OKA Naoki 岡直樹

Researcher Number	00299421
Affiliation (based on the past Project Information) *help	2006: 久留米大学, 医学部, 講師 2003: 久留米大学, 医学部, 講師 1998 – 2002: 久留米大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Circulatory organs internal medicine / Circulatory organs internal medicine Except Principal Investigator Circulatory organs internal medicine
Keywords	Principal Investigator LOXL / 遺伝子変異 / 心筋細胞 / フェニレフリン / 心筋肥大 / fibrosis / collagen / Lysyl oxydase / Cardiac Hypertrophy / トランスジェニックマウス … More / 心筋 / 活性酸素種 / 心肥大 / コラーゲン / 線維化 / Lysyl oxidase / maximum force / CaィイD12+ィエD1 sensitivity / muscle fiber / troponin T / mutation / cardiomyopathy / βミオシン重鎖 / 遺伝子導入 / 最大張力 / Ca^<2+>感受性 / スキンドファイバー / トロポニンT / 肥大型心筋症 / アポトーシス / 遺伝子異常 / 拡張型心筋症 / C / ラミンA / Gq / アデノウイルス / エンドセリン-1 / カベオリン-3 / ionomycin / 細胞内Ca^<2+> / α^1アドレナリン受容体 / カベオラ / カベオリン … More Except Principal Investigator cytokine / Adenylyl cyclase / β-adrenergic pathway / heart failure / IGF-1 / BNP / β-受容体リン酸化酵素 / アデニル酸シクラーゼ / β-受容体 / 交感神経 / 交感神経系 / サイトカイン / 心不全 / 荷電変化 / βミオシン重鎖 / トロポニンT / 遺伝子変異 / 肥大型心筋症 Less

Functional analysis of LOXL-1 in the myocardiumPrincipal Investigator
- Principal Investigator
  
  UEDA Tamenobu, 岡直樹
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kurume University
ラミンA/C遺伝子変異による拡張型心筋症発症機序の検討Principal Investigator
- Principal Investigator
  
  岡直樹
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kurume University
心筋カベオリン-3の機能解析(カベオリン-3特異的阻害物質の開発)Principal Investigator
- Principal Investigator
  
  岡直樹
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kurume University
肥大型心筋症の原因ならびに発症機序解明に関する分子遺伝学的研究
- Principal Investigator
  
  中田真詩
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kurume University
心血管系におけるカベオリンの発現制御および機能に関する検討Principal Investigator
- Principal Investigator
  
  岡直樹
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kurume University
Creation of a transgenic animal model of hypertrophic cardiomyopathy caused by cardiac troponin T mutation.Principal Investigator
- Principal Investigator
  
  OKA Naoki, 中田真詩
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kurume University
Relationship between β-adrenergic signaling pathway and cytokines in hypertensive heart failure.
- Principal Investigator
  
  IWAMI Gensho
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kurume University

All 2007 2006

All Journal Article Presentation Book

[Book] 肥大型心筋症ハンドブック、HCMの動物モデル2006
- Author(s)
  岡直樹, 大村治也, 今泉勉
- Total Pages
  317
- Publisher
  日本医事新報社(東京)
- Data Source
  KAKENHI-PROJECT-18590792
[Journal Article] Pulmonary Inflammation and Emphysema : Role of the Cytokines IL-18 and IL-132007
- Author(s)
  Hoshino T, Oka N, et al.
- Journal Title
  
  Am J Respir Crit Care Med. (Epub ahead of ptint)(In press)
- Data Source
  KAKENHI-PROJECT-18590792
[Journal Article] Pulmonary inflammation and enphysema. Role of cytokines IL-18 and IL-13.2007
- Author(s)
  Hoshino T, Kato S, Oka N, Imaoka H, Kinoshita T, Takei S, KitasatoY, Kawayama T, Imaizumi T, Yamada K, Young HA, Aizawa H
- Journal Title
  
  Am JRespir Grit Care Med 176
  
  Pages: 49-62
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590792
[Journal Article] 心筋症.内科外来診療実践ガイド-縮刷版- 和田攻,大久保昭行,矢崎義雄,大内尉義編,文光堂,東京2006
- Author(s)
  岡直樹, 大村治也, 今泉勉
- Journal Title
  
  内科外来診療実践ガイド 32
  
  Pages: 115-119
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590792
[Journal Article] Comparison of gene expression profiling in pressure and volume overload-induced myocardial hypertrophies in rats.2006
- Author(s)
  Miyazaki H, Oka N, et al.
- Journal Title
  
  Hypertens Res 29(12)
  
  Pages: 1029-1045
- NAID
  10018560950
- Data Source
  KAKENHI-PROJECT-18590792
[Journal Article] 肥大型心筋症の遺伝子異常と予後およびハイリスク症例の同定2006
- Author(s)
  岡直樹, 上田集宣, 今泉勉
- Journal Title
  
  Cardiac Practice 17(1)
  
  Pages: 35-39
- Data Source
  KAKENHI-PROJECT-18590792
[Journal Article] Comparison of gene expression profiling in pressure and volume overload-induced myocardial hypertrophies in rats.2006
- Author(s)
  Miyazaki H, Oka N, Koga A, Ohmura H, Ueda T, Imaizumi T
- Journal Title
  
  Hypertens Res 29(12)
  
  Pages: 1029-1045
- NAID
  10018560950
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590792
[Presentation] Roles of lysyl oxidase-like protein in heart.2007
- Author(s)
  Ohmura H, Oka N, Miyazaki H, Ueda T, Imaizumi T
- Organizer
  Japanese Circulation Society Meeting Scientific Session
- Place of Presentation
  Kobe
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590792
[Presentation] Behavior and role of lysyl oxidase-like protein in development of cardiac hypertrophy.2006
- Author(s)
  Ohmura H, Oka N, Miyazaki H, Ueda T, Imaizumi T
- Organizer
  The 2nd China-Japan Cardiovascular Forum
- Place of Presentation
  Beijin, China
- Year and Date
  2006-11-04
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590792
[Presentation] Role of Caveolin-3 in cardiac hypertrophy.2006
- Author(s)
  Oka N, Kikuchi T, Koga A, Ohmura H, Miyazaki H, Imaizumi T
- Organizer
  The International symposium of Cardiology Frontiers Cardiomyopathy and Heart Failure
- Place of Presentation
  Sapporo, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590792
[Presentation] Role of Caveolin-3 in cardiac hypertrophy2006
- Author(s)
  Oka N, et. al.
- Organizer
  The International symposium of Cardiology Frontiers:Cardiomyopathy and Heart Failure
- Place of Presentation
  札幌
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590792

1. IWAMI Gensho (90203405)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. 中田真詩 (70180304)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. KIKUCHI Toshio (20289432)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. UEDA Tamenobu (50389251)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
5. 西宏文 (60189248)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. NAKAURA Hiroyuki (50279171)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KOGA Akimasa (10309776)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. MIYAZAKI Hiroshi (90343699)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results

OKA Naoki 岡 直樹

Research Projects

Research Products

Co-Researchers

Functional analysis of LOXL-1 in the myocardiumPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ラミンA/C遺伝子変異による拡張型心筋症発症機序の検討Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

心筋カベオリン-3の機能解析(カベオリン-3特異的阻害物質の開発)Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

肥大型心筋症の原因ならびに発症機序解明に関する分子遺伝学的研究

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

心血管系におけるカベオリンの発現制御および機能に関する検討Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Creation of a transgenic animal model of hypertrophic cardiomyopathy caused by cardiac troponin T mutation.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Relationship between β-adrenergic signaling pathway and cytokines in hypertensive heart failure.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 肥大型心筋症ハンドブック、HCMの動物モデル2006

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Pulmonary Inflammation and Emphysema : Role of the Cytokines IL-18 and IL-132007

Author(s)

Journal Title

Data Source

[Journal Article] Pulmonary inflammation and enphysema. Role of cytokines IL-18 and IL-13.2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] 心筋症.内科外来診療実践ガイド-縮刷版- 和田攻,大久保昭行,矢崎義雄,大内尉義編,文光堂,東京2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Comparison of gene expression profiling in pressure and volume overload-induced myocardial hypertrophies in rats.2006

Author(s)

Journal Title

NAID

Data Source

[Journal Article] 肥大型心筋症の遺伝子異常と予後およびハイリスク症例の同定2006

Author(s)

Journal Title

Data Source

[Journal Article] Comparison of gene expression profiling in pressure and volume overload-induced myocardial hypertrophies in rats.2006

Author(s)

Journal Title

NAID

Description

Data Source

OKA Naoki 岡直樹