tsuchiya ken 土谷健

… Alternative Names

TSUCHIYA Ken 土谷健

土屋健ツチヤケン

土谷健ツチヤケン

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Researcher Number	00246472
Other IDs
Affiliation (Current)	2025: 東京女子医科大学, 医学部, 特任教授
Affiliation (based on the past Project Information) *help	2016 – 2019: 東京女子医科大学, 医学部, 教授 2015: 東京女子医科大学, 医学部, 准教授 2014: 東京女子医科大学, 医学部, 臨床教授 2007 – 2013: Tokyo Women's Medical University, School of Medicine, Associate Professor 2006: 東京女子医科大学, 医学部, 助教授 … More 1999 – 2005: Tokyo Women's Medical University, Dept.of Med. Assosiate Professor, 医学部, 講師 1997 – 1998: 東京女子医科大学, 医学部, 助手 1994 – 1995: 東京女子医科大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Kidney internal medicine / Kidney internal medicine Except Principal Investigator Digestive surgery / Digestive surgery / Pediatrics / Kidney internal medicine
Keywords	Principal Investigator 慢性腎臓病 / Klotho / リン / CKD / 嚢胞腎 / ノックアウトマウス / 左右軸 / microarray / RNAi / knockout mouse … More / のう胞腎 / 内臓逆位 / アンキリン / AKI / 線維化 / FGF23 / 繊維化 / klotho / マイクロアレイ / 繊毛 / 虚血 / 急性腎障害 / cilia / left-right asymmetry / polycystic kidney / 体軸 / 内蔵逆位 / RNA i / 発生分化 / 遺伝子 / Cystic kidney / Situs inversus / left-right axis / モノクローナル抗体 / 左右決定 / Ankyrin / Transgenic mouse / Polystic kidney / K ATPase / Na / NalkATPase / モノクロナル抗体 / トランスジェニックマウス / Phosphate / futuin A / fetuin A / 老化 / トランスレーションリサーチ / 長寿命化 / 生理活性 / ESA / 培養細胞 / アデノウィルス / inv遺伝子 / siRNA … More Except Principal Investigator c-maf / transcription factor / mafA / siRNA / maf / 転写因子 / インスリン / mafB / 膵細胞 / porcine / Insulin / βcell / maf B / maf A / insulin / islet / ブタ / adinocytokine / adipocyte / β cell / pancreatic cell / β細胞 / 発生分化 / adipocytokine / 脂肪細胞 / グルコース反応性 / 膵β細胞 / Glucose Response / PDX-1 / pancreatis β cell / ラ氏島 / GLP-1 / cDNA array / FSGS factors / podocyte / proteinuria / primary FSGS / CDNAアレイ / 液性因子 / cDNAアレイ / 蛋白尿惹起液性因子 / ポドサイト / 蛋白尿 / 原発性FSGS / G-protein / peptide / pertussis toxin / extracellular matrix / TGF-beta / Fibroblast / フィブロネクチン / G蛋白 / TGF-β受容体 / ペプチド / 百日咳毒素 / 細胞外基質 / TGF-β / 線維芽細胞 / 糖尿病 / 細胞極性 / large maf / microarray / microarry / マイクロアレイ / インシュリン / 人工膵島 Less

Elucidation and therapeutic intervention of the mechanism of CKD onset and aggravation due to repeated and accumulated mild renal damagesPrincipal Investigator
- Principal Investigator
  
  Tsuchiya Ken
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Tokyo Women's Medical University
Significance of Klotho as a target molecule for CKD progression, severe process and early interventionPrincipal Investigator
- Principal Investigator
  
  TSUCHIYA KEN
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Tokyo Women's Medical University
Treating strategie for CKD with Klotho as a targetting moleculePrincipal Investigator
- Principal Investigator
  
  TSUCHIYA KEN
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Tokyo Women's Medical University
Functional analysis of glucose related transcriptional factors using direct RNA sequence and mechanosensor
- Principal Investigator
  
  TSUCHIYA MARIKO
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Tokyo Women's Medical University
Reserch of large maf transcription factors on pancreatic cell and preadipocyte differentiation
- Principal Investigator
  
  TSUCHIYA Mariko
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Tokyo Women's Medical University
Making conditional knockout mouse of the gene coding inversin and the significance of inversion in the cilia-dependent renal diseasePrincipal Investigator
- Principal Investigator
  
  TSUCHIYA Ken
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Tokyo Women's Medical University
Study on pancreatic cell lineage of growth and differentiation in culture cells and tissue
- Principal Investigator
  
  TSUCHIYA Mariko
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Tokyo Women's Medical University
Production of inv (Inversion of embryonic turning) gene knockout mouse and development of disease related animal modelsPrincipal Investigator
- Principal Investigator
  
  TSUCHIYA Ken
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Tokyo Women's Medical University
Analysis by cDNA array of altered gene expression in mouse cultured podocytes in response to plasma from recurrent-focal segmental glomerulosclerosis patients
- Principal Investigator
  
  HATTORI Motoshi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Tokyo Women's Medical University
Development of pancreatic stem cell and β-cell for cell therapy
- Principal Investigator
  
  TSUCHIYA Mariko
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Tokyo Women's Medical University
Functional analisis of invgene which determines lef-right axis and relates to renal developmentPrincipal Investigator
- Principal Investigator
  
  TSUCHIYA Ken
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Tokyo Woman's Medical University
膵幹細胞のβ細胞への分化増殖に関する転写因子の検討とハイブリッド型人工膵の開発
- Principal Investigator
  
  TSUCHIYA Mariko
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Tokyo Women's Medical University
Molecular analysis of cystic kidney formed transgenic mouse generated by insertional mutationPrincipal Investigator
- Principal Investigator
  
  TSUCHIYA Ken
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Tokyo Women's Medical University
Involvement of G-protein in the TGF-beta-induced extracellular matrix synthesis
- Principal Investigator
  
  NIHEI Hiroshi
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Tokyo Women's Medical College

[Journal Article] High Serum Phosphate Level as a Risk Factor to Determine Renal Prognosis in Autosomal Dominant Polycystic Kidney Disease: A Retrospective Study.2020
- Author(s)
  Sato M, Kataoka H, Ushio Y, Manabe S, Watanabe S, Akihisa T, Makabe S, Yoshida R, Iwasa N, Mitobe M, Hanafusa N, Tsuchiya K, Nitta K, Mochizuki T.
- Journal Title
  
  Medicines (Basel).
  
  Volume: 7 Issue: 3 Pages: 13-13
- DOI
  10.3390/medicines7030013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09714
[Journal Article] The Importance of Biologically Active Vitamin D for Mineralization by Osteocytes After Parathyroidectomy for Renal Hyperparathyroidism.2019
- Author(s)
  Yajima A, Tsuchiya K, Burr DB, Wallace JM, Damrath JD, Inaba M, Tominaga Y, Satoh S, Nakayama T, Tanizawa T, Ogawa H, Ito A, Nitta K.
- Journal Title
  
  JBMR Plus.
  
  Volume: 3 Issue: 11
- DOI
  10.1002/jbm4.10234
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09714
[Journal Article] Strategies for the Super-Aged Dialysis Population: Survival Benefits or Alternative Goals?2019
- Author(s)
  Sakurai S, Hanafusa N, Nomura T, Tsuchiya K, Nitta K, Nangaku M.
- Journal Title
  
  Blood Purif.
  
  Volume: 47 Issue: Suppl. 2 Pages: 95-105
- DOI
  10.1159/000496660
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09714
[Journal Article] Aortic Arch Calcification and Bone-Associated Molecules in Peritoneal Dialysis Patients.2019
- Author(s)
  Tsukada M, Miwa N, Hanafusa N, Tanaka N, Tsuchiya K, Nitta K.
- Journal Title
  
  Blood Purif
  
  Volume: 47 Issue: Suppl. 2 Pages: 81-87
- DOI
  10.1159/000496657
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09714
[Journal Article] Recent Advances in the Management of Vascular Calcification in Patients with End-Stage Renal Disease.2019
- Author(s)
  Nitta K, Ogawa T, Hanafusa N, Tsuchiya K.
- Journal Title
  
  Contrib Nephrol.
  
  Volume: 198 Pages: 62-72
- DOI
  10.1159/000496532
- ISBN
  9783318064230, 9783318064247
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09714
[Journal Article] Case report: Electron microscopic evaluation of bone from a patient treated with cinacalcet hydrochloride, maxacalcitol, and alfacalcidol for hyperparathyroid bone disease with secondary hyperparathyroidism.2018
- Author(s)
  Yajima A, Tsuchiya K, Bonewald LF, Inaba M, Tominaga Y, Tanizawa T, Ito A, Nitta K.
- Journal Title
  
  Osteoporos Int.
  
  Volume: 29 Issue: 5 Pages: 1203-1209
- DOI
  10.1007/s00198-018-4402-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09714
[Journal Article] Osteocytic perilacunar/canalicular turnover in hemodialysis patients with high and low serum PTH levels.2018
- Author(s)
  Yajima A, Tsuchiya K, Burr DB, Minner DE, Condon KW, Miller CA, Satoh S, Inaba M, Nakayama T, Tanizawa T, Ito A, Nitta K.
- Journal Title
  
  Bone
  
  Volume: 113 Pages: 68-76
- DOI
  10.1016/j.bone.2018.05.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09714
[Journal Article] Fibroblast growth factor 23 is upregulated in the kidney in a chronic kidney disease rat model.2018
- Author(s)
  Sugiura H, Matsushita A, Futaya M, Teraoka A, Akiyama KI, Usui N, Nagano N, Nitta K, Tsuchiya K.
- Journal Title
  
  PLoS One.
  
  Volume: 13 Issue: 3 Pages: 1-22
- DOI
  10.1371/journal.pone.0191706
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09714
[Journal Article] Association Between Risk Factors Including Bone-Derived Biomarkers and Aortic Arch Calcification in Maintenance Hemodialysis Patients.2018
- Author(s)
  Nitta K, Hanafusa N, Okazaki M, Komatsu M, Kawaguchi H, Tsuchiya K
- Journal Title
  
  Kidney Blood Press Res
  
  Volume: 43 Issue: 5 Pages: 1554-1562
- DOI
  10.1159/000494441
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09714
[Journal Article] Management of Osteoporosis in Chronic Kidney Disease2017
- Author(s)
  Nitta K, Yajima A, Tsuchiya K.
- Journal Title
  
  Intern. Med.
  
  Volume: 56 Issue: 24 Pages: 3271-3276
- DOI
  10.2169/internalmedicine.8618-16
- NAID
  130006250492
- ISSN
  0918-2918, 1349-7235
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09714
[Journal Article] FGF23-aKlotho内分泌系と老化2016
- Author(s)
  杉浦秀和, 土谷　健、黒尾　誠
- Journal Title
  
  アンチ・エイジング医学-日本抗加齢医学会雑誌
  
  Volume: 12 Pages: 30-37
- Data Source
  KAKENHI-PROJECT-26461243
[Journal Article] Fibroblast growth factor 23 and soluble Klotho in patients with autosomal dominant polycystic kidney disease.2016
- Author(s)
  Akiyama K, Mochizuki T, Kataoka H, Tsuchiya K, Nitta K.
- Journal Title
  
  Nephrology
  
  Volume: - Issue: 11 Pages: 843-858
- DOI
  10.1111/nep.12862
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461243, KAKENHI-PROJECT-17K09714
[Journal Article] New insight into atherosclerosis in hemodialysis patients: overexpression of scavenger receptor and macrophage colony-stimulating factor genes2016
- Author(s)
  Nishida　M, Ando M, Iwamoto Y, Tsuchiya K, Nitta K.
- Journal Title
  
  Nephron Extra
  
  Volume: 6 Pages: 22-30
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461243
[Journal Article] CKD-MBDにおける骨病変2016
- Author(s)
  矢島愛治、土谷　健、横田博樹、新田孝作
- Journal Title
  
  CLINICAL CALCIUM
  
  Volume: 26 Pages: 69-74
- Data Source
  KAKENHI-PROJECT-26461243
[Journal Article] Transcriptional factor, Mafs and their biological reoles2015
- Author(s)
  Mariko Tsuchiya, Ryoichi Misaka, Kosaku Nitta, Ken Tsuchiya
- Journal Title
  
  World Journal of Diabetes
  
  Volume: 6(1) Issue: 1 Pages: 175-183
- DOI
  10.4239/wjd.v6.i1.175
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23592021
[Journal Article] Klotho/FGF23 Axis in CKD2015
- Author(s)
  Ken Tsuchiyam Nobuo Naganom Kosaku Nitta
- Journal Title
  
  Contrib Nephrol
  
  Volume: 印刷中
- Open Access
- Data Source
  KAKENHI-PROJECT-26461243
[Journal Article] Klotho/FGF23 Axis in CKD.2015
- Author(s)
  Tsuchiya K, Nagano N, Nitta K.
- Journal Title
  
  Contrib Nephrol.
  
  Volume: 185 Pages: 56-65
- DOI
  10.1159/000380970
- ISBN
  9783318054644, 9783318054651
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461243
[Journal Article] Relationship between anaemia management at haemodialysis initiation and patient prognosis.2015
- Author(s)
  Kataoka H, Tsuchiya K, Naganuma T, Okazaki M, Komatsu M, Kimura T, Shiohira S, Kawaguchi H, Nitta K.
- Journal Title
  
  Nephrology (Carlton).
  
  Volume: 20 Issue: S4 Pages: 14-21
- DOI
  10.1111/nep.12639
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461243
[Journal Article] Aortic arch calcification predicts cardiovascular and all-cause mortality in maintenance hemodialysis patients.2014
- Author(s)
  Komatsu M, Okazaki M, Tsuchiya K, Kawaguchi H, Nitta K.
- Journal Title
  
  Kidney Blood Press Res.
  
  Volume: 39(6) Issue: 6 Pages: 658-67
- DOI
  10.1159/000368476
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461243
[Journal Article] Fibroblast growth factor 23/klotho axis in chronic kidney disease.2014
- Author(s)
  Nitta K, Nagano N, Tsuchiya K.
- Journal Title
  
  Nephron Clin Pract.
  
  Volume: 128(1-2) Issue: 1-2 Pages: 1-10
- DOI
  10.1159/000365787
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461243
[Journal Article] Associations between the levels of sclerostin, phosphate, and fibroblast growth factor-23 and treatment with vitamin D in hemodialysis patients with low intact PTH level.2014
- Author(s)
  Asamiya Y, Yajima A, Shimizu S, Otsubo S, Tsuchiya K, Nitta K.
- Journal Title
  
  Osteoporos Int.
  
  Volume: 26(3) Issue: 3 Pages: 1017-28
- DOI
  10.1007/s00198-014-2934-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461243
[Journal Article] Sphingosine-1-phosphate acts as a key molecule in the direct mediation of renal fibrosis.2013
- Author(s)
  Shiohira S, Yoshida T, Sugiura H, Nishida M, Nitta K, Tsuchiya K.
- Journal Title
  
  Physiological Reports
  
  Volume: - Issue: 7 Pages: e00172-e00172
- DOI
  10.1002/phy2.172
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591204
[Journal Article] Neutrophil gelatinase-associated lipocalin is a sensitive biomarker for the early diagnosis of acute rejection after living-donor kidney transplantation.2012
- Author(s)
  Kohei J, Ishida H, Kazunari T, Tsuchiya K, Nitta K.
- Journal Title
  
  Int Urol Nephrol.
  
  Volume: 0 Issue: 4 Pages: 1159-1167
- DOI
  10.1007/s11255-012-0321-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591204
[Journal Article] Metabolic syndrome and risk of progression of chronic kidney disease: a single-center cohort study in Japan.2012
- Author(s)
  Saito T, Mochizuki T, Uchida K, Tsuchiya K, Nitta K.
- Journal Title
  
  Heart Vessels.
  
  Volume: 0 Issue: 3 Pages: 323-329
- DOI
  10.1007/s00380-012-0254-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591204
[Journal Article] Risk factors for vitamin D deficiency in patients with chronic kidney disease.2012
- Author(s)
  Echida Y, Mochizuki T, Uchida K, Tsuchiya K, Nitta K.
- Journal Title
  
  Intern Med.
  
  Volume: 51 Pages: 840-50
- NAID
  130002061872
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591204
[Journal Article] Reduced Klotho expression level in kidney aggravates renal interstitial fibrosis.2012
- Author(s)
  Sugiura H, Yoshida T, Shiohira S, Kohei J, Mitobe M, Kurosu H, Kuro-o M, Nitta K, Tsuchiya K.
- Journal Title
  
  Am J Physiol Renal Physiol.
  
  Volume: 302 Issue: 10 Pages: F1252-F1264
- DOI
  10.1152/ajprenal.00294.2011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591204, KAKENHI-PROJECT-24590115
[Journal Article] Inhibitory effects of the transcription factor Ets-1 on the expression of type I collagen in TGF-β1-stimulated renal epithelial cells.2012
- Author(s)
  Okano K, Hibi A, Miyaoka T, Inoue T, Sugimoto H, Tsuchiya K, Akiba T, Nitta K.
- Journal Title
  
  Mol Cell Biochem.
  
  Volume: 369 Issue: 1-2 Pages: 247-54
- DOI
  10.1007/s11010-012-1388-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591204
[Journal Article] クロトー遺伝子2011
- Author(s)
  土谷　健　杉浦秀和　新田孝作
- Journal Title
  
  カレントテラピー
  
  Volume: 29 Pages: 119-119
- Data Source
  KAKENHI-PROJECT-23591204
[Journal Article] Kosaku Nitta and Atsushi Maeda MafA is a key molecule in glucose and energy balance in the central nervous system and peripheral organs2011
- Author(s)
  Mariko Tsuchiya, Ken Tsuchiya, Kazuki Yasuda, Mikiko Fujita, Akira Takinishi, Maiko Furukawa
- Journal Title
  
  Int. J. Biomed. Sci.
  
  Volume: 7(1) Pages: 19-26
- Data Source
  KAKENHI-PROJECT-20591637
[Journal Article] MafA is a key molecule in glucose and energy balance in the central nervous system and peripheral organs.2011
- Author(s)
  Mariko Tsuchiya, Ken Tsuchiya, Kazuki Yasuda, Mikiko Fujita, Akira Takinishi, Maiko Furukawa, Kosaku Nitta, Atsushi Maeda
- Journal Title
  
  Int.J.Biomed.Sci. in press.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591637
[Journal Article] MafA is a key molecule in glucose and energy balance in the central nervous system and peripheral organs2011
- Author(s)
  Tsuchiya M, Tsuchiya K, Yasuda K, Fujita K, Takinishi A, Furukawa M, Nitta K, Maeda A
- Journal Title
  
  Int J Biomed Sci
  
  Volume: 7 Pages: 19-26
- URL
  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614815/
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591204
[Journal Article] Role of klothos in the pathogenesis ,,,2011
- Author(s)
  Sugiura H, Tsuchiya K, Nitta K.
- Journal Title
  
  J Tokyo Wom Med Univ
  
  Volume: 81 Pages: 236-243
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591204
[Journal Article] Klotho reduces apoptosis in experimental ischaemic acute kidney injury via HSP-70.2010
- Author(s)
  Sugiura H, Yoshida T, Mitobe M, Yoshida S, Shiohira S, Nitta K, Tsuchiya K
- Journal Title
  
  Nephrol Dial Transplant 25
  
  Pages: 60-68
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590965
[Journal Article] Suppression of mafA mRNA with siRNA prevents adipose cell differentiation in 3T3-L1 cells.2009
- Author(s)
  Tsuchiya M, Maeda A, Suzuki A, Yasuda K, Yoshida T, Nitta K, Tsuchiya K*
- Journal Title
  
  Int J Mol Med 23
  
  Pages: 725-732
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590965
[Journal Article] Supression of MafA mRNA with siRNA prevents adipose cell differentiation in 3T3-L1 cells2009
- Author(s)
  Mariko Tsuchiya, Atsushi Maeda, Ayume Suzuki, Kazuki Yasuda, Takumi Yoshida, Kosaku Nitta, Ken Tsuchiya
- Journal Title
  
  Int.J.Mol.Med. 23
  
  Pages: 725-732
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591637
[Journal Article] Suppression of MafA mRNA with siRNA prevents adipose cell differentiation in 3T3-L1 cells2009
- Author(s)
  Tsuchiya M, et al.
- Journal Title
  
  Int J Mol Med 23
  
  Pages: 725-732
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590965
[Journal Article] Supression of MafA mRNA with siRNA prevents adipose cell differentiation in 3T3-L1 cells2009
- Author(s)
  Mariko Tsuchiya, Atsushi Maeda, Ayume Suzuki, Kazuki Yasuda, Takumi Yoshida, Kosaku Nitta and Ken Tsuchiya
- Journal Title
  
  Int. J. Mol. Med.
  
  Volume: 23 Pages: 725-732
- Data Source
  KAKENHI-PROJECT-20591637
[Journal Article] Suppression of MafA mRNA with siRNA prevents adipose cell differentiation in 3T3-L1 cells2009
- Author(s)
  Mariko Tsuchiya, et.al.
- Journal Title
  
  International Journal of Molecular Medicine 23
  
  Pages: 725-732
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591637
[Journal Article] Activating transcription factor 3 ameliorates oxidative stress-induced cell death in human kidney cells and in experimental renal ischemia reperfusion injury.2008
- Author(s)
  Yoshida T, Sugiura H, Mitobe M, Nishimura S, Shirota S, Tsuchiya K, Nobori K, Nitta K, Akiba T
- Journal Title
  
  J Am Soc Nephrol 19
  
  Pages: 217-214
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590965
[Journal Article] The effect of eicosapentaenoic acid on renal function and volume in patients with ADPKD.2008
- Author(s)
  Higashihara E, Nutahara K, Horie S, Muto S, Hosoya T, Hanaoka K, Tsuchiya K, (12人中7番目)
- Journal Title
  
  Nephrol Dial Transplant 23
  
  Pages: 2847-2852
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590965
[Journal Article] Increase of integrin-linked kinase activity in cultured podycytes upon stimulation with plasma from patients with recurrent FSGS.2008
- Author(s)
  Hattori M, Akioka Y, Chikamoto H, Kobayashi N, Tsuchiya K, (8人中5番目)
- Journal Title
  
  Am J Transplant 8
  
  Pages: 1550-1556
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590965
[Journal Article] Protective effect of carbon monoxide donor compounds in endotoxin-induced acute renal failure.2007
- Author(s)
  Shiohira S, Yoshida T, Sugiura H, Shirota S, Tsuchiya K, Akiba T, Nitta K
- Journal Title
  
  Am J Nephrol 27
  
  Pages: 441-446
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590965
[Journal Article] In vivo suppression of mafA mRNA with siRNA and analysis of the resulting alteration of the gene expression profile in mouse pancreas by the microarray method2007
- Author(s)
  M. Tsychiya, K. Yasuda, K. Tsuchiya, et. al.
- Journal Title
  
  Biochemical and Biophysical Research Communication 356
  
  Pages: 129-135
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17591443
[Journal Article] In vivo suppression of mafA mRNA with siRNA and analysis of the resulting alteration of the gene expression profile in mouse pancreas by the microarray method2007
- Author(s)
  M. Tsuchiya, T. Yoshid, S. Taniguchi, K. Yasuda, A. Maeda, A. Hayashi, K. Tsuchiya, et. al.
- Journal Title
  
  Biochemical Biophysical Research Communications 356
  
  Pages: 129-135
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17591443
[Journal Article] In vivo suppression of mafA mRNA with siRNA and analysis of the resulting alteration of the gene expression profile in mouse pancreas by the microarray method.2007
- Author(s)
  M Tsuchiya
- Journal Title
  
  Biochem Biophy Res Commun 356
  
  Pages: 129-135
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590965
[Journal Article] In vivo suppression of mafA mRNA with siRNA and analysis of the resulting alteration of the gene expression profile in mouse pancreas by the microarray method.2007
- Author(s)
  Tsuchiya M, Yoshida T, Taniguchi S, Yasuda K, Maeda A, Hayashi A, Tanaka J, Shigemoto M, Nitta K, Tsuchiya K*
- Journal Title
  
  Biochem Biophys Res Commun 356
  
  Pages: 29-135
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590965
[Journal Article] In vivo suppression of mafA mRNA with siRNA and analysis of the resulting alteration of the gene expression profile in mouse pancreas by the microarray method2007
- Author(s)
  Mariko, Tsuchiya, Takumi, Yoshida, Shigeki, Taniguchi, Kazuki, Yasuda, Atsushi, Maeda, Akiko, Hayashi, Junko Tanaka, Mutsuo, Shigemoto, Kohsaku, Nitta, Ken, Tsuchiya
- Journal Title
  
  Biochemical Biophysical Research Communications 356
  
  Pages: 129-135
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591443
[Journal Article] Potential roles of mafs in cell lineage and developing pancreas2006
- Author(s)
  TSUCHIYA M, Yasuda K, Tsuchiya K et al.
- Journal Title
  
  Pancreas 32(4)
  
  Pages: 408-416
- Data Source
  KAKENHI-PROJECT-17591443
[Journal Article] Potential roles of large mafs in cell lineages and developing pancreas2006
- Author(s)
  Mariko, Tsuchiya, Shigeki, Taniguchi, Kazuki, Yasuda, Kosaku, Nitta, Atsushi, Maeda, Mutsuo, Shigemoto, Ken Tsuchiya
- Journal Title
  
  Pancreas 32
  
  Pages: 408-416
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591443
[Journal Article] Potential roles of large mafs in cell lineages and developing pancreas2006
- Author(s)
  M. Tsuchiya, S. Taniguchi, K. Yasuda, K. Tsuchiya, et. al.
- Journal Title
  
  Ppancreas 32
  
  Pages: 408-416
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17591443
[Journal Article] In vivo suppression of mafs mRNA using siRNA and resulting alteration of gene expression profile in mouse pancreas by microarray analysis2006
- Author(s)
  Tsuchiya M, et al.
- Journal Title
  
  pnacreas 33
  
  Pages: 503-503
- Data Source
  KAKENHI-PROJECT-17591443
[Journal Article] In vivo suppression of mafs mRNA using siRNA and resulting alterarion of gene expression profile in mouse pancreas by microarray analysis2006
- Author(s)
  Tsuchiya M, et al.
- Journal Title
  
  Diabetes 55(Supple)
- Data Source
  KAKENHI-PROJECT-17591443
[Journal Article] Potential Role of Large Mafs in Cell Lineages in Developing Pancreas2005
- Author(s)
  Mariko Tsuchiya et al.
- Journal Title
  
  Diabetes 54 Supple1
- Data Source
  KAKENHI-PROJECT-17591443
[Journal Article] Potential Roles of Large Mafs in the Developing Pancreas2005
- Author(s)
  Mariko Tsuchiya et al.
- Journal Title
  
  Pancreas 31(4)
  
  Pages: 474-478
- Data Source
  KAKENHI-PROJECT-17591443
[Journal Article] Effect of GLP-1(Glucogon-like Peptide1:7-36 Amide) on porcine pancreatic cell proliferation and insulin secretion2004
- Author(s)
  Nagai K, Tsuchiya K, Ezaki T, Tsuchiya M, Ohgawara H
- Journal Title
  
  Pancreas 28
  
  Pages: 138-145
- Data Source
  KAKENHI-PROJECT-14571236
[Journal Article] Analysis of gene expression and insulin secretion by monolayer-forming adult porcine pancreatic endocrine cell2003
- Author(s)
  Tsuchiya M
- Journal Title
  
  Pancreas 26
  
  Pages: 71-75
- NAID
  10016163415
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571236
[Journal Article] Analysis of gene expression and insulin secretion by monolayer-forming adult porcine pancreatic endocrine cells2003
- Author(s)
  Tsuchiya M
- Journal Title
  
  Pancreas 26
  
  Pages: 71-75
- NAID
  10016163415
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571236
[Journal Article] 再生医療の最前線膵再生2002
- Author(s)
  土谷まり子
- Journal Title
  
  小児内科 34
  
  Pages: 94-92
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571236
[Journal Article] MafA is a key molecule in glucose and energy balance in the central Nervous system and peripheral organs
- Author(s)
  Mariko Tsuchiya, Ken Tsuchiya, Kazuki Yasuda, et.al.
- Journal Title
  
  International Journal of Biomedical Science
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591637
[Presentation] Additional damage by phosphorus loading accdlerates the progression of CKD model by the accumulation of minor kidney injury in Klotho deficit mice2019
- Author(s)
  Tsuchiya K, Sugiura H, Hanafusa N, Tsukada M, Nitta K
- Organizer
  ERA-ETDA ブタペストハンガリー
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09714
[Presentation] MODULATION OF KLOTHO/FGF23 EXPRESSION LEVEL BY PHOSPHORUS LOADING IN THE MOUSE MODEL MIMICKING TO INTEGRATED AKI TO CKD SYNDROME2018
- Author(s)
  Tsuchiya K, Sugiura H, Nishida M, Nitta K
- Organizer
  ERA EDTA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09714
[Presentation] 腎繊維化モデルにおけるfibulin-7の発現変化2017
- Author(s)
  杉浦秀和, 常住淳, 土谷健, 新田孝作, 柳沢裕美
- Organizer
  日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-17K09714
[Presentation] Phosphorus is an exacerbation factor in the progression of CKD model by the accumulation of small kidney injury in Klotho deficit mice.2017
- Author(s)
  Tsuchiya K, Sugiura H, Nishida M, Nitta K
- Organizer
  American Society of Nephrology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09714
[Presentation] Osteocytic Perilacunar/Canalicular Turnover in Dialysis Patients with High and Low Serum PTH Levels2017
- Author(s)
  Yajima A, Tsuchiya K, Nitta K
- Organizer
  American Society of Nephrology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09714
[Presentation] Repeated minor AKI accelerates renal fibrosis and dysfunction in klotho deficit mice2015
- Author(s)
  Tsuchiya K, et al.
- Organizer
  American Society of Nephrology
- Place of Presentation
  San Diego USA
- Year and Date
  2015-11-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461243
[Presentation] CKDの病態生理と心腎連関2014
- Author(s)
  土谷　健
- Organizer
  第17回生活習慣病を考える会
- Place of Presentation
  東京　新宿区京王プラザホテル
- Year and Date
  2014-07-30
- Invited
- Data Source
  KAKENHI-PROJECT-26461243
[Presentation] AKI CKD Klotho2013
- Author(s)
  土谷　健
- Organizer
  第24回急性血液浄化学会　教育セミナー
- Place of Presentation
  札幌
- Invited
- Data Source
  KAKENHI-PROJECT-23591204
[Presentation] Biological properties of klotho in the anti-fibrotic process and establishment of cell integrity in coordination with cell signaling pathway /translocation of membrane transporters2013
- Author(s)
  Tsuchiya K, Shiohira S, Nishida M, Okano K, Sugiura H, Nitta K
- Organizer
  American Society of Nephrology
- Place of Presentation
  Atlanta, USA
- Year and Date
  2013-11-08
- Data Source
  KAKENHI-PROJECT-23591204
[Presentation] Klotho coordinates with transcriptional factors, Mafs in the differentiation and establishment of cell integrity of pancreatic /adipose cells2013
- Author(s)
  Mariko Tsuchiya, Ryoichi Misaka, Kosaku Nitta, Ken Tsuchiya
- Organizer
  73rd scientific sessions of American Diabes Association
- Place of Presentation
  Chicago
- Invited
- Data Source
  KAKENHI-PROJECT-23592021
[Presentation] Biological Properties of Klotho in the Anti-Fibrotic Process and Establishment of Cell Integrity in Coordination with Cell Signaling Pathway /Translocation of Membrane Transporters2013
- Author(s)
  Ken Tsuchiya, MD, PhD, Shunji Shiohira, MD, PhD, Miki Nishida, MD, Kazuhiro Okano, MD, PhD, Hidekazu Sugiura, MD, PhD, Kosaku Nitta, MD, PhD
- Organizer
  American Society of Nephrology
- Place of Presentation
  USA Atlanta
- Data Source
  KAKENHI-PROJECT-23591204
[Presentation] siRNAとスクラッチアッセイによるSphingosine-1-phosphate receptor 3と腎臓線維化の解明2013
- Author(s)
  潮平俊治、芳田工、公平順子、杉浦秀和、新田孝作、土谷健
- Organizer
  日本腎臓学会学術総会
- Place of Presentation
  東京
- Year and Date
  2013-05-10
- Data Source
  KAKENHI-PROJECT-23591204
[Presentation] Klotho is involved in the differentiation and establishment of cell integrity of pancreatic/adipose cell in coordination with transcriptional factor, mafs2013
- Author(s)
  Tsuchiya M, Misaka R, Nitta K, Tsuchiya K
- Organizer
  American Diabetes Association
- Place of Presentation
  San Diego, USA
- Year and Date
  2013-06-21
- Data Source
  KAKENHI-PROJECT-23591204
[Presentation] 1) Klotho is involved in the differentiation and establishment of cell integrity of pancreatic/adipose cell in coordination with transcriptional factor, mafs2013
- Author(s)
  Tsuchiya M, Misaka R, NItta K, and Tsuchiya K.
- Organizer
  American Diabetes Association
- Place of Presentation
  USA San Diego
- Data Source
  KAKENHI-PROJECT-23591204
[Presentation] Scratch assayを用いたKlothoの抗線維化作用の検討2013
- Author(s)
  土谷健、杉浦秀和、潮平俊治、公平順子、鈴木美貴、望月俊雄、新田孝作
- Organizer
  日本腎臓学会学術総会
- Place of Presentation
  東京
- Year and Date
  2013-05-10
- Data Source
  KAKENHI-PROJECT-23591204
[Presentation] Sphingosine-1-phosphateレセプター3は腎臓に繊維化に重要である2012
- Author(s)
  潮平俊治、芳田工、公平順子、杉浦秀和、三戸部倫大、新田孝作、土谷健
- Organizer
  日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2012-06-01
- Data Source
  KAKENHI-PROJECT-23591204
[Presentation] Klotho発現と腎線維化、TGF betaとの関連2012
- Author(s)
  杉浦秀和、芳田工、公平順子、三戸部倫大、潮平俊治、土谷健、新田孝作
- Organizer
  日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2012-06-01
- Data Source
  KAKENHI-PROJECT-23591204
[Presentation] Sphingosine 1-phosphate/sphingosine 1-phosphate receptor 3, potential mediators of renal fibrosis, are assessed by siRNA and scratch assay2012
- Author(s)
  Shiohira S, Yoshida T, Kohei J, Sugiura H, Nitta K, Tsuchiya K
- Organizer
  American Society of Nephrology
- Place of Presentation
  San Diego USA
- Year and Date
  2012-11-01
- Data Source
  KAKENHI-PROJECT-23591204
[Presentation] 1) The WNT signaling pathway plays pivotal roles in the differentiation of pancreatic cells in coordination with maf transcriptional factors.2012
- Author(s)
  Tsuchiya M, Tsuchiya K et al.
- Organizer
  American Diabetes Association
- Place of Presentation
  Philadelphia
- Data Source
  KAKENHI-PROJECT-23591204
[Presentation] 3) NGAL and cystatin C elevations were associated with short term graft function in overweight recipients after kidney transplantation.2012
- Author(s)
  Kohei J, Tsuchiya K, Nitta K et al.
- Organizer
  The American Society of Nephrology
- Place of Presentation
  San Diego
- Data Source
  KAKENHI-PROJECT-23591204
[Presentation] The WNT signal pathway plays pivotal roles in the differentiaion of pancreatic cells in cordination with maf transcriptional factors2012
- Author(s)
  Mariko Tsuchiya
- Organizer
  71st scientific sessions of American Diabetes Association
- Place of Presentation
  Philadelphia, PA USA
- Invited
- Data Source
  KAKENHI-PROJECT-23592021
[Presentation] 1) Assessment of anti-fibrotic effects of klotho with a high-throughput cell migration assay using scratch wound healing.2012
- Author(s)
  Tsuchiya K, Sugiura H, Nitta K et al.
- Organizer
  The American Society of Nephrology
- Place of Presentation
  San Diego
- Data Source
  KAKENHI-PROJECT-23591204
[Presentation] Assessment of anti-fibrotic effects of klotho with a high-throughput cell migration assay using scratch wound healing2012
- Author(s)
  Tsuchiya K, Sugiura H, Yosida T, Shiohira S, Nitta K
- Organizer
  American Society of Nephrology
- Place of Presentation
  San Diego USA
- Year and Date
  2012-11-01
- Data Source
  KAKENHI-PROJECT-23591204
[Presentation] Sphingosine-1-phosphateは腎臓の線維化を直接的・間接的に促進する因子のひとつである2011
- Author(s)
  潮平俊治、芳田工、公平順子、杉浦秀和、三戸部倫大、土谷健、新田孝作
- Organizer
  日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2011-06-15
- Data Source
  KAKENHI-PROJECT-23591204
[Presentation] Klotho発現と腎線維化、TGF betaとの関連2011
- Author(s)
  杉浦秀和、芳田工、三戸部倫大、潮平俊治、土谷健、新田孝作
- Organizer
  日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2011-06-15
- Data Source
  KAKENHI-PROJECT-23591204
[Presentation] S1PR3 is pivotal factor in fibrosis in the kidney2011
- Author(s)
  Shiohira S, Yoshida T, Kohei J,Sugiura H, Mitobe M, NittaK, Tsuchiya K
- Organizer
  American Society of Nephrology
- Place of Presentation
  Philadelphia USA
- Year and Date
  2011-11-08
- Data Source
  KAKENHI-PROJECT-23591204
[Presentation] Transcription factor mafB and a functional link to E-cadherin expression in b cell differentiation2011
- Author(s)
  Mariko Tsuchiya, Ken Tsuchiya, Kosaku Nitta, Atsushi Maeda
- Organizer
  71st scientific sessions of American Diabetes Association
- Place of Presentation
  San Diego, CA
- Data Source
  KAKENHI-PROJECT-20591637
[Presentation] Transcription factor mafB and functional link to E-cadherin expression in b cell differentiation2011
- Author(s)
  Mariko Tsuchiya, Ken Tsuchiya, Kosaku Nitta, Atsushi Maeda
- Organizer
  71st scientific sessions of American Diabetic Association(招待講演)
- Place of Presentation
  San Diego, CA
- Data Source
  KAKENHI-PROJECT-23592021
[Presentation] Reduced Klotho expression level in kidney aggravates renal interstitial fibrosis2011
- Author(s)
  Sugiura H, Yoshida T, Kohei J, Shiohira S,Mitobe M, Tsuchiya K, Nitta K
- Organizer
  American Society of Nephrology
- Place of Presentation
  Philadelphia USA
- Year and Date
  2011-11-08
- Data Source
  KAKENHI-PROJECT-23591204
[Presentation] Transcription factor MafB is implicated in regulation of expression of lipocalin2 and EMT-related genes as well as genes composing of developing pancreas2010
- Author(s)
  Mariko Tsuchiya, Atsushi Meda Kosaku Nitta, Ken Tsuchiya
- Organizer
  70^<th> scientific session of American Diabetic Association
- Place of Presentation
  Orlando, FL USA
- Data Source
  KAKENHI-PROJECT-20591637
[Presentation] Transcription factor mafB is implicated in regulation of expression of lipocalin2 and EMT-related genes as well as genes composing of developing pancreas2010
- Author(s)
  Mariko Tsuchiya, Atsushi Maeda, Kosaku Nitta, Ken Tsuchiya
- Organizer
  70^<th> scientific session of American Diabetic Association
- Place of Presentation
  Orland, FL
- Data Source
  KAKENHI-PROJECT-20591637
[Presentation] Transcription factor mafB is implicated in regulation of expression of lipocalin2 and EMT-related genes as well as genes composing of developing pancreas.2010
- Author(s)
  Mariko Tsuchiya
- Organizer
  70^<th> scientific session of American Diabetic Association
- Place of Presentation
  Orland, FL
- Data Source
  KAKENHI-PROJECT-20591637
[Presentation] Functional roles of transcriptional factor mafB in vivo assessed by siRNA technique and microarray analysis2009
- Author(s)
  Mariko Tsuchiya
- Organizer
  45^<th> EASD Annual Meeting
- Place of Presentation
  Vienna
- Data Source
  KAKENHI-PROJECT-20591637
[Presentation] Functional role of transcription factor of mafB in vivo assessed by siRNA techinique and microarray analysis2009
- Author(s)
  Mariko Tsuchiya, Ayume Suzuki, Akiko Hayashi, Junko Tanaka, Ken Tsuchiya Atsushi Maeda
- Place of Presentation
  Viena
- Data Source
  KAKENHI-PROJECT-20591637
[Presentation] MafA is a key molecule in glucose and energy balance in the central nervous system as in the peripheral organs2009
- Author(s)
  Mariko Tsuchiya
- Organizer
  69^<th> Scientific sessions of American Diabetes Association
- Place of Presentation
  New Orleans, LA
- Data Source
  KAKENHI-PROJECT-20591637
[Presentation] MafA is a key molecule in glucose and energy balance in the central nervous system as in the peripheral organs2009
- Author(s)
  Mariko Tsuchiya, Ken Tsuchiya, Kazuki Yasuda, Ayume Suzuki, Atsushi Maeda
- Organizer
  69^<th> scientific sessions of American Diabetic Association
- Place of Presentation
  New Orleans, LA
- Data Source
  KAKENHI-PROJECT-20591637
[Presentation] MafA is a key molecule in glucose and energy balance in the central nervous system as in the peripheral organs.2009
- Author(s)
  Mariko Tsuchiya
- Organizer
  69^<th> scientific sessions of American Diabetic Association
- Place of Presentation
  New Orleans, LA
- Data Source
  KAKENHI-PROJECT-20591637
[Presentation] Functional role of transcription factor of mafB in vivo assessed by siRNA techinique and microarray analysis.2009
- Author(s)
  Mariko Tsuchiya
- Place of Presentation
  Viena
- Data Source
  KAKENHI-PROJECT-20591637
[Presentation] 「研究成果報告書概要(和文)」より2008
- Author(s)
  Mariko Tsuchiya, et. al.
- Organizer
  68th scientific session of American Diabetic Association
- Place of Presentation
  San Francisco
- Year and Date
  2008-06-06
- Data Source
  KAKENHI-PROJECT-17591443
[Presentation] Suppression of the left-right determinant inv gene using RNA Interference technique2008
- Author(s)
  Ken Tsuchiya
- Organizer
  Forefront in Nephrology
- Place of Presentation
  Montreal Canada
- Year and Date
  2008-04-10
- Data Source
  KAKENHI-PROJECT-19590965
[Presentation] Suppression of MafA mRNA with siRNA Attenuates Morpholpgy and Function of Adipocyte Differentiation by 3T3-L1Cells2008
- Author(s)
  Mariko Tsuchiya
- Organizer
  68^<th> scientitific sessions of American Diabetic Association
- Place of Presentation
  San Francisco, CA USA
- Data Source
  KAKENHI-PROJECT-20591637
[Presentation] Supression of mafA mRNA with siRNA attenuates Morphology and function of adipocyte differentiation by 3T3-L1 cells2008
- Author(s)
  Mariko, Tsuchiya, Atsushi, Maeda, Kazuki, Yasuda, Ken, Tsuchiya
- Organizer
  68th scientific sessions of American Diabetic Association
- Place of Presentation
  San Francisco
- Year and Date
  2008-06-10
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591443
[Presentation] Supression of mafA mRNA attenuates morphology and functions of adipocyte differentiation by 3T3-L1 cells.2008
- Author(s)
  Mariko Tsuchiya
- Organizer
  68^<th> scientific sessions of American Diabetic Association
- Place of Presentation
  San Francisco, CA
- Data Source
  KAKENHI-PROJECT-20591637
[Presentation] Supression of mafA mRNA attenuates morphology and functions of adipocyte differentiation by 3T3-L1 cells2008
- Author(s)
  Mariko Tsuchiya, Atsushi Maeda, Kazuki Yasuda, Ken Tsuchiya
- Organizer
  68^<th> scientific sessions of American Diabetic Association
- Place of Presentation
  San Francisco, CA
- Data Source
  KAKENHI-PROJECT-20591637
[Presentation] Supression of mafs expression by the siRNA technique alters the geneprofile related to pancreatic endocrine hormone and adipocytokine in vivo and in vitro2007
- Author(s)
  Mariko Tsuchiya
- Organizer
  38th annual meeting of American Pancreatic Association
- Place of Presentation
  Chicago
- Year and Date
  2007-11-02
- Data Source
  KAKENHI-PROJECT-17591443
[Presentation] 「研究成果報告書概要(和文)」より2007
- Author(s)
  Mariko Tsuchiya, et. al.
- Organizer
  The liver meeting 2007 of American Association of for the study of liver
- Place of Presentation
  Chicago
- Year and Date
  2007-11-02
- Data Source
  KAKENHI-PROJECT-17591443
[Presentation] In vivo suppression of mafA mRNA with siRNA and alteration of the gene expression profile, especially of adipocytokine genes, in mouse liver analyzed by the microarray method2007
- Author(s)
  Mariko, Tsuchiya, Atsushi, Maeda, Junko, Tanaka, Ken, Tsuchiya
- Organizer
  The liver meeting 2007 of American Association for the study of liver
- Place of Presentation
  Boston
- Year and Date
  2007-11-06
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591443
[Presentation] 「研究成果報告書概要(和文)」より2007
- Author(s)
  Mariko Tsuchiya, et. al.
- Organizer
  67th scientific session of American Diabetic Association
- Place of Presentation
  Chicago
- Year and Date
  2007-06-24
- Data Source
  KAKENHI-PROJECT-17591443
[Presentation] Gene profile related to mafs in vivo by siRNA techinique and microarray analysis in physiological and pathophysiological metabolic responses2007
- Author(s)
  Mariko, Tsuchiya, Atsushi, Maeda, Akiko, Hayashi, Junko, Tanaka, Takumi, Yoshida, Shigeki, Taniguchi, Kazuki Yasuda, Kosaku, Nitta, Ken, Tsuchiya
- Organizer
  67th scientific sessions of American Diabetic Association
- Place of Presentation
  Chicago
- Year and Date
  2007-06-24
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591443
[Presentation] Supression of mafs expression by the siRNA techinique alters the gene profile related to pancreatic endocrine hormone and adipocytokine in vivo and vitro2007
- Author(s)
  Mariko, Tsuchiya, Akiko, Hayashi, Junko, Tanaka, Atsushi, Maeda, Ken, Tsuchiya
- Organizer
  38th annual meeting of American Pancreatic Association
- Place of Presentation
  Chicago
- Year and Date
  2007-11-02
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591443
[Presentation] Gene profile related to mafs in vivo by siRNA technique and microarray analysis in physiological and pathophysiological metabolic responses2007
- Author(s)
  Mariko Tsuchiya
- Organizer
  67th scientificsessions of American Diabetic Association
- Place of Presentation
  Chicago
- Year and Date
  2007-06-24
- Data Source
  KAKENHI-PROJECT-17591443
[Presentation] In vivo suppression of mafs mRNA using siRNA and resulting alteration of gene expression profile in mouse pancreas by microarray analysis2006
- Author(s)
  Mariko, Tsuchiya, Atsushi, Maeda, Mutsuo, Shigemoto, Ken, Tsuchiya
- Organizer
  37th annual meeting of American Pancreatic Association
- Place of Presentation
  Chicago
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591443
[Presentation] In vivo suppression of mafs mRNA using siRNA and resulting alteration of gene expression profile in mouse pancreas by microarray analysis2006
- Author(s)
  Mariko, Tsuchiya, Takumi, Yoshida, Shigeki, Taniguchi, Kazuki, Yasuda, Atsushi, Maeda, Mutsuo, Shigemoto, Ken Tsuchiya
- Organizer
  66th scientific sessions of American Diabetic Association
- Place of Presentation
  Washington
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591443
[Presentation] 「研究成果報告書概要(和文)」より2006
- Author(s)
  Mariko Tsuchiya, et. al.
- Organizer
  66th scientific session of American Diabetic Association
- Place of Presentation
  Washington
- Year and Date
  2006-06-09
- Data Source
  KAKENHI-PROJECT-17591443
[Presentation] 「研究成果報告書概要(和文)」より2005
- Author(s)
  Mariko Tsuchiya, et. al.
- Organizer
  65th scientific session of American Diabetic Association
- Place of Presentation
  San Diego
- Year and Date
  2005-06-10
- Data Source
  KAKENHI-PROJECT-17591443
[Presentation] Atsushi Maeda, Mutsuo Shigemoto and Katsuko Yamashita Potential role of large mafs in cell lineages in developing pancreas2005
- Author(s)
  Mariko, Tsuchya, Ken, Tsuchiya, Shigeki, Taniguchi, Kazuki, Yasuda
- Organizer
  65th scientific sessions of American Diabetic Association
- Place of Presentation
  San Diego
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591443
[Presentation] Mutsuo Shigemoto Potential role of large mafs in the developing pancreas2005
- Author(s)
  Mariko, Tsuchiya, Ken, Tsuchiya, Atsushi, Maeda
- Organizer
  36th annual meeting of American Pancreatic Association
- Place of Presentation
  Chicago
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591443
[Presentation] Large Mafs Modulate Autophagic Activity and ER-stress in Diabetic Pancreas
- Author(s)
  Mariko Tsuchiya, Ryoichi MIsaka, KosakuNitta, Ken Tsuchiya
- Organizer
  American Diabetes Association 75th Scientific Sessions
- Place of Presentation
  Boston, MA
- Year and Date
  2015-06-05 – 2015-06-09
- Data Source
  KAKENHI-PROJECT-23592021
[Presentation] Pre-dialysis to dialysis pathophysiology of Klotho, P, Potassium
- Author(s)
  Ken Tsuchiya
- Organizer
  The International Society for Hemodialysis
- Place of Presentation
  上海　中国
- Year and Date
  2014-09-12 – 2014-09-14
- Invited
- Data Source
  KAKENHI-PROJECT-26461243

1. TSUCHIYA Mariko (00266826)

# of Collaborated Projects: 10 results

# of Collaborated Products: 103 results
2. MOCHIZUKI Toshio (00277120)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. YOSHIDA Takumi (80297449)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
4. 大河原久子 (10075468)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. SHIOHIRA Shunji (00529232)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
6. NIHEI Hiroshi (30124308)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. NITTA Kosaku (50241071)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. YOKOYAMA Takahiko (70191525)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. HATTORI Motoshi (50192274)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. AKIOKA Yuko (90212422)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. ITO Katsumi (90056771)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. CHIKAMOTO Hiroko (80307529)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. YASUDA Kazuki (80311611)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
14. 代田さつき (10366338)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 浅宮有香理 (40596566)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 西村佐代子 (00349721)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

tsuchiya ken 土谷 健

TSUCHIYA Ken 土谷 健

土屋 健 ツチヤ ケン

土谷 健 ツチヤ ケン

Research Projects

Research Products

Co-Researchers

Elucidation and therapeutic intervention of the mechanism of CKD onset and aggravation due to repeated and accumulated mild renal damagesPrincipal Investigator

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Significance of Klotho as a target molecule for CKD progression, severe process and early interventionPrincipal Investigator

Principal Investigator

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Treating strategie for CKD with Klotho as a targetting moleculePrincipal Investigator

Principal Investigator

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Functional analysis of glucose related transcriptional factors using direct RNA sequence and mechanosensor

Principal Investigator

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Reserch of large maf transcription factors on pancreatic cell and preadipocyte differentiation

Principal Investigator

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Making conditional knockout mouse of the gene coding inversin and the significance of inversion in the cilia-dependent renal diseasePrincipal Investigator

Principal Investigator

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Study on pancreatic cell lineage of growth and differentiation in culture cells and tissue

Principal Investigator

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Production of inv (Inversion of embryonic turning) gene knockout mouse and development of disease related animal modelsPrincipal Investigator

Principal Investigator

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Analysis by cDNA array of altered gene expression in mouse cultured podocytes in response to plasma from recurrent-focal segmental glomerulosclerosis patients

Principal Investigator

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Development of pancreatic stem cell and β-cell for cell therapy

Principal Investigator

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Functional analisis of invgene which determines lef-right axis and relates to renal developmentPrincipal Investigator

Principal Investigator

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Research Field

Research Institution

膵幹細胞のβ細胞への分化増殖に関する転写因子の検討とハイブリッド型人工膵の開発

Principal Investigator

Project Period (FY)

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Research Institution

Molecular analysis of cystic kidney formed transgenic mouse generated by insertional mutationPrincipal Investigator

tsuchiya ken 土谷健

TSUCHIYA Ken 土谷健

土屋健ツチヤケン

土谷健ツチヤケン