Miyake Masaki 三宅正紀

… Alternative Names

三宅正紀ミヤケマサキ

MIYAKE Masaki 三宅正紀

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Researcher Number	00295560
Other IDs
Affiliation (Current)	2025: 奥羽大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2019 – 2021: 静岡県立大学, 薬学部, 講師 2011 – 2012: 静岡県立大学, 薬学部, 講師 2010: 静岡県立大学, 薬学部 2005: 静岡県立大学, 薬学部, 講師 2004: 静岡県立大学, 講師 2000 – 2003: University of Shizuoka, Microbiology, Assistant Professor, 薬学部, 講師 1998 – 1999: University of Shizuoka, Microbiology, Research Associate, 薬学部, 助手
Review Section/Research Field	Principal Investigator Bacteriology (including Mycology) / Basic Section 49050:Bacteriology-related Except Principal Investigator Bacteriology (including Mycology)
Keywords	Principal Investigator 病原性 / レジオネラ / エスケープ / 脂肪滴 / 動脈硬化症 / Helicobacter cinaedi / CAIP / 細胞質へエスケープ / ファゴソーム / Ⅵ型分泌装置 … More / 細胞内生残性 / マクロファージ / 再燃 / ヘリコバクター・シネディ / 細胞毒性 / 細胞内増殖 / 細菌 / 機能未知遺伝子 / Toxh変異株 / マウス病原性 / アポトーシス / 強細胞毒性 / 宿主細胞内増殖 / Legionella pneumophila / MS / MALDI-TOF / 2-D DIGE / 仮想蛋白質 / 細胞内寄生 / 病原因子 / MALDI-TOF MS / 2-DDIGE / プロテオミクス / 増殖相 … More Except Principal Investigator Borrelia burgdorferi / Borrelia / Lyme disease / ボレリア / ライム病 / Ixodes / GAPDH / Ixodid tick / Borrelia valaisiana / Borrelia garinii / Borrelia afzelii / マダニ / Galactosylceramide / ガラクトシルセラミド / スフィンゴ糖脂質 / Turkey / Russia / Lyme borreliosis / トルコ / ロシア / ライムボレリア症 / Vaccine / glycosphingolipid / Adhesion / ワクチン / 細胞接着 / Systematic classification / 系統分類 / Glyceradehyde-3-phosphate dehydrogenase / Glycosphingolipid / Adhesion molecule / Virulence factor / グリセルアルデヒド-3ーリン酸脱水素酵素 / カラクトシルセラミド / グリセルアルデヒド-3-リン酸脱水素酵素 / 接着因子 / 病原因子 Less

Study of pathogenic mechanisms of <i>Helicobacter cinaedi</i> focused on its tropism for macrophages.Principal Investigator
- Principal Investigator
  
  Miyake Masaki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  University of Shizuoka
The clarification of mechanisms for cytotoxic effect of Legionella hyper-toxic mutants which are intracellular growth-deficient (Toxh mutants) on host cells.Principal Investigator
- Principal Investigator
  
  MIYAKE Masaki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  University of Shizuoka
プロテオミクスによるレジオネラ感染制御因子の網羅的解析Principal Investigator
- Principal Investigator
  
  三宅正紀
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  University of Shizuoka
Distribution and transmission of Borrelia burgdorferi sensu lato in Eurasia and control of Lyme borreliosis.
- Principal Investigator
  
  MASUZAWA Toshiyuki
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  University of Shizuoka
Glycosphingolipid binding protein (Gbp) of Lyme disease Borrelia, Its function and vaccine development.
- Principal Investigator
  
  MASUZAWA Toshiyuki
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  University of Shizuoka
Molecular epidemiology of Borrelia burgdorferi sensu lato in the East Asia.
- Principal Investigator
  
  MASUZAWA Toshiyuki
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  University of Shizuoka
Adhesion Molecule of Borrelia burgdorferi ; Its Function and Application
- Principal Investigator
  
  MASUZAWA Toshiyuki
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  University of Shizuoka

All 2021 2020 2019 2013 2012 2011 2010 2005 Other

All Journal Article Presentation

[Journal Article] Ciliates expel environmental Legionella-laden pellets to stockpile food.2012
- Author(s)
  Fuhito Hojo, Daisuke Sato, Junji Matsuo, Masaki Miyake, Shinji Nakamura, Miyuki Kunichika, Yasuhiro Hayashi, Mitsutaka Yoshida, Kaori Takahashi, Hiromu Takemura, Shigeru Kamiya and Hiroyuki Yamaguchi
- Journal Title
  
  Appl. Environ. Microbiol.
  
  Volume: 78 Issue: 15 Pages: 5247-5257
- DOI
  10.1128/aem.00421-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590398, KAKENHI-PROJECT-23590518, KAKENHI-PROJECT-24659194, KAKENHI-PUBLICLY-24117501
[Journal Article] Phagocytic Entry of <i>Legionella pneumophila</i> into Macrophages through Phosphatidylinositol 3,4,5-Trisphosphate-Independent Pathway2012
- Author(s)
  Toshihiko Harada, Takashi Tanikawa, Yasunori Iwasaki, Masao Yamada, Yasuyuki Imai, Masaki Miyake
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 35 Issue: 9 Pages: 1460-1468
- DOI
  10.1248/bpb.b11-00011
- NAID
  130001872062
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Data Source
  KAKENHI-PROJECT-22590398
[Journal Article] Proteomic analysis of growth phase-dependent expression of Legionella pneumophila proteins which involves regulation of bacterial virulence traits.2010
- Author(s)
  Tsuyoshi Hayashi, Masahiro Nakamichi, Hirotaka Naitou, Norio Ohashi, Yasuyuki Imai, Masaki Miyake
- Journal Title
  
  PLoS One
  
  Volume: 5 Issue: 7 Pages: e11718-e11718
- DOI
  10.1371/journal.pone.0011718
- Data Source
  KAKENHI-PROJECT-22590398
[Journal Article] Characterization of Legionella pneumophila pmiA, a gene essential for infectivity of protozoa and macrophages2005
- Author(s)
  Masaki Miyake
- Journal Title
  
  Infection and Immunity 73・10
  
  Pages: 6272-6282
- Data Source
  KAKENHI-PROJECT-16790258
[Presentation] レジオネラシトクロームc成熟化遺伝子群ccmの変異は、レジオネラ小胞への鉄輸送を担うエフェクターLPW_30711の宿主内発現を低下させる2021
- Author(s)
  三宅正紀
- Organizer
  USフォーラム 2021
- Data Source
  KAKENHI-PROJECT-19K07559
[Presentation] Helicobacter cinaediの感染マクロファージにおける部分的細胞内生残性に導く特異的細胞内動態の解析2020
- Author(s)
  三宅天地人、三宅正紀、山口美幸、前田久美子、小野内拓也、河村好章、今井康之
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-19K07559
[Presentation] 新興感染症病原体ヘリコバクター・シネディのマクロファージ内における部分的細胞内生残性に導く特異的細胞内動態の解析2020
- Author(s)
  三宅正紀
- Organizer
  USフォーラム2020
- Data Source
  KAKENHI-PROJECT-19K07559
[Presentation] Specific behavior of Helicobacter cinaedi during macrophage infection for partial intracellular survival2019
- Author(s)
  Amon Miyake, Masaki Miyake, Miyuki Yamaguchi, Tetsuya Furukawa, Takuya Onouchi, Kumiko Maeda, Yasuyuki Imai
- Organizer
  第24回静岡健康・長寿学術フォーラム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07559
[Presentation] 新興感染症菌ヘリコバクター・シネディのヒトマクロファージ感染における細胞内動態の解析2019
- Author(s)
  三宅正紀、河村好章、今井康之
- Organizer
  USフォーラム2019
- Data Source
  KAKENHI-PROJECT-19K07559
[Presentation] 茶カテキン類のレジオネラに対する殺菌・増殖抑制作用2013
- Author(s)
  三宅正紀
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590398
[Presentation] 茶カテキン類のレジオネラに対する殺菌・増殖抑制作用2013
- Author(s)
  三宅正紀、山田雅音、東真結実、閔俊哲、今井康之
- Organizer
  日本薬学会第133 年会
- Place of Presentation
  横浜
- Year and Date
  2013-03-30
- Data Source
  KAKENHI-PROJECT-22590398
[Presentation] 茶カテキンのレジオネラに対する殺菌・増殖抑制効果の検証2012
- Author(s)
  山田雅音、今井康之、三宅正紀
- Organizer
  第85回日本細菌学会総会
- Place of Presentation
  長崎
- Year and Date
  2012-03-28
- Data Source
  KAKENHI-PROJECT-22590398
[Presentation] 宿主細胞内増殖性を欠損したレジオネラ強細胞毒性変異株 (Toxh 変異株) の性状解析2012
- Author(s)
  三宅正紀
- Organizer
  US フォーラム 2012
- Place of Presentation
  静岡
- Year and Date
  2012-09-25
- Data Source
  KAKENHI-PROJECT-22590398
[Presentation] 活性酸素産生系の活性化を伴わないLegionella pneumpphilaのマクロファージ侵入について2012
- Author(s)
  三宅正紀
- Organizer
  第24回微生物シンポジウム
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22590398
[Presentation] 活性酸素産生系の活性化を伴わないLegionella pneumpphila のマクロファージ侵入について2012
- Author(s)
  三宅正紀、原田俊彦、岩崎泰憲、山田雅音、今井康之
- Organizer
  第24回微生物シンポジウム
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22590398
[Presentation] 茶カテキン類のレジオネラ感染成立に及ぼす影響及び感染阻害剤としての有用性に関する研究2012
- Author(s)
  三宅正紀
- Organizer
  US フォーラム 2012
- Place of Presentation
  静岡
- Year and Date
  2012-09-25
- Data Source
  KAKENHI-PROJECT-22590398
[Presentation] レジオネラのIV 型分泌系の機能に影響する新規遺伝子の同定2012
- Author(s)
  若井翔平、三宅正紀、小田祐一、Yousef Abu Kwaik、今井康之
- Organizer
  日本病院薬剤師会東海ブロック日本薬学会東海支部合同学術大会2012
- Place of Presentation
  岐阜
- Year and Date
  2012-11-18
- Data Source
  KAKENHI-PROJECT-22590398
[Presentation] 繊毛虫が放出する環境レジオネラを包含した小胞ペレットは繊毛虫の生存を支える備蓄栄養源として機能している2012
- Author(s)
  北条史、佐藤大祐、三宅正紀、松尾淳司、中村眞二、神谷茂、山口博之
- Organizer
  第79回日本細菌学会北海道支部学術総会
- Place of Presentation
  帯広
- Data Source
  KAKENHI-PROJECT-22590398
[Presentation] Characterization of Legionella hyper-toxic mutants which are intracellular growth-deficient (Tox^h mutants) for infectivity to host cells2011
- Author(s)
  Masaki Miyake
- Organizer
  International Union of Microbiological Societies 2011 Congress (IUMS 2011)
- Place of Presentation
  Sapporo, Japan
- Year and Date
  2011-09-07
- Data Source
  KAKENHI-PROJECT-22590398
[Presentation] レジオネラの宿主内増殖に関与する菌体タンパク質PmiAの機能解明2011
- Author(s)
  三宅正紀
- Organizer
  平成23年度中部乳酸菌研究会
- Place of Presentation
  新潟
- Year and Date
  2011-11-25
- Data Source
  KAKENHI-PROJECT-22590398
[Presentation] Characterization of Legionella hyper-toxic mutants which are intracellular growth-deficient (Toxh mutants) for infectivity to host cells.2011
- Author(s)
  Masaki Miyake, Ippei Yoshida, Minami Yamamoto, Ayumi Sugiyama, Yoshihiro Akimoto, Hayato Kawakami, Yousef Abu Kwaik, Yasuyuki Imai
- Organizer
  International Union of Microbiological Societies 2011 Congress (IUMS 2011)
- Place of Presentation
  Sapporo、Japan
- Year and Date
  2011-09-07
- Data Source
  KAKENHI-PROJECT-22590398
[Presentation] IV 型分泌装置Icm/dot コード領域以外の変異により宿主内へのエフェクター送達が阻害されるレジオネラ細胞内増殖性欠損株について2011
- Author(s)
  小田祐一、若井翔平、Yousef Abu Kwaik、今井康之、三宅正紀
- Organizer
  日本薬学会第131 年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-22590398
[Presentation] レジオネラの病原性状の制御に関与する増殖相依存的タンパク質のプロテオーム解析2011
- Author(s)
  三宅正紀、林豪士、中道正浩、内藤博敬、大橋典男、今井康之
- Organizer
  日本薬学会第131 年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-22590398
[Presentation] レジオネラの宿主内増殖に関与する菌体タンパク質PmiA の機能解明2011
- Author(s)
  三宅正紀、今井康之
- Organizer
  平成23 年度中部乳酸菌研究会
- Place of Presentation
  新潟
- Year and Date
  2011-11-25
- Data Source
  KAKENHI-PROJECT-22590398
[Presentation] 細胞内増殖性を欠損したレジオネラ強細胞毒性株の性状解析2011
- Author(s)
  三宅正紀
- Organizer
  第23回微生物シンポジウム
- Place of Presentation
  銚子
- Year and Date
  2011-09-02
- Data Source
  KAKENHI-PROJECT-22590398
[Presentation] 茶カテキンのレジオネラ生存性及び増殖性に及ぼす影響2011
- Author(s)
  山田雅音、東真結実、三宅正紀、今井康之
- Organizer
  日本病院薬剤師会東海ブロック日本薬学会東海支部合同学術大会2011
- Place of Presentation
  名古屋
- Year and Date
  2011-11-23
- Data Source
  KAKENHI-PROJECT-22590398
[Presentation] 細胞内増殖性を欠損したレジオネラ強細胞毒性株の性状解析2010
- Author(s)
  三宅正紀、吉田一平、山本みな実、杉山亜由美、秋元義弘、川上速人、Yousef Abu Kwaik、今井康之
- Organizer
  第23回微生物シンポジウム
- Place of Presentation
  銚子
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-22590398
[Presentation] レジオネラ膜タンパク質PmiA はIV型分泌装置Icm/Dot 構成因子DotA の安定化を担う2010
- Author(s)
  三宅正紀、岩崎泰憲、林豪士、Yousef Abu Kwaik、今井康之
- Organizer
  第22回微生物シンポジウム
- Place of Presentation
  大阪
- Year and Date
  2010-09-04
- Data Source
  KAKENHI-PROJECT-22590398
[Presentation] レジオネラ膜タンパク質PmiAはIV型分泌装置Icm/Dot構成因子DotAの安定化を担う2010
- Author(s)
  三宅正紀, 他
- Organizer
  第22回微生物シンポジウム
- Place of Presentation
  大阪
- Year and Date
  2010-09-04
- Data Source
  KAKENHI-PROJECT-22590398
[Presentation] 茶カテキン類のレジオネラ感染成立に及ぼす影響及び感染阻害剤としての有用性に関する研究
- Author(s)
  三宅正紀
- Organizer
  USフォーラム 2012
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-22590398
[Presentation] レジオネラのIV型分泌系の機能に影響する新規遺伝子の同定
- Author(s)
  三宅正紀
- Organizer
  日本病院薬剤師会東海ブロック日本薬学会東海支部合同学術大会2012
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-22590398

1. MASUZAWA Toshiyuki (10181645)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. YANAGIHARA Yasutake (30046255)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. TAKADA Nobuhiro (90003409)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. KAWABATA Masato (30175294)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KADOSAKA Teruki (90109760)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 趙敏基

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Miyake Masaki 三宅 正紀

三宅 正紀 ミヤケ マサキ

MIYAKE Masaki 三宅 正紀

Research Projects

Research Products

Co-Researchers

Study of pathogenic mechanisms of <i>Helicobacter cinaedi</i> focused on its tropism for macrophages.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The clarification of mechanisms for cytotoxic effect of Legionella hyper-toxic mutants which are intracellular growth-deficient (Toxh mutants) on host cells.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

プロテオミクスによるレジオネラ感染制御因子の網羅的解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Distribution and transmission of Borrelia burgdorferi sensu lato in Eurasia and control of Lyme borreliosis.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Glycosphingolipid binding protein (Gbp) of Lyme disease Borrelia, Its function and vaccine development.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular epidemiology of Borrelia burgdorferi sensu lato in the East Asia.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Adhesion Molecule of Borrelia burgdorferi ; Its Function and Application

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Ciliates expel environmental Legionella-laden pellets to stockpile food.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Phagocytic Entry of <i>Legionella pneumophila</i> into Macrophages through Phosphatidylinositol 3,4,5-Trisphosphate-Independent Pathway2012

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Proteomic analysis of growth phase-dependent expression of Legionella pneumophila proteins which involves regulation of bacterial virulence traits.2010

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Characterization of Legionella pneumophila pmiA, a gene essential for infectivity of protozoa and macrophages2005

Author(s)

Journal Title

Data Source

[Presentation] レジオネラシトクロームc成熟化遺伝子群ccmの変異は、レジオネラ小胞への鉄輸送を担うエフェクターLPW_30711の宿主内発現を低下させる2021

Author(s)

Organizer

Data Source

[Presentation] Helicobacter cinaediの感染マクロファージにおける部分的細胞内生残性に導く特異的細胞内動態の解析2020

Author(s)

Organizer

Data Source

[Presentation] 新興感染症病原体ヘリコバクター・シネディのマクロファージ内における部分的細胞内生残性に導く特異的細胞内動態の解析2020

Author(s)

Miyake Masaki 三宅正紀

三宅正紀ミヤケマサキ

MIYAKE Masaki 三宅正紀