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Higuchi Hidetoshi  樋口 豪紀

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HIGUCHI Hidetoshi  樋口 豪紀

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Researcher Number 00305905
Affiliation (Current) 2025: 酪農学園大学, 獣医学群, 教授
Affiliation (based on the past Project Information) *help 2014 – 2023: 酪農学園大学, 獣医学群, 教授
2014 – 2015: 酪農学園大学, 獣医学部, 教授
2012 – 2013: 酪農学園大学, 獣医学群, 准教授
2007 – 2013: Rakuno Gakuen University, 獣医学部, 准教授
2012: 酪農学園大学, 獣医学群獣医学類, 准教授
2000 – 2004: 酪農学園大学, 獣医学部, 講師
1999: 酪農学園大学, 獣医学部, 助手
Review Section/Research Field
Principal Investigator
Applied veterinary science / Basic Section 42020:Veterinary medical science-related / Applied veterinary science / Veterinary medical science
Except Principal Investigator
Veterinary medical science / Clinical veterinary science / Environmental impact assessment / Animal production science / Applied veterinary science / Applied veterinary science
Keywords
Principal Investigator
ウシ / マイコプラズマ / 乳腺上皮細胞 / 乳房炎 / 好中球 / サイトカイン / 免疫回避 / Mycoplasma bovis / 感染防御 / ケラチン … More / セラミド / 蹄 / 細胞内情報伝達系 / 気管上皮 / 呼吸器感染症 / 気管上皮細胞 / 免疫応答性 / 滑膜組織 / サイトカイン遺伝子 / M.bovis / 細胞内侵入性 / 滑膜細胞 / 病態形成メカニズム / 関節炎 / リンパ球 / M. bovis / 単核急 / マイコプラズマ / 治療技術 / ファージ / 高度治療技術 / PBMC / 三次元培養 / 免疫 / 黄色ブドウ球菌 / 情報伝達系 / 乳腺細胞 / マクロファージ / ラクトフェリン / 乳房炎病原細菌 / 白血球 / ウシ乳房炎 / 活性酸素生成能 / 蹄疾患 / ビオチン / サイトケラチン / ケラチノサイト / 角質 / 好中球機能 / 新生子牛 / IL1β … More
Except Principal Investigator
乳房炎 / 牛 / 獣医学 / 黄色ブドウ球菌 / ファージセラピー / ファージ / BLAD / 薬剤耐性菌 / ワクチン / 緑膿菌 / バクテリオファージ / 細菌感染症 / 繁殖 / 子宮内膜炎 / 白血球機能 / Bifidobacterium breve / 乳酸菌 / 乳腺感染制御 / 有用微生物 / 抗生物質 / 感染症 / ウシ乳房炎 / MRSA / 牛乳房炎 / エンドトキシン / 呼吸器疾患 / 大気汚染物質 / 大気科学 / 感染症対策 / 家畜衛生 / 環境衛生 / バイオエアロゾル / 大気化学 / エンドライシン / 耐性化 / トレードオフ / ファージ耐性化 / 臨床試験 / 大腸菌 / 畜産学 / 応用微生物学 / 臨床 / 細菌感染 / 子宮内細菌 / 細菌 / 子宮 / 乾乳期 / 乳腺上皮細胞 / 乳腺 / CATTLE DISEASE / SIGNAL TRANSDUCTION / GENETIC DISEASE / CD18-DEFICIENCY / BOVINE NEUTROPHILS / L-selectin / β2-integrin / superoxide / signaling / genetic disease / β_2-integrin / Signal transduction / CD18-deficiency / bovine neutrophils / Bifidobacterium breve / 乳牛 / クリアランス / 乳房炎制御 / 非薬物治療 / 自然免疫 / 乳体細胞 / portable test system / Limulus Amevocyte Lysate / エンドトキシン活性値 / 牛複合生呼吸器疾患’ / Cow SideTest / 予後判断 / 15員環マクロライド / 予防診断 / 牛呼吸器病症候群 / 甚急性乳房炎 / 予後判定 / Cow Side Test / ウシ / 角膜炎 / ウマ細菌性角膜炎 / 免疫機能 / 感染 / 細胞診 / マイコプラズマ / 表面マーカ / 感染防御応答 / 感染制御効果 / サイトカイン発現 / 乳房内注入 / 乳体細胞の誘導 / サイトカイン / 白血球機能修飾 / 医療・福祉 / 微生物 / アミノ酸 / 微量元素 / 肺胞洗浄液 / Mycoplasma / 肺炎起因菌 / 高張食塩液 / 気管支鏡 Less
  • Research Projects

    (21 results)
  • Research Products

    (186 results)
  • Co-Researchers

    (35 People)
  •  Immune evasion mechanisms and pathogenesis-related factors of mycoplasma in bovine tracheal epithelial cells.Principal Investigator

    • Principal Investigator
      樋口 豪紀
    • Project Period (FY)
      2023 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 42020:Veterinary medical science-related
    • Research Institution
      Rakuno Gakuen University
  •  Cell biological studies on the mechanism of advanced immune evasion of mycoplasma in bovine synovial tissue.Principal Investigator

    • Principal Investigator
      Higuchi Hidetoshi
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 42020:Veterinary medical science-related
    • Research Institution
      Rakuno Gakuen University
  •  Development and clinical application of next-generation phage therapy

    • Principal Investigator
      Iwano Hidetomo
    • Project Period (FY)
      2017 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Veterinary medical science
    • Research Institution
      Rakuno Gakuen University
  •  Development of a new therapeutic method using phage for endometritis in cows

    • Principal Investigator
      Ando Takaaki
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Veterinary medical science
    • Research Institution
      Kagoshima University
  •  A cell biological approach to immune escape mechanism of Mycoplasma in bovine mammary tissuePrincipal Investigator

    • Principal Investigator
      Higuchi Hidetoshi
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Veterinary medical science
    • Research Institution
      Rakuno Gakuen University
  •  乾乳期のウシ乳腺組織における再構築メカニズムの解明

    • Principal Investigator
      中島 恵一
    • Project Period (FY)
      2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Animal production science
    • Research Institution
      National Agriculture and Food Research Organization
  •  Impact assessment for air pollutants affecting infectivity of bioaerosols and disease prevention

    • Principal Investigator
      Noda Jun
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Environmental impact assessment
    • Research Institution
      Rakuno Gakuen University
  •  Study on Pathophysiology of cattle inflammatory diseases as an indicator of endotoxin activity value and establishment of rapid prognostic diagnosis

    • Principal Investigator
      SUZUKI KAZUYUKI
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Veterinary medical science
    • Research Institution
      Rakuno Gakuen University
  •  Intramammary infusion of food-grade lactic acid bacteria (Bifidobacterium breve) on cellular and immuno-modulatory functions in mammary glands and therapeutic trials on bovine mastitis in dairy cows.

    • Principal Investigator
      NAGAHATA Hajime
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Veterinary medical science
    • Research Institution
      Rakuno Gakuen University
  •  Research of phage therapy and phage vaccine for bacterial infectious diseases.

    • Principal Investigator
      IWANO Hidetomo
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Veterinary medical science
    • Research Institution
      Rakuno Gakuen University
  •  Etiology of endometritis and its relation with intrauterine infection of Mycoplasma spp

    • Principal Investigator
      OSAWA Takeshi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Clinical veterinary science
    • Research Institution
      University of Miyazaki
  •  Basic study for development of a novel method for bovine mastitisPrincipal Investigator

    • Principal Investigator
      HIGUCHI HIDETOSHI
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Applied veterinary science
    • Research Institution
      Rakuno Gakuen University
  •  Applied research of phage therapy for bovine mastitis

    • Principal Investigator
      IWANO Hidetomo
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Clinical veterinary science
    • Research Institution
      Rakuno Gakuen University
  •  Cellular and Immune Responses of Dairy Cows Induced by Intramammary Infusion of Lactic Acid Bacteria and Therapeutic Trials to Quarters of Cows with Mastitis.

    • Principal Investigator
      NAGAHATA Hajime
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied veterinary science
    • Research Institution
      Rakuno Gakuen University
  •  A cell biological study of immunological diversity in bovine mammary tissuePrincipal Investigator

    • Principal Investigator
      HIGUCHI Hidetoshi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied veterinary science
    • Research Institution
      Rakuno Gakuen University
  •  Study on pathophysiological and image diagnostic evaluations in calves with Bovine Respiratory Disease Complex.

    • Principal Investigator
      SUZUKI Kazuyuki
    • Project Period (FY)
      2009 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Clinical veterinary science
    • Research Institution
      Rakuno Gakuen University
  •  immune response in bovine mammary gland infectionPrincipal Investigator

    • Principal Investigator
      HIGUCHI Hidetoshi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied veterinary science
    • Research Institution
      Rakuno Gakuen University
  •  ウシ蹄組織の構成成分および物理性状に関する予防衛生学的研究Principal Investigator

    • Principal Investigator
      樋口 豪紀
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Applied veterinary science
    • Research Institution
      Rakuno Gakuen University
  •  ウシ蹄組織の角質形成およびその性状に関する予防衛生学的研究Principal Investigator

    • Principal Investigator
      樋口 豪紀
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Applied veterinary science
    • Research Institution
      Rakuno Gakuen University
  •  新生子牛における好中球機能の発現調節機構に関する研究Principal Investigator

    • Principal Investigator
      樋口 豪紀
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Applied veterinary science
    • Research Institution
      Rakuno Gakuen University
  •  Characterization of CD18-Deficient Neutrophil Functions and Some Modulations of Bovine Neutrophils from Cattle with Bovine Leukocyte Adhesion Deficiency

    • Principal Investigator
      NAGAHATA Hajime
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied veterinary science
    • Research Institution
      RAKUNO GAKUEN UNIVERSITY, FACULTY OF VETERINARY MEDICINE

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All Journal Article Presentation

  • [Journal Article] Invasion of Mycoplasma bovis into bovine synovial cells utilizing the clathrin-dependent endocytosis pathway2021

    • Author(s)
      Nishi Koji、Gondaira Satoshi、Fujiki Jumpei、Katagata Michiko、Sawada Chizuru、Eguchi Ayako、Iwasaki Tomohito、Iwano Hidetomo、Higuchi Hidetoshi
    • Journal Title

      Veterinary Microbiology

      Volume: 253 Pages: 108956-108956

    • DOI

      10.1016/j.vetmic.2020.108956

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K06425
  • [Journal Article] Transcriptome analysis of Mycoplasma bovis stimulated bovine peripheral blood mononuclear cells2021

    • Author(s)
      Gondaira Satoshi、Nishi Koji、Iwano Hidetomo、Fujiki Jumpei、Watanabe Reina、Eguchi Ayako、Hirano Yuki、Higuchi Hidetoshi、Nagahata Hajime
    • Journal Title

      Veterinary Immunology and Immunopathology

      Volume: 232 Pages: 110166-110166

    • DOI

      10.1016/j.vetimm.2020.110166

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K06425
  • [Journal Article] Effects of intra-articular inoculation with Mycoplasma bovis on immunological responses in calf joints2021

    • Author(s)
      Koji Nishi, Yuki Hirano, Ayano Sato, Ayako Eguchi, Kazuya Matsuda, Miyuki Toda, Takafumi Watanabe, Tomohito Iwasaki, Naoki Takahashi, Marina Hosotani, Reina Watanabe, Toshihide Kato, Hiromichi Ohtsuka, Satoshi Gondaira, *,Hidetoshi Higuchia,*
    • Journal Title

      Veterinary Immunology and Immunopathology

      Volume: 244 Pages: 248-248

    • DOI

      10.1016/j.vetimm.2021.110364

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K06425
  • [Journal Article] Inflammatory cytokine mRNA and protein levels in the synovial fluid of <i>Mycoplasma</i> arthritis calves2021

    • Author(s)
      Koji NISHI, Satoshi GONDAIRA, Mariko OKAMOTO, Kazuya MATSUDA, Ayano SATO, Toshihide KATO, Misawo SASAGAWA, Takahiro TANAK and Hidetoshi HIGUCHI*
    • Journal Title

      Journal of Veterinary Medical Science

      Volume: 83 Issue: 1 Pages: 31-35

    • DOI

      10.1292/jvms.20-0491

    • NAID

      130007967849

    • ISSN
      0916-7250, 1347-7439
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K06425
  • [Journal Article] A case-control study of herd- and cow-level risk factors associated with an outbreak of Mycoplasma mastitis in Nemuro, Japan.2020

    • Author(s)
      Fujimoto Y, Ito H, Higuchi H, Ohno H, Makita K
    • Journal Title

      Preventive Veterinary Medicine

      Volume: 177 Pages: 104946-104946

    • DOI

      10.1016/j.prevetmed.2020.104946

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18KK0184, KAKENHI-PROJECT-19K06425
  • [Journal Article] Immunosuppression in cows following intramammary infusion of Mycoplasma bovis2020

    • Author(s)
      Gondaira S, Nishi K, Tanaka T, Yamamoto T, Nebu T, Watanabe R, Konnai S, Hayashi T, Kiku Y, Okamoto M, Matsuda K, Koiwa M, Iwano H, Nagahata H, Higuchi H.
    • Journal Title

      Infect Immun.

      Volume: 88(3) Issue: 3

    • DOI

      10.1128/iai.00521-19

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19KK0172, KAKENHI-PROJECT-17H01506
  • [Journal Article] The Suppression of Th1 Response by Inducing TGF-β1 From Regulatory T Cells in Bovine Mycoplasmosis2020

    • Author(s)
      Sajiki Yamato、Konnai Satoru、Goto Shinya、Okagawa Tomohiro、Ohira Kosuke、Shimakura Honami、Maekawa Naoya、Gondaira Satoshi、Higuchi Hidetoshi、Tajima Motoshi、Hirano Yuki、Kohara Junko、Murata Shiro、Ohashi Kazuhiko
    • Journal Title

      Frontiers in Veterinary Science

      Volume: 7 Pages: 2564-2569

    • DOI

      10.3389/fvets.2020.609443

    • NAID

      120007193553

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K06425, KAKENHI-PROJECT-20K21357, KAKENHI-PROJECT-19KK0172, KAKENHI-PROJECT-18H02332, KAKENHI-PROJECT-19J21826, KAKENHI-PROJECT-19K15993
  • [Journal Article] Susceptibility of Pseudomonas aeruginosa veterinary isolates to Pbunavirus PB1‐like phages2020

    • Author(s)
      Fujiki Jumpei、Furusawa Takaaki、Munby Montgomery、Kawaguchi Chika、Matsuda Yumie、Shiokura Yusei、Nakamura Keisuke、Nakamura Tomohiro、Sasaki Michihito、Usui Masaru、Iwasaki Tomohito、Gondaira Satoshi、Higuchi Hidetoshi、Sawa Hirofumi、Tamura Yutaka、Iwano Hidetomo
    • Journal Title

      Microbiology and Immunology

      Volume: 64 Issue: 11 Pages: 778-782

    • DOI

      10.1111/1348-0421.12846

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K15985, KAKENHI-PROJECT-17H01506, KAKENHI-PROJECT-20J23348
  • [Journal Article] Mycoplasma bovis induces matrix metalloproteinase-3 expression in bovine synovial cells via up-regulation of interleukin-1β expression in mononuclear cells2020

    • Author(s)
      Nishi Koji、Gondaira Satoshi、Okamoto Mariko、Watanabe Reina、Hirano Yuki、Fujiki Jumpei、Iwano Hidetomo、Higuchi Hidetoshi
    • Journal Title

      Veterinary Immunology and Immunopathology

      Volume: 227 Pages: 110057-110057

    • DOI

      10.1016/j.vetimm.2020.110057

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K06425
  • [Journal Article] Upregulation of PD-L1 Expression by Prostaglandin E2 and the Enhancement of IFN-γ by Anti-PD-L1 Antibody Combined With a COX-2 Inhibitor in Mycoplasma bovis Infection2020

    • Author(s)
      Goto Shinya、Konnai Satoru、Hirano Yuki、Kohara Junko、Okagawa Tomohiro、Maekawa Naoya、Sajiki Yamato、Watari Kei、Minato Erina、Kobayashi Atsuhi、et al.
    • Journal Title

      Frontiers in Veterinary Science

      Volume: 7 Pages: 12-12

    • DOI

      10.3389/fvets.2020.00012

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K05963, KAKENHI-PROJECT-19KK0172, KAKENHI-PROJECT-18H02332, KAKENHI-PROJECT-18J13237, KAKENHI-PROJECT-19J21826, KAKENHI-PROJECT-19K06425, KAKENHI-PROJECT-20K21357, KAKENHI-PROJECT-19K15993
  • [Journal Article] Effect of Mycoplasma bovis on expression of inflammatory cytokines and matrix metalloproteinases mRNA in bovine synovial cells.2019

    • Author(s)
      Koji Nishi,Satoshi Gondaira,Mariko Okamoto,Takanori Nebu,Masateru Koiwa,Hiromichi Ohtsuka,Kiyokazu Murai,Kazuya Matsuda,Jumpei Fujiki,Hidetomo Iwano,Hajime Nagahata,Hidetoshi Higuchi
    • Journal Title

      Veterinary immunology and immunopathology

      Volume: 216 Pages: 109920-109920

    • DOI

      10.1016/j.vetimm.2019.109920

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H01506
  • [Journal Article] ファージセラピーの現状と動物医療への応用2019

    • Author(s)
      岩野英知、藤木純平、中村暢宏、権平智、樋口豪紀
    • Journal Title

      産業動物臨床医誌

      Volume: 10 Pages: 53-59

    • NAID

      130007719101

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H01506
  • [Journal Article] Prevalence and risk factors of Mycoplasma bovis infection in dairy farms in T northern Japan2019

    • Author(s)
      Kiyokazu Murai, Hidetoshi Higuchi.
    • Journal Title

      Res. Vet. Sci.

      Volume: 123 Pages: 29-31

    • Data Source
      KAKENHI-PROJECT-15K07749
  • [Journal Article] ファージセラピーの臨床応用と世界の動向 - パターソン症例から2018

    • Author(s)
      藤木純平、樋口豪紀、岩野英知
    • Journal Title

      ケミカルタイムス

      Volume: 4 Pages: 25-31

    • NAID

      120006798178

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H01506
  • [Journal Article] Characterization of the Lytic Capability of a LysK-Like Endolysin, Lys-phiSA012, Derived from a Polyvalent Staphylococcus aureus Bacteriophage.2018

    • Author(s)
      Fujiki J, Nakamura T, Furusawa T, Ohno H, Takahashi H, Kitana J, Usui M, Higuchi H, Tanji Y, Tamura Y, Iwano H.
    • Journal Title

      Pharmaceuticals (Basel).

      Volume: 11 Issue: 1 Pages: 25-25

    • DOI

      10.3390/ph11010025

    • NAID

      120006798141

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H01506
  • [Journal Article] Anesthetic and cardiorespiratory effects of single-bolus intravenous alfaxalone with or without intramuscular xylazine-premedication in calves2018

    • Author(s)
      El-Hawari S, Sakata H, Oyama N, Tamura J, Higuchi C, Endo Y, Miyoshi K, Sano T, Suzuki K, Yamashita K.
    • Journal Title

      Journal of Veterinary Medical Science

      Volume: 80 Issue: 2 Pages: 361-367

    • DOI

      10.1292/jvms.17-0512

    • NAID

      130006410782

    • ISSN
      0916-7250, 1347-7439
    • Language
      English
    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26450431
  • [Journal Article] Innate immune response of bovine mammary epithelial cells to Mycoplasma bovis.2018

    • Author(s)
      Gondaira, S., Higuchi, H., Iwano H., Nishi, K., Nebu, T., Nakajima, K, and Nagahata, H.
    • Journal Title

      J Vet Sci

      Volume: 19 Pages: 79-87

    • NAID

      120006798144

    • Data Source
      KAKENHI-PROJECT-15K07749
  • [Journal Article] Bacteriophage ΦSA012 Has a Broad Host Range against Staphylococcus aureus and Effective Lytic Capacity in a Mouse Mastitis Model.2018

    • Author(s)
      Iwano H, Inoue Y, Takasago T, Kobayashi H, Furusawa T, Taniguchi K, Fujiki J, Yokota H, Usui M, Tanji Y, Hagiwara K, Higuchi H, Tamura Y.
    • Journal Title

      Biology (Basel).

      Volume: 7 Issue: 1 Pages: 8-8

    • DOI

      10.3390/biology7010008

    • NAID

      120006648419

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H01506
  • [Journal Article] Mycoplasma bovis escapes bovine neutrophil extracellular traps.2017

    • Author(s)
      Gondaira, S., Higuchi, H., Nishi, K., Iwano, H. and Nagahata, H.
    • Journal Title

      Veterinary Microbioligy

      Volume: 199 Pages: 68-73

    • DOI

      10.1016/j.vetmic.2016.12.022

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K07749
  • [Journal Article] Mycoplasma bovis escapes bovine neutrophil extracellular traps.2017

    • Author(s)
      Gondaira, S., Higuchi, H., Nishi, K., Iwano, H. and Nagahata, H.
    • Journal Title

      Veterinary Microbiology

      Volume: 199 Issue: 1 Pages: 68-73

    • DOI

      10.4142/jvs.2018.19.1.79

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K07749, KAKENHI-PROJECT-17H01506
  • [Journal Article] 1.Complete Genome Sequencing of the Broad-Host-Range Pseudomonas aeruginosa Bacteriophages ΦR18 and ΦS12-1.2016

    • Author(s)
      Takaaki Furusawa, Hidetomo Iwano, Hidetoshi Higuchi, Masaru Usui, Fumito Maruyama, Ichiro Nakagawa, Hiroshi Yokota, Yutaka Tamura.
    • Journal Title

      Genome Announcements

      Volume: 4-3 Issue: 3 Pages: 1-2

    • DOI

      10.1128/genomea.00041-16

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25292182, KAKENHI-PROJECT-16H05188, KAKENHI-PROJECT-15K15130
  • [Journal Article] 牛乳房炎へのBifidobacterium breve注入に伴う乳腺の反応性とサイトカイン産生2016

    • Author(s)
      國分千尋、浅井友紀子、澤田知佳、丸山久美子、権平 智、樋口豪紀、永幡 肇
    • Journal Title

      家畜衛生学雑誌

      Volume: 42 Pages: 140-141

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26450432
  • [Journal Article] Bacteriophage can lyse antibiotic-resistant Pseudomonas aeruginosa isolated from canine diseases.2016

    • Author(s)
      Furusawa, T., Iwano, H., Higuchi, H., Yokota, H., Usui, M. and Tamura, Y.
    • Journal Title

      J Vet Med Sci.

      Volume: in press

    • NAID

      130005159671

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25292182
  • [Journal Article] Cytokine mRNA profiling and the proliferative response of bovine peripheral blood mononuclear cells to Mycoplasma bovis.2015

    • Author(s)
      Gondaira S, Higuchi H, Iwano H, Nakajima K, Kawai K, Hashiguchi S, Konnai S, Nagahata H.
    • Journal Title

      Vet Immunol Immunopathol.

      Volume: 165 Issue: 1-2 Pages: 45-53

    • DOI

      10.1016/j.vetimm.2015.03.002

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25292182, KAKENHI-PROJECT-26450432, KAKENHI-PROJECT-25257415
  • [Journal Article] Cytokine mRNA profiling and the proliferative response of bovine peripheral blood mononuclear cells to Mycoplasma bovis.2015

    • Author(s)
      Gondaira, S., Higuchi, H., Iwano, H., Nakajima, K., Kawai, K., Hashiguchi, S., Konnai, S., and Nagahata, H.
    • Journal Title

      Vet Immunol Immunopathol.

      Volume: 165 Pages: 45-43

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25292182
  • [Journal Article] paperCytokine mRNA profiling and the proliferative response ofbovine peripheral blood mononuclear cells to Mycoplasmabovis2015

    • Author(s)
      Satoshi Gondaira, Hidetoshi Higuchi, Hidetomo Iwano, Keiichi Nakajima,Kazuhiro Kawai, Shuhei Hashiguchi, Satoru Konnai, Hajime Nagahata
    • Journal Title

      Vet. immune. Immunopathol.

      Volume: in press

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24658260
  • [Journal Article] Intramammary infusion of lactic acid bacteria and therapeutic effects on mastitis in dairy cows.2015

    • Author(s)
      Nagahata, H., Horiguchi, M., Tamiya, A., Gondaira, S., Higuchi, H. & kawai, K.
    • Journal Title

      International Society of Animal Hygiene

      Volume: 1 Pages: 132-133

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26450432
  • [Journal Article] Molecular Epidemiology of cases of Mycoplasma californicum infection in Japan.2014

    • Author(s)
      Hata, E., Suzuki K, Hanyu, H., Itoh, M., Higuchi, H., Kobayashi, H.
    • Journal Title

      Appl. Environ Microbiol.

      Volume: 80 Issue: 24 Pages: 7717-7724

    • DOI

      10.1128/aem.02488-14

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24658260
  • [Journal Article] 牛乳房炎分房へのBifidobacterium breve注入に伴う乳腺の反応性とサイトカイン遺伝子発現2014

    • Author(s)
      堀口 萌、権平 智、樋口豪紀、永幡 肇
    • Journal Title

      家畜衛生学雑誌

      Volume: 40 Pages: 118-119

    • Data Source
      KAKENHI-PROJECT-26450432
  • [Journal Article] 3.Antimicrobial Susceptibilities of Mycoplasma Isolated from Bovine Mastitis in Japan.2014

    • Author(s)
      Kawai, K., Higuchi, H., Iwano, H., Iwakuma, A., Onda, K., Sato, R., Hayashi, T., Nagahata, H. and Oshida
    • Journal Title

      Anim. Sci. J.

      Volume: 86 Pages: 96-99

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24658260
  • [Journal Article] Antimicrobial susceptibilities of Mycoplasma isolated from bovine mastitis in Japan.2014

    • Author(s)
      Kawai K, Higuchi H, Iwano H, Iwakuma A, Onda K, Sato R, Hayashi T, Nagahata H, Oshida T.
    • Journal Title

      Anim Sci J.

      Volume: 85 Issue: 1 Pages: 96-99

    • DOI

      10.1111/asj.12144

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25292182, KAKENHI-PROJECT-25450457
  • [Journal Article] Mycoplasma species isolated from intramammary infection of Japanese dairy cows.2013

    • Author(s)
      Higuchi H, Gondaira S, Iwano H, Hirose K, Nakajima K, Kawai K, Hagiwara K, Tamura Y, Nagahata H
    • Journal Title

      Veterinary Record

      Volume: In press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24658260
  • [Journal Article] Relationship between concentration of lingual antimicrobial peptide and somatic cell count in milk of dairy cows.2013

    • Author(s)
      Kawai K, Akamatsu H, Obayashi T, Nagahata H, Higuchi H, Iwano H, Oshida T, Yoshimura Y, Isobe N
    • Journal Title

      Veterinary Immunology and Immunopathology

      Volume: 153(3-4) Issue: 3-4 Pages: 298-301

    • DOI

      10.1016/j.vetimm.2013.03.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24580410, KAKENHI-PROJECT-25292182
  • [Journal Article] Effects of vitamin E supplementation on cellular α-tocopherol concentrations of neutrophils in Holstein calves.2013

    • Author(s)
      Higuchi H, Ito E, Iwano H, Oikawa S, Nagahata H.
    • Journal Title

      Canadian Journal of Veterinary Research

      Volume: 77 Pages: 120-125

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24658260
  • [Journal Article] Effects of vitamin E supplementation on cellular α-tocopherol concentrations of neutrophils in Holstein calves.2013

    • Author(s)
      Higuchi H, Ito E, Iwano H, Oikawa S, Nagahata H.
    • Journal Title

      Can J Vet Res.

      Volume: 77 Pages: 120-125

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25292182
  • [Journal Article] Mycoplasma species isolated from intramammary infection of Japanese dairy cows.2013

    • Author(s)
      Higuchi, H., Gondaira, S., Iwano, H., Hirose, K., Nakajima, K., Kawai, K., Hagiwara, K., Tamura, Y., Nagahata, H.
    • Journal Title

      Veterinary Record

      Volume: 172 Pages: 172-172

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24658260
  • [Journal Article] Mycoplasma species isolated from intramammary infection of Japanese dairy cows.2013

    • Author(s)
      Higuchi H, Gondaira S, Iwano H, Hirose K, Nakajima K, Kawai K, Hagiwara K, Tamura Y, Nagahata H.
    • Journal Title

      Vet Rec.

      Volume: 172 Issue: 21 Pages: 557-557

    • DOI

      10.1136/vr.101228

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25292182
  • [Journal Article] Analysis of Trace and Major Elements in Bronchoalveolar Lavage Fluid of Mycoplasma Bronchopneumonia in Calves2012

    • Author(s)
      Suzuki K, Higuchi H, Iwano H, Lakritz J, Sera K, Koiwa M, Taguchi K
    • Journal Title

      Biological Trace Element Research

      Volume: 145 Issue: 2 Pages: 166-171

    • DOI

      10.1007/s12011-011-9180-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21580393
  • [Journal Article] Analysis of trace and major elements in bronchoalveolar lavage fluid of Mycoplasma bronchopneumonia in calves2012

    • Author(s)
      Suzuki K, Higuchi H, Iwano H, Lakritz J, Sera K, Koiwa M, Taguchi K
    • Journal Title

      Biol. Trace. Elem. Res.Feb

      Volume: 145(2):166-71

    • Data Source
      KAKENHI-PROJECT-22380174
  • [Journal Article] Effectiveness of slightly acidic electrolyzed water for improvement of hygienic conditions of teat liners of automatic milking system2012

    • Author(s)
      Nagahata, H., Yuge, K., Moriyama, A., Takahashi, A., Iwano, H., Higuchi, H., Mitamura, T. & Matsuyama, H
    • Journal Title

      Milchwissenschaft

      Volume: 67(2): 123-126

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22580354
  • [Journal Article] Analysis of cellular and immune responses of dairy cows induced by intramammary infusion of lactic acid bacteria and therapeutic trials to quarters of cows with mastitis2012

    • Author(s)
      Nagahata, H., Moriyama, A., Koshi, A.,Mukai, T., Natsume, Y., Higuchi, T., Koike, N. & Ando, T
    • Journal Title

      World Buiatrics Congress

      Pages: 32-33

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22580354
  • [Journal Article] Analysis of Trace and Major Elements in Bronchoalveolar Lavage Fluid of Mycoplasma Bronchopneumonia in Calves2012

    • Author(s)
      Suzuki K, Higuchi H, Iwano H, Lakritz J, Sera K, Koiwa M, Taguchi K
    • Journal Title

      Biol Trace Elem Res

      Volume: 145(2): 166-171

    • Data Source
      KAKENHI-PROJECT-21580393
  • [Journal Article] Effects of vitamin E supplementation on cellular a-tocopherol concentrations of neutrophils in Holstein calves2012

    • Author(s)
      Higuchi, H., Ito, E., Iwano, H., Oikawa, S. and Nagahata, H
    • Journal Title

      Can. J. Vet. Res

    • Data Source
      KAKENHI-PROJECT-22380174
  • [Journal Article] Mycoplasma infection in the uterus of early postpartum dairy cows and its relation to dystocia and endometritis.2012

    • Author(s)
      Ghanem, M. E., Higuchi, H., Tezuka, E., Ito, H., Devkota, B., Izaike, Y. and Osawa, T
    • Journal Title

      Theriogenology

      Volume: 79 Pages: 180-185

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24658260
  • [Journal Article] Analysis of trace and major elements in bronchoalveolar lavage fluid of Mycoplasma bronchopneumonia in calves.2012

    • Author(s)
      Suzuki K, Higuchi H, Iwano H, Lakritz J, Sera K, Koiwa M, Taguchi K.
    • Journal Title

      Biol. Trace. Elem. Res.

      Volume: 145 Pages: 166-171

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22380174
  • [Journal Article] Effectiveness of slightly acidic electrolyzed water for improvement of hygienic conditions of teat liners of automatic milking system.2012

    • Author(s)
      Nagahata, H., Yuge, K., Moriyama, A., Takahashi, A., Iwano, H., Higuchi, H., Mitamura, T. and Matsuyama, H.
    • Journal Title

      Milchwissenschaft,

      Volume: 67 Pages: 123-126

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22380174
  • [Journal Article] Prevalence of Mycoplasma species in bulk tank milk in Japan2011

    • Author(s)
      Higuchi, H., Iwano, H., Gondaira, S., Kawai, K., Nagahata, H.
    • Journal Title

      Vet.Rec.

      Volume: 169 Pages: 442-443

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22380174
  • [Journal Article] Analysis of trace and major elements in bronchoalveolar lavage fluid of mycoplasma bronchopneumonia in calves2011

    • Author(s)
      Suzuki, K., Higuchi, H., Iwano, H., Lakritz, J., Sera, K., Koiwa, M., Taguchi, K.
    • Journal Title

      Biol.Trace.Elem.Res.

      Volume: 145 Pages: 166-171

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22380174
  • [Journal Article] Altered leukocyte responsiveness in dairy cows with naturally occurring chronic Staphylococcus aureus mastitis2011

    • Author(s)
      Nagahata, H., Kawai, H., Higuchi, H., Kawai, K., Chang, C.J.
    • Journal Title

      Journal of Veterinary Medical Science

      Volume: 73(7) Pages: 885-894

    • NAID

      130000676901

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22580354
  • [Journal Article] Altered leukocyte responsiveness in dairy cows with naturally occurring chronic Staphylococcus aureus mastitis2011

    • Author(s)
      Nagahata, H., Kawai, H., Higuchi, H., Kawai, K., et al
    • Journal Title

      Journal of Veterinary Medical Science

      Volume: 73

    • NAID

      130000676901

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21580380
  • [Journal Article] 黄色ブドウ球菌に対する特異的なファージを用いたウシ乳房炎治療応用への可能性2011

    • Author(s)
      岩野英知、樋口豪紀、井上博紀、萩原克郎、横田博、永幡肇、丹治保典、田村豊
    • Journal Title

      日本乳房炎研究会Proceedings

      Volume: 第15回 Pages: 41-44

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22380174
  • [Journal Article] Analysis of trace and major elements in bronchoalveolar lavage fluid of mycoplasma bronchopneumonia in calves2011

    • Author(s)
      Suzuki, K., Higuchi, H., Iwano, H., Lakritz, J., Sera, K., Koiwa, M., Taguchi, K
    • Journal Title

      Biol. Trace. Elem. Res

      Volume: 145:166-171

    • Data Source
      KAKENHI-PROJECT-22380174
  • [Journal Article] Prevalence of Mycoplasma species in bulk tank milk in Japan2011

    • Author(s)
      Higuchi, H., Iwano, H., Gondaira, S., Kawai, K., Nagahata, H
    • Journal Title

      Veterinary Record

      Volume: 169 Pages: 442-442

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21580380
  • [Journal Article] A simplified PCR assay for fast and easy mycoplasma mastitis screening in dairy cattle2011

    • Author(s)
      Higuchi, H., Iwano, H., Kawai, K., Ohta, T., Obayashi, T., Hirose, K., Itoh, N., Yokota, T., Tamura, Y. and Nagahata, H
    • Journal Title

      J. Vet. Sci

      Volume: 12: 191-193

    • NAID

      120005761687

    • Data Source
      KAKENHI-PROJECT-22380174
  • [Journal Article] Analysis of Trace and Major Elements in Bronchoalveolar Lavage Fluid of Mycoplasma Bronchopneumonia in Calves2011

    • Author(s)
      Suzuki, K., Higuchi, H., Iwano, H., Lakritz, J., Sera, K., Koiwa, M., Taguchi, K.
    • Journal Title

      Biol. Trace. Elem. Res

      Volume: 145 Pages: 166-171

    • Data Source
      KAKENHI-PROJECT-21580380
  • [Journal Article] A simplified PCR assay for fast and easy mycoplasma mastitis screening in dairy cattle2011

    • Author(s)
      Higuchi, H., Iwano, H., Kawai, K., Ohta, T., Obayashi, T., Hirose, K., Itoh, N., Yokota, T., Tamura, Y., Nagahata, H.
    • Journal Title

      J.Vet.Sci.

      Volume: 12 Pages: 191-193

    • NAID

      120005761687

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22380174
  • [Journal Article] A simplified PCR assay for fast and easy screening of Mycoplasma mastitis of dairy cattle2011

    • Author(s)
      Higuchi, H., Iwano, H., Kawai, K., Ohta, T., Obayashi, T., Hirose, K, Ito, N., Yokota, H., Tamura, Y., Nagahata, H.
    • Journal Title

      J. Vet. Sci

      Volume: 12 Pages: 191-193

    • Data Source
      KAKENHI-PROJECT-21580380
  • [Journal Article] A simplified PCR assay for fast and easy mycoplasma mastitis screening in dairy cattle2011

    • Author(s)
      Higuchi, H., Iwano, H., Kawai, K., Ohta, T., Obayashi, et al
    • Journal Title

      Journal of Veterinary Science

      Volume: 12 Pages: 191-193

    • NAID

      120005761687

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21580380
  • [Journal Article] Altered leukocyte responsiveness in dairy cows with naturally occurring chronic Staphylococcus aureus mastitis2011

    • Author(s)
      Nagahata, H., Kawai, H., Higuchi, H., Kawai, K., Yayou, K. & Chang, C. J
    • Journal Title

      J. Vet. Med. Sci

      Volume: 73(7): 885-894

    • NAID

      130000676901

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22580354
  • [Journal Article] Prevalence of Mycoplasma species in bulk tank milk in Japan2011

    • Author(s)
      Higuchi, H., Iwano, H., Gondaira, S., Kawai, K., Nagahata, H
    • Journal Title

      Vet. Rec

      Volume: 169:442

    • Data Source
      KAKENHI-PROJECT-22380174
  • [Journal Article] Prevalence of Mycoplasma species in bulk tank milk in Japan2011

    • Author(s)
      Higuchi, H., Iwano, H., Kawai, K., Gondaira, T., Nagahata, H.
    • Journal Title

      Vet. Rec

      Volume: 169 Pages: 442-442

    • Data Source
      KAKENHI-PROJECT-21580380
  • [Journal Article] Effects of Mycotoxin on Chemiluminescent Response and Cytokine mRNA Expression on Bovine Neutrophils2010

    • Author(s)
      Wada, K., Nabae, A., Higuchi, H., Nagahata, M.
    • Journal Title

      J. Vet. Med. Sci

      Volume: 72 Pages: 1507-1511

    • NAID

      130000307669

    • Data Source
      KAKENHI-PROJECT-21580380
  • [Journal Article] A retrospective survey of the prevalence of complex vertebral malformation carriers in 9 Holstein dairy herds in Hokkaido, Japan2010

    • Author(s)
      Nagahata, H., Nishiyama, T., Kanae, Y., Higuchi, H., Kawai, K., Endoh, D., Hayashi, M., Kurosawa, T.
    • Journal Title

      J. Vet. Med. Sci

      Volume: 71 Pages: 793-795

    • NAID

      130000134405

    • Data Source
      KAKENHI-PROJECT-21580380
  • [Journal Article] Effects of ammonia and hydrogen sulfide on physical and biochemical properties of the claw horn of Holstein cows.2009

    • Author(s)
      Higuchi H, Kurumado H, Mori M, Degawa A, Fujisawa H, Kuwano A, Nagahata H.
    • Journal Title

      Can.J.Vet.Res. 73

      Pages: 15-20

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21580380
  • [Journal Article] Comparison of serum lipid compositions, lipid peroxide,α-tocopherol and lipoproteins in captive marine mammals(bottlenose dolphins, spotted seals and West Indian manatees) and terrestrial mammals2009

    • Author(s)
      Kasamatsu, M., Kawauchi, R., Tsunokawa, M., Ueda, K., Uchida, E., Oikawa, S., Higuchi, H., Kawajiri, T., Uchida, S. and Nagahata, H.
    • Journal Title

      Res. Vet. Sci

      Volume: 86 Pages: 216-222

    • Data Source
      KAKENHI-PROJECT-21580380
  • [Journal Article] Characterization of bacterial population of raw milk from bovine mastitis by culture-dependent PCR DGGE method.2009

    • Author(s)
      Kaung Y, Tani K, Synnott A, Ohshina K, Higuchi H, Ngahata H, Tanji Y.
    • Journal Title

      Biochem Engineer.J. 45

      Pages: 76-81

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21580380
  • [Journal Article] Characterization of bacterial population of raw milk from bovine mastitis by culture-independent PCR-DGGE method2009

    • Author(s)
      Kuang, Y., Tani, K., Synnott, A. J., Ohshima, K., Higuchi, H., Nagahata, H. and Tanji, Y.
    • Journal Title

      Biochemical Engineering Journal

      Volume: 45 Pages: 76-81

    • NAID

      120006582021

    • Data Source
      KAKENHI-PROJECT-21580380
  • [Journal Article] Effects of ammonia and hydrogen sulfide on physical and biochemical properties of the claw horn of Holstein cows2009

    • Author(s)
      Higuchi, H., Kurumado, H., Mori, M., Degawa, A., Fujisawa, H., Kuwano, A. and Nagahata, H.
    • Journal Title

      Can. J. Vet. Res

      Volume: 73 Pages: 15-20

    • Data Source
      KAKENHI-PROJECT-21580380
  • [Journal Article] Characterization of bacterial population of raw milk from bovine mastitis by culture-independent PCR-DGGE method2008

    • Author(s)
      Ying Kuang, Kaori Tani, Aidan Synnott, Kazuhito Ohshima, Hidetoshi Higuchi, Hajime Nagahata^b, Yasunori Tanji^<a*>
    • Journal Title

      Biochem. Eng. J. (In press)(受理済み)

    • NAID

      120006582021

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19580362
  • [Journal Article] Characterization of bacterial population of raw milk from bovine mastitis by culture-independent PCR-DGGE method2008

    • Author(s)
      Ying Kuang, Kaori Tani, Aidan Synnott, Kazuhito Ohshima, Hidetoshi Higuchi, Hajime Nagahata, Yasunori Tanji
    • Journal Title

      Biochem. Eng. J in press

    • NAID

      120006582021

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19580362
  • [Journal Article] Controlling highly prevalent Staphylococcus aureus mastitis from the dairy herd2007

    • Author(s)
      Nagahata, H., Ito, H., Maruta, H., Nishikawa, Y., Susukino, H., Matsuki, S., Higuchi, H., Okuhira, T. & Anri, A.
    • Journal Title

      J.Vet.Med.Sci. 69

      Pages: 893-898

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19580362
  • [Journal Article] Complement receptor type 3 (CR3)- and Fc receptor (FcR)-mediated matrixmetaroproteinase 9 (MMP-9) secretion and their intracellular signaling of bovine neutrophils2007

    • Author(s)
      Higuchi, H., Ishizaka, M. and Nagahata, H
    • Journal Title

      Vet. Res. Commun 31

      Pages: 985-991

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19580362
  • [Journal Article] Antibacterial activity of bovine lactoferrin hydrolusate against mastitis pathogen its effect on superoxide production of bovine neutrophils2007

    • Author(s)
      Kawai, K., Shimazaki, K., Higuchi, H. and Nagahata, H
    • Journal Title

      Zoonoses and public Health 54

      Pages: 164-167

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19580362
  • [Journal Article] Controlling highly prevalent Staphylococcus aureus mastitis from the dairy herd2007

    • Author(s)
      Nagahata, H., Ito, H., Maruta, H., Nishikawa, Y., Susukino, H., Matsuki, S., Higuchi, H., Okuhira, T. & Anri, A
    • Journal Title

      J. Vet. Med. Sci 69

      Pages: 893-898

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19580362
  • [Journal Article] Antibacterial activity of bovine lactoferrin hydrolusate against mastitis athogen its effect on superoxide production of bovine neutronhils2007

    • Author(s)
      Kawai, K., Shimazaki, K., Higuchi, H., and Nagahata, H.
    • Journal Title

      Zoonoses and public Health 54

      Pages: 160-164

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19580362
  • [Journal Article] Complement receptor type 3(CR3)-and Fc receptor(FcR)-mediated matrlxmetaroproteinase 9(MMP-9)secretion and their intracellular signaling of bovine neutrophils2007

    • Author(s)
      Higuchi, H., Ishiizaka, M. and Nagahata, H.
    • Journal Title

      Vet.Res.Commun. 31

      Pages: 985-991

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19580362
  • [Journal Article] Effects of biotin supplementation on serum biotin levels and physical properties of samples of solar horn of Holstein cows2004

    • Author(s)
      Higuchi, H., et al.
    • Journal Title

      Canadian Journal of Veterinary Research 68

      Pages: 93-97

    • Data Source
      KAKENHI-PROJECT-15780198
  • [Journal Article] Effects of Mycotoxin on Chemiluminescent Response and Cytokine mRNA Expression on Bovine Neutrophils2000

    • Author(s)
      Wada, K., Nabae, A., Higuchi, H., Nagahata, M.
    • Journal Title

      Journal of Veterinary Medical Association

      Volume: 72 Pages: 1507-1511

    • NAID

      130000307669

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21580380
  • [Journal Article] simplified PCR assay for fast and easy screening of Mycoplasma mastitis of dairy cattle

    • Author(s)
      Higuchi, H., Iwano, H., Kawai, K., Ohta, T., Obayashi, T., Hirose, K, Ito, N., Yokota, H., Tamura, Y., Nagahata, H
    • Journal Title

      Journal of Veterinary Science

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21580380
  • [Presentation] Mycoplasma (Mycoplasmopsis) bovis infections in veterinary medicine.2023

    • Author(s)
      Gondaira, S., Nishi, K., Imaizumi, N. and Higuchi, H.
    • Organizer
      24th Biennial Congress of the International Organization for Mycoplasmology (IOM)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K05574
  • [Presentation] Mycoplasma bovisにおけるバイオフィルム形成メカニズムの解明2022

    • Author(s)
      濵村時羽, 権平智, 樋口豪紀
    • Organizer
      第12回家畜感染症学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K06425
  • [Presentation] PNAビーズを利用したMycoplasma bovisの新規検査技術の開発とその応用2022

    • Author(s)
      猪俣可那子, 房田京子, 権平智, 樋口豪紀
    • Organizer
      第49回日本マイコプラズマ学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K06425
  • [Presentation] PNAビーズによるマイコプラズマ乳房炎の新規検査技術の開発とその応用2022

    • Author(s)
      猪俣可那子, 房田京子, 権平智, 樋口豪紀
    • Organizer
      本家畜衛生学会第95回大会
    • Data Source
      KAKENHI-PROJECT-19K06425
  • [Presentation] 乳汁の常在細菌叢がウシ乳房炎に及ぼす影響2022

    • Author(s)
      権平智, 野田和希, 江口亜矢子, 今泉法子, 樋口豪紀
    • Organizer
      日本家畜衛生学会第95回大会
    • Data Source
      KAKENHI-PROJECT-19K06425
  • [Presentation] マイコプラズマボビスのバイオフィルム産生能が病原性に及ぼす影響2022

    • Author(s)
      権平智, 西航司, 今泉法子, 渡辺麗奈, 濵村時羽, 町野文菜, 長澤裕哉, 神田卓弥, 上村涼子, 樋口豪紀
    • Organizer
      第49回日本マイコプラズマ学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K06425
  • [Presentation] Mycoplasma bovisの遺伝子がバイオフィルム産生能と病原性に及ぼす影響2022

    • Author(s)
      権平智, 西航司, 今泉法子, 渡辺麗奈, 濵村時羽, 町野文菜, 長澤裕哉, 神田卓弥, 上村涼子, 樋口豪紀
    • Organizer
      日本家畜衛生学会第95回大会
    • Data Source
      KAKENHI-PROJECT-19K06425
  • [Presentation] 牛マイコプラズマ感染症発生牛群における血清抗体価の経時的変化2022

    • Author(s)
      湯本翔貴, 権平智, 中村光, 高橋拓己, 西航司, 藤木純平, 岩野英知, 樋口豪紀
    • Organizer
      日本家畜衛生学会第95回大会
    • Data Source
      KAKENHI-PROJECT-19K06425
  • [Presentation] 遊離アミノ酸がウシ乳腺の免疫学的応答性に及ぼす影響2022

    • Author(s)
      野田和希, 権平智, 江口亜矢子, 福森理加, 杉浦智親, 佐藤綾乃, 及川伸, 樋口豪紀
    • Organizer
      第27回日本乳房炎研究会学術集会
    • Data Source
      KAKENHI-PROJECT-19K06425
  • [Presentation] Fitness costによって誘導されるP. aeruginosa変異株のファージ感受性トレードオフ2020

    • Author(s)
      藤木純平, マンビモンゴメリ, 中村暢宏, 権平智, 佐々木道仁, 臼井優, 樋口豪紀, 澤洋文, 田村豊, 岩野, 英知
    • Organizer
      第93回日本細菌学会総会
    • Data Source
      KAKENHI-PROJECT-17H01506
  • [Presentation] Staphylococcus aureus に対する効果的なファージセラピーの応用2020

    • Author(s)
      北名 純也, 中村 暢宏, モンゴメリ マンビ, 藤木 純平, 樋口 豪紀, 臼井 優, 田村 豊, 岩野 英知
    • Organizer
      第93回日本細菌学会総会
    • Data Source
      KAKENHI-PROJECT-17H01506
  • [Presentation] ウシ関節組織におけるMycoplasma bovisの細胞侵入機構とその制御2020

    • Author(s)
      西航司、権平 智、岩崎智仁、渡部敬文、藤木純平、岩野英知、樋口豪紀
    • Organizer
      日本細菌学会
    • Data Source
      KAKENHI-PROJECT-19K06425
  • [Presentation] P. aeruginosaにおけるファージ耐性はFitness costとしてファージ感受性をシフトする2019

    • Author(s)
      藤木純平, 古澤貴章, マンビ・モンゴメリ, 川口千佳, 松田由美恵, 佐々木道仁, 臼井優, 樋口豪紀, 澤洋文, 田村豊, 岩野英知
    • Organizer
      第42回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-17H01506
  • [Presentation] P. aeruginosaが獲得した特異的ファージ耐性が示すファージ感受性の進化学的トレードオフ2019

    • Author(s)
      藤木純平, 古澤貴章, マンビ・モンゴメリ, 川口千佳, 松田由美恵, 佐々木道仁, 臼井優, 樋口豪紀, 澤洋文, 田村豊, 岩野英知
    • Organizer
      第13回細菌学若手コロッセウム
    • Data Source
      KAKENHI-PROJECT-17H01506
  • [Presentation] Staphylococcus aureusに対するバクテリオファージライブラリー構築に向けたファージ選抜法の検討2019

    • Author(s)
      北名純也, 高橋宏充, 中村暢宏, マンビ・モンゴメリ, 藤木純平, 樋口豪紀, 臼井優, 田村豊, 岩野英知
    • Organizer
      第42回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-17H01506
  • [Presentation] 子牛マイコプラズマ性肺炎に対するワクチン開発2019

    • Author(s)
      ○渡来 仁、塔 娜、樋口豪紀、小岩政照
    • Organizer
      日本獣医師会獣医学術学会
    • Data Source
      KAKENHI-PROJECT-15K07749
  • [Presentation] ファージ耐性化のFitness costはP. aeruginosaのファージ感受性にトレードオフを誘導する2019

    • Author(s)
      藤木純平, 古澤貴章, マンビ・モンゴメリ, 中村暢宏, 権平智, 佐々木道人, 臼井優, 樋口豪紀, 澤洋文, 田村豊, 岩野英知
    • Organizer
      第85回日本細菌学会北海道支部会学術総会
    • Data Source
      KAKENHI-PROJECT-17H01506
  • [Presentation] Staphylococcus aureuに対するファージライブラリー構築に向けたファージ選抜法の検討2019

    • Author(s)
      北名純也, 高橋宏充, 藤木純平, 中村暢宏, 臼井優, 樋口豪紀, 猪俣夢, 岩野英知
    • Organizer
      第92回日本細菌学会総会
    • Data Source
      KAKENHI-PROJECT-17H01506
  • [Presentation] Trade-off effects on phage sensitivity induced by phage resistance has a potential for strategic phage cocktails construction in phage therapy2019

    • Author(s)
      Fujiki J, Furusawa T, Montgomery Munby, Nakamura T, Usui M, Iwasaki T, Gondaira S, Higuchi H, Tamura Y, Iwano H
    • Organizer
      Phage Futures Europe
    • Data Source
      KAKENHI-PROJECT-17H01506
  • [Presentation] ファージ感受性トレードオフを応用した戦略的ファージカクテルの構築2019

    • Author(s)
      藤木純平, 古澤貴章, マンビ・モンゴメリ, 川口千佳, 松田由美恵, 権平智, 臼井優, 樋口豪紀, 田村豊, 岩野英知
    • Organizer
      第6回乳房炎サマーキャンプ
    • Data Source
      KAKENHI-PROJECT-17H01506
  • [Presentation] Staphylococcus aureusに対するバクテリオファージライブラリー構築に向けた溶菌活性評価法の検討2019

    • Author(s)
      北名純也, 高橋宏充, マンビ・モンゴメリ, 中村暢宏, 藤木純平, 樋口豪紀, 臼井優, 田村豊, 岩野英知
    • Organizer
      第85回日本細菌学会北海道支部会学術総会
    • Data Source
      KAKENHI-PROJECT-17H01506
  • [Presentation] 表皮疾患由来Pseudomonas aeruginosaに対する広域スペクトル溶菌性ファージの探索2019

    • Author(s)
      藤木純平, 古澤貴章, マンビ・モンゴメリ, 川口千佳, 松田由美恵, 権平智, 臼井優, 樋口豪紀, 岩野英知
    • Organizer
      第92回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-17H01506
  • [Presentation] ウシ乳房炎由来Staphylococcus aureusに対する効果的なバクテリオファージの応用2019

    • Author(s)
      北名純也, 中村暢宏, 藤木純平, 権平智, 臼井優, 樋口豪紀, 田村豊, 岩野英知
    • Organizer
      第6回乳房炎サマーキャンプ
    • Data Source
      KAKENHI-PROJECT-17H01506
  • [Presentation] 多価黄色ブドウ球菌ファージ由来エンドライシンの溶菌活性の検討2019

    • Author(s)
      藤木純平, 中村暢宏, 北名純也, 臼井優, 樋口豪紀, 田村豊, 岩野英知
    • Organizer
      第92回日本細菌学会総会
    • Data Source
      KAKENHI-PROJECT-17H01506
  • [Presentation] Mycoplasma bovisにおけるエンロフロキサシン耐性遺伝子の迅速検出技術の開発とその応用2019

    • Author(s)
      ○権平 智、西 航司、岩野直美、臼井 優、田村 豊、樋口豪紀
    • Organizer
      日本獣医師会獣医学術学会
    • Data Source
      KAKENHI-PROJECT-15K07749
  • [Presentation] バクテリオファージ由来溶菌酵素「エンドライシン」の構成能化の検討2018

    • Author(s)
      高橋宏充、北名純也、藤木純平、臼井優、樋口豪紀、田村豊、岩野英知
    • Organizer
      第7回ファージ研究会・2018年日本細菌学会関東支部インターラボセミナー合同大会
    • Data Source
      KAKENHI-PROJECT-17H01506
  • [Presentation] 黄色ブドウ球菌ファージ由来LysK様エンドライシン(LysφSA012)の機能解析2018

    • Author(s)
      藤木純平、中村暢宏、高橋宏充、北名純也、臼井優、古澤貴章、樋口豪紀、田村豊、岩野英知
    • Organizer
      第7回ファージ研究会・2018年日本細菌学会関東支部インターラボセミナー合同大会
    • Data Source
      KAKENHI-PROJECT-17H01506
  • [Presentation] Characterization of the Lytic Capability of Lys-phiSA012 Derived from a Polyvalent Staphylococcus aureus Bacteriophage2018

    • Author(s)
      FUJIKI Jumpei , TANJI Yasunori, HIGUCHI Hidetoshi and IWANO Hidetomo
    • Organizer
      5th World Congress on Targeting Infectious Diseases Targeting phage & antibiotic resistance
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H01506
  • [Presentation] 獣医療域におけるファージセラピーの可能性2018

    • Author(s)
      岩野 英知、藤木 純平、中村 暢宏、樋口 豪紀、樋口 優、田村 豊
    • Organizer
      第161回日本獣医学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H01506
  • [Presentation] Mycoplasma bovis 特異抗原を用いたELISA系の構築2018

    • Author(s)
      〇杉本侃司・西 航司・藤木純平・岩野英知・権平 智・樋口豪紀
    • Organizer
      日本家畜衛生学会
    • Data Source
      KAKENHI-PROJECT-15K07749
  • [Presentation] 薬剤耐性菌に対するファージセラピーの応用と展開2018

    • Author(s)
      藤木純平、臼井優、樋口豪紀、田村豊、岩野英知
    • Organizer
      Medical Cluster City Sapporo (MeCCS) フォーラム
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H01506
  • [Presentation] Bacteriophage ΦSA012 Has a Broad Host Range against Staphylococcus aureus and Effective Lytic Capacity in a Mouse Mastitis Model2018

    • Author(s)
      IWANO Hidetomo, FUJIKI Jumpei , TANJI Yasunori and HIGUCHI Hidetoshi
    • Organizer
      5th World Congress on Targeting Infectious Diseases Targeting phage & antibiotic resistance
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H01506
  • [Presentation] Mycoplasma bovisのウシ滑膜細胞に対する侵入と局在2018

    • Author(s)
      ○片方 美智子、西 航司、岡本 真理子、根布 貴則、藤木 純平、岩野 英知、萩原 克郎、権平 智、樋口 豪紀
    • Organizer
      第161回日本獣医学会学術集会
    • Data Source
      KAKENHI-PROJECT-15K07749
  • [Presentation] Distribution pattern of aerosolized Mycoplasma bovis with environmental aerosols under different humidity levels2017

    • Author(s)
      Noda, J., Saito, A., Nishi, K., Gondaira, S., Higuchi, H. Nagahata, H., Yokota, H.
    • Organizer
      Joint international Tropical Medicine Meeting, Bangkok, 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K00568
  • [Presentation] 子牛のマイコプラズマ関節炎罹患関節における免疫学的応答性の評価2017

    • Author(s)
      笹川操緒, 西航司, 岡本真理子, 田中貴大, 権平智, 根布貴則, 大塚浩通, 小岩政照, 松田一哉, 岩野英知, 樋口豪紀, 永幡肇
    • Organizer
      日本獣医学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H01506
  • [Presentation] 子牛のマイコプラズマ関節炎における骨融解の病態解明2017

    • Author(s)
      西航司, 権平智, 岡本真理子, 笹川操緒, 根布貴則, 岩野英知, 松田一哉, 大塚浩通, 小岩政照, 樋口豪紀, 永幡肇
    • Organizer
      日本獣医学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H01506
  • [Presentation] Mycoplasma bovisに対するウシ滑膜細胞の免疫学的応答性の解明2017

    • Author(s)
      岡本真理子, 西航司, 笹川操緒, 田中貴大, 権平智, 根布貴則, 大塚浩通, 松田一哉, 岩野英知, 小岩政照, 樋口豪紀, 永幡肇
    • Organizer
      日本獣医学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H01506
  • [Presentation] Behavior of airborne Mycoplasma bovis with different dusts in livestock farming2016

    • Author(s)
      J. Noda, A. Toyoda, H.Higuchi, H. Nagahata, and H. Yokota
    • Organizer
      DUST 2016 2nd International Conference on Atmospheric Dust
    • Place of Presentation
      Taranto, Italy
    • Year and Date
      2016-06-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K00568
  • [Presentation] Distribution pattern of Mycoplasma. bovis in different environmental aerosol2016

    • Author(s)
      Saitou A., Noda J, Toyoda, A., Higuchi, H., and Ngahata, H.
    • Organizer
      大気環境学会
    • Place of Presentation
      札幌
    • Year and Date
      2016-09-07
    • Data Source
      KAKENHI-PROJECT-15K00568
  • [Presentation] Evaluation of intramammary infusion of lactic acid bacteria and therapeutic effects on matitis in dairy cows.2016

    • Author(s)
      Nagahata, H., Horiguchi, M., Gondaira, S., Higuchi, H.
    • Organizer
      World Buiatrics Congress (Dublin, Ireland)
    • Place of Presentation
      Dublin International Conference Hall
    • Year and Date
      2016-07-04
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26450432
  • [Presentation] Mycoplasma bovisが子牛の滑膜細胞におけるサイトカイン遺伝子発現量に及ぼす影響2016

    • Author(s)
      西 航司・根布 貴則・権平 智・小岩 政照・樋口 豪紀・永幡 肇
    • Organizer
      日本マイコプラズマ学会
    • Place of Presentation
      長崎
    • Year and Date
      2016-06-24
    • Data Source
      KAKENHI-PROJECT-15K07749
  • [Presentation] 子牛のマイコプラズマ性関節炎における発病要因の検討.2016

    • Author(s)
      河合紀人、川本 哲、大塚浩通、鈴木一由、樋口豪紀、小岩政照
    • Organizer
      平成28年度北海道地区学会・産業動物獣医学会
    • Place of Presentation
      旭川市大雪クリスタルホール
    • Year and Date
      2016-09-01
    • Data Source
      KAKENHI-PROJECT-26450431
  • [Presentation] Mycoplasma bovis に対するウシ血清抗体価の測定2016

    • Author(s)
      田中 貴大・西 航司・権平 智・山本 剛史・田中 ふみ・小岩 政照・ 樋口 豪紀・永幡 肇
    • Organizer
      日本マイコプラズマ学会
    • Place of Presentation
      長崎
    • Year and Date
      2016-06-24
    • Data Source
      KAKENHI-PROJECT-15K07749
  • [Presentation] 牛乳房炎へのBifidobacterium breve注入に伴う乳腺の反応性とサイトカイン産生2016

    • Author(s)
      國分千尋、浅井友紀子、澤田知佳、丸山久美子、権平 智、樋口豪紀、永幡 肇
    • Organizer
      日本家畜衛生学会第85回大会
    • Place of Presentation
      Meiji Seika―ファルマ講堂
    • Year and Date
      2016-12-02
    • Data Source
      KAKENHI-PROJECT-26450432
  • [Presentation] Behavior of Airborne Mycoplasma Bovis with Different Dusts in Livestock Firming2016

    • Author(s)
      Noda, J., Toyoda, A., Higuchi, H., Ngahata, H., and Yokota, H
    • Organizer
      International Conference on Atmospheric dust
    • Place of Presentation
      Taranto, Italy
    • Year and Date
      2016-06-17
    • Data Source
      KAKENHI-PROJECT-15K00568
  • [Presentation] 獣医学領域で注目されているウシのマイコプラズマ感染症2016

    • Author(s)
      権平 智・樋口 豪紀・岩野 英知・永幡 肇
    • Organizer
      日本マイコプラズマ学会
    • Place of Presentation
      長崎
    • Year and Date
      2016-06-24
    • Data Source
      KAKENHI-PROJECT-15K07749
  • [Presentation] 牛乳房炎へのBifidobacterium breveおよびラクトフェリン分解産物注入に伴う乳腺の反応性とサイトカイン産生への影響2015

    • Author(s)
      澤田知佳、丸山久美子、浅井友紀子、国分千尋、権平智、河合一洋、樋口豪紀、永幡肇
    • Organizer
      日本家畜衛生学会
    • Place of Presentation
      東京Meiji Seika講堂
    • Year and Date
      2015-12-18
    • Data Source
      KAKENHI-PROJECT-26450432
  • [Presentation] Intramammary infusion of lactic acid bacteria and therapeutic effects on mastitis in dairy cows.2015

    • Author(s)
      Nagahata, H., M. Horiguchi, A. Tamiya, S. Gondaira, & H. Higuchi
    • Organizer
      2015 Congress of ISAH (International Society of Animal Health)
    • Place of Presentation
      Kosice, Slovakia
    • Year and Date
      2015-06-09
    • Data Source
      KAKENHI-PROJECT-26450432
  • [Presentation] Intramammary infusion of lactic acid bacteria and therapeutic effects on mastitis in dairy cows.2015

    • Author(s)
      Nagahata, H., M. Horiguchi, A. Tamiya, S. Gondaira, & H. Higuchi
    • Organizer
      XVII International Congress on Animal Hygiene
    • Place of Presentation
      Kocice, Slovakia
    • Year and Date
      2015-06-07
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26450432
  • [Presentation] 次世代シーケンサーによる緑膿菌とバクテリオファージのゲノム解析2015

    • Author(s)
      古澤 貴章、岩野 英知、樋口 豪紀、臼井 優、丸山 史人、中川 一路、 横田 博、田村 豊
    • Organizer
      第158回日本獣医学会学術集会
    • Place of Presentation
      北里大学
    • Year and Date
      2015-09-07
    • Data Source
      KAKENHI-PROJECT-25292182
  • [Presentation] 競走馬の細菌性角膜炎に対するファージセラピーの検討2014

    • Author(s)
      岩野英知 冷清水雄太郎 古澤貴章 樋口豪紀 萩原克郎 丹波秀和 片山芳也 木下優太 横田 博 田村 豊
    • Organizer
      北海道獣医師会
    • Place of Presentation
      北海道大学
    • Year and Date
      2014-09-11
    • Data Source
      KAKENHI-PROJECT-25292182
  • [Presentation] 牛乳房炎分房へのBifidobacterium breve注入に伴う乳腺の反応性とサイトカイン遺伝子発現2014

    • Author(s)
      堀口 萌、権平 智、樋口豪紀
    • Organizer
      日本家畜衛生学会 第81回大会
    • Place of Presentation
      東京Meiji Seikaファルマ講堂
    • Year and Date
      2014-11-29
    • Data Source
      KAKENHI-PROJECT-26450432
  • [Presentation] Mycoplasma 性乾酪性肺炎子牛における血清中アミノ酸動態.2014

    • Author(s)
      塚野健志、草場綾乃、嶋守俊雄、樋口豪紀、浅野隆司、鈴木一由.
    • Organizer
      平成26年度北海道獣医師会獣医学術地区学会
    • Place of Presentation
      北海道大学
    • Year and Date
      2014-09-11
    • Data Source
      KAKENHI-PROJECT-26450431
  • [Presentation] Characterization of novel Staphylococcus aureus bacteriophages with wide host ranges and their potential as therapeutic agents for bovine mastitis.2012

    • Author(s)
      Iwano, H., Higuchi, H., Inoue, H., Kobayashi, H., Nagahata, H., Yokota, H., Tanji, Y., Tamura, Y
    • Organizer
      World buiatrics congress 2012
    • Place of Presentation
      Lisbon
    • Data Source
      KAKENHI-PROJECT-22380174
  • [Presentation] Mycoplasma bovisがウシ単核球サイトカイン mRNA の発現量に及ぼす影響2012

    • Author(s)
      権平智、樋口豪紀、岩野英知、永幡肇
    • Organizer
      第153回日本獣医学会学術集会
    • Data Source
      KAKENHI-PROJECT-22380174
  • [Presentation] Mycoplasma bovisがウシ単核球サイトカインmRNAの発現量に及ぼす影響2012

    • Author(s)
      権平 智、樋口豪紀、岩野英知、永幡 肇
    • Organizer
      第154回日本獣医学会学術集会
    • Place of Presentation
      江別
    • Data Source
      KAKENHI-PROJECT-22380174
  • [Presentation] Characterization of novel Staphylococcus aureus bacteriophages with wide host ranges and their potential as therapeutic agents for bovine mastitis2012

    • Author(s)
      Iwano, H., Higuchi, H., Inoue, H., Kobayashi, H., Nagahata, H., Yokota, H. & Tanji, Y
    • Organizer
      World Buiatrics Congress
    • Place of Presentation
      Lisbon, Portugal
    • Year and Date
      2012-06-06
    • Data Source
      KAKENHI-PROJECT-22580354
  • [Presentation] Analysis of cellular and immune responses of dairy cows induced by intramammary infusion of lactic acid bacteria and therapeutic trials to quarters of cows with mastitis2012

    • Author(s)
      Nagahata, H., Moriyama, A., Koshi, A., Mukai, T., Natsume, Y., Higuchi, T., Koike, N. & Ando, T
    • Organizer
      World Buiatrics Congress
    • Place of Presentation
      Lisbon, Portugal
    • Year and Date
      2012-06-06
    • Data Source
      KAKENHI-PROJECT-22580354
  • [Presentation] 牛の気管支肺炎における肺胞洗浄液(BALF)中微量元素濃度2012

    • Author(s)
      鈴木一由、樋口豪紀、能田 淳、世良耕一郎
    • Organizer
      第17&18回NMCC 共同利用研究成果発表会 要旨集18.
    • Place of Presentation
      岩手医科大学
    • Year and Date
      2012-05-11
    • Data Source
      KAKENHI-PROJECT-21580393
  • [Presentation] 乳房炎由来ブドウ球菌に対するバクテリオファージの有効性と体内動態2012

    • Author(s)
      小林弘典、 岩野英知、 樋口豪紀、 井上博紀、萩原克郎、丹治保典、永幡肇、田村豊、横田博
    • Organizer
      第153回日本獣医学会学術集会
    • Data Source
      KAKENHI-PROJECT-22380174
  • [Presentation] 乳房炎由来ブドウ球菌に対するバクテリオファージの有効性と体内動態2012

    • Author(s)
      小林弘典、岩野英知、樋口豪紀、井上博紀、井上裕介、萩原克郎、丹治保典、永幡肇、田村豊、横田博
    • Organizer
      第153回日本獣医学会学術集会
    • Place of Presentation
      大宮ソニックシティー
    • Data Source
      KAKENHI-PROJECT-22380174
  • [Presentation] 子牛に対するビタミンE剤の投与が末梢血好中球のα-トコフェロール濃度に及ぼす影響2011

    • Author(s)
      樋口豪紀、北川詠子、間狩明美、吉田一万、郡和博、及川伸、永幡肇
    • Organizer
      第152回日本獣医学会学術集会集会
    • Data Source
      KAKENHI-PROJECT-21580380
  • [Presentation] 内視鏡による子牛中耳炎の病態評価および病態と臨床症状の比較2011

    • Author(s)
      小岩政照、安藤貴朗、甲斐貴憲、樋口豪紀
    • Organizer
      北海道獣医師会
    • Data Source
      KAKENHI-PROJECT-21580380
  • [Presentation] 子牛のマイコプラズマ性中耳炎に対する治療法の検討2011

    • Author(s)
      甲斐貴憲、安藤貴朗、樋口豪紀、小岩政照
    • Organizer
      北海道獣医師会
    • Data Source
      KAKENHI-PROJECT-21580380
  • [Presentation] マイコプラズマ性乳房炎の摘発を目的としたバルクスクリーニングの実施とその評価2011

    • Author(s)
      樋口豪紀、岩野英知、河合一洋、永幡肇
    • Organizer
      平成 23 年度北海道獣医師大会
    • Data Source
      KAKENHI-PROJECT-22380174
  • [Presentation] マイコプラズマ性乳房炎の摘発を目的としたバルクスクリーニングの実施とその評価2011

    • Author(s)
      樋口豪紀・岩野英知・河合一洋・馬場幸宏・古岡みゆき、斉藤哲・佐藤豊孝・大林哲・小岩政照・横田博・田村豊・永幡肇
    • Organizer
      北海道獣医師会
    • Data Source
      KAKENHI-PROJECT-21580380
  • [Presentation] ウシ乳房炎由来ブドウ球菌に対するバクテリオファージの有効性と体内動態2011

    • Author(s)
      小林弘典、岩野英知、樋口豪紀、井上博紀、井上裕介、萩原克郎、丹治保典、永幡肇、田村豊、横田博
    • Organizer
      第152回日本獣医学会学術集会
    • Place of Presentation
      大阪府立大学
    • Data Source
      KAKENHI-PROJECT-22380174
  • [Presentation] ウシ乳房炎由来ブドウ球菌に対するバクテリオファージの有効性と体内動態2011

    • Author(s)
      小林弘典、岩野英知、樋口豪紀、井上博紀、丹治保典、永幡肇、横田博、田村豊
    • Organizer
      第152回日本獣医学会学術集会
    • Data Source
      KAKENHI-PROJECT-22380174
  • [Presentation] 黄色ブドウ球菌感染症へのファージ療法の応用2010

    • Author(s)
      岩野英知、樋口豪紀、井上博紀、横田博、永幡肇、小倉俊樹、近藤明宏、丹治保典、田村豊
    • Organizer
      動物用ワクチン-バイオ医薬品研究会
    • Data Source
      KAKENHI-PROJECT-21580380
  • [Presentation] 黄色ブドウ球菌に対する特異的なファージを用いたウシ乳房炎治療応用への可能性2010

    • Author(s)
      岩野英知、樋口豪紀、井上博紀、萩原克郎、横田博、永幡肇、丹治保典、田村豊
    • Organizer
      日本乳房炎研究会第15回学術集会
    • Place of Presentation
      つくば国際会議場・茨城県つくば市
    • Data Source
      KAKENHI-PROJECT-22380174
  • [Presentation] 黄色ブドウ球菌感染症へのファージ療法の応用2010

    • Author(s)
      岩野英知、樋口豪紀、井上博紀、横田博、永幡肇、小倉俊樹、近藤昭宏、丹治保典、田村豊
    • Organizer
      動物用ワクチンーバイオ医薬品研究会設立記念シンポジウム
    • Place of Presentation
      日本獣医生命科学大学
    • Data Source
      KAKENHI-PROJECT-22380174
  • [Presentation] 黄色ブドウ球菌に対する特異的なファージを用いたウシ乳房炎治療応用への可能性2010

    • Author(s)
      岩野英知、樋口豪紀、 井上博紀、萩原克郎、横田博、永幡肇、丹治保典、田村豊
    • Organizer
      乳房炎研究会
    • Data Source
      KAKENHI-PROJECT-22380174
  • [Presentation] 細菌の遺伝子同定から乳房炎を防除する(特にマイコプラズマ性乳房炎について)2010

    • Author(s)
      樋口豪紀
    • Organizer
      日本乳房炎研究会
    • Data Source
      KAKENHI-PROJECT-21580380
  • [Presentation] 黄色ブドウ球菌の乳腺感染モデルマウスに対するファージセラピーの検討2010

    • Author(s)
      岩野英知、樋口豪紀、井上博紀、井上裕介、高砂拓志、萩原克郎、丹治保典、永幡肇、横田博
    • Organizer
      第150回日本獣医学会学術集会
    • Data Source
      KAKENHI-PROJECT-22380174
  • [Presentation] 牛乳房炎ファージセラピーに向けた黄色ブドウ球菌の凝集性評価2010

    • Author(s)
      丹治保典、谷夏織、栗本実樹、宮永一彦、樋口豪紀、岩野英知、井上博紀、永幡肇
    • Organizer
      日本乳房炎研究会
    • Data Source
      KAKENHI-PROJECT-21580380
  • [Presentation] ウシ乳房炎由来黄色ブドウ球菌に対するバクテリオファージの有効性2010

    • Author(s)
      井上裕介、英知、樋口豪紀、井上博紀、高砂拓志、萩原克郎、丹治保典、永幡肇、田村豊、横田博
    • Organizer
      第150回日本獣医学会学術集会
    • Place of Presentation
      帯広畜産大学・帯広
    • Data Source
      KAKENHI-PROJECT-22380174
  • [Presentation] 黄色ブドウ球菌に対する特異的ファージを用いたウシ乳房炎治療応用への可能性2010

    • Author(s)
      岩野英知、樋口豪紀、井上博紀、萩原克郎、横田博、永幡肇、田村豊
    • Organizer
      日本乳房炎研究会
    • Data Source
      KAKENHI-PROJECT-21580380
  • [Presentation] 北海道におけるウシ乳房炎由来マイコプラズマ種の浸潤調査2010

    • Author(s)
      伊藤暢彦、樋口豪紀、岩野英知、河合一洋、大林哲、永幡肇
    • Organizer
      平成 22 年度北海道獣医師大会
    • Data Source
      KAKENHI-PROJECT-22380174
  • [Presentation] 黄色ブドウ球菌の乳腺感染モデルマウスに対するファージセラピーの検討2010

    • Author(s)
      岩野英知、樋口豪紀、井上博紀、井上裕介、高砂拓志、萩原克郎、丹治保典、永幡肇、横田博
    • Organizer
      第149回日本獣医学会学術集会
    • Data Source
      KAKENHI-PROJECT-21580380
  • [Presentation] 牛マイコプラズマ性乳房炎の迅速簡易診断技術の開発とその応用に関する研究2010

    • Author(s)
      樋口豪紀・岩野英知・伊藤暢彦・河合一洋・草場信之・大林哲・廣瀬和彦・横田博・永幡肇
    • Organizer
      日本獣医師会
    • Data Source
      KAKENHI-PROJECT-21580380
  • [Presentation] PCR法を用いた乳房炎原因菌の迅速検出法に関する検討2008

    • Author(s)
      樋口豪紀・岩野英知・岩野直美・横田 博・永幡 肇
    • Organizer
      日本獣医学会学術集会
    • Place of Presentation
      神奈川
    • Year and Date
      2008-03-28
    • Data Source
      KAKENHI-PROJECT-19580362
  • [Presentation] マイコトキシンとウシ白血球:好中球化学発光能への影響2008

    • Author(s)
      難波江晶子・樋口豪紀・和田賢二・永幡肇
    • Organizer
      日本獣医学会学術集会
    • Place of Presentation
      宮崎
    • Year and Date
      2008-09-25
    • Data Source
      KAKENHI-PROJECT-19580362
  • [Presentation] Complement receptor type 3 (CR3)- and Fc receptor (FcR)-mediated matrix metalloproteinase 9 (MMP-9) secretion and their intracellular signaling of bovine neutrophils2008

    • Author(s)
      Higuchi, H. and Nagahata, H
    • Organizer
      世界牛病学会(WBC)
    • Place of Presentation
      Hungary
    • Year and Date
      2008-07-08
    • Data Source
      KAKENHI-PROJECT-19580362
  • [Presentation] 周産期乳牛における好中球α-トコフェロール濃度の評価2008

    • Author(s)
      北川詠子・間狩明美・樋口豪紀・永幡 肇
    • Organizer
      日本家畜衛生学会
    • Place of Presentation
      東京
    • Year and Date
      2008-11-07
    • Data Source
      KAKENHI-PROJECT-19580362
  • [Presentation] L.acidophilusの乳腺内注入が乳汁の細胞学的・理化学的性状におよぼす影響2008

    • Author(s)
      杉山瑞恵・田中雅委・樋口豪紀・永幡肇
    • Organizer
      日本家畜衛生学会
    • Place of Presentation
      東京
    • Year and Date
      2008-11-07
    • Data Source
      KAKENHI-PROJECT-19580362
  • [Presentation] Complement receptor type 3 (CR3)- and Fc receptor (FcR)-mediated matrix metalloproteinase 9 (MMP-9) secretion and their intracellular signaling of bovine neutrophils2008

    • Author(s)
      Higuchi, H., Nagahata, H.
    • Organizer
      世界牛病学会(WBC)
    • Place of Presentation
      Hungary (Budapest)
    • Year and Date
      2008-07-08
    • Data Source
      KAKENHI-PROJECT-19580362
  • [Presentation] ビタミンE剤投与がウシ白血球のα-Tocopherol量に及ぼす影響2007

    • Author(s)
      伊藤 えりな・坂井田 佳奈・樋口 豪紀・永幡 肇
    • Organizer
      第144回日本獣医学会
    • Place of Presentation
      酪農学園大学
    • Year and Date
      2007-09-03
    • Data Source
      KAKENHI-PROJECT-19580362
  • [Presentation] 搾乳過程における生乳の衛生学的ならびに理化学的性状の変化2007

    • Author(s)
      久保田友香・澤山成行・樋口豪紀・永幡肇
    • Organizer
      日本家畜衛生学会
    • Place of Presentation
      東京
    • Year and Date
      2007-11-22
    • Data Source
      KAKENHI-PROJECT-19580362
  • [Presentation] 大腸菌(O111:B4)によるウシ好中球活性酸素生成能の抑制について2007

    • Author(s)
      佐藤倫奈・山本千草・樋口豪紀・永幡 肇
    • Organizer
      第144回日本獣医学会
    • Place of Presentation
      江別
    • Year and Date
      2007-09-03
    • Data Source
      KAKENHI-PROJECT-19580362
  • [Presentation] 黄色ブドウ球菌に対するウシ好中球の化学発光反応2007

    • Author(s)
      大津治子・樋口豪紀・永幡肇
    • Organizer
      日本家畜衛生学会
    • Place of Presentation
      東京
    • Year and Date
      2007-11-22
    • Data Source
      KAKENHI-PROJECT-19580362
  • [Presentation] 搾乳過程における生乳の衛生学的ならびに理化学的性状の変化2007

    • Author(s)
      久保田 友香・澤山 成行・樋口 豪紀・永幡 肇
    • Organizer
      日本家畜衛生学会
    • Place of Presentation
      東京明治製菓本社講堂
    • Year and Date
      2007-11-22
    • Data Source
      KAKENHI-PROJECT-19580362
  • [Presentation] 黄色ブドウ球菌に対するウシ好中球の化学発光反応2007

    • Author(s)
      大津 治子・樋口 豪紀・永幡 肇
    • Organizer
      日本家畜衛生学会
    • Place of Presentation
      東京明治製菓本社講堂
    • Year and Date
      2007-11-22
    • Data Source
      KAKENHI-PROJECT-19580362
  • [Presentation] ビタミンE剤投与がウシ白血球のα-Tocopherol量に及ぼす影響2007

    • Author(s)
      伊藤えりな・坂井田佳奈・樋口豪紀・永幡 肇
    • Organizer
      第144回日本獣医学会
    • Place of Presentation
      江別
    • Year and Date
      2007-09-03
    • Data Source
      KAKENHI-PROJECT-19580362
  • [Presentation] 大腸菌(O111:B4)によるウシ好中球活性酸素生成能の抑制について2007

    • Author(s)
      佐藤 倫奈・山本 千草・樋口 豪紀・永幡 肇
    • Organizer
      第144回日本獣医学会
    • Place of Presentation
      酪農学園大学
    • Year and Date
      2007-09-03
    • Data Source
      KAKENHI-PROJECT-19580362
  • [Presentation] Characterization of novel Staphylococcus aureus bacteriophages with wide host ranges and their potential as therapeutic agents for bovine mastitis.

    • Author(s)
      Iwano, H., Higuchi, H., Inoue, H., Kobayashi, H., Nagahata, H., Yokota, H., Tanji, Y., Tamura, Y.
    • Organizer
      World buiatrics congress 2012
    • Place of Presentation
      リスボン(ポルトガル)
    • Data Source
      KAKENHI-PROJECT-22380174
  • [Presentation] 日本の酪農場におけるマイコプラズマ種の浸潤状況

    • Author(s)
      樋口豪紀・岩野英知
    • Organizer
      日本細菌学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24658260
  • [Presentation] 競走馬の細菌性角膜炎におけるファージセラピーの応用

    • Author(s)
      冷清水雄太郎 岩野英知 古澤貴章 樋口豪紀 萩原克郎 丹波秀和 片山芳也 木下優太 横田 博 田村 豊
    • Organizer
      日本獣医学会
    • Place of Presentation
      北海道大学
    • Year and Date
      2014-09-06 – 2014-09-08
    • Data Source
      KAKENHI-PROJECT-25292182
  • [Presentation] 北海道における子ウシ鼻腔内Mycoplasma 種の浸潤調査

    • Author(s)
      樋口豪紀、岩野英知、河合一洋、 榊原優子、佐藤豊孝、 小岩政照、 田村豊、 永幡肇
    • Organizer
      平成24年度獣医学術学会北海道地区学会・北海道獣医師大会
    • Place of Presentation
      江別
    • Data Source
      KAKENHI-PROJECT-22380174
  • [Presentation] 日本の酪農場におけるマイコプラズマ乳房炎の浸潤状況

    • Author(s)
      権平智・樋口豪紀・岩野英知・河合一洋・田村豊・永幡肇
    • Organizer
      日本マイコプラズマ学会
    • Place of Presentation
      東京大学
    • Year and Date
      2014-05-22 – 2014-05-23
    • Data Source
      KAKENHI-PROJECT-24658260
  • [Presentation] ウシ乳房炎由来黄色ブドウ球菌に対するバクテリオファージの有効性

    • Author(s)
      井上裕介、岩野英知、樋口豪紀、井上博紀、高砂拓志、萩原克郎、丹治保典、永幡肇、田村豊、横田博
    • Organizer
      第150回日本獣医学会学術集会
    • Data Source
      KAKENHI-PROJECT-21580380
  • [Presentation] 緑膿菌性角膜炎に対するファージセラピーの有効性

    • Author(s)
      古澤貴章、岩野英知、樋口豪紀、丹羽秀和、田村豊
    • Organizer
      日本細菌学会総会
    • Place of Presentation
      千葉
    • Data Source
      KAKENHI-PROJECT-25292182
  • [Presentation] 子牛のマイコプラズマ性中耳炎に対する抗菌剤による予防対策の検討

    • Author(s)
      谷美穂、安藤貴朗、樋口豪紀、小岩政照
    • Organizer
      北海道獣医師会
    • Data Source
      KAKENHI-PROJECT-21580380
  • [Presentation] 子牛鼻腔内マイコプラズマ種の浸潤状況

    • Author(s)
      吉田慎吾・樋口豪紀・権平 智・岩野英知・河合一洋・佐藤豊孝・
    • Organizer
      日本マイコプラズマ学会
    • Place of Presentation
      東京大学
    • Year and Date
      2014-05-22 – 2014-05-23
    • Data Source
      KAKENHI-PROJECT-24658260
  • [Presentation] 競走馬の細菌性角膜炎に対するファージセラピーの検討

    • Author(s)
      岩野英知 冷清水雄太郎 古澤貴章 樋口豪紀 萩原克郎 丹波秀和 片山芳也 木下優太 岩崎智仁 横田 博 田村 豊
    • Organizer
      日本獣医師会
    • Place of Presentation
      岡山コンベンションセンター
    • Year and Date
      2015-02-13 – 2015-02-15
    • Data Source
      KAKENHI-PROJECT-25292182
  • [Presentation] 牛の気管支肺炎における肺胞洗浄液(BALF)中微量元素濃度.

    • Author(s)
      鈴木一由、樋口豪紀、能田 淳、世良耕一郎
    • Organizer
      第17&18回NMCC共同利用研究成果発表会
    • Place of Presentation
      岩手医科大学
    • Data Source
      KAKENHI-PROJECT-21580393
  • [Presentation] 黄色ブドウ球菌によるウシ乳房炎へのファージ療法応用に関する検討

    • Author(s)
      岩野英知、樋口豪紀、古澤貴章、田村豊
    • Organizer
      日本細菌学会総会
    • Place of Presentation
      千葉
    • Data Source
      KAKENHI-PROJECT-25292182
  • [Presentation] 緑膿菌性角膜炎に対するファージセラピーの有効性について

    • Author(s)
      古澤貴章、岩野英知、冷清水健太郎、樋口豪紀、萩原克郎、横田博、田村豊
    • Organizer
      日本獣医学会
    • Place of Presentation
      岐阜
    • Data Source
      KAKENHI-PROJECT-25292182
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