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OKA Naoki  岡 直樹

ORCIDConnect your ORCID iD *help
Researcher Number 00299421
Affiliation (based on the past Project Information) *help 2006: 久留米大学, 医学部, 講師
2003: 久留米大学, 医学部, 講師
1998 – 2002: 久留米大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Circulatory organs internal medicine / Circulatory organs internal medicine
Except Principal Investigator
Circulatory organs internal medicine
Keywords
Principal Investigator
LOXL / 遺伝子変異 / 心筋細胞 / フェニレフリン / 心筋肥大 / fibrosis / collagen / Lysyl oxydase / Cardiac Hypertrophy / トランスジェニックマウス … More / 心筋 / 活性酸素種 / 心肥大 / コラーゲン / 線維化 / Lysyl oxidase / maximum force / CaィイD12+ィエD1 sensitivity / muscle fiber / troponin T / mutation / cardiomyopathy / βミオシン重鎖 / 遺伝子導入 / 最大張力 / Ca^<2+>感受性 / スキンドファイバー / トロポニンT / 肥大型心筋症 / アポトーシス / 遺伝子異常 / 拡張型心筋症 / C / ラミンA / Gq / アデノウイルス / エンドセリン-1 / カベオリン-3 / ionomycin / 細胞内Ca^<2+> / α^1アドレナリン受容体 / カベオラ / カベオリン … More
Except Principal Investigator
cytokine / Adenylyl cyclase / β-adrenergic pathway / heart failure / IGF-1 / BNP / β-受容体リン酸化酵素 / アデニル酸シクラーゼ / β-受容体 / 交感神経 / 交感神経系 / サイトカイン / 心不全 / 荷電変化 / βミオシン重鎖 / トロポニンT / 遺伝子変異 / 肥大型心筋症 Less
  • Research Projects

    (7 results)
  • Research Products

    (11 results)
  • Co-Researchers

    (8 People)
  •  Functional analysis of LOXL-1 in the myocardiumPrincipal Investigator

    • Principal Investigator
      UEDA Tamenobu, 岡 直樹
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kurume University
  •  ラミンA/C遺伝子変異による拡張型心筋症発症機序の検討Principal Investigator

    • Principal Investigator
      岡 直樹
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kurume University
  •  心筋カベオリン-3の機能解析(カベオリン-3特異的阻害物質の開発)Principal Investigator

    • Principal Investigator
      岡 直樹
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kurume University
  •  肥大型心筋症の原因ならびに発症機序解明に関する分子遺伝学的研究

    • Principal Investigator
      中田 真詩
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kurume University
  •  心血管系におけるカベオリンの発現制御および機能に関する検討Principal Investigator

    • Principal Investigator
      岡 直樹
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kurume University
  •  Creation of a transgenic animal model of hypertrophic cardiomyopathy caused by cardiac troponin T mutation.Principal Investigator

    • Principal Investigator
      OKA Naoki, 中田 真詩
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kurume University
  •  Relationship between β-adrenergic signaling pathway and cytokines in hypertensive heart failure.

    • Principal Investigator
      IWAMI Gensho
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kurume University

All 2007 2006

All Journal Article Presentation Book

  • [Book] 肥大型心筋症ハンドブック、HCMの動物モデル2006

    • Author(s)
      岡 直樹, 大村治也, 今泉 勉
    • Total Pages
      317
    • Publisher
      日本医事新報社(東京)
    • Data Source
      KAKENHI-PROJECT-18590792
  • [Journal Article] Pulmonary Inflammation and Emphysema : Role of the Cytokines IL-18 and IL-132007

    • Author(s)
      Hoshino T, Oka N, et al.
    • Journal Title

      Am J Respir Crit Care Med. (Epub ahead of ptint)(In press)

    • Data Source
      KAKENHI-PROJECT-18590792
  • [Journal Article] Pulmonary inflammation and enphysema. Role of cytokines IL-18 and IL-13.2007

    • Author(s)
      Hoshino T, Kato S, Oka N, Imaoka H, Kinoshita T, Takei S, KitasatoY, Kawayama T, Imaizumi T, Yamada K, Young HA, Aizawa H
    • Journal Title

      Am JRespir Grit Care Med 176

      Pages: 49-62

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590792
  • [Journal Article] 心筋症.内科外来診療実践ガイド-縮刷版- 和田攻,大久保昭行,矢崎義雄,大内尉義編,文光堂,東京2006

    • Author(s)
      岡 直樹, 大村 治也, 今泉 勉
    • Journal Title

      内科外来診療実践ガイド 32

      Pages: 115-119

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590792
  • [Journal Article] Comparison of gene expression profiling in pressure and volume overload-induced myocardial hypertrophies in rats.2006

    • Author(s)
      Miyazaki H, Oka N, et al.
    • Journal Title

      Hypertens Res 29(12)

      Pages: 1029-1045

    • NAID

      10018560950

    • Data Source
      KAKENHI-PROJECT-18590792
  • [Journal Article] 肥大型心筋症の遺伝子異常と予後およびハイリスク症例の同定2006

    • Author(s)
      岡 直樹, 上田集宣, 今泉 勉
    • Journal Title

      Cardiac Practice 17(1)

      Pages: 35-39

    • Data Source
      KAKENHI-PROJECT-18590792
  • [Journal Article] Comparison of gene expression profiling in pressure and volume overload-induced myocardial hypertrophies in rats.2006

    • Author(s)
      Miyazaki H, Oka N, Koga A, Ohmura H, Ueda T, Imaizumi T
    • Journal Title

      Hypertens Res 29(12)

      Pages: 1029-1045

    • NAID

      10018560950

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590792
  • [Presentation] Roles of lysyl oxidase-like protein in heart.2007

    • Author(s)
      Ohmura H, Oka N, Miyazaki H, Ueda T, Imaizumi T
    • Organizer
      Japanese Circulation Society Meeting Scientific Session
    • Place of Presentation
      Kobe
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590792
  • [Presentation] Behavior and role of lysyl oxidase-like protein in development of cardiac hypertrophy.2006

    • Author(s)
      Ohmura H, Oka N, Miyazaki H, Ueda T, Imaizumi T
    • Organizer
      The 2nd China-Japan Cardiovascular Forum
    • Place of Presentation
      Beijin, China
    • Year and Date
      2006-11-04
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590792
  • [Presentation] Role of Caveolin-3 in cardiac hypertrophy.2006

    • Author(s)
      Oka N, Kikuchi T, Koga A, Ohmura H, Miyazaki H, Imaizumi T
    • Organizer
      The International symposium of Cardiology Frontiers Cardiomyopathy and Heart Failure
    • Place of Presentation
      Sapporo, Japan
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590792
  • [Presentation] Role of Caveolin-3 in cardiac hypertrophy2006

    • Author(s)
      Oka N, et. al.
    • Organizer
      The International symposium of Cardiology Frontiers:Cardiomyopathy and Heart Failure
    • Place of Presentation
      札幌
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590792
  • 1.  IWAMI Gensho (90203405)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 2.  中田 真詩 (70180304)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  KIKUCHI Toshio (20289432)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  UEDA Tamenobu (50389251)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 5.  西 宏文 (60189248)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  NAKAURA Hiroyuki (50279171)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  KOGA Akimasa (10309776)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 8.  MIYAZAKI Hiroshi (90343699)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results

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