Hotta Tetsuo 堀田哲夫

… Alternative Names

堀田哲夫ホツタテツオ

HOTTA Tetsuo 堀田哲夫

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Researcher Number	00272815
Affiliation (based on the past Project Information) *help	2015 – 2017: 新潟大学, 医歯学総合病院, 准教授 2013: 新潟大学, 医歯学総合病院, 准教授 2003: NIIGATA UNIVERSITY, Medical and Dental Hospital, Associate Professor, 医歯学総合病院, 助教授 2002: 新潟大学, 医学部附属病院, 助教授 2001: NIIGATA UNIVERSITY, Medical Hospital Associate Professor, 医学部・附属病院, 助教授 … More 1999 – 2000: 新潟大学, 医学部・附属病院, 講師 1997 – 1998: 新潟大学, 医学部, 助手 1995: NIIGATA UNIVERSITY SCHOOL OF MEDICINE,DEPARTMENT OF ORTHOPAEDIC SYRGERY,INSTRUCT, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Orthopaedic surgery / Orthopaedic surgery Except Principal Investigator Orthopaedic surgery
Keywords	Principal Investigator mdm2 / cdk4 / p53 / DDR1 / SOD / u-PA / DNA microarray / ALP / PCR-ELISA / 末梢血 … More / Cbfa1 / 骨肉腫 / in situ PCR / 融合遺伝子 / 骨軟部肉腫 / 腫瘍特異的融合遺伝子 / RT-PCR / 循環微量腫瘍細胞 / バイオマーカー / 定量的RT-PCT / 血中循環腫瘍細胞 / osteosarcoma / ptk-3 / オキシジェンフリーラジカル / プラスミノーゲン / エストロゲン / 遺伝子発現 / DNAマイクロアレイ / DDRI / peripheral blood / 0sf2 / micro-metastasis / osteosarocma / 微少転移検出 / Cbfal / Osf2 / 微少転移 / aspiration biopsy cytology / bone and soft tissue tumors / cell culture / in situ hybrisization / in situ hybridization法 / 吸引細胞診 / 骨軟部腫瘍 / 培養細胞 / in situ hybridization / 定量的RT-PCR / 遺伝子増幅 / 血中循環微量腫瘍細胞 … More Except Principal Investigator parathyroid hormone / tail suspension / cartilage / differentiation / fet degeneration / osteonecrosis / adipocytes / bone marrow-derived mesenchymal cells / PPAR / 副甲状腺ホルモン / 尾部懸垂 / 軟骨 / 分化 / 脂肪変性 / 骨壊死 / 脂肪細胞 / 骨髄間葉系細胞 / ENZYME INDUCTION / DIHYDROFOLATE REDUCTASE / METHOTREXATE / DRUG RESISTANCE / CELL CULTURE / OSTEOSARCOMA / 酵素誘導 / ジヒドロフォレートリダクターゼ / メソトレキセート耐性 / 細胞培養 / 骨肉腫 / HLA class-1 / LAK活性 / メソトレキセート Less

骨軟部肉腫における血中循環腫瘍細胞の新規検出法による予後予測Principal Investigator
- Principal Investigator
  
  堀田哲夫
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Niigata University
Detection of circulating tumor cells targeting tumor specific fusion gene in musculoskeletal sarcomaPrincipal Investigator
- Principal Investigator
  
  Hotta Tetsuo
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Niigata University
An analysis of gene expression profile of osteosarcoma cells in the bone and peripheral blood with DNA microarray. -Identification of marker genes for osteosarcoma using hierarchical clustering algorithm. -Principal Investigator
- Principal Investigator
  
  HOTTA Tetsuo
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  NIIGATA UNIVERSITY
Analysis of the differentiation mechanism of human bone marrow derived osteoprogenitor cells
- Principal Investigator
  
  ENDO Naoto
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  NIIGATA UNIVERSITY
Investigation of osteosarocma specific marker for detection of micro-metastasisPrincipal Investigator
- Principal Investigator
  
  HOTTA Tetsuo
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  NIIGATA UNIVERSITY
PREOPERATIVE CYTOLOGICAL DIAGNOSIS FOR BONE AND SOFT TISSUE SARCOMAS USING IN SITUHYBRIDIZATION AND IN SITUPCR.Principal Investigator
- Principal Investigator
  
  HOTTA Tetsuo
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  NIIGATA UNIVERSITY
メソトレキセートがヒト骨肉腫細胞に対するLymphokine Activated Killer活性におよぼす影響
- Principal Investigator
  
  星栄一
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Niigata University
MECHANISM OF DRUG RESISTANCE OF METHOTREXATE IN OSTEOSARCOMA CELLS
- Principal Investigator
  
  TAKAHASHI Hideaki
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  NIIGATA UNIVERSITY SCHOOL OF MEDICINE

All 2018 2017 2016 2015 2013

All Journal Article Presentation

[Journal Article] The Diagnostic and Prognostic Value of Hematological and Chemical Abnormalities in Soft Tissue Sarcoma : A Comparative Study in Patients with Benign and Malignant Soft Tissue Tumors.2018
- Author(s)
  Ariizumi T, Kawashima H, Ogose A, Sasaki T, Hotta T, Hatano H, Morita T, Endo N.
- Journal Title
  
  Ann Clin Lab Sci.
  
  Volume: 48 Pages: 11-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10849
[Journal Article] The Diagnostic and Prognostic Value of Hematological and Chemical2018
- Author(s)
  Ariizumi T, Kawashima H, Ogose A, Sasaki T, Hotta T, Hatano H, Morita T, Endo
- Journal Title
  
  Ann Clin Lab Sci
  
  Volume: 48 Pages: 11-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10849
[Journal Article] Receptor-Activator of Nuclear KappaB Ligand Expression as a New Therapeutic Target in Primary Bone Tumors2016
- Author(s)
  Yamagishi T, Kawashima H, Ogose A, Ariizumi T, Sasaki T, Hatano H, Hotta T, Endo N
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 5 Pages: e0154680-e0154680
- DOI
  10.1371/journal.pone.0154680
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10849
[Journal Article] Effect of temozolomide on the viability of musculoskeletal sarcoma cells.2015
- Author(s)
  Kusabe Y, Kawashima H, Ogose A, Sasaki T, Ariizumi T, Hotta T, Endo N.
- Journal Title
  
  Oncology letters
  
  Volume: 10 Pages: 2511-2518
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25462325
[Journal Article] Telomelysin shows potent antitumor activity through apoptotic and non-apoptotic cell death in soft tissue sarcoma cells.2013
- Author(s)
  Li GD, Kawashima H, Ogose A, Ariizumi T, Hotta T, Kuwano R, Urata Y, Fujiwara T, Endo N
- Journal Title
  
  Cancer Science
  
  Volume: 104 Issue: 9 Pages: 1178-1188
- DOI
  10.1111/cas.12208
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462325
[Presentation] 良悪性境界病変に対する治療戦略デスモイド以外の中間性軟部腫瘍に対する分子細胞遺伝学的診断2018
- Author(s)
  川島寛之, 生越章, 有泉高志, 山岸哲郎, 大池直樹, 堀田哲夫, 遠藤直人, 佐々木太郎, 畠野宏史
- Organizer
  第67回東日本整形災害外科学会
- Data Source
  KAKENHI-PROJECT-16K10849
[Presentation] 脂肪系腫瘍の鑑別における微量検体からのRNAを用いたreal-time PCRによる遺伝子発現の有用性2017
- Author(s)
  山岸哲郎, 川島寛之, 生越章, 有泉高志, 大池直樹, 佐々木太郎, 畠野宏史, 堀田哲夫, 遠藤直人
- Organizer
  第50回日本整形外科学会骨・軟部腫瘍学術集会
- Data Source
  KAKENHI-PROJECT-16K10849
[Presentation] 骨・軟部腫瘍におけるスタニオカルシン-1の発現2017
- Author(s)
  山岸哲郎, 川島寛之, 有泉高志, 生越章, 大池直樹, 佐々木太郎, 畠野宏史, 堀田哲夫, 遠藤直人
- Organizer
  第32回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-16K10849
[Presentation] 骨・軟部腫瘍におけるスタニオカルシンー１の発現2016
- Author(s)
  川島寛之、山岸哲郎、有泉高志、堀田哲夫、遠藤直人、生越章
- Organizer
  第31回日本整形外科学会基礎学術集会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-16K10849
[Presentation] 針生検での微量検体RNAを用いたreal-time PCRによる遺伝子解析　脂肪腫と高分化型脂肪肉腫の比較2016
- Author(s)
  佐々木太郎、畠野宏史、大池直樹、小林宏人、川島寛之、有泉高志、山岸哲郎、堀田哲夫、生越章、遠藤直人
- Organizer
  第49回日本整形外科学会　骨・軟部腫瘍学術集会
- Place of Presentation
  東京ドームホテル（東京都文京区）
- Year and Date
  2016-07-14
- Data Source
  KAKENHI-PROJECT-16K10849
[Presentation] 軟部腫瘍における治療標的としてのRANKL関連分子の発現解析2015
- Author(s)
  山岸哲郎, 生越章, 川島寛之, 佐々木太郎, 堀田哲夫, 遠藤直人, 梅津哉, 畠野宏史, 有泉高志
- Organizer
  第30回日本整形外科学会基礎学術集会
- Place of Presentation
  富山国際会議場（富山県・富山市）
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-25462325
[Presentation] 脂肪腫と高分化型脂肪肉腫に対する針生検での微量検体RNAを用いたreal-time PCRによる遺伝子解析2013
- Author(s)
  佐々木太郎, 生越章, 川島寛之, 有泉高志, 堀田哲夫, 田中恵子, 遠藤直人
- Organizer
  第46回日本整形外科学会　骨・軟部腫瘍学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25462325

1. KAWASHIMA Hiroyuki (30361900)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
2. TAKAHASHI Hideaki (50018397)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. ENDO Naoto (10251810)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. TOKUNAGA Kurihiko (60323987)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 星栄一 (60081791)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. SASAKI Taro

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. YAMAGISHI Tetsuro

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

Hotta Tetsuo 堀田 哲夫

堀田 哲夫 ホツタ テツオ

HOTTA Tetsuo 堀田 哲夫

Research Projects

Research Products

Co-Researchers

骨軟部肉腫における血中循環腫瘍細胞の新規検出法による予後予測Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Detection of circulating tumor cells targeting tumor specific fusion gene in musculoskeletal sarcomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

An analysis of gene expression profile of osteosarcoma cells in the bone and peripheral blood with DNA microarray. -Identification of marker genes for osteosarcoma using hierarchical clustering algorithm. -Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of the differentiation mechanism of human bone marrow derived osteoprogenitor cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation of osteosarocma specific marker for detection of micro-metastasisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

PREOPERATIVE CYTOLOGICAL DIAGNOSIS FOR BONE AND SOFT TISSUE SARCOMAS USING IN SITUHYBRIDIZATION AND IN SITUPCR.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

メソトレキセートがヒト骨肉腫細胞に対するLymphokine Activated Killer活性におよぼす影響

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

MECHANISM OF DRUG RESISTANCE OF METHOTREXATE IN OSTEOSARCOMA CELLS

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] The Diagnostic and Prognostic Value of Hematological and Chemical Abnormalities in Soft Tissue Sarcoma : A Comparative Study in Patients with Benign and Malignant Soft Tissue Tumors.2018

Author(s)

Journal Title

Data Source

[Journal Article] The Diagnostic and Prognostic Value of Hematological and Chemical2018

Author(s)

Journal Title

Data Source

[Journal Article] Receptor-Activator of Nuclear KappaB Ligand Expression as a New Therapeutic Target in Primary Bone Tumors2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effect of temozolomide on the viability of musculoskeletal sarcoma cells.2015

Author(s)

Journal Title

Data Source

[Journal Article] Telomelysin shows potent antitumor activity through apoptotic and non-apoptotic cell death in soft tissue sarcoma cells.2013

Author(s)

Journal Title

DOI

Data Source

[Presentation] 良悪性境界病変に対する治療戦略 デスモイド以外の中間性軟部腫瘍に対する分子細胞遺伝学的診断2018

Author(s)

Organizer

Data Source

Hotta Tetsuo 堀田哲夫

堀田哲夫ホツタテツオ

HOTTA Tetsuo 堀田哲夫

[Presentation] 良悪性境界病変に対する治療戦略デスモイド以外の中間性軟部腫瘍に対する分子細胞遺伝学的診断2018

[Presentation] 針生検での微量検体RNAを用いたreal-time PCRによる遺伝子解析　脂肪腫と高分化型脂肪肉腫の比較2016