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SATA MAKOTO  佐田 誠

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佐田 誠  サタ マコト

SATA Makoto  佐田 誠

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Researcher Number 00280892
Other IDs
Affiliation (Current) 2025: 国立研究開発法人国立循環器病研究センター, 病院, 室長
Affiliation (based on the past Project Information) *help 2022: 国立研究開発法人国立循環器病研究センター, 病院, 医長
2014: 国立循環器病研究センター, 病院, 医長
2011: 独立行政法人国立循環器病研究センター, 呼吸器科, 医長
2006: National Cardiovascular Center, Department of Internal Medicine, Physician-in-Chief, 臨床検査部細菌免疫検査室, 医長
2001 – 2005: Yamagata University of School of Medicine, Instructor, 医学部, 講師
2000 – 2001: 山形大学, 医学部, 助手
1996: Yamagata University School of Medicine, Instructor, 医学部, 助手
Review Section/Research Field
Principal Investigator
Respiratory organ internal medicine / Respiratory organ internal medicine
Except Principal Investigator
Respiratory organ internal medicine / Basic Section 53030:Respiratory medicine-related / Circulatory organs internal medicine / Respiratory organ internal medicine / General internal medicine (including Psychosomatic medicine)
Keywords
Principal Investigator
metastasis / lung adenocarcinoma / invasion / lung cancer / thymidine phosphorylase / integrin / clarithromycin / ADP-ribosylation factor 6(ARF6) / 細胞運動 / ADP-ribosylation factor 6 (ARF6) … More / 肺癌 / clearthromycin / clarithromycin (CAM) / invasiveness / thymidine phosphorylase (TP) / Clarithromycin / Thymidine phosphorylase / thvmidine phosphorvlase / ARF-GEP100 / actin / ADP-ribosvlation factor 6(ARF6) / 遺伝子発現 / 気道上皮細胞 / Interleukin-8(インターロイキン8) / 細胞骨格 / 転移 / 浸潤 / ハムスター / ブレオマイシン / 抗癌剤 / 肺線維症 / テロメラーゼ … More
Except Principal Investigator
Endothelial Injury / IPF / COPD / MafB / Reactive oxygen species / FLIP / doxorubicin / heart failure / cardiomyocyte / apoptosis / Fas / 酸化ストレス / 臨床病態 / 生体ガス / 呼気 / 皮膚ガス / 活性酸素 / 肺毛細血管内皮細胞機能障害 / 突発性肺線維症 / 慢性閉塞性肺疾患 / 123 I-MIBG肺シンチグラム / pulmonary emphysema / cigarette smoking / transcription factor / alveolar macrophage / 肺気腫 / 喫煙 / 転写因子 / 肺胞マクロファージ / Fas Ligand / reactive oxygen species / doxorubinlin / Fas ligand / Neutrophil elastase / Microtuble / Cellular detachment / Bronchial epithelial cells / Interleukin-8 / 細胞骨格 / タキン-ル / 好中球エラスターゼ / 微小管 / 細胞剥離 / 気管支上皮細胞 / インターロイキン8 / 嫌気性発酵 / 腸内嫌気性発酵 / 呼気低分子化合物 / 水素分子 / 抗酸化作用 / 代替医療 / 難消化性多糖類 / 食物繊維 / 呼気成分 / 呼気水素 / 急性一酸化炭素中毒 / モノクロタリン肺高血圧症 / 熱電型水素センサ / 水素水 / 水素ガス / 生活習慣 / 肺循環障害 / 水素 Less
  • Research Projects

    (12 results)
  • Research Products

    (32 results)
  • Co-Researchers

    (15 People)
  •  生体ガス中に含まれる活性酸素の非侵襲的実時間計測法の確立と臨床応用展開

    • Principal Investigator
      下内 章人
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53030:Respiratory medicine-related
    • Research Institution
      Chubu University
  •  Effects of unabsorbable fibers and foods on biogas in adult human

    • Principal Investigator
      SHIMOUCHI Akito
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      General internal medicine (including Psychosomatic medicine)
    • Research Institution
      National Cardiovascular Center Research Institute
  •  Breath hydrogen as a possible anti-oxidative stress marker against hydroxyl radicals

    • Principal Investigator
      SHIMOUCHI Akito
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      National Cardiovascular Center Research Institute
  •  The significance of endothelial cell dysfunction in pulmonary microvessels in chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis

    • Principal Investigator
      TAKABATAKE Noriaki
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Yamagata University
  •  Role of thymidine phosphorylase on invasive potential in lung adenocarcinomaPrincipal Investigator

    • Principal Investigator
      SATA Makoto
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      National Cardiovascular Center Research Institute
      Yamagata University
  •  Role of transcription factor MafB in alveolar macrophages of smoking-induced emphysema

    • Principal Investigator
      SHIBATA Yoko
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Yamagata University
  •  Roles of thymidine phosphorylase on invasiveness and metastasis in lung cancerPrincipal Investigator

    • Principal Investigator
      SATA Makoto
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Yamagata University
  •  肺癌の浸潤・転移におけるADPリボシル化因子6(ARF6)の役割の解明Principal Investigator

    • Principal Investigator
      佐田 誠
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Yamagata University
  •  Contibution of cardiomyocyte apoptosis to development of congestive heart failure

    • Principal Investigator
      YAMAGUCHI Seiji
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      First Department of Internal Medicine, Yamagata University School of Medicine
  •  Search for genes responding to mechanical detachment in bronchial epithelial cellsPrincipal Investigator

    • Principal Investigator
      SATA Makoto, 中村 秀範
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Yamagata University
  •  肺の線維化と発癌におけるテロメアとテロメラーゼの関与Principal Investigator

    • Principal Investigator
      佐田 誠
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Yamagata University
  •  Cellular Detachment and Deformation induce Cytokine Gene Expression in Human Bronchial Epithelial Cells

    • Principal Investigator
      NAKAMURA Hidenori
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Yamagata University

All 2007 2006 2005 2003 Other

All Journal Article

  • [Journal Article] Intronic single-nucleotide polymorphisms in Bc1-2 are associated with chronic obstructive pulmonary disease severity2007

    • Author(s)
      Sata M, et al.
    • Journal Title

      Respirology 12

      Pages: 34-41

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590779
  • [Journal Article] Enhanced expression of MafB inhibits macrophage apoptosis induced by cigarette smoke exposure.2007

    • Author(s)
      Machiya J, Shibata Y, Yamauchi K, Hirama N, Wada T, Inoue S, Abe S, Takabatake N, Sata M, Kubota I
    • Journal Title

      Am J Respir Cell Mol Biol 36

      Pages: 418-426

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590779
  • [Journal Article] Increased surfactant protein-D and foamy alveolar macrophages in smoking-induced mouse emphysema.2007

    • Author(s)
      Hirama N, Shibata Y, Otake K, Machiya J, Wada T, Inoue S, Abe S, Takabatake N, Sata M, Kubota I
    • Journal Title

      Respirology 12

      Pages: 191-201

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590779
  • [Journal Article] Intronic single-nucleotide polymorphisms in Bcl-2 are associated with chronic obstructive pulmonary disease severity.2007

    • Author(s)
      Sata M, Takabatake N, Inoue S, Shibata Y, Abe S, Machiya J, Wada T, Ji G, Kido T, Matsuura T, Muramatsu M, Kubota I
    • Journal Title

      Respirology 12

      Pages: 34-41

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590779
  • [Journal Article] Clarithromycin suppresses invasiveness of human lung adenocarcinoma cells2007

    • Author(s)
      Wada T, Sata M, et al.
    • Journal Title

      Chemotherapy 53

      Pages: 77-84

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590779
  • [Journal Article] Clarithromycin suppresses invasiveness of human lung adenocarcinoma cells.2007

    • Author(s)
      Wada T, Sata M, Sato J, Tokairin Y, Machiya J, Hirama N, Arao T, Inoue S, Takabatake N, Shibata Y, Kubota I
    • Journal Title

      Chemotherapy 53

      Pages: 77-84

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590779
  • [Journal Article] A single polymorphism in CCL1 gene predicts acute exacerbations in COPD.2006

    • Author(s)
      Takabatake N, Shibata Y, Abe S, Wada T, Machiya J, Igarashi A, Tokairin Y, Ji G, Sato H, Sata M, Takeishi Y, Emi M, Muramatsu M, Kubota I
    • Journal Title

      Am J Respir Crit Care Med 174

      Pages: 875-885

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590779
  • [Journal Article] Treatment and transfer of emphysema by a new bone marrow transplantation method from normal mice to Tsk mice and vice versa.2006

    • Author(s)
      Adachi Y, Oyaizu H, Taketani S, Minamino K, Yamaguchi K, Shultz LD, Iwasaki M, Tomita M, Suzuki Y, Nakano K, Koike Y, Yasumizu R, Sata M, Hirama N, Kubota I, Fukuhara S, Ikehara S
    • Journal Title

      Stem Cells 24

      Pages: 2071-2077

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590779
  • [Journal Article] Increased endothelin-1 levels of bronchoalveolar lavage fluid in patients with pulmonary sarcoidosis.2006

    • Author(s)
      erashita K, Kato S, Sata M, Inoue S, Nakamura H, Tomoike H
    • Journal Title

      Respirology 11

      Pages: 145-151

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590779
  • [Journal Article] Three cases of pulmonary actinomycosis diagnosed by fiberoptic bronchoscopy.2005

    • Author(s)
      Inoue S, Sata M, et al.
    • Journal Title

      J Bronchol 12・4

      Pages: 273-274

    • Data Source
      KAKENHI-PROJECT-17590779
  • [Journal Article] Enhanced expression of Aggrus (T1α/podoplanin), a platelet aggregation-inducing factor in lung squamous cell carcinoma.2005

    • Author(s)
      Kato Y, Kaneko M, Sata M, Fujita N, Tsuruo T, Osawa M
    • Journal Title

      Tumor Biol 26

      Pages: 195-200

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590779
  • [Journal Article] Impaired Systemic Cell-Mediated Immunity and Increased Susceptibility to Acute Respiratory Tract Infections in Patients with COPD2005

    • Author(s)
      Takabatake N, Sata M, et al.
    • Journal Title

      Respir Med 99

      Pages: 485-492

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590796
  • [Journal Article] A Novel Polymorphism in Secretory Phospholipase A_2 IID is Associated with Body Weight Loss in COPD.2005

    • Author(s)
      Takabatake N, Sata M, et al.
    • Journal Title

      Am J Respir Crit Care Med 172

      Pages: 1097-1104

    • Data Source
      KAKENHI-PROJECT-17590779
  • [Journal Article] Impaired systemic cell-mediated immunity and increased susceptibility to acute respiratory tract infections in patients with COPD.2005

    • Author(s)
      Takabatake N, Sata M, Abe S, Inoue S, Saito H, Yuki H, Shibata Y, Kubota I
    • Journal Title

      Resp Med 99

      Pages: 485-492

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590796
  • [Journal Article] Involvement of pulmonary endothelial cell injury in the pathogenesis of pulmonary fibrosis : clinical assessment by ^<123>I-MIBG lung scintigraphy.2005

    • Author(s)
      Takabatake N, Arao T, Sata M, Abe S, Inoue S, Shibata Y, Takeishi Y, Kubota I
    • Journal Title

      Eur J Nucl Med Imaging 32

      Pages: 221-228

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590796
  • [Journal Article] Circulating levels of soluble Fas ligand in cachexic patients with COPD are higher than those in non-cachexic patients with COPD.2005

    • Author(s)
      Takabatake N, Arao T, Sata M, Inoue S, Abe S, Shibata Y, Kubota I
    • Journal Title

      Intern Med 44

      Pages: 1137-1143

    • NAID

      10016885943

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590779
  • [Journal Article] A novel polymorphism in secretory phospholipase A_2-IID is : associated with body weight loss in COPD.2005

    • Author(s)
      Takabatake N, Sata M, Inoue S, Shibata Y, Abe S, Wada T, Machiya J, Ji G, Matsuura T, Takeishi Y, Muramatsu M, Kubota I
    • Journal Title

      Am J Respir Crit Care Med 172 (Originally published in press as DOI:10.1164/rccm.200503-3190C on July 7 2005)

      Pages: 1097-1104

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590779
  • [Journal Article] Involvement of pulmonary endothelial cell injury in the pathogenesis of pulmonary fibrosis : clinical assessment by ^<123>I-MIBG lung scintigraphy.2005

    • Author(s)
      Takabatake N, Arao T, Sata M, Abe S, Inoue S, Shibata Y, Honma T, Takahashi K, Okada A, Takeishi Y, Kubota I
    • Journal Title

      Eur J Nucl Med Mol Imaging 32

      Pages: 221-228

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590779
  • [Journal Article] Expression and Localization of Diacylglycerol Kinase Isozymes and Enzymatic Features in Rat Lung.2005

    • Author(s)
      Katagiri Y, Ito T, Saino-Saito S, Hozumi Y, Suwabe A, Otake K, Sata M, Kondo H, Sakane F, Kanoh H, Kubota I, Goto K
    • Journal Title

      Am J Physiol Lung Cell Mol Physiol 288

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590779
  • [Journal Article] Involvement of pulmonary endothelial cell injury in the pathogenesis of pulmonary fibrosis : clinical assessment by ^<123>I-MIBG lung scintigraphy2005

    • Author(s)
      Takabatake N, Arao T, Sata M, et al.
    • Journal Title

      Eur J Nucl Med Mol Imaging 32

      Pages: 221-228

    • Data Source
      KAKENHI-PROJECT-15590796
  • [Journal Article] Impaired systemic cell-mediated immunity and increased susceptibility to acute respiratory tract infections in patients with COPD.2005

    • Author(s)
      Takabatake N, Sata M, Abe S, Inoue S, Saito H, Yuki H, Shibata Y, Kubota I
    • Journal Title

      Respir Med 99

      Pages: 485-492

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590779
  • [Journal Article] Three cases of pulmonary actinomycosis diagnosed by fiberoptic bronchoscopy.2005

    • Author(s)
      Inoue S, Sata M, Inage M, Kato S, Kubota I
    • Journal Title

      J Bronchol 12

      Pages: 273-275

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590779
  • [Journal Article] Role of thymidine phosphorylase on invasiveness and metastasis in lung adenocarcinoma2003

    • Author(s)
      Sato J, Sata M, et al.
    • Journal Title

      Int J Cancer 106

      Pages: 863-870

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590796
  • [Journal Article] Antineutrophil cytoplasmic antibody positive alveolar haemorrhage during propylthiouracil therapy for hyperthyroidism2003

    • Author(s)
      Yamauchi K, Sata M, et al.
    • Journal Title

      Respirology 8

      Pages: 532-535

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590796
  • [Journal Article] Role of thymidine phosphorylase on invasiveness and metastasis in lung adenocarcinoma.2003

    • Author(s)
      Sato J, Sata M, Nakamura H, Inoue S, Wada T, Takabatake N, Otake K, Tomoike H, Kubota I
    • Journal Title

      Int J Cancer 106

      Pages: 863-870

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590796
  • [Journal Article] In vivo evidence of endothelial injury in chronic obstructive pulmonary disease by lung scintigraphic assessment of ^<123>I-metaiodobenzylguanidine2003

    • Author(s)
      Arao T, Takabatake N, Sata M, et al.
    • Journal Title

      J Nucl Med 44

      Pages: 1747-1754

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590796
  • [Journal Article] Antineutrophil cytoplasmic antibody positive alveolar haemorrhage during propylthiouracil therapy for hyperthyroidism.2003

    • Author(s)
      Yamauchi K, Sata M, Machiya J, Osaka D, Wada T, Abe S, Otake K, Kubota I
    • Journal Title

      Respirology 8

      Pages: 532-535

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590796
  • [Journal Article] In vivo evidence of endothelial injury in chronic obstructive pulmonary disease by lung scintigraphic assessment of ^<123>I-metaiodobenzylguanidine.2003

    • Author(s)
      Arao T, Takabatake N, Sata M, Abe S, Shibata Y, Honma T, Takahashi K, Okada A, Takeishi Y, Kubota I
    • Journal Title

      J Nucl Med 44

      Pages: 1747-1754

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590796
  • [Journal Article] Enhanced expression of Aggrus (T1α/podoplanin), a platelet aggregation-inducing factor in lung squamous cell carcinoma

    • Author(s)
      Kato Y, Kaneko M, Sata M, et al.
    • Journal Title

      Tumor Biol (in press)

    • Data Source
      KAKENHI-PROJECT-15590796
  • [Journal Article] Enhanced expression of Aggrus (T1α/podoplanin), a platelet aggregation-inducing factor in lung squamous cell carcinoma

    • Author(s)
      Kato Y, Kaneko M, Sata M, et al.
    • Journal Title

      Tumor Biol (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590796
  • [Journal Article] Clarithromycin suppresses invasiveness of human lung adenocarcinoma cells

    • Author(s)
      Wada T, Sata M, et al.
    • Journal Title

      Chemotherapy (In press)

    • Data Source
      KAKENHI-PROJECT-17590779
  • [Journal Article] Increased endothelin-1 levels of bronchoalveolar lavage fluid in patients with pulmonary sarcoidosis

    • Author(s)
      Terashita K, Kato S, Sata M, et al.
    • Journal Title

      Respirology (In press)

    • Data Source
      KAKENHI-PROJECT-17590779
  • 1.  SHIBATA Yoko (60333978)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 12 results
  • 2.  TAKABATAKE Noriaki (80344795)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 17 results
  • 3.  SHIMOUCHI Akito (80211291)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  KONDO Takaharu (20135388)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  NAKAMURA Hidenori (30240675)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  KATO Shuichi (90260463)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  TAKEISHI Yasuchika (40272067)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  MATSUBARA Ichiro (40344220)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  SHIN Wosuck (10357246)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  NISHIBORI Maiko (20462848)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  SHIRAI Mikiyasu (70162758)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  OTAKE Kazuhisa (30312739)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  YAMAGUCHI Seiji (30239892)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  YOSHIMURA Tetsuhiko (70271517)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  諏訪部 章 (20241713)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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