NISHIMOTO Masazumi 西本正純

… Alternative Names

西本正純ニシモトマサズミ

Less

Researcher Number	00265406
Other IDs
Affiliation (Current)	2025: 埼玉医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2010 – 2012: 埼玉医科大学, 医学部, 講師 2006 – 2007: 埼玉医科大学, 医学部, 講師 2001: Saitama Medical School, Faculty of Medicine, Lecturer, 医学部, 講師 2000: 埼玉医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator General medical chemistry / General medical chemistry / Tumor biology
Keywords	Principal Investigator 胚性幹細胞 / Oct-4 / 多能性 / 胚性肝細胞 / Phosphorylation / pluripotency / embryonic stem cell / リン酸化 / POU-domain / undifferentiated state … More / pluripotent / octamer factor / OCT-3 / ES cells / 全能性 / POU-ドメイン / 未分化状態 / オクタマーファクター / Oct-3 / 足場非依存的増殖 / がん幹細胞 / 形質転換 / utf1 / ジーンターゲティング / UTF1 / 幹細胞 Less

Analyzing the common mechanism underlying the maintenance of tumorigenity in cancer stem and embryonic stem cellsPrincipal Investigator
- Principal Investigator
  
  NISHIMOTO Masazumi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Saitama Medical University
Possibik of the Oct-4 phosphorylationPrincipal Investigator
- Principal Investigator
  
  NISHIMOTO Masazumi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Saitama Medical University
Isolation of Oct6 mutant which can sustain the ES cell pluripotencyPrincipal Investigator
- Principal Investigator
  
  NISHIMOTO Masazumi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  SAITAMA MEDICAL SCHOOL

All 2012 2011 2010 2006 Other

All Journal Article Presentation Book

[Book] 新遺伝子工学ハンドブック2010
- Author(s)
  西本正純
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-22501017
[Journal Article] Sirt1, p53, and p38(MAPK) are crucial regulators of detrimental phenotypes of embryonic stem cells with Max expression ablation2012
- Author(s)
  Hishida T. Nozaki Y. Nakachi Y. Mizuno Y. Iseki H. Katano M. Kamon M. Hirasaki M. Nishimoto M. Okazaki Y. Okuda A.
- Journal Title
  
  Stem Cells
  
  Volume: 30 Pages: 1634-44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501017
[Journal Article] Indefinite self-renewal of ESCs through Myc/Max transcriptional complex-independent mechanisms.2011
- Author(s)
  Hishida T. Nozaki Y. Nakachi Y. Mizuno Y. Okazaki Y. Ema M. Takahashi S. Nishimoto M. Okuda A.
- Journal Title
  
  Cell Stem Cell
  
  Volume: 9 Pages: 37-49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501017
[Journal Article] Regulatory region 2 functions as a neural stem cell-specific enhancer In the telencephalon2006
- Author(s)
  Miyagi, S., Nishimoto, M., Saitoh, T., Ninomiya, M., Sawamoto, K., Okano, H., Muramatsu, M., Oguro, H., lwama, A., Okuda, A
- Journal Title
  
  J. boil. Chem 281
  
  Pages: 13374-13381
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590275
[Journal Article] Putative sternness gene JamB is not required for maintenance of stemm cell State of embryonic, neural, and hematopoietic stem cell2006
- Author(s)
  Sakaguchi, T., Nishimoto, M., Miyagi, S., lwama, A., Morita, Y., lwamori, N., Nakauchi, H., Kiyonari, H., Muramatsu, M., okuda, A
- Journal Title
  
  Mol. Cell. Biol 26
  
  Pages: 6557-6570
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590275
[Journal Article] UTF1に着目した胚性幹細胞(ES細胞)の癌化抑制への取組み2006
- Author(s)
  西本正純
- Journal Title
  
  医学の歩み 217
  
  Pages: 215-216
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590275
[Presentation] 真獣類特異的遺伝子 UTF1は胎盤の増殖を促進する2012
- Author(s)
  西本正純
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡市
- Year and Date
  2012-12-13
- Data Source
  KAKENHI-PROJECT-22501017
[Presentation] partial iPS 細胞から真の iPS 細胞への変換に関与する因子としての Cnot2 の同定2012
- Author(s)
  加門正義、西本正純、他5名
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡市
- Year and Date
  2012-12-13
- Data Source
  KAKENHI-PROJECT-22501017
[Presentation] Context-dependent requirement of Myc/Max complexes for the maintenance of the indefinite self-renewal of ES cells.2011
- Author(s)
  菱田友昭、西本正純、他7名
- Organizer
  第34回日本分子生物学会
- Place of Presentation
  横浜市
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PROJECT-22501017
[Presentation] Eutheria-specific UTF1 gene is critical for the placental growth.2011
- Author(s)
  西本正純、他11名
- Organizer
  第34回日本分子生物学会
- Place of Presentation
  横浜市
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PROJECT-22501017
[Presentation] Eutheria-specific UTF1 gene is critical for the placental growth2011
- Author(s)
  Masazumi Nishimoto
- Organizer
  日本分子生物学会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PROJECT-22501017
[Presentation] Epigenetic regulation of clock gene during the differentiation of embryonic stem cells.2011
- Author(s)
  大西芳秋、奥田晶彦、西本正純
- Organizer
  第34回日本分子生物学会
- Place of Presentation
  横浜市
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PROJECT-22501017
[Presentation] Partial iPS 細胞を真の iPS 細胞へと変換させる能力を持つ遺伝子のゲノムワイドスクリーニングによる同定、2011
- Author(s)
  加門正義、西本正純、他5名
- Organizer
  第34回日本分子生物学会
- Place of Presentation
  横浜市
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PROJECT-22501017
[Presentation] cMyc/Max 複合体は ES 細胞の LIF を介した自己複製および分化多能性維持に必須である2010
- Author(s)
  菱田友昭、西本正純、他3名
- Organizer
  第33回日本分子生物学会
- Place of Presentation
  神戸市
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-22501017
[Presentation] 胚性幹細胞における時計遺伝子の転写とクロマチン状態の関連について2010
- Author(s)
  西本正純
- Organizer
  第33回日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-22501017
[Presentation] Establishment of partial iPS cells representing a novel intermediate state which are more advanced than those previously reported.2010
- Author(s)
  加門正義、西本正純、他5名
- Organizer
  第33回日本分子生物学会
- Place of Presentation
  神戸市
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-22501017
[Presentation] 胚性幹細胞における時計遺伝子の転写とクロマチンの状態との関連について2010
- Author(s)
  西本正純、他2名
- Organizer
  第33回日本分子生物学会
- Place of Presentation
  神戸市
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-22501017
[Presentation] 胎盤を持つ哺乳類に特異的な遺伝子な一つである UTF1 遺伝子の胎盤形成における寄与2010
- Author(s)
  西本正純、他8名
- Organizer
  第33回日本分子生物学会
- Place of Presentation
  神戸市
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-22501017
[Presentation] 真獣類特異的遺伝子UTF1は胎盤の増殖を促進する
- Author(s)
  西本正純
- Organizer
  日本分子生物学会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-22501017

1. NOGI Yasuhisa (60101937)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

NISHIMOTO Masazumi 西本 正純

西本 正純 ニシモト マサズミ

Research Projects

Research Products

Co-Researchers

Analyzing the common mechanism underlying the maintenance of tumorigenity in cancer stem and embryonic stem cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Possibik of the Oct-4 phosphorylationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Isolation of Oct6 mutant which can sustain the ES cell pluripotencyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 新遺伝子工学ハンドブック2010

Author(s)

Publisher

Data Source

[Journal Article] Sirt1, p53, and p38(MAPK) are crucial regulators of detrimental phenotypes of embryonic stem cells with Max expression ablation2012

Author(s)

Journal Title

Data Source

[Journal Article] Indefinite self-renewal of ESCs through Myc/Max transcriptional complex-independent mechanisms.2011

Author(s)

Journal Title

Data Source

[Journal Article] Regulatory region 2 functions as a neural stem cell-specific enhancer In the telencephalon2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Putative sternness gene JamB is not required for maintenance of stemm cell State of embryonic, neural, and hematopoietic stem cell2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] UTF1に着目した胚性幹細胞(ES細胞)の癌化抑制への取組み2006

Author(s)

Journal Title

Description

Data Source

[Presentation] 真獣類特異的遺伝子 UTF1は胎盤の増殖を促進する2012

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] partial iPS 細胞から真の iPS 細胞への変換に関与する因子としての Cnot2 の同定2012

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Context-dependent requirement of Myc/Max complexes for the maintenance of the indefinite self-renewal of ES cells.2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Eutheria-specific UTF1 gene is critical for the placental growth.2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Eutheria-specific UTF1 gene is critical for the placental growth2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

NISHIMOTO Masazumi 西本正純

西本正純ニシモトマサズミ