Fukushima Takeshi 福島健

… Alternative Names

福島健フクシマタケシ

FUKUSHIMA Takeshi 福島健

FUKUSHIMA Takashi 福島健

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Researcher Number	00272485
Other IDs
Affiliation (Current)	2025: 東邦大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2021 – 2023: 東邦大学, 薬学部, 教授 2010 – 2019: 東邦大学, 薬学部, 教授 2006 – 2007: 静岡県立大学, 薬学部, 准教授 2003 – 2005: 静岡県立大学, 薬学部, 助教授 2002: 東京大学, 大学院・薬学系研究科, 講師 … More 1998 – 2000: 東京大学, 大学院・薬学系研究科, 助手 1997: The Univ.of Tokyo, Grad.School of Pharm.Sci., Research Associate, 薬学系研究科, 助手 1996: 東京大学, 薬学部, 助手 Less
Review Section/Research Field	Principal Investigator Medical pharmacy / Physical pharmacy / Basic Section 52010:General internal medicine-related / Laboratory medicine / 応用薬理学・医療系薬学 Except Principal Investigator Physical pharmacy / Integrated Nutrition Science / Physical pharmacy
Keywords	Principal Investigator マイクロダイアリシス / 統合失調症 / D-セリン / DBD-COCl / 精神病発症危険状態（ARMS） / ARMS / 精神病発症危険状態 / LC-MS/MS / ケタミン / 蛍光検出 … More / D-アミノ酸酸化酵素 / キヌレン酸 / カラムスイッチングHPLC / アナンダミド / 高分解能質量分析計 / メタボロミクス / プレカラム誘導体化試薬 / 有機酸 / 乳酸 / At-risk mental state / ヒト血清 / LC-MS / HPLC / グルタチオン / メチオニン / ホモシステイン / L-乳酸 / Microdialyysis / Fluorescence detection / Column-switching HPLC / N-acetylaspartic acid / Ketamine / Kvnurenine / Kynurenic acid / Schizophrenia / KAT / プロリン / セリン / グルタミン酸 / ラット脳マイクロダイアリシス / 光学異性体 / N-アセチルアスパラギン酸 / キヌレニン / microdialysis / Anandamide / ラット / β-シクロデキストリンポリマー / DBD-COC 1 / 第二世代抗精神病薬 / 第一世代抗精神病薬 / 9-ヒドロキシリスペリドン / リスペリドン / 分析科学 / 脳神経疾患 / D-アミノ酸酸化酵素(DAAO) / D-アミノ酸酸化酵素（DAAO） / 代謝 / D-トリプトファン / D-キヌレニン / DBD-COC1 / PMSF / NBD-COCl / DBD-COH_2 / DBD-PZ / 修飾セルロース型キラルカラム / 2-アリルプロピオン酸 … More Except Principal Investigator HPLC / NBD-F / benzofurazan / optical resolution / fluorimetric HPLC / fluorescent Edman reagent / Edman degradation / sequensor / PITC / ペプチドシークエンサー / 蛍光エドマン試薬 / ベンゾフラザン / 光学分割 / 蛍光-HPLC法 / エドマン分解 / シークエンサー / anti D-aspartate antibody / chiral stationary phase / pineal gland / D-aspartic acid / HPLCキラル固定相 / マイクロダイアリシス / 抗D-アスパラギン酸抗体 / 光学活性固定相 / 松果体 / D-アスパラギン酸 / 蛍光誘導体化法 / DBD-PyNCS / LCーMS / 蛍光誘導体化 / 多変量解析 / 遊離脂肪酸 / アミノ酸 / トリプトファン代謝物 / トリプトファン / 中枢性疾患 / 蛍光検出 / LC-MS / セロトニン / L-キヌレニン / Ｌｰトリプトファン / 統合失調症 / 中枢性精神疾患 / ヒル係数 / 結合定数 / 内分泌攪乱物質 / SRC1 / 転写共役因子 / Hill係数 / 内分泌撹乱物質 / エストロゲン受容体 / 蛍光偏光度 Less

Metabolomics of biomolecules in serum from individuals with at-risk mental state and first-episode psychosis: discovery of reliable marker to develop psychosisPrincipal Investigator
- Principal Investigator
  
  Fukushima Takeshi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Toho University
Analyses of metabolites in serum of individuals with ARMS and the development of the novel analytical method for diagnosis of ARMS.Principal Investigator
- Principal Investigator
  
  FUKUSHIMA Takeshi
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Toho University
Effect of antipsychotics on efficacy of D-serinePrincipal Investigator
- Principal Investigator
  
  FUKUSHIMA Takeshi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Toho University
Clinical research on the central nervous system disorder by quantitative determination of serum tryptophan metabolites
- Principal Investigator
  
  IIZUKA Hideaki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Integrated Nutrition Science
- Research Institution
  Toho University
Investigation on the production and/or metabolism of D-kynurenine in schizophreniaPrincipal Investigator
- Principal Investigator
  
  FUKUSHIMA Takeshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Toho University
Researches on the in vivo analyses of brain neurotransmitters in the animal model of schizophreniaPrincipal Investigator
- Principal Investigator
  
  FUKUSHIMA Takeshi
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  University of Shizuoka
蛍光偏光度測定による内分泌撹乱物質のスクリーニング法の開発
- Principal Investigator
  
  SANTA Tomofumi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Physical pharmacy
- Research Institution
  The University of Tokyo
in vivo analytical study on the endogenous agonist for cannabinoid receptor by using a microdialysis techniquePrincipal Investigator
- Principal Investigator
  
  FUKUSHIMA Takeshi
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  University of Shizuoka
  The University of Tokyo
カラムスイッチングHPLCによるアナンダミドおよび類縁体の高感度定量法の開発Principal Investigator
- Principal Investigator
  
  福島健
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Physical pharmacy
- Research Institution
  The University of Tokyo
Development of high-performance amino acid sequensor of peptides
- Principal Investigator
  
  IMAI Kazuhiro
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  The University of Tokyo
光学活性薬物のHPLCによる高感度光学分割検出法に関する研究Principal Investigator
- Principal Investigator
  
  福島健
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Physical pharmacy
- Research Institution
  The University of Tokyo
Studies on the establishment of the analytical method for, and the distribution and change of the total D-amino acids in mammalian body
- Principal Investigator
  
  IMAI Kazuhiro
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  The University of Tokyo

[Journal Article] Determination of D- and L-Amino Acids in Garlic Foodstuffs by Liquid Chromatography-Tandem Mass Spectrometry2023
- Author(s)
  Onozato Mayu、Nakanoue Haruna、Sakamoto Tatsuya、Umino Maho、Fukushima Takeshi
- Journal Title
  
  Molecules
  
  Volume: 28 Issue: 4 Pages: 1773-1773
- DOI
  10.3390/molecules28041773
- Data Source
  KAKENHI-PROJECT-21K07399
[Journal Article] Analyzing Citramalic Acid Enantiomers in Apples and Commercial Fruit Juice by Liquid Chromatography-Tandem Mass Spectrometry with Pre-Column Derivatization2023
- Author(s)
  Umino Maho、Onozato Mayu、Sakamoto Tatsuya、Koishi Mikoto、Fukushima Takeshi
- Journal Title
  
  Molecules
  
  Volume: 28 Issue: 4 Pages: 1556-1556
- DOI
  10.3390/molecules28041556
- Open Access
- Data Source
  KAKENHI-PROJECT-21K07399, KAKENHI-PROJECT-22K06733
[Journal Article] Preparation of imidazolidinone compounds as coupling reagent for diastereomerization and chromatographic separation of chiral organic acids2022
- Author(s)
  Maho Umino; Tatsuya Sakamoto; Mayu Onozato; Takeshi Fukushima
- Journal Title
  
  Journal of Chromatography A
  
  Volume: －
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07399
[Journal Article] Preparation of imidazolidinone compounds as derivatization reagent for diastereomerization and chromatographic separation of chiral organic acids2022
- Author(s)
  Umino Maho、Sakamoto Tatsuya、Onozato Mayu、Fukushima Takeshi
- Journal Title
  
  Journal of Chromatography A
  
  Volume: 1675 Pages: 463159-463159
- DOI
  10.1016/j.chroma.2022.463159
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07399, KAKENHI-PROJECT-22K06733
[Journal Article] Analyses of N-methyl-D-aspartate receptor-related metabolites in the serum of antipsychotic-naive individuals with at-risk mental state2020
- Author(s)
  Hiromi Tagata, Naohisa Tsujino, Mayu Onozato, Takahiro Nemoto, Takeshi Fukushima, Masafumi Mizuno
- Journal Title
  
  Toho Journal of Medicine
  
  Volume: -
- NAID
  120006884018
- Data Source
  KAKENHI-PROJECT-16K08944
[Journal Article] Serum D‐ and L‐lactate, pyruvate and glucose levels in individuals with at‐risk mental state and correlations with clinical symptoms2020
- Author(s)
  Onozato Mayu、Umino Maho、Shoji Ayako、Ichiba Hideaki、Tsujino Naohisa、Funatogawa Tomoyuki、Tagata Hiromi、Nemoto Takahiro、Mizuno Masafumi、Fukushima Takeshi
- Journal Title
  
  Early Intervention in Psychiatry
  
  Volume: - Issue: 4 Pages: 410-417
- DOI
  10.1111/eip.12866
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08944
[Journal Article] Alterations in methionine to homocysteine ratio in individuals with first-episode psychosis and those with at-risk mental state.2020
- Author(s)
  Onozato M, Uta A, Magarida A, Fukuoka N, Ichiba H, Tsujino N, Funatogawa T, Tagata H, Nemoto T, Mizuno M, Fukushima T
- Journal Title
  
  Clin Biochem.
  
  Volume: 77 Pages: 48-53
- DOI
  10.1016/j.clinbiochem.2019.12.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07175, KAKENHI-PROJECT-16K08944
[Journal Article] A high-performance liquid chromatography assay with a triazole-bonded column for evaluation of D-amino acid oxidase activity.2016
- Author(s)
  Iwasaki M, Kashiwaguma Y, Nagashima C, Izumi M, Uekusa A, Iwasa S, Onozato M, Ichiba H, Fukushima T
- Journal Title
  
  Biomedical Chromatography
  
  Volume: 30 Issue: 3 Pages: 384-389
- DOI
  10.1002/bmc.3559
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460224
[Journal Article] Evaluation of human D-amino acid oxidase inhibition by anti-psychotic drugs <i>in vitro </i>2014
- Author(s)
  Shishikura M, Hakariya H, Iwasa S, Yoshio T, Ichiba H, Yorita K, Fukui K, Fukushima T
- Journal Title
  
  BioScience Trends
  
  Volume: 8 Issue: 3 Pages: 149-154
- DOI
  10.5582/bst.2014.01034
- NAID
  130004572599
- ISSN
  1881-7815, 1881-7823
- Language
  English
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460224
[Journal Article] HPLC-fluorescence determination of thiol compounds in the serum of human male and female subjects using HILIC-mode column.2014
- Author(s)
  Kono Y, Iizuka H, Isokawa M, Tsunoda M, Ichiba H, Sadamoto K, Fukushima
- Journal Title
  
  Biomedical Chromatography
  
  Volume: 28 Issue: 5 Pages: 589-593
- DOI
  10.1002/bmc.3086
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23617027
[Journal Article] Determination of L-tryptophan and L-kynurenine in human serum by using LC-MS after derivatization with (R)-DBD-PyNCS2013
- Author(s)
  Ohashi H, Iizuka H, Yoshihara S, Otani H, Kume M, Sadamoto K, Ichiba H, Fukushima T
- Journal Title
  
  International Journal of Tryptophan Research
  
  Volume: 6 Pages: 9-14
- DOI
  10.4137/ijtr.s11459
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23617027
[Journal Article] Decreased L-tryptophan concentration in distinctive brain regions of mice treated repeatedly with phencyclidine2013
- Author(s)
  Iizuka H, Watanabe S, Koshikawa M, Matsumoto Y, Aoyama Y, Ichiba H, Nabeshima T, Fukushima T
- Journal Title
  
  Anal Bioanal Chem
  
  Volume: 405 Issue: 25 Pages: 8137-8141
- DOI
  10.1007/s00216-013-7010-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590147, KAKENHI-PROJECT-23617027
[Journal Article] Enantiomeric separation of tolperisone and eperisone by reversed-phase HPLC with cellulose tris(3-chloro-4-methylphenylcarbamate)-coated chiral column2013
- Author(s)
  Owada Y, Takahashi M, Iwasa S, Ichiba H, Sadamoto K, Fukushima T
- Journal Title
  
  Biomed Chromatogr
  
  Volume: 印刷中 Issue: 1 Pages: 102-105
- DOI
  10.1002/bmc.2892
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590147
[Journal Article] Development of a fluorescent chelating ligand for scandium ion having a Schiff base moiety2012
- Author(s)
  Yamada H, Kojo M, Nakahara T, Murakami K, Kakima T, Ichiba H, Yajima T, Fukushima T
- Journal Title
  
  Spectrochim Acta Part A
  
  Volume: 90 Pages: 72-77
- DOI
  10.1016/j.saa.2012.01.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590147
[Journal Article] A novel flow-injection analysis system for evaluation of antioxidants by using sodium dichloroisocyanurate as a source of hypochlorite anion2012
- Author(s)
  Ichiba H, Hanami K, Yagasaki K, Tanaka M, Ito H, Fukushima T
- Journal Title
  
  Drug Discoveries & Therapeutics
  
  Volume: 6 Issue: 1 Pages: 44-48
- DOI
  10.5582/ddt.2012.v6.1.44
- NAID
  130005054736
- ISSN
  1881-7831, 1881-784X
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590147
[Journal Article] Determination of N-acetylaspartic acid concentration in the mouse brain using HPLC with fluorescence detection2012
- Author(s)
  Song Z, Ge D, Ishii K, Yamada H, Toriumi K, Watanabe H, Nabeshima T, Fukushima T
- Journal Title
  
  Biomed Chromatogr
  
  Volume: 26 Issue: 2 Pages: 147-151
- DOI
  10.1002/bmc.1639
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590147, KAKENHI-PROJECT-22659213
[Journal Article] Alterations in extracellular tryptophan and dopamine concentrations in rat striatum following peripheral administration of D- and L-tryptophan: An in vivo microdialysis study2012
- Author(s)
  Yoshihara S, Otani H, Tsunoda M, Ishii K, Iizuka H, Ichiba H, Fukushima T
- Journal Title
  
  Neurosci lett
  
  Volume: 526 Issue: 1 Pages: 74-78
- DOI
  10.1016/j.neulet.2012.07.046
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590147
[Journal Article] Fluorimetric assay for D-amino acid oxidase activity in rat brain homogenate by using D-kynurenine as a substrate2012
- Author(s)
  Kozaki A, Iwasa S, Hosoda S, Nishiguchi Y, Nakayama M, Ichiba H, Fukushima T
- Journal Title
  
  BioScience Trends
  
  Volume: 6 Issue: 5 Pages: 241-247
- DOI
  10.5582/bst.2012.v6.5.241
- NAID
  130005054633
- ISSN
  1881-7815, 1881-7823
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590147
[Journal Article] Comparative study on kynurenic acid production in the rat striatum by tryptophan enantiomers: an in vivo microdialysis study2011
- Author(s)
  Ishii K, Iizuka H, Ogaya T, Song Z, Fukushima T
- Journal Title
  
  Chirality
  
  Volume: 23 Issue: 1E
- DOI
  10.1002/chir.20938
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590147
[Journal Article] Fluorescence determination of D- and L-tryptophan concentrations in rat plasma following administration of tryptophan enantiomers using HPLC with pre-column derivatization2011
- Author(s)
  Iizuka H, Ishii K, Hirasa Y, Kubo K, Fukushima T
- Journal Title
  
  J Chromatogr B
  
  Volume: 879 Issue: 29 Pages: 3208-3213
- DOI
  10.1016/j.jchromb.2011.02.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590147
[Journal Article] Enantiomeric separation of D, L-tryptophan and D, L-kynurenine by HPLC using pre-column fluorescence derivatization with R(-)-DBD-PyNCS2011
- Author(s)
  Iizuka H, Hirasa Y, Kubo K, Ishii K, Toyo'oka T, Fukushima T
- Journal Title
  
  Biomed Chromatogr
  
  Volume: 25 Issue: 7 Pages: 743-747
- DOI
  10.1002/bmc.1525
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590147
[Journal Article] Alteration in the plasma concentration of a DAAO inhibitor, 3-methylpyrazole-5-carboxylic acid, in the ketamine-treated rats and the influence on the pharmacokinetics of plasma D-tryptophan2011
- Author(s)
  Haruta N, Iizuka H, Ishii K, Yoshihara S, Ichiba H, Fukushima T
- Journal Title
  
  Proceedings of the Japan Academy, Series B
  
  Volume: 87 Issue: 10 Pages: 641-648
- DOI
  10.2183/pjab.87.641
- NAID
  130001471634
- ISSN
  0386-2208, 1349-2896
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590147
[Journal Article] Comparative study on kynurenic acid production in the rat striatum by tryptophan enantiomers : an in vivo microdialysis study2011
- Author(s)
  Ishii K, Iizuka H, Ogaya T, Song Z, Fukushima T
- Journal Title
  
  Chirality
  
  Volume: 23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590147
[Journal Article] Inhibition of D-amino acid oxidase activity by antipsychotic drugs evaluated by a fluorometric assay using D-kynurenine as substrate2011
- Author(s)
  Iwasa S, Tabara H, Song Z, Nakabayashi M, Yokoyama Y, Fukushima T
- Journal Title
  
  Yakugaku Zasshi
  
  Volume: 131 Pages: 1111-1116
- NAID
  130000927001
- URL
  https://www.jstage.jst.go.jp/article/yakushi/131/7/131_7_1111/_pdf
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590147
[Journal Article] Utilization of kynurenic acid produced from D-kynurenine in an in vitro assay of D-amino acid oxidase activity2010
- Author(s)
  Song Z, Ogaya T, Ishii K, Ichiba H, Iizuka H, Fukushima T
- Journal Title
  
  J Health Sci
  
  Volume: 56 Pages: 341-346
- NAID
  130000254735
- URL
  https://www.jstage.jst.go.jp/article/jhs/56/3/56_3_341/_pdf
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590147
[Journal Article] Changes in the plasma concentrations of D-kynurenine and kynurenic acid in rats after intraperitoneal administration of tryptophan enantiomers2010
- Author(s)
  Ishii K, Ogaya T, Song Z, Iizuka H, Fukushima T
- Journal Title
  
  Chirality
  
  Volume: 22 Issue: 10 Pages: 901-906
- DOI
  10.1002/chir.20850
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590147
[Journal Article] Changes in extracellular kynurenic acid concentrations in rat prefrontal cortex after D-kynurenine infusion: An in vivo microdialysis study2010
- Author(s)
  Ogaya T, Song Z, Ishii K, Fukushima T
- Journal Title
  
  Neurochem Res
  
  Volume: 35 Issue: 4 Pages: 559-563
- DOI
  10.1007/s11064-009-0099-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590147
[Journal Article] Fluorescence determination of N-acetylaspartic acid in the rat cerebrum homogenate by using high-performance liquid chromatorgraphy with pre-column fluorescence derivatization2008
- Author(s)
  Takeshi Fukushima
- Journal Title
  
  Biomed.Chromatogr 22
  
  Pages: 100-105
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590132
[Journal Article] Fluorescence determination ofN-acetylaspartic acid in the rat cerebrum homogenate by using high-performance liquid chromatography with pre-column fluorescence derivatization2008
- Author(s)
  Takeshi, Fukushima
- Journal Title
  
  Biomed. Chromatogr 22
  
  Pages: 100-105
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590132
[Journal Article] Fluorescence determination of N-acetylaspartic acid in the rat cerebrum homogenate using high-performance liquid chromatography with pre-column fluorescence derivatization.2008
- Author(s)
  Takeshi Fukushima
- Journal Title
  
  Biomedical Chromatography 22
  
  Pages: 100-105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590132
[Journal Article] Determination of rat brain kynurenic acid by column-switching HPLC with fluorescence detection2007
- Author(s)
  Takeshi, Fukushima
- Journal Title
  
  Biomed. Chromatogr 21
  
  Pages: 514-519
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590132
[Journal Article] Determination of kynurenic acid in human serum and its correlation with the concentration of certain amion acid2007
- Author(s)
  Takeshi Fukushima
- Journal Title
  
  Clin.Chim.Acta 377
  
  Pages: 174-178
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590132
[Journal Article] Determination of rat brain kynurenic acid by column-switching HPLC with fluorescence detection2007
- Author(s)
  Takeshi Fukushima
- Journal Title
  
  Biomed.Chromatogr 21
  
  Pages: 514-519
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590132
[Journal Article] Determination of kynurenic acid in human serum and its correlation with the concentration of certain amino acids2007
- Author(s)
  Takeshi, Fukushima
- Journal Title
  
  Clin. Chim. Acta 377
  
  Pages: 174-178
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590132
[Journal Article] Determination of Kynurenic acid in human serum and its correlation with the concentration of certain amino acids.2007
- Author(s)
  Takeshi Fukushima
- Journal Title
  
  Clin. Chim. Acta 377・1-2
  
  Pages: 174-178
- Data Source
  KAKENHI-PROJECT-17590132
[Journal Article] Determination of rat brain kynurenic acid by column-switching HPLC with fluorescence detection.2007
- Author(s)
  Takeshi Fukushima
- Journal Title
  
  Biomed Chromatogr. 21・5
  
  Pages: 514-519
- Data Source
  KAKENHI-PROJECT-17590132
[Journal Article] Determination of fluoxetine and norfluoxetine in rat brain microdialysis samples following intraperitoneal fluoxetine administration2004
- Author(s)
  Fukushima, Takeshi
- Journal Title
  
  Analytica Chimica Acta 522
  
  Pages: 99-104
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14572151
[Journal Article] Determination of fluoxetine and norfluoxetine in rat brain microdialysis samples following intraperitoneal fluoxetine administration2004
- Author(s)
  Takeshi Fukushima
- Journal Title
  
  Analytica Chimica Acta 522
  
  Pages: 99-104
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14572151
[Journal Article] Alteration of kynurenic acid concentration in rat plasma following optically pure kynurenine administration:A comparative study between enantiomers
- Author(s)
  Takeshi Fukushima
- Journal Title
  
  Chiraliry (印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590132
[Journal Article] Determination of L-tryptophan and L-kynurenine in human serum by using LC-MS after derivatization with (R)-DBD-PyNCS
- Author(s)
  Ohashi H, Iizuka H, Yoshihara S, Otani H, Kume M, Sadamoto K, Ichiba H, Fukushima T
- Journal Title
  
  Int J Trp Res
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590147
[Journal Article] Alteration of kynurenic acid concentration in rat plasma following optically pure kynurenine administration: A comparative study between enantiomers
- Author(s)
  Takeshi, Fukushima
- Journal Title
  
  Chirality (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590132
[Presentation] プレカラムキラル誘導体化試薬を用いた液体クロマトグラフィー-タンデム質量分析によるニンニク製品中のD-およびL-アミノ酸分析2023
- Author(s)
  小野里磨優，中野上晴菜，坂本達弥，海野真帆，福島健
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21K07399
[Presentation] LC-MS/MS用カルボン酸誘導体化試薬を用いた飲料中シトラマル酸の定量2023
- Author(s)
  小石海琴、海野真帆、小野里磨優、坂本達弥、福島健
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21K07399
[Presentation] キラルイミダゾリジノン環を有するLC-MS/MS用カルボン酸誘導体化試薬によるリンゴ中シトラマル酸の定量2023
- Author(s)
  海野真帆，坂本達弥，小野里磨優，小石海琴，福島健
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21K07399
[Presentation] キラルイミダゾリジノン環を有するLC-MS/MS用カルボン酸誘導体試薬によるヒト血清中有機酸の分析2023
- Author(s)
  海野真帆，坂本達弥，小野里磨優，福島健
- Organizer
  第67回日本薬学会関東支部大会（東京）
- Data Source
  KAKENHI-PROJECT-21K07399
[Presentation] キラルイミダゾリジノン環を有する LC-MS/MS 用カルボン酸誘導体化試薬による飲料中有機酸の分析2022
- Author(s)
  海野真帆、坂本達弥、小野里磨優、福島　健
- Organizer
  第66回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-21K07399
[Presentation] 初回エピソード精神病及び精神病発症危険状態におけるHcy-Met代謝の変動2020
- Author(s)
  小野里磨優、雅樂晏里沙、曲田彩夏、福岡尚実、一場秀章、辻野尚久、田形弘実、舩渡川智之、根本隆洋、水野雅文、福島健
- Organizer
  第140回日本薬学会年会
- Data Source
  KAKENHI-PROJECT-16K08944
[Presentation] Serum D- and L-lactate, pyruvate, and glucose levels in individuals with at-risk mental state and correlations with clinical symptoms.2019
- Author(s)
  Onozato M, Umino M, Shoji A, Ichiba H, Tsujino N, Funatogawa T, Tagata H, Nemoto T, Mizuno M, Fukushima T
- Organizer
  The 11th Joint Seminar on Biomedical Sciences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08944
[Presentation] 抗精神病薬未服薬の早期精神病における血清中グルタミン酸代謝物の解析2019
- Author(s)
  田形弘実, 辻野尚久, 小野里磨優, 舩渡川智之, 山口大樹, 片桐直之, 根本隆洋, 福島健, 水野雅文
- Organizer
  第29回日本臨床精神神経薬理学会
- Data Source
  KAKENHI-PROJECT-16K08944
[Presentation] Analyses of NMDA-receptor Co-agonists in Serum among Individuals with At-risk Mental State for Psychosis.2018
- Author(s)
  Hiromi Tagata, Naohisa Tsujino, Mayu Onozato, Naoyuki Katagiri, Taiju Yamaguchi, Takahiro Nemoto, Takeshi Fukushima, Masafumi Mizuno
- Organizer
  11th International Conference on Early Intervention in Mental Health (IEPA11)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08944
[Presentation] 精神病発症危険状態（ARMS）における血清中グルコース代謝物濃度の比較解析2018
- Author(s)
  小野里磨優, 辻野尚久,田形弘実, 海野真帆, 一場秀章, 舩渡川智之, 根本隆洋, 福島健, 水野雅文
- Organizer
  第15回東邦大学5学部合同学術集会
- Data Source
  KAKENHI-PROJECT-16K08944
[Presentation] 精神病発症危険状態（ARMS）における血清中代謝物濃度の比較解析2018
- Author(s)
  小野里磨優, 辻野尚久, 雅樂晏里沙, 岡西佑紀奈, 奥村郁実, 小沼利穂, 小畑香菜, 庄司礼子, 田形弘実, 舩渡川智之, 山口大樹, 片桐直之, 坂本達弥, 一場秀章, 根本隆洋, 水野雅文, 福島　健
- Organizer
  第14回東邦大学5学部合同学術集会
- Data Source
  KAKENHI-PROJECT-16K08944
[Presentation] 精神病発症危険状態（ARMS）における血清中代謝物濃度の比較解析2018
- Author(s)
  小野里磨優, 辻野尚久, 雅樂晏里沙, 岡西佑紀奈, 奥村郁実, 小沼利穂, 小畑香菜, 庄司礼子, 田形弘実, 舩渡川智之, 山口大樹, 片桐直之, 坂本達弥, 一場秀章, 根本隆洋, 水野雅文, 福島健
- Organizer
  第138回日本薬学会年会
- Data Source
  KAKENHI-PROJECT-16K08944
[Presentation] 精神病発症危険状態（ARMS）における血清中グルコース代謝物濃度の比較解析2018
- Author(s)
  海野真帆, 小野里磨優, 辻野尚久, 田形弘実, 一場秀章, 舩渡川智之, 根本隆洋, 福島健, 水野雅文
- Organizer
  第139回日本薬学会年会
- Data Source
  KAKENHI-PROJECT-16K08944
[Presentation] 精神病発症危険状態（ARMS）における血清中グルコース代謝物濃度の比較解析2018
- Author(s)
  小野里磨優、海野真帆、一場秀章、福島健、辻野尚久, 舩渡川智之, 田形弘実, 根本隆洋, 水野雅文
- Organizer
  第48回日本神経精神薬理学会
- Data Source
  KAKENHI-PROJECT-16K08944
[Presentation] 精神病発症危険状態（ARMS）における血清中代謝物濃度の比較解析2017
- Author(s)
  小野里磨優，小山田紘子，一場秀章，福島健，辻野尚久，舩渡川智之，田形弘実，根本隆洋，水野雅文
- Organizer
  第47回日本神経精神薬理学会
- Data Source
  KAKENHI-PROJECT-16K08944
[Presentation] ARMS 患者，健常人血清中 L-Trp 及びその代謝物の濃度比較解析2017
- Author(s)
  小山田紘子, 内藤瑛子, 高橋周平, 鈴木祥, 福本実理, 小野里磨優, 一場秀章, 福島健, 辻野尚久, 船渡川智之, 田形弘実, 根本隆洋, 水野雅文
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター（宮城県・仙台市）
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-16K08944
[Presentation] 精神病発症危険状態（ARMS）における血清中低分子濃度解析2017
- Author(s)
  辻野尚久，福島健，片桐直之，山口大樹，飯塚英昭，小野里磨優，一場秀章，根本隆洋，水野雅文
- Organizer
  第13回東邦大学4学部合同学術集会
- Place of Presentation
  東邦大学健康科学部棟（千葉県・船橋市）
- Year and Date
  2017-03-11
- Data Source
  KAKENHI-PROJECT-16K08944
[Presentation] Analyses of endogenous metabolites in serum from at-risk mental state subjects2017
- Author(s)
  Ayako Shoji, Mayu Onozato, Hiroko Oyamada, Hideaki Ichiba,Takeshi Fukushima, Naohisa Tsujino, Tomoyuki Funatogawa, Hiromi Tagata, Takahiro Nemoto, Masafumi Mizuno
- Organizer
  10th Joint Seminar on Biomedical Sciences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08944
[Presentation] 精神病発症危険状態（ARMS）における末梢血グルタミン酸代謝物の解析2017
- Author(s)
  田形弘実, 辻野尚久, 小野里磨優, 舩渡川智之, 山口大樹, 片桐直之, 根本隆洋, 福島健, 水野雅文
- Organizer
  第21回日本精神保健・予防学会学術集会
- Data Source
  KAKENHI-PROJECT-16K08944
[Presentation] D-セリンによるリスペリドン誘発ドパミン放出ならびに代謝への影響：ラット脳線条体マイクロダイアリシスによる検討2016
- Author(s)
  小野里磨優, ◯ 福本実理, 中澤宏実, 石丸勝之, 永嶋千紘, 飯塚英昭, 一場秀章, 福島健
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-25460224
[Presentation] S-Methyl-L-cysteine (SMLC)と D-セリン併用投与によるラット線条体 SMLC 及びD-セリンの変動解析2016
- Author(s)
  ◯ 小野里磨優, 石丸勝之, 永嶋千紘, 福本実理, 飯塚英昭, 一場秀章, 福島健
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-25460224
[Presentation] Biomarkers during the schizophrenia onset using quantitative analyses of serum metabolites at risk mental state.2016
- Author(s)
  Tsujino N, Fukushima T, Katagiri N, Yamaguchi T, Iizuka H, Onozato M, Ichiba H, Nemoto T, Mizuno M
- Organizer
  The 10th International Conference on Early Intervention in Mental Health (IEPA 10)
- Place of Presentation
  ミラノ（イタリア）
- Year and Date
  2016-10-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08944
[Presentation] 抗精神病薬リスペリドンと D-Ser の併用投与によるラット血漿中 D-Ser 濃度の変動解析2016
- Author(s)
  ◯ 中澤宏実, 小野里磨優, 秤屋瞳, 永嶋千紘, 飯塚英昭, 一場秀章, 福島健
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-25460224
[Presentation] S-Methyl-L-cysteine (SMLC)投与によるラット線条体SMLC 及び D-セリンの変動解析2016
- Author(s)
  ◯ 小野里磨優, 石丸勝之, 永嶋千紘, 福本実理, 飯塚英昭, 一場秀章, 福島健
- Organizer
  第12回東邦大学4学部合同学術集会
- Place of Presentation
  東邦大学医学部学生ラウンジ（東京都大田区）
- Year and Date
  2016-03-12
- Data Source
  KAKENHI-PROJECT-25460224
[Presentation] リスペリドンおよびD-セリン併用投与によるD-セリンおよび神経伝達物質の変動解析2015
- Author(s)
  永嶋千紘, 宍倉美穂, 石丸勝之, 秤屋　瞳, 小野里磨優, 飯塚英昭, 一場秀章, 福島　健
- Organizer
  日本薬学会第135年会
- Place of Presentation
  デザイン・クリエイティブセンター神戸1F （兵庫・神戸）
- Year and Date
  2015-03-26
- Data Source
  KAKENHI-PROJECT-25460224
[Presentation] HPLC-蛍光アッセイ法による中枢作用薬のD-アミノ酸オキシターゼ阻害作用の評価2015
- Author(s)
  岩崎　恵, 小野里磨優, 永嶋千紘, 柏熊快之, 飯塚英昭, 一場秀章, 福島　健
- Organizer
  日本薬学会第135年会
- Place of Presentation
  デザイン・クリエイティブセンター神戸1F （兵庫・神戸）
- Year and Date
  2015-03-26
- Data Source
  KAKENHI-PROJECT-25460224
[Presentation] S-Methyl-L-cysteine（SMLC）とD-セリン併用投与によるラット線条体SMLC 及びD-セリンの変動解析2015
- Author(s)
  ◯ 小野里磨優, 石丸勝之, 永嶋千紘, 福本実理, 飯塚英昭, 一場秀章, 福島健
- Organizer
  第59回日本薬学会関東支部大会
- Place of Presentation
  日本大学薬学部（千葉県船橋市）
- Year and Date
  2015-09-12
- Data Source
  KAKENHI-PROJECT-25460224
[Presentation] ケタミン連続投与ラット血漿中トリプトファン及びその代謝物濃度の変動解析2013
- Author(s)
  福島健
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2013-03-28
- Data Source
  KAKENHI-PROJECT-23617027
[Presentation] フローインジェクション分析法による抗酸化能簡易測定系の開発～トリプトファン代謝物の次亜塩素酸イオン消去能評価～2012
- Author(s)
  一場秀章, 花海克哉, 田中美沙, 矢ヶ崎渓子, 福島健
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道札幌市、北海道大学
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-22590147
[Presentation] Determination of tryptophan and kynurenic acid concentrations in rats after intraperitoneal administration of tryptophan enantiomers2012
- Author(s)
  Takeshi Fukushima
- Organizer
  13th International Society for Tryptophan Research (ISTRY 2012)
- Place of Presentation
  Sydney (Australia)
- Year and Date
  2012-11-09
- Data Source
  KAKENHI-PROJECT-22590147
[Presentation] 思春期における変異DISC1遺伝子と精神的ストレスの相互作用はセリン系システムを崩壊させる2012
- Author(s)
  Yurie Matsumoto, Minae Niwa, Akihiro Mouri, Ziyu Song, Akira Sawa, Takeshi Fukushima, Norio Ozaki, Toshitaka Nabeshima
- Organizer
  第7回統合失調症学会
- Place of Presentation
  愛知県名古屋市、愛知県産業労働センター
- Year and Date
  2012-03-17
- Data Source
  KAKENHI-PROJECT-22590147
[Presentation] Determination of tryptophan and kynurenic acid concentrations in rats after intraperitoneal administration of tryptophan enantiomers2012
- Author(s)
  Takeshi Fukushima
- Organizer
  13th International Society for Tryptophan Research (ISTRY 2012)
- Place of Presentation
  Sydney(Australia)
- Year and Date
  2012-11-09
- Data Source
  KAKENHI-PROJECT-23617027
[Presentation] Determination of N-acetylaspartic acid in the brain homogenate of Shati knockout mice by using an HPLC with fluorescence detection2012
- Author(s)
  Takeshi Fukushima, Ziyu Song, Dan Ge, Kazuya Toriumi, Hiroyuki Watanabe, Toshitaka Nabeshima
- Organizer
  第8回東邦大学4学部合同学術集会
- Place of Presentation
  東京都大田区東邦大学大森病院5号館臨床講堂
- Year and Date
  2012-03-24
- Data Source
  KAKENHI-PROJECT-22590147
[Presentation] Pubertal interaction of mutant DISC1 and psychological stress disrupts the serine system and contributes to the aetiopathology of psychiatric disorders2012
- Author(s)
  Yurie Matsumoto, Minae Niwa, Akihiro Mouri, Ziyu Song, Norio Ozaki, Akira Sawa, Takeshi Fukushima, Toshitaka Nabeshima
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都府京都市、国立京都国際会館
- Year and Date
  2012-03-15
- Data Source
  KAKENHI-PROJECT-22590147
[Presentation] Indoleamine 2,3-Dioxygenase (IDO)阻害剤の活性測定2012
- Author(s)
  李〓, 清水愛菜, 深谷昇平, 岩佐澄子, 福島健, 横山祐作
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道札幌市、北海道大学
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-22590147
[Presentation] Increased kynurenic acid concentration in rat plasma by repeated ketamine administration2012
- Author(s)
  Takeshi Fukushima
- Organizer
  13th International Society for Tryptophan Research (ISTRY 2012)
- Place of Presentation
  Sydney(Australia)
- Year and Date
  2012-11-09
- Data Source
  KAKENHI-PROJECT-23617027
[Presentation] ケタミン処置ラットにおけるDAAO阻害剤3-メチルピラゾール-5-カルボン酸の血漿中濃度変動およびその血漿中D-トリプトファン動態への影響2012
- Author(s)
  春田尚美, 飯塚英昭, 石井香那, 吉原峻介, 一場秀章, 福島健
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道札幌市、北海道大学
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-22590147
[Presentation] HPLC-蛍光定量法によるShati遺伝子欠損マウス脳組織中N-アセチルアスパラギン酸の変動解析2011
- Author(s)
  福島健, 宋梓瑜, 葛丹, 鳥海和也, 渡辺裕之, 鍋島俊隆
- Organizer
  BMAS 2011
- Place of Presentation
  鳥取県米子市、大山ロイヤルホテル
- Year and Date
  2011-09-01
- Data Source
  KAKENHI-PROJECT-22590147
[Presentation] キヌレン酸生成を活用するD-アミノ酸酸化酵素阻害物質の新規蛍光アッセイ法2011
- Author(s)
  岩佐澄子, 田原翔志, 宋梓瑜, 中林萌, 横山祐作, 福島健
- Organizer
  第7回D-アミノ酸研究会
- Place of Presentation
  東京都文京区、東京医科歯科大学
- Year and Date
  2011-09-09
- Data Source
  KAKENHI-PROJECT-22590147
[Presentation] R(-)-DBD-PyNCSを用いるプレカラム蛍光誘導体化によるトリプトファン光学異性体腹腔内投与におけるラット血漿中のDおよびL-トリプトファンのHPLCによる蛍光定量2011
- Author(s)
  ◯ 飯塚英昭, 平佐康, 久保賀寿美, 石井香那, 福島　健
- Organizer
  第55回日本薬学会関東支部大会
- Place of Presentation
  東邦大学習志野キャンパス（千葉県船橋市）
- Data Source
  KAKENHI-PROJECT-23617027
[Presentation] 新規薬物依存抑制因子shatiは微小管の安定化に関与する2011
- Author(s)
  鳥海和也, 近藤水生, 本荘龍輝, 武藤瑛里子, 古関竹直, 永井拓, 宋梓瑜, 宮本嘉明, 新田淳美, 山田清文, 福島健, 鍋島俊隆
- Organizer
  平成23年度アルコール・薬物依存関連学会合同学術集会
- Place of Presentation
  愛知県名古屋市、愛知県産業労働センター
- Data Source
  KAKENHI-PROJECT-22590147
[Presentation] Fluorescent assay for D-amino acid oxidase Inhibitor utilizing the production of kynurenic acid2011
- Author(s)
  岩佐澄子, 田原翔志, 中林萌, 宋梓瑜, 横山祐作, 福島健
- Organizer
  第55回日本薬学会関東支部大会
- Place of Presentation
  千葉県船橋市、東邦大学
- Year and Date
  2011-10-08
- Data Source
  KAKENHI-PROJECT-22590147
[Presentation] HPLCを用いる脳および血漿中トリプトファン代謝物の蛍光定量2011
- Author(s)
  福島健
- Organizer
  第11回関東支部談話会
- Place of Presentation
  東京都、ゆうぽうと7階(招待講演)
- Year and Date
  2011-03-18
- Data Source
  KAKENHI-PROJECT-22590147
[Presentation] Determination of neuroactive compounds by HPLC with fluorescence detection in pre-clinical and clinical researches (Keynote Lecture IV)2011
- Author(s)
  Fukushima T
- Organizer
  The 7th Joint Seminar on Biomedical Sciences
- Place of Presentation
  Thailand, Hat Yai, Prince of Songkla University(招待講演)
- Year and Date
  2011-10-14
- Data Source
  KAKENHI-PROJECT-22590147
[Presentation] 新規薬物依存抑制因子shatiの機能解析Functional analysis of a novel drug dependence-inhibitory factor "shati"2011
- Author(s)
  Kazuya Toriumi, Minae Niwa, Takenao Koseki, Taku Nagai, Ziyu Song, Yoshiaki Miyamoto, Atsumi Nitta, Kiyohumi Yamada, Takeshi Fukushima, Toshitaka Nabeshima
- Organizer
  第54回日本神経化学会大会
- Place of Presentation
  石川県加賀市、瑠璃光
- Year and Date
  2011-09-26
- Data Source
  KAKENHI-PROJECT-22590147
[Presentation] (R)-(-)-DBD-PyNCSを用いるプレカラム蛍光誘導体化法によるマウス脳内トリプトファンのHPLC-蛍光定量2011
- Author(s)
  飯塚英昭, ○渡邉祥子, 越川真祐子, 大橋隼人, 松本　友里恵, 青山雄紀, 鍋島俊隆, 福島健
- Organizer
  第33回日本トリプトファン研究会学術集会
- Place of Presentation
  東邦大学習志野キャンパス（千葉県船橋市）
- Data Source
  KAKENHI-PROJECT-23617027
[Presentation] HPLC-蛍光検出法によるマウス脳組織中N-アセチルアスパラギン酸の定量2011
- Author(s)
  福島健, ほか
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡県、グランシップ
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-22590147
[Presentation] Determination of neuroactive compounds by HPLC with fluorescence detection in pre-clinical and clinical researches (Keynote Lecture IV)2011
- Author(s)
  Takeshi Fukushima
- Organizer
  The 7th Joint Seminar on Biomedical Sciences
- Place of Presentation
  Hat Yai (Thailand)
- Data Source
  KAKENHI-PROJECT-22590147
[Presentation] shati遺伝子欠損マウスにおける行動異常と脳内の神経化学的な変化2011
- Author(s)
  本荘龍輝, 鳥海和也, 渡辺裕之, 宋梓瑜, 近藤水生, 武藤瑛里子, 間宮隆吉, 新田淳美, 福島健, 鍋島俊隆
- Organizer
  平成23年度アルコール・薬物依存関連学会合同学術集会
- Place of Presentation
  愛知県名古屋市、愛知県産業労働センター
- Data Source
  KAKENHI-PROJECT-22590147
[Presentation] (R)-(-)-DBD-PyNCSを用いるプレカラム蛍光誘導体化法によるマウス脳内トリプトファンのHPLC-蛍光定量2011
- Author(s)
  飯塚英昭, 渡邉祥子, 越川真祐子, 大橋隼人, 松本友里恵, 青山雄紀, 鍋島俊隆, 福島健
- Organizer
  第33回日本トリプトファン研究会学術集会
- Place of Presentation
  千葉県船橋市、東邦大学
- Year and Date
  2011-12-04
- Data Source
  KAKENHI-PROJECT-22590147
[Presentation] Effect of repeated ketamine treatment on the plasma concentration of a DAAO-inhibitory compound, 3-methylpyrazole-5-carboxylic acid, following its administration to rats2011
- Author(s)
  Haruta N, Iizuka H, Ishii K, Yoshihara S, Fukushima T
- Organizer
  The 7th Joint Seminar on Biomedical Sciences
- Place of Presentation
  Thailand, Hat Yai, Prince of Songkla University
- Year and Date
  2011-10-13
- Data Source
  KAKENHI-PROJECT-22590147
[Presentation] R(-)-DBD-PyNCSを用いるプレカラム蛍光誘導体化によるトリプトファン光学異性体腹腔内投与におけるラット血漿中のDおよびL-トリプトファンのHPLCによる蛍光定量2011
- Author(s)
  飯塚英昭, 平佐康, 久保賀寿美, 石井香那, 福島健
- Organizer
  第55回日本薬学会関東支部大会
- Place of Presentation
  千葉県船橋市、東邦大学
- Year and Date
  2011-10-08
- Data Source
  KAKENHI-PROJECT-22590147
[Presentation] フローインジェクション分析法による抗酸化能簡易評価系の開発～トリプトファン代謝物の次亜塩素酸イオン消去能評価～2011
- Author(s)
  一場秀章, 花海克哉, 田中美沙, 矢ヶ崎渓子, 福島健
- Organizer
  第33回日本トリプトファン研究会学術集会
- Place of Presentation
  千葉県船橋市、東邦大学
- Year and Date
  2011-12-04
- Data Source
  KAKENHI-PROJECT-22590147
[Presentation] HPLCを用いる脳および血漿中トリプトファン代謝物の蛍光定量2011
- Author(s)
  福島健
- Organizer
  第11回関東支部談話会
- Place of Presentation
  東京
- Year and Date
  2011-03-18
- Data Source
  KAKENHI-PROJECT-22590147
[Presentation] HPLCによる生体分子の蛍光定量法とその応用(教育講演)2010
- Author(s)
  福島健
- Organizer
  第14回神経科学領域における分子モニタリングシンポジウム
- Place of Presentation
  静岡
- Year and Date
  2010-06-04
- Data Source
  KAKENHI-PROJECT-22590147
[Presentation] HPLCによる生体分子の蛍光定量法とその応用(教育講演)2010
- Author(s)
  福島健
- Organizer
  第14回神経科学領域における分子モニタリングシンポジウム
- Place of Presentation
  静岡県、静岡県立大学(招待講演)
- Year and Date
  2010-06-04
- Data Source
  KAKENHI-PROJECT-22590147
[Presentation] D-アミノ酸酸化酵素によるD-キヌレニンからキヌレン酸への代謝生成とその応用2010
- Author(s)
  福島健, ほか
- Organizer
  第32回日本トリプトファン研究会
- Place of Presentation
  滋賀県、滋賀県立大学
- Year and Date
  2010-12-05
- Data Source
  KAKENHI-PROJECT-22590147
[Presentation] HPLCを用いる生体内D-セリンの分析研究2010
- Author(s)
  福島健
- Organizer
  第9回東邦大学薬学部オープンリサーチセンター公開セミナー
- Place of Presentation
  千葉県、東邦大学
- Year and Date
  2010-10-20
- Data Source
  KAKENHI-PROJECT-22590147
[Presentation] HPLC-蛍光検出による生体分子の定量とその応用研究～D-serine やNAAの定量法の話を中心に2010
- Author(s)
  福島健
- Organizer
  名城大学学術フロンティア推進事業特別講演会
- Place of Presentation
  名古屋
- Year and Date
  2010-12-03
- Data Source
  KAKENHI-PROJECT-22590147
[Presentation] HPLC-蛍光検出による生体分子の定量とその応用研究～D-serineやNAAの定量法の話を中心に2010
- Author(s)
  福島健
- Organizer
  名城大学学術フロンティア推進事業特別講演会
- Place of Presentation
  愛知県、名城大学薬学部(招待講演)
- Year and Date
  2010-12-03
- Data Source
  KAKENHI-PROJECT-22590147
[Presentation] Comparative study on the kynurenic acid production in rat between tryptophan enantiomers2010
- Author(s)
  Takeshi Fukushima
- Organizer
  22nd International Symposium on Chirality (ISCD 2010)
- Place of Presentation
  Sapporo
- Year and Date
  2010-07-14
- Data Source
  KAKENHI-PROJECT-22590147
[Presentation] D-アミノ酸酸化酵素によるD-キヌレニンからキヌレン酸への代謝生成とその応用2010
- Author(s)
  福島健
- Organizer
  第32回日本トリプトファン研究会
- Place of Presentation
  彦根
- Year and Date
  2010-12-05
- Data Source
  KAKENHI-PROJECT-22590147
[Presentation] Determination of fluoxetine enantiomers by pre-column fluorescence derivatization with NBD-COCl and column-switching HPLC2006
- Author(s)
  Takeshi, Fukushima
- Organizer
  Seventh Japan-China International Symposium on Health Sciences
- Place of Presentation
  Shizuoka
- Year and Date
  2006-11-05
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590132
[Presentation] Determination of fluoxeine enantiomers by pre-column fluorescence derivatization with NBD-COCl and column-switching HPLC2006
- Author(s)
  Takeshi Fukushima
- Organizer
  第7回日中健康科学シンポジウム
- Place of Presentation
  静岡
- Year and Date
  2006-11-05
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590132
[Presentation] Increased kynurenic acid concentration in rat plasma by repeated ketamine administration.
- Author(s)
  Takeshi Fukushima
- Organizer
  13th International Society for Tryptophan Research (ISTRY 2012)
- Place of Presentation
  SMC（Sydney）
- Data Source
  KAKENHI-PROJECT-22590147
[Presentation] ケタミン連続投与ラット血漿中トリプトファン及びその代謝物濃度の変動解析
- Author(s)
  福島健
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-22590147
[Presentation] Determination of tryptophan and kynurenic acid concentrations in rats after intraperitoneal administration of tryptophan enantiomers.
- Author(s)
  Takeshi Fukushima
- Organizer
  13th International Society for Tryptophan Research (ISTRY 2012)
- Place of Presentation
  SMC（Sydney）
- Data Source
  KAKENHI-PROJECT-22590147
[Presentation] 6年制薬学教育の中でのHPLC分析研究活動
- Author(s)
  福島健
- Organizer
  第9回千葉県分析化学交流会
- Place of Presentation
  東邦大学（千葉県）
- Invited
- Data Source
  KAKENHI-PROJECT-22590147
[Presentation] Determination of tryptophan and kynurenic acid concentrations in rats after intraperitoneal administration of tryptophan enantiomers.
- Author(s)
  Takeshi Fukushima
- Organizer
  13th International Society for Tryptophan Research
- Place of Presentation
  シドニー（オーストラリア）
- Data Source
  KAKENHI-PROJECT-23617027
[Presentation] 統合失調症治療薬のヒトDAO活性阻害作用の評価：in vitro実験による検討
- Author(s)
  宍倉美穂，柏熊快之，秤屋　瞳，岩佐澄子，一場　秀章，吉尾　隆，頼田和子，福井　清，福島　健
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本市民体育館（熊本県熊本市）
- Data Source
  KAKENHI-PROJECT-25460224
[Presentation] ヒトDAAO活性阻害評価のin vitro アッセイ法－統合失調症治療薬の阻害作用－
- Author(s)
  福島　健, 宍倉美穂, 岩佐澄子, 吉尾　隆, 一場秀章, 頼田和子, 福井　清
- Organizer
  第23回日本臨床精神神経薬理学会・第43回日本神経精神薬理学会合同年会
- Place of Presentation
  沖縄コンベンションセンター（沖縄県宜野湾市）
- Data Source
  KAKENHI-PROJECT-25460224
[Presentation] 統合失調症治療薬のヒトDAAO 活性阻害作用の評価: in vitro 実験による検討
- Author(s)
  宍倉美穂, 秤屋瞳, 岩佐澄子, 吉尾隆, 一場秀章, 頼田和子, 福井清, 福島健
- Organizer
  第26回バイオメディカル分析科学シンポジウム（BMAS 2013）
- Place of Presentation
  昭和大学薬学部（東京都品川区）
- Data Source
  KAKENHI-PROJECT-25460224

1. SANTA Tomofumi (30187306)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. NISHIGUCHI Yoshikazu (60459823)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. IMAI Kazuhiro (50012620)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. HOMMA Hiroshi (50190278)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 辻野尚久 (00459778)

# of Collaborated Projects: 2 results

# of Collaborated Products: 17 results
6. IIZUKA Hideaki (10057771)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
7. ICHIBA Hideaki (80120236)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. SADAMOTO Kiyomi (00297673)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. 田形弘実 (50888542)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. FUJIWAKE Hideshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. ONOZATO Mayu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Fukushima Takeshi 福島 健

福島 健 フクシマ タケシ

FUKUSHIMA Takeshi 福島 健

FUKUSHIMA Takashi 福島 健

Research Projects

Research Products

Co-Researchers

Metabolomics of biomolecules in serum from individuals with at-risk mental state and first-episode psychosis: discovery of reliable marker to develop psychosisPrincipal Investigator

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Analyses of metabolites in serum of individuals with ARMS and the development of the novel analytical method for diagnosis of ARMS.Principal Investigator

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Effect of antipsychotics on efficacy of D-serinePrincipal Investigator

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Clinical research on the central nervous system disorder by quantitative determination of serum tryptophan metabolites

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Investigation on the production and/or metabolism of D-kynurenine in schizophreniaPrincipal Investigator

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Researches on the in vivo analyses of brain neurotransmitters in the animal model of schizophreniaPrincipal Investigator

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蛍光偏光度測定による内分泌撹乱物質のスクリーニング法の開発

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in vivo analytical study on the endogenous agonist for cannabinoid receptor by using a microdialysis techniquePrincipal Investigator

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カラムスイッチングHPLCによるアナンダミドおよび類縁体の高感度定量法の開発Principal Investigator

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Development of high-performance amino acid sequensor of peptides

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光学活性薬物のHPLCによる高感度光学分割検出法に関する研究Principal Investigator

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Studies on the establishment of the analytical method for, and the distribution and change of the total D-amino acids in mammalian body

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[Journal Article] Determination of D- and L-Amino Acids in Garlic Foodstuffs by Liquid Chromatography-Tandem Mass Spectrometry2023

Fukushima Takeshi 福島健

福島健フクシマタケシ

FUKUSHIMA Takeshi 福島健

FUKUSHIMA Takashi 福島健