Itoi Manami 糸井マナミ

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ITOI Manami 糸井マナミ

系井マナミイトイマナミ

ITYOI Manami 糸井マナミ

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Researcher Number	00257833
Other IDs
Affiliation (Current)	2025: 明治国際医療大学, 基礎医学講座, 教授
Affiliation (based on the past Project Information) *help	2025: 明治国際医療大学, 基礎医学講座, 教授 2008 – 2010: Meiji College of Oriental Medicine, 医学教育研究センター, 准教授 2005: Meiji University of Oriental Medicine, Assistant Professor, 講師 2002 – 2005: 明治鍼灸大学, 鍼灸学部, 講師
Review Section/Research Field	Principal Investigator Immunology Except Principal Investigator Basic Section 56010:Neurosurgery-related / Immunology / Biological Sciences
Keywords	Principal Investigator 再生医療 / 免疫学 / Foxn1 / 再生医学 / 細胞・組織 / 発生・分化 Except Principal Investigator 3次元オルガノイド / フェロトーシス / 腫瘍微小環境 / 中枢神経系原発悪性リンパ腫 … More / Organogenesis / Cell migration / Chemokine receptor / Chemokine / T progenitor cells / Thymus / Mouse / 血管形成 / ケモカイン・レセプター / T前駆細胞 / 器官形成 / 細胞移入 / ケモカインレセプター / ケモカイン / T系前駆細胞 / 胸腺 / マウス / Foxn1 / 再生医学 / 細胞・組織 / 発生・分化 / 免疫学 Less

Ferrroptosis in the primary central nervous sytem lymphoma cells amidst tumor microenvironment.
- Principal Investigator
  
  武内勇人
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Kyoto Prefectural University of Medicine
Foxn1陽性胸腺上皮前駆細胞による胸腺の自己形成
- Principal Investigator
  
  AMAGAI Takashi
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Meiji College of Oriental Medicine
Analysis of TEC progenitors and their niche in the adult thymiPrincipal Investigator
- Principal Investigator
  
  ITOI Manami
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Meiji College of Oriental Medicine
Studies on chemokines and chemokine receptors concerning migration of T-progenitor cells into the thymus anlagen
- Principal Investigator
  
  AMAGAI Takashi
- Project Period (FY)
  2002 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Meiji University of Oriental Medicine

All 2011 2010 2009 2008 2005 2003

All Journal Article Presentation

[Journal Article] Polycomb group gene Bmi1 plays a role in the growth of thymic epithelial cells.2011
- Author(s)
  Guo Y, Miyazaki M, Itoi M, Satoh R, Iwama A, Amagai T, Kawamoto H, Kanno M
- Journal Title
  
  Eur J Immunol. 41(4)
  
  Pages: 1098-1107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590495
[Journal Article] Foxn1 is essential for vascularization of the murine thymus anlage.2010
- Author(s)
  Mori K, Itoi M, Tsukamoto N, Amagai T
- Journal Title
  
  Cell Immunol. 260
  
  Pages: 66-69
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590495
[Journal Article] Thymic cysts originate from Foxn1 positive thymic medullary epithelium.2010
- Author(s)
  Vroegindeweij E, Crobach S, Itoi M, Satoh R, Zuklys S, Happe C, Germeraad WT, Cornelissen JJ, Cupedo T, Hollander GA, Kawamoto H, van Ewijk W
- Journal Title
  
  Mol Immunol. 47(5)
  
  Pages: 1106-1113
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590495
[Journal Article] Notch activation in thymic epithelial cells induced development of thymic microenvironments.2009
- Author(s)
  Masuda K, Germeraad WT, Satoh R, Itoi M, Ikawa T, Minato N, Katsura Y, van Ewijk W, Kawamoto H
- Journal Title
  
  Mol Immunol. 46(8-9)
  
  Pages: 1756-1767
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590495
[Journal Article] Thymic anlage is colonized by progenitors restricted to T, NK and dendritic cell lineages.2005
- Author(s)
  Masuda, K., Itoi, M., et al.
- Journal Title
  
  Journal of Immunology 174.5
  
  Pages: 2525-2532
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570288
[Journal Article] Thymic anlage is colonized by progenitors restricted to T, NK and dendritic cell lineages.2005
- Author(s)
  Masuda, K, Itoi, M., Amagai, T., Minato, N., Katsura, Y., Kawamoto, H.
- Journal Title
  
  J.Immunol. 174
  
  Pages: 2525-2532
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570288
[Journal Article] Lack of delta like 1 and 4 expressions in nude thymus anlages.2005
- Author(s)
  Tskamoto, N., Itoi, M., Nishikawa, M., Amagai, T.
- Journal Title
  
  Cellular Immunol. 234
  
  Pages: 77-80
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570288
[Journal Article] Polycomb group gene mel-18 regulates early T progenitor expansion by maintaining the expression of Hes-1, a target of the Notch pathway.2005
- Author(s)
  Miyazaki, M., Kawamoto, H., Kato, Y., Itoi, M., Miyazaki, K., Masuda, K., Tashiro, S., Ishihara, H., Igarashi, K., Amagai, T., Kanno, R., Kanno, M.
- Journal Title
  
  J.Immunol. 174
  
  Pages: 2507-2516
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570288
[Journal Article] A role of CXC chemokine ligand 12/stromal cell-derived factor-1/pre-B cell growth stimulating factor and its receptor CXCR4 in fetal and adult T cell development in vivo.2003
- Author(s)
  Ara, T., Itoi, M., et al.
- Journal Title
  
  Journal of Immunology 170.9
  
  Pages: 4649-4655
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570288
[Journal Article] Development of thymic microenvironments in vitro is oxygen-dependent and requires permanent presence of T-cell progenitors.2003
- Author(s)
  Germeraad, W.T.V., Kawamoto, H., Itoi, M., Jiang, Y., Amagai, T., Katsura, Y., van Ewijk, W.
- Journal Title
  
  J.Histochem.Cytokem. 51
  
  Pages: 1225-1235
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570288
[Journal Article] A role of CXC chemokine ligand 12/stromal cell-derived factor-1/Pre-B cell growth stimulating factor and its reseptor CXCR4 in fetal and adult T cell development in vivo.2003
- Author(s)
  Ara, I., Itoi, M., Kawabata, K., Egawa, T., Tokoyoda, K., Sugiyama, T., Fujii, N., Amagai, T., Nagasawa, T.
- Journal Title
  
  J Immunol 170
  
  Pages: 4649-4655
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570288
[Presentation] Foxn1 is differentially required for cTEC and mTEC function.2011
- Author(s)
  糸井マナミ
- Organizer
  EUThyme-Rolduc Meeting.
- Place of Presentation
  Leeuwenhorst, NL.
- Year and Date
  2011-05-22
- Data Source
  KAKENHI-PROJECT-20590495
[Presentation] 胸腺皮質および髄質上皮細胞の分化における転写因子Foxn1の役割2011
- Author(s)
  糸井マナミ
- Organizer
  日本胸腺研究会
- Place of Presentation
  長崎
- Year and Date
  2011-02-05
- Data Source
  KAKENHI-PROJECT-20590495
[Presentation] 胸腺皮質および髄質上皮細胞の分化における転写因子Foxnlの役割2011
- Author(s)
  糸井マナミ
- Organizer
  日本胸腺研究会
- Place of Presentation
  長崎、長崎大学医学部良順会館
- Year and Date
  2011-02-05
- Data Source
  KAKENHI-PROJECT-20590495
[Presentation] The role of FoxN1 in the mature epithelial cells and epithelial progenitor cells in the postnatal thymi2010
- Author(s)
  Manami Itoi
- Organizer
  ThymOzVI An International Workshop on T Lymphocytes
- Place of Presentation
  Heron Island, Australia
- Year and Date
  2010-03-19
- Data Source
  KAKENHI-PROJECT-20590495
[Presentation] 胸腺皮質上皮細胞分化と機能発現におけるFoxn1の役割2010
- Author(s)
  糸井マナミ
- Organizer
  第21回京都T細胞カンファレンス
- Place of Presentation
  京都
- Year and Date
  2010-06-10
- Data Source
  KAKENHI-PROJECT-20590495
[Presentation] The role of Foxn1 in the mature epithelial cells and epithelial progenitor cells in the postnatal thymi.2010
- Author(s)
  糸井マナミ
- Organizer
  14^<th> International Congress of Immunology.
- Place of Presentation
  Kobe
- Year and Date
  2010-08-23
- Data Source
  KAKENHI-PROJECT-20590495
[Presentation] Foxnl is differently required for the cortical and medullary epithelial cell development2010
- Author(s)
  Itoi Manami
- Organizer
  The 2^<nd> Synthetic immunology Workshop
- Place of Presentation
  京都、芝蘭会館
- Year and Date
  2010-12-17
- Data Source
  KAKENHI-PROJECT-20590495
[Presentation] Foxn1 is differently required for the cortical and medullary epithelial cell development.2010
- Author(s)
  糸井マナミ
- Organizer
  The 2^<nd> Synthetic immunology Workshop.
- Place of Presentation
  Kyoto
- Year and Date
  2010-12-17
- Data Source
  KAKENHI-PROJECT-20590495
[Presentation] The role of FoxN1 in the mature epithelial cells and epithelial progenitor cells in the postnatal thymi2010
- Author(s)
  Manami Itoi
- Organizer
  Thymoz VI An International Workshop on T lymphocytes
- Place of Presentation
  Gladstone, Australia
- Year and Date
  2010-03-19
- Data Source
  KAKENHI-PROJECT-20060026
[Presentation] The role of Foxn1 in mature epithelial cells and epithelial progenitor cells in the postnatal thymi.2010
- Author(s)
  糸井マナミ
- Organizer
  ThymOzVI : An International Workshop on T Lymphocytes.
- Place of Presentation
  Heron Island. Australia
- Year and Date
  2010-03-19
- Data Source
  KAKENHI-PROJECT-20590495
[Presentation] The role of Foxnl in the mature epithelial cells and epithelial progenitor cells in the postnatal thymi2010
- Author(s)
  Itoi Manami
- Organizer
  14^<th> International Congress of Immunology.
- Place of Presentation
  神戸、神戸ポートピアホテル
- Year and Date
  2010-08-23
- Data Source
  KAKENHI-PROJECT-20590495
[Presentation] Characterization of Foxn1-positive cells in the postnatal mouse thymus2009
- Author(s)
  Manami Itoi
- Organizer
  The 5^<th> International Workshop of Kyoto T Cell Conference
- Place of Presentation
  京都、芝蘭会館
- Year and Date
  2009-06-02
- Data Source
  KAKENHI-PROJECT-20590495
[Presentation] Foxn1 expression in proliferating epithelial cells in the postnatal mouse thymus.2009
- Author(s)
  糸井マナミ
- Organizer
  Proceedings of the Japanese Society for Immunology.
- Place of Presentation
  Osaka
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PROJECT-20590495
[Presentation] Characterization of Foxnl-positive cells in the postnatal Mouse thymus2009
- Author(s)
  Itoi Manami
- Organizer
  KTCC 2009 International workshop on Tlymphocytes
- Place of Presentation
  京都,芝蘭会館
- Year and Date
  2009-06-02
- Data Source
  KAKENHI-PROJECT-20060026
[Presentation] Characterization of Foxn1-positive cells in the postnatal mouse thymus2009
- Author(s)
  Manami Itoi
- Organizer
  The 5^<th> International Workshop of Kyoto T Cell Conference
- Place of Presentation
  芝蘭会館、京都
- Year and Date
  2009-06-02
- Data Source
  KAKENHI-PROJECT-20060026
[Presentation] Foxn1 expression in proliferating epithelial cells in the postnatal mouse thymus2009
- Author(s)
  Manami Itoi
- Organizer
  第39回日本免疫学会
- Place of Presentation
  大阪国際会議場、大阪
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PROJECT-20060026
[Presentation] Characterization of Foxn1-positive cells in the postnatal mouse thymus.2009
- Author(s)
  糸井マナミ
- Organizer
  The 5^<th> International Workshop of Kyoto T Cell Conference.
- Place of Presentation
  Kyoto
- Year and Date
  2009-06-02
- Data Source
  KAKENHI-PROJECT-20590495
[Presentation] Foxn1 expression in proliferating epithelial cells in the postnatal mouse thymus2009
- Author(s)
  Manami Itoi
- Organizer
  第39日本免疫学会
- Place of Presentation
  大阪、大阪国際会議場
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PROJECT-20590495
[Presentation] 胸腺の血管を介するT前駆細胞の胸腺内移動2008
- Author(s)
  Manami Itoi
- Organizer
  The 18^<th> Kyoto T Cell Conference
- Place of Presentation
  京都、芝蘭会館
- Year and Date
  2008-06-14
- Data Source
  KAKENHI-PROJECT-20590495
[Presentation] Lymphocyte-dependent and independent differentiation of cortical epithelial cells2008
- Author(s)
  Itoi Manami
- Organizer
  ThymUS 2008
- Place of Presentation
  San Juan, Puerto Rico
- Year and Date
  2008-11-10
- Data Source
  KAKENHI-PROJECT-20060026
[Presentation] Lymphocyte-dependent and independent differentiation of cortical epithelial cells2008
- Author(s)
  Manami Itoi
- Organizer
  ThymUS 2008
- Place of Presentation
  San Juan, Puerto Rico
- Year and Date
  2008-11-10
- Data Source
  KAKENHI-PROJECT-20590495
[Presentation] 胸腺の血管を介するT前駆細胞の胸腺内移入2008
- Author(s)
  糸井マナミ
- Organizer
  The 18^<th> Kyoto T cell Conference
- Place of Presentation
  京都,芝蘭会館
- Year and Date
  2008-06-14
- Data Source
  KAKENHI-PROJECT-20060026

1. AMAGAI Takashi (80094407)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
2. TSUKAMOTO Noriyuki (80319524)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
3. 武内勇人 (40838132)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 谷川成佑 (00911455)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 萬代綾子 (20769343)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 高橋義信 (90347451)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 岡本貴成 (70814945)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Itoi Manami 糸井 マナミ

ITOI Manami 糸井 マナミ

系井 マナミ イトイ マナミ

ITYOI Manami 糸井 マナミ

Research Projects

Research Products

Co-Researchers

Ferrroptosis in the primary central nervous sytem lymphoma cells amidst tumor microenvironment.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Foxn1陽性胸腺上皮前駆細胞による胸腺の自己形成

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of TEC progenitors and their niche in the adult thymiPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on chemokines and chemokine receptors concerning migration of T-progenitor cells into the thymus anlagen

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Polycomb group gene Bmi1 plays a role in the growth of thymic epithelial cells.2011

Author(s)

Journal Title

Data Source

[Journal Article] Foxn1 is essential for vascularization of the murine thymus anlage.2010

Author(s)

Journal Title

Data Source

[Journal Article] Thymic cysts originate from Foxn1 positive thymic medullary epithelium.2010

Author(s)

Journal Title

Data Source

[Journal Article] Notch activation in thymic epithelial cells induced development of thymic microenvironments.2009

Author(s)

Journal Title

Data Source

[Journal Article] Thymic anlage is colonized by progenitors restricted to T, NK and dendritic cell lineages.2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Thymic anlage is colonized by progenitors restricted to T, NK and dendritic cell lineages.2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Lack of delta like 1 and 4 expressions in nude thymus anlages.2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Polycomb group gene mel-18 regulates early T progenitor expansion by maintaining the expression of Hes-1, a target of the Notch pathway.2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] A role of CXC chemokine ligand 12/stromal cell-derived factor-1/pre-B cell growth stimulating factor and its receptor CXCR4 in fetal and adult T cell development in vivo.2003

Author(s)

Journal Title

Description

Data Source

[Journal Article] Development of thymic microenvironments in vitro is oxygen-dependent and requires permanent presence of T-cell progenitors.2003

Author(s)

Journal Title

Description

Data Source

[Journal Article] A role of CXC chemokine ligand 12/stromal cell-derived factor-1/Pre-B cell growth stimulating factor and its reseptor CXCR4 in fetal and adult T cell development in vivo.2003

Author(s)

Journal Title

Itoi Manami 糸井マナミ

ITOI Manami 糸井マナミ

系井マナミイトイマナミ

ITYOI Manami 糸井マナミ