IIJIMA Mikio 飯島幹雄

Researcher Number	00305111
Other IDs
Affiliation (based on the past Project Information) *help	2019 – 2021: 鹿児島大学, 医歯学域医学系, 助教 2015 – 2016: 鹿児島大学, 医歯学域医学系, 助教 2011 – 2014: 鹿児島大学, 医歯(薬)学総合研究科, 助教 2012: 鹿児島大学, 医歯学総合研究科, 助教 2009: 鹿児島大学, 大学院・歯学総合研究科, 助教 … More 2007 – 2009: Kagoshima University, 大学院・医歯学総合研究科, 助教 2006: Kagoshima University, Graduate School of Medical and Dental Sciences, Research Associate, 大学院医歯学総合研究科, 助手 2003 – 2005: Kagoshima University, Graduate School of Medical and Dental Sciences, Research Associate, 大学院・医歯学総合研究科, 助手 1998 – 2002: 鹿児島大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Basic Section 48030:Pharmacology-related / General medical chemistry / Pathological medical chemistry / Pharmacology in pharmacy / Laboratory medicine / Laboratory animal science Except Principal Investigator Human genetics / Human genetics / Pathological medical chemistry / Environmental physiology(including physical medicine and nutritional physiology) / Environmental physiology (including Physical medicine and Nutritional physiology)
Keywords	Principal Investigator SLC25A13 / aspartate glutamate carrier / citrin / mitochondria / citrullinemia / SLC25A12 / aralar / シトルリン血症 / ミトコンドリア / アスパラギン酸・グルタミン酸輸送体 … More / Wnt-5a / MMP / RYK / Wnt / 浸潤能 / MMP-2 / 受容体 / 浸潤性 / グリオーマ / cytochrome c / 成人発症II型シトルリン血症 / Aspartate glutamate carrier / Citrin / 細胞死 / チトクロームC / Ca-dependent mitochondrial solute carrier / glutamate carrier / aspartate / 新規受容体 / デスアシルグレリン / イムノクロマト法 / 骨 / 脳・神経 / アスパラギン酸グルタミン酸輸送体 … More Except Principal Investigator SLC25A13 / citrin / NADH shuttle / aspartate-glutamate carrier / Citrin / Argininosuccinate Synthetase / Malate Aspartate Shuttle / Aspartate Glutamate Carrier / Octn2 / PDK4 / 摂食調節 / glycerophosphate shuttle / malate-aspartate shuttle / 胆汁うっ滞性新生児肝炎(NICCD) / 成人発症II型シトルリン血症(CTLN2) / glycerol phosphate shuttle / malaie-aspartate shuttle / cholestatic neonatal hepatitis / adult-onset type II citrullinemia / Hepatic Cholestatic Jaundice / Neonatal Hepatitis / Adult-onset type II citrullinemia / 遺伝子診断 / urea cycle / 高アンモニア血症 / argininosuccinate synthetase / 新生児肝内胆汁うっ滞症 / II型シトルリン血症 / aspartate glutamate carrier / Urea cycle / Argininosuccinate synthetase / 肝内胆汁うつ滞症 / Aspartate glutamate carrier / 肝内胆汁うっ滞性黄疸 / 新生児肝炎 / 成人発症II型シトルリン血症 / Long-chain fatty acid / Juvenile visceral steatosis (JVS) mice / CDV (carnitine deficiency-associated genes) / Carnitine deficiency / Cardiac hypertrophy / カルニチン膜輸送体 / カルニチン欠乏 / CDV-3 / CDV-1 / 心肥大 / JVSマウス / カルチニン欠乏 / シグナル伝達 / 受容体 / デスアシルグレリン Less

Base construction for the development of therapeutic strategies for targeting the invasiveness in malignant gliomaPrincipal Investigator
- Principal Investigator
  
  IIJIMA Mikio
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Kagoshima University
Research for a novel regulatory mechanism of appetite via a des-acyl ghrelin receptorPrincipal Investigator
- Principal Investigator
  
  IIJIMA Mikio
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Kagoshima University
Analysis of signaling pathway of adropin and augurin regulating appetite
- Principal Investigator
  
  Ueda Masahiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Environmental physiology(including physical medicine and nutritional physiology)
- Research Institution
  Kagoshima University
Development and clinical application of the immunochromatography for a citrin proteinPrincipal Investigator
- Principal Investigator
  
  IIJIMA Mikio
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Kagoshima University
Identification and characterization of desacyl-ghrelin
- Principal Investigator
  
  UEDA Masahiro
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Environmental physiology (including Physical medicine and Nutritional physiology)
- Research Institution
  Kagoshima University
Molecular genetics of citrin deficiency and search for the genetic and/or environmental factor(s) concerned with onset of various symptoms
- Principal Investigator
  
  KOBAYASHI Keiko
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human genetics
- Research Institution
  Kagoshima University
Bone abnormalities and unilateral eye deterioration in aspartate-glutamate carrier deficient micePrincipal Investigator
- Principal Investigator
  
  IIJIMA Mikio
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  Kagoshima University
Molecular genetics of citrin deficiency and search for the factor(s) and mechanism of adult-onset type II citrullinemia onset
- Principal Investigator
  
  KOBAYASHI Keiko
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human genetics
- Research Institution
  Kagoshima University
Is mitochondria aberration initiated by mutated citrin correlated with cell death?Principal Investigator
- Principal Investigator
  
  LIJIMA Mikio
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Kagoshima University
Molecular Genetics and Pathophysiology of Adult-Onset Type II Citrullinemia
- Principal Investigator
  
  KOBAYASHI Keiko
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human genetics
- Research Institution
  Kagoshima University
Functional analysis of novel gene products, citrin and aralarPrincipal Investigator
- Principal Investigator
  
  IIJIMA Mikiko
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kagoshima University
Structure and function of novel genes which differentially expressed in cardiac hypertrophy of carnitine deficiency
- Principal Investigator
  
  SAHEKI Takeyori
- Project Period (FY)
  1998 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kagoshima University

All 2014 2013 2012 2011 2009 2008 2007 2006 2005 2004

All Journal Article Presentation

[Journal Article] Regulation of IL-6 and IL-8 production by reciprocal cell-to-cell interactions between tumor cells and stromal fibroblasts through IL-1α in ameloblastoma Biochemical and Biophysical Research Communications2014
- Author(s)
  Takao Fuchigami, Toshiro Kibe, Hirofumi Koyama, Shosei Kishida, Mikio Iijima, Yoshiaki Nishizawa, Hiroshi Hijioka, Tomomi Fujii, Masahiro Ueda, Norifumi Nakamura, Tohru Kiyono, Michiko Kishida
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 451 Issue: 4 Pages: 491-496
- DOI
  10.1016/j.bbrc.2014.07.137
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14J03262, KAKENHI-PROJECT-26463019, KAKENHI-PROJECT-26670114
[Journal Article] A novel ameloblastoma cell line (AM-3) secretes MMP-9 in response to Wnt-3a and induces osteoclastogenesis2013
- Author(s)
  Kibe T, Fuchigami T, Kishida M, Iijima M, Ishihata K, Hijioka H, Miyawaki A, Semba I, Nakamura N, Kiyono T, Kishida S
- Journal Title
  
  Oral Surg Oral Med Oral Pathol Oral Radiol
  
  Volume: 115(6) Issue: 6 Pages: 780-8
- DOI
  10.1016/j.oooo.2013.03.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592241, KAKENHI-PROJECT-23659124, KAKENHI-PROJECT-24659900
[Journal Article] Subcellular localization and putative role of VPS13A/chorein in dopaminergic neuronal cells2012
- Author(s)
  Hayashi T., et al
- Journal Title
  
  Biochem.Biophys.Res.Commun.
  
  Volume: 419巻 Issue: 3 Pages: 511-516
- DOI
  10.1016/j.bbrc.2012.02.047
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590341, KAKENHI-PROJECT-23390291, KAKENHI-PROJECT-23659124, KAKENHI-PROJECT-23659568
[Journal Article] Immortalization and characterization of normal oral epithelial cells without using HPV and SV40 genes2011
- Author(s)
  Toshiro Kibe, Michiko Kishida, Masayuki Kamino, Mikio Iiima, Lin Clen, Mika Habu, Akihiko Miyawaki, Hiroshi Hijioka, Norifumi Nakamura, Tohru Kiyono, Shosei Kishida
- Journal Title
  
  Oral Science International
  
  Volume: 8(1) Issue: 1 Pages: 20-28
- DOI
  10.1016/s1348-8643(11)00009-7
- NAID
  10030270663
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592929, KAKENHI-PROJECT-23659124
[Journal Article] Neonatal intrahepatic cholestasis caused by citrin deficiency (NICCD) as a cause of liver disease in infants in the UK.2009
- Author(s)
  Hutchin T, Iijima M, (他10名、8番目)
- Journal Title
  
  J Inherit. Metab. Dis.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500365
[Journal Article] Primary liver carcinoma exhibiting dual hepatocellular-biliary epithelial differentiations associated with citrin deficiency: a case report.2008
- Author(s)
  Soeda J, Yazaki M, Nakata T, Miwa S, Ikeda S, Hosoda W, Iijima M, Kobayashi K, Saheki T, Kojiro M, Miyagawa S
- Journal Title
  
  J Clin Gastroenterol 42(7)
  
  Pages: 855-860
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390096
[Journal Article] Identification of 13 novel mutations including a retrotransposal insertion in SLC25A13 gene and frequency of 30 mutations found in patients with citrin deficiency.2008
- Author(s)
  Tabata A, Sheng J-S, Ushikai M, Song Y-Z, Gao H-Z, Lu Y-B, Okumura F, Iijima M, Mutoh K, Kishida S, Saheki T, Kobayashi K
- Journal Title
  
  J Hum Genet 53(6)
  
  Pages: 534-545
- NAID
  80019634107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390096
[Journal Article] Ca2+ activation kinetics of the two aspartate-glutamate mitochondrial carriers, aralar and citrin : role in the heart malate-aspartate NADH shuttle.2007
- Author(s)
  Contreras L, Gomez-Puertas P, Iijima M, Kobayashi K, Saheki T, Satrustegui J.
- Journal Title
  
  J Biol Chem 282 (10)
  
  Pages: 7098-7106
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390100
[Journal Article] Citrin/mitochondrial glycerol-3-phosphate dehydrogenase double knock-out mice recapitulate features of human citrin deficiency.2007
- Author(s)
  Saheki T, Iijima M, Li MX, Kobayashi K, Horiuchi M, Ushikai M, Okumura F, Meng XJ, Inoue I, Tajima A, Moriyama M, Eto K, Kadowaki T, Sinasac DS, Tsui L-C, Tsuji M, Okano A, Kobayashi T
- Journal Title
  
  J Biol Chem 282(34)
  
  Pages: 25041-25052
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390096
[Journal Article] Ca2+ activation kinetics of the two aspartate-glutamate mitochondrial carriers aralar and citrin: Role in heart malate-aspartate NADH shuttle.2007
- Author(s)
  Contreras L, Gomez-Peurtas P, Iijima M, Kobayashi K, Saheki T, Satrustegui J
- Journal Title
  
  J. Biol. Chem. 282
  
  Pages: 7098-7196
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500365
[Journal Article] Citrin/mitochondrial glycerol-3-phosphate dehydrogenase double knock-out mice recapitulate features of human citrin deficiency.2007
- Author(s)
  Saheki T, Iijima M, Li MX, Kobayashi K, Horiuchi M, Ushikai M, Okumura F, Meng XJ, Inoue I, Tajima A, Moriyama M, Eto K, Kadowaki T, Sinasac DS, Tsui LC, Tsuji M, Okano A, Kobayashi T
- Journal Title
  
  J. Biol. Chem. 282
  
  Pages: 25041-25052
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500365
[Journal Article] Citrin deficiency : a novel cause of failure to thrive that responds to a high protein, low carbohydrate diet.2007
- Author(s)
  Dimmock D, Kobayashi K, Iijima M, Tabata A, Wong LJ, Saheki T, Lee B, Scaglia F.
- Journal Title
  
  Pediatrics 119 (3)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390100
[Journal Article] Ca^<2+> activation kinetics of the two aspartate-glutamate mitochondrial carriers aralar and citrin: Role in heart malate-aspartate NADH shuttle.2007
- Author(s)
  Contreras L, Gomez-Peurtas P, Iijima M, Kobayashi K, Saheki T, Satrustegui J
- Journal Title
  
  J. Biol. Chem. 282
  
  Pages: 7098-7106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500365
[Journal Article] Primary liver carcinoma exhibiting dual hepatocellular-biliary epithelial differentiations associated with citrin deficiency : A case report and review of the literature.2007
- Author(s)
  Soeda J, Yazaki M, Nakata T, Miwa S, Ikeda S, Hosoda W, Iijima M, Kobayashi K, Saheki T, Kojiro M, Miyagawa S.
- Journal Title
  
  J Clin Gastroenterol (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390100
[Journal Article] Citrin/mitochondrial glycerol-3-phosphate dehydrogenase double knock-out mice recapitulate features of human citrin deficiency.2007
- Author(s)
  Saheki T, Iijima M, (他6名、2番目)
- Journal Title
  
  J. Biol. Chem. 282
  
  Pages: 25041-25052
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500365
[Journal Article] Analysis of citrin protein in lymphocytes.2007
- Author(s)
  Tokuhara D, Iijima M, Tamamori A, Ohura T, Takaya J, Maisawa S, Kobayashi K, Saheki T, Yamano T, Okano Y. Novel diagnostic approach to citrin deficiency
- Journal Title
  
  Mol Genet Metab 90 (1)
  
  Pages: 30-36
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390100
[Journal Article] Essential role of aralar in the transduction of small Ca2+ signals to neuronal mitochondria.2006
- Author(s)
  Pardo B, Contreras L, Serrano A, Ramos M, Kobayashi K, Iijima M, Saheki T, Satrustegui J.
- Journal Title
  
  J Biol Chem 281 (2)
  
  Pages: 1039-1047
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390100
[Journal Article] Pathophysiology of citrin deficiency.2006
- Author(s)
  Saheki T, Kobayashi K, Iijima M, Li MX, Horiuchi M, Tabata A, Lu YB, Ushikai M, Terashi M, Moriyama M.
- Journal Title
  
  Hepatic Encephalopathy and Nitrogen Metabolism (eds. Haussinger D, Kircheis G, Schliess F) (Springer Science)
  
  Pages: 320-328
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390100
[Journal Article] <Review> Citrin deficiency. (Japanese)2006
- Author(s)
  Kobayashi K, Iijima M, Ushikai M, Ikeda S, Saheki T.
- Journal Title
  
  J Jpn Pediatr Soc 110 (8)
  
  Pages: 1047-1059
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390100
[Journal Article] Pyruvate ameliorates the defect in ureogenesis from ammonia in citrin-deficient mice.2006
- Author(s)
  Moriyama M, Li MX, Kobayashi K, Sinasac DS, Kannan Y, Iijima M, Horiuchi M, Tsui L-C, Tanaka M, Nakamura Y, Saheki T.
- Journal Title
  
  J Hepatol 44 (5)
  
  Pages: 930-938
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390100
[Journal Article] Metabolic derangements in deficiency of citrin, a liver-type mitochondrial aspartate-glutamate carrier.2005
- Author(s)
  Saheki T, Kobayashi K, Iijima M, Moriyama M, Yazaki M, Takei Y, Ikeda S.
- Journal Title
  
  Hepatol Res 33 (2)
  
  Pages: 181-184
- NAID
  10016809437
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390100
[Journal Article] Reduced N-acetylaspartate levels in mice lacking aralar, a brain- and muscle-type mitochondrial aspartate-glutamate carrier.2005
- Author(s)
  Jalil MA, Begum L, Contreras L, Pardo B, Iijima M, Li MX, Ramos M, Marmol P, Horiuchi M, Shimotsu K, Nakagawa S, Okubo A, Sameshima M, Isashiki Y, del Arco A, Kobayashi K, Satrustegui J, Saheki T.
- Journal Title
  
  J Biol Chem 280 (35)
  
  Pages: 31333-31339
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390100
[Journal Article] Frequency and distribution in East Asia of 12 mutations identified in the SLC25A13 gene of Japanese patients with citrin deficiency.2005
- Author(s)
  Lu YB, Kobayashi K, Ushikai M, Tabata A, Iijima M, Li MX, Lei L, Kawabe K, Taura S, Yang YL, Liu T-T, Chiang S-H, Hsiao K-J, Lau Y-L, Tsui L-C, Lee DH, Saheki T.
- Journal Title
  
  J Hum Genet 50 (7)
  
  Pages: 338-346
- NAID
  40006831555
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390100
[Journal Article] Slc25a13-knockout mice harbor metabolic deficits but fail to display hallmarks of adult-onset type II citrullinemia.2004
- Author(s)
  Sinasac DS, Moriyama M, Jalil MA, Begum L, Li MX, Iijima M, Horiuchi M, Robinson BH, Kobayashi K, Saheki T, Tsui L-C.
- Journal Title
  
  Mol Cell Biol 24 (2)
  
  Pages: 527-536
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390100
[Journal Article] Adult-onset type II citrullinemia and idiopathic neonatal hepatitis caused by citrin deficiency : involvement of the aspartate glutamate carrier for urea synthesis and maintenance of the urea cycle.2004
- Author(s)
  Saheki T, Kobayashi K, Iijima M, Horiuchi M, Begum L, Jalil MA, Li MX, Lu YB, Ushikai M, Tabata A, Moriyama M, Hsiao K-J, Yang YL.
- Journal Title
  
  Mol Genet Metab 81
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390100
[Presentation] Citrin/mGPDHダブルKOマウスを用いるシトリン欠損症の治療法の開発2008
- Author(s)
  佐伯武頼, 小林圭子, 飯島幹雄.
- Organizer
  第50回日本先天代謝異常学会総会・第7回アジア先天代謝異常学会
- Place of Presentation
  米子コンベンションセンター(米子)
- Data Source
  KAKENHI-PROJECT-19500365
[Presentation] Citrin/mGPDHダブルKOマウスを用いるシトリン欠損症の治療法の開発2008
- Author(s)
  佐伯武頼, 小林圭子, 飯島幹雄
- Organizer
  第50回日本先天代謝異常学会総会・第7回アジア先天代謝異常学会
- Place of Presentation
  米子
- Data Source
  KAKENHI-PROJECT-19500365
[Presentation] 国内外のシトリン欠損症におけるSLC25A13変異と頻度2007
- Author(s)
  小林圭子, 牛飼美晴, 盛建勝, 宋元宗, 奥村史彦, 池田さやか, 飯島幹雄, 佐伯武頼
- Organizer
  日本人類遺伝学会第52回大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19390096

1. KOBAYASHI Keiko (70108869)

# of Collaborated Projects: 6 results

# of Collaborated Products: 17 results
2. SAHEKI Takeyori (10056070)

# of Collaborated Projects: 6 results

# of Collaborated Products: 17 results
3. KISHIDA Shosei (50274064)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
4. KISHIDA Michiko (40274089)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
5. INUI Akio (80168418)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. NAKAGAWA Shiro (70073666)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. UEDA Masahiro (00448573)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. KOYAMA Hirofumi (40709656)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. KATO Ikuo (70509843)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. HORIUCHI Masahisa (50264403)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 安田いづみ (10305112)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. ISHIDA Takayuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. HIJIOKA Hiroshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
14. 宮脇昭彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 中村典史

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
16. 清野透

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

IIJIMA Mikio 飯島 幹雄

Research Projects

Research Products

Co-Researchers

Base construction for the development of therapeutic strategies for targeting the invasiveness in malignant gliomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Research for a novel regulatory mechanism of appetite via a des-acyl ghrelin receptorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of signaling pathway of adropin and augurin regulating appetite

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development and clinical application of the immunochromatography for a citrin proteinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification and characterization of desacyl-ghrelin

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular genetics of citrin deficiency and search for the genetic and/or environmental factor(s) concerned with onset of various symptoms

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Bone abnormalities and unilateral eye deterioration in aspartate-glutamate carrier deficient micePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular genetics of citrin deficiency and search for the factor(s) and mechanism of adult-onset type II citrullinemia onset

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Is mitochondria aberration initiated by mutated citrin correlated with cell death?Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular Genetics and Pathophysiology of Adult-Onset Type II Citrullinemia

Principal Investigator

Project Period (FY)

Research Category

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Functional analysis of novel gene products, citrin and aralarPrincipal Investigator

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Structure and function of novel genes which differentially expressed in cardiac hypertrophy of carnitine deficiency

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[Journal Article] Regulation of IL-6 and IL-8 production by reciprocal cell-to-cell interactions between tumor cells and stromal fibroblasts through IL-1α in ameloblastoma Biochemical and Biophysical Research Communications2014

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IIJIMA Mikio 飯島幹雄