MICHIKAWA Hiromi 関広美

… Alternative Names

関広美セキヒロミ

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Researcher Number	00277477
Affiliation (Current)	2025: 東邦大学, 薬学部, 講師
Affiliation (based on the past Project Information) *help	2006 – 2007: 東邦大学, 薬学部, 講師 2004 – 2005: 日本大学, 松戸歯学部, 助手 1999 – 2002: 日本大学, 松戸歯学部, 副手
Review Section/Research Field	Principal Investigator Functional basic dentistry Except Principal Investigator Functional basic dentistry / General pharmacology / Functional basic dentistry
Keywords	Principal Investigator カルシウムイオン / 唾液腺 / サイクリックGMP / ホスホジエステラーゼ Except Principal Investigator cGMP / Rho / 開口放出 / 耳下腺 / ICI-118,551 / Raft … More / 唾液腺 / 一酸化窒素合成酵素 / 一酸化窒素 / potassium channel / cyclic AMP / atenolol / β3-adrenocentors / relaxant response / vascular smooth muscle / β-adrenocentors / プロプラノロール / ブプラノロール / 胸部大動脈 / ラット血管平滑筋 / Kチャネル / サイクリックAMP / アテノロール / β_3-アドレナリン受容体 / 弛緩反応 / 血管平滑筋 / β-アドレナリン受容体 / Membrane domains / Nitric oxide synthase / Aquaporin / Secretory granules / Primary culture / Submandibular gland / Parotid gland / AQP / シンタキシン6 / Rac / cAMPホスホジエステラーゼ / 膜ドメイン / アクアポリン / 分泌顆粒 / 初代培養 / 顎下腺 / exocytosis / nitric oxide / syntaxin 1A / phospholipase D / inositol trisphosphate / sphingosine / salivary glands / Arf / アミラーゼ / cAMP / VAMP2 / イノシトール三リン酸 / スフィンゴシン / シンタキシン1A / ホスホリパーゼD / CYCLIC GMP / CALMODULIN / CALCIUM / PAROTID GLAND / NITRIC OXIDE SYNTHASE / NITRIC OXIDE / SALIVARY GLANDS / リン脂質 / NOS / カルモジュリン / カルシウム / ホスホジエステラーゼ Less

Pharmacological identification of vascular smooth muscle β-adrenoceptors and clarification. of1heir physiological roles
- Principal Investigator
  
  KOIKE Katsuo
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Toho University
Relationship between proteins related to exocytosis regulation in salivary glands
- Principal Investigator
  
  SUGIYA Hiroshi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Nihon University
Interaction of molecules related to secretion in salivary glands
- Principal Investigator
  
  FURUYAMA Shunsuke
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Nihon University
唾液腺におけるサイクリックGMPの分解調節Principal Investigator
- Principal Investigator
  
  通川広美
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Nihon University
TARGET MOLECULES OF NITRIC OXIDE/CYCLIC GMP
- Principal Investigator
  
  SUGIYA Hiroshi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  NIHON UNIVERSITY SCHOOL DENTISTRY AT MATSUDO

All 2007 2006 2005

All Journal Article Presentation

[Journal Article] Pharmacological characterization of the β-adrenoceptor that mediates the relaxant response to noradrenaline in guinea-pig tracheal smooth muscle.2007
- Author(s)
  Tanaka Y, Yamashita Y, Michikawa H, Horinouchi T, Koike K.
- Journal Title
  
  Naunyn-Schmiedeberg's Archives of Pharmacology 375(1)
  
  Pages: 51-64
- Data Source
  KAKENHI-PROJECT-18590242
[Journal Article] Pharmacological characterization of the β-adrenoccptor that mediates the relaxant response to noradrenaline in guinea-pie tracheal smooth muscle2007
- Author(s)
  Tanaka Y, Yamashita Y, Michikawa H, Horinouchi T, Koike K.
- Journal Title
  
  Naunyn-Schmiedeberg's Archives of Pharmacology 375(1)
  
  Pages: 51-64
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590242
[Journal Article] Pharmacological characterization of the β-adrenoceptor that mediates the relaxant response to noradrenaline in guinea-pig tracheal smooth muscle.2007
- Author(s)
  Tanaka Y, Yamashita Y, Michikawa H, Horinouchi T. Koike K.
- Journal Title
  
  Naunyn-Schmiedeberg's Archives of Pharmacology 375(1)
  
  Pages: 51-64
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590242
[Journal Article] Pharmacological characterization of the β-adrenoceptor that mediates the relaxant response to noradrenaline in guinea-pig tracheal smooth muscle2007
- Author(s)
  Tanaka, Y., Yamashita, Y., Michikawa, H., Horinouchi, T., Koike, K
- Journal Title
  
  Naunyn-Schmiedeberg's Archives of Pharmacology 375(1)
  
  Pages: 51-64
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590242
[Journal Article] Effects of aging on aradrenoceptor mechanisms in the isolated mouse aortic preparation2006
- Author(s)
  Tanaka, Y., Funabiki, M., Michikawa, H., Koike K
- Journal Title
  
  Journal of Smooth Muscle Research 42(4)
  
  Pages: 131-138
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590242
[Journal Article] Effects of aging on α_1-adrenoceptor mechanisms in the isolated mouse aortic preparation.2006
- Author(s)
  Tanaka Y, Funabiki M, Michikawa H, Koike K.
- Journal Title
  
  Journal of Smooth Muscle Research 42(4)
  
  Pages: 131-138
- NAID
  110004851899
- Data Source
  KAKENHI-PROJECT-18590242
[Journal Article] Effects of aging on α_1-adrenoceptor mechanisms in the isolated mouse aortic preparation2006
- Author(s)
  Tanaka Y, Funabiki M, Michikawa H, Koike K.
- Journal Title
  
  Journal of Smooth Muscle Research 42(4)
  
  Pages: 131-138
- NAID
  110004851899
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590242
[Journal Article] Phosphodiesterases 1 and 2 regulate cellular cGMP level in rabbit submandibular gland cells2005
- Author(s)
  Michikawa H, et al.
- Journal Title
  
  Int J Biochem Cell Biol 37
  
  Pages: 876-886
- Data Source
  KAKENHI-PROJECT-16390534
[Journal Article] Phosphodiesterases 1 and 2 regulate cellular cGMP lelel in rabbit submandibular gland cells.2005
- Author(s)
  Michikawa H et al.
- Journal Title
  
  Int. J. Biochem. Cell Biol. 37(4)
  
  Pages: 876-86
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390534
[Journal Article] Phosphodiesterase 1 and 2 regulate cellular cGMP level in rabbit submandibular gland cells2005
- Author(s)
  Michikawa H, et al.
- Journal Title
  
  Int.J.Biochem.Cell Biol. 37
  
  Pages: 876-886
- Data Source
  KAKENHI-PROJECT-16390534
[Journal Article] Phosphodiesterases 1 and 2 regulate cellular cGMP level in rabbit submandibular gland cells.2005
- Author(s)
  Michikawa H, et al.
- Journal Title
  
  Int.J.Biochem.Cell Biol. 37(4)
  
  Pages: 876-886
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390534
[Journal Article] Argininosuccinate synthetase activity in parotid gland2005
- Author(s)
  Michikawa H, et al.
- Journal Title
  
  Int J Oral-Med Sci 4
  
  Pages: 47-51
- NAID
  130000652977
- Data Source
  KAKENHI-PROJECT-16390534
[Presentation] ラット腹部大動脈平滑筋のpropranolol感受性β-アドレナリン受容体サブタイプの薬理学的同定2007
- Author(s)
  高橋裕美、通川広美、松下真由美、粕谷善俊、田中芳夫、小池勝夫
- Organizer
  第9回応用薬理シンポジウム
- Place of Presentation
  東京都
- Year and Date
  2007-09-10
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590242
[Presentation] Pharmacological characteristics of β-adrenoceptor (β -AR) subtypes that mediate smooth muscle relaxation to isoprenaline (ISO) in rat thoracic aorta2007
- Author(s)
  Tanaka, Y., Miyagawa, M., Michikawa, H., Koike, K
- Organizer
  The 5th International Symposium on Receptor Mechanism, Signal Transduction and Drug Effects
- Place of Presentation
  Shizuoka-City
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590242
[Presentation] Studies on the subtype-specific functional coupling between β-adrenoceptor (β-AR) and potassium channel in rat aortic smooth muscle2007
- Author(s)
  Miyagawa, M., Matsushita, M., Michikawa, H., Tanaka, Y., Koike, K
- Organizer
  The 80th Annual Meeting of the Japanese Pharmacological Society
- Place of Presentation
  Nagoya-City
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590242
[Presentation] Pharmacological characteristics of β-adrenoceptor(β-AR)subtypes that mediate smooth muscle relaxation to isoprenaline(ISO)in rat thoracic aorta2007
- Author(s)
  Tanaka Y, Miyagawa M, Michikawa H, Koike K.
- Organizer
  The 5th International Symposium on Receptor Mechanism, Signal Transduction and Drug Effects
- Place of Presentation
  静岡市
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590242
[Presentation] Pharmacological characteristics of β-adrenoceptor(β-AR)subtypes that mediate smooth muscle relaxation to isoprenaline(ISO)in rat thoracic aorta.2007
- Author(s)
  Tanaka Y, Miyagawa M, Michikawa H, Koike K.
- Organizer
  The 5th International Symposium on Receptor Mechanism, Signal Transduction and Drug Effects
- Place of Presentation
  静岡市
- Data Source
  KAKENHI-PROJECT-18590242
[Presentation] ラット腹部大動脈平滑筋のpropranolol感受性β-アドレナリン受容体サブタイプの薬理学的同定2007
- Author(s)
  高橋裕美、通川広美、松下真由美、粕谷善俊、田中芳夫、小池勝夫
- Organizer
  第9回応用薬理シンポジウム
- Place of Presentation
  東京都
- Year and Date
  2007-09-10
- Data Source
  KAKENHI-PROJECT-18590242
[Presentation] Studies on the β-adrenoceptor subtypes and their signal transduction mechanisms involved in the relaxant responses of rat aortic smooth muscle to isoprenaline2007
- Author(s)
  Miyagawa, M., Matsushita, M., Michikawa, H., Tanaka, Y., Koike, K
- Organizer
  The 127th Annual Meeting of the Pharmaceutical Society of Japan
- Place of Presentation
  Toyama-City
- Year and Date
  2007-03-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590242
[Presentation] ラット大動脈平滑筋のイソプレナリンによる弛緩反応に関与するβ-アドレナリン受容体サブタイプとその分子機序に関する検討2007
- Author(s)
  宮川瑞穂、松下真由美、通川広美、田中芳夫、小池勝夫
- Organizer
  日本薬学会第127年会
- Place of Presentation
  富山市
- Year and Date
  2007-03-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590242
[Presentation] β-アドレナリン受容体を介した血管弛緩反応機構-受容体とKチャネルのサブタイプ特異的機能共役の可能性に関する検討-2007
- Author(s)
  宮川瑞穂、松下真由美、通川広美、田中芳夫、小池勝夫
- Organizer
  第80回日本薬理学会年会
- Place of Presentation
  名古屋市
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590242
[Presentation] Propranolol-sensitive (β-adrenoceptors in rat abdominal aortic smooth muscle2007
- Author(s)
  Takahashi, H., Michikawa, H., Matsushita, M., Kasuya, Y., Tanaka, Y., Koike, K
- Organizer
  The 9th Ohyo-Yakuri Symposium
- Place of Presentation
  Tokyo
- Year and Date
  2007-09-10
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590242
[Presentation] β-Adrenoceptor mechanisms in rat aortic smooth muscle : subtypes and molecular mechanisms of relaxant responses2006
- Author(s)
  Miyagawa, M., Matsushita, M., Michikawa, H., Tanaka, Y., Koike, K
- Organizer
  The 115th Kanto Area Meeting of the Japanese Pharmacological Society
- Place of Presentation
  Takasaki-City
- Year and Date
  2006-09-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590242
[Presentation] β-3-アドレナリン受容体と創薬2006
- Author(s)
  小池勝夫、通川広美、田中芳夫
- Organizer
  第50回日本薬学会関東支部大会
- Place of Presentation
  新潟市
- Year and Date
  2006-10-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590242
[Presentation] β3-Adrenoceptors and drug discovery2006
- Author(s)
  Koike, K., Michikawa, H., Tanaka, Y
- Organizer
  The 50th Kanto Area Meeting of the Pharmaceutical Society of Japan
- Place of Presentation
  Niigata-City
- Year and Date
  2006-10-14
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590242
[Presentation] ラット胸部大動脈のイソプレナリンによる弛緩反応に関与するβ-アドレナリン受容体サブタイプに関する薬理学的検討2006
- Author(s)
  宮川瑞穂、通川広美、田中芳夫、小池勝夫
- Organizer
  第48回日本平滑筋学会総会
- Place of Presentation
  岡山市
- Year and Date
  2006-07-20
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590242
[Presentation] ラット大動脈のβ-アドレナリン受容体機構-サブタイプと弛緩反応機序に関する検討-2006
- Author(s)
  宮川瑞穂、松下真由美、通川広美、田中芳夫、小池勝夫
- Organizer
  第115回日本薬理学会関東部会
- Place of Presentation
  高崎市
- Year and Date
  2006-09-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590242
[Presentation] Pharmacological identification of β-adrenoceptor subtypes that mediate isoprenaline-induced relaxation of rat thoracic aorta2006
- Author(s)
  Miyagawa, M., Michikawa, H., Tanaka, Y., Koike, K
- Organizer
  The 48th Annual Meeting of the Japan Society of Smooth Muscle Research
- Place of Presentation
  Okayama-City
- Year and Date
  2006-07-20
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590242

1. SUGIYA Hiroshi (20050114)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. YOSHIGAKI Junko (40256904)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. FURUYAMA Shunsuke (50050034)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. DOHKE Yoko (90307869)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KATSUMATA Osamu (70349968)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. KOIKE Katsuo (70147578)

# of Collaborated Projects: 1 results

# of Collaborated Products: 23 results
7. TANAKA Yoshio (60188349)

# of Collaborated Projects: 1 results

# of Collaborated Products: 23 results

MICHIKAWA Hiromi 関 広美

関 広美 セキ ヒロミ

Research Projects

Research Products

Co-Researchers

Pharmacological identification of vascular smooth muscle β-adrenoceptors and clarification. of1heir physiological roles

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Relationship between proteins related to exocytosis regulation in salivary glands

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Interaction of molecules related to secretion in salivary glands

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

唾液腺におけるサイクリックGMPの分解調節Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

TARGET MOLECULES OF NITRIC OXIDE/CYCLIC GMP

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Pharmacological characterization of the β-adrenoceptor that mediates the relaxant response to noradrenaline in guinea-pig tracheal smooth muscle.2007

Author(s)

Journal Title

Data Source

[Journal Article] Pharmacological characterization of the β-adrenoccptor that mediates the relaxant response to noradrenaline in guinea-pie tracheal smooth muscle2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Pharmacological characterization of the β-adrenoceptor that mediates the relaxant response to noradrenaline in guinea-pig tracheal smooth muscle.2007

Author(s)

Journal Title

Data Source

[Journal Article] Pharmacological characterization of the β-adrenoceptor that mediates the relaxant response to noradrenaline in guinea-pig tracheal smooth muscle2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Effects of aging on aradrenoceptor mechanisms in the isolated mouse aortic preparation2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Effects of aging on α_1-adrenoceptor mechanisms in the isolated mouse aortic preparation.2006

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Effects of aging on α_1-adrenoceptor mechanisms in the isolated mouse aortic preparation2006

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] Phosphodiesterases 1 and 2 regulate cellular cGMP level in rabbit submandibular gland cells2005

Author(s)

Journal Title

Data Source

[Journal Article] Phosphodiesterases 1 and 2 regulate cellular cGMP lelel in rabbit submandibular gland cells.2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Phosphodiesterase 1 and 2 regulate cellular cGMP level in rabbit submandibular gland cells2005

Author(s)

MICHIKAWA Hiromi 関広美

関広美セキヒロミ