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MURAKAMI Masahiro  村上 正洋

ORCIDConnect your ORCID iD *help
Researcher Number 00239500
Other IDs
Affiliation (based on the past Project Information) *help 2007 – 2016: 日本医科大学, 医学部, 准教授
2005 – 2006: Nippon medical School, Medicine, Associate Professor, 医学部, 助教授
2004: 日本医科大学, 医学部, 助手
2002 – 2004: 日本医科大学, 医学部, 講師
2000 – 2002: 日本医科大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Plastic surgery
Except Principal Investigator
Plastic surgery / Plastic surgery
Keywords
Principal Investigator
tissue engineering / cartilage / stem cells / regenerative medicine / 脂肪組織 / 脂肪 / 間葉系幹細胞 / 組織工学 / 軟骨 / 幹細胞 … More / 再生医学 / IL-17 / Treg / Treg / Th17 / 制御性T細胞 / IL-17 / ケロイド … More
Except Principal Investigator
ケロイド / DNA-MICROARRAY / β-catenin / 分子標的治療 / 組織工学 / 再生医学 / 脂肪 / 間葉系幹細胞 / EXTRACELLULAR MATRIX / REAL-TIME PCR / HYPERTROPHIC SCARS / KELOIDS / 細胞増殖 / SNP / 肥厚性瘢痕 / keloid / 皮膚 / 線維芽細胞 / 遺伝子解析 / 培養線維芽細胞 / 培養細胞 / tissue engineering / regenerative medicine / skin / adipose tissue / mesenchymal stem cells / axin / Wnt signal / fibloblasts / β-caternin / Axin / Wntシグナル / Tissue Engineering / Regenerative Medicine / Fat / Mesenchymal stem cells / 脂肪組織 / PROTEOGALYCANS / PAR-1 / II-24 / マイクロビーズ・アレイ / Decorin / TGF-β1 / Mda-7 / Par-1 / c-erb B / Real-Time PCR / promoter領域 / collagen形成 / microarray解析 / decorin / lumican / ケロイド培養線維芽細胞 / PROTEOGLYCANS / PATHOLOGICAL GENOMICS / TUMOR SUPPRESSORS / HYPERTROPHIC SCAR / KELOID / apoptosis / PCR / NMR / 遺伝子多型性 / p53遺伝子 / Pathological Genomics / 分子病態 / 腫瘍抑制遺伝子 / DNA-microarray / frizzled4 / ROR2 / frizzeld4 / wound healing / keloid pathogenesis / Wnt signaling / Wnt signal-related genes / EMT / beta-catenin / Wnt5a / Keloid pathogenesis / Th17 / ケロイドモデル / IL-23 / IL-17 / 新しい分子治療 / c-Ab1 / 皮膚線維芽細胞 / c-Abl / IL-6受容体 / STAT3 / IL-6シグナル / IL-6 / 創傷治癒学 Less
  • Research Projects

    (11 results)
  • Research Products

    (9 results)
  • Co-Researchers

    (16 People)
  •  Elucidation of immune response by Th17/Treg in keloid and application of new therapyPrincipal Investigator

    • Principal Investigator
      MURAKAMI MASAHIRO
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Plastic surgery
    • Research Institution
      Nippon Medical School
  •  Elucidation of Wnt5a signal transduction mechanism(s) in keloid and application of molecular targeted therapy

    • Principal Investigator
      GHAZIZADEH MOHAMMAD
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Plastic surgery
    • Research Institution
      Nippon Medical School
  •  Establishment of new molecular therapy of keloid and elucidation of mechanism of development by inhibition of cAbl tyrosine kinase

    • Principal Investigator
      GHAZIZADEH M. (GHAZIZADEH MOHAMMAD Ghazizadeh)
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Plastic surgery
    • Research Institution
      Nippon Medical School
  •  Establishment of new molecular therapy of keloid and elucidation of mechanism of development by IL-23/IL-17 pathway

    • Principal Investigator
      TOSA Mamiko
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Plastic surgery
    • Research Institution
      Nippon Medical School
  •  Establishment of novel molecular target therapy and determination of developmental mechanism of keloid by inhibition of IL-6 signaling

    • Principal Investigator
      TOSA Mamiko
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Plastic surgery
    • Research Institution
      Nippon Medical School
  •  Therapeutic approach for refractory skin ulcers by adipose derived stem cells

    • Principal Investigator
      IWAKIRI Itaru
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Plastic surgery
    • Research Institution
      Nippon Medical School
  •  Molecular biological analysis of the Wnt signal pathway in keloid development

    • Principal Investigator
      TOSA Mamiko
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Plastic surgery
    • Research Institution
      Nippon Medical School
  •  In vivo 3 dimensional cartilage tissue engineering by adipose derived stem cellsPrincipal Investigator

    • Principal Investigator
      MURAKAMI Masahiro
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Plastic surgery
    • Research Institution
      Nippon Medical School
  •  Genomics Study on Keloids and Hypertrophic Scars

    • Principal Investigator
      HYAKUSOKU Hiko
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Plastic surgery
    • Research Institution
      Nippon Medical School
  •  3 dimensional fat regeneration using Adipose derived stem cells

    • Principal Investigator
      MIZUNO Hiroshi
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Plastic surgery
    • Research Institution
      Nippon Medical School
  •  Genomic Study on Keloids and Hypertrophic Scars

    • Principal Investigator
      HYAKUSOKU Hiko
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Plastic surgery
    • Research Institution
      NIPPON MEDICAL SCHOOL

All 2013 2011 2010 2009 2007 2006

All Journal Article Presentation

  • [Journal Article] Identification and characterization of Wnt signaling pathway in keloid pathogenesis2013

    • Author(s)
      Shinichi Igota, Mamiko Tosa, Masahiro Murakami, Seiko Egawa, Hajime Shimizu, Hiko Hyakusoku, Mohammad Ghazizadeh
    • Journal Title

      International Journal of Medical Sciences

      Volume: 10 Issue: 4 Pages: 344-354

    • DOI

      10.7150/ijms.5349

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24592722
  • [Journal Article] Chronologic change of the maximum dimension of BCG-induced keloids2009

    • Author(s)
      Tosa M, Murakami M, Ghazizadeh M, Hyakusoku H.
    • Journal Title

      Dermatol Surg

      Volume: 35(2) Issue: 2 Pages: 189-194

    • DOI

      10.1111/j.1524-4725.2008.34408.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592297
  • [Presentation] Involvement of Wnt signaling pathway in keloid pathogenesis2011

    • Author(s)
      伊吾田慎一、土佐眞美子、清水一、村上正洋、ガジザデモハマッド
    • Organizer
      第20回日本形成外科学会基礎学術集会
    • Place of Presentation
      東京
    • Year and Date
      2011-10-07
    • Data Source
      KAKENHI-PROJECT-21592297
  • [Presentation] ケロイドにおけるTh17細胞のIL-6シグナル促進効果の検討2011

    • Author(s)
      土佐眞美子、ガジザデ・モハマッド、村上正洋、百束比古
    • Organizer
      第20回日本形成外科基礎学術集会
    • Place of Presentation
      新宿
    • Year and Date
      2011-10-06
    • Data Source
      KAKENHI-PROJECT-21592298
  • [Presentation] 炎症的側面と腫瘍的側面を持つケロイドに対する基礎的アプローチ2010

    • Author(s)
      土佐眞美子、ガジザデ・モハマッド、村上正洋、百束比古
    • Organizer
      第19回日本形成外科基礎学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2010-09-16
    • Data Source
      KAKENHI-PROJECT-21592298
  • [Presentation] Effect of imatinib mesylate(STI571) on keloid fibroblast cell functions2009

    • Author(s)
      Ghazizadeh M, Shimizu H, Tosa M, Egawa Seiko, Murakami M
    • Organizer
      The 34th Annual Meeting of the Japanese Society for Investigative Dermatology
    • Place of Presentation
      Fukuoka
    • Data Source
      KAKENHI-PROJECT-21592297
  • [Presentation] ケロイド患者におけるヘルパーT細胞サブタイプの解析2009

    • Author(s)
      土佐眞美子、ガジザデ・モハマッド、村上正洋、百束比古
    • Organizer
      第18回日本形成外科基礎学術集会
    • Place of Presentation
      東京
    • Year and Date
      2009-10-01
    • Data Source
      KAKENHI-PROJECT-21592298
  • [Presentation] ケロイドに対する新治療薬としてのヒト化抗ヒトIL-6受容体抗体の臨床応用を目指した基礎研究2007

    • Author(s)
      土佐眞美子、ガジザデ・モハマッド、村上正洋、百束比古
    • Organizer
      第16回日本形成外科基礎学術集会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-18591973
  • [Presentation] 抗IL-6受容体抗体によるケロイド由来線維芽細胞の増殖抑制効果の検討2006

    • Author(s)
      土佐眞美子、ガジザデ・モハマッド、村上正洋、百束比古
    • Organizer
      第15回日本形成外科基礎学術集会
    • Place of Presentation
      大宮
    • Data Source
      KAKENHI-PROJECT-18591973
  • 1.  TOSA Mamiko (30301568)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 9 results
  • 2.  MOHAMMAD Ghazizadeh (30190979)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 3.  HYAKUSOKU Hiko (00165135)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 4.  SHIMIZU Hajime (60398873)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 3 results
  • 5.  MIZUNO Hiroshi (80343606)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  KAWANAMI Ouichi (70096973)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  NAKAZAWA Nando (20010051)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  AKAISHI Satoshi (10373010)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  MINAMI SHIROU (10192361)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  IGOTA Shinichi (30339361)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  IWAKIRI Itaru (50307899)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  金 恩京 (10312068)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  石丸 さやか (00297889)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  平井 隆 (40208799)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  河原 理子 (30328794)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  ガジザデ モハマッド
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 9 results

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