AIHARA Noritaka 相原徳孝

… Alternative Names

相原徳孝アイハラノリタカ

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Researcher Number	00264739
Other IDs
Affiliation (Current)	2025: 名古屋市立大学, 医薬学総合研究院(医学), 教授
Affiliation (based on the past Project Information) *help	2025: 名古屋市立大学, 医薬学総合研究院(医学), 教授 2024: 名古屋市立大学, 医薬学総合研究院(医学), 准教授 2012: 名古屋市立大学, 医学(系)研究科(研究院), 講師 2010 – 2012: 名古屋市立大学, 大学院・医学研究科, 講師 2006: 名古屋市立大学, 大学院医学研究科, 講師 … More 2003 – 2006: 名古屋市立大学, 大学院・医学研究科, 講師 2002: Nagoya City University Graduate School of Medical Sciences, Research Associate, 大学院・医学研究科, 助手 1998 – 2001: Nagoya City University, Neurosurgery, Lecturer, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Cerebral neurosurgery / Basic Section 56010:Neurosurgery-related / Cerebral neurosurgery Except Principal Investigator Cerebral neurosurgery / Cerebral neurosurgery
Keywords	Principal Investigator 神経細胞 / 脳出血 / 腸内細菌叢 / アルツハイマー病 / アミロイド / CMRO2 / degenerarting neuron / MAPK / hjigher cortical dysfunction / myelencephalon-specific protease … More / Brain-deraived neurotrophic factor / traumatic brain injury / activated microglia / 神経変性 / 頭部外傷 / 外傷性ストレス / アンチセンス / マイクログリア / 神経栄養因子 / 高次機能 / 変性 / び慢性軸索損傷 / bcl-2 / bax / hypothermia / CA1 / immediate early gene / apoptosis / SAH / Delayad Nearoncl Death / vasospasm / rat / Subarachnoid hemorrhege / 脳血管萎縮 / アポトーシス / 頭蓋内圧 / 脳損傷 / 低体温 / 脳血管摩縮 / 脳虚血 / ラット / クモ膜下出血 / in situ hybidization / 海馬 / N-Cadherin / カイニン酸 / N-cadherin / てんかん / 神経可塑性 / 神経回路網 / neural stem cell / BBB / GFAP / 中枢神経移植 / 脳梗塞 / cerebral infarction / intracerebral hemorrhage / transplanation / neurosphere / stem cell … More Except Principal Investigator apoptosis / immediate early gene / MSP / p21 / アポトーシス / 凍結脳損傷 / BDNF / cerebral ischemia / Na / 脳損傷 / 線条体出血モデル / アクアポリン / neuron / subarachnoid hemorrhage / 低体温 / diffuse axonal / APP / stress gene / P21 / 脳虚血モデル / オリゴデンドロサイト / ラット / 頭蓋内圧 / choloid plexus / kaolin / rat / experimental model / communicating hydrocephalus / Aquaporin-4 / Aquaporin-1 / 正常圧水頭症 / 病態生理 / 水頭症 / 脈絡叢 / 実験モデル / カオリン / 交通性水頭症 / アクアポリン-4 / アクアポリン-1 / neuronal network / brain edema / regeneration after brain injury / cold injury / ischemic brain injury / oligodendrocyte / serine protease / myelencephalon specific protease / エミリン / 軸索損傷 / 神経再生 / 脳神経線維連絡 / 脳浮腫 / 損傷修復 / 虚血脳損傷 / セリンプロテアーゼ / head injury / cryogenic brain injury / brain injury / 頭部外傷 / 脳虚血 / methamphetamine-induced rotation / Myoinositol cotransporter / degeneration of substantia nigra / stem cell transplant / Striatal hemorrhage / Injury to the internal capsule / Neural disfunction / 神経栄養因子 / レトロウイルス / 片麻痺 / 脳出血 / メタアンフェタミン誘発回転運動 / ミオイノシトール・トランスポーター / 黒質変性 / 神経幹細胞移植 / 内包障害モデル / 神経機能障害 / hypothermia / anoptosis / spinal cord injury / 脊髄損傷 / osmolyte transporter / striatal hemorrhage / cultured astrocyte / myoinositol transporter / aquaporin / オスモライトトランスポータ / myoinsitoI cotranspoter / チャンネルトランスポータ / アストロサイト / 神経細胞 / オスモライト・トランスポータ / 神経幹細胞 / 培養グリア / くも膜下出血モデル / ミオイノシトール・トランスポータ / intracranial pressure / transporter / bcl-2 / ice / bax / TUNEL染色 / 脳幹流圧 / クモ膜下出血 / FK-506 / diffuse axonal injury / App / FK506 / CYCLIN DEPENDENT KINASE / P53 / GLIOMA CELL / APOPTOSIS / HEAT SHOCK / p-53 / glioma cell Line / heat-induced apoptosis / cyclin dependent kinase / p53 / glioma cell / heat shock / forced p21 expression / glia / mild cerebral ischemia / 細胞周期 / p21強制発現 / P21強制発現 / グリア細胞 / ストレス遺伝子 / 即時遺伝子 / 軽度脳虚血 / 局所脳虚血 / 頸動脈粥腫 / 3次元CT血管撮影(CTA) / 内膜剥離術(CEA) / ３次元CT血管撮影(CTA) / ステント装着術(CAS) / 内膜剥離術（CEA） / 頸動脈粥種 / マクロファージ / 血管平滑筋細胞 / HIF1α / VEGF / CTA / CAS / CEA / 頚動脈粥腫 / 頚動脈石灰化 / 頚動脈狭窄 / 蛋白表現 / 脳梁損傷モデル / 蛋白発現 / 遺伝子発現 / 凍結損傷モデル / シュワン細胞 / 脳内ストレス応答 / 実験的くも膜下出血 / 実験的水頭症 / 硬膜外圧 / 血管内圧 / 非侵襲的測定法 Less

膠芽腫に発現するATBF1のTGF-βシグナル伝達経路への関与についてPrincipal Investigator
- Principal Investigator
  
  相原徳孝
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Nagoya City University
ビフィズス菌MCC1274は脳アミロイドアンギオパチー関連脳出血を予防しうるかPrincipal Investigator
- Principal Investigator
  
  相原徳孝
- Project Period (FY)
  2024 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Nagoya City University
Establishment of surgical indication for carotid endareterectomy or carotid stening based on calcification and instability of plaques
- Principal Investigator
  
  YAMADA Kazuo
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Nagoya City University
Regeneration of injured axons with oligodendrocytic signal-processing systems as a marker
- Principal Investigator
  
  YAMADA Kazuo
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Nagoya City University
Upregulation of Auaporin-1 in experimental hydocephalus ameliorated with shunting
- Principal Investigator
  
  MASE Mitsuhito
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Nagoya City University
Analysis of role of new protease MSP in brain injury and/or repair by gene transfection
- Principal Investigator
  
  KATANO Hiroyuki
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  NAGOYA CITY UNIVERSITY
Cell transplantation therapy for hemiplegia after cerebral hemorrhage
- Principal Investigator
  
  YAMADA Kazuo
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Nagoya City University
Prevention of neurodegeneration after head injury by activated maicroglia with antisense methodPrincipal Investigator
- Principal Investigator
  
  AIHARA Noritaka
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Nagoya City University
組換え遺伝子導入シュワン細胞を用いた脳内白質の再生の試み
- Principal Investigator
  
  山田和雄
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Nagoya City University
Effect of local hypothermia in spinal cord injury
- Principal Investigator
  
  MOTOKI Tanikawa
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Nagoya City University
てんかん焦点形成におけるN-cadherinの役割とその制御による治療法の開発Principal Investigator
- Principal Investigator
  
  相原徳孝
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Nagoya City University
Analysis of channel transporter after brain injury and its application for treatment
- Principal Investigator
  
  YAMADA Kazuo
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Nagoya City University
アンチセンス法を用いたオリゴデンドロサイト機能抑制による中枢神経移植効果の改善Principal Investigator
- Principal Investigator
  
  相原徳孝
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Nagoya City University
APOPTOTIC CELL DEATH OF MALINGANT GLIOMA INDUCED BY HYPERTHERMIA : THE BASIC MECHANISMS AND CLINICAL APPLICATION
- Principal Investigator
  
  MASAGO Atsuo, 岩田明
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  NAGOYA CITY UNIVERSITY
Apoptosis after subarachnoid hemorrhage and its prevention
- Principal Investigator
  
  YAMADA Kazuyo
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Nagoya City University
EFFECTS OF IMMUNOSUPPRESSANT, FK-506 (TACROLIMUS), ON CHANGES OF BRAIN GENE EXPRESSION AFTER BRAIN INJURY : MOLICULAR BIOLOGICAL ANALYSIS OF INHIBITORY EFFECT OF APOPTOSIS
- Principal Investigator
  
  MASE Mitsuhito, 松本隆
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  NAGOYA CITY UNIVERSITY
非侵襲的頭蓋内圧測定法の開発
- Principal Investigator
  
  YAMADA Kazuo, 神谷健
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Nagoya City University
Prevention of apoptosis by p21 gene tranfer in central nervous system
- Principal Investigator
  
  YAMADA Kazuo
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Nagoya City University
Trearment for DIND and DND after subarachnoid hemorrhagePrincipal Investigator
- Principal Investigator
  
  AIHARA Noritaka, 神谷健
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Nagoya City University

All 2007 2004 2003 2002

All Journal Article Book

[Book] 脳出血に対する神経細胞移植研究(脳の科学第25巻増刊)2003
- Author(s)
  相原徳孝, 山田和雄, 西野仁雄, 他
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390440
[Book] 脳出血に対する神経細胞移植研究(脳の科学第25巻増刊)2003
- Author(s)
  相原徳孝, 山田和雄, 西野仁雄, 他
- Publisher
  脳の科学
- Data Source
  KAKENHI-PROJECT-15390440
[Journal Article] Oral adminisrtration of metal chelator ameliorates motor dysfunction after a small hemorrhage near the Internal capsule In rat2007
- Author(s)
  Masuda T, Hida H, Kanda Y, Aihara N, Ohta K, Yamada K, Nishino H
- Journal Title
  
  J Neurosci Res 85
  
  Pages: 213-222
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390406
[Journal Article] Tailor-made orbitocranioplasty for a sphenoorbital encephalocele presenting asa pulsatile exophthalmus2007
- Author(s)
  Katano H, Aihara H, Takeuchi Y, Nozaki M, Yamada K
- Journal Title
  
  J Neurosurg 106
  
  Pages: 126-130
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390406
[Journal Article] 脳出血モデル2004
- Author(s)
  相原徳孝, 山田和雄, 他
- Journal Title
  
  分子脳血管病 3
  
  Pages: 384-387
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390440
[Journal Article] Neurodegeneration of substantia nigra accompanied with macrophage/microglia infiltration after intrastriatal hemorrhage2003
- Author(s)
  Imamura N, Aihara N, Yamada K, et al.
- Journal Title
  
  Neurosci Res 46
  
  Pages: 289-298
- NAID
  10016206510
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390440
[Journal Article] The change of distribution and mRNA expression of brain-derived neurotrophic factor after intrastriatal hemorrhage2003
- Author(s)
  Kanda Y, Yamada K, Aihara N, et al.
- Journal Title
  
  International Congress Series 1252
  
  Pages: 291-296
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390440
[Journal Article] Neural transplantation for intracerebral hemorrhage model rats experience of CEA without conventional angiography2002
- Author(s)
  Kanda Y, Aihara N, Yamada K, et al.
- Journal Title
  
  Neurotrauma Res 14
  
  Pages: 8-11
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390440

1. YAMADA Kazuo (90150341)

# of Collaborated Projects: 16 results

# of Collaborated Products: 8 results
2. MASE Mitsuhito (60238920)

# of Collaborated Projects: 12 results

# of Collaborated Products: 0 results
3. IWATA Akira (90275131)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
4. KATANO Hiroyuki (30295612)

# of Collaborated Projects: 5 results

# of Collaborated Products: 1 results
5. MASAGO Atsuo (70209419)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
6. KATO Taiji (60094364)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
7. TANIKAWA Motoki (20343402)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
8. ASAI Kiyofumi (70212462)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
9. SHIMADA Shoichi (20216063)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. YAMASHITA Nobuko (80220341)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. UMEMURA Atsushi (00244567)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. KOMATSU Hiroaki (90305540)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. 神谷健 (70137115)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. 松本隆 (50199676)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. NAKANISHI Makoto (40217774)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. FUSE Takahisa (00229080)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. YAMAMOTO Kenichi (80372837)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 加藤康二郎 (30315890)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 竹内洋太郎 (40305545)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 金井秀樹 (90185893)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 丹羽裕史 (40343404)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 鄭且均 (00464579)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

AIHARA Noritaka 相原 徳孝

相原 徳孝 アイハラ ノリタカ

Research Projects

Research Products

Co-Researchers

膠芽腫に発現するATBF1のTGF-βシグナル伝達経路への関与についてPrincipal Investigator

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ビフィズス菌MCC1274は脳アミロイドアンギオパチー関連脳出血を予防しうるかPrincipal Investigator

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Prevention of neurodegeneration after head injury by activated maicroglia with antisense methodPrincipal Investigator

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てんかん焦点形成におけるN-cadherinの役割とその制御による治療法の開発Principal Investigator

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アンチセンス法を用いたオリゴデンドロサイト機能抑制による中枢神経移植効果の改善Principal Investigator

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AIHARA Noritaka 相原徳孝

相原徳孝アイハラノリタカ