ITO Yoshinori 伊藤良則

Researcher Number	00261131
Other IDs
Affiliation (based on the past Project Information) *help	2012: 公益財団法人がん研究会, がん化学療法センター臨床部, 研究員 2011: 公益財団法人がん研究会, がん化学療法センター・臨床部, 研究員 2010: (財)癌研究会, 癌化学療法センター臨床部, 研究員 2005 – 2006: (財)癌研究会, 癌化学療法センター臨床部, 研究員 2004: 財団法人癌研究会, 癌化学療法センター・臨床部, 研究員 … More 2001: Japanese Found. for Cancer Res., Cancer Chemotherapy Center, Researcher, 癌化学療法センター臨床部, 研究員 1999 – 2001: 財団法人癌研究会, 癌化学療法センター・臨床部, 研究員 2000: (財)癌研究会, 癌化学療法センター臨床部, 研究員 2000: 財団法人癌研究会, 癌化学療法センター臨床部, 研究員 1998: 癌研究会, 癌化学療法センター臨床部, 研究員 1998: 癌研究會, 癌化学療法センター臨床部, 研究員 1997: 財団法人癌研究會, 癌化学療法センター臨床部, 研究員 1995 – 1997: 財団法人癌研究會, 癌化学療法センター・臨床部, 研究員 Less
Review Section/Research Field	Except Principal Investigator Gastroenterology / Endocrinology / Endocrinology / Clinical oncology / 内分泌・代謝学
Keywords	Except Principal Investigator breast cancer / 乳癌 / 骨転移 / hypercalcemia / bone metastases / cachexia / PTHrP / 5-fluorouracil / Biochemical modulator / p53 … More / RNA / TS / 骨吸収 / 破骨細胞 / hypercalcinoma / hypocalcaemia / predictive factor / DNA arrray / OPRT / gene expression / gastrointestinal cancer / 耐性遺伝子 / 予知指標 / DNA array / 耐性因子 / 遺伝子発現 / 消化器癌 / bone resorption / estrogen receptor / bone formation / osteoblast / bone metastasis / bone mophogenetic protein / bone morphogenetic proteins / 骨転位 / Estrogen receptor / 骨形成 / 骨芽細胞 / BMP / biochemical modulation / biochemical modulator / ビスホスホネート / 骨微小環境 / 骨髄微小転移 / Annexin II / 破骨細胞活性化因子 / 細胞接着 / AnnexinII Less

Elucidation of interaction between bone marrow micro-metastases in breast cancer patients
- Principal Investigator
  
  TAKAHASHI Syunji
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Clinical oncology
- Research Institution
  Japanese Foundation For Cancer Research
Roles of Parathyroid hormone-related protein (PTHrP) in bone metastases and cachexia of malignancy
- Principal Investigator
  
  TAKAHASHI Shunji
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  Japanese Foundation For Cancer Research
An investigation of gene expression profile
- Principal Investigator
  
  AIBA Keisuke
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  JIKEI UNIVERSITY SCHOOL OF MEDICINE
  Japanese Foundation For Cancer Research
Bone morphognetic proteins (BMPs) and BMP receptor expression in breast cancer cells and their significance in bone metastases
- Principal Investigator
  
  TAKAHASHI Shunji
- Project Period (FY)
  1998 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  Japanese Foundation for Cancer Research
An investigation of biochemical modulation and negatively autoregulated thymidylate synthase mechanism
- Principal Investigator
  
  AIBA Keisuke
- Project Period (FY)
  1997 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  JAPANESE FOUNDATION FOR CANCER RESEARCH
乳癌細胞におけるAnnexinIIの発現とその骨転移形成過程における意義
- Principal Investigator
  
  TAKAHASHI Syunji
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Japanese Foundation For Cancer Research

All 2013 2012 2011 2010 2006 2004 Other

All Journal Article Presentation

[Journal Article] Re: Superiority of denosumab to zoledronic acid for prevention of skeletal-related events: A combined analysis of three pivotal, randomised, phase 3 trials2013
- Author(s)
  Araki K, Ito Y, Takahashi S
- Journal Title
  
  Eur J Cancer
- Data Source
  KAKENHI-PROJECT-22501056
[Journal Article] Prognostic Factors for Overall Survival in Japanese Patients with Metastatic Renal Cell Cancer Treated with Sunitinib2012
- Author(s)
  Yuasa T, et al
- Journal Title
  
  BJU int.
  
  Volume: 130 Issue: 9 Pages: 677-84
- DOI
  10.1111/j.1464-410x.2011.10534.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592030, KAKENHI-PROJECT-22501056, KAKENHI-PROJECT-23659752
[Journal Article] Safety, Efficacy and Pharmacokinetics of Neratinib (HKI-272) in Japanese Patients with Advanced Solid Tumors: A Phase 1 Dose-escalation Study2012
- Author(s)
  Ito Y, Suenaga M, Hatake K, Takahashi S, Yokoyama M, Onozawa Y, Yamazaki K Hironaka S, Hashigami K, Hasegawa H, Takenaka N, Boku N
- Journal Title
  
  Jpn J Clin Oncol
  
  Volume: 42(4) Pages: 278-86
- Data Source
  KAKENHI-PROJECT-22501056
[Journal Article] Safety, Efficacy, and Pharmacokinetics of Neratinib (HKI-272) in Japanese Patients With Advanced Solid Tumors: A Phase 1 Dose-escalation Study.2012
- Author(s)
  Ito Y, Suenaga M, Hatake K, Takahashi S, YokoyamaM, Onozawa Y, Yamazaki K, Hironaka S, Hashigami K, Hasegawa H,　 Takenaka N, Boku N.
- Journal Title
  
  Jpn J Clin Oncol.
  
  Volume: 42 Issue: 4 Pages: 278-86
- DOI
  10.1093/jjco/hys012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501056
[Journal Article] Phase I study of dasatinib (BMS-354825) in Japanese patients with solid tumors2011
- Author(s)
  Takahashi S, Miyazaki M, Okamoto I, Ito Y, Ueda K, Seriu T, Nakagawa K, Hatake K
- Journal Title
  
  Cancer Sci
  
  Volume: 102(11) Pages: 2058-64
- NAID
  10030245266
- Data Source
  KAKENHI-PROJECT-22501056
[Journal Article] Treatment outcome and prognostic factors in renal cell cancer patients with bone metastasis2011
- Author(s)
  Yuasa T, Urakami S, Yamamoto S, Yonese J, Saito K, Takahashi S, Hatake K, Fukui I
- Journal Title
  
  Clin Exp Metastasis
  
  Volume: 28(4) Pages: 405-11
- Data Source
  KAKENHI-PROJECT-22501056
[Journal Article] Treatment outcome and prognostic factors in renal cell cancer patients with bone metastasis.2011
- Author(s)
  Yuasa T, Urakami S, Yamamoto S, Yonese J, Saito K, Takahashi S, Hatake K, Fukui I.
- Journal Title
  
  Clin Exp Metastasis.
  
  Volume: (Epub)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501056
[Journal Article] Detection of circulating tumor cells in peripheral blood of heavily treated metastatic breast cancer patients2011
- Author(s)
  Tokudome N, Ito Y, Takahashi S, Kobayashi K, Taira S, Tsutsumi C, Oto M, Oba M, Inoue K, Kuwayama A, Masumura K, Nakayama Y, Watanabe C, Hatake K
- Journal Title
  
  Breast Cancer
  
  Volume: 18 Issue: 3 Pages: 195-202
- DOI
  10.1007/s12282-011-0259-4
- NAID
  10029590079
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501056
[Journal Article] Phase I study of dasatinib (BMS-354825) in Japanese patients with solid tumors2011
- Author(s)
  Takahashi S, Miyazaki M, Okamoto I, Ito Y, Ueda K, Seriu T, Nakagawa K, Hatake K
- Journal Title
  
  Cancer Sci.
  
  Volume: 102 Issue: 11 Pages: 2058-64
- DOI
  10.1111/j.1349-7006.2011.02041.x
- NAID
  10030245266
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501056
[Journal Article] A lower dose of docetaxel at 60mg/m(2) could be continued longer for controlling peripheral edema in patients with metastatic breast cancer2011
- Author(s)
  Hosonaga M, Ito Y, Tokudome N, Takahashi S, Iwase T, Hatake K
- Journal Title
  
  Breast Cancer.
  
  Volume: (in press) Issue: 4 Pages: 329-334
- DOI
  10.1007/s12282-011-0297-y
- NAID
  10031146735
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501056
[Journal Article] Prospective randomized phase II study determines the clinical usefulness of genetic biomarkers for sensitivity to primary chemotherapy with paclitaxel in breast cancer2011
- Author(s)
  Yoshinori Ito, Koichi Nagasaki, Yoshio Miki, Takuji Iwase, Futoshi Akiyama, Masaaki Matsuura, Rie Horii, Masujiro Makita, Nahomi Tokudome, Masaru Ushijima, Masataka Yoshimoto, Shunji Takahashi, Tetsuo Noda and Kiyohiko Hatake
- Journal Title
  
  Cancer Sci
  
  Volume: 102(1) Pages: 130-6
- NAID
  10029288759
- Data Source
  KAKENHI-PROJECT-22501056
[Journal Article] Prospective randomized phase II study determines the clinical usefulness of genetic biomarkers for sensitivity to primary chemotherapy with paclitaxel in breast cancer.2010
- Author(s)
  Yoshinori Ito, Koichi Nagasaki, Yoshio Miki, Takuj Iwase, Futoshi Akiyama, Masaaki Matsuura, Rie Horii, Masujiro Makita, Nahomi Tokudome, Masaru Ushijima, Masataka Yoshimoto, Shunji Takahashi, Tetsuo Noda, Kiyohiko Hatake.
- Journal Title
  
  Cancer Sci.
  
  Volume: 120 Pages: 130-136
- NAID
  10029288759
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501056
[Journal Article] High-grade breast cancers include both highly sensitive and highly resistant subsets to cytotoxic chemotherapy.2010
- Author(s)
  Osako T, Horii R, Matsuura M, Domoto K, Ide Y, Miyagi Y, Takahashi S, Ito Y, Iwase T, Akiyama F
- Journal Title
  
  J Cancer Res Clin Oncol.
  
  Volume: 136 Pages: 1431-1438
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501056
[Journal Article] Common and discriminative clinicopathological features between breast cancers with pathological complete response or progressive disease in response to neoadjuvant chemotherapy.2010
- Author(s)
  Osako T, Horii R, Matsuura M, Ogiya A, Domoto K, Miyagi Y, Takahashi S, Ito Y, Iwase T, Akiyama F.
- Journal Title
  
  J Cancer Res Clin Oncol.
  
  Volume: 136 Pages: 233-241
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501056
[Journal Article] In vivo expansion of MDR1-transduced cells accompanied by a post-transplantation chemotherapy regimen with mitomycin C and methotrexate.2010
- Author(s)
  Mitsuhashi J, Hosoyama H, Tsukahara S, Katayama K, Noguchi K, Ito Y, Hatake K, Aiba K, Takahashi S, Sugimoto Y.
- Journal Title
  
  J Gene Med.
  
  Volume: 12 Pages: 596-603
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501056
[Journal Article] Common and discriminative clinicopathological features between breast cancers with pathological complete response or progressive disease in response to neoadjuvant chemotherapy2010
- Author(s)
  Osako T, Horii R, Matsuura M, Ogiya A, Domoto K, Miyagi Y, Takahashi S, Ito Y, Iwase T, Akiyama F
- Journal Title
  
  J Cancer Res Clin Oncol
  
  Volume: (2) Pages: 233-41
- Data Source
  KAKENHI-PROJECT-22501056
[Journal Article] High-grade breast cancers include both highly sensitive and highly resistant subsets to cytotoxic chemotherapy2010
- Author(s)
  Osako T, Horii R, Matsuura M, Domoto K, Ide Y, Miyagi Y, Takahashi S, Ito Y, Iwase T, Akiyama F
- Journal Title
  
  J Cancer Res Clin Oncol
  
  Volume: (9) Pages: 1431-8
- Data Source
  KAKENHI-PROJECT-22501056
[Journal Article] Gene therapy for breast cancer. -- Review of clinical gene therapy trials for breast cancer and MDR1 gene therapy trial in Cancer Institute Hospital.2006
- Author(s)
  S Takahashi, Y Ito, K Hatake, Y Sugimoto
- Journal Title
  
  Breast Cancer 13(1)
  
  Pages: 8-15
- NAID
  10017238537
- Data Source
  KAKENHI-PROJECT-16590917
[Journal Article] Blockade of bulky lymphoma-associated CD55 expression by RNA interference overcomes resistance to CDC with rituximab.2006
- Author(s)
  Terui Y, Sakurai T, Mishima Y, Mishima Y, Sugimura N, Sasaoka C, Kojima K, Yokoyama M, Mizunuma N, Takahashi S, Ito Y, Hatake K
- Journal Title
  
  Cancer Science 97
  
  Pages: 72-79
- Data Source
  KAKENHI-PROJECT-16590917
[Journal Article] Paclitaxel administered weekly in patients with docetaxel-resistant metastatic breast cancer : a single-center study2004
- Author(s)
  Sawaki M, Ito Y, Takahashi S, Hatake K et al.
- Journal Title
  
  Tumori 90(1)
  
  Pages: 36-39
- Data Source
  KAKENHI-PROJECT-16590917
[Journal Article] Efficacy and safety of trastuzumab as a single agent in heavily pretreated patients with HER-2/neu-overexpressing metastatic breast cancer2004
- Author(s)
  Sawaki M, Ito Y, Takahashi S, Hatake K. et al.
- Journal Title
  
  Tumori 90(1)
  
  Pages: 40-43
- Data Source
  KAKENHI-PROJECT-16590917
[Presentation] 早期乳癌患者に対するゾレドロン酸併用術前化学療法2012
- Author(s)
  中山美恵、高橋俊二、河合佑子、小林心、小林隆之、堤千寿子、田辺真彦、伊藤良則
- Organizer
  第2相試験中間報告第20回日本乳癌学会学術総会
- Place of Presentation
  熊本
- Year and Date
  2012-06-28
- Data Source
  KAKENHI-PROJECT-22501056
[Presentation] アロマターゼ阻害剤による骨代謝障害の予測因子2010
- Author(s)
  高橋俊二、徳留なほみ、伊藤良則、岩瀬拓士、畠清彦
- Organizer
  日本乳癌学会総会
- Place of Presentation
  札幌
- Year and Date
  2010-06-25
- Data Source
  KAKENHI-PROJECT-22501056
[Presentation] 早期乳癌患者に対するゾレドロン酸併用術前化学療法　第2相試験　中間報告
- Author(s)
  中山美恵、高橋俊二、河合佑子、小林心、小林隆之、堤千寿子、田辺真彦、伊藤良則
- Organizer
  第20回　日本乳癌学会学術総会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-22501056

1. TAKAHASHI Syunji (90221358)

# of Collaborated Projects: 5 results

# of Collaborated Products: 23 results
2. OGATA Etsuro (70013761)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. AIBA Keisuke (90150086)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. HORIKOSHI Noboru (00085648)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. MIZUNUMA Nobuyuki (40311229)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. KOBAYASHI Tadashi (50147310)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 鶴尾隆 (00012667)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 宇野真二 (70328293)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 湯浅健

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ITO Yoshinori 伊藤 良則

Research Projects

Research Products

Co-Researchers

Elucidation of interaction between bone marrow micro-metastases in breast cancer patients

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Roles of Parathyroid hormone-related protein (PTHrP) in bone metastases and cachexia of malignancy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

An investigation of gene expression profile

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Bone morphognetic proteins (BMPs) and BMP receptor expression in breast cancer cells and their significance in bone metastases

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

An investigation of biochemical modulation and negatively autoregulated thymidylate synthase mechanism

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

乳癌細胞におけるAnnexinIIの発現とその骨転移形成過程における意義

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Re: Superiority of denosumab to zoledronic acid for prevention of skeletal-related events: A combined analysis of three pivotal, randomised, phase 3 trials2013

Author(s)

Journal Title

Data Source

[Journal Article] Prognostic Factors for Overall Survival in Japanese Patients with Metastatic Renal Cell Cancer Treated with Sunitinib2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Safety, Efficacy and Pharmacokinetics of Neratinib (HKI-272) in Japanese Patients with Advanced Solid Tumors: A Phase 1 Dose-escalation Study2012

Author(s)

Journal Title

Data Source

[Journal Article] Safety, Efficacy, and Pharmacokinetics of Neratinib (HKI-272) in Japanese Patients With Advanced Solid Tumors: A Phase 1 Dose-escalation Study.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Phase I study of dasatinib (BMS-354825) in Japanese patients with solid tumors2011

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Treatment outcome and prognostic factors in renal cell cancer patients with bone metastasis2011

Author(s)

Journal Title

Data Source

[Journal Article] Treatment outcome and prognostic factors in renal cell cancer patients with bone metastasis.2011

Author(s)

Journal Title

Data Source

[Journal Article] Detection of circulating tumor cells in peripheral blood of heavily treated metastatic breast cancer patients2011

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Phase I study of dasatinib (BMS-354825) in Japanese patients with solid tumors2011

Author(s)

Journal Title

ITO Yoshinori 伊藤良則

[Presentation] 早期乳癌患者に対するゾレドロン酸併用術前化学療法　第2相試験　中間報告