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NANKI Toshihiro  南木 敏宏

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… Alternative Names

南木 敏宏  ナンキ トシヒロ

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Researcher Number 00282749
Other IDs
Affiliation (Current) 2022: 東邦大学, 医学部, 教授
Affiliation (based on the past Project Information) *help 2021: 東邦大学, 医学部, 教授
2016 – 2019: 東邦大学, 医学部, 教授
2016: 帝京大学, 医学部, 准教授
2015: 東邦大学, 医学部, 准教授
2013 – 2014: 帝京大学, 医学部, 准教授 … More
2012: 東京医科歯科大学, 医歯(薬)学総合研究科, 寄附講座准教授
2011: 東京医科歯科大学, 医歯(薬)学総合研究科, 寄付講座准教授
2011: 東京医科歯科大学, 医歯(薬)学総合研究科, 寄附講座教員
2010: 東京医科歯科大学, 大学院・医歯学総合研究科, 准教授
2010: Tokyo Medical and Dental University, 大学院・医歯学総合研究科, 寄附講座教員
2009: Tokyo Medical and Dental University, 医歯学総合研究科, 寄附講座教員
2008: Tokyo Medical and Dental University, 大学院・医歯学総合研究科, 寄附講座准教授
2001 – 2004: 東京医科歯科大学, 大学院・医歯学総合研究科, 助手 Less
Review Section/Research Field
Principal Investigator
膠原病・アレルギー・感染症内科学 / 内科学一般 / Collagenous pathology/Allergology
Except Principal Investigator
Collagenous pathology/Allergology / 膠原病・アレルギー・感染症内科学 / Applied pharmacology / Medical pharmacy / Cardiovascular medicine / Basic Section 54020:Connective tissue disease and allergy-related
Keywords
Principal Investigator
関節リウマチ / ケモカイン / ケモカインレセプター / フラクタルカイン / 慢性関節リウマチ / サイトカイン / 血管炎 / 血管炎症候群 / CX3CR1 / カンナビノイド / 単球 / 破骨細胞 / 樹状細胞 … More
Except Principal Investigator
… More 関節リウマチ / 生物学的製剤 / 自然炎症 / ケモカイン / ケモカインレセプター / TNF阻害薬 / 薬剤疫学 / 安全性 / 患者登録システム / 重篤有害事象 / 薬剤適正使用 / 悪性腫瘍 / リウマチ性疾患 / 免疫抑制療法 / 肺感染症 / 日和見感染症 / 膠原病 / 分子標的薬 / 重篤肺感染症 / 日和見肺感染症 / 薬剤疫学研究 / 膠原病学 / 抗好中球細胞質抗体関連血管炎 / NETS形成 / シトルリン化 / 自然免疫 / インフラマソーム / リウマチ学 / IL-1 / NLRP3 / Notch / 炎症性メディエーター / 高齢者 / 治療戦略 / 身体機能 / 疾患感受性遺伝子 / 核内タンパク質シトルリン化酵素 / 全エクソン領域関連解析 / PAD4 / 低疾患活動性を目標とした治療 / PPID / 機能的多型 / 治療反応性予測因子 / 安全性予測因子 / PAD4 / 動脈硬化 / HDL / ATF3 / TLR / lung fibrosis / lung microbiota / senescence / p21 / p16 / SASP / 間質性肺炎 / 肺細菌叢 / 細胞老化 / 2型肺胞上皮 Less
  • Research Projects

    (14 results)
  • Research Products

    (78 results)
  • Co-Researchers

    (32 People)
  •  Mechanisms for the involvement of airway microbiota in RA-associated interstitial lung disease

    • Principal Investigator
      西尾 純子
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54020:Connective tissue disease and allergy-related
    • Research Institution
      Toho University
  •  Role of fractalkine in monocytes in patients with rheumatoid arthritisPrincipal Investigator

    • Principal Investigator
      NANKI TOSHIHIRO
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Collagenous pathology/Allergology
    • Research Institution
      Toho University
  •  Innate immunity in the pathogenesis of rheumatoid arthritis

    • Principal Investigator
      Hajime Kono
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Collagenous pathology/Allergology
    • Research Institution
      Teikyo University
  •  Notchリガンド分子阻害による関節炎抑制機序の解明

    • Principal Investigator
      関根 知世子
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Collagenous pathology/Allergology
    • Research Institution
      Teikyo University
  •  Establishment of treatment strategy of elderly rheumatoid arthritis based on treat-to-target strategy, Peptidylarginine Deiminase 4, and single nucleotide polymorphisms

    • Principal Investigator
      Sugihara Takahiko
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Collagenous pathology/Allergology
    • Research Institution
      Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
  •  The anti-inflammatory mechanism of HDL in atherosclerosis

    • Principal Investigator
      KONO Hajime
    • Project Period (FY)
      2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Cardiovascular medicine
    • Research Institution
      Teikyo University
  •  Development a novel therapy targeting NETs formation for anti-neutrophil cytoplasmic antibody-associated vasculitis

    • Principal Investigator
      HARIGAI Masayoshi
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Tokyo Medical and Dental University
  •  The pharmaco-epidemiological study about serious and opportunistic infections under treatment of the biologics and the molecular target medicine.

    • Principal Investigator
      TANAKA Michi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      Tokyo Medical and Dental University
  •  Cannabinoid Receptor 2 as a potential therapeutic target in Rheumatoid ArthritisPrincipal Investigator

    • Principal Investigator
      NANKI Toshihiro
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Teikyo University
      Tokyo Medical and Dental University
  •  A epidemiological study of long-term safety of biological disease-modifying antirheumatic drugs for patients with rheumatoid arthritis and risk factors for adverse drug reactions.

    • Principal Investigator
      HARIGAI Masayoshi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied pharmacology
    • Research Institution
      Tokyo Medical and Dental University
  •  Effect of fractalkine blockade on vasculitis syndromePrincipal Investigator

    • Principal Investigator
      NANKI Toshihiro
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Tokyo Medical and Dental University
  •  新規ケモカインCXCL16を介する関節リウマチ病態形成の分子機構の解明

    • Principal Investigator
      MIYASAKA Nobuyuki
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Tokyo Medical and Dental University
  •  ケモカイン・ケモカインレセプター阻害剤による関節リウマチに対する新規治療薬の開発Principal Investigator

    • Principal Investigator
      南木 敏宏
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Tokyo Medical and Dental University
  •  慢性関節リウマチの病変関節におけるケモカイン・ケモカインレセプターの解析Principal Investigator

    • Principal Investigator
      南木 敏宏
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      内科学一般
    • Research Institution
      Tokyo Medical and Dental University

All 2022 2021 2019 2018 2014 2013 2012 2011 2010 2009 2008 2005 2004 Other

All Journal Article Presentation Book

  • [Book] Retinoic Acid and Immunity. Vitamin-Binding Proteins - Functional Consequences. Ed. Krishnamurti Dakshinamurti and Shyamala Dakshinamurti2013

    • Author(s)
      Yoshishige Miyabe, Chie Miyabe, Toshihiro Nanki
    • Publisher
      CRC Press/Taylor & Francis Group
    • Data Source
      KAKENHI-PROJECT-23591435
  • [Book] 製剤ごとの感染症とその頻度について教えて下さい、ファーマナビゲーターリウマチ~生物学的製剤編~2010

    • Author(s)
      南木敏宏
    • Total Pages
      4
    • Publisher
      メディカル・レビュー社
    • Data Source
      KAKENHI-PROJECT-20591166
  • [Book] 製剤ごとの感染症とその頻度について教えて下さい ファーマナビゲーターリウマチ-生物学的製剤編- (竹内勤編)2010

    • Author(s)
      南木敏宏
    • Publisher
      メディカル・レビュー社
    • Data Source
      KAKENHI-PROJECT-20591166
  • [Book] 非ステロイド性抗炎症薬の適応と副作用 よくわかる関節リウマチのすべて (宮坂信之編)2009

    • Author(s)
      南木敏宏
    • Publisher
      永井書店
    • Data Source
      KAKENHI-PROJECT-20591166
  • [Book] アレルギー・膠原病系症状と検査異常。症状・所見。筋肉痛。チャート内科診断学。2009

    • Author(s)
      南木敏宏
    • Total Pages
      3
    • Publisher
      中外医薬社
    • Data Source
      KAKENHI-PROJECT-20591166
  • [Book] アレルギー・膠原病系症状と検査異常 症状・所見 筋肉痛 チャート内科診断学 (富野康日己編)2009

    • Author(s)
      南木敏宏
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-20591166
  • [Journal Article] Treatment with an Anti-CX3CL1 Antibody Suppresses M1 Macrophage Infiltration in Interstitial Lung Disease in SKG Mice2021

    • Author(s)
      Mizutani Satoshi、Nishio Junko、Kondo Kanoh、Motomura Kaori、Yamada Zento、Masuoka Shotaro、Yamada Soichi、Muraoka Sei、Ishii Naoto、Kuboi Yoshikazu、Sendo Sho、Mikami Tetuo、Imai Toshio、Nanki Toshihiro
    • Journal Title

      Pharmaceuticals

      Volume: 14 Pages: 474-474

    • DOI

      10.3390/ph14050474

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07166, KAKENHI-PROJECT-21K08482
  • [Journal Article] CX3CL1/fractalkine regulates the differentiation of human peripheral blood monocytes and monocyte-derived dendritic cells into osteoclasts2021

    • Author(s)
      Muraoka Sei、Kaneko Kaichi、Motomura Kaori、Nishio Junko、Nanki Toshihiro
    • Journal Title

      Cytokine

      Volume: 146 Pages: 155652-155652

    • DOI

      10.1016/j.cyto.2021.155652

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07166, KAKENHI-PROJECT-21K08482
  • [Journal Article] Macrophage-derived delta-like protein 1 enhances interleukin-6 and matrix metalloproteinase 3 production by fibroblast-like synoviocytes in mice with collagen-induced arthritis.2014

    • Author(s)
      Sekine C, Nanki T, Yagita H
    • Journal Title

      Arthritis Rheumatol

      Volume: 66 Pages: 2751-61

    • DOI

      10.1002/art.38743

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26461475
  • [Journal Article] Activation of fibroblast-like synoviocytes derived from rheumatoid arthritis via lysophosphatidic acid-lysophosphatidic acid receptor 1 cascade.2014

    • Author(s)
      Miyabe Y, Miyabe C, Iwai Y, Yokoyama W, Sekine C, Sugimoto K, Harigai M, Miyasaka M, Miyasaka N, Nanki T.
    • Journal Title

      Arthritis Res Ther

      Volume: 16 Pages: 461-461

    • DOI

      10.1186/s13075-014-0461-9

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111005, KAKENHI-PROJECT-26461475
  • [Journal Article] CCL18 activates fibroblast-like synoviocytes in patients with rheumatoid arthritis2013

    • Author(s)
      Takayasu A, Miyabe Y, Yokoyama W, Kaneko K, Miyabe C, Fukuda S, Kubota T, Miyasaka N, Nanki T
    • Journal Title

      J. Rheumatol

      Volume: 40 Pages: 1026-1028

    • DOI

      10.3899/jrheum.121412

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591435
  • [Journal Article] Am80, a retinoic acid receptor agonist, ameliorates murine vasculitis through the suppression of neutrophil migration and activation.2013

    • Author(s)
      Miyabe C, Miyabe Y, Miura NN, Takahashi K, Terashima Y, Toda E, Honda F, Morio T, Yamagata N, Ohno N, Shudo K, Suzuki J, Isobe M, Matsushima K, Tsuboi R, Miyasaka N, Nanki T
    • Journal Title

      Arthritis Rheumatism.

      Volume: 65 Pages: 503-512

    • DOI

      10.1002/art.37784

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591435, KAKENHI-PROJECT-23659518, KAKENHI-PROJECT-25670472
  • [Journal Article] Suppression of elevations in serum Creactive protein levels by anti-IL-6autoantibodies in two patients withsevere bacterial infections2013

    • Author(s)
      Nanki T, Onoue I, Nagasaka K, Takayasu A, Ebisawa M, Hosoya T, Shirai T, Sugihara T, Hirata S, Kubota T, Harigai M, Miyasaka N
    • Journal Title

      Ann Rheum Dis.

      Volume: 72 Pages: 1100-1102

    • DOI

      10.1136/annrheumdis-2012-202768

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591435, KAKENHI-PROJECT-23791109, KAKENHI-PROJECT-25461499
  • [Journal Article] CXCR7 agonists inhibit the function of CXCL12 by down-regulation of CXCR4.2013

    • Author(s)
      Uto-Konomi A, McKibben B, Wirtz J, Sato Y, Takano A, Nanki T, Suzuki S
    • Journal Title

      Biochem Biophys. Res. Commun

      Volume: 431 Pages: 772-776

    • DOI

      10.1016/j.bbrc.2013.01.032

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591435
  • [Journal Article] Clinical characteristics and risk factors for Pneumocystis jirovecii pneumonia in patients with rheumatoid arthritis receiving adalimumab : a retrospective review and case-control study of 17 patients2013

    • Author(s)
      Watanabe K, Sakai R, Koike R, Sakai F, Sugiyama H, Tanaka M, Komano Y, Akiyama Y, Mimura T, Kaneko M, Tokuda H, Iso T, Motegi M, Ikeda K, Nakajima H, Taki H, Kubota T, Kodama H, Sugii S, Kuroiwa T, Nawata Y, Shiozawa K, Ogata A, Sawada S, Matsukawa Y, Okazaki T, Mukai M, Iwahashi M, Saito K, Tanaka Y, Nanki T, Miyasaka N, Harigai M
    • Journal Title

      Mod Rheumatol

      Volume: 23(6) Pages: 1085-93

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590171
  • [Journal Article] Necessity of lysophosphatidic acid receptor 1 for development of arthritis2013

    • Author(s)
      Miyabe Y, Miyabe C, Iwai Y, Takayasu A, Fukuda S, Yokoyama W, Nagai J, Jona M, Tokuhara Y, Ohkawa R, Albers HM, Ovaa H, Aoki J, Chun J, Yatomi Y, Ueda H, Miyasaka M, Miyasaka N, Nanki T
    • Journal Title

      Arthritis & Rheumatism

      Volume: 65 Pages: 2037-2037

    • DOI

      10.1002/art.37991

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591435, KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111005, KAKENHI-PROJECT-24790576
  • [Journal Article] Serum level of soluble CX3CL1/fractalkine is elevated in patients with polymyositis and dermatomyositis, which is correlated with disease activity.2012

    • Author(s)
      Suzuki F, Kubota T, Miyazaki Y, Ishikawa K, Ebisawa M, Hirohata S, Ogura T, Mizusawa H, Imai T, Miyasaka N, Nanki T
    • Journal Title

      Arthritis Res Ther

      Volume: 14

    • DOI

      10.1186/ar3761

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591435, KAKENHI-PROJECT-23591447
  • [Journal Article] Arthritic joint-targeting small interfering RNA-encapsulated liposome : Implication for treatment strategy for rheumatoid arthritis2012

    • Author(s)
      Komano Y, Yagi N, Onoue I, Kaneko K, Miyasaka N, Nanki T
    • Journal Title

      J. Pharmacol. Exp. Ther

      Volume: 340 Pages: 109-113

    • DOI

      10.1124/jpet.111.185884

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591435
  • [Journal Article] Chemerin activates fibroblast-like synoviocytes in patients with rheumatoid arthritis2011

    • Author(s)
      Kayoko Kaneko, et al
    • Journal Title

      Arthritis Res. Ther

      Volume: 13

    • DOI

      10.1186/ar3475

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19059004, KAKENHI-PROJECT-23591435
  • [Journal Article] The effect of synthetic retinoid, Am80, on T helper cell development and antibody production in murine collagen-induced arthritis.2010

    • Author(s)
      Sato A, Watanabe K, Kaneko K, Murakami Y, Ishido M, Miyasaka N, Nanki T.
    • Journal Title

      Mod.Rheumatol. 20

      Pages: 244-244

    • NAID

      10027169254

    • Data Source
      KAKENHI-PROJECT-20591166
  • [Journal Article] Pathogenic role of CXCR7 in rheumatoid arthritis.2010

    • Author(s)
      Watanabe K, Penfold MET, Matsuda A, Ohyanagi N, Kaneko K, Miyabe Y, Matsumoto K, Schall TJ, Miyasaka N, Nanki T.
    • Journal Title

      Arthritis Rheum. 62

      Pages: 3211-3211

    • Data Source
      KAKENHI-PROJECT-20591166
  • [Journal Article] Hypoxia-induced abrogation of contact-dependent inhibition of rheumatoid arthritis synovial fibroblast proliferation.2009

    • Author(s)
      Nonomura Y, Mizoguchi F, Suzuki A, Nanki T, Kato H, Miyasaka N, Kohsaka H.
    • Journal Title

      J.Rheumatol. 36

      Pages: 698-698

    • Data Source
      KAKENHI-PROJECT-20591166
  • [Journal Article] Retinoid ameliorates experimental autoimmune myositis, with modulation of Th cell differentiation and antibody production in vivo.2009

    • Author(s)
      Ohyanagi N, Ishido M, Suzuki F, Kaneko K, Kubota T, Miyasaka N, Nanki T.
    • Journal Title

      Arthritis Rheum. 60

      Pages: 3118-3118

    • Data Source
      KAKENHI-PROJECT-20591166
  • [Journal Article] Alterations in peripheral blood memory B cells in patients with active rheumatoid arthritis are dependent on the action of tumour necrosis factor.2009

    • Author(s)
      Souto-Carneiro MM, Mahadevan V, Takada K, Fritsch-Stork R, Nanki T, Brown M, Fleisher TA, Wilson M, Goldbach-Mansky R, Lipsky PE.
    • Journal Title

      Arthritis Res.Ther. 11

    • Data Source
      KAKENHI-PROJECT-20591166
  • [Journal Article] Chemokine receptor expression and functional effects of chemokines on B cells : Implication in the pathogenesis of rheumatoid arthritis.2009

    • Author(s)
      Toshihiro Nanki, et al
    • Journal Title

      Arthritis Res.Ther. 11

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591166
  • [Journal Article] Possible involvement of chemokine-induced platelet activation in thrombophilic diathesis of antiphospholipid syndrome: an attractive target for the NF-kB-specific inhibitor DHMEQ.2009

    • Author(s)
      Kubota T, Fukuya Y, Hashimoto R, Kanda T, Suzuki H, Okamura Y, Nanki T, Miyasaka N, Umezawa K.
    • Journal Title

      Ann.N.Y.Acad.Sci. 1173

      Pages: 137-145

    • Data Source
      KAKENHI-PROJECT-20591166
  • [Journal Article] Chemokine receptor expression and functional effects of chemokines on B cells: Implication in the pathogenesis of rheumatoid arthritis.2009

    • Author(s)
      Nanki T, Takada K, Komano Y, Morio T, Kanegane H, Nakajima A, Lipsky PE, Miyasaka N.
    • Journal Title

      Arthritis Res.Ther. 11

    • Data Source
      KAKENHI-PROJECT-20591166
  • [Journal Article] Reevaluation of antibody titers 1 year after influenza vaccination in patients with rheumatoid arthritis receiving TNF blockers. 2008 Nov 18.2008

    • Author(s)
      Nii T, Kubota T, Nanki T, Komano Y, Harigai M, et al.
    • Journal Title

      Modern Rheumatology (On linefirst)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390158
  • [Journal Article] SDF-1 synergistically enhances IL-3-induced activation of the Raf-1/MEK/Erk signaling pathway through activation of Rac and its effector Pak kinases to promote hematopoiesis and chemotaxis.2005

    • Author(s)
      Ayako Arai, Aishun Jin, Weihua Yan, Daisuke Mizuchi, Koh Yamamoto, Toshihiro Nanki, Osamu Miura
    • Journal Title

      Cell.Signal. 17(4)

      Pages: 497-506

    • Data Source
      KAKENHI-PROJECT-15790510
  • [Journal Article] Development of TCRB CDR3 length repertoire of human T lymphocytes.2004

    • Author(s)
      Junko Nishio, Mihoko Suzuki, Toshihiro Nanki, Nobuyuki Miyasaka, Hitoshi Kohsaka
    • Journal Title

      Int.Immunol. 16(3)

      Pages: 423-431

    • NAID

      10013084180

    • Data Source
      KAKENHI-PROJECT-15790510
  • [Journal Article] Differential expression of matrix metalloproteinases and cyclooxygenases in synovial cells exposed to Borrelia burgdorferi.2004

    • Author(s)
      Sunit K.Singh, Henner Morbach, Toshihiro Nanki, Claudius Faber, Verena Baar, Hermann J.Girschick
    • Journal Title

      Inflamm.Res. 53(12)

      Pages: 689-696

    • Data Source
      KAKENHI-PROJECT-15790510
  • [Journal Article] Inhibition of fractalkine ameliorates murine collagen-induced arthritis.2004

    • Author(s)
      Nanki T, Urasaki Y, Imai T, Nishimura M, Muramoto K, Kubota T, Miyasaka N
    • Journal Title

      J.Immunol. 173(11)

      Pages: 7010-7016

    • Data Source
      KAKENHI-PROJECT-15659235
  • [Journal Article] Inhibition of fractalkine ameliorates murine collagen-induced arthritis.2004

    • Author(s)
      Toshihiro Nanki, Yasuyo Urasaki, Toshio Imai, Miyuki Nishimura, Kenzo Muramoto, Tetsuo Kubota, Nobuyuki Miyasaka
    • Journal Title

      J.Immunol. 173(11)

      Pages: 7010-7016

    • Data Source
      KAKENHI-PROJECT-15790510
  • [Journal Article] Development of TCRB CDR3 length repertoire of human T lymphocytes.2004

    • Author(s)
      Nishio J, Suzuki M, Nanki T, Miyasaka N, Kohsaka H
    • Journal Title

      Int.Immunol. 16(3)

      Pages: 423-431

    • NAID

      10013084180

    • Data Source
      KAKENHI-PROJECT-15659235
  • [Journal Article] Methotrexate and trimethoprim-sulfamethoxazole use for PCP prophylaxis.

    • Author(s)
      Yamazaki H, Nanki T, Miyasaka N, Harigai, M.
    • Journal Title

      J Rheumatol in press.

    • Data Source
      KAKENHI-PROJECT-20390158
  • [Journal Article] Incidence and risk factors for serious infection in rheumatoid arthritis patients treated with tumor necrosis factor (TNF) inhibitors ; a report from the Registry of Japanese Rheumatoid Arthritis Patients for Long-Term Safety (REAL).

    • Author(s)
      Komano Y, Tanaka M, Nanki T, et al.
    • Journal Title

      J Rheumatol(24人中24番目) in press.

    • Data Source
      KAKENHI-PROJECT-20390158
  • [Presentation] 間質性肺炎における細胞老化機構の関与2022

    • Author(s)
      山田 善登、西尾 純子、南木敏宏
    • Organizer
      第66回日本リウマチ学会総会
    • Data Source
      KAKENHI-PROJECT-21K08482
  • [Presentation] 間質性肺炎における細胞老化機構の関与2021

    • Author(s)
      山田 善登、本村 香織、西尾 純子、南木敏宏
    • Organizer
      第8回JCRベーシックリサーチカンファレンス
    • Data Source
      KAKENHI-PROJECT-21K08482
  • [Presentation] 肺胞細菌叢が関与する間質性肺炎の病態の研究2021

    • Author(s)
      山田 善登、水谷 聡、佐藤 洋志、村岡 成、西尾 純子、南木敏宏
    • Organizer
      第65回日本リウマチ学会総会
    • Data Source
      KAKENHI-PROJECT-21K08482
  • [Presentation] Fractalkine promotes differentiation into osteoclasts from human peripheral blood monocytes.2019

    • Author(s)
      Sei Muraoka, Kaichi Kaneko, Natsuko Kusunoki, Shinichi Kawai, Toshihiro Nanki
    • Organizer
      ヨーロッパリウマチ学会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09987
  • [Presentation] フラクタルカインによるヒト末梢血単球からの破骨細胞分化誘導亢進2018

    • Author(s)
      村岡成、金子開知、楠夏子、山田壯一、佐藤洋志、川合眞一、南木 敏宏
    • Organizer
      第62回日本リウマチ学会総会・学術総会
    • Data Source
      KAKENHI-PROJECT-17K09987
  • [Presentation] フラクタルカインによるヒト末梢血単球からの破骨細胞分化誘導亢進2018

    • Author(s)
      村岡成、金子開知、楠夏子、山田壯一、佐藤洋志、川合眞一、南木 敏宏
    • Organizer
      第62回日本リウマチ学会総会
    • Data Source
      KAKENHI-PROJECT-17K09987
  • [Presentation] 膠原病における免疫抑制療法下の肺感染症に関する前向き研究2013

    • Author(s)
      山崎隼人、酒井良子、小池竜司、田中みち、南木敏宏、渡部香織、宮坂信之、針谷正祥
    • Organizer
      第57回日本リウマチ学会総会・学術集会
    • Place of Presentation
      京都(国立京都国際会館)
    • Data Source
      KAKENHI-PROJECT-23590171
  • [Presentation] リゾフォスファチジン酸受容体1(LPA_1)欠損による関節炎抑制2013

    • Author(s)
      宮部斉重、宮部千恵、福田真、横山和佳、宮坂信之、南木敏宏
    • Organizer
      第57回日本リウマチ学会総会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23591435
  • [Presentation] Leucine-rich alpha-2 glycoprotein is a potential disease acitivity marker under IL-6 suppression in autoimmune arthritis2013

    • Author(s)
      Honda H, Serada S, Fujimoto M, Hattori K, Ogata A, Nanki T, Takeuchi T, Naka T
    • Organizer
      ヨーロッパリウマチ学会
    • Place of Presentation
      マドリード
    • Data Source
      KAKENHI-PROJECT-23591435
  • [Presentation] Lysophosphatidic acid receptor LPA_1 is essential for development of arthritis2013

    • Author(s)
      Miyabe Y, Miyabe C, Iwai Y, Takayasu A, Fukuda S, Yokoyama W, Nagai J, Jona M, Tokuhara Y, Ohkawa R, Albers HM, Ovaa H, Aoki J, Chun J, Yatomi Y, Ueda H, Miyasaka M, Miyasaka N, Nanki T
    • Organizer
      ヨーロッパリウマチ学会
    • Place of Presentation
      マドリード
    • Data Source
      KAKENHI-PROJECT-23591435
  • [Presentation] Am80によるCandida albicans water-soluble fraction誘導血管炎の抑制効果2012

    • Author(s)
      宮部千恵、宮部斉重、大野尚仁、高橋啓、宮坂信之、南木敏宏
    • Organizer
      第56回日本リウマチ学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591435
  • [Presentation] CCL18による関節リウマチ線維芽細胞様滑膜細胞の活性化2012

    • Author(s)
      髙安愛子、宮部斉重、金子佳代子、宮部千恵、横山和佳、福田真、窪田哲朗、宮坂信之、南木敏宏
    • Organizer
      第56回日本リウマチ学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591435
  • [Presentation] Anti-IL-6 autoantibody inhibited elevation of serum C-reactive protein level in two patients with severe bacterial infection2012

    • Author(s)
      Nanki T, Onoue I, Nagasaka K, Hirata S, Hosoya T, Ebisawa M, Sugihara T, Harigai M, Miyasaka N
    • Organizer
      ヨーロッパリウマチ学会
    • Place of Presentation
      ベルリン
    • Data Source
      KAKENHI-PROJECT-23591435
  • [Presentation] Autotaxin and Lysophosphatidic Acid Receptors : Potential Target Molecules in New Therapies for Rheumatoid Arthritis2012

    • Author(s)
      Miyabe Y, Miyabe C, Iwai Y, Ebisawa M, Miyasaka M, Miyasaka N, Nanki T
    • Organizer
      Keystone Symposia, Chemokines and Leukocyte Trafficking in Homeostasis and Inflammation
    • Place of Presentation
      Breckenridge, USA
    • Data Source
      KAKENHI-PROJECT-23591435
  • [Presentation] カンナビノイドによる関節炎抑制作用2012

    • Author(s)
      福田真、高安愛子、横山和佳、宮部千恵、宮部斉重、宮坂信之、南木敏宏
    • Organizer
      第56回日本リウマチ学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591435
  • [Presentation] 関節リウマチの病態形成におけるCCL25/CCR9相互作用の関与2012

    • Author(s)
      横山和佳、金子佳代子、高安愛子、福田真、宮部斉重、宮部千恵、宮坂信之、南木敏宏
    • Organizer
      第56回日本リウマチ学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591435
  • [Presentation] Am80, a retinoic acid receptor agonist, ameliorates murine vasculitis through the suppression of neutrophil migration and activation2012

    • Author(s)
      Miyabe C, Miyabe Y, Miura N, Takahashi K, Terashima Y, Toda E, Honda F, Morio T, Yamagata N, Ohno N, Shudo K, Suzuki J, Isobe M, Matsushima K, Tsuboi R, Miyasaka N, Nanki T
    • Organizer
      第76回アメリカリウマチ学会
    • Place of Presentation
      ワシントンDC
    • Data Source
      KAKENHI-PROJECT-23591435
  • [Presentation] オートタキシン/リゾフォスファチジン酸受容体を標的とした関節リウマチの新規治療法開発2012

    • Author(s)
      宮部斉重、宮部千恵、高安愛子、福田真、横山和佳、宮坂信之、南木敏宏
    • Organizer
      第56回日本リウマチ学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591435
  • [Presentation] Am80 ameliorates murine model of vasculitis via suppression of neutrophil and endothelial cell activation2012

    • Author(s)
      Miyabe C, Miyabe Y, Miura NN, Takahashi K, Terashima Y, Morio T, Ohno N, Shudo K, Yamagata N, Suzuki K, Suzuki J, Matsushima K, Tsuboi R, Miyasaka N, Nanki T
    • Organizer
      The Asia Pacific Meeting of Vasculitis and ANCA Workshop
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591435
  • [Presentation] アダリムマブ使用関節リウマチ患者におけるニューモシスチス肺炎2011

    • Author(s)
      渡部香織、小池竜司、酒井良子、田中みち、山崎隼人、駒野有希子、南木敏宏、宮坂信之、針谷正祥
    • Organizer
      第39回日本臨床免疫学会
    • Place of Presentation
      東京都
    • Data Source
      KAKENHI-PROJECT-23590171
  • [Presentation] リゾフォスファチジン酸を標的とした関節リウマチの新規治療法開発2011

    • Author(s)
      宮部斉重、福田真、金子佳代子、宮坂信之、南木敏宏
    • Organizer
      第55回日本リウマチ学会総会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-23591435
  • [Presentation] オートタキシン、リゾフォスファチジン酸受容体を標的とした関節リウマチの新規治療法開発2011

    • Author(s)
      宮部斉重、宮部千恵、岩井佳子、海老澤昌史、宮坂昌之、宮坂信之、南木敏宏
    • Organizer
      第40回日本免疫学会総会
    • Place of Presentation
      千葉
    • Data Source
      KAKENHI-PROJECT-23591435
  • [Presentation] 合成レチノイドAm80はCandida albicans water-soluble fraction誘導血管炎を抑制する2011

    • Author(s)
      宮部千恵、宮部斉重、三浦典子、高橋啓、寺島裕也、大野尚仁、森尾友宏、松島綱治、宮坂信之、南木敏宏
    • Organizer
      第40回日本免疫学会総会
    • Place of Presentation
      千葉
    • Data Source
      KAKENHI-PROJECT-23591435
  • [Presentation] Chemerin Activates Fibroblast-like Synoviocytes in Patients with Rheumatoid Arthritis2011

    • Author(s)
      Kaneko K, Miyabe Y, Takayasu A, Fukuda S, Miyabe C, Ebisawa M, Yokoyama W, Watanabe K, Imai T, Muramoto K, Terashima Y, Sugihara T, Matsushima K, Miyasaka N, Nanki T
    • Organizer
      第75回アメリカリウマチ学会
    • Place of Presentation
      シカゴ
    • Data Source
      KAKENHI-PROJECT-23591435
  • [Presentation] Chemerin and ChemR23 Expression in Rheumatoid Arthritis:The Therapeutic Implication of the Pathway.2010

    • Author(s)
      金子佳代子, 渡部香織, 宮坂信之, 南木敏宏
    • Organizer
      第14回国際免疫学会
    • Data Source
      KAKENHI-PROJECT-20591166
  • [Presentation] 関節リウマチの病態形成におけるCXCR7 の役割に ついて2009

    • Author(s)
      渡部香織, 南木敏宏, 金子佳代子, 宮坂信之
    • Organizer
      第53回日本リウマチ学会総会
    • Data Source
      KAKENHI-PROJECT-20591166
  • [Presentation] シンポジウム1「膠原病の新展開」PM/DM2009

    • Author(s)
      南木敏宏
    • Organizer
      第20回日本リウマチ学会関東支部学術集会
    • Data Source
      KAKENHI-PROJECT-20591166
  • [Presentation] Retinoid ameliorates collagen-induced arthritis with modulating Th cell development and antibody production.Keystone symposia2009

    • Author(s)
      Nanki T, Sato A, Watanabe K, Kaneko K, Ishido M, Miyasaka N
    • Organizer
      TH17 Cells in Health and Disease.
    • Data Source
      KAKENHI-PROJECT-20591166
  • [Presentation] Pathogenic Role of CXCR7 in Rheumatoid Arthritis.2009

    • Author(s)
      Watanabe K, Nanki T, Kaneko K, Schall TJ, Miyasaka N
    • Organizer
      第9回国際炎症学会
    • Data Source
      KAKENHI-PROJECT-20591166
  • [Presentation] 多発性筋炎/皮膚筋炎におけるCX3CL1 (fractalkine) 発現の解析2009

    • Author(s)
      鈴木文仁、南木敏宏、今井俊夫、廣畑俊成、宮坂信之
    • Organizer
      第53回日本リウマチ学会総会
    • Data Source
      KAKENHI-PROJECT-20591166
  • [Presentation] The Effect of Synthetic Retinoid, Am80, On T Helper Cell Development and Antibody Production in Murine Collagen-Induced Arthritis.2009

    • Author(s)
      Nanki T, Sato A, Watanabe K, Kaneko K, Murakami Y, Ishido M, Miyasaka N
    • Organizer
      第73回アメリカリウマチ学会
    • Data Source
      KAKENHI-PROJECT-20591166
  • [Presentation] Chemerin and ChemR23 expression in rheumatoid arthritis: the therapeutic implication of the pathway.2009

    • Author(s)
      金子佳代子, 渡部香織, 宮坂信之, 南木敏宏
    • Organizer
      第3 回日本免疫学会総会
    • Data Source
      KAKENHI-PROJECT-20591166
  • [Presentation] Arthritic Joint-Targeting siRNA/Wrapsome? as a Treatment Strategy for Rheumatoid Arthritis.2009

    • Author(s)
      駒野有希子, 八木信宏, 尾上育美, 金子佳代子, 宮坂信之, 南木敏宏
    • Organizer
      第73回アメリカリウマチ学会
    • Data Source
      KAKENHI-PROJECT-20591166
  • [Presentation] siRNA/WrapsomeR を 用いた関節リウマチに対する新規治療法の開発2009

    • Author(s)
      駒野有希子、八木信宏、尾上育美、金子佳代子、宮坂信之、南木敏宏
    • Organizer
      第37回日本臨床免疫学会
    • Data Source
      KAKENHI-PROJECT-20591166
  • [Presentation] The effect of synthetic retinoid, Am80, on T helper cell development and antibody production in murine collagen-induced arthritis.2009

    • Author(s)
      Sato A, Watanabe K, Kaneko K, Murakami Y, Miyasaka N, Nanki T
    • Organizer
      第39回日本免疫学会総会
    • Data Source
      KAKENHI-PROJECT-20591166
  • [Presentation] siRNA/wrapped liposome複合体を用いた関節リウマチに対する新規治療法の開発2009

    • Author(s)
      駒野有希子、南木敏宏、八木信宏、尾上育美、金子佳代子、宮坂信之
    • Organizer
      第53回日本リウマチ学会総会
    • Data Source
      KAKENHI-PROJECT-20591166
  • [Presentation] Pathogenic Role of CXCR7 in Rheumatoid Arthritis.2008

    • Author(s)
      Watanabe K, Nanki T, Penfold ME, Ohyanagi N, Kaneko K, Matsuda A, Matsumoto K, Miyasaka N
    • Organizer
      第72回アメリカリウマチ学会
    • Data Source
      KAKENHI-PROJECT-20591166
  • [Presentation] 実験的多発性筋炎に対するレチノイド、Am80 の効果の検討2008

    • Author(s)
      南木敏宏、大柳菜歩、石堂美和子、窪田哲朗、宮坂信之
    • Organizer
      第52回日本リウマチ学会総会
    • Data Source
      KAKENHI-PROJECT-20591166
  • [Presentation] 抗リン脂質抗体症候群の向血栓傾向におけるケモカインの作用に関する検討2008

    • Author(s)
      窪田哲朗、福谷泰子、南木敏宏、宮坂信之
    • Organizer
      第52回日本リウマチ学会総会
    • Data Source
      KAKENHI-PROJECT-20591166
  • [Presentation] Pathogenic Role of CXCR7 in Rheumatoid Arthritis.2008

    • Author(s)
      Watanabe K, Nanki T, Penfold ME, Kaneko K, Matsuda A, Matsumoto K, Miyasaka N
    • Organizer
      第38回日本免疫学会総会
    • Data Source
      KAKENHI-PROJECT-20591166
  • [Presentation] 膠原病における免疫抑制療法下の肺感染症に関する研究

    • Author(s)
      山崎隼人、酒井良子、小池竜司、田中みち、南木敏宏、渡部香織、宮坂信之、針谷正祥
    • Organizer
      リウマチヤングアカデミー
    • Place of Presentation
      北広島クラッセホテル
    • Data Source
      KAKENHI-PROJECT-23590171
  • [Presentation] カンナビノイドによる関節炎抑制作用

    • Author(s)
      福田真、高安愛子、横山和佳、宮部千恵、宮部斉重、宮坂信之、南木敏宏
    • Organizer
      日本リウマチ学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591435
  • 1.  MIYASAKA Nobuyuki (30157622)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 51 results
  • 2.  HARIGAI Masayoshi (20238207)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 6 results
  • 3.  Hajime Kono (60585074)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  関根 知世子 (40392005)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 5.  KOIKE Ryuji (50250220)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 6.  ATSUMI Tatsuya (20301905)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  TAKENO Mitsuhiro (50236494)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  KAMEDA Hideto (00265795)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  SAITO Kazuyoshi (30279327)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  FUJII Takao (70255462)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  TSUTANI Kiichiro (80142040)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  SAWADA Tetsuji (50235470)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  TAMURA Naoto (20227284)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  TOHMA Shigeto (50207528)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  KAWAKAMI Atsushi (90325639)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  HAYASHI Taichi (00466674)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  NAKAMURA Takahiro (60415255)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  TANAKA Michi (50277141)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 19.  Sugihara Takahiko (00716441)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  伊藤 聡 (00334681)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  石崎 達郎 (30246045)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  石神 昭人 (50270658)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  田中 雅嗣 (60155166)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  楠 夏子 (10328924)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 25.  西尾 純子 (40598679)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 26.  SEKI Reiko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  YANAGIDA Tamiko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  森尾 友宏
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 29.  平田 真哉
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 30.  宮坂 昌之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 31.  広畑 俊成
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 32.  永井 潤
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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