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Komine Mayumi  小宮根 真弓

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KOMINE Mayumi  小宮根 真弓

小宮根 真弓  コミネ マユミ

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Researcher Number 00282632
Other IDs
Affiliation (Current) 2025: 自治医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help 2018 – 2024: 自治医科大学, 医学部, 教授
2016 – 2017: 自治医科大学, 医学部, 准教授
2010 – 2013: 自治医科大学, 医学部, 准教授
2008: Jichi Medical University, 医学部・皮膚科学, 准教授
2007 – 2008: 東京大学, 医学部・附属病院, 講師 … More
2007 – 2008: Jichi Medical University, 医学部, 准教授
2004 – 2007: The University of Tokyo, Faculty of Medicine, Lecturer, 医学部附属病院, 講師
2002: 東京大学, 医学部附属病院, 講師
1998: 東京大学, 医学部・付属病院, 助手 Less
Review Section/Research Field
Principal Investigator
Dermatology / Dermatology / Basic Section 53050:Dermatology-related
Except Principal Investigator
Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Dermatology / Basic Section 53050:Dermatology-related / Dermatology / Pathological medical chemistry
Keywords
Principal Investigator
表皮細胞 / IL-33 / ケラチノサイト / ケモカイン / 炎症性皮膚疾患 / 炎症 / STAT1 / TARC / IL-33 / 転写因子 … More / CTACK / treatment / decubitus ulcer / ケラチン / 代謝 / マウスモデル / マクロファージ / 虚血再灌流モデル / 治療 / 中和抗体 / 核内因子 / 虚血再灌流 / 褥瘡 / 皮膚バリア機能 / 皮膚炎 / トランスジェニックマウス / 有棘層 / MAP kinases / Mechanical Stress / Inflammatory skin diseases / NF kappa B / CCL17 / Chemokines / Keratinocytes / デコイ型核酸 / HaCaT細胞 / MAPキナーゼ / 機械的刺激 / NFκB / シグナル伝達 / IL-17 / IFNγ / UVB / インターフェロンγ / 発現調節 / 表皮角化細胞 / 樹状細胞 / 発現制御機構 / 乾癬 / GM-CSF / VEGF / Groα / 臨床効果 / 尋常性乾癬 / マクロライド … More
Except Principal Investigator
サイトカイン / 皮膚疾患 / アトピー性皮膚炎 / 酵素阻害物質 / フラグメント分子軌道法 / コンドロイチン硫酸 / ヒアルロン酸 / ヘパラナーゼ / MEC / CTACK / TARC / ケモカイン / IL-33 / 樹状細胞 / ランゲルハンス細胞 / 細胞外分泌 / 転写調節 / スプライシングバリアント / 阻害剤 / 糖鎖創薬 / ターゲッティング / 融合タンパク質 / 抗体複合体 / へパリン / 酵素阻害剤 / 警告因子 / 硫酸化糖鎖 / アレルギー / マスト細胞 / ヘパリン / 角質細胞層 / NF-kappaB / 細胞外小胞 / ヘパラン硫酸 / 基底膜 / 細胞外マトリックス / 炎症 / アレルギー性皮膚炎 / psoriasis / Vitiligo / ultraviolet B / melanocytes / 紫外線治療 / 表皮角化細胞 / メラニン / メラニン代謝物質 / 紫外線療法 / 尋常性乾癬 / 尋常性白斑 / 紫外線 / メラノサイト / transgenic mice / Chemokine / Keratino cytes / Dendritic cells / Lagerhans cells / Toll-like recepter / Eotaxin-3 / トランスジェニックマウス / ケラチノサイト / リガンド / アレルギー疾患 / 免疫学 / タンパク質 / ST2 / シグナル伝達 / ST2遺伝子 / 活性化 / 抗原提示 / 共刺激分子 Less
  • Research Projects

    (13 results)
  • Research Products

    (250 results)
  • Co-Researchers

    (21 People)
  •  Search for novel IL-33 isoforms in inflammatory skin diseases and analysis of their relationship with pathology

    • Principal Investigator
      津田 英利
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53050:Dermatology-related
    • Research Institution
      Jichi Medical University
  •  Design of heparanase inhibitors focusing on molecular bending and competitive interaction: aiming to suppress skin inflammatory diseases

    • Principal Investigator
      東 伸昭
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
    • Research Institution
      Hoshi University
  •  Approach to treatment of decubitus ulcer by IL-33 inhibitionPrincipal Investigator

    • Principal Investigator
      Mayuim Komine
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53050:Dermatology-related
    • Research Institution
      Jichi Medical University
  •  Sulfated polysacharides exert biphasic regulations on inflammation and allergic skin diseases: roles of polysaccharide degradation

    • Principal Investigator
      Higashi Nobuaki
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
    • Research Institution
      Hoshi University
  •  The role of IL-33 in the dysfunction of skin barrierPrincipal Investigator

    • Principal Investigator
      Komine Mayumi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Jichi Medical University
  •  The role of IL-33 and its reseptor in contact hypersensitivity reactionPrincipal Investigator

    • Principal Investigator
      KOMINE Mayumi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Jichi Medical University
  •  The implication of conformational change of ST2 gene product due to polymorphism for various diseases.

    • Principal Investigator
      TOMINAGA Shinichi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Jichi Medical University
  •  Regulation of chemokine production in inflammatory cutaneous disordersPrincipal Investigator

    • Principal Investigator
      KOMINE Mayumi
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Jichi Medical University
      The University of Tokyo
  •  Investigation of Langerhans cell stimulatory molecule and its application in skin disease therapy

    • Principal Investigator
      TAMAKI Kunihiko
    • Project Period (FY)
      2005 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Dermatology
    • Research Institution
      The University of Tokyo
  •  The changes of cytologic features of melanocytes after verious treatments

    • Principal Investigator
      KIKUCHI Kanako
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      The University of Tokyo
  •  The rote of chemokine and dendritic cells in skin diseases

    • Principal Investigator
      TAMAKI Kunihiko
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Dermatology
    • Research Institution
      The University of Tokyo
  •  Basic Research for the Clinical Use of Nuclear Factor-binding DNA Decoy for Inflammatory Skin DiseasesPrincipal Investigator

    • Principal Investigator
      KOMINE Mayumi, 小宮根 真弓
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      The University of Tokyo
  •  尋常性乾癬に対するマクロライドの効果とその作用機序についてPrincipal Investigator

    • Principal Investigator
      小宮根 真弓, 小宮根 真弓
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Dermatology
    • Research Institution
      The University of Tokyo

All 2024 2023 2022 2021 2020 2018 2017 2016 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 Other

All Journal Article Presentation Book Patent Other

  • [Book] Keratinocyte Biology: structure and function in the epidermis2022

    • Author(s)
      Mayumi Komine
    • Total Pages
      118
    • Publisher
      InTech
    • ISBN
      9781803551005
    • Data Source
      KAKENHI-PROJECT-20K08661
  • [Book] Psoriasis2017

    • Author(s)
      Jitlada Meephansan, Urairack Subpayasarn, Mayumi Komine, and Mamitaro Ohtsuki
    • Publisher
      Intech
    • Data Source
      KAKENHI-PROJECT-16K10172
  • [Book] 転写因子と皮層の病態、ケラテノサイト:最新反層科字大糸 2008-2009 玉置邦彦 編2008

    • Author(s)
      小宮根 真弓
    • Total Pages
      9
    • Publisher
      中山書店
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Book] 毛孔性苔癬(2008今日の治療指針)2008

    • Author(s)
      小宮根真弓(総編集 山口徹、北原光夫、福井告次矢)
    • Publisher
      医学書院、東京
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Book] インターフェロンの使い方は?現場の疑問に答える皮膚病治療薬Q&A2008

    • Author(s)
      小宮根真弓(宮地良樹、大谷道輝 編)
    • Publisher
      中外医学社、東京
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Book] ここまでわかった乾癬の病態:WHATS NEW IN 皮膚科学2008-2009。宮地良樹 編2007

    • Author(s)
      小宮根 真弓
    • Total Pages
      2
    • Publisher
      メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Book] ジベルばら色ひこう疹、毛孔性紅ひこう疹:看護のための最新医学講座第二版第19巻皮膚科疾患 中川秀巳 編2007

    • Author(s)
      小宮根 真弓
    • Total Pages
      3
    • Publisher
      中山書店
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Book] ジベルばら色ひこう疹 看護のための最新医学講座第二版第19巻皮膚科疾患2007

    • Author(s)
      小宮根真弓(中川秀己編)
    • Publisher
      中山書店 東京
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Book] 毛孔性紅色ひこう疹 看護のための最新医学講座第二版第19巻皮膚科疾患2007

    • Author(s)
      小宮根真弓(中川秀己編)
    • Publisher
      中山書店 東京
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Book] かゆみに奏功する可能性のある既存薬、かゆみ最前線2006

    • Author(s)
      小宮根真弓(宮地良樹、生駒晃彦編)
    • Publisher
      メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Book] 皮膚疾患の最新医療、先端医療シリーズ38 皮膚科、マクロライド系薬剤の新たな効用、2006

    • Author(s)
      小宮根真弓, 玉置邦彦
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Book] かゆみ最前線 かゆみに奏功する可能性のある既存薬2006

    • Author(s)
      小宮根真弓
    • Total Pages
      207
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Book] マクロライドはかゆみに効くか、WHAT'S NEW IN皮膚科学2006-20072006

    • Author(s)
      小宮根真弓(宮地良樹編)
    • Publisher
      メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Book] ここまでわかった乾癬の病態(WHAT'S NEW IN 皮膚科学2008-2009)

    • Author(s)
      小宮根真弓(宮地良樹 編)
    • Publisher
      メディカルレビュー社、 東京
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] Elucidating the NB-UVB mechanism by comparing transcriptome alteration on the edge and center of psoriatic plaques2023

    • Author(s)
      Boonpethkaew Suphagan、Meephansan Jitlada、Charoensuksira Sasin、Jumlongpim Onjira、Tangtanatakul Pattarin、Wongpiyabovorn Jongkonnee、Komine Mayumi、Akimichi Morita
    • Journal Title

      Scientific Reports

      Volume: 13 Issue: 1 Pages: 4384-4384

    • DOI

      10.1038/s41598-023-31610-y

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08661
  • [Journal Article] Nuclear IL-33 regulates cytokinesis and cell motility in normal human epidermal keratinocytes2022

    • Author(s)
      Tsuda H., Tominaga S., Ohtsuki M., Komine M
    • Journal Title

      J Dertmatol Sci

      Volume: 105 Issue: 2 Pages: 113-120

    • DOI

      10.1016/j.jdermsci.2022.01.006

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K08678, KAKENHI-PROJECT-20K08661
  • [Journal Article] Immunotherapy for the Treatment of Squamous Cell Carcinoma: Potential Benefits and Challenges2022

    • Author(s)
      Ansary Tuba M.、Hossain MD Razib、Komine Mayumi、Ohtsuki Mamitaro
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 23 Issue: 15 Pages: 8530-8530

    • DOI

      10.3390/ijms23158530

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08661
  • [Journal Article] Case of psoriasis with hepatitis B virus infection during tumor necrosis factor inhibitor treatment successfully treated with ixekizumab and tenofovir alafenamide fumarate2022

    • Author(s)
      Kishimoto Megumi、Komine Mayumi、Kamiya Koji、Sugai Junichi、Kuwahara Aya、Morimoto Naoki、Ohtsuki Mamitaro
    • Journal Title

      The Journal of Dermatology

      Volume: 0 Issue: 6 Pages: 0-0

    • DOI

      10.1111/1346-8138.16320

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K08661
  • [Journal Article] Transcriptomic Profiling of Peripheral Edge of Lesions to Elucidate the Pathogenesis of Psoriasis Vulgaris2022

    • Author(s)
      Boonpethkaew Suphagan、Meephansan Jitlada、Jumlongpim Onjira、Tangtanatakul Pattarin、Soonthornchai Wipasiri、Wongpiyabovorn Jongkonnee、Vipanurat Ratchanee、Komine Mayumi
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 23 Issue: 9 Pages: 4983-4983

    • DOI

      10.3390/ijms23094983

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08661
  • [Journal Article] Diagnosis and Intervention in Early Psoriatic Arthritis.2022

    • Author(s)
      Hioki T, Komine M, Ohtsuki M
    • Journal Title

      J Clin Med

      Volume: 0 Issue: 7 Pages: 0-0

    • DOI

      10.3390/jcm11072051

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08661
  • [Journal Article] Estradiol suppresses psoriatic inflammation in mice by regulating neutrophil and macrophage functions2022

    • Author(s)
      Adachi Akimasa、Honda Tetsuya、Egawa Gyohei、Kanameishi Shuto、Takimoto Riko、Miyake Toshiya、Hossain Md Razib、Komine Mayumi、Ohtsuki Mamitaro、Gunzer Matthias、Ikuta Koichi、Kabashima Kenji
    • Journal Title

      Journal of Allergy and Clinical Immunology

      Volume: 150 Issue: 4 Pages: 909-919.e8

    • DOI

      10.1016/j.jaci.2022.03.028

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K08428, KAKENHI-PROJECT-20H03501, KAKENHI-PROJECT-20K08661, KAKENHI-PROJECT-20H05697
  • [Journal Article] Comparison of transcriptomic profiles in edge to center of plaque reveals chronological molecular events in psoriatic plaque formation2022

    • Author(s)
      Boonpethkaew Suphagan、Meephansan Jitlada、Jumlongpim Onjira、Charoensuksira Sasin、Tangtanatakul Pattarin、Wongpiyabovorn Jongkonnee、Komine Mayumi
    • Journal Title

      Journal of Dermatological Science

      Volume: 108 Issue: 1 Pages: 30-38

    • DOI

      10.1016/j.jdermsci.2022.10.003

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08661
  • [Journal Article] Inflammation Causes Exacerbation of COVID-19: How about Skin Inflammation?2022

    • Author(s)
      Komine Mayumi、Ansary Tuba Mussarat、Hossain Md Razib、Kamiya Koji、Ohtsuki Mamitaro
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 23 Issue: 20 Pages: 12260-12260

    • DOI

      10.3390/ijms232012260

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08661
  • [Journal Article] K15 promoter-driven enforced expression of NKIRAS exhibits tumor suppressive activity against the development of DMBA/TPA-induced skin tumors.2021

    • Author(s)
      Tago K, Ohta S, Aoki-Ohmura C, Funakoshi-Tago M, Sashikawa M, Matsui T, Miyamoto Y, Wada T, Oshio T, Komine M, Matsugi J, Furukawa Y, Ohtsuki M, Yamauchi J, Yanagisawa K
    • Journal Title

      Sci Rep.

      Volume: 11(1) Issue: 1 Pages: 20658-20658

    • DOI

      10.1038/s41598-021-00200-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07035, KAKENHI-PROJECT-20K08661
  • [Journal Article] High-Throughput RNA Sequencing Reveals the Effect of NB-UVB Phototherapy on Major Inflammatory Molecules of Lesional Psoriasis2021

    • Author(s)
      Vacharanukrauh Pinyadapat、Meephansan Jitlada、Tangtanatakul Pattarin、Soonthornchai Wipasiri、Wongpiyabovorn Jongkonnee、Serirat Onsiri、Komine Mayumi
    • Journal Title

      Psoriasis: Targets and Therapy

      Volume: Volume 11 Pages: 133-149

    • DOI

      10.2147/ptt.s335913

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08661
  • [Journal Article] STAT3 Activation in Psoriasis and Cancers2021

    • Author(s)
      Kishimoto Megumi、Komine Mayumi、Sashikawa-Kimura Miho、Ansary Tuba Musarrat、Kamiya Koji、Sugai Junichi、Mieno Makiko、Kawata Hirotoshi、Sekimoto Ryutaro、Fukushima Noriyoshi、Ohtsuki Mamitaro
    • Journal Title

      Diagnostics

      Volume: 11 Issue: 10 Pages: 1903-1903

    • DOI

      10.3390/diagnostics11101903

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08661
  • [Journal Article] Population pharmacokinetic and exposure?response analysis of apremilast in Japanese subjects with moderate to severe psoriasis2021

    • Author(s)
      Okubo Yukari、Ohtsuki Mamitaro、Komine Mayumi、Imafuku Shinichi、Kassir Nastya、Petric Rosemary、Nemoto Osamu
    • Journal Title

      The Journal of Dermatology

      Volume: 48 Issue: 11 Pages: 1652-1664

    • DOI

      10.1111/1346-8138.16068

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08661
  • [Journal Article] Single‐center survey of biologic use for inflammatory skin diseases during the coronavirus disease 2019 pandemic2021

    • Author(s)
      Kado Soichiro、Kamiya Koji、Kishimoto Megumi、Maekawa Takeo、Kuwahara Aya、Sugai Junichi、Komine Mayumi、Ohtsuki Mamitaro
    • Journal Title

      The Journal of Dermatology

      Volume: 48 Issue: 12 Pages: 1907-1912

    • DOI

      10.1111/1346-8138.16159

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K08661
  • [Journal Article] Biologics for Psoriasis during the COVID-19 Pandemic2021

    • Author(s)
      Kamiya Koji、Komine Mayumi、Ohtsuki Mamitaro
    • Journal Title

      Journal of Clinical Medicine

      Volume: 10 Issue: 7 Pages: 1390-1390

    • DOI

      10.3390/jcm10071390

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K08661
  • [Journal Article] Calcipotriol induces the production of CTACK/CCL27, one of the potential suppressive factors in psoriasis inflammation2021

    • Author(s)
      Karakawa Masaru、Kishimoto Megumi、Ohtsuki Mamitaro、Komine Mayumi
    • Journal Title

      The Journal of Dermatology

      Volume: 48 Issue: 12 Pages: 1949-1950

    • DOI

      10.1111/1346-8138.16152

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K08661
  • [Journal Article] Novel missense mutation c.539A>G; p.Glu180Gly in keratin 1 causing epidermolytic ichthyosis2021

    • Author(s)
      Sashikawa Miho、Tsuda Hidetoshi、Komine Mayumi、Ohtsuki Mamitaro
    • Journal Title

      The Journal of Dermatology

      Volume: 48 Issue: 12 Pages: 0-0

    • DOI

      10.1111/1346-8138.16142

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08661, KAKENHI-PROJECT-20K08678, KAKENHI-PROJECT-20K17358
  • [Journal Article] Diversified Stimuli-Induced Inflammatory Pathways Cause Skin Pigmentation2021

    • Author(s)
      Hossain Md Razib、Ansary Tuba M.、Komine Mayumi、Ohtsuki Mamitaro
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 22 Issue: 8 Pages: 3970-3970

    • DOI

      10.3390/ijms22083970

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08661
  • [Journal Article] 核内に存在するサイトカイン2021

    • Author(s)
      小宮根真弓、金 美娟、大塩智之、唐川 大、岸本恵美、津田英利、富永眞一、大槻マミ太郎
    • Journal Title

      アレルギーの臨床

      Volume: 41 Pages: 1078-1081

    • Data Source
      KAKENHI-PROJECT-20K08661
  • [Journal Article] Inflammatory Molecules Associated with Ultraviolet Radiation-Mediated Skin Aging2021

    • Author(s)
      Ansary Tuba M.、Hossain Md. Razib、Kamiya Koji、Komine Mayumi、Ohtsuki Mamitaro
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 22 Issue: 8 Pages: 3974-3974

    • DOI

      10.3390/ijms22083974

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08661, KAKENHI-PROJECT-20K17325
  • [Journal Article] アトピー性皮膚炎とヘパラナーゼ2020

    • Author(s)
      小宮根真弓、東 伸昭、鈴木沙奈、川並史也、宮川尚子
    • Journal Title

      アレルギーの臨床

      Volume: 40 Pages: 515-518

    • Data Source
      KAKENHI-PROJECT-19K07091
  • [Journal Article] Differential expression of alarmins: IL-33 as a candidate marker for early diagnosis of toxic epidermal necrolysis.2018

    • Author(s)
      Adachi A., Komine M., Tsuda H., Nakajima S., Kabashima K., Ohtsuki M.
    • Journal Title

      J Allergy Clin Immunol Pract.

      Volume: 7 Issue: 1 Pages: 325-327

    • DOI

      10.1016/j.jaip.2018.05.037

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10135, KAKENHI-PROJECT-16K10172
  • [Journal Article] Methotrexate, but not narrowband ultraviolet B radiation, suppresses interleukin-33 mRNA levels in psoriatic plaques and protein levels in serum of patients with psoriasis2018

    • Author(s)
      Meephansan Jitlada、Subpayasarn Urairack、Ponnikorn Saranyoo、Chakkavittumrong Panlop、Juntongjin Premjit、Komine Mayumi、Ohtsuki Mamitaro、Poovorawan Yong
    • Journal Title

      The Journal of Dermatology

      Volume: 45 Issue: 3 Pages: 322-325

    • DOI

      10.1111/1346-8138.14009

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10172
  • [Journal Article] Real-world use of apremilast for patients with psoriasis in Japan2018

    • Author(s)
      Kishimoto Megumi、Komine Mayumi、Hioki Tomoyuki、Kamiya Koji、Sugai Junichi、Ohtsuki Mamitaro
    • Journal Title

      The Journal of Dermatology

      Volume: 45 Issue: 11 Pages: 1345-1348

    • DOI

      10.1111/1346-8138.14617

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10172
  • [Journal Article] Interleukin-33 is expressed in the lesional epidermis in herpes virus infection but not in verruca vulgaris.2018

    • Author(s)
      Jin M., Komine M., Tsuda H., Oshio T., Ohtsuki M.
    • Journal Title

      J Dermatol

      Volume: 45 Issue: 7 Pages: 855-857

    • DOI

      10.1111/1346-8138.14334

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10135, KAKENHI-PROJECT-16K10172
  • [Journal Article] Identification of promoter region of human IL-33 responsive to induction by IFNγ2017

    • Author(s)
      Tsuda H., Komine M., Tominaga S., Ohtsuki M.
    • Journal Title

      J Dermatol Sci

      Volume: 85 Issue: 2 Pages: 137-140

    • DOI

      10.1016/j.jdermsci.2016.11.002

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-16K10135, KAKENHI-PROJECT-16K10172
  • [Journal Article] Nuclear ezpression of IL-33 in epidermal keratinocytes promotes wound healing in mice2017

    • Author(s)
      Oshio T., Komine M., Tsuda H., Tominaga S., Saito H., Nakae S., Ohtsuki M.
    • Journal Title

      J Dermatol Sci

      Volume: 85 Issue: 2 Pages: 106-114

    • DOI

      10.1016/j.jdermsci.2016.10.008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10135, KAKENHI-PROJECT-16K10172
  • [Journal Article] Adalimumab administration after infliximab therapy is a successful treatment strategy for generalized pustular psoriasis.2017

    • Author(s)
      Matsumoto A, Komine M, Karakawa M, Kishimoto M, Ohtsuki M.
    • Journal Title

      Journal of Dermatology

      Volume: - Issue: 2 Pages: 202-204

    • DOI

      10.1111/1346-8138.13632

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10172
  • [Journal Article] Apremilast, an oral phosphodiesterase 4 inhibitor, in the treatment of Japanese patients with moderate to severe plaque psoriasis: Efficacy, safety and tolerability results from a phase 2b randomized controlled trial.2017

    • Author(s)
      Ohtsuki M, Okubo Y, Komine M, Imafuku S, Day RM, Chen P, Petric R, Maroli A, Nemoto O.
    • Journal Title

      Journal of Dermatology

      Volume: 44 Issue: 8 Pages: 873884-873884

    • DOI

      10.1111/1346-8138.13829

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10172
  • [Journal Article] Involvement of M2 macrophages in the pathomechanisms of multicentric reticulohistiocytosis.2017

    • Author(s)
      Kamiya K, Komine M, Murata S, Ohtsuki M.
    • Journal Title

      Journal of Dermatology

      Volume: 56 Issue: 8

    • DOI

      10.1111/ijd.13661

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10172
  • [Journal Article] Diagnosis of pseudoxanthoma elasticum in a 4-year-old boy2017

    • Author(s)
      Maki N., Komine M., Tsuda H., Fujita Y., Fujita E., Murata S., Demitsu T., Utani A., Ohtsuki M.
    • Journal Title

      J Dertmatol

      Volume: 印刷中 Issue: 2 Pages: 244-236

    • DOI

      10.1111/1346-8138.13805

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10135, KAKENHI-PROJECT-16K10172
  • [Journal Article] Effects of maxacalcitol ointment on skin lesions in patients with psoriasis receiving treatment with adalimumab.2016

    • Author(s)
      Karakawa M, Komine M, Kishimoto M, Maki N, Matsumoto A, Sugai J, Ohtsuki M
    • Journal Title

      Journal of Dermatology

      Volume: 43 Issue: 11 Pages: 1354-1357

    • DOI

      10.1111/1346-8138.13515

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10172
  • [Journal Article] Possible involvement of SDF-1/CXCL12 in the pathogenesis of Degos disease2013

    • Author(s)
      Meephansan J, Komine M, Hosoda S, Tsuda H, Karakawa M, Murata S, Demitsu T, Ohtsuki M
    • Journal Title

      J Am Acad Dermatol

      Volume: 68(1) Pages: 138-43

    • Data Source
      KAKENHI-PROJECT-23591652
  • [Journal Article] Peritoneal loose body: A case report and comparison with encapsulated fat necrosis.2013

    • Author(s)
      Maekawa T, Komine M, Murata S, Ohtsuki M.
    • Journal Title

      J Dermatol

      Volume: 40 Issue: 12 Pages: 1058-1058

    • DOI

      10.1111/1346-8138.12336

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591652
  • [Journal Article] Expression of IL-33 in the epidermis: The mechanism of induction by IL-17.2013

    • Author(s)
      Meephansan J, Komine M, Tsuda H, Karakawa M, Tominaga S, Ohtsuki M.
    • Journal Title

      J Dermatol Sci

      Volume: 71 Issue: 2 Pages: 107114-107114

    • DOI

      10.1016/j.jdermsci.2013.04.014

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591652, KAKENHI-PROJECT-25461709
  • [Journal Article] Pustular eruption induced by sorafenib in a case of psoriasis vulgaris.2013

    • Author(s)
      Maki N, Komine M, Takatsuka Y, Maekawa T, Murata S, Ohtsuki M.
    • Journal Title

      J Dermatol

      Volume: 40 Issue: 4 Pages: 299-299

    • DOI

      10.1111/1346-8138.12097

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591652
  • [Journal Article] Expression of IL-33 in the epidermis: The mechanism of induction by IL-172013

    • Author(s)
      Meephansan J, Komine M, Tsuda M, Karakawa M, Tominaga S, Ohtsuki M
    • Journal Title

      J Dermatol Sci

      Volume: 未定

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591652
  • [Journal Article] Case of pemphigoid involving skin and mucous membrane with immunoglobulin G autoantibodies targeted to BP180 and laminin-332.2013

    • Author(s)
      Hosoda S, Suzuki M, Komine M, Fujita E, Yamada T, Murata S, Koga H, Hashimoto T, Ohtsuki M.
    • Journal Title

      J Dermatol

      Volume: 40 Issue: 12 Pages: 10671068-10671068

    • DOI

      10.1111/1346-8138.12311

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591652
  • [Journal Article] Ultraviolet B irradiation induces the expression of IL-33 mRNA and protein in normal human epidermal keratinocytes2012

    • Author(s)
      Meephansan J, Komine M, Tsuda H, Tominaga S, Ohtsuki M
    • Journal Title

      J Dermatol Sci

      Volume: 65(1) Pages: 72-4

    • Data Source
      KAKENHI-PROJECT-23591652
  • [Journal Article] Novel splice variants of IL-33: differential expression in normal and transformed cells2012

    • Author(s)
      Tsuda H, Komine M, Karakawa M, Etoh T, Tominaga S, Ohtsuki M
    • Journal Title

      J Invest Dermatol

      Volume: 132(11) Pages: 2661-4

    • Data Source
      KAKENHI-PROJECT-23591652
  • [Journal Article] Ultraviolet B irradiation induces the production of IL-33 in normal human epidermal keratinocytes2012

    • Author(s)
      Meephansan J, Komine M, Tsuda H, Tominaga S, Ohtsuki M.
    • Journal Title

      Journal of Dermatological Science

      Volume: 65 Pages: 71-74

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591652
  • [Journal Article] Regulation of IL-33 expression by interferon-γ and tumor necrosis factor-α in normal human epidermal keratinocytes2012

    • Author(s)
      Meephansan J, Tsuda H, Komine M, Etoh T, Tominaga S, Ohtsuki M.
    • Journal Title

      Journal of Investigative Dermatology

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591652
  • [Journal Article] Novel splice variants of IL-33; differential expression in normal and transformed cells2012

    • Author(s)
      Tsuda H, Komine M, Karakawa M, Tominaga S, Ohtsuki M.
    • Journal Title

      Journal of Investigative Dermatology

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591652
  • [Journal Article] 表皮角化細胞におけるIL-33産生機序について2012

    • Author(s)
      ジトラダミーファンサン、小宮根真弓、津田英利、富永眞一、大槻マミ太郎
    • Journal Title

      医薬の門

    • Data Source
      KAKENHI-PROJECT-23591652
  • [Journal Article] Regulation of IL-33 expression by IFN-γand tumor necrosis factor-αin normal human epidermal keratinocytes2012

    • Author(s)
      Meephansan J, Tsuda H, Komine M, Tominaga S, Ohtsuki M
    • Journal Title

      J Invest Dermatol

      Volume: 132(11) Pages: 2593-600

    • Data Source
      KAKENHI-PROJECT-23591652
  • [Journal Article] The levels of soluble ST2 in sera and bullous fluid from patients with bullous pemphigoid2012

    • Author(s)
      Wakatabi K, Komine M, Meephansan J, Matsuyama Y, Tsuda H, Tominaga S, Ohtsuki M
    • Journal Title

      Eur J Dermatol

      Volume: 22(3) Pages: 333-6

    • Data Source
      KAKENHI-PROJECT-23591652
  • [Journal Article] Ultraviolet B irradiation induces the expression of IL-33 mRNA and protein in normal human epidermal keratinocytes2012

    • Author(s)
      Meephansan, J., Komine, M., Tsuda, H., Tominaga, S., and Ohtsuki, M.
    • Journal Title

      J. Dermatol. Sci

      Volume: 65 Issue: 1 Pages: 72-74

    • DOI

      10.1016/j.jdermsci.2011.10.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590289
  • [Journal Article] Sustained elevation of interleukin-33 in sera and synovial fluids from patients with rheumatoid arthritis non-responsive to anti-tumor necrosis factor : possible association with persistent IL-1βsignaling and a poor clinical response2012

    • Author(s)
      Matsuyama Y, Okazaki H, Hoshino M, Onishi S, Kamata Y, Nagatani K, Nagashima T, Iwamoto M, Yoshio T, Ohto-Ozaki H, Tamemoto H, Komine M, Sekiya H, Tominaga S, Minota S
    • Journal Title

      Rheumatol Int

      Volume: 32(5) Pages: 1397-401

    • Data Source
      KAKENHI-PROJECT-23591652
  • [Journal Article] Suppressive effect of calcipotriol on the induction of matrix metalloproteinase (MMP)-9 and MMP-13 in a human squamous cell carcinoma cell line2012

    • Author(s)
      Meephansan J, Komine M, Tsuda H, Ohtsuki M
    • Journal Title

      Clin Exp Dermatol

      Volume: 37(8) Pages: 889-96

    • Data Source
      KAKENHI-PROJECT-23591652
  • [Journal Article] Regulation of IL-33 expression by IFN-γ and tumor necrosis factor-α in normal human epidermal keratinocytes.2012

    • Author(s)
      Meephansan, J., Tsuda, H., Komine, M., Tominaga, S., and Ohtsuki, M
    • Journal Title

      J. Invest. Dermatol

      Volume: 132 Issue: 11 Pages: 2593-2600

    • DOI

      10.1038/jid.2012.185

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590289, KAKENHI-PROJECT-23591652
  • [Journal Article] Sustained elevation of interleukin-33 in sera and synovial fluids from patients with rheumatoid arthritis non-responsive to anti-tumor necrosis factor: possible association with persistent IL-1βsignaling and a poor clinical response2012

    • Author(s)
      Matsuyama, Y., Okazaki, H., Hoshino, M., Onishi, S., Kamata, Y., Nagatani, K., Nagashima, T., Iwamoto, M., Yoshio, T., Ohto-Ozaki, H., Tamemoto, H., Komine, M.,Sekiya, H., Tominaga, S. and Minota, S.
    • Journal Title

      Rheumatol. Int

      Volume: 32 Issue: 5 Pages: 1397-1401

    • DOI

      10.1007/s00296-011-1854-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590289
  • [Journal Article] The levels of soluble ST2 in sera and bullous fluid from patients with bullous pemphigoid.2012

    • Author(s)
      Wakatabi, K., Komine, M., Meephansan, J., Matsuyama, Y., Tsuda, H., Tominaga, S., and Ohtsuki, M.
    • Journal Title

      Eur. J. Dermatol

      Volume: 22 Issue: 3 Pages: 333-336

    • DOI

      10.1684/ejd.2012.1706

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590289, KAKENHI-PROJECT-23591652
  • [Journal Article] Novel splice variants of IL-33: Differential expression in normal and transformed cells2012

    • Author(s)
      Tsuda, H., Komine, M., Karakawa, M., Etoh, T., Tominaga, S., and Ohtsuki, M
    • Journal Title

      J. Invest. Dermatol

      Volume: 132 Issue: 11 Pages: 2661-2664

    • DOI

      10.1038/jid.2012.180

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590289, KAKENHI-PROJECT-23591652
  • [Journal Article] Anti-cyclic citrullinated peptide antibodies and IL-23p19 in psoriatic arthritis.2009

    • Author(s)
      Shibata S, Tada Y, Komine M, Hattori N, Osame S, Kanda N, Watanabe S, Saeki H, Tamaki K.
    • Journal Title

      J Dermatol Sci. 53(1)

      Pages: 34-9

    • NAID

      10025331942

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] Erythroderma associated with leukocytosis in premalignant myeloproliferative disorder.2009

    • Author(s)
      Takatsuka Y, Komine M, Fujita E, Koike Y, Yamada T, Murata S, Ohtsuki M.
    • Journal Title

      Int J Dermatol. 48(3)

      Pages: 324-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] Pyoderma gangrenosum associated with Takayasu's arteritis without typical symptoms.2009

    • Author(s)
      Futaki K, Komine M, Hosoda S, Hirashima M, Yokokura H, Yamada T, Murata S, Matsuyama Y, Nagashima T, Nara H, Minota S, Ohtsuki M.
    • Journal Title

      Eur J Dermatol. 19(3)

      Pages: 266-267

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] Erythroderma associated with leukocytosis in premalignant myeloproliferative disorder.2009

    • Author(s)
      Takatsuka Y, Komine M, et al.
    • Journal Title

      Int J Dermatol. 48(3)

      Pages: 324-326

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] Serum high molecular weight adiponectin levels are decreased in psoriasis patients.2009

    • Author(s)
      Shibata S, Saeki H, Tada Y, Karakawa M, Komine M, Tamaki K.
    • Journal Title

      J Dermatol Sci.

    • NAID

      10025334308

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] Pyoderma gangrenosum associated with Takayasu's arteritis without typical symptoms.2009

    • Author(s)
      Futaki K, Komine M, et al.
    • Journal Title

      Eur J Dermatol. 19(3)

      Pages: 266-267

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] Proliferating tricholemmal cystic carcinoma: a case containing differentiated and dedifferentiated parts.2008

    • Author(s)
      Masui Y, Komine M, Kadono T, Ishiura N, Maekawa T, Ihn H, Kikuchi K, Tamaki K.
    • Journal Title

      J Cutan Pathol. 35 Suppl 1

      Pages: 55-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] CCL27-transgenic mice show enhanced contact hypersensitivity to Th2, but not Th1 stimuli2008

    • Author(s)
      Kagami S, Saeki H, Tsunemi Y, Nakamura K, Kuwano Y, Komine M, Nakayama T, Yoshie O, Tamaki K
    • Journal Title

      Eur J Immunol 38巻

      Pages: 647-657

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209039
  • [Journal Article] CCL27-transgenic mice show enhanced contact hypersensitivity to Th2, but not Th1 stimuli.2008

    • Author(s)
      Kagami S, Saeki H, Tsunemi Y, Nakamura K, Kuwano Y, Komine M, Nakayama T, Yoshie O, Tamaki K.
    • Journal Title

      Eur J Immunol. 38(3)

      Pages: 647-57

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] CCR4 and CCR10 are expressed on epidermal keratinocytes and are involved in cutaneous immune reaction.2008

    • Author(s)
      Fujimoto S, Uratsuji H, Saeki H, Kagami S, Tsunemi Y, Komine M, Tamaki K.
    • Journal Title

      Cytokine. 44(1)

      Pages: 172-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] CCL27 transgenic mice show enhanced contact hypersensitivity to Th2,but not Th1 stimuli2008

    • Author(s)
      Kagami S, Saeki H, Tsunemi Y, Nakamura K, Kuwano Y, Komine M, Nakayama T, Yoshie O, Tamaki K.
    • Journal Title

      Eur J Immunol 38

      Pages: 647-657

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] Juvenile pustular psoriasis associated with steroid withdrawal syndrome due to topical corticosteroid.2008

    • Author(s)
      Saeki H, Watanabe A, Tada Y, Kakinuma T, Komine M, Ihn H, Asahina A, Etoh T, Kitanaka S, Sato U, Kano H, Igarashi T, Tamaki K.
    • Journal Title

      J Dermatol. 35(9)

      Pages: 601-3

    • NAID

      10024298051

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] Serum 5-S-cysteinyldopa levels in patients with psoriasis undergoing narrowband ultraviolet B phototherapy.2008

    • Author(s)
      Kikuchi K, Wakamatsu K, Tada Y, Komine M, Ito S, Tamaki K.
    • Journal Title

      Clin Exp Dermatol. 33(6)

      Pages: 750-3

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] Six novel mutations of the ADAR1 gene in patients with dyschromatosis symmetrica hereditaria: histological observation and comparison of genotypes and clinical phenotypes.2008

    • Author(s)
      Kondo T, Suzuki T, Mitsuhashi Y, Ito S, Kono M, Komine M, Akita H, Tomita Y.
    • Journal Title

      J Dermatol. 35(7)

      Pages: 395-406

    • NAID

      10024297257

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] CCR4 and CCR10 are expressed on epidermal keratinocytes and are involved in cutaneous immune reaction.2008

    • Author(s)
      Fujimoto S, Uratsuji H, Saeki H, Kagami S, Tsunemi Y, Komine M, Tamaki K.
    • Journal Title

      Cytokine 44(1)

      Pages: 172-178

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] ケラチノサイトの生物学:ストレスとケラチノサイト2007

    • Author(s)
      小宮根 真弓
    • Journal Title

      日本皮膚科学会雑誌 117

      Pages: 2420-2421

    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] The direct action of lalpha,25(OH)2-vitamin D3 on purified mouse Langerhans cells.Cell Immunol.2007Feb;245(2):70-9.Epub 2007 May 152007

    • Author(s)
      Fujita H, Qeahina A, Komine M, Tamaki K
    • Journal Title

      Cell Immunol 245

      Pages: 70-79

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] Early inflammatory changes in the "perilesional skin" of psoriatic plaques: is there interaction between dendritic cells and keratinocytes?2007

    • Author(s)
      Komine M, Karakawa M, Takekoshi T, Sakurai N, Minatani Y, Mitsui H, Tada Y, Saeki H, Asahina A, Tamaki K.
    • Journal Title

      J Invest Dermatol. 127(8)

      Pages: 1915-22

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] The direct action of 1alpha,25(OH)2-vitamin D3 on purified mouse Langerhans cells.2007

    • Author(s)
      Fujita H, Asahina A, Komine M, Tamaki K.
    • Journal Title

      Cell Immunol. 245(2)

      Pages: 70-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] 乾癬の臨床評価におけるSelf Administered PASIの有用性とQOL指標との関連性2007

    • Author(s)
      福地 修, 太田 有史, 石地 尚興, 本田 まりこ, 上出 良一, 中川 秀己, 小宮根 真弓, 長谷川 友紀
    • Journal Title

      日本皮膚科学会雑誌 117

      Pages: 1969-1976

    • NAID

      10021305042

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] The involvement of Gab1 PI 3-kinase in betal integrin signaling in keratinocytes2007

    • Author(s)
      Kuwano Y, Fujimoto M, Watanabe R, Ishiura N, NakashimaH, Komine M, Hamazaki TS, Tamaki K, Okochi H.
    • Journal Title

      Biochem Biophys Res Commun 361

      Pages: 224-229

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] Psoriasis vulgaris associated with superior vena cava syndrome due to lung cancer metastasis.2007

    • Author(s)
      Saeki H, Hosono S, Tsunemi Y, Sasaki K, Kadono T, Ihn H, Komine M, Asahina A, Kikuchi K, Tamaki K.
    • Journal Title

      J Dermatol. 34(5)

      Pages: 356-9

    • NAID

      10020116037

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] CCL17 transgenic mice show an enhanced Th2-type response to both allergic and non-allergic stimuli2007

    • Author(s)
      Tsunemi Y, Saeki H, Nakamura K, Nagakubo D, Nakayama T, Yoshie O, Kagami S, Shimazu K, Kadono T, Sugaya M, Komine M, Matsushima K, Tamaki K
    • Journal Title

      Eur J Immunol 36巻

      Pages: 2116-2127

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209039
  • [Journal Article] Serum uric acid levels in patients with vitiligo receiving narrowband ultraviolet B phototherapy. Clin Exp Dermatol. 2007 Jan;32(1):107-82007

    • Author(s)
      Kikuchi K, Komine M, Takekoshi T, Tamales K.
    • Journal Title

      Clip Exp Dermatol 32

      Pages: 107-108

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] Sezary syndrome treated with narrowband ultraviolet B: time-course measurement of serum levels of CCL17/CCL27.2007

    • Author(s)
      Masui Y, Sugaya M, Kagami S, Fujita H, Yano S, Nagao M, Komine M, Saeki H, Ihn H, Kikuchi K, Tamaki K.
    • Journal Title

      Clin Exp Dermatol. 32(1)

      Pages: 57-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] 以前から使われている薬剤の新しい使い方・問題点 マクロライド系抗生物質2007

    • Author(s)
      小宮根 真弓
    • Journal Title

      膚科の臨床 49

      Pages: 1227-1230

    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] Serum uric acid levels in patients with vitiligo receiving narrowband ultraviolet B phototherapy.2007

    • Author(s)
      Kikuchi K, Komine M, Takekoshi T, Tamaki K.
    • Journal Title

      Clin Exp Dermatol. 32(1)

      Pages: 107-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] イトラコナゾール400mgパルス療法開始後肝胆道系酵素値上昇頻度の検討 パルス療法開始前肝胆道系酵素値異常の有無による比較2007

    • Author(s)
      常深祐一郎, 嶋津苗胤, 服部尚子, 白井明, 佐伯秀久, 小宮根真弓, 玉置邦彦
    • Journal Title

      皮膚科の臨床 49(1)

      Pages: 45-47

    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] Serum uric acid levels in patients with vitiligo receiving narrowband ultraviolet B phototherapy.2007

    • Author(s)
      Kikuchi K, Komine M, Takekoshi T, et al.
    • Journal Title

      Clinical and Experimental Dermatology 32(1)

      Pages: 107-108

    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] A case of milia en plaque successfully treated with oral etretinate.2007

    • Author(s)
      Ishiura N, Komine M, Kadono T, Kikuchi K, Tamaki K.
    • Journal Title

      Br J Dermatol. 157(6)

      Pages: 1287-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] Early inflammatory changes in the "perilesional skin"of psoriatic plaques:is there interaction between dendritic cells and keratinocytes J Invest Dermatol.2007Aug;127(8):1915-22.Epub 2007 Apr 192007

    • Author(s)
      Komine M, Karakawa M, Takekoshi T, Sakurai N, Minatani Y, Mitsui H, Tada Y, Saeki H, Asahina A, Tamaki K
    • Journal Title

      J Invest Dermatol 127

      Pages: 1915-1922

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] 全身にみられる皮疹 内臓悪性腫瘍に伴う皮膚痴患 診断と治療95(9):1530-1536、 20072007

    • Author(s)
      小宮根 真弓
    • Journal Title

      診断と治療 95

      Pages: 1530-1536

    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] Sezaiy syndrome treated with narrowband uhavidet B:time-course measurement of serum levels of CCL17/CCL27. Clin Exp DermatoL2007 Jan;32(1):57-92007

    • Author(s)
      Masui Y, Sugaya M, KagamiS, Fujita H, Yano S, Nagao M, Komine M, Saeki H, Ihn H, Kikuchi, Tanmaki K.
    • Journal Title

      Clip Exp Dermatol 32

      Pages: 57-59

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] ERK inhibitor PD98059 promotes the phenotypic and functionalmaturation of murine resident Langerhans cells2007

    • Author(s)
      Fujita H, Asahina A, KomineM, Tamaki K.
    • Journal Title

      J Deramtol 34

      Pages: 403-406

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] The direct action of 1alpha,25(OH)2-vitamin D3 on purified mouse Langerhans cells2007

    • Author(s)
      Fujita H, Asahina A, Komine M, Tamaki K.
    • Journal Title

      Cell Immunol 245巻

      Pages: 70-79

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209039
  • [Journal Article] ERK inhibitor PD98059 promotes the phenotypic and functional maturation of murine resident Langerhans cells.2007

    • Author(s)
      Fujita H, Asahina A, Komine M, Tamaki K.
    • Journal Title

      J Dermatol. 34(6)

      Pages: 403-6

    • NAID

      10020115665

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] Early inflammatory changes in the "perilesional skin" of psoriatic plaques : is there interaction between dendritic cells and keratinocytes2007

    • Author(s)
      Komine M, Karakawa M, Takekoshi T, Sakurai N, Minatani Y, Mitsui H, Tada Y, Saeki H, Asahina A, Tamaki K.
    • Journal Title

      J Invest Dermatol 127巻

      Pages: 1915-1922

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209039
  • [Journal Article] 臨床研究から痒みに迫る 乾癬はなぜ痒い2007

    • Author(s)
      小宮根 真弓
    • Journal Title

      Visual Dermatology 6

      Pages: 710-712

    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] A case of milia en plaque successfully treated with oral etretinate2007

    • Author(s)
      Ishiura N, Komine M, Kadono T, Kikuchi K, Tamaki K.
    • Journal Title

      Br J Dermatol 157

      Pages: 1287-1289

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] Psoriasis vulgaris associated with superior vena. cava syndrome due tolung cancer metastasis2007

    • Author(s)
      Saeki Hl, Hosono S, TsunemiY, Sasaki K, Kadono T, IhnH, Komine M, Asahina A, Kikruchi K, Tamaki K.
    • Journal Title

      J Deramtol 34

      Pages: 356-359

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] Sezary syndrome treated with narrowband ultraviolet B : time-course measurement of serum levels of CCL17/CCL27.2007

    • Author(s)
      Masui Y, Sugaya M, Kagami S, Fujita H, Yano S, Nagao M, Komine M, et al.
    • Journal Title

      Clinical and Experimental Dermatology 32(1)

      Pages: 57-59

    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] The involvement of Gab1 and PI 3-kinase in beta1 integrin signaling in keratinocytes.2007

    • Author(s)
      Kuwano Y, Fujimoto M, Watanabe R, Ishiura N, Nakashima H, Komine M, Hamazaki TS, Tamaki K, Okochi H.
    • Journal Title

      Biochem Biophys Res Commun. 361(1)

      Pages: 224-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] Early inflammatory changes in the "peri-lesional skin" of psoriatic plaques : Is there interaction between dendritic cells and karatinocytes?2007

    • Author(s)
      Komine M, Karakawa M., Takekoshi T, et al.
    • Journal Title

      Journal of Investigative Dermatology (In press)

    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] A novel keratin 9 gene mutation (Met156Arg) in a Japanese patient with epidermolytic palmoplantar keratoderma.2006

    • Author(s)
      Shimazu K, Tsunemi Y, Hattori N, Saeki H, Komine M, Adachi M, Tamaki K.
    • Journal Title

      Int J Dermatol. 45(9)

      Pages: 1128-30

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] Treatment of HIV-associated eosinophilic pustular folliculitis with narrow-band UVB.2006

    • Author(s)
      Kuwano Y, Watanabe R, Fujimoto M, Komine M, Asahina A, Tsukada N, Tamaki K.
    • Journal Title

      Int J Dermatol. 45(10)

      Pages: 1265-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] Necrolytic migratory erythema without glucagonoma in a patient with short bowel syndrome.2006

    • Author(s)
      Nakashima H, Komine M, Sasaki K, Mitsui H, Fujimoto M, Ihn H, Asahina A, Kikuchi K, Tamaki K.
    • Journal Title

      Journal of Dermatology 33(8)

      Pages: 557-562

    • NAID

      10020339737

    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] 趾爪白癬に対するイトラコナゾール400mgパルス療法の臨床効果の検討 60歳未満群と65歳以上群の比較2006

    • Author(s)
      常深祐一郎, 嶋津苗胤, 服部尚子, 白井明, 外山啓子, 佐伯秀久, 小宮根真弓, 玉置邦彦
    • Journal Title

      日本皮膚科学会雑誌 116(2)

      Pages: 193-200

    • NAID

      10019250345

    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] Treatment of psoriasis vulgaris with narrow-band UVB and topical Maxacalcitol.2006

    • Author(s)
      Takekoshi T, Asahina A, Komine M, Tamaki K.
    • Journal Title

      Acta Derm Venereol. 86(4)

      Pages: 375-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] Activation of Akt by mechanical stretching in human epidermal keratinocytes.2006

    • Author(s)
      Yano S, Komine M, Fujimoto M, Okoch H, Tamaki K.
    • Journal Title

      Experimental Dermatology 15(5)

      Pages: 356-361

    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] Novel mutation (Asp158Val) in H1 domain of keratin 5 gene in a Japanese patient with Kobner-type epidermolysis bullosa simplex.2006

    • Author(s)
      Saeki H, Nakamura K, Tsunemi Y, Komine M, Tamaki K.
    • Journal Title

      Journal of Dermatology 33(10)

      Pages: 692-695

    • NAID

      10020339213

    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] Activation of Akt by mechanical stretching in human epidermal keratinocytes.2006

    • Author(s)
      Yano S, Komine M, Fujimoto M, Okochi H, Tamaki K.
    • Journal Title

      Exp Dermatol. 15(5)

      Pages: 356-61

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] 知っておきたい検査とその読み方 : 血液生化学検査、ケトン体2006

    • Author(s)
      小宮根真弓
    • Journal Title

      皮膚科の臨床 48(10)

      Pages: 1241-1244

    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] Treatment of psoriasis vulgaris with narrow-band UVB and topical Maxacalcitol.2006

    • Author(s)
      Takekoshi T, Asahina A, Komine M, Tamaki K.
    • Journal Title

      Acta Dermato-Venereologica 86(4)

      Pages: 375-376

    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] 知っておきたい検査とその読み方 : 血液生化学検査 フェリチン2006

    • Author(s)
      小宮根真弓
    • Journal Title

      皮膚科の臨床 48(10)

      Pages: 1245-1246

    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] Novel mutation (Asp158Val) in H1 domain of keratin 5 gene in a Japanese patient with Kobner-type epidermolysis bullosa simplex.2006

    • Author(s)
      Saeki H, Nakamura K, Tsunemi Y, Komine M, Tamaki K.
    • Journal Title

      J Dermatol. 33(10)

      Pages: 692-5

    • NAID

      10020339213

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] A case of epidermolysis bullosa simplex with a newly found missense mutation and polymorphism in the highly conserved helix termination motif among type I keratins, which was previously reported as a pathogenic missense mutation.2006

    • Author(s)
      Hattori N, Komine M, Kaneko T, et al.
    • Journal Title

      British Journal of Dermatology 155(5)

      Pages: 1062-1063

    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] Interleukin 12 production by monocytes from patients with psoriasis and its inhibition by ciclosporin A.2006

    • Author(s)
      Tada Y, Asahina A, Takekoshi T, Kishimoto E, Mitsui H, Saeki H, Komine M, Tamaki K.
    • Journal Title

      Br J Dermatol. 154(6)

      Pages: 1180-3

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] Interleukin 12 production by monocytes from patients with psoriasis and its inhibition by ciclosporin A.2006

    • Author(s)
      Tada Y, Asahina A, Takekoshi T, Kishimoto E, Mitsui H, Saeki H, Komine M, Tamaki K.
    • Journal Title

      British Journal of Dermatology 154(6)

      Pages: 1180-1183

    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] CCL17 transgenic mice show an enhanced Th2-type response to both allergic and non-allergic stimuli.2006

    • Author(s)
      Tsunemi Y, Saeki H, Nakamura K, Nagakubo D, Nakayama T, Yoshie O, Kagami S, Shimazu K, Kadono T, Sugaya M, Komine M, Matsushima K, Tamaki K.
    • Journal Title

      Eur J Immunol. 36(8)

      Pages: 2116-27

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] Treatment of HIV-associated eosinophilic pustular folliculitis with narrow-band UVB.2006

    • Author(s)
      Kuwano Y, Watanabe R, Fujimoto M, Komine M, Asahina A, Tsukada N, Tamaki K.
    • Journal Title

      Internal Journal of Dermatology 45(1)

      Pages: 1265-1267

    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] A case of epidermolysis bullosa simplex with a newly found missense mutation and polymorphism in the highly conserved helix termination motif among type I keratins, which was previously reported as a pathogenic missense mutation.2006

    • Author(s)
      Hattori N, Komine M, Kaneko T, Shimazu K, Tsunemi Y, Koizumi M, Goto J, Hashimoto T.
    • Journal Title

      Br J Dermatol. 155(5)

      Pages: 1062-3

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] 乾癬特異的QOL指標Psoriasis Disability Index(PDI)日本語版の開発と信頼性・妥当性の検討2006

    • Author(s)
      福地修, FinalyAndrew Y., 太田有史, 石地尚興, 本田まりこ, 上出良一, 中川秀己, 小宮根真弓, 長谷川友紀
    • Journal Title

      日本皮膚科学会雑誌 116(11)

      Pages: 1583-1591

    • NAID

      10018388579

    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] CCL17 transgenic mice show an enhanced Th2-type response to both allergic and non-allergic stimuli.2006

    • Author(s)
      Tsunemi Y, Saeki H, Nakamura K, Nagakubo D, Nakayama T, Yoshie O, Kagami S, Shimazu K, Kadono T, Sugaya M, Komine M, Matsushima K, Tamaki K.
    • Journal Title

      European Journal of Immunology 36(8)

      Pages: 2116-2127

    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] 14員環マクロライドの抗炎症作用とその機序2006

    • Author(s)
      小宮根真弓
    • Journal Title

      アレルギー科 21(4)

      Pages: 347-354

    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] 皮膚病変に見る消化器疾患、壊疽性膿皮症2006

    • Author(s)
      冨田学, 佐伯秀久, 小宮根真弓
    • Journal Title

      G. I. Research 14(3)

      Pages: 72-76

    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] Necrolytic migratory erythema without glucagonoma in a patient with short bowel syndrome.2006

    • Author(s)
      Nakashima H, Komine M, Sasaki K, Mitsui H, Fujimoto M, Ihn H, Asahina A, Kikuchi K, Tamaki K.
    • Journal Title

      J Dermatol. 33(8)

      Pages: 557-62

    • NAID

      10020339737

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] CCL28 production in HaCaT cells was mediated by different signal pathways from CCL27.2006

    • Author(s)
      Kagami S, Saeki H, Komine M, Kakinuma T, Nakamura K, Tsunemi Y, Sasaki K, Asahina A, Tamaki K.
    • Journal Title

      Experimental Dermatology 15(2)

      Pages: 95-100

    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] A novel karatin 9 gene mutation (Melt156Arg) in a Japanese patient with epidermolytic palmoplantar keratoderma.2006

    • Author(s)
      Shimazu K, Tsunemi Y, Hattori N, Saeki H, Komine M, Adachi M, Tamaki K.
    • Journal Title

      International Journal of Dermatology 45(9)

      Pages: 1128-1130

    • Data Source
      KAKENHI-PROJECT-18591236
  • [Journal Article] Interleukin-4 and interleukin-13 enhance CCL26 production in a human keratinocyte cell line, HaCaT cells.2005

    • Author(s)
      Kagami S, Saeki H, Komine M, (omission), Asahina A, Tamaki K
    • Journal Title

      Clin Exp Immunol 141(3)

      Pages: 459-466

    • Data Source
      KAKENHI-PROJECT-17209039
  • [Journal Article] Mechanism of thymus- and activation-regulated chemokine (TARC)/CCL17 production and its modulation by roxithromycin.2005

    • Author(s)
      Komine M, (omission), Tamaki K
    • Journal Title

      J Invest Dermatol 125(3)

      Pages: 491-498

    • Data Source
      KAKENHI-PROJECT-17209039
  • [Journal Article] Mechanical stretching in vitro regulates signal transduction pathways and cellular proliferation in human epidermal keratinocytes.2004

    • Author(s)
      Yano S, Komine M, Fujimoto M, Okochi H, Tamaki K.
    • Journal Title

      J Invest Dermatol. 122(3)

      Pages: 783-790

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570800
  • [Journal Article] Mechanical stretching in vitro regulates signal transduction pathways and cellular proliferation in human epidermal keratinocytes2004

    • Author(s)
      Yano S, Komine M. et al.
    • Journal Title

      Journal of Investigative Dermatology 122(3)

      Pages: 783-790

    • Data Source
      KAKENHI-PROJECT-14570800
  • [Journal Article] Mechanical stretching in vitro regulates signal transduction pathways and cellular proliferation in human epidermal Keratinocytes.2004

    • Author(s)
      Yano S, Komine M, et al.
    • Journal Title

      Journal of Investigative Dermatology 122(3)

      Pages: 783-790

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14570800
  • [Journal Article] Interleukin 15 induces the signals of epidermal proliferation through ERK and PI 3-kinase in a human epidermal keratinocyte cell line, HaCaT.2003

    • Author(s)
      Yano S, Komine M, Fujimoto M, Okochi H, Tamaki K.
    • Journal Title

      Biochem Biophys Res Commun. 301(4)

      Pages: 841-847

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570800
  • [Journal Article] Interleukin 15 induces the signals of epidermal proliferation through ERK and PI3 kinase in a human epidermal Keratinocyte cell line, HaCaT.2003

    • Author(s)
      Yano S, Komine M, et al.
    • Journal Title

      Biochem Biophys Res Commun. 301(4)

      Pages: 841-847

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14570800
  • [Journal Article] Significant elevation of serum levels of eotaxin-3/CCL26, but not of eotaxin-2/CCL24, in patients with atopic dermatitis : serum eotaxin-3/CCL26 levels reflect the disease activity of atopic dermatitis.2003

    • Author(s)
      Kagami S, Kakinuma T, Saeki H, Tsunemi Y, Fujita H, Nakamura K, Takekoshi T, Kishimoto M, Mitsui H, Torii H, Komine M, Asahina A, Tamaki K.
    • Journal Title

      Clin Exp Immunol. 134(2)

      Pages: 309-313

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570800
  • [Journal Article] Interleukin 15 induces the signals of epidermal proliferation through ERK and PI 3 kinase in a human epidermal keratinocyte cell line, HaCaT.2003

    • Author(s)
      Yano S, Komine M, et al.
    • Journal Title

      Biochem Biophys Res Commun. 301(4)

      Pages: 841-847

    • Data Source
      KAKENHI-PROJECT-14570800
  • [Journal Article] Increased serum cutaneous T cell-attracting chemokine (CCL27) levels in patients with atopic dermatitis and psoriasis vulgaris.2003

    • Author(s)
      Kakinuma T, Saeki H, Tsunemi Y, Fujita H, Asano N, Mitsui H, Tada Y, Wakugawa M, Watanabe T, Torii H, Komine M, Asahina A, Nakamura K, Tamaki K.
    • Journal Title

      J Allergy Clin Immunol. 111(3)

      Pages: 592-597

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570800
  • [Journal Article] A strong supprassor of cell proliferation, induces up-regulation of Keratin K6, one of the Inflammatory and proliferation associated Keratins.2002

    • Author(s)
      Hattori N, Komine M, et al.
    • Journal Title

      Journal of Invesfigative Dermatology 119(2)

      Pages: 403-410

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14570800
  • [Journal Article] IL-4, but not IL-13, modulates TARC (thymus and activation-regulated chemokine)/CCL17 and IP-10 (interferon-induced protein of 10kDA)/CXCL10 release by TNF-alpha and IFN-gamma in HaCaT cell line.2002

    • Author(s)
      Kakinuma T, Nakamura K, Wakugawa M, Yano S, Saeki H, Torii H, Komine M, Asahina A, Tamaki K.
    • Journal Title

      Cytokine. 20(1)

      Pages: 1-6

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570800
  • [Journal Article] Interferon-□, A Strong Suppressor of Cell Proliferation, Induces Up-regulation of Keratin K6, One of The Inflammatory-and Proliferation-associated Keratins.2002

    • Author(s)
      Hattori N, Komine M, Kaneko T, Hashimoto K, Tamaki K.
    • Journal Title

      J Invest Dermatol. 119(2)

      Pages: 403-410

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570800
  • [Journal Article] Serum macrophage-derived chemokine (MDC) levels are closely related with the disease activity of atopic dermatitis.2002

    • Author(s)
      Kakinuma T, Nakamura K, Wakugawa M, Mitsui H, Tada Y, Saeki H, Torii H, Komine M, Asahina A, Tamaki K.
    • Journal Title

      Clin Exp Immunol. 127(2)

      Pages: 270-273

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570800
  • [Patent] 褥瘡治療剤、褥瘡治療方法、及び褥瘡予防方法2020

    • Inventor(s)
      小宮根
    • Industrial Property Rights Holder
      小宮根
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2020-119951
    • Filing Date
      2020
    • Data Source
      KAKENHI-PROJECT-20K08661
  • [Patent] 褥瘡治療剤、褥瘡治療方法、及び褥瘡予防方法2020

    • Inventor(s)
      小宮根 真弓
    • Industrial Property Rights Holder
      小宮根 真弓
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2020-119951
    • Filing Date
      2020
    • Data Source
      KAKENHI-PROJECT-20K08661
  • [Patent] 白斑治療外用薬2008

    • Inventor(s)
      玉置邦彦, 菊池かな子, 小宮根真弓, 藤本盛輝
    • Industrial Property Rights Holder
      東京大学
    • Industrial Property Number
      2008-097207
    • Filing Date
      2008
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Patent] 白斑治療外用薬2008

    • Inventor(s)
      玉置邦彦、菊池かな子、小宮根真弓、藤本盛輝
    • Industrial Property Rights Holder
      東京大学
    • Filing Date
      2008
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Presentation] アトピー性皮膚炎モデルマウスの皮膚におけるヘパラナーゼの発現2024

    • Author(s)
      東之薗 優輝、服部 萌、稲月 悠、田中 玲也、高橋 勝彦、中島 元夫、入村 達郎、小宮根 真弓、東 伸昭
    • Organizer
      日本薬学会第144年会
    • Data Source
      KAKENHI-PROJECT-22K06587
  • [Presentation] アトピー性皮膚炎皮疹部におけるヘパラナーゼの発現2023

    • Author(s)
      稲月 悠、服部 萌、谷田部 真衣、川並 史也、宮川 尚子、鈴木 沙奈、高橋 勝彦、中島 元夫、入村 達郎、小宮根 真弓、東 伸昭
    • Organizer
      日本薬学会第143年会
    • Data Source
      KAKENHI-PROJECT-19K07091
  • [Presentation] アトピー性皮膚炎皮疹部におけるヘパラナーゼの発現2023

    • Author(s)
      稲月 悠、服部 萌、谷田部 真衣、川並 史也、宮川 尚子、鈴木 沙奈、高橋 勝彦、中島 元夫、入村 達郎、小宮根 真弓、東 伸昭
    • Organizer
      日本薬学会第143年会
    • Data Source
      KAKENHI-PROJECT-22K06587
  • [Presentation] 皮膚科における遺伝子診断2022

    • Author(s)
      小宮根真弓、宮内ひとみ、指川‐木村未歩、大槻マミ太郎
    • Organizer
      第67回 日本人類遺伝学会
    • Data Source
      KAKENHI-PROJECT-20K08661
  • [Presentation] IL-33 deficiency increases filaggrin protein level with no impact on TEWL increase after tape-stripping2022

    • Author(s)
      Md Razib Hossain, Tuba M Ansary, Mayumi Komine, Mamitaro Ohtsuki
    • Organizer
      2022 Annual Meeting of European Society for Dermatological Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08661
  • [Presentation] Induction of type 17 collagen decreases ultraviolet b-induced cellular senescence in human htert/ker-ct keratinocyte2022

    • Author(s)
      Tuba M Ansary, Koji Kamiya, Md Razib Hossain, Mayumi Komine, Mamitaro Ohtsuki
    • Organizer
      2022 Annual Meeting of Society for Investigative Dermatology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08661
  • [Presentation] IL-33 is a negative regulator of filaggrin in the skin, but not in barrier homeostasis2022

    • Author(s)
      Md Razib Hossain, Tuba M Ansary, Mayumi Komine, Mamitaro Ohtsuki
    • Organizer
      2022 Annual Meeting of Society for Investigative Dermatology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08661
  • [Presentation] Induction of Type XVII collagen decreases cellular senescence in Human hTert/KER-CT keratinocytes2022

    • Author(s)
      Tuba M Ansary, Koji Kamiya, Md Razib Hossain, Mayumi Komine, Mamitaro Ohtsuki
    • Organizer
      2022 Annual Meeting of Japanese Society for Investigative Dermatology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08661
  • [Presentation] The protective effects of Apocynin against ultraviolet B-induced cellular senescence in human keratinocytes2022

    • Author(s)
      Tuba M Ansary, Koji Kamiya, Md Razib Hossain, Mayumi Komine, Mamitaro Ohtsuki
    • Organizer
      2022 Annual Meeting of European Society for Dermatological Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08661
  • [Presentation] Loss of IL-33 causes increased filaggrin protein level without impact on TEWL after tape-stripping2022

    • Author(s)
      Md Razib Hossain, Tuba M Ansary, Mayumi Komine, Mamitaro Ohtsuki
    • Organizer
      2022 Annual Meeting of Japanese Society for Investigative Dermatology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08661
  • [Presentation] Epidermolysis bullosa simplex with mottled pigmentationの親子例2021

    • Author(s)
      木村 未歩、小宮根真弓
    • Organizer
      第3回 日本白斑学会
    • Data Source
      KAKENHI-PROJECT-20K08661
  • [Presentation] Skin barrier function impairment in IL-33KO mice2021

    • Author(s)
      MD Razib Hossain, Tuba Ansary, Mayumi Komine, Mamitaro Ohtsuki
    • Organizer
      Japanese Society for Investigative dermatology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08661
  • [Presentation] IL-33 contributes to skin ulcer formation in ischemia-reperfusion-induced decubitus mouse model2021

    • Author(s)
      Jin Meijuan, Mayumi Komine, Mamitaro Ohtuski
    • Organizer
      Society for Investigative Dermatology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08661
  • [Presentation] Induction of Type XVII collagen decreases cellular senescence in Human hTert/KER-CT keratinocytes2021

    • Author(s)
      Tuba M. ANSARY1, MD Razib Hossain1, Mayumi Komine1, Mamitaro Ohtsuki1
    • Organizer
      Japanese Society for Investigative dermatology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08661
  • [Presentation] 褥瘡の病態におけるIL-33の役割及び治療への応用についての研究2021

    • Author(s)
      金 美娟、小宮根 真弓、大槻マミ太郎
    • Organizer
      日本炎症再生医学会
    • Data Source
      KAKENHI-PROJECT-20K08661
  • [Presentation] IL-33 deficiency protects skin from ulcer formation in ischemia-reperfusion-induced decubitus mouse model2021

    • Author(s)
      Jin Meijuan, Mayumi Komine, Mamitaro Ohtsuki
    • Organizer
      European Society for Dermatological Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08661
  • [Presentation] Effect of IL-33 on Ischemia-Reperfusion-induced decubitus mouse model2021

    • Author(s)
      Jin Meijyuan, Mayumi Komine, Mamitaro Ohtsuki
    • Organizer
      Japanese Society for Investigative Dermatology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08661
  • [Presentation] 長島型掌蹠角化症の2例2021

    • Author(s)
      木村 未歩、宮内ひとみ、小宮根真弓、大槻マミ太郎
    • Organizer
      角化症研究会
    • Data Source
      KAKENHI-PROJECT-20K08661
  • [Presentation] Effect of IL-33 on Ischemia-Reperfusion-induced decubitus mouse model2020

    • Author(s)
      Jin Meijyuan, Mayumi Komine, Mamitaro Ohtsuki
    • Organizer
      Japanese Society for Investigative Dermatology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08661
  • [Presentation] Poly I:CはTLR3-IRF3を介して IL-33をプロモーターレベルで誘導する2018

    • Author(s)
      小宮根真弓、金 美娟、津田英利、大槻マミ太郎
    • Organizer
      日本炎症・再生医学会
    • Data Source
      KAKENHI-PROJECT-16K10172
  • [Presentation] IL-33 determines the type of inflammation in psoriasis mice model2018

    • Author(s)
      Hidetoshi Tsuda, Mayumi Komine, Tomoyuki Hioki, Susumu Nakae, Mamitaro Ohtsuki
    • Organizer
      Inflammatory Skin Disease Summit
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10172
  • [Presentation] 表皮角化細胞へのTNFα刺激はIL-33の発現を抑制する2018

    • Author(s)
      津田英利、小宮根真弓、大槻マミ太郎
    • Organizer
      分子皮膚科フォーラム
    • Data Source
      KAKENHI-PROJECT-16K10172
  • [Presentation] 表皮細胞に対するアプレミラストの作用についての検討2018

    • Author(s)
      金 美娟、小宮根真弓、津田英利、大槻マミ太郎
    • Organizer
      山梨地方会
    • Data Source
      KAKENHI-PROJECT-16K10172
  • [Presentation] Loss of IL-33 alters cytokine profile in imiquimod-induced psoriasis model2017

    • Author(s)
      Tsuda H, Komine M, Ohtsuki M.
    • Organizer
      42nd Annual Meeting of Japanese Society for Investigative Dermatology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10172
  • [Presentation] STAT3 activation causes IL-33 expression in normal human epidermal keratinocyte2017

    • Author(s)
      Tsuda H, Komine M, Ohtsuki M.
    • Organizer
      47th Annual Meeting of European Society for Dermatological Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10172
  • [Presentation] The double-stranded RNA induces IL-33 promoter activation through TLR3-IRF3 pathway, depending on EGF receptor activation in normal human epidermal keratinocytes2017

    • Author(s)
      Jin M, Komine M, Tsuda H, Tominaga S, Ohtsuki M.
    • Organizer
      76th Annual Meeting of Society for Investigative Dermatology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10172
  • [Presentation] Nuclear IL-33 knock down by siRNA impairs cell division and cell motility of normal human epidermal keratinocytes2017

    • Author(s)
      Tsuda H, Komine M, Ohtsuki M.
    • Organizer
      76th Annual Meeting of Society for Investigative Dermatology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10172
  • [Presentation] Toll-like receptor 3 activation results in IL-33 promoter activation through IRF3 transcription factor depending on EGF receptor activation in normal human epidermal keratinocytes.2017

    • Author(s)
      Jin M, Komine M, Tsuda H, Ohtsuki M.
    • Organizer
      42nd Annual Meeting of Japanese Society for Investigative Dermatology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10172
  • [Presentation] Double-stranded RNA induces IL-33 expression through activation of EGFR, ERK, p38 and TBK-1 in normal epidermal keratinocytes.2016

    • Author(s)
      Meijuan Jin, Mayumi Komine, Hidetoshi Tsuda, Shin-ichi Tominaga, Mamitaro Ohtsuki
    • Organizer
      41th Annual Meeting of Japanese Society for Investigative Dermatology
    • Place of Presentation
      仙台国際センター、宮城県、仙台市
    • Year and Date
      2016-12-09
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10172
  • [Presentation] The loss of nuclear IL-33 affects cell division of normal human keratinocyte2016

    • Author(s)
      Hidetoshi Tsuda, Mayumi Komine, Shin-ichi Tominaga, Mamitaro Ohtsuki
    • Organizer
      46th Annual Meeting of European Society for Dermatological Research
    • Place of Presentation
      Munchen, Germany
    • Year and Date
      2016-09-07
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10172
  • [Presentation] Double-stranded RNA induces IL-33 expression through activation of EGFR, ERK, and p38 in normal human epidermal keratinocytes.2016

    • Author(s)
      Meijuan Jin, Mayumi Komine, Hidetoshi Tsuda, Mamitaro Ohtsuki
    • Organizer
      46th Annual Meeting of European Society for Dermatological Research
    • Place of Presentation
      Munchen, Germany
    • Year and Date
      2016-09-07
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10172
  • [Presentation] Analysis of Oncostatin M signaling in Hemangiosarcoma Cell Line and Regulation of IL-33 Expression2016

    • Author(s)
      Hidetoshi Tsuda, Mayumi Komine, Meijuan Jin, Naomi Nakano, Shin-ichi Tominaga, Mikio Masuzawa, Mamitaro Ohtsuki
    • Organizer
      41th Annual Meeting of Japanese Society for Investigative Dermatology
    • Place of Presentation
      仙台国際センター、宮城県、仙台市
    • Year and Date
      2016-12-09
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10172
  • [Presentation] IL-33 is expressed in lesional skin of herpes virus infection,but not of verruca vulgaris.2016

    • Author(s)
      Meijuan Jin, Mayumi Komine, Hidetoshi Tsuda, Shin-ichi Tominaga, Mamitaro Ohtsuki
    • Organizer
      75th Annual Meeting of Society for Investigative Dermatology
    • Place of Presentation
      Scottsdale, USA
    • Year and Date
      2016-05-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10172
  • [Presentation] ケラチノサイトにおけるヒトIL-33プロモーター領域の解析2013

    • Author(s)
      津田英利・小宮根真弓・大塩智之・富永眞一・大槻マミ太郎
    • Organizer
      第36回日本分子生物学学会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-23591652
  • [Presentation] IL-33ノックダウンにより正常ヒト表皮角化細胞の細胞周期はG1/SからG2/M期へシフトする2013

    • Author(s)
      津田英利、小宮根真弓、大塩智之、富永眞一、大槻マミ太郎
    • Organizer
      日本分子生物学会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-23591652
  • [Presentation] IL-33 affects proliferation and differentiation of normal human epidermal keratinocytes2013

    • Author(s)
      Tsuda H, Komine M, Oshio T, Tominaga S, Ohtsuki M
    • Organizer
      International Investigative Dermatology
    • Place of Presentation
      Edinburgh
    • Data Source
      KAKENHI-PROJECT-23591652
  • [Presentation] IL-33 as a nuclear protein to affect proliferation and differentiation of normal human epidermal keratinocytes2013

    • Author(s)
      Hidetoshi Tsuda, Mayumi Komine, Tomoyuki Ohshio, Shin-ichi Tominaga, Mamitaro Ohtsuki
    • Organizer
      International Investigative Dermatology
    • Place of Presentation
      Edinburgh, UK
    • Data Source
      KAKENHI-PROJECT-23591652
  • [Presentation] IL-33 as a nuclear protein to affect proliferation and differentiation of normal human epidermal keratinocytes2013

    • Author(s)
      Hidetoshi Tsuda, Mayumi Komine, Tomoyuki Ohshio, Shin-ichi Tominaga, Mamitaro Ohtsuki
    • Organizer
      International Investigative Dermatology
    • Place of Presentation
      Edinburgh, Scotland
    • Data Source
      KAKENHI-PROJECT-23591652
  • [Presentation] IL-17 up regulates IL-33 expression in keratinocytes; negative feedback loop in psoriatic epidermis.2012

    • Author(s)
      Meephansan, J., Tsuda, H., Komine, M., Karakawa, M., Tominaga, S., Ohtsuki, M.
    • Organizer
      The 42nd Annual ESDR (European Society for Dermatological Research) Meeting.
    • Place of Presentation
      Venice, Italy
    • Data Source
      KAKENHI-PROJECT-22590289
  • [Presentation] IL-17 up regulates IL-33 expression in keratinocytes; negative feedback loop in psoriatic epidermis2012

    • Author(s)
      Meephansan, J., Tsuda, H., Komine, M., Karakawa, M., Tominaga, S., Ohtsuki, M
    • Organizer
      The 42ndAnnual ESDR (European Society for Dermatological Research)Meeting
    • Place of Presentation
      Venice, Italy
    • Data Source
      KAKENHI-PROJECT-22590289
  • [Presentation] IL-33 is produced by normal human keraitnocytes with environmental and inflammatory stimuli: a novel “alarmin” in the skin.2012

    • Author(s)
      Jitlada Meephansan, Mayumi Komine, Hidetoshi Tsuda, Shoichiro Yano, Shin-ichi Tominaga, Mamitaro Ohtsuki
    • Organizer
      Society for Investigative Dermatology
    • Place of Presentation
      Raleigh, USA
    • Data Source
      KAKENHI-PROJECT-23591652
  • [Presentation] IL-33は核内でケラチノサイトの細胞増殖に関与している。2012

    • Author(s)
      Tsuda, H., Komine, M., Oshio, T., Tominaga, S., Ohtsuki, M.
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-22590289
  • [Presentation] IL-33 is produced by normal human keraitnocytes with environmental and inflammatory stimuli : a novel"alarmin"in the skin2012

    • Author(s)
      Jitlada Meephansan, Mayumi Komine, Hidetoshi Tsuda, Shin-ichi Tominaga, Mamitaro Ohtsuki
    • Organizer
      Annual meeting of Society for Investigative Dermatology
    • Place of Presentation
      North Carolina, USA
    • Data Source
      KAKENHI-PROJECT-23591652
  • [Presentation] IL-17A up regulates IL-33 expression in keratinocytes; negative feedback loop in psoriatic epidermis2012

    • Author(s)
      Jitlada Meephansan, Mayumi Komine, Hidetoshi Tsuda, Shin-ichi Tominaga, Mamitaro Ohtsuki
    • Organizer
      Annual meeting of European Society for Dermatological Research
    • Place of Presentation
      Venice, Italy
    • Data Source
      KAKENHI-PROJECT-23591652
  • [Presentation] Regulation of IL-33 expression by interferon-gamma and tumor necrosis factor-alpha in normal human epidermal keratinocytes.2012

    • Author(s)
      Meephansan, J., Tsuda, H., Komine, M., Karakawa, M., Tominaga, S., Ohtsuki, M.
    • Organizer
      Annual Meeting of the Society for Investigative Dermatology.
    • Place of Presentation
      Raleigh, North Carolina, USA
    • Data Source
      KAKENHI-PROJECT-22590289
  • [Presentation] Regulation of IL-33 by inflammatory cytokines in normal human epidermal keratinocytes2012

    • Author(s)
      Jitlada Meephansan, Mayumi Komine, Hidetoshi Tsuda, Shin-ichi Tominaga, Mamitaro Ohtsuki
    • Organizer
      東京皮膚フォーラム
    • Place of Presentation
      丸の内、東京
    • Year and Date
      2012-03-03
    • Data Source
      KAKENHI-PROJECT-23591652
  • [Presentation] Regulation of IL-33 expression by inflammatory cytokines and its putative role in inflammatory skin disorders2012

    • Author(s)
      Jitlada Meephansan, Mayumi Komine, Hidetoshi Tsuda, Shin-ichi Tominaga, Mamitaro Ohtsuki
    • Organizer
      Annual Meeting of Japanese Society for Investigative Dermatology
    • Place of Presentation
      沖縄
    • Data Source
      KAKENHI-PROJECT-23591652
  • [Presentation] Regulation of IL-33 expression by inflammatory cytokines and its putative role in inflammatory skin disorders2012

    • Author(s)
      Jitlada Meephansan, Mayumi Komine, Hidetoshi Tsuda, Tomoyuki Oshio, Masaru Karakawa, Shin-ichi Tominaga, Mamitaro Ohtsuki
    • Organizer
      Japanese Society for Investigative Dermatology
    • Place of Presentation
      Okinawa
    • Data Source
      KAKENHI-PROJECT-23591652
  • [Presentation] Nuclear IL-33 in relation to proliferation and cell cycle of normal human epidermal keratinocytes2012

    • Author(s)
      Tsuda, H., Komine, M., Oshio, T., Tominaga, S., Ohtsuki, M
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      福岡
    • Year and Date
      2012-12-11
    • Data Source
      KAKENHI-PROJECT-22590289
  • [Presentation] Regulation of IL-33 expression by interferon-gamma and tumor necrosis factor-alpha in normal human epidermal keratinocytes.2012

    • Author(s)
      Meephansan, J., Tsuda, H., Komine, M., Karakawa, M., Tominaga, S., Ohtsuki, M
    • Organizer
      Annual Meeting of the Society for Investigative Dermatology
    • Place of Presentation
      Raleigh, North Carolina, USA
    • Data Source
      KAKENHI-PROJECT-22590289
  • [Presentation] Novel splice variants of IL-33 expressed in normal human keratinocyte2012

    • Author(s)
      Hidetoshi Tsuda, Mayumi Komine, Tomoyuki Oshio, Satomi Hosoda, Shin-ichi Tominaga, Mamitaro Ohtsuki
    • Organizer
      Annual Meeting of Japanese Society for Investigative Dermatology
    • Place of Presentation
      沖縄
    • Data Source
      KAKENHI-PROJECT-23591652
  • [Presentation] Regulation of IL-33 by inflammatory cytokines in normal human epidermal keratinocytes2012

    • Author(s)
      Jitlada Meephansan, Hidetoshi Tsuda, Mayumi Komine, Satomi Hosoda, Shin-ichi Tominaga, Mamitaro Ohtsuki
    • Organizer
      分子皮膚科フォーラム
    • Place of Presentation
      青森
    • Year and Date
      2012-04-13
    • Data Source
      KAKENHI-PROJECT-23591652
  • [Presentation] Retinoids regulates the production of matrix metalloproteinases in the human epidermal keratinocyte cell line HaCaT2012

    • Author(s)
      Satomi Hosoda, Mayumi Komine, Masaru Karakawa, Jitlada Meephansanm, Hidetoshi Tsuda, Mamitaro Ohtsuki
    • Organizer
      Annual Meeting of Japanese Society for Investigative Dermatology
    • Place of Presentation
      沖縄
    • Data Source
      KAKENHI-PROJECT-23591652
  • [Presentation] IL-33 is produced by normal human keraitnocytes with environmental and inflammatory stimuli: a novel "alarmin" in the skin2011

    • Author(s)
      Meephansan J, Komine M, Tsuda H, Yano S, Tominaga S, Ohtsuki M.
    • Organizer
      74th Society for Investigative Dermatology
    • Place of Presentation
      USA
    • Data Source
      KAKENHI-PROJECT-23591652
  • [Presentation] IL-33は核内でケラチノサイトのproliferationに関与している2011

    • Author(s)
      津田英利・小宮根真弓・大塩智之・富永眞一・大槻マミ太郎
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-23591652
  • [Presentation] IL-33 is produced by normal human keratinocytes with environmental and inflammatory stimuli: A novel "alarmin" in the skin2011

    • Author(s)
      Meephansan, J., Komine, M., Tsuda, H., Yano, S., Tominaga, S., Ohtsuki, M
    • Organizer
      Annual Meeting of the Society for Investigative Dermatology
    • Place of Presentation
      Phoenix, Arizona, USA
    • Data Source
      KAKENHI-PROJECT-22590289
  • [Presentation] Novel splicing variants of IL-33 and its expression variation2011

    • Author(s)
      Tsuda, H., Meephansan, J., Karakawa, M., Tominaga, S., Komine, M., and Ohtsuki, M.
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2011-12-15
    • Data Source
      KAKENHI-PROJECT-22590289
  • [Presentation] Environmental stimuli up regulate IL-33 in normal human keratinocytes.2010

    • Author(s)
      Meephansan, J., Komine, M., Wakatabi, K., Tominaga, S., Ohtsuki, M.
    • Organizer
      Annual Meeting of the Society for Investigative Dermatology
    • Place of Presentation
      Atlanta, Georgia, USA
    • Data Source
      KAKENHI-PROJECT-22590289
  • [Presentation] Calcipotriol reduced induction of MMP-9 and MMP-13 in human squamous cell carcinoma cell line2010

    • Author(s)
      Meephansan J, Komine M, Ohtsuki M.
    • Organizer
      40th European Society for Dermatologial Research
    • Place of Presentation
      Helsinki
    • Data Source
      KAKENHI-PROJECT-23591652
  • [Presentation] 先天性魚鱗癬様紅皮症の皮疹形成機序と治療に関する研究2008

    • Author(s)
      小宮根 真弓
    • Organizer
      稀少難治性皮膚疾患に関する調査研究班、 平成19年度第2回会議
    • Place of Presentation
      東京
    • Year and Date
      2008-01-11
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Presentation] 乾癬に対する光線療法2008

    • Author(s)
      小宮根 真弓
    • Organizer
      第7回つくば皮膚フォロム
    • Place of Presentation
      茨城
    • Year and Date
      2008-03-13
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Presentation] アトピー性皮膚炎の病態におけるケラチノサイトの役割2008

    • Author(s)
      小宮根 真弓
    • Organizer
      第81回 日本薬理学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2008-03-19
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Presentation] バイオロジックスと乾癬の病態理論の深化2008

    • Author(s)
      小宮根真弓
    • Organizer
      第 回乾癬学会ランチョンセミナー
    • Place of Presentation
      旭川
    • Year and Date
      2008-09-06
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Presentation] 抗菌剤の新しい作用2008

    • Author(s)
      小宮根真弓
    • Organizer
      107回日本皮膚科学会総会 イブニングセミナー
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Presentation] 乾癬における細胞2008

    • Author(s)
      小宮根 真弓
    • Organizer
      第1回 PREMIUM Workshop
    • Place of Presentation
      東京
    • Year and Date
      2008-03-15
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Presentation] Existence of numerous CD1a- and RANKL-positive dendritic cells in the papillary dermis of psoriatic plaques.2008

    • Author(s)
      小宮根真弓他
    • Organizer
      International Investigative Dermatology
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Presentation] Existence of numerous CDla- and RANKL-positive dendritic cells in the papillary dermis of psoriatic plaques.2008

    • Author(s)
      小宮根真弓, 他
    • Organizer
      International Investigative Dermatology
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Presentation] アトピー性皮膚炎における表皮細胞の役割2008

    • Author(s)
      小宮根真弓
    • Organizer
      日本薬理学会シンポジウム
    • Place of Presentation
      横浜
    • Year and Date
      2008-03-19
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Presentation] Herpes gestationis in association with a complete hydatidiform mole2008

    • Author(s)
      Yuka Takatsuka、Mayumi Komine、et al.
    • Organizer
      Japan-China Dermatology meeting
    • Place of Presentation
      杭州
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Presentation] 乾癬の病態:表皮側から2008

    • Author(s)
      小宮根真弓
    • Organizer
      第 回乾癬学会シンポジウム
    • Place of Presentation
      旭川
    • Year and Date
      2008-09-05
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Presentation] The effects of mechanical stretch on normal human epidermal keratinocytes.2007

    • Author(s)
      Mayumi Komine, Yasushi Hanakawa, Hitoshi Okochi, Koji Sayama, Koji Hashimoto, Miroslav Blumenberg, Kunihiko Tamaki
    • Organizer
      第32 回 日本研究皮膚科学会
    • Place of Presentation
      東京(横浜)
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Presentation] Early inflammatory in the "peri-lesional skin" of psoriatic plaques: Is there interaction between dendritic cells and keratinocytes?2007

    • Author(s)
      Mayumi Komine, Masaru Karakawa, Tomonori Takekoshi, Naoki sakurai, Yosaku Minatani, Hiroshi Mitsui, Yayoi Tada, Hidehisa Saeki, Akihiko Asahina, Kunihiko Tamaki
    • Organizer
      the 63th Annual meeting of Society for Investigative Dermatology
    • Place of Presentation
      Los Angeles, USA
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Presentation] 膿疱性乾癬皮疹部における樹状細胞と表皮細胞からのiNOS産生2007

    • Author(s)
      小宮根真弓、大槻マミ太郎、唐川大、竹腰知紀、柴田彩、多田弥生、佐伯秀久、玉置邦彦
    • Organizer
      第22 回日本乾癬学会
    • Place of Presentation
      三重(伊勢志摩)
    • Year and Date
      2007-09-07
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Presentation] 水疱型先天性魚鱗癬様紅皮症のケラチン1変異による表皮細胞への影響2007

    • Author(s)
      小宮根 真弓
    • Organizer
      稀少難治性皮膚疾患に関する調査研究班平成19年度第1回班会議
    • Place of Presentation
      東京
    • Year and Date
      2007-08-03
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Presentation] 掌せき膿庖症に対するマクロライドの効果2007

    • Author(s)
      小宮根 真弓
    • Organizer
      第5回 皮膚マクロライド研究会
    • Place of Presentation
      東京
    • Year and Date
      2007-06-30
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Presentation] ケラチノサイトの生物学2007

    • Author(s)
      小宮根真弓
    • Organizer
      第106回日本皮膚科学会総会教育講演
    • Place of Presentation
      東京(横浜)
    • Year and Date
      2007-04-22
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Presentation] 生物学的製剤2007

    • Author(s)
      小宮根真弓
    • Organizer
      第106回日本皮膚科学会総会ランチョンセミナー
    • Place of Presentation
      東京(横浜)
    • Year and Date
      2007-04-20
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Presentation] Early inflammatory in the "peri-lesional skin" of psoriatic plaques: Is there interaction between dendritic cells and keratinocytes?2007

    • Author(s)
      Mayumi Komine, Masaru Karakawa, Tomonori Takekoshi, Naoki sakurai, Yosaku Minatani, Hiroshi Mitsui, Yayoi Tada, Hidehisa Saeki, Akihiko Asahina, Kunihiko Tamaki
    • Organizer
      the 10^<th> International Langerhans cell meeting
    • Place of Presentation
      Bern, Switzerland
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Presentation] ケラチノサイトの生物学2007

    • Author(s)
      小宮根 真弓
    • Organizer
      第106回日本皮膚科学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2007-04-22
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Presentation] NB-UVBによる乾癬治療-東京大学における経験2007

    • Author(s)
      小宮根 真弓
    • Organizer
      第10回 栃木乾癬研究会
    • Place of Presentation
      栃木
    • Year and Date
      2007-10-25
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Presentation] 表皮細胞に対するマクロライドの作用2007

    • Author(s)
      小宮根 真弓
    • Organizer
      第5回 皮膚マクロライド研究会
    • Place of Presentation
      東京
    • Year and Date
      2007-06-30
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Presentation] 抗菌剤の特性を生かす2007

    • Author(s)
      小宮根真弓
    • Organizer
      第106回日本皮膚科学会総会モーニングセミナー
    • Place of Presentation
      東京(横浜)
    • Year and Date
      2007-04-22
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Presentation] 膿疱性乾癬皮診部における樹状細胞と表皮細胞からのiNOS産生2007

    • Author(s)
      小宮根 真弓
    • Organizer
      第22回 日本乾癬学会
    • Place of Presentation
      三重
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Presentation] 女性と乾癬、第12回乾癬学習会、11月3日、東京2007

    • Author(s)
      小宮根 真弓
    • Organizer
      第12回 乾癬学習会
    • Place of Presentation
      東京
    • Year and Date
      2007-11-03
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Presentation] 水疱型魚鱗癬様紅皮症患者者表皮におけるbFGF表現2007

    • Author(s)
      小宮根 真弓
    • Organizer
      bFGF創傷治癒研究会
    • Place of Presentation
      東京
    • Year and Date
      2007-12-07
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Presentation] Early inflammatory in the "peri-lesional skin" of psoriatic plaques:Is threr interaction between dendritic cells and keratinocytes?2007

    • Author(s)
      小宮根 真弓
    • Organizer
      第10回 International Langerhans cell meeting
    • Place of Presentation
      ベルン、スイス
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Presentation] Early inflammatory in the "peri-lesional skin" of psoriatic plaques:IS there interaction between dendritic cells and keratinocytes?2007

    • Author(s)
      小宮根 真弓
    • Organizer
      第63回米国研究皮膚科学会
    • Place of Presentation
      ロサンゼルス アメリカ合衆国
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Presentation] 興味深い皮膚科の臨床2007

    • Author(s)
      小宮根 真弓
    • Organizer
      両毛地区皮膚科フォーラム
    • Place of Presentation
      栃木
    • Year and Date
      2007-09-13
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Presentation] The effects of mechanical stretch on normal human epidermal keratinocytes2007

    • Author(s)
      小宮根 真弓
    • Organizer
      第32回日本研究皮膚科学会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Presentation] 抗菌剤の特性を生かす2007

    • Author(s)
      小宮根 真弓
    • Organizer
      第106回日本皮膚科学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2007-04-22
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Presentation] 水疱型先天性魚鱗癬様紅皮症のケラチン1変異による表皮細胞への影響、稀少難治性皮膚疾患に関する調査研究班2007

    • Author(s)
      小宮根真弓、花川 靖、橋本公二、大河内仁志、玉置邦彦
    • Organizer
      平成19年度第1回班会議
    • Place of Presentation
      東京
    • Year and Date
      2007-08-03
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Presentation] 表皮細胞における変異ケラチンK1の作用2006

    • Author(s)
      小宮根真弓、花川 靖、常深祐一郎、佐々木苗胤、大河内仁志、橋本公二、玉置邦彦
    • Organizer
      第21回角化症研究会
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Presentation] Mechanical stretch induces extracellular matrix proteins, adhesion molecules, and actin-related cytoskeleton proteins, by regulating Rho, cdc42 and Rac family gene expression in normal human keratinocytes.2006

    • Author(s)
      Mayumi Komine, Shoichiro Yano, Hitoshi Okochi, Miroslav Blumenberg, Kunihiko Tamaki
    • Organizer
      第67回米国研究皮膚科学会
    • Place of Presentation
      フィラデルフィア、アメリカ合衆国
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Presentation] 尋常性乾癬局面および膿疱性乾癬病変部における樹状細胞についての免疫組織学的検討2006

    • Author(s)
      小宮根真弓、竹腰知紀、桜井直樹、南谷洋策、佐伯秀久、朝比奈昭彦、玉置邦彦
    • Organizer
      第21回日本乾癬学会
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Presentation] Immunohistochemical Study of NB-UVB-treated Skin of Psoriasis Patients2006

    • Author(s)
      Komine M, Deng D, Takekoshi T, Sakurai N, Minatani M, Saeki H, Asahina A, Tamaki K
    • Organizer
      第10回日本・中国合同皮膚科学会
    • Place of Presentation
      成都、中国
    • Data Source
      KAKENHI-PROJECT-18591236
  • [Presentation] Immunohistochemical characterization of the marginal lesion of psoriatic plaques2006

    • Author(s)
      Komine M, Takekoshi T, Sakurai N, Minatani M, Saeki H, Asahina A, Tamaki K.
    • Organizer
      第31回日本研究皮膚科学会
    • Data Source
      KAKENHI-PROJECT-18591236
  • []

  • 1.  WATANABE Takahiro (30280960)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 2.  TAMAKI Kunihiko (30010432)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 6 results
  • 3.  ASAHINA Akihiko (50202601)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 4.  KAKINUMA Takashi (30332604)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 5.  Higashi Nobuaki (40302616)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 6.  小宮根 真弓 (50215406)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  津田 英利 (30414923)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 20 results
  • 8.  TADA Yayoi (00334409)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 9.  TOMINAGA Shinichi (70155571)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 14 results
  • 10.  TAMEMOTO Hiroyuki (90292630)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 11.  HAYAKAWA Morisada (30326847)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  SAEKI Hidehisa (80235093)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  KIKUCHI Kanako (60186195)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  KADONO Takafumi (80292910)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  東 恭平 (10463829)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 16.  福澤 薫 (50718244)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  眞鍋 史乃 (60300901)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  松村 貴由 (80436485)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  Jin Meijuan
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 9 results
  • 20.  TAGO Megumi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 21.  EGAWA Gyohei
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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