Shirasaka Tetsuro 白阪哲朗

… Alternative Names

SHIRASAKA Tetsuro 白阪哲朗

白坂哲朗シラサカテツロウ

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Researcher Number	00274788
Other IDs
Affiliation (Current)	2025: 宮崎大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2010 – 2014: 宮崎大学, 医学部, 准教授 2005 – 2009: University of Miyazaki, Department of medicine, Instructor, 医学部, 講師 2003 – 2004: 宮崎大学, 医学部, 助手 2002: 宮崎医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Anesthesiology/Resuscitation studies / Anesthesiology/Resuscitation studies Except Principal Investigator Anesthesiology/Resuscitation studies / Environmental physiology (including Physical medicine and Nutritional physiology) / Environmental physiology (including Physical medicine and Nutritional physiology)
Keywords	Principal Investigator オレキシン / 麻酔 / 視床下部室傍核 / Membrane Current / α2-agonist / Potassium channel / PVN / Orexin / Dexmedetomidine / GIRK … More / G1RL / カリウムチャネル / デクスメデトミジン / α2作動薬 / カリウムチャンネル / 膜電流 / オレキシン受容体 / グルタミン / モノアミン / 睡眠と覚醒 / 生理活性 / 生理学 / 薬理学 / 脳・神経 / ヒスタミン / 5-HT / マイクロダイアリシス / 覚醒 / 麻酔薬 / 麻酔学 / プロポフオール / 脳スライス / 電位依存性Ca電流 / Cl電流 / GABA / パッチクランプ法 / プロポフォール … More Except Principal Investigator paraventricular nucleus / hypertonic saline / 心血管系 / ニューロメジンU / Stress / 視床下部室傍核 / バゾプレッシン / 高張食塩水 / 免疫組織化学 / 局所麻酔薬 / vasopressinlb receptor / neuropeptide W / neuromedin U / CRF / vasopressin / Fos-like immunoreactivitv / 電気生理 / 単一神経活動 / ラット / オレキシン / ノックアウト動物 / 単一ユニット活動記録 / 自由行動・意識下 / パゾプレッシン1bレセプター / ニューロペプチドW / CRH / 浸透圧負荷 / パゾプレッシン / Ropivacaine / Levobupivacaine / Differential nerve block / Local anesthetics / ロピバカイン / レボブピバカイン / 分離神経ブロック / methacrylic acid / blood level / quartz crystal microbalance / propofol / molecularly imprinted polymer / ethacrylic acid / メタクリル酸 / 血中濃度測定 / 水晶振動子マイクロバランス / 分子刷り込みポリマー / プロポフォール / brain slice / NO / in vivo microdialysis / Vasopressin / Fos-immunohistochemical / I_h電流 / パッチクランプ法 / 脳スライス実験 / 交感神経活動 / 自由行動・意識下ラット / 脳スライス標本 / 一酸化窒素(NO) / in vivoマイクロダイアリシス / プロカイン / 癌抑制遺伝子 / リドカイン / DNA脱メチル化 Less

局所麻酔薬のDNA脱メチル化による腫瘍細胞増殖抑制および致死機序の解明
- Principal Investigator
  
  鬼塚信
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  University of Miyazaki
Analysis of orexin-receptor functionsPrincipal Investigator
- Principal Investigator
  
  SHIRASAKA Tetsuro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  University of Miyazaki
Effects of anesthetics on orexin cell-Is orexin system a target of anesthetics-Principal Investigator
- Principal Investigator
  
  SHIRASAKA Tetsuro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  University of Miyazaki
Effects of anesthetics on the release of orexin in conscious ratsPrincipal Investigator
- Principal Investigator
  
  白阪哲朗
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  University of Miyazaki
Modulation of central sodium / osmo-homeostatic mechanisms by novel peptides-Integrative studies
- Principal Investigator
  
  KANNAN Hiroshi
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Environmental physiology (including Physical medicine and Nutritional physiology)
- Research Institution
  University of Miyazaki
The interaction of dexmedetomidine and orexin 葉he mechanism of hypnosis and awake-Principal Investigator
- Principal Investigator
  
  SHIRASAKA Tetsuro
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  University of Miyazaki
Preparation of molecularly imprinted polymer sensor for blood level measurement of intravenous anesthetic.
- Principal Investigator
  
  IBUSUKI Shoichiro
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  University of Miyazaki
Studies of local anesthetic action
- Principal Investigator
  
  TAKASAKI Mayumi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  University OF Miyazaki
プロポフォールの交感神経抑制作用に関する研究Principal Investigator
- Principal Investigator
  
  白阪哲朗
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  宮崎医科大学
Integrative studies on central osmolality receptive mechanisms : Modification by novel peptides and environmental stress
- Principal Investigator
  
  KANNAN Hiroshi
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Environmental physiology (including Physical medicine and Nutritional physiology)
- Research Institution
  University of Miyazaki
  宮崎医科大学

All 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 Other

All Journal Article Presentation Book

[Book] 臨床麻酔の疑問に答える生理学オレキシンとはなにか2006
- Author(s)
  白阪哲朗
- Total Pages
  2
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-17591642
[Book] Hypocretins integrators of physiological functions.[分担]The hypocretins in cardiovascular regulation2005
- Author(s)
  Shirasaka, T., Kannan, H.
- Publisher
  Springer-Verlag
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390061
[Book] The hypocretins in cardiovascular regulation. In Hypocretins integrators of physiological functions., (Luis de Lecea, J.Gregor Sutcliffe (Eds.))2005
- Author(s)
  Shirasaka, T. et al.
- Publisher
  Springer-Verlag
- Data Source
  KAKENHI-PROJECT-17390061
[Journal Article] Effects of Orexin-A on propofol anesthesia in rats2011
- Author(s)
  Shirasaka T, YonahaT, Onizuka S, Tsuneyoshi I
- Journal Title
  
  J.Anesth.
  
  Volume: 25 Pages: 65-71
- NAID
  10029021845
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591979
[Journal Article] Capsaisin indirectly suppresses voltage-gated Na+ currents through TRPV1 in rat dorsal root ganglion neurons2011
- Author(s)
  Onizuka S, Yonaha T, Tamura R, Hosokawa N, Kawasaki Y, Kashiwada M, Shirasaka T, Tsuneyoshi I
- Journal Title
  
  Anesth Analg
  
  Volume: 112 Pages: 703-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591979
[Journal Article] Effects of Orexin-A on propofol anesthesia in rats.2011
- Author(s)
  Shirasaka T, Yonaha T, Onizuka S, Tsuneyoshi I.
- Journal Title
  
  J.Anesth.
  
  Volume: 25 Pages: 65-71
- NAID
  10029021845
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591979
[Journal Article] Effects of orexin-A on propofol anesthesia in rats2011
- Author(s)
  Shirasaka T, Yonaha T, Onizuka S, Tsuneyoshi I
- Journal Title
  
  J Anesth
  
  Volume: 25 Pages: 65-71
- NAID
  10029021845
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591979
[Journal Article] Effects of a novel isoindolin-1-one derivate, JM-1232(-), on cardiovascular and sympathetic functions in conscious rats2009
- Author(s)
  Shirasaka T, Kunitake T, Tsuneyoshi I.
- Journal Title
  
  Brain Res 1300
  
  Pages: 105-113
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591979
[Journal Article] Activation of a G-protein-coupled inwardly rectifying K^+ current and suppression of I_h contribute to dexmedetomidine-induced inhibition of rat hypothalamic paraventricular nucleus neurons2007
- Author(s)
  Tetsuro Shirasaka
- Journal Title
  
  Anesthesiology (In press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591642
[Journal Article] Activation of a G-protein coupled inwardly rectifying K current and suppression of Ih contribute to dexmedetomidine-induced inhibition of rat hypothalamic paraventricular nuleus neurons2007
- Author(s)
  Shirasaka T, Kannan H, Takasaki M
- Journal Title
  
  Anesthesiology 107
  
  Pages: 605-615
- Data Source
  KAKENHI-PROJECT-19591808
[Journal Article] The effects of centrally administered dexmedetomidine on cardiovascular and sympatrhetic function in conscious rats2007
- Author(s)
  Shirasaka T, Qiu DL, Kannan H, Takasaki M
- Journal Title
  
  Anesth. Analg 105
  
  Pages: 1722-1728
- Data Source
  KAKENHI-PROJECT-19591808
[Journal Article] 痛みとデクスメデトミジン2006
- Author(s)
  白阪哲朗, 高崎眞弓
- Journal Title
  
  ペインクリニック 27
  
  Pages: 1189-95
- Data Source
  KAKENHI-PROJECT-17591642
[Journal Article] The hypocretins in cardiovascular regulation. In Hypocretins integrators of physiological functions., Luis de Lecea, J. Gregor Surcliffe(Eds.)2005
- Author(s)
  Shirasaka, T., Kannan., H
- Journal Title
  
  Springer-Verlag
  
  Pages: 423-433
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390061
[Journal Article] Neuromedin U receptor-2 mRNA and HCN channels mRNA expression in NMU-sensitive neurons in rat hypothalamic paraventricular nucleus.2005
- Author(s)
  Qiu, D.-L, Chu, C.-P, Tsukino, H., Shirasaka, T., Nakao, H., Kato, K., Kunitake, T., Katoh, T., Kannan, H.
- Journal Title
  
  Neurosci.Lett. 374
  
  Pages: 69-72
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370024
[Journal Article] Effect of hypertonic saline on rat hypothalamic paraventricular nucleus magnocellular neurons in vitro.2004
- Author(s)
  Qiu, D.-L, Shirasaka, T., Chu, C.-P., Watanabe, S., Yu, N.-S., Katoh, T., Kannan, H.
- Journal Title
  
  Neurosci.Lett. 355
  
  Pages: 117-120
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370024
[Journal Article] Cardiovascular effects of leptin and orexins.2003
- Author(s)
  Shirasaka, T.et al.
- Journal Title
  
  Am.J.Physiol. 284
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370024
[Journal Article] Neuromedin U depolarizes rat hypothalamic paraventricular nucleus neurons in vitro by enhancing I_H channel activity.2003
- Author(s)
  Qiu, D.-L, Chu, C.-P., Shirasaka, T., Nabekura, T., Kunitake, T., Kato, K., Nakazato, M., Katoh, T., Kannan, H.
- Journal Title
  
  J.Neurophysiol. 90
  
  Pages: 843-850
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370024
[Journal Article] Cardiovascular effects of leptin and orexins.2003
- Author(s)
  Shirasaka, T., Takasaki, M., Kannan, H.
- Journal Title
  
  Am.J.Physiol. 284
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370024
[Journal Article] Neuronal effects of orexins : relevant to sympathetic and cardiovascular functions.2002
- Author(s)
  Shirasaka, T., Kunitake, T., Takasaki, M., Kannan, H.
- Journal Title
  
  Regul.Pept. 104
  
  Pages: 91-95
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370024
[Journal Article] Neuronal effects of orexins : relevant to sympathetic and cardiovascular functions.2002
- Author(s)
  Shirasaka, T.et al.
- Journal Title
  
  Regul.Pept. 104
  
  Pages: 91-95
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370024
[Journal Article] Activation of a G-protein-coupled inwardly rectifying K+ current and suppression of Ih contribute to dexmedetomidine-induced inhibition of rat hypothalamic paraventricular nucleus neurons
- Author(s)
  Tetsuro Shirasaka
- Journal Title
  
  Anesthesiology 2007 (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591642
[Presentation] レミフェンタニルの意識下ラットにおける心血管系および交感神経活動に及ぼす影響2011
- Author(s)
  白阪哲朗、日高康太郎、小田麻由、矢野武志、恒吉勇男
- Organizer
  日本麻酔科学会第58回学術集会
- Place of Presentation
  神戸市
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-21591979
[Presentation] レミフェンタニルの意識下ラットにおける心血管系および交感神経活動に及ぼす影響2011
- Author(s)
  白阪哲朗
- Organizer
  第58回日本麻酔科学会
- Place of Presentation
  神戸国際会議場神戸市
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-21591979
[Presentation] オレキシンのプロポフォール麻酔に及ぼす影響2010
- Author(s)
  白阪哲朗、須江宣俊、山賀昌治、田中信彦、恒吉勇男
- Organizer
  日本麻酔科学会第57回学術集会
- Place of Presentation
  福岡市
- Year and Date
  2010-06-03
- Data Source
  KAKENHI-PROJECT-21591979
[Presentation] オレキシンのプロポフォール麻酔に及ぼす影響2010
- Author(s)
  白阪哲朗
- Organizer
  第57回日本麻酔科学会
- Place of Presentation
  福岡国際会議場福岡県
- Data Source
  KAKENHI-PROJECT-21591979
[Presentation] The effects of Dexmedetomidine on the rat hypothalamic paraventricular nucleus neurons2008
- Author(s)
  Tetsuro Shirasaka. Masahiko Taniguchi. Isao Tsuneyoshi
- Organizer
  Annual meeting of American Society of Anesthesiologist meeting of American Society of Anesthesiologist 2008
- Place of Presentation
  Florida, Orland, U.S.A.
- Data Source
  KAKENHI-PROJECT-19591808
[Presentation] The effects of Dexmedetomidine on the rat hypothalamic paraventricular nucleus neurons2008
- Author(s)
  Tetsuro Shirasaka
- Organizer
  2008 Annual meeting of American Society of Anesthesiologist
- Place of Presentation
  Florida, Orland, U.S.A.
- Year and Date
  2008-10-19
- Data Source
  KAKENHI-PROJECT-19591808

1. KUNITAKE Takato (20234461)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
2. YONAHA Tetsu (70468023)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
3. KANNAN Hiroshi (00049058)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
4. KATO Kazuo (80284834)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
5. ISHIZUKA Yuta (20264377)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. YANO Takeshi (80521707)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. IBUSUKI Shoichiro (70315381)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. TAKASAKI Mayumi (30094212)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. TANAKA Nobuhiko (30264394)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. MATSUOKA Hiroshi (30315379)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 鬼塚信 (20264393)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 田村隆二 (40549060)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Shirasaka Tetsuro 白阪 哲朗

SHIRASAKA Tetsuro 白阪 哲朗

白坂 哲朗 シラサカ テツロウ

Research Projects

Research Products

Co-Researchers

局所麻酔薬のDNA脱メチル化による腫瘍細胞増殖抑制および致死機序の解明

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of orexin-receptor functionsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effects of anesthetics on orexin cell-Is orexin system a target of anesthetics-Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effects of anesthetics on the release of orexin in conscious ratsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Modulation of central sodium / osmo-homeostatic mechanisms by novel peptides-Integrative studies

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The interaction of dexmedetomidine and orexin 葉he mechanism of hypnosis and awake-Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Preparation of molecularly imprinted polymer sensor for blood level measurement of intravenous anesthetic.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies of local anesthetic action

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

プロポフォールの交感神経抑制作用に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Integrative studies on central osmolality receptive mechanisms : Modification by novel peptides and environmental stress

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 臨床麻酔の疑問に答える生理学 オレキシンとはなにか2006

Author(s)

Total Pages

Publisher

Data Source

[Book] Hypocretins integrators of physiological functions.[分担]The hypocretins in cardiovascular regulation2005

Author(s)

Publisher

Description

Data Source

[Book] The hypocretins in cardiovascular regulation. In Hypocretins integrators of physiological functions., (Luis de Lecea, J.Gregor Sutcliffe (Eds.))2005

Author(s)

Publisher

Data Source

Shirasaka Tetsuro 白阪哲朗

SHIRASAKA Tetsuro 白阪哲朗

白坂哲朗シラサカテツロウ

[Book] 臨床麻酔の疑問に答える生理学オレキシンとはなにか2006