Hara Hideo 原英夫

… Alternative Names

HARA Hideo 原英夫

原英夫ハラヒデオ

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Researcher Number	00260381
Other IDs
Affiliation (Current)	2025: 福岡国際医療福祉大学, 医療学部, 教授
Affiliation (based on the past Project Information) *help	2022: 佐賀大学, 医学部, 客員研究員 2017 – 2021: 佐賀大学, 医学部, 教授 2012 – 2014: 佐賀大学, 医学部, 教授 2009: 国立長寿医療センター研究所, 血管性認知症研究部, 室長 2005 – 2006: 国立長寿医療センター, (研究所)・血管性認知症研究部, 室長 … More 2001: 国立精神・神経センター, 神経研究所・6部, 室長 2000: 国立精神・神経センター, 神経研究所・疾病研究第6部, 室長 1999: 九大, 医学部, 講師 1998: 九州大学, 医学部, 助手 1998: 九州大学, 医学部, 講師 1995 – 1996: 九州大学, 医学部, 助手 1993: 九州大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Neurology / Neurology / Basic Section 52020:Neurology-related / Immunology Except Principal Investigator Neurology / Biological Sciences / Immunology
Keywords	Principal Investigator HTLV-I / アミロイド血管症 / アルツハイマー型認知症 / アミロイド前駆蛋白遺伝子 / Aβ40/42 / スフェロイド / バイオ3D プリンター / 脳アミロイド血管症 / gag / ICAM1 … More / rolipram / アミロイドベータ蛋白 / アルツハイマー病 / 血液脳関門 / 炎症 / 血管 / 3Dバイオプリンター / アミロイドβ蛋白 / バイオ3Dプリンター / 脳神経疾患 / 細胞内シグナル / ICAM-I / Vβ / TCR / HTLV-1 / 免疫抑制蛋白 / T細胞 / 脳炎症 / サイトカイン / 抗炎症作用 / ワクチン / 老人斑 / 免疫抑制因子 / リンパ球 / 炎症性サイトカイン / 脳炎 / アポトーシス / 遺伝子クローニング / 自己反応性T細胞抑制因子 / アストロサイト / 自己免疫機序 / 多発性硬化症 / Myelin basic protein / T細胞受容体 / PCR in situ hyubridization … More Except Principal Investigator HAM / HTLV-I / TCR / 自己反応性T細胞 / アミロイド / アルツハイマー病 / サイトカイン / Th2バランス / Th1 / AB-DIP / adoplin / aging / neprilysin / glypican 1 / apoptosis / β amyloid / Alzheimer's disease / Alzheimer / LIM / DRAL / APP / PS2 / PS1 / ラフト / グリピカン / β蛋白 / エービーティップ / アドプリン / 老化 / ネプリライシン / グリピカン1 / アポトーシス / βアミロイド / infectious cDNA clone / MT-2 / animal models / Arthritis / Myelopathy / 末梢神経 / 中枢神経 / クローン / ラット / 感染症cDNAクローン / HTLV-1 / キメラ / 感染性cDNAクローン / MT2 / 動物モデル / 関節炎 / 脊髄症 / localization of auto-antigen / autorective T cell / Peptide antigen / Idiotype / soluble single Fv TCR / T cell hybridoma / T細胞抗原受容体遺伝子 / 自己免疫病 / 自己抗原 / 抗原提示細胞 / 可溶性T細胞抗原受容体 / 自己抗原の組織内局在 / ペプチド抗原 / イディオタイプ / 可溶性TCR分子 / T細胞ハイブリドーマ / epitope spreading / HLA-class II / autoreactive T cell / myelin protein / opticospinal / multiple sclerosis / 脊髄 / Myelin oligodendrocyte glycoprotein / Proteolipid protein / Myelin basic protein / T細胞 / 髄鞘 / HLA / エピトープの拡大 / HLAクラスII / ミエリン蛋白 / 視神経脊髄型 / 多発性硬化症 / 老人班 / 老人斑 / amyloid / 免疫 / 十全大補湯 / モノクローナル抗体 / ミクログリア / 漢方薬 / ワクチン / リンパ球サブセット / CD8陽性T細胞 / アトピー / ダニ / 脊髄炎 Less

Bio-fabrication of cerebral amyloid angiopathy model using Bio-3D printer and analysis of the pathophysiological mechanisms.Principal Investigator
- Principal Investigator
  
  Hara Hideo
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Saga University
Bio-fabrication of cerebral amyloid angiopathy model using Bio-3D printer and analysis of the pathophysiological mechanisms.Principal Investigator
- Principal Investigator
  
  Hara Hideo
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Saga University
Analysis of chronic inflammation in the Alzheimer's brain and development of the treatment for the suppression of T cell activation.Principal Investigator
- Principal Investigator
  
  HARA Hideo
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Saga University
Analysis of immune mechanisms of Alzheimer's disease and development of a novel treatment
- Principal Investigator
  
  TABIRA Takeshi
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Juntendo University
  National Institute for Longevity Sciences,NCGG
Identification of aging-related factors that facilitate Alzheimer's disease
- Principal Investigator
  
  TABIRA Takeshi
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  NATIONAL INSTITUTE FOR LONGEVITY SCIENCES
  National Center of Neurology and Psychiatry
アストロサイト由来の自己反応性T細胞抑制因子の解明と遺伝子クローニングPrincipal Investigator
- Principal Investigator
  
  原英夫
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kyushu University
ダニ抗原特異的なアトピーを特徴とする脊髄炎におけるTh2タイプT細胞応答の解析
- Principal Investigator
  
  吉良潤一
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Neurology
- Research Institution
  Kyushu University
Establishment of a polyreactive T cell clone from Asian type multiple sclerosis patients and identification of the responsible antigens
- Principal Investigator
  
  KIRA Jun-ichi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  KYUSHU UNIVERSITY
Regulation of T cell activity and detection of TCR-binding antigen by recombinant soluble TCR molecules
- Principal Investigator
  
  WATANABE Takeshi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  Kyushu University
Induction of chronic inflammatory myelopathy in rats infected with recombinant HTLV-I
- Principal Investigator
  
  KIRA Jun-ichi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  KYUSHU UNIVERSITY
Analysis of the pathomechanism of the demyelinating diseases and the searach for the therapyPrincipal Investigator
- Principal Investigator
  
  HARA Hideo
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  KYUSHU UNIVERISTY
HTLV-I関連脊髄症におけるT細胞抗原受容体と抗原の解析Principal Investigator
- Principal Investigator
  
  原英夫
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Neurology
- Research Institution
  Kyushu University

[Book] Innovations in nephrology.3D printers in nephrology2022
- Author(s)
  Toshihiro Nonaka, Yukiko Nagaishi, Daiki Murata, Hideo Hara, Koichi Nakayama
- Total Pages
  16
- Publisher
  Springer
- ISBN
  9783031115707
- Data Source
  KAKENHI-PROJECT-20K07890
[Book] 脳卒中エキスパート：降圧療法を究める。2020
- Author(s)
  藥師寺祐介、原英夫
- Total Pages
  13
- Publisher
  中外医学社
- ISBN
  9784498328624
- Data Source
  KAKENHI-PROJECT-20K07890
[Book] 認知症ハンドブック第4章認知症の危険因子と予防. 1 認知症と危険因子の関係. A. 高血圧と認知症の関係2020
- Author(s)
  藥師寺祐介、原英夫
- Total Pages
  10
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-20K07890
[Book] アルツハイマー病、今日の治療指針20182018
- Author(s)
  原　英夫(分担執筆)
- Total Pages
  2066
- Publisher
  医学書院
- ISBN
  9784260032339
- Data Source
  KAKENHI-PROJECT-17K09758
[Book] 今日の治療指針2018, アルツハイマー病2018
- Author(s)
  原　英夫
- Total Pages
  2066
- Publisher
  医学書院
- ISBN
  9784260032339
- Data Source
  KAKENHI-PROJECT-17K09758
[Book] 認知症の予防2017
- Author(s)
  原　英夫
- Total Pages
  133
- Publisher
  ライフ・サイエンス
- ISBN
  9784898015933
- Data Source
  KAKENHI-PROJECT-17K09758
[Book] 認知症疾患診療ガイドライン20172017
- Author(s)
  原　英夫
- Total Pages
  362
- Publisher
  医学書院
- ISBN
  9784260028585
- Data Source
  KAKENHI-PROJECT-17K09758
[Book] 神経内科研修ノート2015
- Author(s)
  原英夫
- Total Pages
  695
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-24591266
[Book] ABC22 アルツハイマー病改訂第2版2014
- Author(s)
  原英夫
- Total Pages
  224
- Publisher
  最新医学社
- Data Source
  KAKENHI-PROJECT-24591266
[Book] 今日の神経疾患治療指針 2013；神経ボレリア症（ライム病）2013
- Author(s)
  原英夫
- Total Pages
  11
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-24591266
[Book] Neuroviral infection, Human T-lymphotropic virus2013
- Author(s)
  Yukitake M, Hara H
- Total Pages
  455
- Publisher
  Taylor & Francis group
- Data Source
  KAKENHI-PROJECT-24591266
[Book] 今日の神経疾患治療指針-神経ボレリア症（ライム病）2013
- Author(s)
  原英夫
- Total Pages
  1100
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-24591266
[Book] 内科学第9版；髄膜炎、脳炎2013
- Author(s)
  原英夫
- Total Pages
  4
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-24591266
[Book] Neuroviral Infections.;Human T-lymphotropic virus. Neuroviral infection2013
- Author(s)
  Yukitake M, Hara H
- Total Pages
  25
- Publisher
  Taylor & Francis group
- Data Source
  KAKENHI-PROJECT-24591266
[Book] 多発性硬化症の鑑別診断、多発性硬化症と視神経脊髄炎2012
- Author(s)
  原英夫
- Total Pages
  409
- Publisher
  中山書店
- Data Source
  KAKENHI-PROJECT-24591266
[Journal Article] Hypertension, cerebral Amyloid, aGe Associated Known neuroimaging markers of cerebral small vessel disease Undertaken with stroke REgistry (HAGAKURE) prospective cohort study: Baseline characteristics and association of cerebral small vessel disease with prognosis in an ischemic stroke cohort2023
- Author(s)
  Ikeda Shuhei、Yakushiji Yusuke、Tanaka Jun、et al.
- Journal Title
  
  Frontiers in Aging Neuroscience
  
  Volume: 15 Pages: 01-09
- DOI
  10.3389/fnagi.2023.1117851
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K10510, KAKENHI-PROJECT-20K07890, KAKENHI-PROJECT-20K17935, KAKENHI-PROJECT-21K09101
[Journal Article] Harboring Cnm‐expressing <i>Streptococcus mutans</i> in the oral cavity relates to both deep and lobar cerebral microbleeds2023
- Author(s)
  Ikeda Shuhei、Saito Satoshi...
- Journal Title
  
  European Journal of Neurology
  
  Volume: - Issue: 11 Pages: 3487-3496
- DOI
  10.1111/ene.15720
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K16944, KAKENHI-PROJECT-21H03149, KAKENHI-PROJECT-20K07890, KAKENHI-PROJECT-21K16961, KAKENHI-PROJECT-20H04047
[Journal Article] Immune dysregulation syndrome with cytotoxic T-lymphocyte antigen 4 mutation showing multiple central nervous system lesions.2022
- Author(s)
  M Eriguchi, H Katsuya, K Kidoguchi, H Ureshino, M Nishi, M Nishihara, M Sonoda, M Ishimura, S Kimura, H Hara.
- Journal Title
  
  Clin Exp Neuroimmunol
  
  Volume: 13 Issue: 2 Pages: 116-120
- DOI
  10.1111/cen3.12672
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07890
[Journal Article] Olfactory-cognitive index distinguishes involvement of frontal lobe shrinkage, as in sarcopenia from shrinkage of medial temporal areas, and global brain, as in Kihon Checklist frailty/dependence, in older adults with progression of normal cognition to Alzheimer's disease.2021
- Author(s)
  Iritani O, Okuno T, Miwa T, Makizako H, Okutani F, Kashibayashi T, Suzuki K, Hara H, Mori E, Omoto S, Suzuki H, Shibata M, Adachi H, Kondo K, Umeda-Kameyama Y, Kodera K, Morimoto S.
- Journal Title
  
  Geriatr Gerontol Int
  
  Volume: 21 Issue: 3 Pages: 291-298
- DOI
  10.1111/ggi.14128
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11219, KAKENHI-PROJECT-20K07849, KAKENHI-PROJECT-19K07970, KAKENHI-PROJECT-20K07890, KAKENHI-PROJECT-21H03090
[Journal Article] Intracranial M?nckeberg’s Atherosclerosis Is Frequently Found in Autopsy Cases of Advanced Stage Malignancy with Cerebral Infarction2021
- Author(s)
  Shichijo Chika、Kai Keita、Jinnouchi Kazuki、Nishihara Masashi、Hara Hideo、Aishima Shinichi
- Journal Title
  
  Cancers
  
  Volume: 13 Issue: 20 Pages: 5234-5234
- DOI
  10.3390/cancers13205234
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07408, KAKENHI-PROJECT-20K07890
[Journal Article] Genome wide association study of HTLV-1 associated myelopathy/tropical spastic paraparesis in the Japanese population2021
- Author(s)
  Penova Marina et al.
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 118 Issue: 11
- DOI
  10.1073/pnas.2004199118
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07349, KAKENHI-PROJECT-19K07983, KAKENHI-PROJECT-19H03689, KAKENHI-PROJECT-19H03575, KAKENHI-PROJECT-18K07541, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-20K22879, KAKENHI-PROJECT-20H03514, KAKENHI-PROJECT-20K07890, KAKENHI-PROJECT-16K18474
[Journal Article] Meta-iodobenzylguanidine myocardial scintigraphy in Perry disease2021
- Author(s)
  Mishima T, Fujioka S, Nishioka K, Li Y, Sato K, Houzen H, Yabe I, Shiomi K, Eriguchi M, Hara H, Hattori N, Tsuboi Y.
- Journal Title
  
  Parkinsonism and related disorders
  
  Volume: In press Pages: 49-53
- DOI
  10.1016/j.parkreldis.2020.12.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07893, KAKENHI-PROJECT-18K15471, KAKENHI-PROJECT-20K07890
[Journal Article] Multiple cerebral infarctions in the deep perforator regions in a case of idiopathic hypereosinophilic syndrome2021
- Author(s)
  飯田紘太郎、薬師寺祐介、井手俊宏、鶴岡ななえ、七條千佳、原英夫
- Journal Title
  
  Rinsho Shinkeigaku
  
  Volume: 61 Issue: 5 Pages: 319-324
- DOI
  10.5692/clinicalneurol.cn-001561
- NAID
  130008039483
- ISSN
  0009-918X, 1882-0654
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07890
[Journal Article] 認知症2021
- Author(s)
  原英夫
- Journal Title
  
  臨床と研究
  
  Volume: 98 Pages: 62-67
- Data Source
  KAKENHI-PROJECT-20K07890
[Journal Article] Nasal vaccine delivery attenuates brain pathology and cognitive impairment in tauopathy model mice2020
- Author(s)
  Takeuchi Hiroki、Imamura Keiko、Ji Bin、Tsukita Kayoko、Enami Takako、Takao Keizo、Miyakawa Tsuyoshi、Hasegawa Masato、Sahara Naruhiko、Iwata Nobuhisa、Inoue Makoto、Hara Hideo、Tabira Takeshi、Ono Maiko、Trojanowski John Q.、Lee Virginia M.-Y.、Takahashi Ryosuke、Suhara Tetsuya、Higuchi Makoto、Inoue Haruhisa
- Journal Title
  
  npj Vaccines
  
  Volume: 5 Issue: 1 Pages: 28-28
- DOI
  10.1038/s41541-020-0172-y
- NAID
  120006817588
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05213, KAKENHI-PUBLICLY-19H05010, KAKENHI-PROJECT-19H03538, KAKENHI-PROJECT-17K10297, KAKENHI-PROJECT-19K06896, KAKENHI-PUBLICLY-19H05437, KAKENHI-PROJECT-20K07890
[Journal Article] Total small vessel disease score and cerebro-cardiovascular events in healthy adults: the Kashima Scan Study.2020
- Author(s)
  Kohei Suzuyama, Yusuke Yakushiji, Atsushi Ogata, Masashi Nishihara, Makoto Eriguchi, Atsushi Kawaguchi, Tomoyuki Noguchi, Junko Nakajima, Hideo Hara
- Journal Title
  
  International Journal of Stroke
  
  Volume: - Issue: 9 Pages: 973-979
- DOI
  10.1177/1747493020908144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09758, KAKENHI-PROJECT-20K07890
[Journal Article] Distribution of cerebral microbleeds in the East and West2019
- Author(s)
  Yakushiji Yusuke、Wilson Duncan、Ambler Gareth、et al.
- Journal Title
  
  Neurology
  
  Volume: 92 Issue: 10 Pages: 1086-1097
- DOI
  10.1212/wnl.0000000000007039
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10364, KAKENHI-PROJECT-17K09758, KAKENHI-PROJECT-16K15419
[Journal Article] 認知症を予防する。２．危険因子；喫煙と認知症2019
- Author(s)
  原英夫
- Journal Title
  
  Geriatric Medicine
  
  Volume: 57 Pages: 355-356
- Data Source
  KAKENHI-PROJECT-17K09758
[Journal Article] 認知症リスクとしての脳微小出血（マイクロブリーズ）2019
- Author(s)
  薬師寺祐介、原英夫
- Journal Title
  
  最新医学
  
  Volume: 74 Pages: 86-93
- Data Source
  KAKENHI-PROJECT-17K09758
[Journal Article] 脳ドックにおける読影：臨床編　２）Micro Bleeds2019
- Author(s)
  星野有紀、薬師寺祐介、原英夫
- Journal Title
  
  脳神経外科速報
  
  Volume: 29 Pages: 720-724
- Data Source
  KAKENHI-PROJECT-17K09758
[Journal Article] Synergistic effect of hypertension and smoking on the total small vessel disease score in healthy individuals: the Kashima scan study.2019
- Author(s)
  M Hara, Y Yakushiji, K Suzuyama, M Nishihara, M Eriguchi, T Noguchi, M Nishiyama, Y Nanri, J Tanaka, H Hara.
- Journal Title
  
  Hypertension Research
  
  Volume: 42 Issue: 11 Pages: 1738-1744
- DOI
  10.1038/s41440-019-0282-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09758
[Journal Article] 脳卒中専門医のための画像診断：Cortical superficial siderosis.2018
- Author(s)
  吉川正章、薬師寺祐介、原英夫
- Journal Title
  
  分子脳血管病
  
  Volume: 17 Pages: 71-75
- Data Source
  KAKENHI-PROJECT-17K09758
[Journal Article] Total Small Vessel Disease Score in Neurologically Healthy Japanese Adults in the Kashima Scan Study2018
- Author(s)
  Yakushiji Y, Charidimou A, Noguchi T, Nishihara M, Eriguchi M, Nanri Y, Kawaguchi A Hirotsu T, Werring DJ, Hara H
- Journal Title
  
  Intern. Med.
  
  Volume: 57 Issue: 2 Pages: 189-196
- DOI
  10.2169/internalmedicine.8393-16
- NAID
  130006309177
- ISSN
  0918-2918, 1349-7235
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10364, KAKENHI-PROJECT-16K10333, KAKENHI-PROJECT-17K09758
[Journal Article] アルツハイマー型認知症の病態修飾治療の今後2018
- Author(s)
  原英夫
- Journal Title
  
  臨床と研究
  
  Volume: 95 Pages: 57-61
- Data Source
  KAKENHI-PROJECT-17K09758
[Journal Article] アルツハイマー型認知症の最新の治療とケア2017
- Author(s)
  原英夫
- Journal Title
  
  日本内科学会雑誌
  
  Volume: 106 Pages: 1991-1995
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09758
[Journal Article] Cerebral microbleeds例での一次予防・二次予防2017
- Author(s)
  鈴山耕平、藥師寺祐介, 原英夫
- Journal Title
  
  脳梗塞と心房細動
  
  Volume: 4 Pages: 9-13
- Data Source
  KAKENHI-PROJECT-17K09758
[Journal Article] Successful resolution of mobile thrombus in internal carotid artery with dabigatran and aspirin in an atherothrombotic cerebral infarction patient with non-valvular atrial fibrillation2017
- Author(s)
  上床希久，藥師寺祐介，井手俊宏，田畑絵美，吉川正章，原英夫
- Journal Title
  
  Japanese Journal of Stroke
  
  Volume: 39 Issue: 4 Pages: 277-281
- DOI
  10.3995/jstroke.10448
- NAID
  130005858953
- ISSN
  0912-0726, 1883-1923
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10364, KAKENHI-PROJECT-17K09758
[Journal Article] A case of dabigatran-induced esophagitis improved rapidly after switching medication from dabigatran to apixaban2017
- Author(s)
  永石友公子,　藥師寺祐介,　下田良,　増田正憲,　原英夫
- Journal Title
  
  Japanese Journal of Stroke
  
  Volume: 39 Issue: 4 Pages: 304-308
- DOI
  10.3995/jstroke.10459
- NAID
  130005858944
- ISSN
  0912-0726, 1883-1923
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10364, KAKENHI-PROJECT-17K09758
[Journal Article] Thrombolysis-related Multiple Lobar Hemorrhaging in Cerebral Amyloid Angiopathy with Extensive Strictly Lobar Cerebral Microbleeding2017
- Author(s)
  Eriguchi M, Yakushiji Y, Tanaka J, Nishihara M, Hara H
- Journal Title
  
  Intern. Med.
  
  Volume: 56 Issue: 14 Pages: 1907-1910
- DOI
  10.2169/internalmedicine.56.8007
- NAID
  130005773807
- ISSN
  0918-2918, 1349-7235
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10364, KAKENHI-PROJECT-17K09758
[Journal Article] Norms of the Mini-Mental State Examination for Japanese Subjects that Underwent Comprehensive Brian Examinations: The Kashima Scan Study2014
- Author(s)
  Yakushiji Y, Horikawa E, Eriguchi M, Nanri Y, Nishihara M, Hirotsu T, Hara H.
- Journal Title
  
  Intern. Med.
  
  Volume: 53 Issue: 21 Pages: 2447-2453
- DOI
  10.2169/internalmedicine.53.2683
- NAID
  130004704952
- ISSN
  0918-2918, 1349-7235
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591266
[Journal Article] Topography and associations of perivascular spaces in healthy adults: the Kashima scan study.2014
- Author(s)
  Yakushiji Y, Charidimou A, Hara M, Noguchi T, Nishihara M, Eriguchi M, Nanri Y, Nishiyama M, Werring DJ, Hara H.
- Journal Title
  
  Neurology
  
  Volume: 83 Issue: 23 Pages: 2116-2123
- DOI
  10.1212/wnl.0000000000001054
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591266
[Journal Article] 根本的治療；今までの軌跡と未来への展望2014
- Author(s)
  原英夫
- Journal Title
  
  認知神経科学
  
  Volume: 16 Pages: 61-66
- NAID
  130006895785
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591266
[Journal Article] Basal Ganglia Cerebral Microbleeds and Global Cognitive Function: The Kashima Scan Study.2014
- Author(s)
  Yakushiji Y, Noguchi T, Charidimou A, Eriguchi M, Nishihara M, Hara M, Nanri Y, Horikawa E, Nishiyama M, Werring DJ, Hara H.
- Journal Title
  
  J Stroke Cerebrovasc Dis.
  
  Volume: 24 Issue: 2 Pages: 431-439
- DOI
  10.1016/j.jstrokecerebrovasdis.2014.09.015
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591266, KAKENHI-PROJECT-24591774
[Journal Article] Alzheimer病の免疫治療-最近の動向―2014
- Author(s)
  原英夫
- Journal Title
  
  神経内科
  
  Volume: 80 Pages: 371-375
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591266
[Journal Article] Immunopathological significance of ovarian teratoma in patients with anti-N-methyl-D-aspartate receptor encephalitis2014
- Author(s)
  Tabata, E. Masuda, M. Eriguchi, M. Yokoyama, M. Takahashi, Y. Tanaka, K. Yukitake, M, Horikawa, E. Hara, H
- Journal Title
  
  Eur Neurol
  
  Volume: 71 Issue: 1-2 Pages: 42-48
- DOI
  10.1159/000353982
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500455, KAKENHI-PROJECT-24591266
[Journal Article] Stroke scale items associated with neurologic deterioration within 24 hours after recombinant tissue plasminogenn activator therapy.2013
- Author(s)
  Nanri Y, Yakushiji Y, Hara M, Eriguchi M, Okada R, Yukitake M, Hara H.
- Journal Title
  
  J. Stroke and Cardiovas dises.
  
  Volume: 22 Issue: 7 Pages: 1117-1124
- DOI
  10.1016/j.jstrokecerebrovasdis.2012.10.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591266
[Journal Article] 止血剤の点滴および内服加療で改善をみとめた脳表ヘモジデリン沈着症の1例2013
- Author(s)
  南里悠介、薬師寺祐介、雪竹基弘、中原由紀子、松島敏夫、原英夫
- Journal Title
  
  臨床神経学
  
  Volume: 53 Pages: 470-473
- NAID
  130004505523
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591266
[Journal Article] 手掌・両側口症候群を呈した片側橋被蓋傍正中部出血の1例2013
- Author(s)
  山口りか、南里悠介、薬師寺祐介、雪竹基弘、原英夫
- Journal Title
  
  臨床神経学
  
  Volume: 53 Pages: 46-49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591266
[Journal Article] Joint effect of hypertension and lifestyle-related risk factors on the risk of brain microbleeds in healthy individuals2013
- Author(s)
  Hara M, Yakushiji Y, Nannri H, Sasaki S, Noguchi T, Nishiyama M, Hirotsu T, Nakajima J, Hara H
- Journal Title
  
  Hypertens Res
  
  Volume: 36 Issue: 9 Pages: 789-794
- DOI
  10.1038/hr.2013.26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890157, KAKENHI-PROJECT-24591266, KAKENHI-PROJECT-24591774
[Journal Article] 経皮的カテーテル心房中隔欠損孔閉鎖術により前兆のある片頭痛が消失した1例2013
- Author(s)
  田中　淳、薬師寺祐介、南里悠介、梶原正貴、須田憲治、原　英夫
- Journal Title
  
  臨床神経学
  
  Volume: 53 Pages: 638-641
- NAID
  130004505541
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591266
[Journal Article] Refractory acute disseminated encephalopathy with anti-galactocerebroside antibody.2013
- Author(s)
  Samukawa M, Hirano M, Tsugawa J, Sakamoto H, Tabata E, Takada K, Kuwahara M, Suzuki S, Kitada M, Yamada T, Hara H, Tsuboi Y, Nakamura Y, Kusunoki S.
- Journal Title
  
  Neuroscience Research
  
  Volume: 74 Issue: 3-4 Pages: 284-289
- DOI
  10.1016/j.neures.2012.09.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591266
[Journal Article] Distributional impact of brain microbleeds on global cognitive function in adults without neurological disorder.2012
- Author(s)
  Yakushiji Y, Noguchi T, Hara M, Nishihara M, Eriguchi M, Nanri Y, Nishiyama M, Hirotsu T, Nakajima J, Kuroda Y, Hara.H.
- Journal Title
  
  Stroke
  
  Volume: 43 Pages: 1800-1805
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591266
[Journal Article] Simultaneous angiography and ultrasonography in extracranial internal carotid artery dissection.2012
- Author(s)
  Oka T, Yakushiji Y, Nanri Y, Takase Y, Hara H.
- Journal Title
  
  Neurology
  
  Volume: 78 Pages: 150-150
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591266
[Journal Article] Stroke scale items associated with neurologic deterioration within 24 hours after recombinant tissue plasminogenn activator therapy.2012
- Author(s)
  Nanri Y, Yakushiji Y, Hara M, Eriguchi M, Okada R, Yukitake M, Hara H.
- Journal Title
  
  J. Stroke and Cardiovas dises.
  
  Volume: in press Pages: 1-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591266
[Journal Article] The therapeutic effects of herbal medicine, Juzen-taiho-to on the reduction of Aβ burden in a mouse model of Alzheimer's disease.2010
- Author(s)
  Hara H, Kataoka S, Anan M, Ueda A, Mutoh T, Tabira T
- Journal Title
  
  (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17025056
[Journal Article] The therapeutic effects of herbal medicine, Juzen-taiho-to on the reduction of A・burden in a mouse model of Alzheimer's disease2010
- Author(s)
  Hara H, Kataoka S, Anan M, Ueda A, Mutoh T, Tabira T.
- Journal Title
  
  J Alzheim (in press)
- Data Source
  KAKENHI-PROJECT-17025056
[Journal Article] Development and characterization of a TAPIR-like mouse monoclonal antibody to Aβ2008
- Author(s)
  Wang, J., Hara, H., Makifuchi, T., Tabira, T.
- Journal Title
  
  J Alzheim Dis 14
  
  Pages: 161-73
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17025056
[Journal Article] Developmentand characterization of a TAPIR-like mouse monoclonal antibody to Aβ2008
- Author(s)
  Wang, J., Hara, H., Makifuchi, T., TabiT.
- Journal Title
  
  J Alzheim Dis 14
  
  Pages: 161-73
- Data Source
  KAKENHI-PROJECT-17025056
[Journal Article] Amyloid beta protein-related death-Inducing Protein Induces G2/M arrest: Implications for neurodegeneration in Alzheimer's diseasa.2007
- Author(s)
  Lakshmana, M. K., Hara, H. & Tabira, T.
- Journal Title
  
  J. Neurosci. Res. 85
  
  Pages: 2262-71
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17025056
[Journal Article] Oral vaccination with a recombinant adeno-associated viral vector attenuates age-related Abeta accumulation and memory deficits without lymphocytic infiltration in Tg2576 mice2007
- Author(s)
  Mouri, A., Noda, Y., Hara, H., Mizoguchi, H., Tabira, T., Nabeshima, T.
- Journal Title
  
  FASEB J. 21
  
  Pages: 2135-48
- Data Source
  KAKENHI-PROJECT-17025056
[Journal Article] Oral vaccination with a recombinant adeno-associated viral vector attenuates age-related Abeta accumulation and memory deficits without lymphocytic infiltration in Tg2576 mice.2007
- Author(s)
  Mouri A, Noda Y, Hara H, Mizoguchi S, Tabira T, Nabeshima T
- Journal Title
  
  FASEB J
- Data Source
  KAKENHI-PROJECT-17025056
[Journal Article] Molecular chaperone inducer protects neurons from ER stress2007
- Author(s)
  Kudo, T., Kanemoto, s., Hara, H., Morimoto, N., Morihara, T., Kimura, R., Tabira, T., Imaizumi, K. & Takeda M. A.
- Journal Title
  
  Cell Death Differentiation 30
  
  Pages: 1-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17025056
[Journal Article] Altered localization of amyloid precursor protein under endoplasmic reticulum stress.2006
- Author(s)
  Kudo T, Okumura M, Imaizumi K, Araki W, Morihara T, Tanimukai H, Kamagata E, Tabuchi N, Kimura R, Kanayama D, Fukumori A, Tagami S, Okochi M, Kubo M, Tanii H, Tohyama M, Tabira T, Takeda M
- Journal Title
  
  Biocnem Biopnys Res Commun 344
  
  Pages: 525-530
- Data Source
  KAKENHI-PROJECT-17025056
[Journal Article] Mechanism of natural killer (NK) cell regulatory role in experimental autoimmune encephalomvelitis.2005
- Author(s)
  Xu W, Fazekas G, Hara H, Tabira T.
- Journal Title
  
  J Neuroimmunol. 163
  
  Pages: 24-30
- Data Source
  KAKENHI-PROJECT-17025056
[Journal Article] Abnormal intracellular trafficking of high affinity nerve growth factor receptor, Trk. stable transfectants expressing presenilin 1 protein.2005
- Author(s)
  Hamano T, Mutoh T, Tabira T, Araki W, Kuriyama M, Mihara T, Yano S, Yamamoto H.
- Journal Title
  
  Brain Res Mol Brain Res. 137
  
  Pages: 70-76
- Data Source
  KAKENHI-PROJECT-17025056
[Journal Article] Development of a safe oral Abeta vaccine using recombinant adeno-associated virus vector for Alzheimer's disease.2004
- Author(s)
  Hara H, Monsonego A, Yuasa K, Adachi K, Xiao X, Takeda S, Takahashi K, Weiner HL, Tabira T.
- Journal Title
  
  J Alzheim Dis 6
  
  Pages: 483-488
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12210021
[Journal Article] Intracellular Abeta42 activates p53 promoter : a pathway to neurodegeneration in Alzheimer's disease.2004
- Author(s)
  Ohyagi Y, Asahara H, Chui DH, Tsuruta Y, Sakae N, Miyoshi K, Yamada T, Kikuchi H, Taniwaki T, Murai H, Ikezoe K, Furuya H, Kawarabayashi T, Shoji M, Checler F, Iwaki T, Makifuchi T, Takeda K, Kira JI, Tabira T.
- Journal Title
  
  FASEB J 19
  
  Pages: 255-257
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12210021
[Journal Article] Glypican-1 as an Aβ binding HSPG in the human brain : its localization in DIG domains and possible roles in the pathogenesis of Alzheimer's disease.2004
- Author(s)
  Watanabe N, Araki W, Chui DH, Makibuchi T, Ihara Y, Tabira T.
- Journal Title
  
  FASEB J 18
  
  Pages: 1013-1015
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12210021
[Journal Article] Glypican-1 as an Aβ binding HSPG in the human brain : its localization in DIG domains and possible roles in the pathogens is of Alzheimer's disease.2004
- Author(s)
  Watanabe N, Araki W, Chui DH, Makibuchi T, Ihara Y, Tabira T.
- Journal Title
  
  FASEB J 18
  
  Pages: 1013-1015
- Data Source
  KAKENHI-PROJECT-12210021
[Journal Article] Development of a safe oral Abeta vaccine using recombinant adeno-associated virus vector for Alzheimer's disease.2004
- Author(s)
  Hara H, Monsonego A, Yuasa K, Adachi K, Xiao X, Takeda S, Takahashi K, Weiner HL, Tabira T
- Journal Title
  
  J Alzheim Dis 6
  
  Pages: 483-488
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12210021
[Journal Article] Glypican-1 as an Aβ binding HSPG in the human brain : its localization in DIG domains and possible roles in the pathogens is of Alzheimer's disease.2004
- Author(s)
  Watanabe N, Araki W, Chui DH, Makibuchi T, Ihara Y, Tabira T
- Journal Title
  
  FASEB J 18
  
  Pages: 1013-1015
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12210021
[Journal Article] Intracellular Abeta42 activates p53 promoter : a pathway to neurodegeneration in Alzheimer's disease.2004
- Author(s)
  Ohyagi Y, Asahara H, Chui DH, Tsuruta Y, Sakae N, Miyoshi K, Yamada T, Kikuchi H, Taniwaki T, Murai H, Ikezoe K, Furuya H, Kawarabayashi T, Shoji M, Checler F, Iwaki T, Makifuchi T, Takeda K, Kira JI, Tabira T
- Journal Title
  
  FASEB J 19
  
  Pages: 255-257
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12210021
[Journal Article] Development and characterization of a TAPIR-like mouse monoclonal antibody to Aβ
- Author(s)
  Wang, J., Hara, H., Makifuchi, T. & Tabira, T.
- Journal Title
  
  J.Alzheim. in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17025056
[Patent] アルツハイマー病治療のための組換アデノ随伴ウイルスベクター2004
- Inventor(s)
  田平武, 原英夫
- Industrial Property Rights Holder
  国立長寿医療センター, 医薬品被害救済調査審議機構
- Filing Date
  2004-06-11
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12210021
[Patent] アルツハイマー病治療のための組換アデノ随伴ウイルスベクター2003
- Inventor(s)
  田平武, 原英夫
- Industrial Property Rights Holder
  国立療養所中部病院太田壽城, 医薬品被害救済調査審議機構
- Filing Date
  2003-06-13
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12210021
[Presentation] バイオ３Dプリンターで作製した足場材を用いない動脈硬化症実験モデルの開発2022
- Author(s)
  西久保友公子、村田　大紀、伊藤　学、原　英夫、中山　功一
- Organizer
  第22回日本再生医療学会
- Data Source
  KAKENHI-PROJECT-20K07890
[Presentation] アルツハイマー型認知症の病態修飾薬の展望2022
- Author(s)
  原英夫
- Organizer
  第72回日本内科学会九州支部生涯教育講演会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07890
[Presentation] 第40回日本認知症学会学術集会　専門医試験対策講座アルツハイマー病と症候学2021
- Author(s)
  原英夫
- Organizer
  第40回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07890
[Presentation] 脳アミロイドアンギオパチー関連脳出血臨床診断におけるBoston基準とEdinburgh基準の相違：HAGAKURE study2020
- Author(s)
  吉川正章、藥師寺祐介、緒方敦之、西原正志、小野翔平、井手俊宏、鈴山耕平、江里口誠、原英夫
- Organizer
  STROKE 2020
- Data Source
  KAKENHI-PROJECT-20K07890
[Presentation] Total Small Vessel Disease Score among Ischemic Stroke Subtypes: HAGAKURE study.2020
- Author(s)
  Iida K, Yakushiji Y, Tanaka J,Nishihara M, Eriguchi M, Suzuyama K, Shichijo C, Nagaishi Y, Megumi M, Suetsugu N, Ide T, Yoshikawa M, Hoshino Y, Katsuki Y, Hideo H
- Organizer
  European stroke organisation - World stroke organization (ESO-WSO)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07890
[Presentation] Subclinical acute Ischemic lesions and cerebrospinal fluid profiles in intracerebral hemorrhage: HAGAKURE STUDY.2020
- Author(s)
  Yoshikawa M, Yakushiji Y, Tanaka J, Ogata A, Nishihara M, Eriguchi M, Suzuyama K, Nagaishi Y, Mizoguchi M, Shichijo C, Ide T, Katsuki Y, Kawamoto K, Abe T, Hara H
- Organizer
  European stroke organisation - World stroke organization
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07890
[Presentation] Extending the clinical spectrum of cerebral amyloid angiopathy (CAA): Clinical spectrum of CAA-related cerebrovascular disorders.2019
- Author(s)
  Yakushiji Y, Hara H
- Organizer
  日本神経学学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09758
[Presentation] 約30年前の開頭血腫除去術後に左後頭葉の皮質下出血を発症した脳アミロイドアンギオパチーの一例2019
- Author(s)
  星野有紀、井手俊宏、江里口誠、薬師寺祐介、原英夫
- Organizer
  日本神経学会九州地方会
- Data Source
  KAKENHI-PROJECT-17K09758
[Presentation] シンポジウム5　「認知症と脳小血管病のクロストーク」: 脳微小出血と認知症2019
- Author(s)
  藥師寺祐介、美奈川拡、吉川正章、原英夫
- Organizer
  日本脳ドック学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09758
[Presentation] 脳出血関連病変の頻度の検討 The Kashima Scan Study2019
- Author(s)
  吉川正章、薬師寺祐介、西原正志、小杉雅史、原英夫
- Organizer
  脳卒中学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09758
[Presentation] シンポジウム12　「脳小血管病のクロストーク」: 脳微小出血の病理学的分布様式の人種差2019
- Author(s)
  藥師寺祐介, 星野有紀，美奈川拡，吉川正章，井手俊宏, 原英夫
- Organizer
  日本認知症学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09758
[Presentation] 脳血管病と認知症：微小脳出血と認知機能障害 - update-2019
- Author(s)
  藥師寺祐介, 鈴山耕平, 美奈川拡, 吉川正章, 星野有紀, 原英夫
- Organizer
  日本脳卒中学会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09758
[Presentation] 特発性正常圧水頭症と脳出血患者における髄液バイオマーカーの検討2018
- Author(s)
  鈴山耕平，薬師寺祐介，西原正志，江里口誠，野口智幸，田中淳，原英夫
- Organizer
  第27回日本脳ドック学会
- Data Source
  KAKENHI-PROJECT-17K09758
[Presentation] 学術教育講演；感染症と認知症2018
- Author(s)
  原英夫
- Organizer
  第37回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09758
[Presentation] 繰り返すTransient focal neurological episodeの発症後早期に皮質下出血を発症した脳アミロイドアンギオパチーの一例.2018
- Author(s)
  吉川正章, 鈴山耕平, 藥師寺祐介, 原英夫
- Organizer
  第223回　日本神経学会九州地方会
- Data Source
  KAKENHI-PROJECT-17K09758
[Presentation] 高血圧とライフスタイル関連因子の相乗効果とSmall Vessel Diseaseの関連 -the Kashima scan study -2018
- Author(s)
  薬師寺祐介，原めぐみ, 鈴山耕平，西原正志，江里口誠，野口智幸，西山雅則，南里悠介，田中淳，原英夫
- Organizer
  第27回日本脳ドック学会
- Data Source
  KAKENHI-PROJECT-17K09758
[Presentation] 教育講演：無症候性脳梗塞と脳小血管病2017
- Author(s)
  藥師寺祐介, 池田宗平，吉川正章, 原英夫
- Organizer
  第42回日本脳卒中学会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09758
[Presentation] Total small vessel disease scoreと腎機能の関連：The Kashima Scan Study2017
- Author(s)
  田中淳, 藥師寺祐介,江里口誠, 野口智幸, 原英夫
- Organizer
  第42回日本脳卒中学会
- Data Source
  KAKENHI-PROJECT-17K09758
[Presentation] 原発性脳アミロイドアンギオパチー関連脳出血の割合は東洋・西洋間で異なる2017
- Author(s)
  藥師寺祐介, 田中淳, 野口智幸, 河島雅到，井手俊宏, 永石友公子, 溝口恵，原英夫
- Organizer
  第42回日本脳卒中学会
- Data Source
  KAKENHI-PROJECT-17K09758
[Presentation] アルツハイマー型認知症の最新の治療とケア2017
- Author(s)
  原英夫
- Organizer
  第１１４回日本内科学会講演会　教育講演
- Invited
- Data Source
  KAKENHI-PROJECT-17K09758
[Presentation] Low-dose Phosphodiesterase III inhibitor reduces the vascular amyloid burden in Amyloid-β Protein Precursor Transgenic Mice.2017
- Author(s)
  Yakushiji Y, Kawamoto K, Uchihashi K, Nagaishi Y, Suzuyama K, Tsugitomi Y, Aoki S, Hara H.
- Organizer
  European Stroke Organization Conference 2017.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09758
[Presentation] 本邦におけるボストン基準による脳アミロイドアンギオパチー関連脳出血の診断制度の検討2017
- Author(s)
  七條千佳,藥師寺祐介,吉岡史隆,河島雅到,相島慎一,河本和裕,原英夫
- Organizer
  第42回日本脳卒中学会
- Data Source
  KAKENHI-PROJECT-17K09758
[Presentation] Validation study for the Japanese version of the Informant Questionnaire on Cognitive Decline on the Elderly (IQCODE-J).2017
- Author(s)
  Mizoguchi M, Yakushiji Y, Eriguchi M, Kosugi M, Sakamoto M, Horikawa E, Hara H.
- Organizer
  The 23rd World Congress of Neurology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09758
[Presentation] ステロイド療法で認知機能と活動性アミロイド関連画像異常が改善した一例2017
- Author(s)
  上床希久，薬師寺祐介，江里口誠，河本和裕，原英夫
- Organizer
  第220回日本神経学会九州地方会
- Data Source
  KAKENHI-PROJECT-17K09758
[Presentation] 無症候性脳出血性病変の頻度の検討：The Kashima Scan Study2017
- Author(s)
  吉川正章, 藥師寺祐介, 野口智幸, 小杉雅史, 原英夫
- Organizer
  第42回日本脳卒中学会
- Data Source
  KAKENHI-PROJECT-17K09758
[Presentation] アルツハイマー型認知症など神経変性疾患に対する免疫療法2017
- Author(s)
  原英夫
- Organizer
  第２９回日本神経免疫学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09758
[Presentation] Overview of disease modifying therapy trials for Alzheimer’s disease.2014
- Author(s)
  Hideo Hara
- Organizer
  第55回日本神経学会学術大会
- Place of Presentation
  福岡市福岡国際会議場
- Year and Date
  2014-05-21
- Data Source
  KAKENHI-PROJECT-24591266
[Presentation] 定型的な画像所見を呈し、新規GFAP遺伝子変異が示唆された成人発症Alexander病の1家系2013
- Author(s)
  岡孝之,小副川学、江里口誠、薬師寺祐介、吉田誠克、水田依久子、斉藤光象、原英夫
- Organizer
  第54回日本神経学会学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24591266
[Presentation] 非痙攣性てんかん重責で発症しQUIC法が診断に有用だった孤発性Creutzfeldt-Jakob disease(CJD)の一例2013
- Author(s)
  小川始至夏, 江里口誠, 岡孝之, 小杉雅史, 佐藤克也，雪竹基弘, 原英夫
- Organizer
  第18回日本神経感染症学会総会学術集会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-24591266
[Presentation] Immunopathological significance of ovarian teratoma in patients with anti-N-methyl-D-aspartate receptor encephalitis.2013
- Author(s)
  Tabata, Masanori Masuda,Makoto Eriguchi, Masatoshi Yokoyama, Yoshiyuki Takahashi, Keiko Tanaka, Motohiro Yukitake, Etuo Horikawa,Hideo Hara,
- Organizer
  XXIth World Congress of Neurology
- Place of Presentation
  Wien, Austria
- Data Source
  KAKENHI-PROJECT-24591266
[Presentation] An autopsy case of Perry syndrome with DCTN1 156T>A mutation.2013
- Author(s)
  Hideo Hara, Takayuki Oka, Masanori Masuda
- Organizer
  XXIth World Congress of Neurology
- Place of Presentation
  Wien, Austria
- Data Source
  KAKENHI-PROJECT-24591266
[Presentation] 根本的治療；今までの軌跡と未来への展望2013
- Author(s)
  原英夫
- Organizer
  第18回日本認知症科学会学術集会
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-24591266
[Presentation] 認知症の治療と将来への展望2013
- Author(s)
  原英夫
- Organizer
  認知症予防・治療・介護の最前線シンポジウム2013
- Place of Presentation
  出雲市医師会館
- Invited
- Data Source
  KAKENHI-PROJECT-24591266
[Presentation] 治療；抗認知症薬―現状と展望2013
- Author(s)
  原英夫
- Organizer
  第2回認知症研修会in米子
- Place of Presentation
  鳥取大学医学部記念講堂
- Invited
- Data Source
  KAKENHI-PROJECT-24591266
[Presentation] 認知機能障害で発症した神経サルコイドーシスの一例2012
- Author(s)
  鈴山耕平，薬師寺祐介，雪竹基弘，中橋弘顕，増田正憲，高橋幸利，田中恵子，原英夫
- Organizer
  第24回日本神経免疫学会学術集会
- Place of Presentation
  軽井沢
- Data Source
  KAKENHI-PROJECT-24591266
[Presentation] シンポジウム２　アルツハイマー病の根本的治療を目指してーワクチン療法の問題点―2012
- Author(s)
  原英夫
- Organizer
  第30回日本神経治療学会総会
- Place of Presentation
  北九州市
- Invited
- Data Source
  KAKENHI-PROJECT-24591266
[Presentation] 教育講演３アルツハイマー病の免疫療法2012
- Author(s)
  原英夫
- Organizer
  第31回日本認知症学会学術集会
- Place of Presentation
  つくば市
- Invited
- Data Source
  KAKENHI-PROJECT-24591266
[Presentation] Tumefactive mupltiple sclerosisの鑑別におけるASL画像の有用性2012
- Author(s)
  田中淳, 南里悠介, 薬師寺祐介, 雪竹基弘, 原英夫
- Organizer
  第53回日本神経学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24591266
[Presentation] アルツハイマー病のワクチン療法2007
- Author(s)
  原英夫、田平武
- Organizer
  第19回日本神経免疫学会学術集会
- Place of Presentation
  金沢
- Year and Date
  2007-04-13
- Data Source
  KAKENHI-PROJECT-17025056
[Presentation] Regulation of amyloid precursor protein expression by tetratricopeptide repeat protein 2
- Author(s)
  Hideo Hara, Takeshi Tabira
- Organizer
  Alzheimer’s Association International Conference 2014
- Place of Presentation
  Copenhagen, Denmark
- Year and Date
  2014-07-12 – 2014-07-17
- Data Source
  KAKENHI-PROJECT-24591266

1. KIRA Jun-ichi (40183305)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. WATANABE Takeshi (40028684)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. TABIRA Takeshi (80112332)

# of Collaborated Projects: 2 results

# of Collaborated Products: 19 results
4. TAKAHASHI Keikichi (40117148)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
5. 中山功一 (50420609)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
6. SEKIYAMA Atsuo (30403702)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. MATSUMOTO Shinei (40432950)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. NISHIMURA Taiji (10156119)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. KOYANAGI Yoshio (80215417)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. IWAKI Toru (40221098)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. TANAKA Shin (70134624)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. ARAKI Wataru (60311429)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
13. 松下祥 (50167649)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 今山修平 (70136430)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. TAKAO Keizo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. KAI Keita

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. TANAKA Keiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 三輪高喜

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 薬師寺祐介

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
20. 西岡健弥

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 齊藤聡

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hara Hideo 原 英夫

HARA Hideo 原 英夫

原 英夫 ハラ ヒデオ

Research Projects

Research Products

Co-Researchers

Bio-fabrication of cerebral amyloid angiopathy model using Bio-3D printer and analysis of the pathophysiological mechanisms.Principal Investigator

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Bio-fabrication of cerebral amyloid angiopathy model using Bio-3D printer and analysis of the pathophysiological mechanisms.Principal Investigator

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Analysis of chronic inflammation in the Alzheimer's brain and development of the treatment for the suppression of T cell activation.Principal Investigator

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Analysis of immune mechanisms of Alzheimer's disease and development of a novel treatment

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Identification of aging-related factors that facilitate Alzheimer's disease

Principal Investigator

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アストロサイト由来の自己反応性T細胞抑制因子の解明と遺伝子クローニングPrincipal Investigator

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ダニ抗原特異的なアトピーを特徴とする脊髄炎におけるTh2タイプT細胞応答の解析

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Establishment of a polyreactive T cell clone from Asian type multiple sclerosis patients and identification of the responsible antigens

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Regulation of T cell activity and detection of TCR-binding antigen by recombinant soluble TCR molecules

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Induction of chronic inflammatory myelopathy in rats infected with recombinant HTLV-I

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Analysis of the pathomechanism of the demyelinating diseases and the searach for the therapyPrincipal Investigator

Principal Investigator

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HTLV-I関連脊髄症におけるT細胞抗原受容体と抗原の解析Principal Investigator

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[Book] Innovations in nephrology.3D printers in nephrology2022

Author(s)

Hara Hideo 原英夫

HARA Hideo 原英夫

原英夫ハラヒデオ

[Book] 認知症ハンドブック第4章認知症の危険因子と予防. 1 認知症と危険因子の関係. A. 高血圧と認知症の関係2020