MORIYA Kyoji 森屋恭爾

Researcher Number	00272550
Affiliation (based on the past Project Information) *help	2009 – 2018: The University of Tokyo, 医学部附属病院, 教授 2008: The University of Tokyo, 医学部附属病院, 講師 2007 – 2008: 東京大学, 医学部・附属病院, 講師 2006: 東京大学, 医学部附属病院, 講師n 2002 – 2005: THE UNIVERSITY OF TOKYO, FACULTY OF MEDICINE, LECTURER, 医学部附属病院, 講師 … More 2003: 東京大学, 医学部・附属病院, 講師 2001 – 2002: 東京大学, 大学院・医学系研究科, 講師 2000 – 2001: TOKYO UNIV., DPT OF MEDICINE, ASSISTANT PROFESSOR, 医学部・附属病院, 講師 2000: 東京大学, 医学部・附属病院分院, 講師 Less
Review Section/Research Field	Principal Investigator Gastroenterology / Gastroenterology Except Principal Investigator Gastroenterology / Biological Sciences / Gastroenterology / Metabolomics / 内科学一般 / Ophthalmology
Keywords	Principal Investigator HCV / ROS / C型肝炎ウイルス / ミトコンドリア / nuclear receptor / Lipid metabolism / Insulin resistance / 核内レセプター / 脂質代謝 / インスリン抵抗性 … More / alcohol / hydroperoxide / transgenic mouse / Hepatitis C virus / 脂質 / アルコール / 過酸化脂質 / トランスジェニックマウス / 肝臓学 / C型肝炎 … More Except Principal Investigator トランスジェニックマウス / 肝癌 / C型肝炎 / コア蛋白 / transgenic mouse / core protein / transgenic mice / hepatitis C virus / 脂肪化 / 炎症 / 酸化ストレス / 肝発癌 / cytokine / mutation / tolerance / HBV-DNA / steatosis / 肝臓 / C型肝炎ウイルス / ミトコンドリア / 細胞内シグナル伝達 / 肝炎 / コア蛋白、 / トランスジェニックマウス、 / 眼薬理学 / 抗VEGF療法 / 血管周皮細胞 / VEGF / 代謝改善薬 / 糖尿病網膜症 / 脂肪肝 / NASH / 内科 / 肥満 / ウイルス / B型肝炎 / 核酸変異 / 抗原提示 / 免疫応答 / HBV / alcohol / cytotoxic lymphocytes / inflammation / hepatocarcinogeneis / アルコール / 細胞障害性リンパ球 / insulin resistance / retinoid X receptor / intracellular signal transduction / oxidative stress / hepatocarcinogenesis / アポリポ蛋白 / DNA障害 / β酸化 / AP-1 / MAPK / ROS / 肝細胞癌 / インスリン抵抗性 / レチノイドX受容体 / 肺発がん / caspase / protease / protein transduction / カスパーゼ / プロテアーゼ / プロテイン・トランスダクション / reactive oxygen species / hepatitis / hepatocellular carcinoma / 中性脂肪 / トランスジェニックマスス / 不飽和脂肪酸、 / 脂肪化、 / C型肝炎、 / 肝癌、 / RXRレセプター / 不飽和脂肪酸 / 遺伝子変異 / 肝炎ウイルス / 糖代謝 / コレステロール / 小胞体ストレス / spheroid HepG2細胞 / APoE rich Lipoprotein / ステロリン / 胆汁 / NPC1L1 / ABCG8 / ABCG5 / 脂質代謝 / レプリコン / 肝再生 / HIV・HCV重複感染症 / 肝線維化 / HIV感染症 / Cre-loxP / CRE-loxP / 機能解析 / HBx蛋白 / B型肝炎ウイルス / サイトカイン / バキュロウイルス / インターフェロンガンマ / サイトカイン、 / バキュロウイルス、 / 肝炎、 Less

Metabolic stimulant serves as a substitute for anti-VEGF injection therapy?
- Principal Investigator
  
  SHIRAYA TOMOYASU
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Ophthalmology
- Research Institution
  The University of Tokyo
Elucidation of synergy in hepatocarcinogenesis by hepatitis B virus, inflammation and hypernutrition
- Principal Investigator
  
  KOIKE KAZUHIKO
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo
Elucidation of spiral interactions of virus and inflammation in hepatitis C-associated hepatocarcinogenesis as revealed by microRNA analysis
- Principal Investigator
  
  KOIKE KAZUHIKO
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo
Modulation of endoplasmic reticulum stress by modification of cholesterol contents in liver.
- Principal Investigator
  
  TSUKAMOTO Kazuhisa
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Fukushima Medical University
C型肝炎ウイルスによる肝発癌機構の解明:細胞内標的の探索と治療法の開発
- Principal Investigator
  
  小池和彦
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Study of Mitochondria dysfunction mechanism caused by HCV infection.Principal Investigator
- Principal Investigator
  
  MORIYA Kyoji
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo
Analyses on the mechanisms for cholesterol excretion from liver.
- Principal Investigator
  
  TSUKAMOTO Kazuhisa
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo
C型肝炎ウイルスによる肝発癌機構の解明
- Principal Investigator
  
  小池和彦
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
HIV感染によるC型慢性肝炎進行促進機序の解明
- Principal Investigator
  
  小池和彦
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo
Regulation of hepatocarcinogenesis by using antagonists to retinoid X receptor alpha RXRalpha.Principal Investigator
- Principal Investigator
  
  MORIYA Kyoji
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo
強発癌性B型肝炎ウイルスの同定
- Principal Investigator
  
  小池和彦
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  内科学一般
- Research Institution
  The University of Tokyo
Study on the mechanism of hepatocarcinogenesis in hepatitis C viral infection
- Principal Investigator
  
  KOIKE Kazuhiko
- Project Period (FY)
  2001 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
THE ROLES OF HEPATITIS C VIRUS AND INFLAMMATION IN THE PATHOGENESIS OF HEPATOCELLULAR CARCINOMA
- Principal Investigator
  
  KOIKE Kazuhiko
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  THE UNIVERSITY OF TOKYO
The comparison of virus genome and immune reaction between asymptomatic carriers and chronic hepatitis patients infected with HBV.
- Principal Investigator
  
  MARUYAMA Toshiyuki
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo
DEVELOPMENT OF THERAPY FOR HEPATITIS C USING PROTEIN TRANSDUCTION METHOD
- Principal Investigator
  
  KOIKE Kazuhiko
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo
Studies on synergistic effects of the HBV and HCV in hepatocarcinogenesis by using transgenic mice modelPrincipal Investigator
- Principal Investigator
  
  MORITA Kyoji
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo
肝発癌制御ワクチンの開発
- Principal Investigator
  
  KOIKE KAZUHIKO
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  内科学一般
- Research Institution
  The University of Tokyo
THE MECHANISM OF STEATOSIS IN CHRONIC HEPATITIS : THE ROLE IN HEPATOCARCINOGENESIS.
- Principal Investigator
  
  KOIKE Kazuhiko
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Gastroenterology
- Research Institution
  UNIVERSITY OF TOKYO

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All Journal Article Presentation

[Journal Article] The intrahepatic expression levels of bile acid transporters are inversely correlated with the histological progression of nonalcoholic fatty liver disease2016
- Author(s)
  Okushin K, Tsutsumi T, Enooku K, Fujinaga H, Kado A, Shibahara J, Fukayama M, Moriya K, Yotsuyanagi H, Koike K
- Journal Title
  
  J Gastroenterol
  
  Volume: 51 Issue: 8 Pages: 808-818
- DOI
  10.1007/s00535-015-1148-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04807
[Journal Article] Mitochondrial iron accumulation exacerbates hepatic toxicity caused by hepatitis C virus core protein2015
- Author(s)
  Sekine S, Ito K, Watanabe H, Nakano T, Moriya K, Shintani Y, Fujie H, Tsutsumi T, Miyoshi H, Fujinaga H, Shinzawa S, Koike K, Horie T.
- Journal Title
  
  Toxicol Appl Pharmacol
  
  Volume: 282 Issue: 3 Pages: 237-243
- DOI
  10.1016/j.taap.2014.12.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390183, KAKENHI-PROJECT-26460190, KAKENHI-PROJECT-26670084
[Journal Article] Activation-induced cytidine deaminase is dispensable for virus-mediated liver and skin tumor development in mouse models.2014
- Author(s)
  Nguyen T, Xu J, Chikuma S, Hiai H, Kinoshita K, Moriya K, Koike K, Marcuzzi GP, Pfister H, Honjo T, Kobayashi M.
- Journal Title
  
  Int Immunol
  
  Volume: 26 Issue: 7 Pages: 397-406
- DOI
  10.1093/intimm/dxu040
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390183, KAKENHI-PROJECT-25440007, KAKENHI-PROJECT-25460363, KAKENHI-PROJECT-22000015
[Journal Article] High ubiquitous mitochondrial creatine kinase expression in hepatocellular carcinoma denotes a poor prognosis with highly malignant potential.2013
- Author(s)
  Uranbileg B, Enooku K, Soroida Y, Ohkawa R, Kudo Y, Nakagawa H, Tateishi R, Yoshida H, Shinzawa S, Moriya K, Ohtomo N, Nishikawa T, Inoue Y, Tomiya T, Kojima S, Matsuura T, Koike K, Yatomi Y, Ikeda H.
- Journal Title
  
  Int J Cancer.
  
  Volume: 134 Issue: 9 Pages: 2189-98
- DOI
  10.1002/ijc.28547
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590961, KAKENHI-PROJECT-24390183, KAKENHI-PROJECT-25460981
[Journal Article] Effect of treatment with polynsatured fatty acids on Hcv-ordiet-induced fatty liver.2011
- Author(s)
  Koike K, Miyoshi H, Yotsuyanagi H, Moriya K.
- Journal Title
  
  J Hepatol.
  
  Volume: 4 Pages: 704-706
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590764
[Journal Article] LXR agonist increases apoE secretion from HepG2 spheroid, together with an increased production of VLDL and apoE-rich large HDL2011
- Author(s)
  Kurano M. Iso-O N. Hara M. Ishizaka N. Moriya K. Koike K. Tsukamoto K.
- Journal Title
  
  Lipids in Health and Disease
  
  Volume: 10 Pages: 134-134
- Data Source
  KAKENHI-PROJECT-23591333
[Journal Article] LXR agonist increases apoE secretion from HepG2 spheroid, together with an increased production of VLDL and apoE-rich large HDL.2011
- Author(s)
  Kurano M. Iso-O N. Hara M. Ishizaka N. Moriya K. Koike K. Tsukamoto K.
- Journal Title
  
  Lipids in Health and Disease
  
  Volume: 10 Pages: 134-134
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591333
[Journal Article] Pathogenesis of lipid metabolism disorder in hepatitis C : polyunsaturated fatty acids counteract lipid alterations induced by the core protein.2011
- Author(s)
  Miyoshi H, Moriya K, Tsutsumi T, Shinzawa S, Fujie H, Shintani Y, Fujinaga H, Goto K, Todoroki T, Suzuki T, Miyamura T, Matsuura Y, Yotsuyanagi H, Koike K.
- Journal Title
  
  J Hepatol. 54(3)
  
  Pages: 432-8
- Data Source
  KAKENHI-PROJECT-20590764
[Journal Article] Evaluation of multiplex PCR using dual-priming oligonucleotide for the detection of vanA and vanB in vancomycin-resistant enterococci.2011
- Author(s)
  Nagai R, Saito R, Koyano S, Okamura N, Yokota H, Kitazawa T, Moriya K.
- Journal Title
  
  Clin Chem Lab Med. 49(4)
  
  Pages: 751-2
- Data Source
  KAKENHI-PROJECT-20590764
[Journal Article] Liquid chromatographic separation of proteins derivatized with a fluorogenic reagent at cysteinyl residues on a non-porous column for differential proteomics analysis.2011
- Author(s)
  Koshiyama A, Ichibangase T, Moriya K, Koike K, Yazawa I, Imai K.
- Journal Title
  
  J Chromatogr A. 1218(22)
  
  Pages: 3447-52
- Data Source
  KAKENHI-PROJECT-20590764
[Journal Article] Reply to the Letter to the Editor 'Effect of treatment with polyunsatured fatty acids on HCV-or diet-induced fatty liver.2011
- Author(s)
  Koike K, Miyoshi H, Yotsuyanagi H, Moriya K.
- Journal Title
  
  J Hepatol. 54(6)
  
  Pages: 1326-1326
- Data Source
  KAKENHI-PROJECT-20590764
[Journal Article] Hepatitis C virus core protein compromises iron-induced activation of antioxidants in mice and HepG2 cells.2010
- Author(s)
  Moriya K, Miyoshi H, Shinzawa S, Tsutsumi T, Fujie H, Goto K, Shintani Y, Yotsuyanagi H, Koike K.
- Journal Title
  
  J Med Virol. 82(5)
  
  Pages: 776-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590764
[Journal Article] Lipid metabolism and liver disease in hepatitis C viral infection.2010
- Author(s)
  Koike K, Tsutsumi T, Yotsuyanagi H, Moriya K.
- Journal Title
  
  Oncology.
  
  Volume: 78suppll Pages: 24-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590764
[Journal Article] Lipid metabolism and liver disease in hepatitis C viral infection.2010
- Author(s)
  Koike K, Tsutsumi T, Yotsuyanagi H, Moriya K.
- Journal Title
  
  Oncology. 1
  
  Pages: 24-30
- Data Source
  KAKENHI-PROJECT-20590764
[Journal Article] Evaluation of a chromogenic agar medium for the detection of extended-spectrum ss-lactamase-producing Enterobacteriaceae.2010
- Author(s)
  Saito R, Koyano S, Nagai R, Okamura N, Moriya K, Koike
- Journal Title
  
  Left Appl Microbiol
  
  Volume: 51(6) Pages: 704-706
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590764
[Journal Article] Animal models for hepatitis C and related liver disease.2010
- Author(s)
  Koike K, Moriya K, Matsuura Y.
- Journal Title
  
  Hepatol Res. 40(1)
  
  Pages: 69-82
- NAID
  10027406832
- Data Source
  KAKENHI-PROJECT-20590764
[Journal Article] Hepatitis C virus core protein compromises iron-induced activation of antioxidants in mice and HepG2 cells.2010
- Author(s)
  Moriya K, Miyoshi H, Shinzawa S, Tsutsumi T, Fujie H, Goto K, Shintani Y, Yotsuyanagi H, Koike K.
- Journal Title
  
  J Med Virol.
  
  Volume: 82(5) Pages: 776-792
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590764
[Journal Article] Pathogenesis of lipid metabolism disorder in hepatitis C : polyunsaturated fatty acids counteract lipid alterations induced by the core protein.2010
- Author(s)
  Miyoshi H, Moriya K, Tsutsumi T, Shinzawa S, Fujie H, Shintani Y, Fujinaga H, Goto K, Todoroki T, Suzuki T, Miyamura T, Matsuura Y, Yotsuyanagi H, Koike K.
- Journal Title
  
  J Hepatol.
  
  Volume: 54(3) Pages: 432-438
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590764
[Journal Article] Tacrolimus ameliorates metabolic disturbance and oxidative stress caused by hepatitis C virus core protein: analysis using mouse model and cultured cells.2009
- Author(s)
  Moriya K, Miyoshi H, Tsutsumi T, Shinzawa S, Fujie H, Shintani Y, Yotsuyanagi H, Moriishi K, Matsuura Y, Suzuki T, Miyamura T, Koike K.
- Journal Title
  
  Am J Pathol. 175(4)
  
  Pages: 1515-24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590764
[Journal Article] Limitation of immunoaffinity column for the removal of abundant proteins from plasma in quantitative plasma proteomics.2009
- Author(s)
  Ichibangase T, Moriya K, Koike K, Imai K.
- Journal Title
  
  Biomed Chromatogr 23(5)
  
  Pages: 480-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590764
[Journal Article] Chronic hepatitis C in patients co-infected with human immunodeficiency virus in Japan : a retrospective multicenter analysis.2009
- Author(s)
  Yotsuyanagi H, Kikuchi Y, Tsukada K, Nishida K, Kato M, Sakai H, Takamatsu J, Hige S, Chayama K, Moriya K, Koike K.
- Journal Title
  
  Hepatol Res 39(7)
  
  Pages: 657-63
- NAID
  10025326580
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590764
[Journal Article] Analysis of plasmid-mediated multidrug resistance in Escherichia coli and Klebsiella oxytoca isolates from clinical specimens in Japan.2009
- Author(s)
  Ode T, Saito R, Kumita W, Sato K, Okugawa S, Moriya K, Koike K, Okamura N.
- Journal Title
  
  Int J Antimicrob Agents 34(4)
  
  Pages: 347-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590764
[Journal Article] Analysis of plasmid-mediated multidrug resistance in Escherichia coli and Klebsiella oxytoca isolates from clinical specimens in Japan.2009
- Author(s)
  Ode T, Saito R, Kumita W, Sato K, Okugawa S, Moriya K, Koike K, Okamura N.
- Journal Title
  
  Int J Antimicrob Agents. 34(4)
  
  Pages: 347-50
- Data Source
  KAKENHI-PROJECT-20590764
[Journal Article] Tacrolimus ameliorates metabolic disturbance and oxidative stress caused by hepatitis C virus core protein : analysis using mouse model and cultured cells.2009
- Author(s)
  Moriya K, Miyoshi H, Tsutsumi T, Shinzawa S, Fujie H, Shintani Y, Yotsuyanagi H, Moriishi K, Matsuura Y, Suzuki T, Miyamura T, Koike K.
- Journal Title
  
  Am J Pathol. 175(4)
  
  Pages: 1515-24
- Data Source
  KAKENHI-PROJECT-20590764
[Journal Article] Acquisition of methicillin-resistant Staphylococcus aureus after living donor liver transplantation: a retro spective cohort study.2009
- Author(s)
  Hashimoto M, Sugawara Y,Tamura S, Kaneko J,Matsui Y, Togashi J, Moriya K, Koike K, Makuuchi
- Journal Title
  
  BMC Infect Dis Nov11;8
  
  Pages: 155-161
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590764
[Journal Article] Tacrolimus ameliorates metabolic disturbance and oxidative stress caused by hepatitis C viruscore protein : Analysis using mouse model and cultured cells2009
- Author(s)
  Moriya K, Miyoshi H,…, Koike K.
- Journal Title
  
  Am J Pathol 175
  
  Pages: 1515-1524
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20012013
[Journal Article] Proteomics analysis of mitochondrial proteins reveals overexpression of a mitochondrial protein chaperon, prohibitin, in cells expressing hepatitis C virus core protein.2009
- Author(s)
  Tsutsumi T, Matsuda M, Aizaki H, Moriya K, Miyoshi H, Fujie H, Shintani Y, Yotsuyanagi H, Miyamura T, Suzuki T, Koike K.
- Journal Title
  
  Hepatology 50(2)
  
  Pages: 378-86
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590764
[Journal Article] Limitation of immunoaffinity column for the removal of Abundant proteins from plasma in quantitative plasma proteomics.2009
- Author(s)
  Ichibangase T, Moriya K, Koike K, Imai K.
- Journal Title
  
  Biomed Chromatogr May;23(5)
  
  Pages: 480-487
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590764
[Journal Article] Molecular characterizations of carbapenem and ciprofloxacin resistance in clinical isolates of Pseudomonas putida.2009
- Author(s)
  Kumita W, Saito R, Sato K, Ode T, Moriya K, Koike K, Chida T, Okamura N.
- Journal Title
  
  J Infect Chemother. 15(1)
  
  Pages: 6-12
- NAID
  10025128068
- Data Source
  KAKENHI-PROJECT-20590764
[Journal Article] Moleculer characterizations of carbapenem and ciprofloxacin resistance in clinical isolates of Pseudomonas putida2009
- Author(s)
  Kumita W, Saito R, Sato K, Ode T, Moriya K, Koike K, Chida T, Okamura N
- Journal Title
  
  Infect Chemother Feb:15(1)
  
  Pages: 6-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590764
[Journal Article] Metabolic aspects of hepatitis C : steatohepatitis distinct from NASH2005
- Author(s)
  Koike K, Moriya K.
- Journal Title
  
  J Gastroenterol 40
  
  Pages: 329-336
- Data Source
  KAKENHI-PROJECT-17659210
[Journal Article] Hepatitis C Virus Core Protein Exerts an Inhibitory Effect on Suppressor of Cytokine Signaling (SOCS)-1 Gene Expression.2005
- Author(s)
  Miyoshi H, Fujie H, Shintani Y, Tsutsumi T, Shinzawa S, Makuuchi M, Kokudo N, Matsuura Y, Suzuki T, Miyamura T, Moriya K, Koike K.
- Journal Title
  
  J Hepatol (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13214018
[Journal Article] Hepatitis C virus infection and diabetes : direct involvement of the virus in the develonment of insulin resistance2004
- Author(s)
  Shintani Y, Fujie H, Miyoshi H, Tsutsumi T, Tsukamoto K, Kimura S, Moriya K, Koike K.
- Journal Title
  
  Gastroenterology 126(3)
  
  Pages: 840-848
- Data Source
  KAKENHI-PROJECT-15590624
[Journal Article] Prevalence of measles, rubella, mumps, and varicella antibodies among healthcare workers in Japan2004
- Author(s)
  Hatakeyama S, Moriya K, Itoyama S, Nukui Y, Uchida M, Shintani Y, Morisawa Y, Kimura S.
- Journal Title
  
  Infection Control and Hospital Epidemiology 25(7)
  
  Pages: 591-594
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590624
[Journal Article] Methylation status of suppressor of cytokine sigasling-1 gene in hepatocellular carcinoma2004
- Author(s)
  Miyoshi H, Fujie H, Moriya K, Shintani Y, Tsutsumi T, Makuuchi M, Kimura S, Koike K.
- Journal Title
  
  J Gastroenterol 39(6)
  
  Pages: 563-569
- Data Source
  KAKENHI-PROJECT-15590624
[Journal Article] Methylation status of suppressor of cytokine signaling-1 gene in hepatocellular carcinoma.2004
- Author(s)
  Miyoshi H, Fujie H, Moriya K, Shintani Y, Tsutsumi T, Makuuchi M, Kimura S, Koike K.
- Journal Title
  
  Journal of Gastroenterology 39(6)
  
  Pages: 563-569
- NAID
  10013296326
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590624
[Journal Article] Prevalence of measles, rubella, mumps, and varicella antibodies among healthcare workers in Japan2004
- Author(s)
  Hatakeyama S, Moriya K, Itoyama S, Nukui Y, Uchida M, Shintani Y, Morisawa Y, Kimura S.
- Journal Title
  
  Infect Control Hosp Epidemiol 25(7)
  
  Pages: 591-594
- Data Source
  KAKENHI-PROJECT-15590624
[Journal Article] Hepatitis C virus infection and diabetes : direct involvement of the virus in the development of insulin resistance.2004
- Author(s)
  Shintani Y, Fujie H, Miyoshi H, Tsutsumi T, Tsukamoto K, Kimura S, Moriya K, Koike K.
- Journal Title
  
  Gastraenterolagy. 126(3)
  
  Pages: 840-848
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590624
[Journal Article] Hepatitis C virus and diabetes : direct involvement of the virus in the development of insulin resistance.2004
- Author(s)
  Shintani Y, Fujie H, Miyoshi H, Tsutsumi T, Kimura S, Moriya K, Koike K.
- Journal Title
  
  Gastroenterology 126
  
  Pages: 840-848
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13214018
[Journal Article] Prevalence of measles, rubella, mumps, and varicella antibodies among healthcare workers in Japan. International meeting2004
- Author(s)
  Hatakeyama S, Moriya K, Itoyama S, Nukui Y, Uchida M, Shintani Y, Morisawa Y, Kimura S
- Journal Title
  
  Infect Control Hosp Epidemiol. 25(7)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590624
[Journal Article] Hepatitis C virus infection and diabetes : direct involvement of the virus in the development of insulin resistance.2004
- Author(s)
  Shintani Y, Fujie H, Miyoshi H, Tsutsumi T, Tsukamoto K, Kimura S, Moriya K, Koike K.
- Journal Title
  
  Gastroenterology 126(3)
  
  Pages: 840-848
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590624
[Journal Article] Methylation status of suppressor of cytokine signaling-1 gene in hepatocellular carcinoma.2004
- Author(s)
  Miyoshi H, Fujie H, Moriya K, Shintani Y, Tsutsumi T, Makuuchi M, Kimura S, Koike K.
- Journal Title
  
  J Gastroenterol. 39(6)
  
  Pages: 563-569
- NAID
  10013296326
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590624
[Journal Article] Suzuki R, Miyamura T, Matsuura Y. Proteasome activator PA28g-dependent nuclear retention and degradation of hepatitis C virus core protein.2003
- Author(s)
  Moriishi K, Okabayashi T, Nakai K, Moriya K, Koike K, Murata K, Chiba T, Tanaka K
- Journal Title
  
  J Virol 77
  
  Pages: 10237-10249
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13214018
[Journal Article] Serum lipid profile of patients with genotype 1b hepatitis C viral infection in Japan.2003
- Author(s)
  Moriya K, Shintani Y, Fujie H, Miyoshi H, Tsutsumi T, Yotsuyanagi H, Iino S, Kimura S, Koike K.
- Journal Title
  
  Hepatol Res. 25(4)
  
  Pages: 371-376
- NAID
  50000829733
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590624
[Journal Article] Proteasome activator PA28gamma-dependent nuclear retention and degradation of hepatitis C virus core protein.2003
- Author(s)
  Moriishi K, Okabayashi T, Nakai K, Moriya K, Koike K, Murata S, Chiba T, Tanaka K, Suzuki R, Suzuki T, Miyamura T, Matsuura Y.
- Journal Title
  
  Journal of Virology 77(19)
  
  Pages: 10237-10249
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590624
[Journal Article] Hepatitis C virus core protein activates ERK and p38 MAPK in cooperation with ethanol in transgenic mice.2003
- Author(s)
  Tsutsumi T, Suzuki T, Moriya K, Shintani Y, Fujie H, Miyoshi H, Matsuura Y, Koike K, Miyamura T.
- Journal Title
  
  Hepatology 38(4)
  
  Pages: 820-828
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590624
[Journal Article] Proteasome activator PA28gamma-dependent nuclear retention and degradation of hepatitis C virus core protein.2003
- Author(s)
  Moriishi K, Okabayashi T, Nakai K, Moriya K, Koike K, Murata S, Chiba T, Tanaka K, Suzuki R, Suzuki T, Miyamura T, Matsuura Y.
- Journal Title
  
  J Virol. 77(19)
  
  Pages: 10237-10249
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590624
[Journal Article] Serum lipid profile of patients with genotype 1b hepatitis C viral infection in Japan2003
- Author(s)
  Moriya K, Shintani Y, Fujie H, Miyoshi H, Tsutsumi T, Yotsuyanagi H, Iino S, Kimura S, Koike K.
- Journal Title
  
  Hepatology Research 25(4)
  
  Pages: 371-376
- NAID
  50000829733
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590624
[Journal Article] Hepatitis C virus core protein activates ERK and p38 MAPK in cooperation with ethanol in transgenic mice.2003
- Author(s)
  Tsutsumi T, Suzuki T, Moriya K, Shintani Y, Fujie H, Miyoshi H, Matsuura Y, Koike K, Miyamura T.
- Journal Title
  
  Hepatology. 88(4)
  
  Pages: 820-828
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590624
[Journal Article] Miyamura T. Hepatitis C virus core protein activates ERK and p38 MAPK in cooperation with ethanol in transgenic mice.2002
- Author(s)
  Tsutsumi T, Suzuki T, Moriya K, Shintani Y, Fujie H, Miyoshi H, Matsuura Y, Koike K
- Journal Title
  
  Hepatology 38
  
  Pages: 820-828
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13214018
[Journal Article] Miyamura T. Interaction of Hepatitis C Virus Core Protein with Retinoid X Receptor-a Modulates its Transcriptional Activity.2002
- Author(s)
  Tsutsumi T, Suzuki T, Shimoike T, Moriya K, Yotsuyanagi H, Matsuura Y, Koike K
- Journal Title
  
  Hepatology 35
  
  Pages: 937-946
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13214018
[Journal Article] Miyamura T. Intrahepatic cytokine expression and AP-1 activation in mice transgenic for hepatitis C virus core protein.2002
- Author(s)
  Tsutsumi T, Suzuki T, Moriya K, Yotsuyanagi H, Shintani Y, Fujie H, Matsuura Y, Kimura S, Koike K
- Journal Title
  
  Virology 304
  
  Pages: 415-424
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13214018
[Journal Article] Increase in the concentration of carbon 18 monounsaturated fatty acids in the liver with hepatitis C : analysis in transgenic mice and humans.2001
- Author(s)
  Moriya K, Todoroki T, Tsutsumi T, Fujie H, Shintani Y, Miyoshi H, Ishibashi K, Takayama T, Makuuchi M, Watanabe K, Miyamura T, Kimura S, Koike K.
- Journal Title
  
  Biophys Biochem Res Commun 281
  
  Pages: 1207-1212
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13214018
[Journal Article] Oxidative stress in the absence of inflammation in a mouse model for hepatitis C virus-associated hepatocellular carcinogenesis.2001
- Author(s)
  Moriya K, Nakagawa K, Santa T, Shintani Y, Fujie H, Miyoshi H, Tsutsumi T, Miyazawa T, Ishibashi K, Horie T, Imai K, Miyamura T, Kimura S, Koike K.
- Journal Title
  
  Cancer Res 61
  
  Pages: 4365-4370
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13214018
[Journal Article] Oxidative stress in the absence of inflammation in a mouse model for hepatitis C virus-associated hepatocellular carcinogenesis.2001
- Author(s)
  Moriya K, et al.
- Journal Title
  
  Cancer Res 61
  
  Pages: 4365-4370
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13214018
[Journal Article] Frequent β-catenin aberration in human hepatocellular carcinoma.2001
- Author(s)
  Fujie H, Moriya K, Shintani Y, Tsutsumi T, Takayama T, Makuuchi M, Kimura S, Koike K.
- Journal Title
  
  Hepatol Res 20
  
  Pages: 39-51
- NAID
  10009899927
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13214018
[Journal Article] Virological analysis of non-B, non-C hepatocellular carcinoma in Japan : frequent involvement of hepatitis B virus2000
- Author(s)
  Yotsuyanagi H, Shintani Y, Moriya K, Fujie H, Tsutsumi T, Kato T, Nishioka K, Takayama T, Makuuchi M, Iino S, Kimura S, Koike K.
- Journal Title
  
  J Infect Dis 181
  
  Pages: 1920-1928
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13214018
[Journal Article] Hepatitis C virus core protein compromises iron-induced activation of antioxidants in mice and HepG2 cells.
- Author(s)
  Moriya K, Miyoshi H, Shinzawa S, Tsutsumi T, Fujie H, Goto K, Shintani Y, Yotsuyanagi H, Koike K.
- Data Source
  KAKENHI-PROJECT-20590764
[Presentation] HCV and hepatic steatosis2010
- Author(s)
  Kyoji Moriya
- Organizer
  The JSH single topic conference. Tokyo Japan. 2010
- Place of Presentation
  Tokyo. Japan
- Year and Date
  2010-11-18
- Data Source
  KAKENHI-PROJECT-20590764
[Presentation] Clinical characteristics and prognostic factors in patients with Stenotrophomonas maltophilia bacteremia.2010
- Author(s)
  Yoko Nukui Shuji Hatakeyama Kyoji Moriya, et al
- Organizer
  14th International Congress on Infection Diseases
- Place of Presentation
  U.S.A Miami
- Year and Date
  2010-03-09
- Data Source
  KAKENHI-PROJECT-20590764
[Presentation] HCV and hepatic steatosis The JSH single topic conference2010
- Author(s)
  Kyoji Moriya
- Organizer
  NASH2010
- Place of Presentation
  Tokyo Japan
- Year and Date
  2010-11-08
- Data Source
  KAKENHI-PROJECT-20590764
[Presentation] Decrease in patients acquiring metallo-bata-lactamase-producing Bacteria after introducing mandatory report system of carbapenem use,2009
- Author(s)
  Takatoshi Kitazawa, Yoko Nukui, Yoshizumi Shintani, Kyoji Moriya
- Organizer
  East Asian Conference on infection control and prevention
- Place of Presentation
  東京
- Year and Date
  2009-11-12
- Data Source
  KAKENHI-PROJECT-20590764
[Presentation] C型慢性肝炎における宿主因子と病態/治療2009
- Author(s)
  四柳宏, 森屋恭爾, 山田典栄, 岡本賢, 小林稔, 松永光太郎, 高橋秀明, 後藤耕司, 三好秀征, 堤武也, 藤江肇, 新谷良澄, 奥瀬千晃, 安田清美, 鈴木通博, 小池和彦
- Organizer
  日本肝臓学会大会
- Place of Presentation
  京都
- Year and Date
  2009-10-14
- Data Source
  KAKENHI-PROJECT-20590764
[Presentation] FK506 ameliorates metabolic disturbance and oxidative stress in hepatitis C virus infection2007
- Author(s)
  Moriya K, et. al.
- Organizer
  42nd Annual Meeting of the EUROPEAN ASSOCIATION FOR THE STUDY OF THE LIVER
- Place of Presentation
  スペイン(バルセロナ)
- Year and Date
  2007-04-24
- Data Source
  KAKENHI-PROJECT-18012014
[Presentation] Fluvastatin Ameliorates Liver Desease in HCV Mouse Model with Improvements of Lipid Metabolism, Mitochondrial Dysfunction and Intrahepatic Cardiolipin Composition.
- Author(s)
  Hidetaka Fujinaga ,Seiko Shinzawa,Junken Aoki,Kazuya Okushin,Kohji Goto,Hideyuki Miyoshi,Takeya Tsutsumi,Yoshizumi Shintani,Hiroshi Yotsuyanagi,Kyoji Moriya,Kazuhiko Koike
- Organizer
  48th Annual Meeting of the European Association for the Study of the Liver
- Place of Presentation
  Amsterdam RAI
- Data Source
  KAKENHI-PROJECT-24390183

1. KOIKE KAZUHIKO (80240703)

# of Collaborated Projects: 15 results

# of Collaborated Products: 28 results
2. SHINTANI Yoshizumi (80261965)

# of Collaborated Projects: 8 results

# of Collaborated Products: 21 results
3. FUJIE Hajime (90332577)

# of Collaborated Projects: 7 results

# of Collaborated Products: 10 results
4. 三好秀征 (00401042)

# of Collaborated Projects: 3 results

# of Collaborated Products: 15 results
5. 堤武也 (00726739)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
6. TSUKAMOTO Kazuhisa (20251233)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
7. 四柳宏 (30251234)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. ISOーO Naoyuki (80420214)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. WATANABE Tsuyoshi (80158641)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SATOH Hiroaki (20323595)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. KURANO Makoto (60621745)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. MARUYAMA Toshiyuki (30219571)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. MITSUI Hiroshi (30239280)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. SHIRAYA TOMOYASU (60572394)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 加藤聡 (20214372)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 荒木章之 (20724652)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 上田高志 (90631573)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. ISHOBASHI Kotaro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. MATSUURAI Yoshiharu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 富谷智明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 池田均

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MORIYA Kyoji 森屋 恭爾

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Study of Mitochondria dysfunction mechanism caused by HCV infection.Principal Investigator

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Regulation of hepatocarcinogenesis by using antagonists to retinoid X receptor alpha RXRalpha.Principal Investigator

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MORIYA Kyoji 森屋恭爾