Sugase Kenji 菅瀬謙治

… Alternative Names

SUGASE Kenji 菅瀬謙治

菅瀬謙治スガセケンジ

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Researcher Number	00300822
Other IDs	https://orcid.org/0000-0001-8623-7743
Affiliation (Current)	2024: 京都大学, 農学研究科, 教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 京都大学, 農学研究科, 教授 2016 – 2021: 京都大学, 工学研究科, 准教授 2015: 京都大学, 工学(系)研究科(研究院), 准教授 2013 – 2014: 公益財団法人サントリー生命科学財団, その他部局等, 主席研究員 2013: 公益財団法人サントリー生命科学財団生物有機科学研究所, 主席研究員 … More 2013: 公益財団法人サントリー生命科学財団, その他部局等, 研究員 2013: 公財)サントリー生命科学財団 2010 – 2012: 公益財団法人サントリー生命科学財団, 生物有機科学研究所, 主席研究員 2011: (財)サントリー生物有機科学研究所, 主席研究員 2011: 公益法人サントリー生命科学財団, 生物有機科学研究所, 主席研究員 2009: Suntory Institute for Bioorganic Research, 主席研究員 2009: サントリー生物有機科学研究所, 主任研究員 2004: サントリー生物研, 研究員 2003: 財団法人サントリー生物有機科学研究所, 研究員 Less
Review Section/Research Field	Principal Investigator Transformative Research Areas, Section (III) / Medium-sized Section 43:Biology at molecular to cellular levels, and related fields / Structural biochemistry / Basic Section 43040:Biophysics-related / Complex systems / Medium-sized Section 13:Condensed matter physics and related fields / Biomolecular chemistry and related fields / Biophysics / Science and Engineering / Living organism molecular science … More Except Principal Investigator … More Structural biochemistry / Basic Section 32010:Fundamental physical chemistry-related / Transformative Research Areas, Section (III) / Living organism molecular science / Biological Sciences Less
Keywords	Principal Investigator NMR / Rheo-NMR / タンパク質 / アミロイド線維 / in-cell NMR / 蛋白質 / αシヌクレイン / 剪断流 / ATP / アミロイド線維化 … More / 生物物理 / 動的構造 / 凝集 / 電気泳動 / 電場 / 膜なしオルガネラ / 電場NMR / 非膜オルガネラ / 液-液相分離 / 溶液環境 / エピゲノム修飾 / 二本鎖DNA / Rheo-MD / 会合 / 細胞内環境 / タンパク質‐薬剤相互作用 / 化学交換 / 19F-NMR / 解離定数 / 難水溶性薬剤 / タンパク質－薬剤相互作用 / 細胞抽出液 / 安定性 / 剪断力 / 夾雑環境 / 安定化/不安定化 / 細胞内夾雑環境 / 線維化 / タンパク質凝集 / 乱流 / off-center Couette cell / 速度イメージング / 流体 / レオロジー / 高分子構造・物性 / リン酸化ユビキチン / PINK1 / ユビキチン / Parkin / 分子認識 / 大量発現系 / リフォールディング / parkin / 高速NMR法 / 高速測定 / 揺らぎ / 分子認識および相互作用 / 分子認識及び相互作用 / 揺らぎの検出 / マイクロカロリメトリー / リン脂質膜 / グレリン … More Except Principal Investigator NMR / モンテカルロ法 / 分子シミュレーション / 超分子ゲル / 酸化還元 / 3D-RISM / アミロイド線維化 / 液-液相分離 / 動的溶液環境 / アミロイド線維 / 天然変性タンパク質 / 非膜型オルガネラ / 液液相分離 / 蛋白質構造 / 立体構造解析 / NDSB / 構造多型 / 効率化 / 収率 / 精製 / 抗体 / 変性 / 凝集 / 溶解度 / 分子サイズ / オスモライト / 運動性 / メカニズム / スルホベタイン / 安定化 / 凝集防止 / タンパク質 / 標識体 / 鉄輸送 / 光親和標識体 / オオムギ / イネ科食物 / 基質選択性 / ムギネ酸鉄錯体トランスポーター / ファイトシデロフォア / トランスポーター / イネ科植物 / 鉄錯体 / ムギネ酸 / 生子 / 蛋白 / ＮＭＲ / 天然変性 / 質量分析 / 生体分子 / 蛋白質 Less

Investigation of molecular aggregation control mechanism by solution environment and creation of molecular design tools
- Principal Investigator
  
  吉田紀生
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 32010:Fundamental physical chemistry-related
- Research Institution
  Nagoya University
Elucidation of the mechanism of protein aggregation in flow by using Rheo-NMR and Rheo-MDPrincipal Investigator
- Principal Investigator
  
  菅瀬謙治
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Kyoto University
動的溶液科学の推進
- Principal Investigator
  
  関山直孝
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Kyoto University
Atomic-level analysis of proteins responding to dynamic solution environments using NMRPrincipal Investigator
- Principal Investigator
  
  菅瀬謙治
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Kyoto University
Development of analytical platform for proteins in electric field and its applicationPrincipal Investigator
- Principal Investigator
  
  菅瀬謙治
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  Kyoto University
NMR study on local structural fluctuations of double-stranded DNAPrincipal Investigator
- Principal Investigator
  
  菅瀬謙治
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Kyoto University
Elucidation of the mechanism of amyloid fibrillation of alpha-synuclein starting from liquid-liquid phase separationPrincipal Investigator
- Principal Investigator
  
  菅瀬謙治
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43040:Biophysics-related
- Research Institution
  Kyoto University
Development of a new methodology for determining dissociation constants of proteins and drugs in cellsPrincipal Investigator
- Principal Investigator
  
  Sugase Kenji
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  Kyoto University
Velocity imaging of turbulence flow using Rheo-NMRPrincipal Investigator
- Principal Investigator
  
  Sugase Kenji
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 13:Condensed matter physics and related fields
- Research Institution
  Kyoto University
Analysis of the effects of crowded environment and shear force to proteins using Rheo-NMRPrincipal Investigator
- Principal Investigator
  
  菅瀬謙治
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  Kyoto University
Elucidation of the mechanism of amyloid fibrillation using Rheo-NMR and development of a new Rheo-NMR instrumentPrincipal Investigator
- Principal Investigator
  
  Sugase Kenji
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Biomolecular chemistry and related fields
- Research Institution
  Kyoto University
Activation mechanism of ubiquitin ligase parkin by PINK1 and phosphorylated ubiquitinPrincipal Investigator
- Principal Investigator
  
  Sugase Kenji
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kyoto University
Ultra-fast NMR measurement to analyze dynamics of Sox2 in cellsPrincipal Investigator
- Principal Investigator
  
  SUGASE Kenji
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biophysics
- Research Institution
  Suntory Foundation for Life Sciences
Elucidating a DNA recognition mechanism of a transcriptional factor protein by characterizing dynamic processes of specific/non-specific DNA-bound complexes
- Principal Investigator
  
  HARADA ERISA
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Suntory Foundation for Life Sciences
NMR緩和分散法によるiPS細胞誘導因子Oct3/4の揺らぎの検出Principal Investigator
- Principal Investigator
  
  菅瀬謙治
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Suntory Institute for Bioorganic Research
Characterization of structural dynamics of intrinsically disordered proteins
- Principal Investigator
  
  AKASHI Satoko
- Project Period (FY)
  2009 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Yokohama City University
Iron acquisition mechanism of graminaceous plants by mugineic acids
- Principal Investigator
  
  MURATA Yoshiko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  Suntory Institute for Bioorganic Research
Mechanism analysis of sulfobetaines' activity to prevent protein aggregation and application of sulfobetaines to unstable proteins
- Principal Investigator
  
  WAKAMATSU Kaori
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Gunma University
Elucidation of dynamics and function of an iPS cell reprogramming factor Sox2 from the view point of an intrinsically disordered proteinPrincipal Investigator
- Principal Investigator
  
  SUGASE Kenji
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  公益財団法人サントリー生命科学財団
   Suntory Institute for Bioorganic Research
膜との相互作用によるグレリンの生理活性の調節機構Principal Investigator
- Principal Investigator
  
  菅瀬謙治
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  Suntory Institute for Bioorganic Research

[Book] ＮＭＲによる有機材料分析とその試料前処理、データ解釈2021
- Author(s)
  森本大智、菅瀬謙治
- Total Pages
  676
- Publisher
  技術情報協会
- ISBN
  9784861048609
- Data Source
  KAKENHI-PROJECT-18KK0075
[Book] Experimental Approaches of NMR Spectroscopy2018
- Author(s)
  Walinda E, Sugase K
- Total Pages
  636
- Publisher
  Springer
- ISBN
  9789811059650
- Data Source
  KAKENHI-PROJECT-15H04342
[Book] Water and Biomolecules : Physical Chemistry of Life Phenomena (Biological and Medical Physics, Biomedical Engineering)2009
- Author(s)
  Wright, P.E., Felitsky, D.J., Sugase, K., Dyson, H.J.
- Total Pages
  307
- Publisher
  Springer-Verlag
- Data Source
  KAKENHI-PLANNED-21113003
[Book] Water and Biomolecules : Physical Chemistry of Life Phenomena(Biological and Medical Physics, Biomedical Engineering)(ed.Kuwajima K, Goto Y, Hirata F, Terazima M, Kataoka M)2009
- Author(s)
  Wright PE, Felitsky DJ, Sugase K, Dyson HJ
- Total Pages
  307
- Publisher
  Springer-Verlag
- Data Source
  KAKENHI-PUBLICLY-21107531
[Book] Water and Biomolecules : Physical Chemistry of Life Phenomena (Biological and Medical Physics, Biomedical Engineering) (ed. Kuwajima K, Goto Y, Hirata F, Terazima M, Kataoka M)2009
- Author(s)
  Wright PE, Felitsky DJ, Sugase K, Dyson HJ
- Total Pages
  307
- Data Source
  KAKENHI-PROJECT-21770126
[Book] Water and Biomolecules : Physical Chemistry of Life Phenomena(Biological and Medical Physics, Biomedical Engineering)(ed.Kuwajima K, Goto Y, Hirata F, Terazima M, Kataoka M)2009
- Author(s)
  Wright PE, Felitsky DJ, Sugase K, Dyson HJ
- Total Pages
  307
- Publisher
  Springer-Verlag
- Data Source
  KAKENHI-PROJECT-21770126
[Journal Article] Rheo‐NMR Spectroscopy for Cryogenic‐Probe‐Equipped NMR Instruments to Monitor Protein Aggregation2022
- Author(s)
  Morimoto Daichi、Walinda Erik、Yamamoto Akihiko、Scheler Ulrich、Sugase Kenji
- Journal Title
  
  Current Protocols
  
  Volume: 2 Issue: 12
- DOI
  10.1002/cpz1.617
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06161, KAKENHI-PLANNED-22H05088, KAKENHI-PROJECT-21H02442, KAKENHI-PROJECT-20K15756
[Journal Article] Transient Diffusive Interactions with a Protein Crowder Affect Aggregation Processes of Superoxide Dismutase 1 β-Barrel2021
- Author(s)
  Iwakawa Naoto、Morimoto Daichi、Walinda Erik、Leeb Sarah、Shirakawa Masahiro、Danielsson Jens、Sugase Kenji
- Journal Title
  
  The Journal of Physical Chemistry B
  
  Volume: 125 Issue: 10 Pages: 2521-2532
- DOI
  10.1021/acs.jpcb.0c11162
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K15757, KAKENHI-PROJECT-18KK0075, KAKENHI-PROJECT-18J22192, KAKENHI-PROJECT-18K19297, KAKENHI-PROJECT-18K14665
[Journal Article] Expression, solubility monitoring, and purification of the co-folded LUBAC LTM domain by structure-guided tandem folding in autoinducing cultures2021
- Author(s)
  Walinda Erik、Morimoto Daichi、Sorada Tomoki、Iwai Kazuhiro、Sugase Kenji
- Journal Title
  
  Protein Expression and Purification
  
  Volume: 187 Pages: 105953-105953
- DOI
  10.1016/j.pep.2021.105953
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18KK0075, KAKENHI-PLANNED-18H05499, KAKENHI-PROJECT-17H06174, KAKENHI-PROJECT-20K15757, KAKENHI-PROJECT-20K15756
[Journal Article] Multiple-State Monitoring of SOD1 Amyloid Formation at Single-Residue Resolution by Rheo-NMR Spectroscopy2021
- Author(s)
  Iwakawa Naoto、Morimoto Daichi、Walinda Erik、Shirakawa Masahiro、Sugase Kenji
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 143 Issue: 28 Pages: 10604-10613
- DOI
  10.1021/jacs.1c02974
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18KK0075, KAKENHI-PROJECT-20H00453, KAKENHI-PROJECT-20K15757, KAKENHI-PROJECT-20K15756
[Journal Article] Effects of Weak Nonspecific Interactions with ATP on Proteins2021
- Author(s)
  Nishizawa Mayu、Walinda Erik、Morimoto Daichi、Kohn Benjamin、Scheler Ulrich、Shirakawa Masahiro、Sugase Kenji
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 143 Issue: 31 Pages: 11982-11993
- DOI
  10.1021/jacs.0c13118
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0075, KAKENHI-PROJECT-20H00453, KAKENHI-PROJECT-20K15757, KAKENHI-PROJECT-20K15756
[Journal Article] Rigorous analysis of the interaction between proteins and low water-solubility drugs by qNMR-aided NMR titration experiments2021
- Author(s)
  Hirakawa Takuya、Walinda Erik、Morimoto Daichi、Sugase Kenji
- Journal Title
  
  Physical Chemistry Chemical Physics
  
  Volume: 23 Issue: 38 Pages: 21484-21488
- DOI
  10.1039/d1cp03175a
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21391, KAKENHI-PROJECT-20K15757, KAKENHI-PROJECT-20K15756
[Journal Article] Molecular recognition and deubiquitination of cyclic K48-linked ubiquitin chains by OTUB12021
- Author(s)
  Sorada Tomoki、Morimoto Daichi、Walinda Erik、Sugase Kenji
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 562 Pages: 94-99
- DOI
  10.1016/j.bbrc.2021.05.031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18KK0075
[Journal Article] Backbone resonance assignments of the A2 domain of mouse von Willebrand factor2021
- Author(s)
  Morimoto Daichi、Osugi Masanori、Mahana Yutaka、Walinda Erik、Shirakawa Masahiro、Sugase Kenji
- Journal Title
  
  Biomolecular NMR Assignments
  
  Volume: 15 Issue: 2 Pages: 427-431
- DOI
  10.1007/s12104-021-10041-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18KK0075, KAKENHI-PROJECT-20H00453, KAKENHI-PROJECT-20K15757, KAKENHI-PROJECT-20K15756
[Journal Article] Pinpoint analysis of a protein in slow exchange using F1F2-selective ZZ-exchange spectroscopy: assignment and kinetic analysis.2020
- Author(s)
  Mayu Nishizawa, Erik Walinda, Daichi Morimoto, Kenji Sugase
- Journal Title
  
  Journal of Biomolecular NMR
  
  Volume: 0 Issue: 4-5 Pages: 0-0
- DOI
  10.1007/s10858-020-00309-x
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14665, KAKENHI-PUBLICLY-18H04551, KAKENHI-PROJECT-19J13259
[Journal Article] Visualizing protein motion in Couette flow by all-atom molecular dynamics2020
- Author(s)
  Walinda Erik、Morimoto Daichi、Shirakawa Masahiro、Scheler Ulrich、Sugase Kenji
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - General Subjects
  
  Volume: 1864 Issue: 2 Pages: 129383-129383
- DOI
  10.1016/j.bbagen.2019.06.006
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19297, KAKENHI-PROJECT-18KK0075, KAKENHI-PUBLICLY-18H04551, KAKENHI-WRAPUP-19H05452, KAKENHI-PROJECT-17K19196, KAKENHI-PROJECT-16K18503, KAKENHI-PROJECT-18K14665
[Journal Article] 高感度Rheo-NMRによるアミロイド線維化過程のその場観察2019
- Author(s)
  森本大智、菅瀬謙治
- Journal Title
  
  月刊「細胞」
  
  Volume: 685 Pages: 32-36
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18KK0075
[Journal Article] 生体分子レオロジーNMRの開発と応用2019
- Author(s)
  森本大智、菅瀬謙治
- Journal Title
  
  日本核磁気共鳴学会機関誌
  
  Volume: 10 Pages: 64-48
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18KK0075
[Journal Article] 高感度Rheo-NMRによるアミロイド線維化過程のその場観察2019
- Author(s)
  森本大智、菅瀬謙治
- Journal Title
  
  月刊「細胞」
  
  Volume: 51 Pages: 32-36
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19196
[Journal Article] 高感度Rheo-NMRによるアミロイド線維化過程のその場観察2019
- Author(s)
  森本大智、菅瀬謙治
- Journal Title
  
  月刊「細胞」
  
  Volume: 51 Pages: 32-36
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-18H04551
[Journal Article] 生体分子レオロジーNMRの開発と応用2019
- Author(s)
  森本大智、菅瀬謙治
- Journal Title
  
  日本核磁気共鳴学会機関誌
  
  Volume: 10 Pages: 64-68
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-18H04551
[Journal Article] 生体分子レオロジーNMRの開発と応用2019
- Author(s)
  森本大智、菅瀬謙治
- Journal Title
  
  日本核磁気共鳴学会機関誌
  
  Volume: 10 Pages: 64-68
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19196
[Journal Article] Overview of Relaxation Dispersion NMR Spectroscopy to Study Protein Dynamics and Protein-Ligand Interactions2018
- Author(s)
  Walinda Erik、Morimoto Daichi、Sugase Kenji
- Journal Title
  
  Current Protocols in Protein Science
  
  Volume: 92 Issue: 1
- DOI
  10.1002/cpps.57
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K18503, KAKENHI-PROJECT-15H04342, KAKENHI-PUBLICLY-18H04551
[Journal Article] Resolving biomolecular motion and interactions by R2 and R1ρ relaxation dispersion NMR2018
- Author(s)
  Walinda Erik、Morimoto Daichi、Sugase Kenji
- Journal Title
  
  Methods
  
  Volume: 148 Pages: 28-38
- DOI
  10.1016/j.ymeth.2018.04.026
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18503, KAKENHI-PROJECT-18K14665, KAKENHI-PUBLICLY-18H04551, KAKENHI-PROJECT-15H04342
[Journal Article] High-sensitivity Rheo-NMR spectroscopy for protein studies.2017
- Author(s)
  Morimoto D., Walinda E., Iwakawa N., Nishizawa M., Kawata Y., Yamamoto A., Shirakawa M., Scheler U., Sugase K.
- Journal Title
  
  Anal. Chem.
  
  Volume: 89 Issue: 14 Pages: 7286-7290
- DOI
  10.1021/acs.analchem.7b01816
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19196, KAKENHI-PROJECT-16K18503
[Journal Article] F1F2-selective NMR spectroscopy2017
- Author(s)
  Walinda Erik、Morimoto Daichi、Shirakawa Masahiro、Sugase Kenji
- Journal Title
  
  Journal of Biomolecular NMR
  
  Volume: 68 Issue: 1 Pages: 41-52
- DOI
  10.1007/s10858-017-0113-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K18503, KAKENHI-PLANNED-26119004, KAKENHI-PROJECT-15H04342
[Journal Article] Real-time observation of the interaction between thioflavin T and an amyloid protein by using high-sensitivity Rheo-NMR.2017
- Author(s)
  Iwakawa N., Morimoto D., Walinda E., Kawata Y., Shirakawa M., Sugase K.
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 18 Issue: 11 Pages: 2271-2271
- DOI
  10.3390/ijms18112271
- NAID
  120006501319
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19196, KAKENHI-PROJECT-16K18503, KAKENHI-PLANNED-26119004
[Journal Article] Practical considerations for investigation of protein conformational dynamics by 15N R 1ρ relaxation dispersion.2017
- Author(s)
  Walinda E, Morimoto D, Shirakawa M, Sugase K.
- Journal Title
  
  Biomol NMR.
  
  Volume: 印刷中 Issue: 3 Pages: 201-209
- DOI
  10.1007/s10858-017-0097-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-26119004, KAKENHI-PROJECT-15H04342, KAKENHI-PROJECT-16K18503
[Journal Article] Efficient identification and analysis of chemical exchange in biomolecules by R1rho relaxation dispersion with Amaterasu2016
- Author(s)
  Walinda, E. Morimoto, D. Nishizawa, M. Shirakawa, M. Sugase, K.
- Journal Title
  
  Bioinformatics
  
  Volume: 32 Issue: 16 Pages: 2539-2541
- DOI
  10.1093/bioinformatics/btw188
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04342, KAKENHI-PROJECT-16K18503
[Journal Article] Dual Function of Phosphoubiquitin in E3 Activation of Parkin2016
- Author(s)
  Walinda, E. Morimoto, D. Sugase, K. Shirakawa, M.
- Journal Title
  
  J Biol Chem
  
  Volume: 291 Issue: 32 Pages: 16879-16891
- DOI
  10.1074/jbc.m116.728600
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04342, KAKENHI-PROJECT-16K18503
[Journal Article] Quantitative analysis of protein–ligand interactions by NMR.2016
- Author(s)
  4.A. Furukawa, T. Konuma, S. Yanaka, K. Sugase
- Journal Title
  
  Prog. Nucl. Magn. Reson. Sp.
  
  Volume: 96 Pages: 47-57
- DOI
  10.1016/j.pnmrs.2016.02.002
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04342
[Journal Article] Quantitative analysis of location- and sequence-dependent deamination by APOBEC3G using real-time NMR spectroscopy2014
- Author(s)
  Furukawa, A., Sugase, K., Morishita, R., Nagata, T., Kodaki, T., Takaori-Kondo, A., Ryo, A., Katahira, M.
- Journal Title
  
  Angew. Chem. Int. Ed. Engl.
  
  Volume: 53 Issue: 9 Pages: 2349-2352
- DOI
  10.1002/anie.201309940
- NAID
  120005647511
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-21113003, KAKENHI-PROJECT-23390110, KAKENHI-PROJECT-23570146, KAKENHI-PUBLICLY-24113710, KAKENHI-PUBLICLY-24121714, KAKENHI-PROJECT-24390115, KAKENHI-PUBLICLY-25115507, KAKENHI-PROJECT-25650056, KAKENHI-PUBLICLY-26104520, KAKENHI-PROJECT-26840040
[Journal Article] Solution Structure of the Ubiquitin-associated (UBA) Domain of Human Autophagy Receptor NBR1 and its Interaction with Ubiquitin and Polyubiquitin.2014
- Author(s)
  E. Walinda, D. Morimoto. K. Sugase. T. Konuma. H. Tochio, M. Shirakawa
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: (印刷中) Issue: 20 Pages: 13890-13902
- DOI
  10.1074/jbc.m114.555441
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-11J06373, KAKENHI-PLANNED-21113003, KAKENHI-PUBLICLY-25112514, KAKENHI-PLANNED-26119004
[Journal Article] Solid-state NMR spectra of lipid- anchored proteins under magic angle spinning2014
- Author(s)
  Nomura, K., Harada, E., Sugase, K., Shimamoto, K.
- Journal Title
  
  J. Phys. Chem. B.
  
  Volume: 118 Pages: 2405-2413
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24770106
[Journal Article] Solid-state NMR spectra of lipid-anchored proteins under magic angle spinning.2014
- Author(s)
  Nomura, K., Harada, E., Sugase, K., Shimamoto, K.
- Journal Title
  
  J. Phys. Chem. B.
  
  Volume: 118 Issue: 9 Pages: 2405-2413
- DOI
  10.1021/jp4124106
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21113003, KAKENHI-PROJECT-25410187, KAKENHI-PROJECT-25650056
[Journal Article] Solution structure of the Q41N variant of ubiquitin as a model for the alternatively folded N2 state of ubiquitin2013
- Author(s)
  Soichiro Kitazawa, Tomoshi Kameda, Maho Yagi-Utsumi, Kenji Sugase, Nicola J. Baxter, Koichi Kato, Michael P. Williamson, Ryo Kitahara.
- Journal Title
  
  Biochemistry
  
  Volume: 52 Issue: 11 Pages: 1874-1885
- DOI
  10.1021/bi301420m
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23870043, KAKENHI-PROJECT-25650056, KAKENHI-PLANNED-20107004, KAKENHI-PLANNED-21113003, KAKENHI-PUBLICLY-23107729
[Journal Article] Fast and accurate fitting of relaxation dispersion data using the flexible software package GLOVE2013
- Author(s)
  Sugase, K., Konuma, T., Lansing, J.C., Wright, P.E.
- Journal Title
  
  J. Biomol. NMR
  
  Volume: 56 Issue: 3 Pages: 275-283
- DOI
  10.1007/s10858-013-9747-5
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21113003, KAKENHI-PROJECT-25650056, KAKENHI-PROJECT-25840059
[Journal Article] The monomer-seed interaction mechanism in the formation of the β2-microglobulin amyloid fibril clarified by solution NMR techniques.2012
- Author(s)
  Yanagi K
- Journal Title
  
  J. Mol. Biol.
  
  Volume: 422 Issue: 3 Pages: 390-402
- DOI
  10.1016/j.jmb.2012.05.034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390075, KAKENHI-PROJECT-24370067, KAKENHI-PLANNED-21113003, KAKENHI-PUBLICLY-23107719
[Journal Article] 実践relaxation dispersion法2012
- Author(s)
  菅瀬謙治
- Journal Title
  
  NMR
  
  Volume: 3 Pages: 82-85
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21113003
[Journal Article] Elucidating slow binding kinetics of a protein without observable bound resonances by longitudinal relaxation NMR spectroscopy2011
- Author(s)
  Sugase, K.
- Journal Title
  
  J. Biomol. NMR
  
  Volume: 50 Issue: 3 Pages: 219-227
- DOI
  10.1007/s10858-011-9511-7
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21113003
[Journal Article] Boosting protein dynamics studies using quantitative nonuniform sampling NMR spectroscopy2011
- Author(s)
  Matsuki Y, Konuma T, Fujiwara T, Sugase K
- Journal Title
  
  J.Phys.Chem.B
  
  Volume: 115 Issue: 46 Pages: 13740-13745
- DOI
  10.1021/jp2081116
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21113003
[Journal Article] Calcitonin in a protochordate, Ciona intestinalis―the prototype of the vertebrate calcitonin/calcitonin gene-related peptide superfamily2009
- Author(s)
  Sekiguchi T, Suzuki N, Fujiwara N, Aoyama M, Kawada T, Sugase K, Murata Y, Sasayama Y, Ogasawara M, Satake H
- Journal Title
  
  FEBS J. 276
  
  Pages: 4437-4447
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21107531
[Journal Article] Calcitonin in a protochordate, Ciona intestinalis-the prototype of the vertebrate calcitonin/calcitonin gene-related peptide superfamily2009
- Author(s)
  Sekiguchi T, Suzuki N, Fujiwara N, Aoyama M, Kawada T, Sugase K, Murata Y, Sasayama Y, Ogasawara M, Satake H
- Journal Title
  
  FEBS J. 276
  
  Pages: 4437-4447
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21770126
[Journal Article] Calcitonin in a protochordate, Ciona intestinalis--the prototype of the vertebrate calcitonin/calcitonin gene-related peptide superfamily.2009
- Author(s)
  Sekiguchi T, Suzuki N, Fujiwara N, Aoyama M, Kawada T, Sugase K, Murata Y, Sasayama Y, Ogasawara M, Satake H
- Journal Title
  
  FEBS J. 276
  
  Pages: 4437-4447
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21113003
[Journal Article] Calcitonin in a protochordate, Ciona intestinalis--the prototype of the vertebrate calcitonin/calcitonin gene-related peptide superfamily.2009
- Author(s)
  Sekiguchi T, Suzuki N, Fujiwara N, Aoyama M, Kawada T, Sugase K, Murata Y, Sasayama Y, Ogasawara M, Satake H
- Journal Title
  
  FEBS J. Vol.276
  
  Pages: 4437-4447
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21770126
[Journal Article] Elucidating slow binding kinetics of a protein without observable bound resonances by longitudinal relaxation NMR spectroscopy
- Author(s)
  Kenji Sugase
- Journal Title
  
  Journal of Biomolecular NMR
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21770126
[Journal Article] Elucidating slow binding kinetics of a protein without observable bound resonances by longitudinal relaxation NMR spectroscopy
- Author(s)
  Sugase K
- Journal Title
  
  J.Biomol.NMR in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21770126
[Journal Article] Elucidating slow binding kinetics of a protein without observable bound resonances by longitudinal relaxation NMR spectroscopy
- Author(s)
  Kenji Sugase
- Journal Title
  
  Journal of Biomolecular NMR
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21107531
[Journal Article] Lipopolysaccharide induces raft domain expansion in membrane composed of a phospholipid-cholesterol-sphingomyelin ternary system.
- Author(s)
  Nomura K, Maeda M, Sugase K, Kusumoto S
- Journal Title
  
  Innate Immun. in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21770126
[Patent] 剪断流を発生させる器具2019
- Inventor(s)
  菅瀬謙治、森本大智、保科好秀
- Industrial Property Rights Holder
  菅瀬謙治、森本大智、保科好秀
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-111013
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-17K19196
[Patent] 剪断流を発生させる器具2019
- Inventor(s)
  菅瀬謙治、森本大智、保科好秀
- Industrial Property Rights Holder
  菅瀬謙治、森本大智、保科好秀
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-111013
- Filing Date
  2019
- Data Source
  KAKENHI-PUBLICLY-18H04551
[Presentation] 分子夾雑環境による免疫抑制剤結合タンパク質FKBP12の薬剤認識への影響のNMR動的構造解析2021
- Author(s)
  平河卓也、森本大智、菅瀬謙治、白川昌宏
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-20K21391
[Presentation] Highly Accurate Analysis of the Interaction Between Proteins and Low Water-solubility Drugs by qNMR-aided NMR Titration Experiments2021
- Author(s)
  Takuya Hirakawa, Daichi Morimoto, Kenji Sugase
- Organizer
  ISMAR-APNMR2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21391
[Presentation] Elucidation of Fibrillation Mechanism of ALS-Related Protein SOD12019
- Author(s)
  Kenji Sugase
- Organizer
  IPR Seminar
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04551
[Presentation] In situ Monitoring of Amyloid Fibril Formation Processes Using Rheo-NMR2019
- Author(s)
  Kenji Sugase, Daichi Morimoto, Walinda Erik, Naoto Iwakawa, Akihiko Yamamoto, Ulrich Scheler
- Organizer
  8th APNMR
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19196
[Presentation] In situ Monitoring of Amyloid Fibril Formation Processes Using Rheo-NMR2019
- Author(s)
  Kenji Sugase
- Organizer
  8th APNMR
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0075
[Presentation] In situ Monitoring of Amyloid Fibril Formation Processes Using Rheo-NMR2019
- Author(s)
  Kenji Sugase, Daichi Morimoto, Walinda Erik, Naoto Iwakawa, Akihiko Yamamoto, Ulrich Scheler
- Organizer
  8th APNMR
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04551
[Presentation] High-Sensitivity Rheo-NMR Spectroscopy for Protein Studies2018
- Author(s)
  Kenji Sugase
- Organizer
  EUROMAR 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19196
[Presentation] 高感度Rheo-NMRによるタンパク質線維化のその場解析2018
- Author(s)
  菅瀬謙治
- Organizer
  日本表面真空学会 2018年9月研究例会
- Invited
- Data Source
  KAKENHI-PROJECT-17K19196
[Presentation] High-sensitivity Rheo-NMR spectroscopy for protein studies.2017
- Author(s)
  Sugase K
- Organizer
  JGP-Chem Kyoto-Bordeaux Faculty & Student Research Workshop on Chiral Nanostructures for Photonic Applications
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19196
[Presentation] High-sensitivity Rheo-NMR spectroscopy for protein studies.2017
- Author(s)
  Sugase K
- Organizer
  ISMAR 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19196
[Presentation] Characterizing Conformational Flexibility of a DNA Binding Protein2014
- Author(s)
  Erisa Harada, Tsuyoshi Konuma, Kenji Sugase
- Organizer
  55th Experimental Nuclear Magnetic Resonance Conference
- Place of Presentation
  アメリカ　ボストン
- Data Source
  KAKENHI-PROJECT-24770106
[Presentation] HLA-HIV由来抗原ペプチド複合体-水のダイナミクスと抗原提示能2014
- Author(s)
  菅瀬謙治
- Organizer
  関西創薬化学コミュニティ
- Place of Presentation
  新大阪
- Invited
- Data Source
  KAKENHI-PROJECT-25650056
[Presentation] Characterizing Conformational Flexibility of a DNA Binding Protein2014
- Author(s)
  Erisa Harada, Tsuyoshi Konuma, Kenji Sugase
- Organizer
  55th Experimental Nuclear Magnetic Resonance Conference
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-24770106
[Presentation] Relaxation dispersion spectroscopy2013
- Author(s)
  Sugase, K.
- Organizer
  2013 Taiwan magnetic resonance society annual meeting
- Place of Presentation
  Chiayi, Taiwan
- Year and Date
  2013-01-29
- Invited
- Data Source
  KAKENHI-PLANNED-21113003
[Presentation] Extracting Information on Protein Dynamics from Crowded NMR Spectra Using Relaxation Dispersion Difference2013
- Author(s)
  Tsuyoshi Konuma, Erisa Harada, Kenji Sugase
- Organizer
  5th Asia-Pacific NMR Symposium
- Place of Presentation
  the Brisbane Convention and Exhibition Centre, Brisbane, Australia
- Data Source
  KAKENHI-PLANNED-21113003
[Presentation] Mechanism of coupled folding and binding of an intrinsically disordered protein2013
- Author(s)
  Kenji Sugase
- Organizer
  2013 Taiwan magnetic resonance society annual meeting
- Place of Presentation
  Chiayi, Taiwan
- Year and Date
  2013-01-29
- Invited
- Data Source
  KAKENHI-PLANNED-21113003
[Presentation] Analysis of protein dynamics in living human cells2013
- Author(s)
  Kenji Sugase, Erisa Harada, Toshio Takahashi, Shoko Mori
- Organizer
  第３６回分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24770106
[Presentation] Mechanism of the distal regulation of substrate binding through intrinsic fluctuation in an enzyme2013
- Author(s)
  Kenji Sugase
- Organizer
  The 10th Korea-Japan Bilateral Symposium on Biological NMR
- Place of Presentation
  ソウル、韓国
- Invited
- Data Source
  KAKENHI-PROJECT-25650056
[Presentation] Analysis of protein dynamics in living human cells2013
- Author(s)
  Kenji Sugase
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25650056
[Presentation] 揺らぎが制御するヘム分解酵素反応の遠位効果2013
- Author(s)
  菅瀬謙治
- Organizer
  第14回若手NMR研究会
- Place of Presentation
  京都トラベラーズ・イン、京都
- Invited
- Data Source
  KAKENHI-PLANNED-21113003
[Presentation] Mechanism of the distal regulation of substrate binding through intrinsic fluctuation in an enzyme2013
- Author(s)
  Kenji Sugase
- Organizer
  The 10^<th> Korea-Japan Bilaterial Symposium on Biological NMR
- Place of Presentation
  Seuol, Korea
- Year and Date
  2013-07-04
- Data Source
  KAKENHI-PROJECT-24770106
[Presentation] Extracting information on protein dynamics from crowded NMR spectra using relaxation dispersion difference2013
- Author(s)
  Tsuyoshi Konuma, Erisa Harada, Kenji Sugase
- Organizer
  5^<th> Asia-Pacific NMR Symposium
- Place of Presentation
  Brisbane, Australia
- Data Source
  KAKENHI-PROJECT-24770106
[Presentation] Analysis of protein dynamics in living human cells2013
- Author(s)
  Kenji Sugase, Erisa Harada, Toshio Takahashi, Shoko Mori
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド、神戸
- Data Source
  KAKENHI-PLANNED-21113003
[Presentation] Mechanism of the distal regulation of substrate binding through intrinsic fluctuation in an enzyme2013
- Author(s)
  Kenji Sugase
- Organizer
  The 10th Korea-Japan Bilateral Symposium on Biological NMR
- Place of Presentation
  Seoul National University, Seoul, Korea
- Invited
- Data Source
  KAKENHI-PLANNED-21113003
[Presentation] Analysis of protein dynamics in living human cells2013
- Author(s)
  Kenji Sugase, Erisa Harada, Toshio Takahashi, Shoko Mori
- Organizer
  第36回分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24770106
[Presentation] 揺らぎが制御するヘム分解酵素反応の遠位効果2013
- Author(s)
  菅瀬謙治
- Organizer
  第14回若手NMR研究会
- Place of Presentation
  京都
- Invited
- Data Source
  KAKENHI-PROJECT-25650056
[Presentation] Elucidation of nonspecific DNA-binding mechanism by quantitative analysis of chemical shift changes2013
- Author(s)
  Tsuyoshi Konuma, Erisa Harada, Takashi Oda, Mamoru Sato, Kenji Sugase
- Organizer
  5^<th> Asia-Pacific NMR Symposium
- Place of Presentation
  Brisbane, Australia
- Data Source
  KAKENHI-PROJECT-24770106
[Presentation] 緩和分散差スペクトル法による混みあったNMRスペクトルの緩和分散データの解析2012
- Author(s)
  小沼剛、菅瀬謙治
- Organizer
  第51回 NMR討論会
- Place of Presentation
  名古屋市
- Year and Date
  2012-11-08
- Data Source
  KAKENHI-PLANNED-21113003
[Presentation] Elucidation of the DNA-binding dynamics of the transcription factor Oct3/4 POU homeodomain2012
- Author(s)
  Tsuyoshi Konuma, Erisa Harada, Kenji Sugase
- Organizer
  25th International Conference on Magnetic Resonance in Biological Systems
- Place of Presentation
  Lyon, France
- Data Source
  KAKENHI-PROJECT-24770106
[Presentation] 揺らぎから機能をどのように見るか2012
- Author(s)
  菅瀬謙治
- Organizer
  よこはまNMR構造生物学研究会第43回ワークショップ
- Place of Presentation
  理化学研究所横浜研究所交流棟ホール(神奈川)
- Year and Date
  2012-02-06
- Data Source
  KAKENHI-PLANNED-21113003
[Presentation] 揺らぎが制御するヘム分解酵素反応の遠位効果2012
- Author(s)
  原田、杉島、原田、野口、福山、菅瀬
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24770106
[Presentation] 動的構造解析による酵素ヘムオキシゲナーゼの機能発現メカニズムの解明2011
- Author(s)
  菅瀬謙治
- Organizer
  第17回創薬情報研究会
- Place of Presentation
  新大阪丸ビル新館(大阪)
- Year and Date
  2011-09-13
- Data Source
  KAKENHI-PLANNED-21113003
[Presentation] Stabilization of proteins by choline-O-sulfate during preparation and NMR measurement2011
- Author(s)
  Kaori Wakamatsu, Haimei Wang, Masahiko Takahashi, Kazuma Nakazawa, Mitsuhiko Yoshizawa, Tetsuro Demura, Kazuo Hosoda, Shin-ichi Terawaki, Nobukazu Nameki, Kenji Sugase
- Organizer
  The International Symposium on Nuclear Magnetic Resonance 2011
- Place of Presentation
  横浜大さん橋ホール
- Year and Date
  2011-11-17
- Data Source
  KAKENHI-PROJECT-21570108
[Presentation] Boosting Protein Dynamics Studies using Quantitative Non-Uniform Sampling (NUS) NMR2011
- Author(s)
  菅瀬謙治
- Organizer
  第50回NMR討論会
- Place of Presentation
  大さん橋ホール(神奈川)
- Year and Date
  2011-11-16
- Data Source
  KAKENHI-PLANNED-21113003
[Presentation] Stabilization of proteins by cholie-O-sulfate duing preparation and NMR measurement2011
- Author(s)
  K. Wakamatsu, H. Wang, M. Takahashi, K. Nakazawa, M. Yoshizawa, T. Demura, K. Hosoda, S. Teraw, N. Nameki, K. Sugase
- Organizer
  The International Symposium on Nuclear Magnetic Resonance 2011
- Place of Presentation
  横浜大さん橋ホール(神奈川県)
- Year and Date
  2011-11-15
- Data Source
  KAKENHI-PROJECT-21570108
[Presentation] NMRによるヘムオキシゲナーゼのヘム認識機構の解明2010
- Author(s)
  菅瀬謙治
- Organizer
  大阪大学蛋白質研究所セミナー
- Place of Presentation
  大阪大学蛋白質研究所(大阪府)
- Year and Date
  2010-07-30
- Data Source
  KAKENHI-PROJECT-21770126
[Presentation] 緩和分散解析用プログラムGLOVE2010
- Author(s)
  菅瀬謙治
- Organizer
  第49回NMR討論会
- Place of Presentation
  タワーホール船堀(東京)
- Year and Date
  2010-06-18
- Data Source
  KAKENHI-PLANNED-21113003
[Presentation] 蛋白質・ペプチドの溶液NMRへのスルホベタイン類の応用2010
- Author(s)
  若松馨, 王海梅, 五十嵐麗樹, 神谷歩, 高橋雅彦, 手塚福栄, 向瓏, 石井毅, 細田和男, 行木信一, 菅瀬謙治
- Organizer
  第49回NMR討論会
- Place of Presentation
  タワーホール船堀(東京都)
- Year and Date
  2010-11-15
- Data Source
  KAKENHI-PROJECT-21570108
[Presentation] オオムギのムギネ酸類・鉄錯体トランスポーターHvYS1における基質選択性に関与する膜外ループの解析2010
- Author(s)
  村田佳子,原田英理砂、菅瀬謙治、岩下孝
- Organizer
  第21回日本微量元素学会年会
- Place of Presentation
  京都大学百周年時計台記念館(京都)
- Data Source
  KAKENHI-PROJECT-21310148
[Presentation] NMRによるヘムオキシゲナーゼのヘム認識機構の解明2010
- Author(s)
  菅瀬謙治
- Organizer
  大阪大学蛋白質研究所セミナー
- Place of Presentation
  大阪大学蛋白質研究所(大阪府)
- Year and Date
  2010-07-30
- Data Source
  KAKENHI-PLANNED-21113003
[Presentation] 緩和分散解析用プログラムGLOVE2010
- Author(s)
  菅瀬謙治
- Organizer
  第49回NMR討論会
- Place of Presentation
  タワーホール船堀(東京)
- Year and Date
  2010-06-18
- Data Source
  KAKENHI-PROJECT-21770126
[Presentation] 動きの面から見た核内タンパク質の機能2010
- Author(s)
  菅瀬謙治
- Organizer
  ターゲットタンパク研究プログラム第3回研究交流会
- Place of Presentation
  東京大学(東京)
- Year and Date
  2010-03-04
- Data Source
  KAKENHI-PROJECT-21770126
[Presentation] 緩和分散解析用プログラムGLOVE2010
- Author(s)
  菅瀬謙治
- Organizer
  第49回NMR討論会
- Place of Presentation
  タワーホール船堀(東京)
- Year and Date
  2010-06-18
- Data Source
  KAKENHI-PUBLICLY-21107531
[Presentation] Fitting Relaxation Dispersion Data With A New Software Package GLOVE2010
- Author(s)
  菅瀬謙治
- Organizer
  XXIVth International Conference on Magnetic Resonance in Biological Systems
- Place of Presentation
  Cairns convention centre (Australia)
- Year and Date
  2010-08-24
- Data Source
  KAKENHI-PUBLICLY-21107531
[Presentation] NMRによる天然変性タンパク質の動的構造解析2010
- Author(s)
  菅瀬謙治
- Organizer
  第10回日本蛋白質科学会年会
- Place of Presentation
  札幌コンベンションセンター(北海道)
- Year and Date
  2010-06-18
- Data Source
  KAKENHI-PLANNED-21113003
[Presentation] Fluctuation and function of nuclear proteins2010
- Author(s)
  菅瀬謙治
- Organizer
  第48回日本生物物理学会年会
- Place of Presentation
  東北大学(岩手県)
- Year and Date
  2010-09-20
- Data Source
  KAKENHI-PROJECT-21770126
[Presentation] NMRによるヘムオキシゲナーゼのヘム認識機構の解明2010
- Author(s)
  菅瀬謙治
- Organizer
  大阪大学蛋白質研究所セミナー
- Place of Presentation
  大阪大学蛋白質研究所(大阪府)
- Year and Date
  2010-07-30
- Data Source
  KAKENHI-PUBLICLY-21107531
[Presentation] 動きの面から見た核内タンパク質の機能2010
- Author(s)
  菅瀬謙治
- Organizer
  ターゲットタンパク研究プログラム第3回研究交流会
- Place of Presentation
  東京大学(東京)
- Year and Date
  2010-03-04
- Data Source
  KAKENHI-PUBLICLY-21107531
[Presentation] Fluctuation and function of nuclear proteins2010
- Author(s)
  菅瀬謙治
- Organizer
  第48回日本生物物理学会年会
- Place of Presentation
  東北大学(岩手県)
- Year and Date
  2010-09-20
- Data Source
  KAKENHI-PUBLICLY-21107531
[Presentation] Fluctuation and function of nuclear proteins2010
- Author(s)
  菅瀬謙治
- Organizer
  第48回日本生物物理学会年会
- Place of Presentation
  東北大学、岩手
- Year and Date
  2010-09-20
- Invited
- Data Source
  KAKENHI-PLANNED-21113003
[Presentation] Fluctuation and function of nuclear proteins2010
- Author(s)
  菅瀬謙治
- Organizer
  第48回日本生物物理学会年会
- Place of Presentation
  仙台
- Year and Date
  2010-09-20
- Data Source
  KAKENHI-PROJECT-21770126
[Presentation] Fitting Relaxation Dispersion Data With A New Software Package GLOVE2010
- Author(s)
  菅瀬謙治
- Organizer
  XXIVth International Conference on Magnetic Resonance in Biological Systems
- Place of Presentation
  Cairns, Australia
- Year and Date
  2010-08-24
- Data Source
  KAKENHI-PROJECT-21770126
[Presentation] Effects of non-detergent sulfobetaines on protein dynamics2010
- Author(s)
  Kaori Wakamatau, Haimei Wang, Ayaka Matsui, Nobukazu Nameki, Kenji Sugase
- Organizer
  第48回日本生物物理学会年会
- Place of Presentation
  東北大学
- Year and Date
  2010-09-20
- Data Source
  KAKENHI-PROJECT-21570108
[Presentation] Fitting Relaxation Dispersion Data With A New Software Package GLOVE2010
- Author(s)
  菅瀬謙治
- Organizer
  XXIVth International Conference on Magnetic Resonance in Biological Systems
- Place of Presentation
  Cairns convention centre (Australia)
- Year and Date
  2010-08-24
- Data Source
  KAKENHI-PROJECT-21770126
[Presentation] Fitting Relaxation Dispersion Data With A New Software Package GLOVE2010
- Author(s)
  Sugase, K., Lansing, J.C. Wright, P.E.
- Organizer
  XXIVth International Conference on Magnetic Resonance in Biological Systems
- Place of Presentation
  Cairns convention centre, Australia
- Year and Date
  2010-08-24
- Data Source
  KAKENHI-PLANNED-21113003
[Presentation] NMRによる天然変性タンパク質の動的構造解析2010
- Author(s)
  菅瀬謙治
- Organizer
  第10回日本蛋白質科学会年会
- Place of Presentation
  札幌コンベンションセンター(北海道)
- Year and Date
  2010-06-18
- Data Source
  KAKENHI-PROJECT-21770126
[Presentation] NMRによる天然変性タンパク質の動的構造解析2010
- Author(s)
  菅瀬謙治
- Organizer
  第10回日本蛋白質科学会年会
- Place of Presentation
  札幌コンベンションセンター(北海道)
- Year and Date
  2010-06-18
- Data Source
  KAKENHI-PUBLICLY-21107531
[Presentation] Effects of NDSB, amyloid formation inhibitor, on protein structure2010
- Author(s)
  Haimei Wang, Mayu Enomoto, Nobukazu Nameki, Kenji Sugase, Kaori Wakamatsu
- Organizer
  5th International peptide symposium
- Place of Presentation
  京都国際会館
- Year and Date
  2010-12-04
- Data Source
  KAKENHI-PROJECT-21570108
[Presentation] 動きの面から見た核内タンパク質の機能2010
- Author(s)
  菅瀬謙治
- Organizer
  ターゲットタンパク研究プログラム第3回研究交流会
- Place of Presentation
  東京
- Year and Date
  2010-03-04
- Data Source
  KAKENHI-PROJECT-21770126
[Presentation] Fitting Relaxation Dispersion Data With A New Software Package GLOVE2010
- Author(s)
  菅瀬謙治
- Organizer
  XXIVth International Conference on Magnetic Resonance in Biological Systems
- Place of Presentation
  Cairns convention centre (Australia)
- Year and Date
  2010-08-24
- Data Source
  KAKENHI-PLANNED-21113003
[Presentation] 蛋白質・ペプチドの溶液NMRへのスルホベタイン類の応用2010
- Author(s)
  若松馨, 王海梅, 五十嵐麗樹, 神谷歩, 高橋雅彦, 手塚福栄, 向瓏, 石井毅, 細田和男, 行木信一, 菅瀬謙治
- Organizer
  第49回NMR討論会
- Place of Presentation
  タワーホール船堀
- Year and Date
  2010-11-15
- Data Source
  KAKENHI-PROJECT-21570108
[Presentation] 動きの面から見た核内タンパク質の機能2010
- Author(s)
  菅瀬謙治
- Organizer
  ターゲットタンパク研究プログラム第3回研究交流会
- Place of Presentation
  東京大学(東京)
- Year and Date
  2010-03-04
- Data Source
  KAKENHI-PLANNED-21113003
[Presentation] NMR による天然変性タンパク質の動的構造解析2010
- Author(s)
  菅瀬謙治
- Organizer
  第10回日本蛋白質科学会年会
- Place of Presentation
  札幌
- Year and Date
  2010-06-18
- Data Source
  KAKENHI-PROJECT-21770126
[Presentation] Fluctuation and function of nuclear proteins2010
- Author(s)
  菅瀬謙治
- Organizer
  第48回日本生物物理学会年会
- Place of Presentation
  東北大学(岩手県)
- Year and Date
  2010-09-20
- Data Source
  KAKENHI-PLANNED-21113003
[Presentation] NMR による天然変性タンパク質の動的構造解析2010
- Author(s)
  菅瀬謙治
- Organizer
  第10回日本蛋白質科学会年会
- Place of Presentation
  札幌コンベンションセンター、北海道
- Year and Date
  2010-06-18
- Invited
- Data Source
  KAKENHI-PLANNED-21113003
[Presentation] オオムギのムギネ酸類3価鉄錯体トランスポーターHvYS1の基質特異性に関わる膜外ループの解析2009
- Author(s)
  村田佳子,原田英理砂、菅瀬謙治、難波康祐、岩下孝
- Organizer
  第4回トランスポーター研究会
- Place of Presentation
  東京大学(東京)
- Data Source
  KAKENHI-PROJECT-21310148
[Presentation] 天然変性タンパク質の構造と機能の最前線2009
- Author(s)
  菅瀬謙治
- Organizer
  第49回生命科学夏の学校
- Place of Presentation
  神戸セミナーハウス(三田)
- Year and Date
  2009-08-30
- Data Source
  KAKENHI-PROJECT-21770126
[Presentation] Elucidation of protein-protein interactions by relaxation NMR spectroscopy2009
- Author(s)
  菅瀬謙治
- Organizer
  The 3rd APNMR Biannual Asia-Pacific NMR Symposium
- Place of Presentation
  Ramada hotel (Jeju, Korea)
- Year and Date
  2009-10-27
- Data Source
  KAKENHI-PLANNED-21113003
[Presentation] 天然変性タンパク質の構造と機能の最前線2009
- Author(s)
  菅瀬謙治
- Organizer
  第49回生命科学夏の学校
- Place of Presentation
  神戸セミナーハウス(三田)
- Year and Date
  2009-08-30
- Data Source
  KAKENHI-PLANNED-21113003
[Presentation] Elucidation of protein-protein interactions by relaxation NMR spectroscopy2009
- Author(s)
  菅瀬謙治
- Organizer
  The 3rd APNMR Biannual Asia-Pacific NMR Symposium
- Place of Presentation
  Jeju, Korea
- Year and Date
  2009-10-27
- Data Source
  KAKENHI-PROJECT-21770126
[Presentation] 天然変性状態と機能の相関2009
- Author(s)
  菅瀬謙治
- Organizer
  第32回日本分子生物学会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2009-12-11
- Data Source
  KAKENHI-PLANNED-21113003
[Presentation] 天然変性状態と機能の相関2009
- Author(s)
  菅瀬謙治
- Organizer
  第32回日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2009-12-11
- Data Source
  KAKENHI-PROJECT-21770126
[Presentation] 天然変性タンパク質の構造と機能の最前線2009
- Author(s)
  菅瀬謙治
- Organizer
  第49回生命科学夏の学校
- Place of Presentation
  神戸セミナーハウス(三田)
- Year and Date
  2009-08-30
- Data Source
  KAKENHI-PUBLICLY-21107531
[Presentation] Structural analysis of an outer membrane loop responsible for substrate specificity of Fe(III)-phytosiderophore transpoerters2009
- Author(s)
  原田英理砂、村田佳子、菅瀬謙治
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(横浜)
- Data Source
  KAKENHI-PROJECT-21310148
[Presentation] NDSB類が蛋白質のダイナミクスに及す効果2009
- Author(s)
  若松馨, 王海梅, 松井文香, 神谷歩, 加藤瀬里, 行木信一, 菅瀬謙治
- Organizer
  第48回NMR討論会
- Place of Presentation
  九州大学
- Year and Date
  2009-11-10
- Data Source
  KAKENHI-PROJECT-21570108
[Presentation] 天然変性状態と機能の相関2009
- Author(s)
  菅瀬謙治
- Organizer
  第32回日本分子生物学会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2009-12-11
- Data Source
  KAKENHI-PROJECT-21770126
[Presentation] Elucidation of protein-protein interactions by relaxation NMR spectroscopy2009
- Author(s)
  Sugase, K
- Organizer
  The 3rd APNMR Biannual Asia-Pacific NMR Symposium
- Place of Presentation
  Ramada hotel, Korea
- Year and Date
  2009-10-27
- Invited
- Data Source
  KAKENHI-PLANNED-21113003
[Presentation] 天然変性タンパク質の構造と機能の最前線2009
- Author(s)
  菅瀬謙治
- Organizer
  第49回生命科学夏の学校
- Place of Presentation
  三田
- Year and Date
  2009-08-30
- Data Source
  KAKENHI-PROJECT-21770126
[Presentation] 天然変性状態と機能の相関2009
- Author(s)
  菅瀬謙治
- Organizer
  第32回日本分子生物学会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2009-12-11
- Data Source
  KAKENHI-PUBLICLY-21107531
[Presentation] ムギネ酸類を介したイネ科植物の鉄取り込み機構2009
- Author(s)
  村田佳子、難波康祐、馬建鋒、菅瀬謙治、堀川学、岩下孝、楠本正一
- Organizer
  第51回天然有機化合物討論会
- Place of Presentation
  名古屋大学(名古屋)
- Data Source
  KAKENHI-PROJECT-21310148
[Presentation] NDSBか類蛋白質の & タイナミクスに及す効果2009
- Author(s)
  若松馨, 王海梅, 松井文香, 神谷歩, 加藤瀬里, 行木信一, 菅瀬謙治
- Organizer
  第48回NMR討論会
- Place of Presentation
  九州大学(福岡県)
- Year and Date
  2009-11-10
- Data Source
  KAKENHI-PROJECT-21570108
[Presentation] Elucidation of protein-protein interactions by relaxation NMR spectroscopy2009
- Author(s)
  菅瀬謙治
- Organizer
  The 3rd APNMR Biannual Asia-Pacific NMR Symposium
- Place of Presentation
  Ramada hotel(Jeju, Korea)
- Year and Date
  2009-10-27
- Data Source
  KAKENHI-PUBLICLY-21107531
[Presentation] オオムギのムギネ酸類・3価鉄錯体トランスポーターHvYS1の基質特異性の解析2009
- Author(s)
  村田佳子、原田英理砂、菅瀬謙治、岩下孝
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド(神戸)
- Data Source
  KAKENHI-PROJECT-21310148
[Presentation] Elucidation of protein-protein interactions by relaxation NMR spectroscopy2009
- Author(s)
  菅瀬謙治
- Organizer
  The 3rd APNMR Biannual Asia-Pacific NMR Symposium
- Place of Presentation
  Ramada hotel(Jeju, Korea)
- Year and Date
  2009-10-27
- Data Source
  KAKENHI-PROJECT-21770126
[Presentation] ヒト基本転写因子TFIIE alhpa酸性ドメインの動的構造解析2009
- Author(s)
  小松正史, 奥田昌彦, 長土居有隆, 菅瀬謙治, 西村善文
- Organizer
  第48回NMR討論会
- Place of Presentation
  九州大学医学部百年講堂(福岡県)
- Data Source
  KAKENHI-PLANNED-21113003
[Presentation] Structural dynamics of Sox2 upon binding to DNA
- Author(s)
  Kenji Sugase
- Organizer
  ICMRBS XXVI
- Place of Presentation
  Texas, USA
- Year and Date
  2014-08-24 – 2014-08-29
- Invited
- Data Source
  KAKENHI-PROJECT-25650056

1. 森本大智 (40746616)

# of Collaborated Projects: 3 results

# of Collaborated Products: 12 results
2. Walinda Erik (80782391)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
3. 吉田紀生 (10390650)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 山口毅 (80345917)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. AKASHI Satoko (10280728)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. MIZUGUCHI Mineyuki (30332662)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. NISHIMURA Yoshifumi (70107390)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. MURATA Yoshiko (60256047)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
9. NAMBA Kosuke (50414123)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. YAMAGAKI Tohru (40313209)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. MURATA Jun (90500794)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
12. ARAKI Ryoichi (00530841)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. WAKAMATSU Kaori (40222426)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
14. NAMEKI Nobukazu (80302959)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
15. HARADA ERISA (70541332)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
16. 関山直孝 (50758810)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 中村秀樹 (50435666)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 池田将 (20432867)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. MIZUTANI Akihiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. YAGI Maho

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 白川昌宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Sugase Kenji 菅瀬 謙治

SUGASE Kenji 菅瀬 謙治

菅瀬 謙治 スガセ ケンジ

Research Projects

Research Products

Co-Researchers

Investigation of molecular aggregation control mechanism by solution environment and creation of molecular design tools

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the mechanism of protein aggregation in flow by using Rheo-NMR and Rheo-MDPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

動的溶液科学の推進

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Atomic-level analysis of proteins responding to dynamic solution environments using NMRPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of analytical platform for proteins in electric field and its applicationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

NMR study on local structural fluctuations of double-stranded DNAPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the mechanism of amyloid fibrillation of alpha-synuclein starting from liquid-liquid phase separationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a new methodology for determining dissociation constants of proteins and drugs in cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Velocity imaging of turbulence flow using Rheo-NMRPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of the effects of crowded environment and shear force to proteins using Rheo-NMRPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Elucidation of the mechanism of amyloid fibrillation using Rheo-NMR and development of a new Rheo-NMR instrumentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Activation mechanism of ubiquitin ligase parkin by PINK1 and phosphorylated ubiquitinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Ultra-fast NMR measurement to analyze dynamics of Sox2 in cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Sugase Kenji 菅瀬謙治

SUGASE Kenji 菅瀬謙治

菅瀬謙治スガセケンジ

[Book] ＮＭＲによる有機材料分析とその試料前処理、データ解釈2021