Furuchi Takemitsu 古地壯光

… Alternative Names

FURUCHI Takemitsu 古地壯光

古地壮光フルチタケミツ

古地〓光フルチタケミツキゴウ

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Researcher Number	00302167
Other IDs
Affiliation (Current)	2025: 城西大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 城西大学, 薬学部, 教授 2010 – 2011: 北里大学, 薬学部, 准教授 2009: Kitasato University, 薬学部, 講師 2004 – 2007: 北里大学, 薬学部, 講師 2002: 北里大学, 薬学部, 助手 2001: Tohoku University, Graduate School of Pharmaceutical Sciences, Research Associate, 大学院・薬学研究科, 助手 1999 – 2000: 東北大学, 大学院・薬学研究科, 教務職員
Review Section/Research Field	Principal Investigator Biological pharmacy / Biological pharmacy / Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related Except Principal Investigator Public health/Health science / Biological Sciences / Basic Section 59040:Nutrition science and health science-related
Keywords	Principal Investigator PIMT / ラセミ化 / 異性化 / アスパラギン / アスパラギン酸 / 転写因子 / 薬剤耐性 / シスプラチン / 酵母 / StAR … More / テストステロン / D-アスパラギン酸 / protein repair enzyme / Racemization / Isomerization / Asparagine / Aspartate / タンパク質修復酵素 / 発現調節 / 修復 / タンパク質 / 分子生物学 … More Except Principal Investigator 酵母 / 耐性遺伝子 / シスプラチン / Cdc34 / GFAT / 転写因子 / 細胞老化 / MDL72527 / スペルミン / アミノ酸 / スペルミン酸化酵素 / ポリアミン / 老化 / Ubiquitin / Yeast / Resistance / Methylmercury / グルコサミン / 培養細胞 / 細胞内標的分子 / メチル水銀毒性 / グルコサミン6リン酸 / ユビキチン / 耐性 / メチル水銀 / Exon 3 / Promoter / Polymorphism / Kidney / Metallothionein / Cadmium / 遺伝子多型 / PCR-SSCP / エクソン3 / プロモーター異常 / 塩基配列異常 / 腎臓 / メタロチオネイン / カドミウム / Ydr259c / Cin5 / パラコート / Yap1 / 発現抑制 / マイトマイシンC / 高発現 Less

D-アスパラギン酸によるテストステロン産生促進機構の解析Principal Investigator
- Principal Investigator
  
  古地壯光
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Josai University
加齢によるスペルミン分解活性化機構解明と新規抗老化物質の創出
- Principal Investigator
  
  植村武史
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Josai University
Analysis of regulatory mechanisms of Protein L-isoaspartyl(D-aspartyl) O-methyltransferase(PIMT) gene expression.Principal Investigator
- Principal Investigator
  
  FURUCHI Takemitsu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kitasato University
Role of protein L-isoaspartyl(D-aspartyl)methyltransferase in cellular functionsPrincipal Investigator
- Principal Investigator
  
  FURUCHI Takemitsu
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kitasato University
蛋白質の異性化が細胞内情報伝達に及ぼす影響の解析Principal Investigator
- Principal Investigator
  
  古地壯光
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kitasato University
シスプラチンの細胞毒性発現に関与する蛋白質の同定とその機能解析
- Principal Investigator
  
  永沼章
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
酵母シスプラチン耐性因子Cin5、Ydr259c高発現による耐性護得機構の解析Principal Investigator
- Principal Investigator
  
  古地壯光
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kitasato University
  Tohoku University
シスプラチン耐性に関与するヒト細胞内因子の酵母を用いた検索
- Principal Investigator
  
  永沼章
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
Investigation of Target Molecules of Methylmercury Toxicity
- Principal Investigator
  
  NAGANUMA Akira
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Public health/Health science
- Research Institution
  Tohoku University
シスプラチン耐性に関与するヒト細胞内因子の酵母を用いた検索
- Principal Investigator
  
  NAGANUMA Akira
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Tohoku University
シスプラチン耐性因子の検索とその耐性獲得機構の解明Principal Investigator
- Principal Investigator
  
  古地壯光
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tohoku University
Mechanism of Individual Difference in Metallothionein Concentration in the Kidney
- Principal Investigator
  
  MIYAIRI Shinichi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Public health/Health science
- Research Institution
  Tohoku University

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All Journal Article Presentation Patent

[Journal Article] Inhibition of Polyamine Catabolism Reduces Cellular Senescence2023
- Author(s)
  Uemura Takeshi、Matsunaga Miki、Yokota Yuka、Takao Koichi、Furuchi Takemitsu
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 17 Pages: 13397-13397
- DOI
  10.3390/ijms241713397
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K11860
[Journal Article] Spatiotemporal localization of D-amino acid oxidase and D-aspartate oxidases during development in Caenorhabditis elegans2012
- Author(s)
  Saitoh Y, Katane M, Kawata T, Maeda K, Sekine M, Furuchi T, Kobuna H, Sakamoto T, Inoue T, Arai H, Nakagawa Y, Homma H
- Journal Title
  
  Mol Cell Biol
  
  Volume: 32(10) Issue: 10 Pages: 1967-1983
- DOI
  10.1128/mcb.06513-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590069, KAKENHI-PUBLICLY-23113707, KAKENHI-PROJECT-23227004, KAKENHI-PROJECT-24590090, KAKENHI-PROJECT-24790086
[Journal Article] Role of the active site residues arginine-216 and arginine-237 in the substrate specificity of mammalian D-aspartate oxidase2011
- Author(s)
  Katane M, Saitoh Y, Maeda K, Hanai T, Sekine M, Furuchi T, Homma H
- Journal Title
  
  Amino Acids
  
  Volume: 40(2) Issue: 2 Pages: 467-476
- DOI
  10.1007/s00726-010-0658-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590069
[Journal Article] Comparative characterization of three D-aspartate oxidases and one D-amino acid oxidase from Caenorhabditis elegans2010
- Author(s)
  Katane M, Saitoh Y, Seida Y, Sekine M, Furuchi T, Homma H
- Journal Title
  
  Chem Biodivers
  
  Volume: 7(6) Issue: 6 Pages: 1424-1434
- DOI
  10.1002/cbdv.200900294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590069
[Journal Article] Thiolactomycin inhibits D-aspartate oxidase : a novel approach to probing the active site environment2010
- Author(s)
  Katane M, Saitoh Y, Hanai T, Sekine M, Furuchi T, Koyama N, Nakagome I, Tomoda H, Hirono S, Homma H
- Journal Title
  
  Biochimie
  
  Volume: 92(10) Issue: 10 Pages: 1371-1378
- DOI
  10.1016/j.biochi.2010.06.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590069
[Journal Article] The role of protein L-isoaspartyl/D-aspartyl O-methyltransferase(PIMT) in intracellular signal transduction2010
- Author(s)
  Furuchi T, Sakurako K, Katane M, Sekine M, Homma H
- Journal Title
  
  Chem Biodivers
  
  Volume: 7(6) Issue: 6 Pages: 1337-1348
- DOI
  10.1002/cbdv.200900273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590069
[Journal Article] The role of protein L-isoaspartyl/D-aspartyl O-methyltransferase (PIMT) in intracellular signal transduction.2010
- Author(s)
  Furuchi, Takemitsu
- Journal Title
  
  Chem Biodivers.
  
  Volume: 7(6) Pages: 1337-1348
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590069
[Journal Article] Apoptotic inducers activate the release of D-aspartate through a hypotonic stimulus-triggered mechanism in PC12 cells2009
- Author(s)
  Furuchi T, Suzuki T, Sekine M, Katane M, Homma H
- Journal Title
  
  Arch Biochem Biophys
  
  Volume: 490(2) Issue: 2 Pages: 118-128
- DOI
  10.1016/j.abb.2009.08.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590069
[Journal Article] Apoptotic inducers activate the release of D-aspartate through a hypotonic stimulus-triggered mechanism in PC12 cells.2009
- Author(s)
  Furuchi, Takemitsu
- Journal Title
  
  Arch Biochem Biophys. 490(2)
  
  Pages: 118-128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590069
[Journal Article] Suppression of protein l-isoaspartyl(d-aspartyl)methyltransferase results in hyperactivation of EGF-stimulated MEK-ERK signaling in cultured mammalian cells2008
- Author(s)
  Kosugi, S., Furuchi, T., Katane, M., Sekine, M., Shirasawa, T., Homma, H
- Journal Title
  
  Biochem Biophys Res Commun 371(1)
  
  Pages: 22-27
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590070
[Journal Article] Cloning and functional characterization of Arabidopsis thaliana D-amino acid aminotransferase-D-aspartate behavior during germination2008
- Author(s)
  Funakoshi, M., Sekine, M., Katane, M., Furuchi, T., Yohda, M., Yoshikawa, T., Homma, H
- Journal Title
  
  FEBS J 275(6)
  
  Pages: 1188-1200
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590070
[Journal Article] The ubiquitin-conjugating enzymes, Ubc4 and Cdc34, mediate cadmium resistance in budding yeast through different mechanisms2008
- Author(s)
  Hwang, GW., Furuchi, T., Naganuma, A
- Journal Title
  
  Life Sci 82(23-24)
  
  Pages: 1182-1185
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590070
[Journal Article] Hyperactive mutants of mouse D : -aspartate oxidase : mutagenesis of the active site residue serine 3082008
- Author(s)
  Katane, M., Hanai, T., Furuchi, T., Sekine, M., Homma, H
- Journal Title
  
  Amino Acids (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590070
[Journal Article] Role of isomerized protein repair enzyme,PIMT,in cellular functions (Review)2007
- Author(s)
  Furuchi, Takemitsu
- Journal Title
  
  Yakugaku Zasshi 127
  
  Pages: 1927-1936
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590070
[Journal Article] Ubiquitin-conjugating enzyme Cdc34 mediates cadmium resistance in budding yeast through ubiquitination of the transcription factor Met42007
- Author(s)
  Hwang, GW., Furuchi, T., Naganuma, A
- Journal Title
  
  Biochem Biophys Res Commun 363(3)
  
  Pages: 873-878
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590070
[Journal Article] Caenorhabditis elegans has two genes encoding functional d-aspartate oxidases2007
- Author(s)
  Katane, M., Seida, Y., Sekine, M., Furuchi, T., Homma, H
- Journal Title
  
  FEBS J 274(1)
  
  Pages: 137-149
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590070
[Journal Article] Role of isomerized protein repair enzyme, PIMT, in cellular functions2007
- Author(s)
  Furuchi, T., Homma, H
- Journal Title
  
  Yakugaku Zasshi 127(12)
  
  Pages: 1927-1936
- NAID
  110006546568
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590070
[Journal Article] Molecular cloning of a cDNA encoding mouse D-aspartate oxidase and functional characterization of its recombinant proteins by site-directed mutagenesis2007
- Author(s)
  Katane, M., Furuchi, T., Sekine, M., Homma, H
- Journal Title
  
  Amino Acids 32(1)
  
  Pages: 69-78
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590070
[Journal Article] Endocytic Ark/Prk kinases play a critical role in adriamycin resistance in both yeast and mammalian cells2006
- Author(s)
  Takahashi, T., Furuchi, T., Naganuma, A
- Journal Title
  
  Cancer Res 66(24)
  
  Pages: 11932-11937
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590070
[Journal Article] Free D-aspartate in mammals.2005
- Author(s)
  Furuchi, Takemitsu
- Journal Title
  
  Biol Pharm Bull. 28(9)
  
  Pages: 1566-1570
- NAID
  110003666469
- Data Source
  KAKENHI-PROJECT-16790061
[Journal Article] Functions of yeast helicase Ssl2p that are essential for viability are also involved in protection from the toxicity of adriamycin2004
- Author(s)
  Furuchi, Takemitsu
- Journal Title
  
  Nucleic Acids Res. 32(8)
  
  Pages: 2578-2585
- Data Source
  KAKENHI-PROJECT-16790061
[Journal Article] Overexpression of Ss12p confers resistance to adriamycin and actinomycin D in Saccharomyces cerevisiae.2004
- Author(s)
  Furuchi, Takemitsu
- Journal Title
  
  Biochem Biophys Res Commun. 314(3)
  
  Pages: 844-848
- Data Source
  KAKENHI-PROJECT-16790061
[Patent] siRNA発現ベクター及びそれを用いて作製したPIMT発現抑制株2005
- Inventor(s)
  本間浩, 古地壯光, 小杉桜子
- Industrial Property Rights Holder
  学校法人北里学園
- Filing Date
  2005-04-08
- Acquisition Date
  2006-10-26
- Data Source
  KAKENHI-PROJECT-18590070
[Patent] siRNA発現ベクター及びそれを用いて作製したPIMT発現抑制株2005
- Inventor(s)
  本間浩, 古地壯光, 小杉桜子
- Industrial Property Rights Holder
  学校法人北里学園
- Industrial Property Number
  2005-112635
- Filing Date
  2005-04-08
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590070
[Presentation] 酸化ストレスによる皮膚ダメージにおけるポリアミンの役割2024
- Author(s)
  折井瑠海, 植村武史, 古地壯光
- Organizer
  日本ポリアミン学会　第14回年会
- Data Source
  KAKENHI-PROJECT-22K11860
[Presentation] ポリアミン代謝酵素阻害剤は細胞の老化を抑制する2023
- Author(s)
  松永美紀，植村武史，横田優香，高野友輔，高尾浩一，古地壯光
- Organizer
  日本ポリアミン学会第13回年会
- Data Source
  KAKENHI-PROJECT-22K11860
[Presentation] ホリアミン代謝が細胞老化に与える影響2023
- Author(s)
  松永美紀、横田優香、高尾浩一、植村武史、古地壯光
- Organizer
  日本薬学会　第143年会
- Data Source
  KAKENHI-PROJECT-22K11860
[Presentation] スペルミン酸化酵素SMOXの阻害による細胞老化抑制の可能性2023
- Author(s)
  植村武史、松永美紀、横田優香、折井瑠海、高尾浩一、古地壯光
- Organizer
  第96回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-22K11860
[Presentation] ポリアミン代謝酵素阻害剤は細胞の老化を抑制する2023
- Author(s)
  松永美紀、横田優香、高尾浩一、植村武史、古地壯光
- Organizer
  日本ポリアミン学会　第13回年会
- Data Source
  KAKENHI-PROJECT-22K11860
[Presentation] ポリアミン代謝が細胞老化に与える影響2023
- Author(s)
  松永美紀，横田優香，高野友輔，高尾浩一，古地壯光，植村武史
- Organizer
  日本薬学会　第143年会
- Data Source
  KAKENHI-PROJECT-22K11860
[Presentation] Aging associated change in polyamine metabolism2022
- Author(s)
  Takeshi Uemura, Yuka Yokota, Miki Matsunaga, Yoshihisa Akasaka, Koichi Takao, Hiroshi Ikegaya, Takemitsu Furuchi
- Organizer
  Sixth International Conference on Polyamines: Biochemical, Physiological and Clinical Perspectives
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K11860
[Presentation] 異性化タンパク質修復酵素PIMTの転写因子の同定2011
- Author(s)
  立石秀樹、古地壯光、原田怜、清水由香里、伊藤耕平、片根真澄、関根正恵、太田安隆、本間浩
- Organizer
  第7回D-アミノ酸研究会学術講演会
- Place of Presentation
  東京
- Year and Date
  2011-09-09
- Data Source
  KAKENHI-PROJECT-21590069
[Presentation] Protein L-isoaspartyl/D-aspartyl-o-methyltransferase (PIMT)の転写調節機構の解析2011
- Author(s)
  古地壯光
- Organizer
  第84回日本生化学会大会シンポジウム「D-アミノ酸の生化学-飛躍する新領域-」
- Place of Presentation
  京都
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-21590069
[Presentation] Protein L-isoaspartyl/D-aspartyl-o-methyltransferase(PIMT)の転写調節機構の解析2011
- Author(s)
  古地壯光、本間浩
- Organizer
  第84回日本生化学会大会(京都)シンポジウム
- Place of Presentation
  京都
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-21590069
[Presentation] Identification of the transcription factor(s) responsible for Protein L-isoaspartyl (D-aspartyl) O-methyltransferase (PIMT) gene expression2011
- Author(s)
  Furuchi, Takemitsu
- Organizer
  23rd Biennial Joint Meeting of the International Society for Neurochemistry (ISN) and the European Society for Neurochemistry (ESN)
- Place of Presentation
  アテネ、ギリシャ
- Year and Date
  2011-08-29
- Data Source
  KAKENHI-PROJECT-21590069
[Presentation] Identification of the transcription factor(s) responsible for Protein L-isoaspartyl(D-aspartyl) O-methyltransferase(PIMT) gene expression2011
- Author(s)
  Takemitsu Furuchi, Satoru Harada, Kohei Ito, Shimizu Yukari, Masumi Katane, Masae Sekine, Yasutaka Ohta, Hiroshi Homma
- Organizer
  23rd Biennial Joint Meeting of the International Society for Neurochemistry(ISN) and the European Society for Neurochemistry(ESN)
- Place of Presentation
  Athens, Greece
- Year and Date
  2011-08-29
- Data Source
  KAKENHI-PROJECT-21590069
[Presentation] FUNCTIONAL ANALYSIS OF THE PROTEIN L-ISOASPARTYL/D-ASPARTYL O-METHYLTRANSFERASE(PINT)GENE PROMOTER2010
- Author(s)
  Furuchi, Takemitsu
- Organizer
  OzBio2010
- Place of Presentation
  メルボルン,オーストラリア
- Year and Date
  2010-09-28
- Data Source
  KAKENHI-PROJECT-21590069
[Presentation] Protein L-isoaspartyl(D-aspartyl) O-methyltransferase(PIMT)の転写調節に関わる因子の探索2010
- Author(s)
  伊藤耕平、古地壯光、原田怜、清水由香里、片根真澄、関根正恵、太田安隆、本間浩
- Organizer
  第83回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-21590069
[Presentation] Protein L-isoaspartyl/D-aspartyl-o-methyltransferase(PIMT)の転写活性化に必須な領域の同定2010
- Author(s)
  原田怜、古地壯光、清水由香里、片根真澄、関根正恵、本間浩
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-21590069
[Presentation] 異性化タンパク質修復酵素PIMTの転写調節因子の検索2010
- Author(s)
  原田怜、古地壯光、清水由香里、伊藤耕平、片根真澄、関根正恵、太田安隆、本間浩
- Organizer
  第6回D-アミノ酸研究会学術講演会
- Place of Presentation
  富山
- Year and Date
  2010-09-18
- Data Source
  KAKENHI-PROJECT-21590069
[Presentation] Characterization of the promoter region of the protein L-isoaspartyl/D-aspartyl O-methyltransferase(PIMT) gene2009
- Author(s)
  Yukari Shimizu, Takemitsu Furuchi, Sakurako Kosugi, Masumi Katane, Masae Sekine, Hiroshi Homma
- Organizer
  The first international conference of D-amino acid research
- Place of Presentation
  Awaji, Hyogo
- Year and Date
  2009-07-03
- Data Source
  KAKENHI-PROJECT-21590069
[Presentation] Simple high-performance liquid chromatography-fluorescence detection method to measure protein L-isoaspartyl/D-aspartyl O-methyltransferase activity in cell lysates.2009
- Author(s)
  Furuchi, Takemitsu
- Organizer
  21^<st> IUBMB and 12^<th> FAOBMB International Congress of Biochemistry and Molecular Biology
- Place of Presentation
  上海
- Data Source
  KAKENHI-PROJECT-21590069
[Presentation] Protein L-isoaspartyl/D-aspartyl methyltransferase(PIMT)プロモーターの転写制御に関わる転写因子の探索2009
- Author(s)
  清水由香里、古地壯光、原田怜、小杉桜子、片根真澄、関根正恵、本間浩
- Organizer
  第53回日本薬学会関東支部大会
- Place of Presentation
  坂戸
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-21590069
[Presentation] Simple high-performance liquid chromatography-fluorescence detection method to measure protein L-isoaspartyl/D-aspartyl O-methyltransferase activity in cell lysates2009
- Author(s)
  Takemitsu Furuchi, Sakurako Kosugi, Tsukasa Egawa, Keiko Ohno, Masae, Sekine, Masumi Katane, Hiroshi Homma
- Organizer
  21th IUBMB and 12th FAOBMB International congress of biochemistry and molecular biology
- Place of Presentation
  Shanghai, China
- Data Source
  KAKENHI-PROJECT-21590069
[Presentation] Analysis of mechanisms of EDF-triggered hyperactivation of ERK in L-isoaspartyl/D-aspartyl O-methyltransferase(PIMT)-knockdown cells.2009
- Author(s)
  Takemitsu Furuchi, Sakurako Kosugi, Satoru Harada, Masumi Katane, Masae Sekine, Hiroshi Homma
- Organizer
  The first international conference of D-amino acid research
- Place of Presentation
  Awaji, Hyogo
- Year and Date
  2009-07-02
- Data Source
  KAKENHI-PROJECT-21590069
[Presentation] Analysis of mechanisms of EGF-triggered hyperactivation of ERK in L-isoasparty 1/D-aspartyl O-methyltransferase(PIMT)-knockdown cells2009
- Author(s)
  Furuchi, Takemitsu
- Organizer
  The 1^<st> International Conference of D-Amino Acid Research
- Place of Presentation
  淡路
- Year and Date
  2009-07-02
- Data Source
  KAKENHI-PROJECT-21590069
[Presentation] Protein L-isoaspartyl/D-aspartyl methyltransferase(PIMT)の転写調節機構の解析2007
- Author(s)
  古地壯光
- Organizer
  日本生化学、日本分子生物学会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-12
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590070
[Presentation] 異性化タンパク質修復酵素PIMTの細胞機能における役割2007
- Author(s)
  古地壯光
- Organizer
  日本薬学会第127年会
- Place of Presentation
  富山
- Year and Date
  2007-03-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590070
[Presentation] Role of isomerized protein repair enzyme, PIMT, in cellular functions2007
- Author(s)
  Furuchi, T
- Organizer
  The 127th Annual Meeting of the Pharmaceutical Society of Japan
- Place of Presentation
  Toyama
- Year and Date
  2007-03-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590070
[Presentation] Protein L-isoaspartyl/D-aspartyl methyltransferase(PIMT)の転写調節機構の解析2007
- Author(s)
  古地壯光
- Organizer
  第80回日本生化学会大会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-12-12
- Data Source
  KAKENHI-PROJECT-18590070
[Presentation] Mechanisms of transcriptional regulation of Protein L-isoaspartyl/D-aspartyl methyltransferase gene in HEK293 cells2007
- Author(s)
  Furuchi, T
- Organizer
  The 80th Annual meeting of the Japanese Biochemical Society
- Place of Presentation
  Yokohama
- Year and Date
  2007-12-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590070

1. NAGANUMA Akira (80155952)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
2. MIURA Nobuhiko (20229644)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. MIYAIRI Shinichi (50209855)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 植村武史 (50401005)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
5. 小黒明広 (00292508)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 高尾浩一 (70337484)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results

Furuchi Takemitsu 古地 壯光

FURUCHI Takemitsu 古地 壯光

古地 壮光 フルチ タケミツ

古地 〓光 フルチ タケミツキゴウ

Research Projects

Research Products

Co-Researchers

D-アスパラギン酸によるテストステロン産生促進機構の解析Principal Investigator

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加齢によるスペルミン分解活性化機構解明と新規抗老化物質の創出

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Analysis of regulatory mechanisms of Protein L-isoaspartyl(D-aspartyl) O-methyltransferase(PIMT) gene expression.Principal Investigator

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Role of protein L-isoaspartyl(D-aspartyl)methyltransferase in cellular functionsPrincipal Investigator

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蛋白質の異性化が細胞内情報伝達に及ぼす影響の解析Principal Investigator

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シスプラチンの細胞毒性発現に関与する蛋白質の同定とその機能解析

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酵母シスプラチン耐性因子Cin5、Ydr259c高発現による耐性護得機構の解析Principal Investigator

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シスプラチン耐性に関与するヒト細胞内因子の酵母を用いた検索

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Investigation of Target Molecules of Methylmercury Toxicity

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シスプラチン耐性に関与するヒト細胞内因子の酵母を用いた検索

Principal Investigator

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シスプラチン耐性因子の検索とその耐性獲得機構の解明Principal Investigator

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Mechanism of Individual Difference in Metallothionein Concentration in the Kidney

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[Journal Article] Inhibition of Polyamine Catabolism Reduces Cellular Senescence2023

Author(s)

Furuchi Takemitsu 古地壯光

FURUCHI Takemitsu 古地壯光

古地壮光フルチタケミツ

古地〓光フルチタケミツキゴウ