanolamine / Yin Yang1 / NF-Y / アンキリンリピート / リゾホスファケジルコリン / アンキリンリピート / パルミチン酸 / プロティンキナーゼZ / ホスホリパーゼD / ホスホリパーゼA2 / リゾホスホリパーゼ・トランスアシラーゼ … More Except Principal Investigator ホスホリパーゼD / リゾホスホリパーゼ / lysophospholipase / phospholipase D / クローニング / ショウジョウバエ / ホスファチジルコリン / ホスファチジン酸 / cDNA / cloning / 細胞内情報伝達 / NO合成酵素 / アシル蛋白チオエステラーゼ / リゾホスファチジルセリン / secretion / peptide / hormone / pituitary / ペプチドホルモン / ACTH / オートファジー / 下垂体腫瘍 / 疫学 / 運動 / 糖尿病 / Muse細胞 / NO synthase / acyl-protein thioesterase / Drosophila melanogaster / rat / rPLD2 / rPLD1 / 阻害因子 / PHドメイン / ラット / G protein / intracellular signal transduction / phosphatidylcholine / 転写後調節 / HL-60細胞 / Gタンパク質 / lysophosphatidylcholine / phosphatidic acid / enzyme purification / signal transduction / cell growth / phosphatidylcholine metabolism / コリンキナーゼ / リゾホスファチジルコン / リゾホスファチジルコリン / 酵素精製 / シグナル伝達 / 細胞増殖 / ホスファチジルコリン代謝 / 血小板活性化因子 / ホスホリパーゼ / オーファン受容体 / 酸化遊離脂肪酸 / リン脂質生合成 / 5-リポキシゲナーゼ / 2-アラキドノイルグリセロール / リゾホスファチジン酸 / ロイコトリエン / Gタンパク質共役型受容体 / 生理活性脂質 / アスパラギナーゼ / アンキリンリピート / ロイシンジッパー / エステラーゼ / アシルトランスフェラーゼ / リゾリン脂質 / 胚発生 / 脂質 / リパーゼ / 複眼形成 / アナンダミド / アラキドン酸 / 発生 / 脳 / 組織分布 / 低分子Gタンパク質 / ホスファチジルイノシトールビスリン酸 / PLD2 / PLD1 / 神経情報伝達 / ホスホリパ-ぜD / 乳癌 / ジメチルベンシアントラセン / ras / 情報伝達 Less

Exploratory research for Muse cell function and epidemiology in diabetes patients
- Principal Investigator
  
  小橋元
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  Dokkyo Medical University
Uncovering the maturation process of the pituitary hormoen, ACTH.
- Principal Investigator
  
  佐藤元康
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Dokkyo Medical University
インスリン様成長因子等による側鎖型オキシステロール産生調節を介した新規情報伝達Principal Investigator
- Principal Investigator
  
  杉本博之
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Dokkyo Medical University
Identification of regulation factor for oxysterol production in FBS and its nobel signal transductionPrincipal Investigator
- Principal Investigator
  
  Sugimoto Hiroyuki
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Dokkyo Medical University
Identification of novel transcriptional factors and their roles for homeostasis of lipid composition of cell membranePrincipal Investigator
- Principal Investigator
  
  Sugimoto Hiroyuki
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Dokkyo Medical University
Identifiadim of new taneraptimsl factors for the enzymes for phospholipid biosynthesis and their impaianoe in cell cyclePrincipal Investigator
- Principal Investigator
  
  SUGIMOTO Hiroyuki
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Dokkyo Medical University
新規生理活性脂質の生体機能
- Principal Investigator
  
  和泉孝志
- Project Period (FY)
  2001 – 2005
- Research Category
  
  Grant-in-Aid for Creative Scientific Research
- Research Institution
  Gunma University
脳ホスホリパーゼDのクローニングと機能解析
- Principal Investigator
  
  山下哲
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Gunma University
新しいホスホリパーゼDのクローニングと新機能の探索
- Principal Investigator
  
  立井一明, 山下哲
- Project Period (FY)
  1998 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (B)
- Review Section
  
  Biological Sciences
- Research Institution
  Gunma University
脳におけるホスホリパーゼDの発現と活性調節
- Principal Investigator
  
  山下哲
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Gunma University
動物組織リゾホスホリパーゼアイソザイムのcDNAクローニングと分化による調節Principal Investigator
- Principal Investigator
  
  杉本博之
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Gunma University
Enzymes and genes involved in phosphatidylcholine signaling
- Principal Investigator
  
  YAMASHITA Satoshi
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional biochemistry
- Research Institution
  Gunma University
動物組織リゾホスオ-リパーゼのcDNAクローニングと細胞内シグナル伝達への関与Principal Investigator
- Principal Investigator
  
  杉本博之
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Gunma University
Phosphatidylcholine metabolism and intracellular signal transduction
- Principal Investigator
  
  YAMASHITA Satoshi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Gunma University
ラット肝臓リゾホスホリパーゼのcDNAクローニングと細胞内シグナル伝達への関与Principal Investigator
- Principal Investigator
  
  杉本博之
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Gunma University
リゾホスホリパーゼ/アシルトランスフェラーゼの精製と細胞内シグナル伝達への関与Principal Investigator
- Principal Investigator
  
  杉本博之
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Gunma University
STIMULATION AND DISORDER OF PHOSPHATIDYLCHOLINE METABOLISM CELL GROWTH
- Principal Investigator
  
  YAMASHITA Satoshi
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Gunma University
yas産物p21によるホスファチジルコリン代謝回転の促進とその分子機構
- Principal Investigator
  
  YAMASHITA Satoshi
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Gunma University

[Journal Article] Autophagy inhibition suppresses hormone production and cell growth in pituitary tumor cells: A potential approach to pituitary tumors2024
- Author(s)
  Satou Motoyasu、Wang Jason、Nakano-Tateno Tae、Teramachi Mariko、Aoki Shigeki、Sugimoto Hiroyuki、Chik Constance、Tateno Toru
- Journal Title
  
  Molecular and Cellular Endocrinology
  
  Volume: 586 Pages: 112196-112196
- DOI
  10.1016/j.mce.2024.112196
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0399, KAKENHI-PROJECT-23K08016, KAKENHI-PROJECT-22K19368
[Journal Article] Transcription of cytochrome P450 46A1 in NIH3T3 cells is negatively regulated by FBS2022
- Author(s)
  Shinohara Y, Ando H, Maekawa M, Arai M, Horibata Y, Satou M, Jojima T, Usui I, Aso Y, Sugimoto H.
- Journal Title
  
  Biochim Biopys Acta Mol Cell Biol Lipids
  
  Volume: 1867(6) Issue: 6 Pages: 159136-159136
- DOI
  10.1016/j.bbalip.2022.159136
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07314, KAKENHI-PROJECT-20K07329, KAKENHI-PROJECT-21K06824, KAKENHI-PROJECT-20K08893
[Journal Article] The zonula occludens protein family regulates the hepatic barrier system in the murine liver2021
- Author(s)
  Masahiko Itoh, Misao Terada, Hiroyuki Sugimoto
- Journal Title
  
  BBA - Molecular Basis of Disease
  
  Volume: 1867(1) Issue: 1 Pages: 165994-165994
- DOI
  10.1016/j.bbadis.2020.165994
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07513, KAKENHI-PROJECT-20K07314, KAKENHI-PROJECT-16H06280
[Journal Article] Locations and contributions of the phosphotransferases EPT1 and CEPT1 to the biosynthesis of ethanolamine phospholipids.2020
- Author(s)
  Horibata Y, Ando H, Sugimoto H.
- Journal Title
  
  Journal of Lipid Research
  
  Volume: 61 Issue: 8 Pages: 1221-1231
- DOI
  10.1194/jlr.ra120000898
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07314, KAKENHI-PROJECT-17K08642
[Journal Article] The phosphatidylcholine transfer protein StarD7 is important for myogenic differentiation in mouse myoblast C2C12 cells and human primary skeletal myoblasts.2020
- Author(s)
  Horibata Y, Mitsuhashi S, Shimizu H, Maejima S, Sakamoto H, Aoyama C, Ando H, Sugimoto H
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 2845-2845
- DOI
  10.1038/s41598-020-59444-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08642, KAKENHI-PROJECT-16H06280, KAKENHI-PROJECT-20K07314
[Journal Article] Imaging of lysophosphatidylcholine in an induced pluripotent stem cell-derived endothelial cell network2020
- Author(s)
  Shimizu Yasuo、Nakamura Yusuke、Horibata Yasuhiro、Fujimaki Mio、Hayashi Keitaro、Uchida Nobuhiko、Morita Hiroko、Arai Ryo、Chibana Kazuyuki、Takemasa Akihiro、Sugimoto Hiroyuki
- Journal Title
  
  Regenerative Therapy
  
  Volume: 14 Pages: 299-305
- DOI
  10.1016/j.reth.2020.03.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08603, KAKENHI-PROJECT-20K07314
[Journal Article] L-type amino acid transporter 1, LAT1, in growth hormone-producing pituitary tumor cells2020
- Author(s)
  Satou Motoyasu、Wang Jason、Nakano-Tateno Tae、Teramachi Mariko、Suzuki Tokiko、Hayashi Keitaro、Lamothe Shawn、Hao Yubin、Kurata Harley、Sugimoto Hiroyuki、Chik Constance、Tateno Toru
- Journal Title
  
  Molecular and Cellular Endocrinology
  
  Volume: 515 Pages: 110868-110868
- DOI
  10.1016/j.mce.2020.110868
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08603, KAKENHI-PROJECT-20K07314
[Journal Article] Effects of the differential expression of ZO-1 and ZO-2 on podocyte structure and function.2018
- Author(s)
  Itoh M, Nakadate K, Matsusaka T, Hunziker W, Sugimoto H
- Journal Title
  
  Genes Cells
  
  Volume: 23 Issue: 7 Pages: 546-556
- DOI
  10.1111/gtc.12598
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08158, KAKENHI-PROJECT-17K08525, KAKENHI-PROJECT-18H02827, KAKENHI-PROJECT-15K08284
[Journal Article] Ethanolamine phosphotransferase 1 (selenoprotein I) is critical for the neural development and maintenance of plasmalogen in human.2018
- Author(s)
  Horibata Y, Elpeleg O, Eran A, Hirabayashi Y, Savitzki D, Tal G, Mandel H, Sugimoto H
- Journal Title
  
  Journal of Lipid Research
  
  Volume: 59 Issue: 6 Pages: 1-12
- DOI
  10.1194/jlr.p081620
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08284, KAKENHI-PROJECT-17K08642
[Journal Article] Changes of plasmalogen phospholipid levels during differentiation of induced pluripotent stem cells 409B2 to endothelial phenotype cells2017
- Author(s)
  Yusuke Nakamura, Yasuo Shimizu, Yasuhiro Horibata, Rinna Tei, Ryosuke Koike1, Meitetsu Masawa, Taiji Watanabe, Taichi Shiobara, Ryo Arai, Kazuyuki Chibana, Akihiro Takemasa, Hiroyuki Sugimoto, Yoshiki Ishii
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 1-9
- DOI
  10.1038/s41598-017-09980-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08284, KAKENHI-PROJECT-16K09553, KAKENHI-PROJECT-17K08642
[Journal Article] Identification of the N-terminal transmembrane domain of StarD7 and its importance for mitochondrial outer membrane localization and phosphatidylcholine transfer.2017
- Author(s)
  Horibata Y, Ando H, Satou M, Shimizu H, Mitsuhashi S, Shimizu Y, Itoh M, Sugimoto H
- Journal Title
  
  Scientific Reports
  
  Volume: 7(1) Issue: 1 Pages: 8793-8793
- DOI
  10.1038/s41598-017-09205-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08158, KAKENHI-PROJECT-15K08284, KAKENHI-PROJECT-17K08642
[Journal Article] The exon 38-containing ARHGEF11 splice isoform is differentially expressed and is required for migration and growth in invasive breast cancer cells2017
- Author(s)
  Itoh Masahiko、Radisky Derek C.、Hashiguchi Masaaki、Sugimoto Hiroyuki
- Journal Title
  
  Oncotarget
  
  Volume: 8 Issue: 54 Pages: 92157-92170
- DOI
  10.18632/oncotarget.20985
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08158, KAKENHI-PROJECT-15K08284
[Journal Article] Matrix-assisted laser desorption/ionization imaging mass spectrometry reveals changes of phospholipid distribution in induced pluripotent stem cell colony differentiation.2017
- Author(s)
  Shimizu Y, Satou M, Hayashi K, Nakamura Y, Fujimaki M, Horibata Y, Ando H, Watanabe T, Shiobara T, Chibana K, Takemasa A, Sugimoto H, Anzai N, Ishii Y.
- Journal Title
  
  Anal Bioanal Chem.
  
  Volume: 291 Issue: 4 Pages: 1007-1016
- DOI
  10.1007/s00216-016-0015-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08284, KAKENHI-PROJECT-16K09553
[Journal Article] StarD7 Protein Deficiency Adversely Affects the Phosphatidylcholine Composition, Respiratory Activity, and Cristae Structure of Mitochondria2016
- Author(s)
  Horibata Y, Ando H, Zhang P, Vergnes L, Aoyama C, Itoh M, Reue K, Sugimoto H
- Journal Title
  
  J Biol Chem.
  
  Volume: 291(48) Issue: 48 Pages: 24880-24891
- DOI
  10.1074/jbc.m116.736793
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08158, KAKENHI-PROJECT-15K08284
[Journal Article] Protein purification and cloning of diacylglycerol lipase from rat brain.2016
- Author(s)
  Aso C, Araki M, Ohshima N, Tatei K, Hirano T, Obinata H, Kishi M, Kishimoto K, Konishi A, Goto F, Sugimoto H, Izumi T.
- Journal Title
  
  J. Biochem.
  
  Volume: 159 Issue: 6 Pages: 585-597
- DOI
  10.1093/jb/mvw002
- NAID
  40020869378
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390069, KAKENHI-PROJECT-25440080, KAKENHI-PROJECT-15K08284
[Journal Article] Mole ghrelin: cDNA cloning, gene expression, and diverse molecular forms in Mogera imaizumii.2016
- Author(s)
  Satou M, Kaiya H, Nishi Y, Shinohara A, Kawada S, Miyazato M, Kangawa K, Sugimoto H.
- Journal Title
  
  Gen Comp Endocrinol
  
  Volume: 232 Pages: 199-210
- DOI
  10.1016/j.ygcen.2016.04.014
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461570, KAKENHI-PROJECT-26440174, KAKENHI-PROJECT-15K15357, KAKENHI-PROJECT-15K08284
[Journal Article] Identification of activated protein C as a ghrelin endopeptidase in bovine plasma.2015
- Author(s)
  Satou M, Nishi Y, Hishinuma A, Hosoda H, Kangawa K, Sugimoto H.
- Journal Title
  
  J Endocrinol.
  
  Volume: 224 Issue: 1 Pages: 61-73
- DOI
  10.1530/joe-14-0529
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590358, KAKENHI-PROJECT-25461570, KAKENHI-PROJECT-26460684
[Journal Article] Transcriptional suppression of CTP:phosphoethanolamine cytidylyltransferase by 25-hydroxycholesterol is mediated by nuclear factor-Y and Yin Yang 12015
- Author(s)
  Ando H, Aoyama C, Horibata Y, Satou M, Mitsuhashi S, Itoh M, Hosaka K, Sugimoto H
- Journal Title
  
  Biochemical Journal
  
  Volume: 471 Issue: 3 Pages: 369-379
- DOI
  10.1042/bj20150318
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08158, KAKENHI-PROJECT-15K08284, KAKENHI-PROJECT-23590242, KAKENHI-PROJECT-24590358, KAKENHI-PROJECT-25870668
[Journal Article] The Structural and Functional Organization of the Podocyte Filtration Slits Is Regulated by Tjp1/ZO-1.2014
- Author(s)
  Itoh M, Nakadate K, Horibata Y, Matsusaka T, Xu J, Hunziker W, Sugimoto H.
- Journal Title
  
  PLoS One.
  
  Volume: 9・9 Issue: 9 Pages: e106621-e106621
- DOI
  10.1371/journal.pone.0106621
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-22249033, KAKENHI-PROJECT-23590242, KAKENHI-PROJECT-24590358, KAKENHI-PROJECT-25870668, KAKENHI-PROJECT-26460283
[Journal Article] Muscular dystrophy with large mitochondria associated with mutations in the CHKB gene in three British patients: Extending the clinical and pathological phenotype2013
- Author(s)
  Ros Quinlivan, Satomi Mitsuahashi, Caroline Sewry, Sebahattin Cirak, Chieko Aoyama, David Mooore, Stephen Abbs, Stephanie Robb, Tina Newton, Celia Moss, Daniel Birchall, Hiroyuki Sugimoto, Kate Bushby, Michela Guglieri, Francesco Muntoni, Ichizo Nishino, Volker Straub
- Journal Title
  
  Neuromusucular Disorders
  
  Volume: 23 Issue: 7 Pages: 549-556
- DOI
  10.1016/j.nmd.2013.04.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590358
[Journal Article] Cysteine mutations cause defective tyrosine phosphorylation in MEGF10 myopathy2013
- Author(s)
  Satomi Mitsuhashi, Hiroaki Mitsuhashi, Matthew S. Alexander, Hiroyuki Sugimoto, Peter B. Kang
- Journal Title
  
  FEBS Letters
  
  Volume: 587 Issue: 18 Pages: 2952-2957
- DOI
  10.1016/j.febslet.2013.08.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590358
[Journal Article] Enzymatic and transcriptional regulation of the cytoplasmic acetyl-CoA hydrolase ACOT122013
- Author(s)
  Horibata Y, Ando H, Itoh M, Sugimoto H.
- Journal Title
  
  Journal of Lipid Research
  
  Volume: 54(8) Issue: 8 Pages: 2049-2059
- DOI
  10.1194/jlr.m030163
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590242, KAKENHI-PROJECT-24590358, KAKENHI-PROJECT-25870668
[Journal Article] Rho GTP exchange factor ARHGEF11 regulates the integrity of epithelial junctions by connecting ZO-1 and RhoA-myosin II signaling2012
- Author(s)
  Itoh, M., Tsukita, S., Yamazaki, Y., and Sugimoto, H.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 109 Issue: 25 Pages: 9905-9910
- DOI
  10.1073/pnas.1115063109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0313, KAKENHI-PUBLICLY-23114507, KAKENHI-PROJECT-23590242, KAKENHI-PROJECT-23659172, KAKENHI-PLANNED-24113002, KAKENHI-PROJECT-24247037, KAKENHI-PROJECT-24590358
[Journal Article] The study of ghrelin deacylation enzymes2012
- Author(s)
  Satou M, Sugimoto, H.
- Journal Title
  
  Methods Enzymol
  
  Volume: 514 Pages: 165-179
- DOI
  10.1016/b978-0-12-381272-8.00011-8
- ISBN
  9780123812728
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21770149, KAKENHI-PROJECT-24590358
[Journal Article] Transcriptional regulation of phosphatidylcholine biosynthesis2008
- Author(s)
  Sugimoto H, Banchio C, Vance DE
- Journal Title
  
  Progress in Lipid Research 47
  
  Pages: 204-220
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590265
[Journal Article] Transcriptional regulation of phosphatidylcholine biosynthesis2008
- Author(s)
  Sugimoto, H., Banchio C, Vance, DE
- Journal Title
  
  Progress in Lipid Research 47
  
  Pages: 204-220
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590265
[Journal Article] Induction of choline kinase alpha by carbon tetrachloride(CCl_4) occurs via increased binding of cjun to an AP-1 element2007
- Author(s)
  Aoyama C, Iahidate K, Sugimoto H, Vance, DE
- Journal Title
  
  Biochimica et Biophysics Acta 1771
  
  Pages: 1148-1155
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590265
[Journal Article] リン脂質生合成におけるCTP:ホスホコリンシチジリルトランスフェラーゼαの転写制御2007
- Author(s)
  杉本博之
- Journal Title
  
  生化学 79
  
  Pages: 968-972
- NAID
  10019771960
- Data Source
  KAKENHI-PROJECT-17590265
[Journal Article] Indnction of choline kinass alpha by carbon tetrachloride(CCl_4)occurs via increased binding of c-jun to an AP-1 element2007
- Author(s)
  Aoyama C, Ishidate K, Sugimoto H, Vance DE.
- Journal Title
  
  Biochimica et Biophysica Acta 1771
  
  Pages: 1148-1155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590265
[Journal Article] Purification and characterization of Lysopholipase D from rat brain2006
- Author(s)
  Sayaka Sugimoto, Hiroyuki Sugimoto, Chieko Aoyama, Chizu Aso, Masatomo Mori, Takasaki Izumi
- Journal Title
  
  Biochimica et Biophysica Acta 1761
  
  Pages: 1410-1418
- Data Source
  KAKENHI-PROJECT-17590265
[Journal Article] Purification and characterization of lysophospholipase D from rat brain2006
- Author(s)
  Sugimoto S, Sugimoto H, Aoyama C, Aso C, Mon M, Izumi, T
- Journal Title
  
  Biochimica at Biophysics Acta 1761
  
  Pages: 1410-1418
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590265
[Journal Article] Purification and characterization of lysophospholipase D from rat bra2006
- Author(s)
  Sugimoto S, Sugimoto H, Aoyama C, Aso C, Mori M, Izumi T
- Journal Title
  
  Biochimica et Biophysics Acts 1761
  
  Pages: 1410-1418
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590265
[Journal Article] Sp1 is a co-activator with Ets-1, and Net is an important repressor of the transcription of CTP : phosphocholine cytidylyltransferase α2005
- Author(s)
  Hiroyuki Sugimoto, Koichi Okamura, Sayaka Sugimoto, Motoyasu Satou, Tomoyasu Hattori, Dennis E.Vance, Takashi Izumi
- Journal Title
  
  The Journal of Biological Chemistry 280
  
  Pages: 40857-40866
- Data Source
  KAKENHI-PROJECT-17590265
[Journal Article] Sp1 is a co-activator with Ets-1, and Net is an important repressor of the transcription of CTP : photocholine cytidylyltransferase alpha2005
- Author(s)
  Sugimoto, H., et al.
- Journal Title
  
  J Biol Chem. 280・49
  
  Pages: 40857-40866
- Data Source
  KAKENHI-PROJECT-13GS0012
[Journal Article] Spl is a co-activator with Ets-1, and Net is an important repressor of the transcription of CTP : phosphocholine cytidylyltransferaseα2005
- Author(s)
  Sugimoto H, Okamura K, Sugimoto S, Satan M, Hattori T, Vance, DE, Izumi, T
- Journal Title
  
  The Journal of Biological Chemistry 280
  
  Pages: 40857-40866
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590265
[Journal Article] Sp1 is a co-activator with Ets-1,and Net is an important repressor of the transcription of GTP:phosphocholine cytidylyltransferase α2005
- Author(s)
  Sugimoto E, Okamura K, Sugimoto S, Satou M, Hattori T, Vance DE, Izumi T
- Journal Title
  
  The Journal of Biological Chemistry 280
  
  Pages: 40857-40866
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590265
[Presentation] リン脂質・コレステロールのオキシステロールによる合成制御に関与する転写因子とその機構解析2021
- Author(s)
  安戸博美、堀端康博、杉本博之
- Organizer
  分子生物学会
- Data Source
  KAKENHI-PROJECT-20K07314
[Presentation] リン脂質輸送タンパク質StarD7がミトコンドリアにおいて果たす役割2020
- Author(s)
  堀端康博、杉本博之
- Organizer
  脂質生化学会
- Data Source
  KAKENHI-PROJECT-20K07314
[Presentation] オキシステロール産生酵素(コレステロール25-ヒドロキシラーゼ)のインスリン様成長因子による転写制御2020
- Author(s)
  篠原安武1,2、安戸博美1、堀端康博1、前川正充3、杉本博之1
- Organizer
  脂質生化学会
- Data Source
  KAKENHI-PROJECT-20K07314
[Presentation] 細胞膜リン脂質・コレステロールのオキシステロールによる合成制御機構2020
- Author(s)
  安戸博美、堀端康博、杉本博之
- Organizer
  生化学会
- Data Source
  KAKENHI-PROJECT-20K07314
[Presentation] プラズマローゲンの保持におけるEPT1の役割とその変異による脳変性疾患2018
- Author(s)
  堀端康博、Orly Elpeleg、平林義雄、Hanna Mandel、杉本博之
- Organizer
  日本生化学会
- Data Source
  KAKENHI-PROJECT-15K08284
[Presentation] EPT1はエタノールアミンプラズマローゲンの産生と維持に主要な役割を担い、脳神経系の正常な発達を司る2018
- Author(s)
  堀端康博、Orly Elpeleg、平林義雄、Hanna Mandel、杉本博之
- Organizer
  日本脂質生化学会
- Data Source
  KAKENHI-PROJECT-15K08284
[Presentation] オキシステロールによるホスファチジルエタノールアミンおよびコレステロール合成の制御に関与する転写因子の同定と機構解析2018
- Author(s)
  安戸博美、堀端康博、青山智英子、杉本博之
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-15K08284
[Presentation] StarD7が有する膜貫通領域の同定とミトコンドリア局在およびPC輸送における役割2017
- Author(s)
  堀端康博、安戸博美、青山智英子、佐藤元康、清水泰生、伊藤雅彦、杉本博之
- Organizer
  脂質生化学会
- Data Source
  KAKENHI-PROJECT-15K08284
[Presentation] Regulation of cellular oxysterol-producing enzymes by a novel serum-derived factor2017
- Author(s)
  Hiroyuki Sugimoto
- Organizer
  BRIDGING DISCOVERY RESEARCH with THERAPIES
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08284
[Presentation] 25-hydroxycholesterol suppress the transcription of CTP:phosphoethanolamine cytidylyltransferase and HMG-CoA reductase by inhibiting interaction of p300 and NF-Y and H3K27 acetylation2017
- Author(s)
  Hiromi Ando, Chieko Aoyama, Yasuhiro Horibata, Hiroyuki Sugimoto
- Organizer
  BRIDGING DISCOVERY RESEARCH with THERAPIES
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08284
[Presentation] The analysis of cellular lysophospholipase D and interacting molecules2017
- Author(s)
  Chieko Aoyama, Hiromi Ando, Satoko Yamashita, Maki Arai, Hiroyuki Sugimoto
- Organizer
  BRIDGING DISCOVERY RESEARCH with THERAPIES
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08284
[Presentation] StarD7によるミトコンドリアのホスファチジルコリン組成および機能と形態形成の維持2016
- Author(s)
  堀端康博、伊藤雅彦、Peixiang Zhang、Laurent Vergnes、安戸博美、青山智英子、Karen Reue、杉本博之
- Organizer
  日本脂質生化学会
- Place of Presentation
  にぎわい交流会交流会AU(秋田県秋田市)
- Year and Date
  2016-06-09
- Data Source
  KAKENHI-PROJECT-15K08284
[Presentation] オキシステロールによるホスファチジルエタノールアミンおよびコレステロール合成の制御に関与する新規転写因子の同定と機能解析2016
- Author(s)
  安戸博美、青山智英子、堀端康博、佐藤元康、伊藤雅彦、杉本博之
- Organizer
  日本脂質生化学会
- Place of Presentation
  にぎわい交流会交流会AU(秋田県秋田市)
- Year and Date
  2016-06-09
- Data Source
  KAKENHI-PROJECT-15K08284
[Presentation] Oxysterol delivertives and transcriptional factors regulating phosphatidylethanolamine and cholesterol biosynthesis2015
- Author(s)
  Hiromi Ando, Chieko Aoyama, Yasuhiro Horibata, Motoyasu Satou, Masahiko Itoh, Hiroyuki Sugimoto
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会大会・合同会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-24590358
[Presentation] The analysis of intracellular lysophospholipase D consist of Galphaq-Gbete complex and other interacting molecules2015
- Author(s)
  Chieko Aoyama, Hiromi Ando, Satoko Yamashita, Hiroyuki Sugimoto
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会大会・合同会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K08284
[Presentation] The analysis of intracellular lysophospholipase D consist of Galphaq-Gbete complex and other interacting molecules2015
- Author(s)
  Chieko Aoyama, Hiromi Ando, Satoko Yamashita, Hiroyuki Sugimoto
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会大会・合同会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-24590358
[Presentation] Oxysterol delivertives and transcriptional factors regulating phosphatidylethanolamine and cholesterol biosynthesis2015
- Author(s)
  Hiromi Ando, Chieko Aoyama, Yasuhiro Horibata, Motoyasu Satou, Masahiko Itoh, Hiroyuki Sugimoto
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会大会・合同会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K08284
[Presentation] マウス筋芽細胞株におけるコリンキナーゼの発現2014
- Author(s)
  青山智英子、杉本博之
- Organizer
  日本薬学会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24590358
[Presentation] ホスファチジルエタノールアミン合成を制御するオキシステロール代謝産物と転写因子の同定2013
- Author(s)
  安戸博美、青山智英子、山下智子、堀端康博、佐藤元康、三橋里美、杉本博之
- Organizer
  第86回　日本生化学会大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24590358
[Presentation] 脂質生合成を制御する細胞質アセチルCoA分解酵素Acyl-CoAチオエステラーゼ12(ACOT12)の活性調節機構の解析2013
- Author(s)
  堀端康博、安戸博美、伊藤雅彦、杉本博之
- Organizer
  第86回　日本生化学会大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24590358
[Presentation] 活性化プロテインCによる短縮型グレリンの生成とその生理活性2013
- Author(s)
  佐藤元康、杉本博之、西芳寛
- Organizer
  第86回　日本生化学会大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24590358
[Presentation] 細胞内リゾホスホリパーゼDの活性調節2013
- Author(s)
  青山智恵子、山下智子、安戸博美、杉本博之
- Organizer
  日本薬学会　第１３３年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24590358
[Presentation] 細胞内型リゾホスホリパーゼDの局在が活性に及ぼす影響2013
- Author(s)
  青山智英子、三橋里美、安戸博美、山下智子、杉本博之
- Organizer
  第86回　日本生化学会大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24590358
[Presentation] Ets2の核内(NLS)および核外移行シグナル(NES)の同定およびRAW264細胞を用いたM-CSF刺激によるCTP:phosphocholine cytidylytransferaseα(CTα)転写促進におけるEts2の重要性2007
- Author(s)
  岡邨興一、山下智子、堀端康弘、高岸憲二、Dermis E Vance、和泉孝志、杉本博之
- Organizer
  BMB2007(第30回日本分子生物学会年会・第80回日本化学大会合同大会)
- Place of Presentation
  横浜
- Year and Date
  2007-12-12
- Data Source
  KAKENHI-PROJECT-17590265
[Presentation] Ets2の核按内(NLS)および核外移行シグナル(NES)の同定およびRAW264細胞を用いた階刺激によるCTP:phosphocholine cytidylyltransferase a(CTα)転写促進におけるEts2の重要性2007
- Author(s)
  岡郁興一、山下智子、堀端康弘、高岸憲二、Dennis E Vence、和泉孝志、杉本博之
- Organizer
  BMB2007(第30回日本分子生物学会年会、第80回日本生化学会大会合同大会)
- Place of Presentation
  横浜
- Year and Date
  2007-12-12
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590265
[Presentation] Identification of NLS and NES in Ets2 and the transcriptional regulation of Ets2 and CTP : phosphocholine cytidylyltransferase a ; in M-CSF stimulated RAW293 cells2007
- Author(s)
  Okamura S, Yamashita S, Horibata, Takagiahi K, Vance, DE, Izumi T, Sugimoto, H
- Organizer
  BMB2007
- Place of Presentation
  Yokohama
- Year and Date
  2007-12-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590265
[Presentation] cDNA cloning of ghrelin gene and its gene regulation in Mogera Imaizumii
- Author(s)
  Satou M, Nishi Y, Kawata S, Shinohara A, Chiba T, Sugimoto H.
- Organizer
  分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-24590358
[Presentation] Transcriptional suppression of CTP:phosphoethanolamine cytidylyltransferase and HMG-CoA reductase by 25-hydroxycholesterol is mediated by nuclear factor-Y and Yin Yang1.
- Author(s)
  Ando H, Aoyama C, Horibata Y, Sugimoto H.
- Organizer
  Deuel Conference on Lipids
- Place of Presentation
  Monterey, California
- Year and Date
  2015-03-03 – 2015-03-06
- Data Source
  KAKENHI-PROJECT-24590358
[Presentation] Regulatory systems of acyl-CoA thioesterase 12 (ACOT12) that control cytosolic acetyl-CoA degradation and the lipid biosynthesis.
- Author(s)
  Horibata Y, Ando H, Itoh M, Sugimoto H.
- Organizer
  Deuel Conference on Lipids
- Place of Presentation
  Monterey, California
- Year and Date
  2015-03-03 – 2015-03-06
- Data Source
  KAKENHI-PROJECT-24590358
[Presentation] ホスファチジルエタノールアミン、コレステロールの合成制御におけるオキシステロール代謝産物と新規転写因子の役割
- Author(s)
  安戸博美、青山智英子、保坂公平、杉本博之
- Organizer
  日本脂質生化学会
- Place of Presentation
  大阪
- Year and Date
  2014-06-06 – 2014-06-07
- Data Source
  KAKENHI-PROJECT-24590358
[Presentation] The heterotrimeric G protein subunits Gαq and Gβ1 have lysophospholipase D activity.
- Author(s)
  Aoyama C, Ando H, Sugimoto H.
- Organizer
  Deuel Conference on Lipids
- Place of Presentation
  Monterey, California
- Year and Date
  2015-03-03 – 2015-03-06
- Data Source
  KAKENHI-PROJECT-24590358

1. YAMASHITA Satoshi (50025623)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
2. OKAMURA Shinichi (20224058)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. TATEI Kazuaki (00192633)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
4. SATOU Motoyasu (20418891)

# of Collaborated Projects: 3 results

# of Collaborated Products: 13 results
5. ANDO Hiromi (10704885)

# of Collaborated Projects: 3 results

# of Collaborated Products: 24 results
6. UCHIDA Tsutomu (00160276)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. HOSAKA Kohei (70108992)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. SONE Michio (00302464)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. AOYAMA Chieko (90420778)

# of Collaborated Projects: 2 results

# of Collaborated Products: 18 results
10. HORIBATA Yasuhiro (80392116)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
11. KODAKI Tsutomu (70170264)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 和泉孝志 (70232361)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. 新井洋由 (40167987)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 青木淳賢 (20250219)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 小橋元 (60270782)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 出沢真理 (50272323)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 春山康夫 (20406185)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 麻生好正 (80212512)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 内山浩志 (00711318)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 高山英士 (50958311)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. OHSHIMA Noriyasu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. HAYASHI Keitaro

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
23. YAMAZAKI Yuji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 伊藤雅彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 7 results
25. 松阪泰二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 岸本幸治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 青木重樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 月田早智子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 西芳寛

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

sugimoto hiroyuki 杉本 博之

杉本 博之 スギモト ヒロユキ

Sugimoto Hiroyuki 杉本 博之

SUGIMOTO Hiroyuki 杉本 博之

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インスリン様成長因子等による側鎖型オキシステロール産生調節を介した新規情報伝達Principal Investigator

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Identification of regulation factor for oxysterol production in FBS and its nobel signal transductionPrincipal Investigator

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Identification of novel transcriptional factors and their roles for homeostasis of lipid composition of cell membranePrincipal Investigator

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Identifiadim of new taneraptimsl factors for the enzymes for phospholipid biosynthesis and their impaianoe in cell cyclePrincipal Investigator

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動物組織リゾホスホリパーゼアイソザイムのcDNAクローニングと分化による調節Principal Investigator

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動物組織リゾホスオ-リパーゼのcDNAクローニングと細胞内シグナル伝達への関与Principal Investigator

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sugimoto hiroyuki 杉本博之

杉本博之スギモトヒロユキ

Sugimoto Hiroyuki 杉本博之

SUGIMOTO Hiroyuki 杉本博之