ISHII Genichiro 石井源一郎

Researcher Number	00270869
Affiliation (Current)	2024: 国立研究開発法人国立がん研究センター, 東病院, 科長
Affiliation (based on the past Project Information) *help	2021 – 2024: 国立研究開発法人国立がん研究センター, 東病院, 科長 2016 – 2020: 国立研究開発法人国立がん研究センター, 先端医療開発センター, 分野長 2017: 独立行政法人・国立がん研究センター, 臨床腫瘍病理部, 室長 2016: 国立研究開発法人国立がん研究センター, 先端医療開発センター, ユニット長 2015: 国立研究開発法人国立がん研究センター, 東病院, ユニット長 … More 2014: 独立行政法人国立がん研究センター, 東病院, ユニット長 2014: 国立がん研究センター, 東病院・臨床開発センター, ユニット長 2012 – 2014: 独立行政法人国立がん研究センター, 臨床開発センター, ユニット長 2012: 独立行政法人国立がん研究センター, 臨床開発センター, 室長 2010: National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East, 臨床開発センター, 室長 2009: National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East, 臨床腫瘍病理部, 室長 2008: National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East, 臨床腫瘍病理部, 室長 2006: National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East, National Cancer Center Innovative Medical Research Center, 室長 2006: 国立がんセンター(研究所及び東病院臨床開発センター), 臨床腫瘍病理部, 室長 2005: 国立がんセンター(研究所及び東病院臨床開発センター), 東病院臨床開発センター・臨床腫瘍病理部, 室長 2004: National Cancer Center Research Institute East, 臨床腫瘍病理部, 室長 2003: 国立がんセンター, 研究所・臨床腫瘍病理部, 室長 2002: 国立がんセンター, 臨床腫瘍病理部, 室長 2001: 千葉大学, 大学院・医学研究院, 講師 2000: 千葉大学, 医学部, 講師 1995 – 1998: 千葉大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Experimental pathology / Experimental pathology / Basic Section 53030:Respiratory medicine-related / Medium-sized Section 50:Oncology and related fields / Respiratory organ internal medicine / Human pathology / Hematology Except Principal Investigator Basic Section 90120:Biomaterials-related / Basic Section 49020:Human pathology-related / Basic Section 90130:Medical systems-related … More / Digestive surgery / Science and Engineering / Clinical oncology / Biological Sciences Less
Keywords	Principal Investigator がん微小環境 / GFP / がん関連線維芽細胞 / 微小環境 / 線維芽細胞 / がん間質 / Stromal reaction / Cancer microenvironment / Bone marrow derived fibroblast / Epstein-Barr virus … More / がん進展 / 繊維芽細胞 / 薬物療法 / 薬剤耐性がん微小環境 / 薬剤耐性 / 線維芽細胞依存性浸潤 / Podoplanin / 浸潤 / がん幹細胞 / 癌 / トランスレーショナルリサーチ / 病理学 / EGFR変異 / 感受性 / 肺がん / 分子標的薬 / 薬剤感受性 / EGFR-TKI / 肺腺癌 / carbonic anhydrase IX / cytokeratin 8 / 骨髄由来 / 動員 / Carbonic anhydrase IX / Cytokeratin 8 / 動員機構 / Cancer progression / Animal model / Bone marrow derived cell / Cancer cell / desmoplastic reaction / SCIDマウス / 筋線維芽細胞 / モデルマウス / 間質反応 / 骨髄細胞 / がん細胞 / 筋線維芽細胞細胞 / Gastric carcinoma / Hodgkin's disease / Latent membrane protein-1 / bcl-2免疫染色 / EBV関連胃癌 / EBV種地域差 / 欠失LMP-1遺伝子 / 胃癌 / ホジキン病 / LMP-1 / EBウイルス / gastric carsinoma / Hodgkin′s disease / Latent memhranl protein-1 / がん間質細胞の分子標的治療法 / がんの進展、転移 / がん組織 / 分子標的 / がん生着 / 間葉系幹細胞 / 間葉系前駆細胞 / differentiation / MAPK / Notch / 造血細胞 / transgenic mouse / IL-11 / 凍結切片結合試験 / VC M-1 / VLA-4 / 濾胞樹状細胞 / 濾胞性リンパ腫 … More Except Principal Investigator 融合タンパク / アルツハイマー病 / 急性期脳梗塞 / 薬物ターゲティング / 血栓溶解 / AI病理学 / デジタル病理学 / 病理組織 / 治療効果予測 / 形態学的バイオマーカー / 多元データベース構築 / 早期肺がんの定量的診断 / 再発・予後予測 / 非造影・造影高精度CT画像 / 3次元テクスチャ構造解析 / リンパ節転移予測 / 予後予測 / 非造影・造影高精細CT画像 / 肺がん / 癌—間質相互作用 / ラッグデリバリー / トキシン / 癌-間質相互作用 / 癌 / CAF（癌関連線維芽細胞） / 膵臓外科学 / がんー間質相互作用 / がん関連線維芽細胞:CAF / ドラッグデリバリー / レクチン / 糖鎖 / CAF (がん関連線維芽細胞） / 癌ー間質相互作用 / 膵癌 / マルチスケール・マルチモダリティ画像 / 肺・大腸・肝臓に発生する悪性腫瘍の本態解明 / 3次元ミクロからマクロの病態 / 肺を中心に大腸・腎臓に発生する悪性腫瘍の本態解明 / マルチスケール・マルチモダリティ画像データベース / 腫瘍診断支援システム / 多元計算解剖モデル / カタログ情報 / 小細胞肺癌 / PI3K/AKT/mTOR経路 / 予後不良 / 網羅的 / 臨床情報 / 候補遺伝子 / SNPアレイ / 全エクソン解析 / 小細胞肺がん / チロシンリン酸化 / FAK / Rho / マトリックスメタロプロテイアーゼ / 浸潤 / 腫瘍 / 細胞運動 / CD44 Less

New frontiers of thrombolytic agents: Applications of a novel thrombolytic agent to acute and chronic cranial nerve diseases.
- Principal Investigator
  
  横山昌幸
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  Jikei University School of Medicine
Study of cancer-associated fibroblasts in tumor re-progression after chemotherapyPrincipal Investigator
- Principal Investigator
  
  石井源一郎
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  National Cancer Center Japan
Development study on pathological predictive biomarkers for cancer treatment
- Principal Investigator
  
  元井紀子
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Research Institute for Clinical Oncology Saitama Cancer Center
Quantitative diagnosis of early-stage lung cancer by fusing non-contrast and contrast high-definition CT images
- Principal Investigator
  
  KAWATA Yoshiki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90130:Medical systems-related
- Research Institution
  The University of Tokushima
Fibroblast-dependent cancer cell invasionPrincipal Investigator
- Principal Investigator
  
  Genichiro Ishii
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  National Cancer Center Japan
CD200-positive cancer associated fibroblasts augment the sensitivity of Epidermal Growth Factor Receptor mutation-positive lung adenocarcinomas to EGFR Tyrosine kinase inhibitorsPrincipal Investigator
- Principal Investigator
  
  Genichiro Ishii
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  National Cancer Center Japan
iCAF: Cancer associated fibroblast derived from iPS cells and its surface glycan as a target of cancer therapy.
- Principal Investigator
  
  Tatsuya ODA
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  University of Tsukuba
Cancer Diagnosis and Prognosis Assistance Based on Multidisciplinary Computational Anatomy
- Principal Investigator
  
  Niki Noboru
- Project Period (FY)
  2014 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  The University of Tokushima
Comprehensive genomic analysis of small cell lung cancer exploring mechanisms of the proliferation and therapeutic targets
- Principal Investigator
  
  GOTO Koichi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Clinical oncology
- Research Institution
  National Cancer Center Japan
Development of target therapy for stromal cellsPrincipal Investigator
- Principal Investigator
  
  ISHII Genichiro
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Experimental pathology
- Research Institution
  National Center of Neurology and Psychiatry
Mechanism of tumor promoting effect by mesenchymal progenitor cellPrincipal Investigator
- Principal Investigator
  
  ISHII Genichiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
In vivo and in vitro characterization of bone-marrow derived fibroblast recruited into cancer induced stroma.Principal Investigator
- Principal Investigator
  
  ISHII Genichiro
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
Characterization of bone-marrow derived fibroblast recruited into cancer induced stroma.Principal Investigator
- Principal Investigator
  
  ISHII Genichiro
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  National Cancer Center Research Institute East
Notchシグナルにより制御される、造血細胞分化の分子メカニズムについての解析Principal Investigator
- Principal Investigator
  
  石井源一郎
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  Chiba University
CD44の細胞運動・転移関連遺伝子発現における役割
- Principal Investigator
  
  HARIGAYA Kenichi
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Chiba University
Epstein-Barr virus latent membrane protein-1 oncogene deletions in Hodgkin's disease and gastric carcinoma in Japan and Nepal.Principal Investigator
- Principal Investigator
  
  ISHII Genichiro, 三方淳男
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  SCHOOL OF MEDICINE, CHIBA UNIVERSITY
トランスジェニックマウスを用いたIL-11の生理機能の解析Principal Investigator
- Principal Investigator
  
  石井源一郎
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Experimental pathology
- Research Institution
  Chiba University
濾胞性リンパ腫における腫瘍細胞と濾胞樹状細胞間相互作用の機能解析Principal Investigator
- Principal Investigator
  
  石井源一郎
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Experimental pathology
- Research Institution
  Chiba University

[Journal Article] Prognostic value of predominant subtype in pathological stage II?III lung adenocarcinoma with epidermal growth factor receptor mutation2024
- Author(s)
  Kitagawa Shingo、Zenke Yoshitaka、Taki Tetsuro、Aokage Keiju、Sakai Tetsuya、Shibata Yuji、Izumi Hiroki、Nosaki Kaname、Umemura Shigeki、Matsumoto Shingo、Yoh Kiyotaka、Sakamoto Naoya、Sakashita Shingo、Kojima Motohiro、Tsuboi Masahiro、Goto Koichi、Ishii Genichiro
- Journal Title
  
  Lung Cancer
  
  Volume: 188 Pages: 107453-107453
- DOI
  10.1016/j.lungcan.2023.107453
- Data Source
  KAKENHI-PROJECT-21H02931
[Journal Article] Representation of thoracic N1 lymph nodes group in contrast-enhanced CT images using distance maps based on tracheobronchial labeling2023
- Author(s)
  Yoshiki Kawata, Hidenobu Suzuki, Yuji Matsumoto, Takaaki Tsuchida, Keiju Aokage, Genichiro Ishii, Masahiro Kusumoto, Noboru Nik
- Journal Title
  
  Proc. SPIE. 12468, Medical Imaging 2023: Biomedical Applications in Molecular, Structural, and Functional Imaging
  
  Volume: 12468 Pages: 28-28
- DOI
  10.1117/12.2654257
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H04551
[Journal Article] 18F-fluorodeoxyglucose uptake in PET is associated with the tumor microenvironment in metastatic lymph nodes and prognosis in N2 lung adenocarcinoma2022
- Author(s)
  Nomura K, Nakai T, Nishina Y, Sakamoto N, Miyoshi T, Tane K, Samejima J, Aokage K, Kojima M, Sakashita S, Taki T, Miyazaki S, Watanabe R, Suzuki K, Tsuboi M, Ishii G.
- Journal Title
  
  Cancer Science
  
  Volume: 113(4) Issue: 4 Pages: 1488-1496
- DOI
  10.1111/cas.15266
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K20821, KAKENHI-PROJECT-21H02931
[Journal Article] Cancer-associated fibroblast-dependent and -independent invasion of gastric cancer cells.2022
- Author(s)
  Kondo R, Sakamoto N, Harada K, Hashimoto H, Morisue R, Yanagihara K, Kinoshita T, Kojima M, Ishii G.
- Journal Title
  
  J Cancer Res Clin Oncol.
  
  Volume: on line ahead of print Issue: 8 Pages: 5309-5319
- DOI
  10.1007/s00432-022-04484-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07013, KAKENHI-PROJECT-21H02931
[Journal Article] The area of residual tumor predicts esophageal squamous cell carcinoma prognosis following neoadjuvant chemotherapy2022
- Author(s)
  Adachi Masahiro、Aoyama Naoki、Kojima Motohiro、Sakamoto Naoya、Miyazaki Saori、Taki Tetsuro、Watanabe Reiko、Matsuura Kazuto、Kotani Daisuke、Kojima Takashi、Fujita Takeo、Tabuchi Keiji、Ishii Genichiro、Sakashita Shingo
- Journal Title
  
  Journal of Cancer Research and Clinical Oncology
  
  Volume: Online ahead of print Issue: 8 Pages: 4663-4673
- DOI
  10.1007/s00432-022-04366-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06899, KAKENHI-PROJECT-21H02931, KAKENHI-PROJECT-20K22859
[Journal Article] Pathologic method for extracting good prognosis group in triple negative breast cancer after neoadjuvant chemotherapy.2022
- Author(s)
  Eguchi Y, Nakai T, Kojima M, Wakabayashi M, Sakamoto N, Sakashita S, Miyazaki S, Taki T, Watanabe R, Watanuki R, Yamauchi C, Iwatani T, Mukohara T, Onishi T, Ishii G.
- Journal Title
  
  Cancer Science
  
  Volume: 113(4) Issue: 4 Pages: 1507-1518
- DOI
  10.1111/cas.15273
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K20821, KAKENHI-PROJECT-21K06899, KAKENHI-PROJECT-21K10364, KAKENHI-PROJECT-21H02931, KAKENHI-PROJECT-20K22859
[Journal Article] Cancer-associated fibroblasts and the tumor microenvironment in non-small cell lung cancer2022
- Author(s)
  Suzuki Jun、Tsuboi Masahiro、Ishii Genichiro
- Journal Title
  
  Expert Review of Anticancer Therapy
  
  Volume: 22 Issue: 2 Pages: 169-182
- DOI
  10.1080/14737140.2022.2019018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H02931
[Journal Article] Gemella haemolysans inhibits the growth of the periodontal pathogen Porphyromonas gingivalis.2021
- Author(s)
  Miyoshi T, Oge S, Nakata S, Ueno Y, Ukita H, Kousaka R, Miura Y, Yoshinari N, Yoshida A.
- Journal Title
  
  Scientific reports
  
  Volume: 11(1) Issue: 8 Pages: 11742-11742
- DOI
  10.1111/pin.13110
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06494, KAKENHI-PROJECT-21H02931
[Journal Article] Representation of texture structures with topological data analysis for stage IA lung adenocarcinoma in three-dimensional thoracic CT images2021
- Author(s)
  Kawata Yoshiki、Niki Noboru、Kusumoto Masahiko、Ohamatsu Hironobu、Aokage Keiju、Ishii Genichiro、Matsumoto Yuji、Tsuchida Takaaki、Eguchi Kenji、Kaneko Masahiro
- Journal Title
  
  Proceedings of SPIE
  
  Volume: 11600 Pages: 13-13
- DOI
  10.1117/12.2581710
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H04551
[Journal Article] Comprehensive assessment of PD-L1 expression, tumor mutational burden and oncogenic driver alterations in non-small cell lung cancer patients treated with immune checkpoint inhibitors2021
- Author(s)
  Yoh Kiyotaka、Matsumoto Shingo、Furuya Naoki、Nishino Kazumi、Miyamoto Shingo、Oizumi Satoshi、Okamoto Norio、Itani Hidetoshi、Kuyama Shoichi、Nakamura Atsushi、Nishi Koichi、Fukuda Ikue、Tsuta Koji、Hayashi Yuichiro、Motoi Noriko、Ishii Genichiro、Goto Koichi
- Journal Title
  
  Lung Cancer
  
  Volume: 159 Pages: 128-134
- DOI
  10.1016/j.lungcan.2021.07.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07036, KAKENHI-PROJECT-21K06900
[Journal Article] Fibroblasts-dependent Invasion of Podoplanin-Positive Cancer Stem Cells in Squamous Cell Carcinoma2020
- Author(s)
  Miyashita T, Neri S, Hashimoto H, Akutsu A, Sugano M, Fujii S, Ochiai A, Ishii G.
- Journal Title
  
  J Cell Physiol.
  
  Volume: ＸＸ Issue: 10 Pages: 7251-7260
- DOI
  10.1002/jcp.29624
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19488
[Journal Article] Spatiotemporal characteristics of fibroblasts-dependent cancer cell2019
- Author(s)
  Tomoyuki Miyashita, Ishii Genichiro. et al
- Journal Title
  
  Journal of Cancer Research and Clinical Oncology
  
  Volume: 145 Issue: 2 Pages: 373-381
- DOI
  10.1007/s00432-018-2798-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19488
[Journal Article] Computer-aided CT image features improving the malignant risk prediction in pulmonary nodules suspicious for lung cancer2019
- Author(s)
  Y. Kawata, T. Kageyama, N. Niki, M. Kusumoto, H. Ohmatsu, K. Aokage, G. Ishii, Y. Matsumoto, T. Tsuchida, K. Eguchi, M. Kaneko
- Journal Title
  
  Proc. SPIE 10950, SPIE Medical Imaging 2019
  
  Volume: - Pages: 55-55
- DOI
  10.1117/12.2512614
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-26108001, KAKENHI-PLANNED-26108007
[Journal Article] The ratio of cancer cells to stroma within the invasive area is a histologic prognostic parameter of lung adenocarcinoma.2018
- Author(s)
  Ichikawa T, Aokage K, Sugano M, Miyoshi T, Kojima M, Fujii S, Kuwata T, Ochiai A, Suzuki K, Tsuboi M, Ishii G.
- Journal Title
  
  Lung Cancer
  
  Volume: 118 Pages: 30-35
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-26108007
[Journal Article] Differences of tumor microenvironment between stage I lepidic-positive and lepidic-negative lung adenocarcinomas.2018
- Author(s)
  Katsumata S, Aokage K, Miyoshi T, Tane K, Nakamura H, Sugano M, Kojima M, Fujii S, Kuwata T, Ochiai A, Hayashi R, Tsuboi M, Ishii G.
- Journal Title
  
  J Thorac Cardiovasc Surg
  
  Volume: 156(4) Issue: 4 Pages: 1679-1688
- DOI
  10.1016/j.jtcvs.2018.05.053
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-26108001, KAKENHI-PLANNED-26108007
[Journal Article] Influence of ground-glass opacity and the corresponding pathological findings on survival in patients with clinical stage I non-small cell lung cancer2018
- Author(s)
  K.Aokage, T.Miyoshi, Gshii, M.Kusumoto, S.Nomura, S.Katsumata, K.Sekihara, K.Tane, M.Tsuboi
- Journal Title
  
  J Thorac Oncol.
  
  Volume: 13 Issue: 4 Pages: 533-542
- DOI
  10.1016/j.jtho.2017.11.129
- Peer Reviewed
- Data Source
  KAKENHI-INTERNATIONAL-15K21716, KAKENHI-PLANNED-26108007, KAKENHI-ORGANIZER-26108001
[Journal Article] CD200-positive cancer associated fibroblasts augment the sensitivity of Epidermal Growth Factor Receptor mutation-positive lung adenocarcinomas to EGFR Tyrosine kinase inhibitors.2017
- Author(s)
  Ishibashi M, Neri S, Hashimoto H, Miyashita T, Yoshida T, Nakamura Y, Udagawa H, Kirita K, Matsumoto S, Umemura S, Yoh K, Niho S, Tsuboi M, Masutomi K, Goto K, Ochiai A, Ishii G.
- Journal Title
  
  Sci Rep.
  
  Volume: Apr 21;7:46662 Issue: 1 Pages: 1-13
- DOI
  10.1038/srep46662
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05311
[Journal Article] Immunohistochemical and genetic characteristics of lung cancer mimicking organizing pneumonia2017
- Author(s)
  T.Ichikawa, K.Saruwatari, S.Mimaki, M.Sugano, K.Aokage, M.Kojima, T.Hishida, S.Fujii, J.Yoshida, T.Kuwata, A.Ochiai, K.Suzuki, M.Tsuboi, K.Goto, K.Tsuchihara, G.Ishii,
- Journal Title
  
  Lung Cancer
  
  Volume: 113 Pages: 134-139
- DOI
  10.1016/j.lungcan.2017.10.001
- Peer Reviewed
- Data Source
  KAKENHI-INTERNATIONAL-15K21716, KAKENHI-PLANNED-26108007
[Journal Article] Clinicopathological significance of caveolin-1 expression by cancer-associated fibroblasts in lung adenocarcinoma2017
- Author(s)
  K.Shimizu, K.Kirita, K.Aokage, M.Kojima, T.Hishida, T.Kuwata, S.Fujii, A.Ochiai, K.Funai, J.Yoshida, M.Tsuboi, G.Ishii
- Journal Title
  
  Journal of Cancer Research and Clinical Oncology
  
  Volume: 143 Issue: 2 Pages: 321-328
- DOI
  10.1007/s00432-016-2285-2
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-26108007, KAKENHI-PROJECT-16K10699
[Journal Article] Clinical and pathological staging validation in the eighth edition of the TNM classification for lung cancer: Correlation between solid size on thin-section computed tomography and invasive size in pathological findings in the new T classification2017
- Author(s)
  K.Aokage, T.Miyoshi, G.Ishii, M.Kusumoto, S.Nomura, S.Katsumata, K.Sekihara, T.Hishida, M.Tsuboi
- Journal Title
  
  Journal of Thoracic Oncology
  
  Volume: 12 Issue: 9 Pages: 1403-1412
- DOI
  10.1016/j.jtho.2017.06.003
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-26108007
[Journal Article] Changes in the tumor microenvironment during lymphatic metastasis of lung squamous cell carcinoma2017
- Author(s)
  S.Ikemura, N.Aramaki, S.Fujii, K.Kirita, S.Umemura, S.Matsumoto, K.Yoh, S.Niho, H.Ohmatsu, T.Kuwata, M.Kojima, A.Ochiai, T.Betsuyaku, M.Tsuboi, K.Goto, G.Ishii
- Journal Title
  
  Cancer Science
  
  Volume: 108 Issue: 1 Pages: 136-142
- DOI
  10.1111/cas.13110
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-26108007
[Journal Article] Aggressive tumor microenvironment of solid predominant lung adenocarcinoma subtype harboring with epidermal growth factor receptor mutations2016
- Author(s)
  K.Saruwatari, S.Ikemura, K.Sekihara, T.Kuwata, S.Fujii, S.Umemura, K.Kirita, S.Matsumoto, K.Yoh, S.Niho, H.Ohmatsu, A.Ochiai, H.Kohrogi, M.Tsuboi, K.Goto, G.Ishii
- Journal Title
  
  Lung Cancer
  
  Volume: 91 Pages: 7-14
- DOI
  10.1016/j.lungcan.2015.11.012
- Peer Reviewed
- Data Source
  KAKENHI-INTERNATIONAL-15K21716, KAKENHI-PLANNED-26108007
[Journal Article] Microenvironmental changes in the progression from adenocarcinoma in situ to minimally invasive adenocarcinoma and invasive lepidic predominant adenocarcinoma of the lung2016
- Author(s)
  M.Naito, K.Aokage, K.Saruwatari, K.Hisakane, T.Miyoshi, T.Hishida, J.Yoshida, S.Masato, M.Kojima, T.Kuwata, S.Fujii, A.Ochiai, Y.Sato, M.Tsuboi, G.Ishii
- Journal Title
  
  Lung Cancer
  
  Volume: 100 Pages: 53-62
- DOI
  10.1016/j.lungcan.2016.07.024
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-26108007, KAKENHI-PROJECT-16K10699
[Journal Article] Therapeutic Priority of the PI3K/AKT/mTOR Pathway in Small Cell Lung Cancers as Revealed by a Comprehensive Genomic Analysis.2014
- Author(s)
  Umemura S, Mimaki S, Makinoshima H, Tada S, Ishii G, Ohmatsu H, Niho S, Yoh K, Matsumoto S, Takahashi A, Morise M, Nakamura Y, Ochiai A, Nagai K, Iwakawa R, Kohno T, Yokota J, Ohe Y, Esumi H, Tsuchihara K, Goto K.
- Journal Title
  
  J Thorac Oncol
  
  Volume: 9(9) Issue: 9 Pages: 1324-31
- DOI
  10.1097/jto.0000000000000250
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24300346
[Journal Article] Podoplanin-positive cancer associated fibroblast could have prognostic value independent of cancer cell phenotype in stage I lung squamous cell carcinoma: Utility of combining analysis of both cancer cell phenotype and cancer associated fibroblast phenotype.2013
- Author(s)
  Ono S, Ishii G*, Nagai K, Takuwa T, Yoshida J, Nishimura M, Hishida T, Aokage K Fujii S, Ikeda N, Ochiai A.
- Journal Title
  
  Chest
  
  Volume: 143(4) Pages: 963-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659185
[Journal Article] Identification of prognostic immunophenotypic features in cancer stromal cells of high-grade neuroendocrine carcinomas of the lung.2013
- Author(s)
  Takahashi A, Ishii G*, Kinoshita T, Yoshida T, Umemura S, Hishida T, Yoh K, Niho S, Goto K, Ohmatsu H, Ohe Y, Nagai K, Ochiai A.
- Journal Title
  
  J Cancer Res Clin Oncol.
  
  Volume: 139(11) Issue: 11 Pages: 1869-78
- DOI
  10.1007/s00432-013-1502-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659185
[Journal Article] Identification of prognostic immunophenotypic features in cancer stromal cells of high-grade neuroendocrine carcinomas of the lung2013
- Author(s)
  Takahashi A, Ishii G, Kinoshita T, Yoshida T, Umemura S, Hishida T, Yoh K, Niho S, Goto K, Ohmatsu H, Ohe Y, Nagai K, Ochiai A.
- Journal Title
  
  J Cancer Res Clin Oncol
  
  Volume: 139(11) Pages: 1869-78
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659185
[Journal Article] Podoplanin-positive cancer associated fibroblast could have prognostic value independent of cancer cell phenotype in stage I lung squamous cell carcinoma: Utility of combining analysis of both cancer cell phenotype and cancer associated fibroblast phenotype.2013
- Author(s)
  Ono S, Ishii G*, Nagai K, Takuwa T, Yoshida J, Nishimura M, Hishida T, Aokage K Fujii S, Ikeda N, Ochiai A
- Journal Title
  
  Chest
  
  Volume: 2013, Apr;143(4) Pages: 963-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659185
[Journal Article] Podoplanin-positive cancer associated fibroblast could have prognostic value independent of cancer cell phenotype in stage I lung squamous cell carcinoma : Utility of combining analysis of both cancer cell phenotype and cancer associated fibroblast phenotype2013
- Author(s)
  Ono S, Ishii G, Nagai K, Takuwa T, Yoshida J, Nishimura M, Hishida T, Aokage K Fujii S, Ikeda N, Ochiai A.
- Journal Title
  
  Chest
  
  Volume: 143(4) Pages: 963-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659185
[Journal Article] Forkhead box P3 regulatory T cells coexisting with cancer associated fibroblasts are correlated with a poor outcome in lung adenocarcinoma.2013
- Author(s)
  Kinoshita T
- Journal Title
  
  Cancer Sci.
  
  Volume: 104 Issue: 4 Pages: 409-415
- DOI
  10.1111/cas.12099
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390469, KAKENHI-PROJECT-24659185
[Journal Article] Prognostic significance of cancer associated stromal cells in stage I lung adenocarcinoma patients2012
- Author(s)
  Itoh M, Ishii G, Nagai K, Maeda R, Nakano Y, Ochiai A.
- Journal Title
  
  Chest
  
  Volume: 142(1) Pages: 151-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659185
[Journal Article] Recruitment of podoplanin positive cancer-associated fibroblasts in metastatic lymph nodes predicts poor prognosis in pathological N2 Stage III lung adenocarcinoma2012
- Author(s)
  Neri S, Ishii G,Taira T, Hishida T,Yoshida J, Nishimura M, Nagai K, Ochiai A.
- Journal Title
  
  Ann. Surg. Oncol
  
  Volume: 19(12) Pages: 3953-62
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659185
[Journal Article] Prognostic significance of cancer associated stromal cells in stage I lung adenocarcinoma patients.2012
- Author(s)
  Itoh M, Ishii G*, Nagai K, Maeda R, Nakano Y, Ochiai A.
- Journal Title
  
  Chest
  
  Volume: Jul;142(1):151-8 Issue: 1 Pages: 151-158
- DOI
  10.1378/chest.11-2458
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659185
[Journal Article] Tumor promoting effect of podoplanin-positive fibroblasts is mediated by enhanced RhoA activity2012
- Author(s)
  Ito S, Ishii G, Hoshino A, Hashimoto H, Neri S, Kuwata T, Higashi M, Nagai K, Ochiai A.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 422(1) Pages: 194-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659185
[Journal Article] Tumor promoting effect of podoplanin-positive fibroblasts is mediated by enhanced RhoA activity.2012
- Author(s)
  Ito S, Ishii G, Hoshino A, Hashimoto H, Neri S, Kuwata T, Higashi M, Nagai K, Ochiai A.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 442 Issue: 1 Pages: 194-9
- DOI
  10.1016/j.bbrc.2012.04.158
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590413, KAKENHI-PROJECT-24659185
[Journal Article] Dynamic molecular changes associated with epithelial-mesenchymal transition and subsequent mesenchymal-epithelial transition in the early phase of metastatic tumor formation.2011
- Author(s)
  Aokage K, Ishii G, Ohtaki Y, Yamaguchi Y, Hishida T, Yoshida J, Nishimura M, Nagai K, Ochiai A
- Journal Title
  
  Int J Cancer. 128(7)
  
  Pages: 1585-95
- Data Source
  KAKENHI-PROJECT-20590417
[Journal Article] Dynamic molecular changes associated with epithelial-mesenchymal transition and subsequent mesenchymal-epithelial transition in the early phase of metastatic tumor formation.2011
- Author(s)
  Aokage, K, Ishii G, et al.
- Journal Title
  
  Int.J.Cancer
  
  Volume: 128(7) Pages: 1585-1595
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590417
[Journal Article] Nerve invasion distance is dependent on laminin gamma2 in tumors of pancreatic cancer.2010
- Author(s)
  Mitsunaga S, Ishii G, et al.
- Journal Title
  
  Int.J.Cancer
  
  Volume: 127(4) Pages: 805-819
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590417
[Journal Article] Histopathological features of the tumor budding in adenocarcinoma of the lung : Tumor budding as an index to predict the potential aggressiveness.2010
- Author(s)
  Yamaguchi Y, Ishii G, et al.
- Journal Title
  
  J Thorac Oncol.
  
  Volume: 5(9) Pages: 1361-1368
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590417
[Journal Article] Fibroblasts associated with cancer cells keep enhanced migration activity after separation from cancer cells : a novel character of tumor educated fibroblasts.2010
- Author(s)
  Ishii G, Hashimoto H, Asada K, Ito T, Hoshino A, Fujii S, Kojima M, Kuwata T, Harigaya K, Nagai K, Ushijima T, Ochiai A
- Journal Title
  
  Int J Oncol. 37(2)
  
  Pages: 317-25
- Data Source
  KAKENHI-PROJECT-20590417
[Journal Article] Stromal Macrophage Expressing CD204 Is Associated with Tumor Aggressiveness in Lung Adenocarcinoma.2010
- Author(s)
  Ohtaki Y, Ishii G, et al.
- Journal Title
  
  J Thorac Oncol
  
  Volume: 5(10) Pages: 1507-1515
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590417
[Journal Article] Extratumoral vascular invasion is a significant prognostic indicator and apredicting factor of distant metastasis in non-small cell lung cancer.2010
- Author(s)
  Shimada Y, Ishii G, et al.
- Journal Title
  
  J Thorac Oncol
  
  Volume: 5(7) Pages: 970-975
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590417
[Journal Article] Histopathologic Features of the Tumor Budding in Adenocarcinoma of the Lung : Tumor Budding As an Index to Predict the Potential Aggressiveness.2010
- Author(s)
  Yamaguchi Y, Ishii G, Kojima M, Yoh K, Otsuka H, Otaki Y, Aokage K, Yanagi S, Nagai K, Nishiwaki Y, Ochiai A
- Journal Title
  
  J Thorac Oncol. 5(9)
  
  Pages: 1361-8
- Data Source
  KAKENHI-PROJECT-20590417
[Journal Article] Stromal macrophage expressing CD204 is associated with tumor aggressiveness in lung adenocarcinoma.2010
- Author(s)
  Ohtaki Y, Ishii G, Nagai K, Ashimine S, Kuwata T, Hishida T, Nishimura M, Yoshida J, Takeyoshi I, Ochiai A
- Journal Title
  
  J Thorac Oncol. 5(10)
  
  Pages: 1507-15
- Data Source
  KAKENHI-PROJECT-20590417
[Journal Article] CD133 expression in rectal cancer after preoperative chemoradiotherapy.2010
- Author(s)
  Kojima M, Ishii G, et al.
- Journal Title
  
  Cancer Sci.
  
  Volume: 101(4) Pages: 906-912
- NAID
  10026590792
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590417
[Journal Article] Fibroblasts associated with cancer cells keep enhanced migration activity after separation from cancer cells ; A novel character of tumor educated fibroblasts.2010
- Author(s)
  Ishii G, et al.
- Journal Title
  
  Int.J.Oncol.
  
  Volume: 37(2) Pages: 317-325
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590417
[Journal Article] A novel histopathological evaluation method predicting the outcome of non-small cell lung cancer treated by neoadjuvant therapy : The prognostic importance of the area of residual tumor.2010
- Author(s)
  Yamane Y, Ishii G, et al.
- Journal Title
  
  J.Thorac Oncol.
  
  Volume: 5(1) Pages: 49-55
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590417
[Journal Article] A novel histopathological evaluation method predicting the outcome of non-small cell lung cancer treated by neoadjuvant therapy : the prognostic importance of the area of residual tumor.2010
- Author(s)
  Yamane Y, Ishii G, Goto K, Kojima M, Nakao M, Shimada Y, Nishiwaki Y, Nagai K, Kohrogi H, Ochiai A
- Journal Title
  
  J Thorac Oncol. 5(1)
  
  Pages: 49-55
- Data Source
  KAKENHI-PROJECT-20590417
[Journal Article] Prognostic significance of carbonic anhydrase IX expression by cancer-associated fibroblasts in lung adenocarcinoma.2009
- Author(s)
  Nakao M, Ishii G, Nagai K, Kawase A, Kenmotsu H, Kon-No H, Hishida T, Nishimura M, Yoshida J, Ochiai A
- Journal Title
  
  Cancer. 115(12)
  
  Pages: 2732-43
- Data Source
  KAKENHI-PROJECT-20590417
[Journal Article] Improvement of the breaking strength of wound by combined treatment with recombinant human G-CSF, recombinant human M-CSF, and a TGF-beta1 receptor kinase inhibitor in rat skin.2008
- Author(s)
  Sugiyama K, Ishii G, Ochiai A, Esumi H
- Journal Title
  
  Cancer Sci. 99(5)
  
  Pages: 1021-8
- Data Source
  KAKENHI-PROJECT-20590417
[Journal Article] Podoplanin expression by cancer associated fibroblasts predicts poor prognosis of lung adenocarcinoma.2008
- Author(s)
  Kawase A, Ishii G, Nagai K, Ito T, Nagano T, Murata Y, Hishida T, Nishimura M, Yoshida J, Suzuki K, Ochiai A
- Journal Title
  
  Int J Cancer. 123(5)
  
  Pages: 1053-9
- Data Source
  KAKENHI-PROJECT-20590417
[Journal Article] Human vascular adventitial fibroblasts contain mesenchymal stem/progenitor cells.2008
- Author(s)
  Hoshino A, Chiba H, Nagai K, Ishii G, Ochiai A
- Journal Title
  
  Biochem Biophys Res Commun 368
  
  Pages: 305-310
- Data Source
  KAKENHI-PROJECT-20590417
[Journal Article] CD105-positive cells in pulmonary arterial blood of adult human lung cancer patients include mesenchymal progenitors.2008
- Author(s)
  Chiba H, Ishii G, Ito TK, Aoyagi K, Sasaki H, Nagai K, Ochiai A
- Journal Title
  
  Stem Cells. 26(10)
  
  Pages: 2523-30
- Data Source
  KAKENHI-PROJECT-20590417
[Journal Article] Carbonic anhydrase IX expression in associated with tumor progression and a poor prognosis of lung adenocarcinoma.2006
- Author(s)
  Kon-no H, Ishii G et al.
- Journal Title
  
  Lung Cancer. 54(3):
  
  Pages: 409-18
- Data Source
  KAKENHI-PROJECT-17590366
[Journal Article] Differences in clinicopathological and biological features between central-type and peripheral-type squamous cell carcinoma of the lung.2006
- Author(s)
  Saijo T, Ishii G et al.
- Journal Title
  
  Lung Cancer. 52(1):
  
  Pages: 37-45
- Data Source
  KAKENHI-PROJECT-17590366
[Journal Article] Hormonal stimulation increases the recruitment of bone marrow-derived myoepithelial cells and periductal fibroblasts into the mammary gland.2006
- Author(s)
  Sangai T, Ishii G et al.
- Journal Title
  
  Biochem Biophys Res Commun 346(4):
  
  Pages: 1173-80
- Data Source
  KAKENHI-PROJECT-17590366
[Journal Article] Immunohistochemical prognostic factors in resected colorectal lung metastases using tissue microarray analysis.2006
- Author(s)
  Shiono S, Ishii G et al.
- Journal Title
  
  Eur J Surg Oncol 32(3):
- Data Source
  KAKENHI-PROJECT-17590366
[Journal Article] Immunohistochemical differential diagnosis between large cell neuroendocrine carcinoma and small cell carcinoma by tissue microarray analysis with a large antibody panel2006
- Author(s)
  Nitadori J, Ishii G et al.
- Journal Title
  
  Am J Clin Pathol. 125(5):
  
  Pages: 682-92
- Data Source
  KAKENHI-PROJECT-17590366
[Journal Article] Inhibition of Bone-Derived Insulin-like Growth Factors by a Ligand Specific Antibody Suppresses the Growth of Human Multiple Myeloma in the Human Adult Bone explanted in NOD/SCID mouse.2006
- Author(s)
  Araki K, Ishii G et al.
- Journal Title
  
  Int. J. Cancer 118(10)
  
  Pages: 2602-8
- Data Source
  KAKENHI-PROJECT-17590366
[Journal Article] Effect of differences in cancer cells and tumor growth sites on recruiting bone marrow-derived endothelial cells and myofibroblasts in cancer-induced stroma.2005
- Author(s)
  Sangai T, Ishii G, et. al.
- Journal Title
  
  Int.J.Cancer. 115(6)
  
  Pages: 885-92
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590366
[Journal Article] Effect of differences in cancer cells and tumor growth sites on recruiting bone marrow-derived endothelial cells and myofibroblasts in cancer-induced stroma.2005
- Author(s)
  Sangai T, Ishii G., et. al.
- Journal Title
  
  Int. J Cancer 115(6)
  
  Pages: 885-92
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590366
[Journal Article] Expression and localization of mRNAs for matrix metalloproteinases and their inhibitors in mixed bronchioloalveolar carcinomas with invasive components.2005
- Author(s)
  Kanomata N, Ishii G, et al.
- Journal Title
  
  Mod Pathol. (Advance on line publication.)
- Data Source
  KAKENHI-PROJECT-15590359
[Journal Article] In vivo immunophenotype of bone-marrow-derived fibroblasts recruited into fibrotic lesions.2005
- Author(s)
  Ishii G., et. al.
- Journal Title
  
  Stem cells 23(5)
  
  Pages: 699-706
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590366
[Journal Article] Laminin 5 expression protects against anoikis at aerogenous spread and lepidic growth of human lung adenocarcinoma.2005
- Author(s)
  Kodama K, Ishii G et al.
- Journal Title
  
  Int.J Cancer. 116(6)
  
  Pages: 876-884
- Data Source
  KAKENHI-PROJECT-17590366
[Journal Article] Effect of differences in cancer cells and tumor growth sites on recruiting bone marrow-derived endothelial cells and myofibroblasts in cancer-induced stroma.2005
- Author(s)
  Sangai T, Ishii G, et al.
- Journal Title
  
  Int. J Cancer. (Advance on line publication)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590359
[Journal Article] Blockade of paracrine supply of insulin-like growth factors using neutralizing antibodies suppresses the liver metastasis of human colorectal cancers.2005
- Author(s)
  Miyamoto S, Ishii G. et al.
- Journal Title
  
  Clin Cancer Res. 11(9)
  
  Pages: 3494-3502
- Data Source
  KAKENHI-PROJECT-17590366
[Journal Article] In vivo immunophenotype of bone-marrow-derived fibroblasts recruited into fibrotic lesions.2005
- Author(s)
  Ishii G, Ochiai A, et al.
- Journal Title
  
  Stem cells. (In press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590359
[Journal Article] Primary tumour-vessel tumour-nodal tumour classification for patients with invasive ductal carcinoma of the breast.2005
- Author(s)
  Hasebe T, Ishii G, et al.
- Journal Title
  
  Br J Cancer. 92
  
  Pages: 847-856
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590359
[Journal Article] In vivo and in vitro characterization of human fibroblast recruited selectively into human cancer stroma.2005
- Author(s)
  Ishii G, et. al.
- Journal Title
  
  Int.J.Cancer. 117(2)
  
  Pages: 212-220
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590366
[Journal Article] Primary tumour-vessel tumour-nodal tumour classification for patients with invasive ductal carcinoma of the breast.2005
- Author(s)
  Hasebe T, Ishii G. et al.
- Journal Title
  
  Br J Cancer. 92(5)
  
  Pages: 847-856
- Data Source
  KAKENHI-PROJECT-17590366
[Journal Article] In vivo and in vitro characterization of human fibroblast recruited selectively into human cancer stroma.2005
- Author(s)
  Ishii G, Ochiai A, et al.
- Journal Title
  
  Int.J Cancer. (In press)
- Data Source
  KAKENHI-PROJECT-15590359
[Journal Article] In vivo and in vitro characterization of human fibroblast recruited selectively into human cancer stroma.2005
- Author(s)
  Ishii G, Ochiai A, et al.
- Journal Title
  
  Int. J Cancer. (In press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590359
[Journal Article] Primary Lung Adenocarcinoma with Massive Lymphocyte Infiltration.2005
- Author(s)
  Tsuta K, Ishii G, et al.
- Journal Title
  
  Am J Clin Pathol. 123
  
  Pages: 1-6
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590359
[Journal Article] In vivo and in vitro characterization of human fibroblast recruited selectively into human cancer stroma.2005
- Author(s)
  Ishii G., et. al.
- Journal Title
  
  Int. J Cancer 117(2)
  
  Pages: 212-20
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590366
[Journal Article] In vivo and in vitro characterization of human fibroblast recruited selectively into human cancer stroma.2005
- Author(s)
  Ishii G, et al.
- Journal Title
  
  Int.J.Cancer. 117(2)
  
  Pages: 212-220
- Data Source
  KAKENHI-PROJECT-17590366
[Journal Article] Effect of differences in cancer cells and tumor growth sites on recruiting bone marrow-derived endothelial cells and myofibroblasts in cancer-induced stroma.2005
- Author(s)
  Sangai T, Ishii G, et al.
- Journal Title
  
  Int.J Cancer. (Advance on line publication.)
- Data Source
  KAKENHI-PROJECT-15590359
[Journal Article] In vivo immunophenotype of bone-marrow-derived fibroblasts recruited into fibrotic lesions.2005
- Author(s)
  Ishii G, et al.
- Journal Title
  
  Stem cells. 23(5)
  
  Pages: 699-706
- Data Source
  KAKENHI-PROJECT-17590366
[Journal Article] Laminin 5 expression protects against anoikis at aerogenous spread and lepidic growth of human lung adenocarcinoma.2005
- Author(s)
  Kodama K, Ishii G., et. al.
- Journal Title
  
  Int. J Cancer 116(6)
  
  Pages: 876-84
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590366
[Journal Article] In vivo immunophenotype of bone-marrow-derived fibroblasts recruited into fibrotic lesions.2005
- Author(s)
  Ishii G, et. al.
- Journal Title
  
  Stem cells. 23(5)
  
  Pages: 699-706
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590366
[Journal Article] Effect of differences in cancer cells and tumor growth sites on recruiting bone marrow-derived endothelial cells and myofibroblasts in cancer-induced stroma.2005
- Author(s)
  Sangai T, Ishii G et al.
- Journal Title
  
  Int.J.Cancer. 115(6)
  
  Pages: 885-892
- Data Source
  KAKENHI-PROJECT-17590366
[Journal Article] Expression and localization of mRNAs for matrix metalloproteinases and their inhibitors in mixed bronchioloalveolar carcinomas with invasive components.2005
- Author(s)
  Kanomata N, Ishii G, et al.
- Journal Title
  
  Mod Pathol. (Advance on line publication)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590359
[Journal Article] Low levels of insulin-like growth factor type 1 receptor expression at cancer cell membrane predict liver metastasis in Dukes' C human colorectal cancers.2004
- Author(s)
  Nakamura M, Ishii G, et al.
- Journal Title
  
  Clin Cancer Res. 10
  
  Pages: 8434-8441
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590359
[Journal Article] Growth inhibition of human prostate cancer cells in human adult bone implanted into nonobese diabetic/severe combined immunodeficient mice by a ligand-specific antibody to human insulin-like growth factors.2004
- Author(s)
  Goya M, Ishii G, et al.
- Journal Title
  
  Cancer Res. 64
  
  Pages: 6252-6258
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590359
[Journal Article] Topographical distribution of allelic loss in individual lung adenocarcinomas with lymph node metastases.2004
- Author(s)
  Yoshikawal T, Ishii G, et al.
- Journal Title
  
  Mod Pathol. 17
  
  Pages: 204-213
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590359
[Journal Article] Nuclear beta-catenin accumulation as a prognostic factor in Dukes' D human colorectal cancers.2004
- Author(s)
  Miyamaoto S, Ishii G, et al.
- Journal Title
  
  Oncol Rep. 12
  
  Pages: 245-251
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590359
[Journal Article] Matrix Metalloproteinase-7 Facilitates Insulin-Like Growth Factor Bioavailability through Its Proteinase Activity on Insulin-Like Growth Factor Binding Protein 3.2004
- Author(s)
  Miyamaoto S, Ishii G, et al.
- Journal Title
  
  Cancer Res. 64
  
  Pages: 665-671
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590359
[Journal Article] Low levels of insulin-like growth factor type 1 receptor expression at cancer cell membrane predict liver metastasis in Dukes'C human colorectal cancers.2004
- Author(s)
  Nakamura M, Ishii G, et al.
- Journal Title
  
  Clin Cancer Res. 10
  
  Pages: 8434-8441
- Data Source
  KAKENHI-PROJECT-15590359
[Journal Article] Dominant papillary subtype is a significant predictor of the response to gefitinib in adenocarcinoma of the lung.2004
- Author(s)
  Kim YH, Ishii G, et al.
- Journal Title
  
  Clin.Cancer Res. 10
  
  Pages: 7311-7317
- Data Source
  KAKENHI-PROJECT-15590359
[Journal Article] Predictive Markers for Late Cervical Metastasis in Stage I and II Invasive Squamous Cell Carcinoma of the Oral Tongue.2004
- Author(s)
  Lim SC, Ishii G, et al.
- Journal Title
  
  Clin Cancer Res. 10
  
  Pages: 166-172
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590359
[Journal Article] Breast Cancer Resistance Protein Impacts Clinical Outcome in Platinum-based Chemotherapy for Advanced Non-Small Cell Lung Cancer.2004
- Author(s)
  Yoh K, Ishii G, et al.
- Journal Title
  
  Clin Cancer Res. 10
  
  Pages: 1691-1697
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590359
[Journal Article] Primary Lung Carcinoma With Signet-ring Cell Carcinoma Components : Clinicopathological Analysis of 39 Cases.2004
- Author(s)
  Tsuta K, Ishii G, et al.
- Journal Title
  
  Am J Surg Pathol. 28
  
  Pages: 868-874
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590359
[Journal Article] Nuclear beta-catenin accumulation as a prognostic factor in Dukes'D human colorectal cancers.2004
- Author(s)
  Miyamaoto S, Ishii G, et al.
- Journal Title
  
  Oncol Rep. 12
  
  Pages: 245-251
- Data Source
  KAKENHI-PROJECT-15590359
[Journal Article] Dominant papillary subtype is a significant predictor of the response to gefitinib in adenocarcinoma of the lung.2004
- Author(s)
  Kim YH, Ishii G, et al.
- Journal Title
  
  Clin. Cancer Res. 10
  
  Pages: 7311-7317
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590359
[Journal Article] Bone-marrow-derived myofibroblasts contribute to the cancer-induced stromal reaction.2003
- Author(s)
  Ishii G, Ochiai A et al.
- Journal Title
  
  Biochem Biophys Res Commun. 309
  
  Pages: 232-240
- Data Source
  KAKENHI-PROJECT-15590359
[Journal Article] Intratumor Microvessel Density in Biopsy Specimens Predicts Local Response of Hypopharyngeal Cancer to Radiotherapy.2003
- Author(s)
  Zhang SC, Ishii G, et al.
- Journal Title
  
  Jpn J Clin Oncol. 33
  
  Pages: 613-619
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590359
[Journal Article] Bone-marrow-derived myofibroblasts contribute to the cancer-induced stromal reaction.2003
- Author(s)
  Ishii G, Ochiai A, et al.
- Journal Title
  
  Biochem Biophys Res Commun. 309
  
  Pages: 232-240
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590359
[Presentation] LC-SCRUMコホートを用いたICI反応予測における形態学的バイオマーカーの意義2024
- Author(s)
  元井紀子石井源一郎滝哲郎亜森グランバル永田真莉乃村上千明葉清隆後藤功一喜友名朝春神田浩明
- Organizer
  第１１３回日本病理学会学術集会
- Data Source
  KAKENHI-PROJECT-21K06900
[Presentation] 造影3次元CT画像による肺内・肺門・縦隔リンパ節の深層学習を用いたセグメンテーション2023
- Author(s)
  河田佳樹, 松元祐司, 土田敬明, 青景圭樹, 石井源一郎, 楠本昌彦, 仁木登
- Organizer
  第14回呼吸機能イメージング研究会学術集会
- Data Source
  KAKENHI-PROJECT-20H04551
[Presentation] A human-in-the-loop workflow for thoracic lymph nodes annotation using contrast-enhanced CT images2023
- Author(s)
  Yoshiki Kawata, Yuji Matsumoto, Takaaki Tsuchida, Keiju Aokage, Genichiro Ishii, Masahiro Kusumoto, Noboru Nik
- Organizer
  International Forum On Medical Imaging In Asia 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H04551
[Presentation] 拡大CT画像を用いた肺腺がん(病期IA)のコンピュータ支援予後予測2019
- Author(s)
  河田佳樹, 仁木登, 楠本昌彦, 大松広伸, 青景圭樹, 石井源一郎, 土田敬明, 松元裕司, 江口研二, 金子昌弘
- Organizer
  第11回呼吸機能イメージング研究会学術集会
- Data Source
  KAKENHI-PLANNED-26108007
[Presentation] Prognostic importance of pleural attachment status measured by pretreatment CT images in patients with stage IA lung adenocarcinoma: measurement of the ratio of the interface between nodule and neighboring pleura to nodule surface area2018
- Author(s)
  Y.Kawata, N.Niki, M.Kusumoto, H.Ohmatsu, K.Aokage, G.Ishii, Y.Matsumoto, T.Tsuchida, K.Eguchi, M.Kaneko
- Organizer
  Proc.SPIE Medical Imaging
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26108007
[Presentation] 拡大CT画像を用いた肺がんのコンピュータ支援予後予測：肺腺がん（病期IA）の周囲既存構造と再発リスクの関連2018
- Author(s)
  河田佳樹，仁木登，楠本昌彦，大松広伸，青景圭樹，石井源一郎，土田敬明，松元祐司，江口研二，金子昌弘
- Organizer
  第10回呼吸機能イメージング研究会学術集会
- Data Source
  KAKENHI-PLANNED-26108007
[Presentation] 免疫・がん・微小環境のクロストークがん進展に寄与するCancer associated fibroblasts(CAFs)の病理生物像の解析2013
- Author(s)
  石井源一郎,祢里真也,吉田達哉,落合淳志
- Organizer
  日本病理学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24659185
[Presentation] 肺腺癌における間質へ浸潤する制御性T細胞の意義2012
- Author(s)
  木下智成,石井源一郎,平岡伸介,青景圭樹,菱田智之,吉田純司,永井完治,落合淳志
- Organizer
  日本癌学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24659185
[Presentation] 神経内分泌腫瘍で過剰発現するPTPRZ1の肺小細胞がん進展における機能解析2012
- Author(s)
  牧野嶋秀樹,石井源一郎,小嶋基寛,藤井誠志,桑田健,落合淳志
- Organizer
  日本癌学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24659185
[Presentation] 大腸がんの転移を促進する漿膜直下微小環境の特徴2012
- Author(s)
  小嶋基寛,石井源一郎,牧野嶋秀樹,樋口洋一,斎藤典男,落合淳志
- Organizer
  日本癌学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24659185
[Presentation] 腫瘍微小環境の病理病態がん関連線維芽細胞が、がん進展に及ぼす病態病理機構2012
- Author(s)
  石井源一郎,祢里真也,落合淳志
- Organizer
  日本癌学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24659185

1. OCHIAI Atsushi (60183034)

# of Collaborated Projects: 3 results

# of Collaborated Products: 15 results
2. HARIGAYA Kenichi (40101894)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. Niki Noboru (80116847)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
4. KAWATA Yoshiki (70274264)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
5. TAMARU Junichi (30188429)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 楠本昌彦 (90252767)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
7. 青景圭樹 (20544753)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
8. 松元祐司 (00600579)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
9. GOTO Koichi (90435719)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. UMEMURA Shigeki (80623967)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. TSUCHIHARA Katsuya (00415514)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. ESUMI Hiroyasu (70160364)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. Tatsuya ODA (20282353)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. HIRABAYASHI Jun (40156691)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. OHKOHCHI Nobuhiro (40213673)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 岸宏久 (90323394)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 北川元生 (40262026)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 東守洋 (00323395)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
19. 鈴木秀宣 (50546710)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
20. 島田光生 (10216070)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 原田雅史 (20228654)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 安倍正博 (80263812)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 井本逸勢 (30258610)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 梅谷啓二 (50344396)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 飯沼元 (60222824)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 中野恭幸 (00362377)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 阪井宏彰 (50362489)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 大松広伸 (40415518)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
29. 三嶋理晃 (60190625)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 三方淳男 (40051289)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 菅野雅人 (40643606)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 石橋昌幸 (80763630)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
33. 木田泰之 (20396526)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 舘野浩章 (30450670)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 土田敬明 (80256239)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
36. 中井登紀子 (00619538)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. 元井紀子 (70292878)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
38. 吉田達哉 (10729338)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. 大江裕一郎 (20233041)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. 白澤昌之 (40898996)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. 青木一教 (60270675)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
42. 吉田裕 (70750751)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
43. 河野隆志 (80280783)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
44. 渡辺俊一 (80303303)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
45. 浜本隆二 (80321800)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
46. 神田浩明 (90260067)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
47. 横山昌幸 (20220577)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
48. 小松鉄平 (60723856)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
49. 松村保広 (90209619)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
50. SAKAMOTO Naoya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
51. 滝哲郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
52. 三好智博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
53. 坂下信悟

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ISHII Genichiro 石井 源一郎

Research Projects

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Co-Researchers

New frontiers of thrombolytic agents: Applications of a novel thrombolytic agent to acute and chronic cranial nerve diseases.

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Study of cancer-associated fibroblasts in tumor re-progression after chemotherapyPrincipal Investigator

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Development study on pathological predictive biomarkers for cancer treatment

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Quantitative diagnosis of early-stage lung cancer by fusing non-contrast and contrast high-definition CT images

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Fibroblast-dependent cancer cell invasionPrincipal Investigator

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CD200-positive cancer associated fibroblasts augment the sensitivity of Epidermal Growth Factor Receptor mutation-positive lung adenocarcinomas to EGFR Tyrosine kinase inhibitorsPrincipal Investigator

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iCAF: Cancer associated fibroblast derived from iPS cells and its surface glycan as a target of cancer therapy.

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Cancer Diagnosis and Prognosis Assistance Based on Multidisciplinary Computational Anatomy

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Comprehensive genomic analysis of small cell lung cancer exploring mechanisms of the proliferation and therapeutic targets

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Development of target therapy for stromal cellsPrincipal Investigator

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Mechanism of tumor promoting effect by mesenchymal progenitor cellPrincipal Investigator

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In vivo and in vitro characterization of bone-marrow derived fibroblast recruited into cancer induced stroma.Principal Investigator

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Characterization of bone-marrow derived fibroblast recruited into cancer induced stroma.Principal Investigator

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ISHII Genichiro 石井源一郎